text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
in yellow and sulfur we found eight carotenoids and beta-carotene , in old-gold eight carotenoids and four carotenes . | NA | {
"id": "C0053396",
"name": "beta-carotene",
"pos": [
52,
65
]
} | {
"id": "C0007271",
"name": "carotenoids",
"pos": [
86,
97
]
} |
[ action of deoxyuridine on the inhibition of the rhizogenesis and the hypocotyl growth observed in the presence of 5-bromodeoxyuridine in the cuttings of etiolated tomato seedlings ] . | NA | {
"id": "C0011535",
"name": "deoxyuridine",
"pos": [
12,
24
]
} | {
"id": "C0006233",
"name": "bromodeoxyuridine",
"pos": [
118,
135
]
} |
the nucleic acid content of cultured root cells was shown to be only 20 % and 27 % of the rna and dna respectively found in attached roots . | NA | {
"id": "C0028606",
"name": "nucleic acid",
"pos": [
4,
16
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
98,
101
]
} |
several growth substances ( iaa , alpha-naa ) are able to reduce thermal stability of artificially reconstituted nucleoproteins without splitting off measurable amounts of protein from dna . | NA | {
"id": "C0028612",
"name": "nucleoproteins",
"pos": [
113,
127
]
} | {
"id": "C0033684",
"name": "protein",
"pos": [
172,
179
]
} |
1:0,5 : 0,5 ) exhibited different thermal stability depending on whether part of the histones or residual nuclear proteins were first bound to dna . | NA | {
"id": "C0019652",
"name": "histones",
"pos": [
85,
93
]
} | {
"id": "C0028589",
"name": "nuclear",
"pos": [
106,
113
]
} |
this phenomenon was attributed to a direct deepoxidation of diadinoxanthin on the basis of experiments with ( 14 ) c-diadinoxanthin showing a transformation of the pigment into zeaxanthin and some other euglena carotenoids , e.g . neoxanthin and beta-carotene . | NA | {
"id": "C0007271",
"name": "carotenoids",
"pos": [
211,
222
]
} | {
"id": "C0053396",
"name": "beta-carotene",
"pos": [
246,
259
]
} |
when mustard amylases were incubated with starch the pattern of products was similar to that produced by commercially available barley beta-amylase and not similar to that produced by bacillus subtilis alpha-amylase . | NA | {
"id": "C0002712",
"name": "amylases",
"pos": [
13,
21
]
} | {
"id": "C0005194",
"name": "beta-amylase",
"pos": [
135,
147
]
} |
influx of anions ( 5x10 ( -4 ) m cl ( - ) or so4 ( 2- ) ) across the plasmalemma , atp levels and co2 fixation in limnophila and chara have been measured in a comparative study.in limnophila , influx , atp level and co2 fixation were progressively reduced by increasing concentrations of carbonyl cyanide m-chlorophenylhydrazone ( cccp ) in the light ( 4000 lux ) as well as in the dark . | NA | {
"id": "C0003075",
"name": "anions",
"pos": [
10,
16
]
} | {
"id": "C0010505",
"name": "cyanide",
"pos": [
297,
304
]
} |
the inhibition induced by 5-bromouracil can not be reversed by thymine , deoxythymidine , uracil , uidine or beta-alanine , a catabolic product of uracil . | NA | {
"id": "C0006242",
"name": "bromouracil",
"pos": [
28,
39
]
} | {
"id": "C0041917",
"name": "uracil",
"pos": [
147,
153
]
} |
the inhibition induced by 5-bromouracil can not be reversed by thymine , deoxythymidine , uracil , uidine or beta-alanine , a catabolic product of uracil . | NA | {
"id": "C0040087",
"name": "thymine",
"pos": [
63,
70
]
} | {
"id": "C0041917",
"name": "uracil",
"pos": [
147,
153
]
} |
resolution of conflicting data concerning the effects of l-epinephrine and l-norepinephrine on blood pressure and heart rate of unanesthetized dogs . | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
59,
70
]
} | {
"id": "C0028351",
"name": "l-norepinephrine",
"pos": [
75,
91
]
} |
urinary excretion of 17-hydroxy-corticosteroids and 17-ketosteroids in healthy subjects , in relation to sex , age , body weight and height . | NA | {
"id": "C0001617",
"name": "corticosteroids",
"pos": [
32,
47
]
} | {
"id": "C0000167",
"name": "17-ketosteroids",
"pos": [
52,
67
]
} |
tetracycline concentrations in blood serum , bile , and prostatic and spinal fluids following oral administration of tetracycline phosphate complex and tetracycline hydrochloride . | NA | {
