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Agroinfiltration is a method used in plant biology and especially lately in plant biotechnology to induce transient expression of genes in a plant, or isolated leaves from a plant, or even in cultures of plant cells, in order to produce a desired protein. In the method, a suspension of Agrobacterium tumefaciens is intr... | 1 | Gene expression + Signal Transduction |
To produce a ton of steel in an electric arc furnace requires approximately 400 kilowatt-hours (1.44 gigajoules) per short ton or about 440 kWh (1.6 GJ) per tonne. The theoretical minimum amount of energy required to melt a tonne of scrap steel is 300 kWh (1.09 GJ) (melting point ). Therefore, a 300-tonne, 300 MVA EAF ... | 0 | Metallurgy |
PT clearly plays a central role in the pathogenesis of pertussis although this was discovered only in the early 1980s. The appearance of pertussis is quite recent, compared with other epidemic infectious diseases. The earliest mention of pertussis, or whooping cough, is of an outbreak in Paris in 1414. This was publish... | 1 | Gene expression + Signal Transduction |
Corepressors are known to regulate transcription through different activation and inactivation states.
NCoR and SMRT act as a corepressor complex to regulate transcription by becoming activated once the ligand is bound. Knockouts of NCoR resulted in embryo death, indicating its importance in erythrocytic, thymic, and n... | 1 | Gene expression + Signal Transduction |
While repeatedly reversed loading commonly leads to localisation of dislocation glide, creating linear extrusions and intrusions on a free surface, similar features can arise even if there is no load reversal. These arise from dislocations gliding on a particular slip plane, in a particular slip direction (within a si... | 0 | Metallurgy |
The old MIL-F-14256 and QQ-S-571 standards defined fluxes as:
*R (rosin)
*RMA (rosin mildly activated)
*RA (rosin activated)
*WS (water-soluble)
Any of these categories may be no-clean, or not, depending on the chemistry selected and the standard that the manufacturer requires. | 0 | Metallurgy |
When an initially homogenous alloy is placed in an acid that can preferentially dissolve one or more components out of the alloy, the remaining component will diffuse and organize into a unique, nano-porous microstructure. The resulting material will have ligaments, formed by the remaining material, surrounded by pores... | 0 | Metallurgy |
Masahiro Ishiura, Takao Kondo, Susan S. Golden, Carl H. Johnson, and their colleagues discovered the gene cluster in 1998 and named the gene cluster kaiABC, as "kai" means “cycle” in Japanese. They generated 19 different clock mutants that were mapped to kaiA, kaiB, and kaiC genes, and successfully cloned the gene clus... | 1 | Gene expression + Signal Transduction |
While tribocorrosion phenomena may affect many materials, they are most critical for metals, especially the normally corrosion resistant so-called passive metals. The vast majority of corrosion resistant metals and alloys used in engineering (stainless steels, titanium, aluminium etc.) fall into this category. These me... | 0 | Metallurgy |
The FSP is used when metals properties want to be improved using other metals for support and improvement of the first. This is promising process for the automotive and aerospace industries where new material will need to be developed to improve resistance to wear, creep, and fatigue. (Misha) Examples of materials succ... | 0 | Metallurgy |
In 1982, Koiti Titanis lab identified an "N-terminal blocking group" on the catalytic subunit of cyclic AMP-dependent protein kinase in cows as n-tetradecanoyl. Almost simultaneously in Claude B. Klees lab, this same N-terminal blocking group was further characterized as myristic acid. Both labs made this discovery ut... | 1 | Gene expression + Signal Transduction |
Like its counterpart, RB-E2F, the DREAM complex is also affected by similar growth stimuli and subsequent cyclin-CDK activity. Increasing cyclin D-CDK4 and cyclin E-CDK2 activity dissociates the DREAM complex from the promoter by phosphorylation of p130. Hyper-phosphorylated p130 is subsequently degraded and E2F4 expo... | 1 | Gene expression + Signal Transduction |
