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In order to achieve noticeable material strengthening via solution strengthening, one should alloy with solutes of higher shear modulus, hence increasing the local shear modulus in the material. In addition, one should alloy with elements of different equilibrium lattice constants. The greater the difference in lattice... | 0 | Metallurgy |
The SIP peptide binding pocket is the docking station of the eight amino acid leaderless peptide signal, speB-inducing peptide (SIP). The binding pocket is a tripartite construction of the C-terminals α12 helix which is a capping helix, TPR3s α6 helix that has a hydrophobic interplay with SIP sidechains, and TPR 4's α8... | 1 | Gene expression + Signal Transduction |
Recyclability is a key factor of a sustainable material. It reduces the need to mine new resources and requires less energy than mining. Copper and its alloys are virtually 100% recyclable and can be recycled infinitely without any loss of quality (i.e., copper does not degrade (i.e., downcycle) after each recycling lo... | 0 | Metallurgy |
Monoallelic gene expression (MAE) is the phenomenon of the gene expression, when only one of the two gene copies (alleles) is actively expressed (transcribed), while the other is silent. Diploid organisms bear two homologous copies of each chromosome (one from each parent), a gene can be expressed from both chromosomes... | 1 | Gene expression + Signal Transduction |
Shape-memory alloys are applied in medicine, for example, as fixation devices for osteotomies in orthopaedic surgery, as the actuator in surgical tools; active steerable surgical needles for minimally invasive percutaneous cancer interventions in the surgical procedures such as biopsy and brachytherapy, in dental brac... | 0 | Metallurgy |
Filiform corrosion may be considered as a type of crevice corrosion and is sometimes seen on metals coated with an organic coating (paint). Filiform corrosion is unusual in that it does not weaken or destroy the integrity of the metal but only affects the surface appearance. | 0 | Metallurgy |
Mediator is involved in "looping" of chromatin, which brings distant regions of a chromosome into closer physical proximity. The ncRNA-a mentioned above is involved in such looping. Enhancer RNAs (eRNAs) can function similarly.
In addition to the looping of euchromatin, mediator appears to be involved in formation or m... | 1 | Gene expression + Signal Transduction |
Extensive research has been carried out on the metallurgical material from Tell Hammeh. Both excavation and archaeometric analyses were carried out by Dr H.A. Veldhuijzen, first at Leiden University, then since 2001 at the UCL Institute of Archaeology, as a part of the joint excavations conducted by Yarmouk University ... | 0 | Metallurgy |
Fas signaling pathway involves activating apoptosis (programmed cell death). This happens through the interaction of Fas receptor and Fas ligand. As mentioned, Fas ligand/FasL is a type II transmembrane protein that can exist in both membrane-anchored and soluble forms. The interaction between FasR on an adjacent cell ... | 1 | Gene expression + Signal Transduction |
The two N-terminal cysteines of CXC chemokines (or α-chemokines) are separated by one amino acid, represented in this name with an "X". There have been 17 different CXC chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine... | 1 | Gene expression + Signal Transduction |
Center-surround antagonism refers to antagonistic interactions between center and surround regions of the receptive fields of photoreceptor cells in the retina. Center surround antagonism enables edge detection and contrast enhancement within the visual cortex. | 1 | Gene expression + Signal Transduction |
Experimental work on precious metals is limited by the cost of experimentation and by the well-understood technical processes involved. Gold and silver are produced in a similar manner to copper with the additional process of cupellation. Platinum is mostly an issue in South America and is typically left out from exper... | 0 | Metallurgy |
This book describes the miner and the finding of veins. Agricola assumes that his audience is the mine owner, or an investor in mines. He advises owners to live at the mine and to appoint good deputies. It is recommended to buy shares in mines that have not started to produce as well as existing mines to balance the ri... | 0 | Metallurgy |
Fretting refers to wear and sometimes corrosion damage of loaded surfaces in contact while they encounter small oscillatory movements tangential to the surface. Fretting is caused by adhesion of contact surface asperities, which are subsequently broken again by the small movement. This breaking causes wear debris to ... | 0 | Metallurgy |
In these processes, iron ore is brought into contact with reducing gases produced and heated by a separate plant in a closed enclosure. As a result, these processes are naturally suited to the use of natural gas. | 0 | Metallurgy |
The TGF-β pathway regulates many cellular processes in developing embryo and adult organisms, including cell growth, differentiation, apoptosis, and homeostasis. There are five kinds of type II receptors and seven types of type I receptors in humans and other mammals. These receptors are known as "dual-specificity kina... | 1 | Gene expression + Signal Transduction |
Deflocculation is the exact opposite of flocculation, also sometimes known as peptization. Sodium silicate (NaSiO) is a typical example. Usually in higher pH ranges in addition to low ionic strength of solutions and domination of monovalent metal cations the colloidal particles can be dispersed.