"id": "C0039644",
"name": "tetracycline",
"pos": [
0,
12
]
} | {
"id": "C0546879",
"name": "tetracycline hydrochloride",
"pos": [
152,
178
]
} |
blood concentrations following oral administration of chlortetracycline hydrochloride and chlortetracycline base , with and without sodium hexametaphosphate . | NA | {
"id": "C0085855",
"name": "chlortetracycline",
"pos": [
54,
71
]
} | {
"id": "C0008293",
"name": "chlortetracycline",
"pos": [
90,
107
]
} |
[ occupational lung diseases except silicosis . ii . occupational asthma ; occupational asthma caused by contact with molds ; 24 case reports ] . | NA | {
"id": "C0004096",
"name": "asthma",
"pos": [
66,
72
]
} | {
"id": "C0264423",
"name": "occupational asthma",
"pos": [
75,
94
]
} |
[ the problem of the peutz-jeghers syndrome ; observations on small-spot pigmentation of the lip mucosa , palms & foot soles in combination with intestinal polyposis in japanese ] . | NA | {
"id": "C0031269",
"name": "peutz-jeghers syndrome",
"pos": [
21,
43
]
} | {
"id": "C1257915",
"name": "intestinal polyposis",
"pos": [
145,
165
]
} |
glutamic acid , aspartic acid , alpha-alanine , proline , and hydroxyproline were found to be inhibitory in this test system . | NA | {
"id": "C0033382",
"name": "proline",
"pos": [
48,
55
]
} | {
"id": "C0020388",
"name": "hydroxyproline",
"pos": [
62,
76
]
} |
however , it is apparent that there is an intracellular accumulation of inorganic sulfate by the chondroitin-forming cells prior to the time they produce sufficient chondroitin sulfate to be demonstrable histochemically . | NA | {
"id": "C0008454",
"name": "chondroitin",
"pos": [
97,
108
]
} | {
"id": "C0008466",
"name": "chondroitin",
"pos": [
165,
176
]
} |
as an alternative hypothesis , it is suggested that iron or other heavy metals are present in the chromosomes and that cyanide and other heavy metal complexing agents produce chromosome aberrations by reacting with these metals . | NA | {
"id": "C0302583",
"name": "iron",
"pos": [
52,
56
]
} | {
"id": "C0347988",
"name": "heavy metals",
"pos": [
66,
78
]
} |
instead it is suggested that the cyanide effect may be due to a complex formation between the active agents and heavy metals , presumably iron , within the chromosomes . | NA | {
"id": "C0347988",
"name": "heavy",
"pos": [
112,
117
]
} | {
"id": "C0302583",
"name": "iron",
"pos": [
138,
142
]
} |
early effects of fasting and of carbohydrate ingestion on lipids and lipoproteins of serum in man . | NA | {
"id": "C0023779",
"name": "lipids",
"pos": [
58,
64
]
} | {
"id": "C0023820",
"name": "lipoproteins",
"pos": [
69,
81
]
} |
the methods previously developed whereby single cells plated in petri dishes grow into isolated macroscopic colonies can successfully be applied to the plating of human fibroblastic stocks . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
48,
53
]
} | {
"id": "C0016030",
"name": "fibroblastic",
"pos": [
169,
181
]
} |
fibroblastic cells are also more resistant to tryptic digestion of the bond uniting the cells to glass surfaces . | NA | {
"id": "C0016030",
"name": "fibroblastic cells",
"pos": [
0,
18
]
} | {
"id": "C0007634",
"name": "the cells",
"pos": [
84,
93
]
} |
by use of differential media , growth of both fibroblastic and epithelioid cells , respectively , has been obtained , from dispersed single cells obtained by trypsinization of a specimen of human embryonic lung . | NA | {
"id": "C0016030",
"name": "fibroblastic",
"pos": [
46,
58
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
140,
145
]
} |
the assay of histamine , 5-hydroxytryptamine , adrenaline , and noradrenaline , on the blood pressure of the fowl . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
47,
57
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
64,
77
]
} |
[ clinical and roentgenological picture of pulmonary echinococcosis and differential diagnosis of echinococcosis from pulmonary tuberculosis ] . | NA | {
"id": "C0013505",
"name": "pulmonary echinococcosis",
"pos": [
43,
67
]
} | {
"id": "C0013502",
"name": "echinococcosis",
"pos": [
98,
112
]