Sinter plants agglomerate iron ore fines (dust) with other fine materials at high temperature, to create a product that can be used in a blast furnace. The final product, a sinter, is a small, irregular nodule of iron mixed with small amounts of other minerals. The process, called sintering, causes the constituent mate... | 0 | Metallurgy |
The repressor is an allosteric protein, i.e. it can assume either one of two slightly different shapes, which are in equilibrium with each other. In one form the repressor will bind to the operator DNA with high specificity, and in the other form it has lost its specificity. According to the classical model of induct... | 1 | Gene expression + Signal Transduction |
NUT carcinoma is a rare, highly aggressive malignancy. Initially, it was regarded as occurring in the midline areas of the upper respiratory tract, upper digestive tract, and mediastinum (i.e. central compartment of the thoracic cavity) of young adults and to lesser extents children and infants. It was therefore terme... | 1 | Gene expression + Signal Transduction |
Wire arc spray is a form of thermal spraying where two consumable metal wires are fed independently into the spray gun. These wires are then charged and an arc is generated between them. The heat from this arc melts the incoming wire, which is then entrained in an air jet from the gun. This entrained molten feedstock i... | 0 | Metallurgy |
miRNA-324-5p is a relatively new and understudied microRNA. It is an important regulator in several diseases, and its effects span across the body from neuronal dysregulation in seizure to hepatocellular carcinoma and cardiac disease. Because microRNAs have numerous targets, they are capable of regulating multiple path... | 1 | Gene expression + Signal Transduction |
* Railway - gearboxes, wheels, transmissions
* Machine tools - lathe gearboxes, mills
* Steel works - roll bearings, roll neck rings
* Power generation - various generator components
Due to the need to insert a core and also that to be effective, the core has to be in relatively close proximity to the bore of the p... | 0 | Metallurgy |
The role of the activators is primarily disruption and removal of the oxide layer on the metal surface (and also the molten solder), to facilitate direct contact between the molten solder and metal. The reaction product is usually soluble or at least dispersible in the molten vehicle. The activators are usually either ... | 0 | Metallurgy |
The meteorite fell to Earth after the retreat of glaciers from the area. All fragments recovered were found at the surface, partly buried, some on unstable terrain. The largest fragment was recovered in an area where the landscape consists of "flowing" gravel or clay-like sediments on permafrost, indicating that it had... | 0 | Metallurgy |
The way that porosity develops during the dealloying process has been studied computationally to understand the diffusional pathways on an atomistic level. Firstly, the less noble atoms must be dissolved away from the surface of the alloy. This process is easiest for the lower coordinated atoms, i.e., those bonded to f... | 0 | Metallurgy |
Activating Protein 2 (AP-2) is a family of closely related transcription factors which plays a critical role in regulating gene expression during early development. | 1 | Gene expression + Signal Transduction |
In many cases, gatekeeper genes encode a system of checks and balances that monitor cell division and death. When tissue damage occurs, for example, products of gatekeeper genes ensure that balance of cell growth over cellular death remains in check. In the presence of competent gatekeeper genes, mutations of other ge... | 1 | Gene expression + Signal Transduction |
Mutations in TCF4 cause Pitt-Hopkins Syndrome (PTHS). These mutations cause TCF4 proteins to not bind to DNA properly and control the differentiation of the nervous system. It has been suggested that TCF4 loss-of-function leads to decreased Wnt signaling and, consequently, a reduced neural progenitor proliferation. In ... | 1 | Gene expression + Signal Transduction |
* DUSP1, DUSP2, DUSP3, DUSP4, DUSP5, DUSP6, DUSP7, DUSP8, DUSP9
* DUSP10, DUSP11, DUSP12, DUSP13, DUSP14, DUSP15, DUSP16, DUSP18, DUSP19
* DUSP21, DUSP22, DUSP23, DUSP26, DUSP27, DUSP28 | 1 | Gene expression + Signal Transduction |
Beryllide is an intermetallic compound of beryllium with other metals, e.g. zirconium, tantalum, titanium, nickel, or cobalt. Typical chemical formulae are BeTi and FeBe. These are hard, metal-like materials that display properties distinct from the constituents, especially with regards to their resilience toward oxi... | 0 | Metallurgy |