The additive that preve... | 0 | Metallurgy |
Early European bloomeries were relatively small, primarily due to the mechanical limits of human-powered bellows and the amount of force possible to apply with hand-driven sledge hammers. Those known archaeologically from the pre-Roman Iron Age tend to be in the 2 kg range, produced in low shaft furnaces. Roman-era pro... | 0 | Metallurgy |
The most widely used anodizing specification in the US is a U.S. military spec, MIL-A-8625, which defines three types of aluminium anodizing. Type I is chromic acid anodizing, Type II is sulphuric acid anodizing, and Type III is sulphuric acid hard anodizing. Other anodizing specifications include more MIL-SPECs (e.g.,... | 0 | Metallurgy |
FAIRE-Seq (Formaldehyde-Assisted Isolation of Regulatory Elements) is a method in molecular biology used for determining the sequences of DNA regions in the genome associated with regulatory activity. The technique was developed in the laboratory of Jason D. Lieb at the University of North Carolina, Chapel Hill. In con... | 1 | Gene expression + Signal Transduction |
Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3,5-cyclic adenosine monophosphate) is a second messenger, or cellular signal occurring within cells, that is important in many biological processes. cAMP is a derivative of adenosine triphosphate (ATP) and used for intracellular signal transduction in many differen... | 1 | Gene expression + Signal Transduction |
In another setting, the chambers are connected side by side horizontally (Zigmond chamber) or as concentric rings on a slide (Dunn chamber) Concentration gradient develops on a narrow connecting bridge between the chambers and the number of migrating cells is also counted on the surface of the bridge by light microscop... | 1 | Gene expression + Signal Transduction |
Romans used many methods to create metal objects. Like Samian ware, moulds were created by making a model of the desired shape (whether through wood, wax, or metal), which would then be pressed into a clay mould. In the case of a metal or wax model, once dry, the ceramic could be heated and the wax or metal melted un... | 0 | Metallurgy |
The histone code is a hypothesis that the transcription of genetic information encoded in DNA is in part regulated by chemical modifications to histone proteins, primarily on their unstructured ends. Together with similar modifications such as DNA methylation it is part of the epigenetic code.
Cumulative evidence sugg... | 1 | Gene expression + Signal Transduction |
There are ten known isoforms of adenylyl cyclases in mammals:
These are also sometimes called simply AC1, AC2, etc., and, somewhat confusingly, sometimes Roman numerals are used for these isoforms that all belong to the overall AC class III. They differ mainly in how they are regulated, and are differentially expressed... | 1 | Gene expression + Signal Transduction |
Prior to the formation of the lactate shuttle hypothesis, lactate had long been considered a byproduct resulting from glucose breakdown through glycolysis in times of anaerobic metabolism. As a means of regenerating oxidized NAD, lactate dehydrogenase catalyzes the conversion of pyruvate to lactate in the cytosol, ox... | 1 | Gene expression + Signal Transduction |
In eukaryotic transcription of mRNAs, terminator signals are recognized by protein factors that are associated with the RNA polymerase II and which trigger the termination process. The genome encodes one or more polyadenylation signals. Once the signals are transcribed into the mRNA, the proteins cleavage and polyadeny... | 1 | Gene expression + Signal Transduction |
The Museum Weavers are housed in a barn, featuring more than 50 working looms for weaving. Members of this club meet weekly to learn and practice weaving, rug-making and rope-making. | 0 | Metallurgy |
Nuclear receptor-interacting protein 1 (NRIP1) also known as receptor-interacting protein 140 (RIP140) is a protein that in humans is encoded by the NRIP1 gene. | 1 | Gene expression + Signal Transduction |
Hydrogen probes are used to monitor the penetration of hydrogen into steels, which can cause brittleness, porosity or decarbonization. | 0 | Metallurgy |
Wrought iron is no longer made. The particles of slag present in the iron after preparation by puddling were drawn into long fibres during the forging or rolling process. The proportion of slag was intended to be about 3%, but the process was difficult to control and examples with up to 10% slag were produced. | 0 | Metallurgy |
Considerable effort and research continues to be made into discovering and refining better methods of tailings disposal. Research at the Porgera Gold Mine is focusing on developing a method of combining tailings products with coarse waste rock and waste muds to create a product that can be stored on the surface in gene... | 0 | Metallurgy |
Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. It is a member of the STAT protein family. | 1 | Gene expression + Signal Transduction |
The fim switch in Escherichia coli is the mechanism by which the fim gene cluster, encoding Type I Pili, is transcriptionally controlled.