} |
[ gout & rheumatoid arthritis ; 393 determinations of uric acid in blood in 35 cases of gout ] . | NA | {
"id": "C0003868",
"name": "gout",
"pos": [
2,
6
]
} | {
"id": "C0018099",
"name": "gout",
"pos": [
88,
92
]
} |
some differences between the actions of salivary kallikrein and trypsin in releasing kallidin or bradykinin have been observed , and some modifications of previous methods of preparing crude kallidin and bradykinin are suggested . | NA | {
"id": "C0022474",
"name": "kallidin",
"pos": [
85,
93
]
} | {
"id": "C0006100",
"name": "bradykinin",
"pos": [
204,
214
]
} |
chemical and pharmacological tests failed to differentiate between kallidin and bradykinin which must be , therefore , closely similar compounds . | NA | {
"id": "C0022474",
"name": "kallidin",
"pos": [
67,
75
]
} | {
"id": "C0006100",
"name": "bradykinin",
"pos": [
80,
90
]
} |
amongst the compounds which , when injected subcutaneously in substantial amount shortly before the chloral hydrate ( 250 mg./kg . intraperitoneally ) , increased sleeping time significantly were adrenaline , noradrenaline , phenylephrine , methoxamine , 5-hydroxytryptamine ( serotonin ) , histamine , ergotamine , yohimbine , and atropine . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
196,
206
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
209,
222
]
} |
[ nitrosoamines of secondary amines . ii . polarographic method for the determination of proline and hydroxyproline in protein hydrolysates ] . | NA | {
"id": "C0033382",
"name": "proline",
"pos": [
89,
96
]
} | {
"id": "C0020388",
"name": "hydroxyproline",
"pos": [
101,
115
]
} |
a study of the quantitative relationship between antidiuretic hormone ( vasopressin ) and the renal tubular reabsorption of water . | NA | {
"id": "C0042413",
"name": "antidiuretic hormone",
"pos": [
49,
69
]
} | {
"id": "C0003779",
"name": "vasopressin",
"pos": [
72,
83
]
} |
probably it was the protein portion of alpha lipoprotein dissociated from the lipide during ultracentrifugation . | NA | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
45,
56
]
} | {
"id": "C0023779",
"name": "lipide",
"pos": [
78,
84
]
} |
the distribution of gold following the injection of obesity-inducing doses of aurothioglucose in the mouse . | NA | {
"id": "C0018026",
"name": "gold",
"pos": [
20,
24
]
} | {
"id": "C0018033",
"name": "aurothioglucose",
"pos": [
78,
93
]
} |
[ adrenalin and noradrenalin content of adrenal blood in dogs submitted to one or more nicotine injections ] . | NA | {
"id": "C0014563",
"name": "adrenalin",
"pos": [
2,
11
]
} | {
"id": "C0028351",
"name": "noradrenalin",
"pos": [
16,
28
]
} |
[ action of hydrocyanic acid poisoning on the hypertensive effects of adrenalin and noradrenalin in dogs without bone marrow ] . | NA | {
"id": "C0014563",
"name": "adrenalin",
"pos": [
70,
79
]
} | {
"id": "C0028351",
"name": "noradrenalin",
"pos": [
84,
96
]
} |
[ chemodectoma ( non-chromaffin paraganglioma ) of the carotid body ; histogenesis & definition according to the most recent advances on tumors of the chemoreceptors ] . | NA | {
"id": "C0007279",
"name": "chemodectoma",
"pos": [
2,
14
]
} | {
"id": "C0030422",
"name": "non-chromaffin paraganglioma",
"pos": [
17,
45
]
} |
[ comparative study of penicillin in blood after administration , in equal doses , of oral penicillin v & intramuscular penicillin g ] . | NA | {
"id": "C0030842",
"name": "penicillin",
"pos": [
23,
33
]
} | {
"id": "C0030840",
"name": "penicillin v",
"pos": [
91,
103
]
} |
[ first results of studies on the behavior of hormonal metabolites in leukemia ; urinary excretion of 17-ketosteroids & reducing keto-corticoids ] . | NA | {
"id": "C0000167",
"name": "17-ketosteroids",
"pos": [
102,
117
]
} | {
"id": "C0001617",
"name": "corticoids",
"pos": [
134,
144
]
} |
[ a 3-day depot with dbed-penicillin v as a basis for oral therapy with penicillin v ] . | NA | {
"id": "C0030842",
"name": "penicillin",
"pos": [
26,
36
]
} | {
"id": "C0030840",
"name": "penicillin v",
"pos": [
72,
84
]
} |