Caustic embrittlement is the phenomenon in which the material of a boiler becomes brittle due to the accumulation of caustic substances. | 0 | Metallurgy |
C/EBPβ has been found to have a role in the development of osteoporosis. The full-length isoform of the C/EBPβ protein (LAP) activates the MafB gene, whereas the short isoform (LIP) suppresses it. MafB gene activation suppresses the formation of osteoclasts. Thus, upregulation of LAP diminishes the number of osteoclast... | 1 | Gene expression + Signal Transduction |
The phosphatome of an organism is the set of phosphatase genes in its genome. Phosphatases are enzymes that catalyze the removal of phosphate from biomolecules. Over half of all cellular proteins are modified by phosphorylation which typically controls their functions. Protein phosphorylation is controlled by the oppo... | 1 | Gene expression + Signal Transduction |
Sigma-2 receptors have been found to be highly expressed in proliferating cells, including tumor cells, and to play a role in the differentiation, morphology, and survival of those cells. By interacting with EGFR membrane proteins sigma-2 receptors play a role in the regulation of signals further downstream such as PKC... | 1 | Gene expression + Signal Transduction |
The SH2 domain of Grb2 binds to phosphorylated tyrosine-containing peptides on receptors or scaffold proteins with a preference for pY-X-N-X, where X is generally a hydrophobic residue such as valine (see [http://sh2domain.org]).
The N-terminal SH3 domain binds to proline-rich peptides and can bind to the Ras-guanine e... | 1 | Gene expression + Signal Transduction |
Vacuum induction melting (VIM) utilizes electric currents to melt metal within a vacuum. The first prototype was developed in 1920. Induction heating induces eddy currents within conductors. Eddy currents create heating effects to melt the metal. Vacuum induction melting has been used in both the aerospace and nuclea... | 0 | Metallurgy |
This pathway has a significant effect in the way genes are translated, restricting the amount of gene expression. It is still a new field in genetics, but its role in research has already led scientists to uncover numerous explanations for gene regulation. Studying nonsense-mediated decay has allowed scientists to dete... | 1 | Gene expression + Signal Transduction |
Two Soviet scientists, B. R. Lazarenko and N. I. Lazarenko, were tasked in 1943 to investigate ways of preventing the erosion of tungsten electrical contacts due to sparking. They failed in this task but found that the erosion was more precisely controlled if the electrodes were immersed in a dielectric fluid. This led... | 0 | Metallurgy |
Shrinkage defects
can occur when standard feed metal is not available to compensate for shrinkage as the thick metal solidifies. Shrinkage defects will have jagged or linear appearance. Shrinkage defects usually occur in either the cope or drag portion of the casting. Shrinkage defects can be split into two different... | 0 | Metallurgy |
Inhibition of proton pumps significantly decreases the acidity of the gastrointestinal tract, reducing the symptoms of acid-related diseases. The resulting change in pH decreases survival of the bacteria H.pylori, a major cause of peptic ulcer disease. Once the proton pump inhibitor eradicates this bacteria within the ... | 1 | Gene expression + Signal Transduction |
Brazing (sometimes known as silver soldering or hard soldering) requires a higher temperature than soft soldering (> 450 °C). As well as removing existing oxides, rapid oxidation of the metal at the elevated temperatures has to be avoided. This means that fluxes need to be more aggressive and to provide a physical barr... | 0 | Metallurgy |
Liquation is a metallurgical method for separating metals from an ore or alloy. The material must be heated until one of the metals starts to melt and drain away from the other and can be collected. This method was largely used to remove lead containing silver from copper, but it can also be used to remove antimony fro... | 0 | Metallurgy |
Alclad is a corrosion-resistant aluminium sheet formed from high-purity aluminium surface layers metallurgically bonded (rolled onto) to high-strength aluminium alloy core material. It has a melting point of about . Alclad is a trademark of Alcoa but the term is also used generically.