These pili are virulence factors involved in adhesion, especially important in uropathogenic Escherichia coli. The gene undergoes phase variation mediated via two recombinases and is... | 1 | Gene expression + Signal Transduction |
The discovery of this type of mechanism to control the expression of genes in a biosynthetic operon lead to its identification in a wide variety of such operons for which repressors had never been discovered. For example: | 1 | Gene expression + Signal Transduction |
Fresh domestic sewage entering a wastewater collection system contains proteins including organic sulfur compounds oxidizable to sulfates and may contain inorganic sulfates. Dissolved oxygen is depleted as bacteria begin to catabolize organic material in sewage. In the absence of dissolved oxygen and nitrates, sulfat... | 0 | Metallurgy |
One well-studied eRNA is the eRNA of the enhancer that interacts with the promoter of the prostate specific antigen (PSA) gene. The PSA eRNA is strongly up-regulated by the androgen receptor. High PSA eRNA then has a domino effect. PSA eRNA binds to and activates the positive transcription elongation factor P-TEFb p... | 1 | Gene expression + Signal Transduction |
Small GTPases, also known as small G-proteins, bind GTP and GDP likewise, and are involved in signal transduction. These proteins are homologous to the alpha (α) subunit found in heterotrimers, but exist as monomers. They are small (20-kDa to 25-kDa) proteins that bind to guanosine triphosphate (GTP). This family of p... | 1 | Gene expression + Signal Transduction |
The deposits consist of a multitude of pancake-like splats called lamellae, formed by flattening of the liquid droplets. As the feedstock powders typically have sizes from micrometers to above 100 micrometers, the lamellae have thickness in the micrometer range and lateral dimension from several to hundreds of micromet... | 0 | Metallurgy |
The alkA gene product is a glycosylase that can repair a variety of lesions, removing a base from the sugar-phosphate backbone, producing an abasic site. | 1 | Gene expression + Signal Transduction |
RNA polymerase II (also called RNAP II and Pol II) is an enzyme found in eukaryotic cells. It catalyzes the transcription of DNA to synthesize precursors of mRNA and most snRNA and microRNA. In humans, RNAP II consists of seventeen protein molecules (gene products encoded by POLR2A-L, where the proteins synthesized fro... | 1 | Gene expression + Signal Transduction |
Scholarly information about the use of gold in early Philippine history comes mostly from artifacts that have been discovered in various sites in the Philippines, and from historical accounts from the early Spanish colonial period. Archeological excavation sites include ones in Batangas, Mindoro, Luzon, Samar, Butuan a... | 0 | Metallurgy |
The Mark IV Cell design was introduced in 2009. It included the following improvements:
* a flexible hose for easier alignment of the downcomer
* clamping of the slurry lens onto the downcomer (see Figure 10)
* stainless steel quick-release clamps in the downcomer assembly
* long-lasting rubber flaps in the AISE valves... | 0 | Metallurgy |
Recent excavations in Middle Ganga Valley done by archaeologist Rakesh Tewari show iron working in India may have begun as early as 1800 BCE. Archaeological sites in India, such as Malhar, Dadupur, Raja Nala Ka Tila and Lahuradewa in the state of Uttar Pradesh show iron implements in the period between 1800 BCE – 1200 ... | 0 | Metallurgy |
The U.S. Institute of Medicine (IOM) established Recommended Dietary Allowances (RDAs) for calcium in 1997 and updated those values in 2011. See table. The
European Food Safety Authority (EFSA) uses the term Population Reference Intake (PRIs) instead of RDAs and sets slightly different numbers: ages 4–10 800 mg, ages ... | 1 | Gene expression + Signal Transduction |