adynamia episodica hereditaria : a disease clinically resembling familial periodic paralysis but characterized by increasing serum potassium during the paralytic attacks . | NA | {
"id": "C0238357",
"name": "adynamia episodica hereditaria",
"pos": [
0,
30
]
} | {
"id": "C0030443",
"name": "familial",
"pos": [
65,
73
]
} |
[ effects of adrenalin and noradrenalin on the cerebral circulation ; registration of the intracranial venous pressure of the dog by way of the external jugular vein ] . | NA | {
"id": "C0014563",
"name": "adrenalin",
"pos": [
13,
22
]
} | {
"id": "C0028351",
"name": "noradrenalin",
"pos": [
27,
39
]
} |
blood pressure reversal by 1-norepinephrine and 1-epinephrine in rats adrenergically blocked and treated with acth . | NA | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
29,
43
]
} | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
50,
61
]
} |
the administration of choline 2:6-xylyl ether bromide ( tm 10 ) daily to rats for two weeks depletes the suprarenals of about one-half their normal content of adrenaline and noradrenaline . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
159,
169
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
174,
187
]
} |
the imidazolepropionyl ester was metabolized by cholinesterases obtained from human plasma , ox spleen , ox serum , and guinea-pig liver , but not by rat liver or bovine red cell cholinesterase . | NA | {
"id": "C0008429",
"name": "cholinesterases",
"pos": [
48,
63
]
} | {
"id": "C0001044",
"name": "red cell cholinesterase",
"pos": [
170,
193
]
} |
[ comparative study on the activities of phosphotransferase and phytase of certain phosphatase preparations from grains ] . | NA | {
"id": "C0031853",
"name": "certain",
"pos": [
75,
82
]
} | {
"id": "C0031678",
"name": "phosphatase",
"pos": [
83,
94
]
} |
[ degradation of human serum albumin by rabbit spleen extracts . iv . individual variations in the reaction of anti-albumin serum of rabbits with degraded albumin ] . | NA | {
"id": "C0304925",
"name": "human serum albumin",
"pos": [
17,
36
]
} | {
"id": "C0001924",
"name": "albumin",
"pos": [
155,
162
]
} |
the most common symptoms , in order of frequency , were hemorrhage from the bowel , intestinal obstruction , acute diverticulitis , and intussusception . | NA | {
"id": "C0021843",
"name": "intestinal obstruction",
"pos": [
84,
106
]
} | {
"id": "C0021933",
"name": "intussusception",
"pos": [
136,
151
]
} |
the measurement of the rate of blood flow in the calf and paw of dogs by the venous occlusion plethysmograph technique with a note on the effects of intravenous adrenaline and noradrenaline . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
161,
171
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
176,
189
]
} |
these data , and observations on the effect of pre-incubation of kidney slices in s ( 35 ) -free media before the addition of radiosulfate , have been interpreted as evidence that s ( 35 ) accumulation in vitro may be resolved into at least two processes , namely ( a ) entrance of the isotope-labelled anion into the cells , by diffusion and/or active transport , and ( b ) complexing of s ( 35 ) ( in ionic or other form ) with an intracellular component . | NA | {
"id": "C0003075",
"name": "anion",
"pos": [
303,
308
]
} | {
"id": "C0022023",
"name": "ionic",
"pos": [
403,
408
]
} |
the requirement for serine is less specific than that of the other 13 amino acids and it is partially replaced by glycine , or alanine , or by several combinations of so called accessory amino acids . | NA | {
"id": "C0017890",
"name": "glycine",
"pos": [
114,
121
]
} | {
"id": "C0002520",
"name": "amino acids",
"pos": [
187,
198
]
} |
the requirement for serine is less specific than that of the other 13 amino acids and it is partially replaced by glycine , or alanine , or by several combinations of so called accessory amino acids . | NA | {
"id": "C0001898",
"name": "alanine",
"pos": [
127,
134
]
} | {
"id": "C0002520",
"name": "amino acids",
"pos": [
187,
198
]
} |
the rate of movement of the k can be related to the electrochemical activity of the ion , the lability of the sites on which it is absorbed , and cation + anion pair diffusion within the cell . | NA | {