Since the late 1920s, Alclad has b... | 0 | Metallurgy |
For technical reasons, synaptic structure and function have been historically studied at unusually large model synapses, for example:
* Squid giant synapse
* Neuromuscular junction (NMJ), a cholinergic synapse in vertebrates, glutamatergic in insects
* Ciliary calyx in the ciliary ganglion of chicks
* Calyx of Held in ... | 1 | Gene expression + Signal Transduction |
Chemical synapses are biological junctions through which neurons' signals can be sent to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons to form circuits within the central nervous system. They are crucial to the biological computations that underlie perception a... | 1 | Gene expression + Signal Transduction |
A coating or paint is usually a fluid applied covering applied to a surface in contact with a corrosive situation such as the atmosphere. The surface is usually called the substrate. In corrosion prevention applications the purpose of applying the coating is mainly functional rather than decorative. Paints and lacquers... | 0 | Metallurgy |
Carbon dioxide () from air and bicarbonate () or carbonate () anions dissolved in water react with the calcium hydroxide (, portlandite) produced by Portland cement hydration in concrete to form calcium carbonate () while releasing a water molecule in the following reaction:
Exception made of the water molecule, the ... | 0 | Metallurgy |
Material properties such as strength, chemical reactivity, stress corrosion cracking resistance, weldability, deformation behavior, resistance to radiation damage, and magnetic susceptibility can be highly dependent on the material’s texture and related changes in microstructure. In many materials, properties are tex... | 0 | Metallurgy |
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) is a protein that in humans is encoded by the PPARGC1A gene. PPARGC1A is also known as human accelerated region 20 (HAR20). It may, therefore, have played a key role in differentiating humans from apes.
PGC-1α is the master regulator of mitoc... | 1 | Gene expression + Signal Transduction |
An intermediate stage in the process of eukaryotic RNA splicing is the formation of a lariat structure. It is anchored at an adenosine residue in intron between 10 and 50 nucleotides upstream of the 3' splice site. A short conserved sequence (the branch point sequence) functions as the recognition signal for the site o... | 1 | Gene expression + Signal Transduction |
The problem of landslides in spoil tips was first brought to public attention in October 1966 in English speaking world when a spoil tip at Aberfan in Wales gave way, killing 144 people, 116 of them children. The tip was built over a spring, increasing its instability, and its height exceeded guidelines. Water from hea... | 0 | Metallurgy |
Modulation of neurotransmitter release by G-protein-coupled receptors (GPCRs) is a prominent presynaptic mechanism for regulation of synaptic transmission. The activation of GPCRs located at the presynaptic terminal, can decrease the probability of neurotransmitter release. This presynaptic depression involves activati... | 1 | Gene expression + Signal Transduction |
According to a research study conducted Hutton, M et al, a missense mutation occurring on the 5 region of the RNA associated with the tau protein was found to be correlated with inherited dementia (known as FTDP-17). The splice-site mutations all destabilize a potential stem–loop structure which is most likely involved... | 1 | Gene expression + Signal Transduction |
Pattinson's process or pattinsonisation is a method for removing silver from lead, discovered by Hugh Lee Pattinson in 1829 and patented in 1833.
The process is dependent on the fact that lead which has least silver in it solidifies first on liquefaction, leaving the remaining liquid richer in silver.
In practice sever... | 0 | Metallurgy |
Titanium boride (TiB) is intentionally added to the melt for grain refinement to improve mechanical properties.