The Jameson Cell has been found to be particularly effective in cleaning and recovering fine coal particles. For example, at BHP Coal's Goonyella mine (now part of the BHP Mitsubishi Alliance) eight Cells were installed to replace the entire 32 mechanical cell flotation circuit in 1995 in its 1800 t/h coal flotation pl... | 0 | Metallurgy |
The initial laser systems used during the development of laser peening were large research lasers providing high-energy pulses at very low pulse frequencies. Since the mid-late 1990s, lasers designed specifically for laser peening featured steadily smaller size and higher pulse frequencies, both of these more desirable... | 0 | Metallurgy |
The process of DNA replication inherently places cells at risk of acquiring mutations. Thus, caretaker genes are vitally important to cellular health. Rounds of cell replication allow fixation of mutated genes into the genome. Caretaker genes provide genome stability by preventing the accumulation of these mutations.... | 1 | Gene expression + Signal Transduction |
Conformal compound coatings stop the whiskers from penetrating a barrier, reaching a nearby termination and forming a short. | 0 | Metallurgy |
Laser peening uses the dynamic mechanical effects of a shock wave imparted by a laser to modify the surface of a target material. It does not utilize thermal effects. Fundamentally, laser peening can be accomplished with only two components: a transparent overlay and a high-energy pulsed laser system. The transparent o... | 0 | Metallurgy |
Many waters in both the UK and Europe are capable of supporting Type 1 pitting but no problems will be experienced unless a pit is initiated in the wall of the tube. When a copper tube is initially filled with a hard water salts deposit on the wall and the copper slowly reacts with the water producing a thin protective... | 0 | Metallurgy |
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This process is not 100% efficient. At the Lautenthal, Altenau, and Sankt Andreasberg smelting-works in the Upper Harz between 1857 and 1860 25% of the silver, 25.1% of the lead and 9.3% of the copper was lost. Some of this is lost in slag that is not worth reusing, some is lost by what is termed ‘burning’, and some of... | 0 | Metallurgy |
The largest subunit of Pol II (Rpb1) has a domain at its C-terminus called the CTD (C-terminal domain). This is the target of kinases and phosphatases. The phosphorylation of the CTD is an important regulation mechanism, as this allows attraction and rejection of factors that have a function in the transcription proces... | 1 | Gene expression + Signal Transduction |
The Arthashastra lays down the role of the Director of Metals, the Director of Forest Produce and the Director of Mining. It is the duty of the Director of Metals to establish factories for different metals. The Director of Mines is responsible for the inspection of mines. The Arthashastra also refers to counterfeit co... | 0 | Metallurgy |
Bacteria depend on transcription-translation coupling for genome integrity, termination of transcription and control of mRNA stability. Consequently, artificial disruption of transcription-translation coupling impairs the fitness of bacteria. Without coupling, genome integrity is compromised as stalled transcription co... | 1 | Gene expression + Signal Transduction |
The cam is actuated by a user by rotating the handle, causing a cam to lift the weight and let it fall freely on the frame attached to the ram head. This produces a standard compacting action to a pre-measured amount of sand. Demonstration of this apparatus can be seen here:
Variety of standard specimen for Green San... | 0 | Metallurgy |
Different elements serve different roles in the solder alloy:
* Antimony is added to increase strength without affecting wettability. Prevents tin pest. Should be avoided on zinc, cadmium, or galvanized metals as the resulting joint is brittle.