"id": "C0022023",
"name": "ion",
"pos": [
84,
87
]
} | {
"id": "C0007447",
"name": "cation",
"pos": [
146,
152
]
} |
the rate of movement of the k can be related to the electrochemical activity of the ion , the lability of the sites on which it is absorbed , and cation + anion pair diffusion within the cell . | NA | {
"id": "C0022023",
"name": "ion",
"pos": [
84,
87
]
} | {
"id": "C0003075",
"name": "anion",
"pos": [
155,
160
]
} |
radioautographic demonstration of noradrenaline and adrenaline in the adrenal medulla with i131-labelled iodate and iodate-formalin . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
34,
47
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
52,
62
]
} |
intestinal obstruction caused by spontaneous rupture of the ileum , with volvulus due to abscess formation ; | NA | {
"id": "C0021843",
"name": "intestinal obstruction",
"pos": [
0,
22
]
} | {
"id": "C0042961",
"name": "volvulus",
"pos": [
73,
81
]
} |
the antiprogesterone steroid ru-486 does not impair gonadotropin-stimulated luteal adenylyl cyclase activity or gonadotropin release by pituitary cells . | NA | {
"id": "C0018061",
"name": "gonadotropin",
"pos": [
52,
64
]
} | {
"id": "C0018066",
"name": "gonadotropin",
"pos": [
112,
124
]
} |
the antifungal imidazoles , ketoconazole and miconazole , were tested for effects on 25-hydroxyvitamin d3 metabolism in primary cultures of chick kidney cells . | NA | {
"id": "C0020924",
"name": "imidazoles",
"pos": [
15,
25
]
} | {
"id": "C0025942",
"name": "miconazole",
"pos": [
45,
55
]
} |
the effects of several cardiotonic agents ( arl-115 , amrinone , rmi 82-249 , milrinone , ci-914 , ro 13-6438 and app 201-533 ) were compared with those of ouabain on pig isolated coronary artery , guinea-pig isolated atria and guinea-pig perfused heart to compare vasodilatory and inotropic responses . | NA | {
"id": "C0002697",
"name": "amrinone",
"pos": [
54,
62
]
} | {
"id": "C0128513",
"name": "milrinone",
"pos": [
78,
87
]
} |
hydergine ( co-dergocrine , ergoloid mesylates , dihydroergotoxine ) is an ergot preparation which has been shown to be of value in the treatment of senile mental impairment . | NA | {
"id": "C0012294",
"name": "dihydroergotoxine",
"pos": [
49,
66
]
} | {
"id": "C0304712",
"name": "ergot",
"pos": [
75,
80
]
} |
besides glycine , only the basic amino acids histidine , lysine and arginine gave products with strong fluorescence . | NA | {
"id": "C0301714",
"name": "basic amino acids",
"pos": [
27,
44
]
} | {
"id": "C0024337",
"name": "lysine",
"pos": [
57,
63
]
} |
besides glycine , only the basic amino acids histidine , lysine and arginine gave products with strong fluorescence . | NA | {
"id": "C0301714",
"name": "basic amino acids",
"pos": [
27,
44
]
} | {
"id": "C0003765",
"name": "arginine",
"pos": [
68,
76
]
} |
we suggest that malondialdehyde association with plasma lipoproteins alters the lipid structure via apoprotein or apoprotein/lipid associations . | NA | {
"id": "C0023820",
"name": "lipoproteins",
"pos": [
56,
68
]
} | {
"id": "C0023779",
"name": "lipid",
"pos": [
125,
130
]
} |
verticillium agaricinum when grown for 60 min under near-uv irradiation ( 366 nm ) followed by 24 h in darkness produced maximal activity of a number of nucleic acid enzymes ( dnase i , endonuclease , nuclease , rnase a , and rnase t1 ) . | NA | {
"id": "C0014241",
"name": "rnase",
"pos": [
212,
217
]
} | {
"id": "C0018364",
"name": "rnase t1",
"pos": [
226,
234
]
} |
by using a selective medium ( propionate-rifampicin-gentamicin-colimycin-polymyxin medium ) devised for c. ramosum , analysis of the population level of this organism was performed to determine its ecology in the human intestinal tract . | NA | {
"id": "C0009316",
"name": "colimycin",
"pos": [
63,
72
]
} | {
"id": "C0032539",
"name": "polymyxin",
"pos": [
73,
82
]
} |
their activities were almost the same as those of naturally obtained lipid a , but were lower than that of bacterial lipopolysaccharide ( lps ) . | NA | {
"id": "C0023767",
"name": "lipid a",
"pos": [
69,
76
]
} | {
"id": "C0023810",
"name": "lipopolysaccharide",