Phosphorus is added to the melt hypereutectic alloys for modification of the silicon phase for better mechanical properties. This creates AlP inclusions.
Boron treatment inclusions ( (Ti, V)B ) form when boro... | 0 | Metallurgy |
Precipitation in hydrometallurgy involves the chemical precipitation from aqueous solutions, either of metals and their compounds or of the contaminants. Precipitation will proceed when, through reagent addition, evaporation, pH change or temperature manipulation, the amount of a species present in the solution exceeds... | 0 | Metallurgy |
The pan amalgamation process is a method to extract silver from ore, using salt and copper(II) sulfate in addition to mercury. The process was widely used from 1609 through the 19th century; it is no longer used.
The patio process had been used to extract silver from ore since its invention in 1557. One drawback of th... | 0 | Metallurgy |
When an antigen-presenting cell interacts with a T cell receptor on T cells, there is an increase in the cytoplasmic level of calcium, which activates calcineurin by binding a regulatory subunit and activating calmodulin binding. Calcineurin induces transcription factors (NFATs) that are important in the transcription ... | 1 | Gene expression + Signal Transduction |
Histidine phosphotransfer domains and histidine phosphotransferases (both often abbreviated HPt) are protein domains involved in the "phosphorelay" form of two-component regulatory systems. These proteins possess a phosphorylatable histidine residue and are responsible for transferring a phosphoryl group from an aspart... | 1 | Gene expression + Signal Transduction |
*NDUFA2NM_002488
*NDUFA3 NM_004542
*NDUFA4 NM_002489
*NDUFA5 NM_005000
*NDUFA6 NM_002490
*NDUFA7 NM_005001 Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
*NDUFA8 NM_014222
*NDUFA9 NM_005002
*NDUFA10 NM_004544
*NDUFA11 NM_175614
*NDUFA12 NM_018838
*NDUFA13 NM_015965
*NDUFAF2 ... | 1 | Gene expression + Signal Transduction |
Rose's metal has several common uses:
#As a solder. It was used to secure cast iron railings and balusters in pockets in stone bases and steps.
#As a heat transfer medium in heating baths.
#As a malleable filling to prevent tubes and pipes from crimping when bent. Roses metal is melted and poured into the tube. It then... | 0 | Metallurgy |
Advantages cited for the IsaKidd technology include:
* long life – the operational life of the permanent cathodes without repair is said to be over seven years under correct operating conditions for electrowinning applications and over 15 years for electrorefining applications
* reduced labour costs – due to the elimi... | 0 | Metallurgy |
In recent publications, prof. Sindo Kou has proposed an approach to evaluate susceptibility to solidification cracking; this approach is based on a similar approach where a quantity, , which has the dimensions of a temperature is proposed as an index of the cracking susceptibility. Again one could exploit Scheil based ... | 0 | Metallurgy |
* 999.99—five nines fine: The purest silver ever produced. This was achieved by the Royal Silver Company of Bolivia.
* 999.9—four nines fine: ultra-fine silver used by the Royal Canadian Mint for their Silver Maple Leaf and other silver coins
* 999—fine silver or three nines fine: used in Good Delivery bullion bars and... | 0 | Metallurgy |
G stimulates the membrane-bound phospholipase C beta, which then cleaves PIP (a minor membrane phosphoinositol) into two second messengers, IP3 and diacylglycerol (DAG).