* Bismuth significantly lowers the melting point and improves wettability. ... | 0 | Metallurgy |
The addition of the myristoyl group proceeds via a nucleophilic addition-elimination reaction. First, myristoyl coenzyme A (CoA) is positioned in its binding pocket of NMT so that the carbonyl faces two amino acid residues, phenylalanine 170 and leucine 171. This polarizes the carbonyl so that there is a net positive c... | 1 | Gene expression + Signal Transduction |
Some forms of ribosomal pause are reversible without needing to discard the translated peptide and mRNA. This sort, usually described as a slowdown, is usually caused by polyproline stretches (resolved by EFP or eIF5A) and uncharged tRNA. Slowdowns are important for the cell to control how much protein is produced; it ... | 1 | Gene expression + Signal Transduction |
The most common anodizing processes, for example, sulphuric acid on aluminium, produce a porous surface which can accept dyes easily. The number of dye colours is almost endless; however, the colours produced tend to vary according to the base alloy. The most common colours in the industry, due to them being relatively... | 0 | Metallurgy |
A crystallite is a small or even microscopic crystal which forms, for example, during the cooling of many materials. Crystallites are also referred to as grains.
Bacillite is a type of crystallite. It is rodlike with parallel longulites. | 0 | Metallurgy |
Nanocrystalline materials can be prepared in several ways. Methods are typically categorized based on the phase of matter the material transitions through before forming the nanocrystalline final product. | 0 | Metallurgy |
eIF2 is a heterotrimer of a total molar mass of 126 kDa that is composed of the three sub-units: α (sub-unit 1), β (sub-unit 2), and γ (sub-unit 3).
The sequences of all three sub-units are highly conserved (pairwise amino acid identities for each sub-unit range from 47 to 72% when comparing the proteins of Homo sapie... | 1 | Gene expression + Signal Transduction |
The atmosphere of Early Earth is widely speculated to have been reducing. The Miller–Urey experiment, related to some hypotheses for the origin of life, entailed reactions in a reducing atmosphere composed of a mixed atmosphere of methane, ammonia and hydrogen sulfide. Some hypotheses for the origin of life invoke a r... | 0 | Metallurgy |
The number of RNAPs in bacterial cells (e.g., E. coli) have been shown to be smaller than the number of sigma factors. Consequently, if a certain sigma factor is overexpressed, not only will increase the expression levels of genes whose promoters have preference for that sigma factor, but it will also reduce the probab... | 1 | Gene expression + Signal Transduction |
Due to the scattered nature of tin deposits around the world and its essential nature for the creation of tin bronze, tin trade played an important role in the development of cultures throughout ancient times. Archaeologists have reconstructed parts of the extensive trade networks of ancient cultures from the Bronze Ag... | 0 | Metallurgy |
The first ncRNA therapeutic drug approved by food and drug administration (FDA) (1998) and the European medicine agency (EMA) (1999) is called Fomivirsen or Vitravene. The target organ is the eye and works against the cytomegalovirus (CMV) retinitis in immunocompromised patients. The drug functions as an antisense olig... | 1 | Gene expression + Signal Transduction |
*Metallurgical and Materials Transactions A – [https://link.springer.com/search?query=&search-within=Journal&facet-journal-id=11661&package=openaccessarticles open access articles]
*Metallurgical and Materials Transactions B – [https://link.springer.com/search?query=&search-within=Journal&facet-journal-id=11663&package... | 0 | Metallurgy |
Catenin beta-1, also known as β-catenin (beta-catenin), is a protein that in humans is encoded by the CTNNB1 gene.