"pos": [
117,
135
]
} |
inhibition of 125ipin binding by isoprenaline , adrenaline , noradrenaline and salbutamol was determined under conditions designed to produce high and low affinity agonist binding . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
48,
58
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
61,
74
]
} |
kd-values and binding site concentrations , for the interaction of human and bovine beta-casomorphins with opioid receptors in rat brain homogenates were determined in inhibition experiments , using [ 3h ] - ( d-ala2 , mephe4 , gly-ol5 ) enkephalin , [ 3h ] - ( d-ala2 , d-leu5 ) enkephalin and [ 3h ] ethylketazocin as mu- , delta- and kappa-opioid receptor ligands . | NA | {
"id": "C0034801",
"name": "opioid receptors",
"pos": [
107,
123
]
} | {
"id": "C0064239",
"name": "kappa-opioid",
"pos": [
337,
349
]
} |
the opioid activity of a series of fluorescent derivatives of oxymorphone , naloxone and naltrexone , were characterized on the electrically stimulated guinea-pig myenteric plexus-longitudinal muscle preparation . | NA | {
"id": "C0027358",
"name": "naloxone",
"pos": [
76,
84
]
} | {
"id": "C0027360",
"name": "naltrexone",
"pos": [
89,
99
]
} |
the distribution of binding sites for the neuropeptide neurotensin was studied in the hippocampal region of the rat , monkey and human brain by using the method of in vitro receptor autoradiography . | NA | {
"id": "C0027895",
"name": "neuropeptide",
"pos": [
42,
54
]
} | {
"id": "C0027930",
"name": "neurotensin",
"pos": [
55,
66
]
} |
in the anterior lobe , high molecular weight precursors of beta-endorphin ( pro-opiomelanocortin and beta-lipotropin ) were present in prepubertal ( 28 days old ) rats , but little authentic beta-endorphin was detected . | NA | {
"id": "C0033195",
"name": "pro-opiomelanocortin",
"pos": [
76,
96
]
} | {
"id": "C0023832",
"name": "beta-lipotropin",
"pos": [
101,
116
]
} |
arterial plasma concentrations of unconjugated ( i.e . free ) , sulfoconjugated and glucuronoconjugated forms of the cas dopamine ( da ) , noradrenaline ( na ) and adrenaline ( ad ) in cannulated , anesthetized , control rats remained stable during the 4.5 h long experiments . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
139,
152
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
164,
174
]
} |
subsequently , free da , na and ad increased , followed by delayed increases in conjugated ca levels . | NA | {
"id": "C0028351",
"name": "na",
"pos": [
25,
27
]
} | {
"id": "C0014563",
"name": "ad",
"pos": [
32,
34
]
} |
fnrs depleted of complement by treatment with zymosan a or of factor b by heating at 50 degrees c for 20 min , failed to promote cell adherence to the parasite . | NA | {
"id": "C0009498",
"name": "complement",
"pos": [
17,
27
]
} | {
"id": "C0033453",
"name": "factor b",
"pos": [
62,
70
]
} |
absorption of antigerm antisera by the glycoproteins of either the human serum or aorta suggested that a glycoprotein or some fragment of it acted as a target-antigen or target-epitope for the investigated antibodies and that these antibodies might attack human arterial tissue . | NA | {
"id": "C0020960",
"name": "antisera",
"pos": [
23,
31
]
} | {
"id": "C0003241",
"name": "antibodies",
"pos": [
232,
242
]
} |
absorption of antigerm antisera by the glycoproteins of either the human serum or aorta suggested that a glycoprotein or some fragment of it acted as a target-antigen or target-epitope for the investigated antibodies and that these antibodies might attack human arterial tissue . | NA | {
"id": "C0003320",
"name": "antigen",
"pos": [
159,
166
]
} | {
"id": "C0003316",
"name": "epitope",
"pos": [
177,
184
]
} |
the effects of anaesthesia inducing benzodiazepines ( diazepam , flunitrazepam , midazolam ) on serum cortisol level , blood pressure and pulse rate were examined in patients undergoing elective hysterectomy . | NA | {
"id": "C0005064",
"name": "benzodiazepines",
"pos": [
36,
51
]
} | {
"id": "C0026056",
"name": "midazolam",
"pos": [
81,
90
]
} |