The Inositol Phospholipid Dependent Pathway is used as a signal transduction pathway for many hormones including:
* ADH (Vasopressin/AVP) – Induces th... | 1 | Gene expression + Signal Transduction |
* Hepatitis C infection
* Antisocial personality disorder
* Borderline personality traits
* Schizoid/avoidant behavior
Given that the A1+ allele is associated with antisocial personality disorder, one may infer that the allele is also associated with narcissistic personality disorder and histrionic personality disorder... | 1 | Gene expression + Signal Transduction |
Genetic regulatory circuits (also referred to as transcriptional regulatory circuits) is a concept that evolved from the Operon Model discovered by François Jacob and Jacques Monod. They are functional clusters of genes that impact each other's expression through inducible transcription factors and cis-regulatory elem... | 1 | Gene expression + Signal Transduction |
In winter conditions, or in cold climates, when the temperature falls below , the crystallization of ice in the pores of concrete is also a physical mechanism (change of state) responsible for the volumetric expansion of a substance exerting a high tensile strength inside the concrete matrix. When the tensile strength ... | 0 | Metallurgy |
The expansion of gold mining in the Rand of South Africa began to slow down in the 1880s, as the new deposits being found tended to contain pyritic ore. The gold could not be extracted from this compound with any of the then available chemical processes or technologies.
In 1887, John Stewart MacArthur, working in colla... | 0 | Metallurgy |
In the adult brain, PPs are essential for synaptic functions and are involved in the negative regulation of higher-order brain functions such as learning and memory. Dysregulation of their activity has been linked to several disorders including cognitive ageing and neurodegeneration, as well as cancer, diabetes and obe... | 1 | Gene expression + Signal Transduction |
Light microscopes are designed for placement of the specimen's polished surface on the specimen stage either upright or inverted. Each type has advantages and disadvantages. Most LOM work is done at magnifications between 50 and 1000X. However, with a good microscope, it is possible to perform examination at higher mag... | 0 | Metallurgy |
FSP has benefits for when two materials' would be needed to be mixed. “FSP is a short route, solid state processing technique with one-step processing that achieves microstructural refinement densification and homogeneity” (Ma) FSW helps modify materials so that metaling down or changing the material drastically does n... | 0 | Metallurgy |
The model represents individuals as networks of interacting transcriptional regulators. Each individual expresses genes encoding transcription factors. The product of each gene can regulate the expression level of itself and/or the other genes through cis-regulatory elements. The interactions among genes constitute a... | 1 | Gene expression + Signal Transduction |
The outbreak of hostilities in eastern Ukraine in 2014 complicated the activities of the enterprise. As a result, the plant ended 2014 with a net loss of UAH 4,871.533 million. In the first nine months of 2015, the plant produced 426 thousand tons of pig iron and 1.664 million tons of grade K coal concentrate, but loss... | 0 | Metallurgy |
Thermal spraying need not be a dangerous process if the equipment is treated with care and correct spraying practices are followed. As with any industrial process, there are a number of hazards of which the operator should be aware and against which specific precautions should be taken. Ideally, equipment should be ope... | 0 | Metallurgy |
Metal smiths demonstrated increasing technical sophistication, producing both utilitarian and status-linked items. During the latter phase, Michoacán emerged as a technological hub, with metal artifacts also appearing at the adjacent zones of Guerrero and Jalisco.
Alloys became more prevalent during the second phase, ... | 0 | Metallurgy |
Platinum-samarium is a binary inorganic compound of platinum and samarium with the chemical formula PtSm. This intermetallic compound forms crystals. | 0 | Metallurgy |
In heap leaching processes, crushed (and sometimes agglomerated) ore is piled in a heap which is lined with an impervious layer. Leach solution is sprayed over the top of the heap, and allowed to percolate downward through the heap. The heap design usually incorporates collection sumps, which allow the "pregnant" leach... | 0 | Metallurgy |
Pyrometallurgy involves high temperature processes where chemical reactions take place among gases, solids, and molten materials. Solids containing valuable metals are treated to form intermediate compounds for further processing or converted into their elemental or metallic state. Pyrometallurgical processes that in... | 0 | Metallurgy |
The following example illustrates how a Boolean network can model a GRN together with its gene products (the outputs) and the substances from the environment that affect it (the inputs). Stuart Kauffman was amongst the first biologists to use the metaphor of Boolean networks to model genetic regulatory networks.