β-Catenin is a dual function protein, involved in regulation and coordination of cell–cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the h... | 1 | Gene expression + Signal Transduction |
Prior to 1907, nearly all the copper mined in the US came from underground vein deposits, averaging 2.5 percent copper. By 1991, the average grade of copper ore mined in the US had fallen to only 0.6 percent. | 0 | Metallurgy |
Tin deposits exist in many parts of South America, with minor deposits in southern Peru, Colombia, Brazil, and northwestern Argentina, and major deposits of exploitable cassiterite in northern Bolivia. These deposits were exploited as early as 1000 AD in the manufacture of tin bronze by Andean cultures, including the l... | 0 | Metallurgy |
The susceptibility to crevice corrosion varies widely from one material-environment system to another. In general, crevice corrosion is of greatest concern for materials which are normally passive metals, like stainless steel or aluminum. Crevice corrosion tends to be of greatest significance to components built of hig... | 0 | Metallurgy |
This method is mostly used for corrosion monitoring in water industry. These probes are suitable for monitoring fluctuations that may occur in a fluid inside the system. These probes are mostly used for conductive fluids such as water or any similar else. | 0 | Metallurgy |
In sporadic cancers, a DNA repair deficiency is occasionally found to be due to a mutation in a DNA repair gene. However, much more frequently, reduced or absent expression of a DNA repair gene in cancer is due to methylation of its promoter. For example, of 113 colorectal cancers examined, only four had a missense m... | 1 | Gene expression + Signal Transduction |
Tripartite motif-containing 28 (TRIM28), also known as transcriptional intermediary factor 1β (TIF1β) and KAP1 (KRAB-associated protein-1), is a protein that in humans is encoded by the TRIM28 gene. | 1 | Gene expression + Signal Transduction |
When nascent hydrogen is produced by anaerobic corrosion of iron by the protons of water, the atomic hydrogen can diffuse into the metal crystal lattice because of the existing concentration gradient. After diffusion, hydrogen atoms can recombine into molecular hydrogen giving rise to the formation of high-pressure mic... | 0 | Metallurgy |
Wootz steel has been reproduced and studied in depth by the Royal School of Mines. Dr. Pearson was the first to chemically examine wootz in 1795 and he published his contributions to the Philosophical Transactions of the Royal Society.
Russian metallurgist Pavel Petrovich Anosov (see Bulat steel) was almost able to rep... | 0 | Metallurgy |
Sepro Mineral Systems Corp. is a Canadian company founded in 1987 and headquartered in British Columbia, Canada. The outcome of the acquisition of Sepro Mineral Processing International by Falcon Concentrators in 2008, the company's key focus is the production of mineral processing equipment for the mining and aggregat... | 0 | Metallurgy |
A Morpholino, also known as a Morpholino oligomer and as a phosphorodiamidate Morpholino oligomer (PMO), is a type of oligomer molecule (colloquially, an oligo) used in molecular biology to modify gene expression. Its molecular structure contains DNA bases attached to a backbone of methylenemorpholine rings linked thro... | 1 | Gene expression + Signal Transduction |
The reaction happens with two metal cofactors (Mg or Mn) coordinated to the two aspartate residues on C1. They perform a nucleophilic attack of the 3'-OH group of the ribose on the α-phosphoryl group of ATP. The two lysine and aspartate residues on C2 selects ATP over GTP for the substrate, so that the enzyme is not a ... | 1 | Gene expression + Signal Transduction |
The high-frequency impact treatment or HiFIT – Method is the treatment of welded steel constructions at the weld transition to increase the fatigue strength. | 0 | Metallurgy |
VMAT1 (SLC18A1) maps to a shared bipolar disorder(BPD)/schizophrenia locus, which is located on chromosome 8p21. It is thought that disruption in transport of monoamine neurotransmitters due to variation in the VMAT1 gene may be relevant to the etiology of these mental disorders. One study looked at a population of E... | 1 | Gene expression + Signal Transduction |
The regulation of translation in eukaryotes is more complex than in prokaryotes. Initially, the eIF4F complex is recruited to the 5′ cap, which in turn recruits the ribosomal complex to the 5′ UTR. Both eIF4E and eIF4G bind the 5′ UTR, which limits the rate at which translational initiation can occur. However, this is ... | 1 | Gene expression + Signal Transduction |
Post-translational regulation refers to the control of the levels of active protein.
There are several forms.