in the period 1963-82 among the patients with aspecific inflammatory bowel disease , the incidence of ulcerative colitis was 3.1 per 100 000 per year , while the frequency of crohn 's disease has doubled during the observation period and now its incidence is 0.58 per 100 000 per year . | NA | {
"id": "C0021390",
"name": "inflammatory bowel",
"pos": [
56,
74
]
} | {
"id": "C0010346",
"name": "crohn 's disease",
"pos": [
175,
191
]
} |
substitution of low molecular weight heparin ( choay laboratory , cy 222 , pm 4 500 , 25 000 u anti-xa/ml ) for unfractionated heparin resulted in a progressive normalisation of the platelet count and improvement of the venous thrombosis . | NA | {
"id": "C0019139",
"name": "anti-xa",
"pos": [
95,
102
]
} | {
"id": "C0019134",
"name": "unfractionated heparin",
"pos": [
112,
134
]
} |
distant ischemia was distinguished from periinfarctional ischemia by the presence of transient thallium defects in , or slow thallium washout from , myocardium not supplied by the infarct-related coronary artery . | NA | {
"id": "C0022116",
"name": "ischemia",
"pos": [
8,
16
]
} | {
"id": "C0021308",
"name": "infarct",
"pos": [
180,
187
]
} |
the occurrence of distant ischemia was found to be dependent on the severity of stenosis in non-infarct coronary vessels . | NA | {
"id": "C0022116",
"name": "ischemia",
"pos": [
26,
34
]
} | {
"id": "C0021308",
"name": "infarct",
"pos": [
96,
103
]
} |
twelve ( 86 % ) of 14 patients with non-infarct stenosis of 75 % or greater had distant ischemia , but only 1 ( 4 % ) of 27 patients with non-infarct stenosis of less than 75 % . | NA | {
"id": "C0022116",
"name": "ischemia",
"pos": [
88,
96
]
} | {
"id": "C0021308",
"name": "infarct",
"pos": [
142,
149
]
} |
in the presence of distant ischemia , peri-infarctional ischemia was in 11 patients ( 85 % ) of the patients with peri-infarctional ischemia only , incomplete obstruction of the infarct vessel was observed . | NA | {
"id": "C0022116",
"name": "ischemia",
"pos": [
27,
35
]
} | {
"id": "C0021308",
"name": "infarct",
"pos": [
178,
185
]
} |
it is concluded that , by the distinction between peri-infarctional and distant ischemia , the presence of significant stenosis in non-infarct vessels can be non-invasively predicted from tomographic thallium scintigraphy with dipyridamole . | NA | {
"id": "C0022116",
"name": "ischemia",
"pos": [
80,
88
]
} | {
"id": "C0021308",
"name": "infarct",
"pos": [
135,
142
]
} |
in addition , varying numbers of spindle-shaped or elongated positively staining cells , which were probably schwann cells and their precursor cells , were demonstrated in ganglioneuroblastoma and differentiating neuroblastoma . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
81,
86
]
} | {
"id": "C0018956",
"name": "precursor cells",
"pos": [
133,
148
]
} |
clinical data suggest that the osteoporosis of von gierke 's disease is due to hypoglycemia or a metabolic sequela thereof , such as insulinopenia , but pathologic study of patients treated by newer techniques of maintaining euglycemia in gsd is needed . | NA | {
"id": "C0017920",
"name": "von gierke 's disease",
"pos": [
47,
68
]
} | {
"id": "C0017919",
"name": "gsd",
"pos": [
239,
242
]
} |
tuberous sclerosis is characterized by the development of hamartomas in many organs , particularly the brain , skin , heart , and kidney . | NA | {
"id": "C0041341",
"name": "tuberous sclerosis",
"pos": [
0,
18
]
} | {
"id": "C0018552",
"name": "hamartomas",
"pos": [
58,
68
]
} |
of those who survived 3 months , at least 37 % required treatment for persistent rest pain or had skin ulceration or necrosis , or had developed gangrene or come to amputation . | NA | {
"id": "C0027540",
"name": "necrosis",
"pos": [
117,
125
]
} | {
"id": "C0017086",
"name": "gangrene",
"pos": [
145,
153
]
} |
different beta agonists stimulate camp accumulation in intact l8 cells with the following potency : isoproterenol greater than procaterol = epinephrine greater than norepinephrine greater than phenylephrine . | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
140,
151
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
165,
179
]
} |