# Each... | 1 | Gene expression + Signal Transduction |
HIV, the retrovirus that causes AIDS in humans, produces a single primary RNA transcript, which is alternatively spliced in multiple ways to produce over 40 different mRNAs. Equilibrium among differentially spliced transcripts provides multiple mRNAs encoding different products that are required for viral multiplicatio... | 1 | Gene expression + Signal Transduction |
In its earliest forms, most hardware was simple and hand-made – usually of readily available materials such as wood or leather. A patch of leather spanning between the stile and jamb and fastened with wooden pegs served to hinge a door or shutter. Hand-carved wooden hinges and pintles, slide bolts and lift-latches were... | 0 | Metallurgy |
A partially coherent interphase boundary is an intermediate type of IPB that lies between the completely coherent and non-coherent IPBs. In this type of boundary, there is a partial match between the atomic arrangements of the particle and the matrix, but not a perfect match. As a result, coherency strains are partiall... | 0 | Metallurgy |
Copperas works are manufactories where copperas (iron(II) sulfate) is produced from pyrite, often obtained as a byproduct during coal mining, and iron. The history of producing green vitriol, as it was known, goes back hundreds of years in Scotland. In 1814 the wool-producing city of Steubenville, Ohio had seven copper... | 0 | Metallurgy |
Scrubbers are material washers used to break down and disperse clays in order to prepare mineral ores or construction aggregates for further processing. Sepro Tyre Drive Scrubbers are manufactured up to 3.6m in diameter and are capable of processing up to 1500 tonnes per hour of material. Shell supported Scrubbers such... | 0 | Metallurgy |
Gas phase coating is carried out at higher temperatures, about 1080 °C. The coating material is usually loaded onto trays without physical contact with the parts to be coated. The coating mixture contains active coating material and activator, but usually not thermal ballast. As in the pack cementation process, gaseous... | 0 | Metallurgy |
* [https://www.wikidata.org/wiki/Q101294270 Васина Т. А.] Формирование горнозаводских округов в конце XVIII — первой половине XIX веков на территории современной Удмуртии // Научный диалог — 2019. — вып. 7. — С. 222—239. — ISSN 2227-1295 — [https://www.nauka-dialog.ru/jour/article/view/1254 doi:10.24224/2227-1295-2019-... | 0 | Metallurgy |
Eukaryotic RNA must undergo a series of modifications in order to be exported from the nucleus and successfully translated into function proteins, many of which are dependent on mRNA capping, the first mRNA modification to take place. 5 capping is essential for mRNA stability, enhancing mRNA processing, mRNA export an... | 1 | Gene expression + Signal Transduction |
When replicating its (+)ssRNA genome, the poliovirus RdRp is able to carry out recombination. Recombination appears to occur by a copy choice mechanism in which the RdRp switches (+)ssRNA templates during negative strand synthesis. Recombination frequency is determined in part by the fidelity of RdRp replication. ... | 1 | Gene expression + Signal Transduction |
*RPL5
*RPL8
*RPL9
*RPL10A
*RPL11
*RPL14
*RPL25
*RPL26L1
*RPL27
*RPL30
*RPL32
*RPL34
*RPL35
*RPL35A
*RPL36AL
*RPS5
*RPS6
*RPS6KA3
*RPS6KB1
*RPS6KB2
*RPS13
RPS19BP1
*RPS20
*RPS23
*RPS24
*RPS27 transcribed with ubiquitin (see FAU (gene))
*RPN1 Ribophorin anchors the ribosome to rough endoplasmic reticulum | 1 | Gene expression + Signal Transduction |
In nerve terminals, synaptic vesicles are produced quickly to compensate for their rapid depletion during neurotransmitter release. Their biogenesis involves segregating synaptic vesicle membrane proteins from other cellular proteins and packaging those distinct proteins into vesicles of appropriate size. Besides, it e... | 1 | Gene expression + Signal Transduction |
Thermal barrier coatings (TBCs) are used extensively in gas turbine engines to increase component life and engine performance. A coating of about 1-200 µm can reduce the temperature at the superalloy surface by up to 200 K. TBCs are a system of coatings consisting of a bond coat, a thermally grown oxide (TGO), and a th... | 0 | Metallurgy |