It is performed either by means of reversible events (posttranslational modifications, such as phosphorylation or sequestration) or by means of irreversible events (proteolysis). | 1 | Gene expression + Signal Transduction |
Tensioned screen cloth is typically 4 feet by the width or the length of the screening machine depending on whether the deck is side or end tensioned. Screen cloth for tensioned decks can be made with hooks and are attached with clamp rails bolted on both sides of the screen box. When the clamp rail bolts are tighten... | 0 | Metallurgy |
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by the PCAF gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and compe... | 1 | Gene expression + Signal Transduction |
There are several different techniques to detect regulatory genes, but of the many there are a certain few that are used more frequently than others. One of these select few is called ChIP-chip. ChIP-chip is an in vivo technique used to determine genomic binding sites for transcription factors in two component system... | 1 | Gene expression + Signal Transduction |
The Hedgehog protein family is involved in induction of cell types and the creation of tissue boundaries and patterning and are found in all bilateral organisms. Hedgehog proteins were first discovered and studied in Drosophila. Hedgehog proteins produce key signals for the establishment of limb and body plan of fruit... | 1 | Gene expression + Signal Transduction |
myo-Inositol trispyrophosphate (ITPP) is an inositol phosphate, a pyrophosphate, a drug candidate, and a putative performance-enhancing substance, which exerts its biological effects by increasing tissue oxygenation. | 1 | Gene expression + Signal Transduction |
Stainless steel forms a passivation layer of chromium(III) oxide. Similar passivation behavior occurs with magnesium, titanium, zinc, zinc oxides, aluminium, polyaniline, and other electroactive conductive polymers.
Special "weathering steel" alloys such as Cor-Ten rust at a much slower rate than normal, because the ru... | 0 | Metallurgy |
The blast furnaces used in the Imperial Smelting Process ("ISP") were developed from the standard lead blast furnace, but are fully sealed. This is because the zinc produced by these furnaces is recovered as metal from the vapor phase, and the presence of oxygen in the off-gas would result in the formation of zinc oxid... | 0 | Metallurgy |
The low-density lipoprotein receptor gene family codes for a class of structurally related cell surface receptors that fulfill diverse biological functions in different organs, tissues, and cell types. The role that is most commonly associated with this evolutionarily ancient family is cholesterol homeostasis (maintena... | 1 | Gene expression + Signal Transduction |
In molecular biology, ribosomal s6 kinase (rsk) is a family of protein kinases involved in signal transduction. There are two subfamilies of rsk, p90, also known as MAPK-activated protein kinase-1 (MAPKAP-K1), and p70, also known as S6-H1 Kinase or simply S6 Kinase. There are three variants of p90 in humans, rsk 1-3.... | 1 | Gene expression + Signal Transduction |
In eukaryotes, a corepressor is a protein that binds to transcription factors. In the absence of corepressors and in the presence of coactivators, transcription factors upregulate gene expression. Coactivators and corepressors compete for the same binding sites on transcription factors. A second mechanism by which cor... | 1 | Gene expression + Signal Transduction |
Native silver is a rare element. Although it exists as such, it is usually found in nature combined with other metals, or in minerals that contain silver compounds, generally in the form of sulfides such as galena (lead sulfide) or cerussite (lead carbonate). So the primary production of silver requires the smelting an... | 0 | Metallurgy |
Microarrays can be fabricated using a variety of technologies, including printing with fine-pointed pins onto glass slides, photolithography using pre-made masks, photolithography using dynamic micromirror devices, ink-jet printing, or electrochemistry on microelectrode arrays.
In spotted microarrays, the probes are ol... | 1 | Gene expression + Signal Transduction |
In wire and fiber, all crystals tend to have nearly identical orientation in the axial direction, but nearly random radial orientation. The most familiar exceptions to this rule are fiberglass, which has no crystal structure, and carbon fiber, in which the crystalline anisotropy is so great that a good-quality filament... | 0 | Metallurgy |
MAPK pathways of fungi are also well studied. In yeast, the Fus3 MAPK is responsible for cell cycle arrest and mating in response to pheromone stimulation. The pheromone alpha-factor is sensed by a seven transmembrane receptor. The recruitment and activation of Fus3 pathway components are strictly dependent on heterotr... | 1 | Gene expression + Signal Transduction |
Carbon steel consists of two components: pure iron, in the form of ferrite, and cementite or iron carbide, a compound of iron and carbon. Cementite is very hard and brittle; its hardness is about 640 by the Brinell hardness test, whereas ferrite is only 200. The amount of the carbon and the cooling regimen determine th... | 0 | Metallurgy |
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