in comparison with detajmium , prajmalium , ajmaline , quinidine , lidocaine , disopyramide , propranolol , and ethmozin the substance gs 015 is tested on the aconitin-induced arrhythmia of the rat , the auricular fibrillation by aconitin of the dog , the ventricular arrhythmia induced by ouabaine of the dog , the arrhythmia caused by calcium chloride of the rat , and the arrhythmia induced by barium chloride of the rabbit . | NA | {
"id": "C0032899",
"name": "prajmalium",
"pos": [
31,
41
]
} | {
"id": "C0001888",
"name": "ajmaline",
"pos": [
44,
52
]
} |
the specific toxicity to the lung can be explained in part by the accumulation of paraquat into the alveolar type i and type ii epithelial cells by a process that has been shown to accumulate endogenous diamines and polyamines . | NA | {
"id": "C0011957",
"name": "diamines",
"pos": [
203,
211
]
} | {
"id": "C0032433",
"name": "polyamines",
"pos": [
216,
226
]
} |
we have developed a marker system that is based on the identification of cells of mus musculus origin in m. musculus-m. caroli chimeras by in situ dna-dna hybridization using a cloned probe to m. musculus satellite dna . | NA | {
"id": "C0012854",
"name": "dna",
"pos": [
147,
150
]
} | {
"id": "C0012934",
"name": "satellite dna",
"pos": [
205,
218
]
} |
although the association is rare , it is important to consider carcinoid tumour as a cause of idiopathic retroperitoneal fibrosis , even in the absence of the carcinoid syndrome . | NA | {
"id": "C0007095",
"name": "carcinoid tumour",
"pos": [
63,
79
]
} | {
"id": "C0024586",
"name": "carcinoid syndrome",
"pos": [
159,
177
]
} |
[ pseudarthrosis of the femur neck and ununited ipsilateral diaphyseal fracture . value of an adjustable 2-piece nail plate ] . | NA | {
"id": "C0033785",
"name": "pseudarthrosis",
"pos": [
2,
16
]
} | {
"id": "C0016665",
"name": "ununited",
"pos": [
39,
47
]
} |
for decades , hyperlipidemia , and more precisely hypercholesterolemia , has been considered as a major coronary heart disease factor . | NA | {
"id": "C0020473",
"name": "hyperlipidemia",
"pos": [
14,
28
]
} | {
"id": "C0020443",
"name": "hypercholesterolemia",
"pos": [
50,
70
]
} |
to investigate some parameters involved in postmenopausal calcium metabolism we have measured fsh , lh , estradiol ( e2 ) , parathyroid hormone ( pth ) calcitonin ( ct ) , 25-hydroxy-vitamin d3 ( 25-oh-d3 ) , total calcium ( cat ) and ionic calcium ( ca++ ) serum levels in 20 healthy postmenopausal women and 20 premenopausal women . | NA | {
"id": "C0006657",
"name": "25-hydroxy-vitamin d3",
"pos": [
172,
193
]
} | {
"id": "C2713074",
"name": "25-oh-d3",
"pos": [
196,
204
]
} |
concentrations of the plasma catecholamines ( ca ) , adrenaline , noradrenaline and dopamine , were measured using a specific and sensitive radioenzymatic assay in 7 ewes and their single lambs chronically catheterized in utero between days 127 and 145 of gestation and during the first week of postnatal life . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
53,
63
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
66,
79
]
} |
plasma adrenaline , noradrenaline and dopamine concentrations in lambs at birth rose significantly to 1 800 +/- 520 , 3 782 +/- 781 and 575 +/- 90 pg/ml , respectively . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
7,
17
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
20,
33
]
} |
on days 5 and 10 after delivery , plasma dopamine and noradrenaline concentrations were higher in calves delivered by caesarean section than in those born spontaneously at term , while plasma adrenaline concentration was never different between the two groups . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
54,
67
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
192,
202
]
} |
the in vitro degradability of proteins was significantly less in defaunated than in faunated animals : 17 , 19 , 28 and 64 % with lupine grain , peanut cake , soybean cake and fish meal proteins , respectively . | NA | {
"id": "C0033684",
"name": "proteins",
"pos": [
30,
38
]
} | {
"id": "C0598294",
"name": "fish",
"pos": [
176,
180
]
} |
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