Chemical messengers bind to metabotropic receptors to initiate a diversity of effects caused by biochemical signaling cascades. G protein-coupled receptors are all metabotropic receptors. When a ligand binds to a G protein-coupled receptor, a guanine nucleotide-binding protein, or G protein, activates a second messenge... | 1 | Gene expression + Signal Transduction |
The release of neurotransmitter is accomplished by the fusion of neurotransmitter vesicles to the presynaptic membrane. Although the details of this mechanism are still being studied there is a consensus on some details of the process. Synaptic vesicle fusion with the presynaptic membrane is known to require a local ... | 1 | Gene expression + Signal Transduction |
The bioluminescent bacterium A. fischeri is the first organism in which QS was observed. It lives as a mutualistic symbiont in the photophore (or light-producing organ) of the Hawaiian bobtail squid. When A. fischeri cells are free-living (or planktonic), the autoinducer is at low concentration, and, thus, cells do not... | 1 | Gene expression + Signal Transduction |
The Dunaverney (1050–910 BC) and Little Thetford (1000–701 BC) flesh-hooks have been shown to be made using a lost-wax process. The Little Thetford flesh-hook, in particular, employed distinctly inventive construction methods. The intricate Gloucester Candlestick (1104–1113 AD) was made as a single-piece wax model, the... | 0 | Metallurgy |
The core of the signal peptide contains a long stretch of hydrophobic amino acids (about 5–16 residues long) that has a tendency to form a single alpha-helix and is also referred to as the "h-region". In addition, many signal peptides begin with a short positively charged stretch of amino acids, which may help to enfor... | 1 | Gene expression + Signal Transduction |
The introduction of atom into a crystal of atom creates a pinning point for multiple reasons. An alloying atom is by nature a point defect, thus it must create a stress field when placed into a foreign crystallographic position, which could block the passage of a dislocation. However, it is possible that the alloying m... | 0 | Metallurgy |
MIM signed the first ISASMELT licence agreement with Agip Australia Proprietary Limited ("Agip") in July 1990. Agip, a subsidiary of the Italian oil company ENI, was developing the Radio Hill nickel-copper deposit near Karratha in Western Australia. MIM and representatives of Agip conducted a series of trials in which ... | 0 | Metallurgy |
Degrading concrete has been the focus of many studies and the most obvious sign is calcium-rich leachate seeping from a concrete structure.
Calthemite stalactites can form on concrete structures and "artificial caves" lined with concrete (e.g. mines and tunnels) significantly faster than those in limestone, marble or d... | 0 | Metallurgy |
The replication of technique in copper production includes a vast number of possibilities in trying to recreate what has been found through archaeological excavation. Tylecote and Boydell have experimented on possible explanations for the levels of iron found in certain copper objects and the possibility of removing ex... | 0 | Metallurgy |
This class is defined by loss of two beta-strands and additional N-terminal strands. Both namesakes of this superfamily, myosin and kinesin, have shifted to use ATP. | 1 | Gene expression + Signal Transduction |
Trommel screens have a rotating drum on a shallow angle with screen panels around the diameter of the drum. The feed material always sits at the bottom of the drum and, as the drum rotates, always comes into contact with clean screen. The oversize travels to the end of the drum as it does not pass through the screen, w... | 0 | Metallurgy |
The lactose operon (lac operon) is an operon required for the transport and metabolism of lactose in E. coli and many other enteric bacteria. Although glucose is the preferred carbon source for most enteric bacteria, the lac operon allows for the effective digestion of lactose when glucose is not available through the ... | 1 | Gene expression + Signal Transduction |
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