text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
the effects of noradrenaline , adrenaline and isoprenaline on neuromuscular transmission in the rat diaphragm and the influence of adrenergic blocking agents on these actions were investigated.2 . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
15,
28
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
31,
41
]
} |
the resting membrane potential of the muscle fibre was increased by adrenaline ( 5 x 10 ( -6 ) -10 ( -5 ) g/ml . ) and isoprenaline ( 5 x 10 ( -6 ) g/ml . ) up to 3-4 mv , but noradrenaline ( 5 x 10 ( -6 ) -10 ( -5 ) g/ml . ) had little effect.3 . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
68,
78
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
176,
189
]
} |
the amplitude and the half-decay time of the end-plate potential ( e.p.p . ) were increased by noradrenaline ( 1 x 10 ( -6 ) g/ml . ) , adrenaline ( 1 x 10 ( -7 ) -10 ( -5 ) g/ml . ) and isoprenaline ( 1-5 x 10 ( -6 ) g/ml . ) . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
95,
108
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
136,
146
]
} |
the potentiation of the amplitude of the e.p.p . was greater with noradrenaline than with adrenaline and isoprenaline.4 . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
66,
79
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
90,
100
]
} |
noradrenaline ( 5 x 10 ( -6 ) g/ml . ) and adrenaline ( 5 x 10 ( -6 ) g/ml . ) augmented the extracellularly recorded end-plate current ( e.p.c . ) , but they had no effect on the half duration , nor on the action current ( a.c. ) of the nerve terminal , nor on the synaptic delay . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
0,
13
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
43,
53
]
} |
the actions of noradrenaline and adrenaline on e.p.c . were abolished by phentolamine ( 2 x 10 ( -6 ) g/ml . ) , but not by pronethalol ( 2 x 10 ( -6 ) g/ml . ) .7 . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
15,
28
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
33,
43
]
} |
it was concluded that noradrenaline acts on the nerve ending increasing the release of transmitter , and that isoprenaline acts on the post-synaptic membrane enhancing the input resistance , while adrenaline has both presynaptic and post-synaptic actions . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
22,
35
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
197,
207
]
} |
the currents in ( b ) and ( c ) are considered to be carried by na ions since they both reversed direction at the same potential which was on the average within 0.3 mv of the equilibrium potential for na ions , 10.4 mv at 0 degrees c and 11 mv at 16.5 degrees c , as estimated from measurements made with a cation-sensitive glass electrode.3 . | NA | {
"id": "C0022023",
"name": "ions",
"pos": [
67,
71
]
} | {
"id": "C0007447",
"name": "cation",
"pos": [
307,
313
]
} |
the fractional permeation of heart cell water by l-arabinose and d-xylose after a standard period of perfusion is less the higher the extracellular pentose concentration.2 . | NA | {
"id": "C0003682",
"name": "l-arabinose",
"pos": [
49,
60
]
} | {
"id": "C0030894",
"name": "pentose",
"pos": [
148,
155
]
} |
the fractional permeation of heart cell water by l-arabinose and d-xylose after a standard period of perfusion is less the higher the extracellular pentose concentration.2 . | NA | {
"id": "C0043375",
"name": "xylose",
"pos": [
67,
73
]
} | {
"id": "C0030894",
"name": "pentose",
"pos": [
148,
155
]
} |
world incidence of hydatid disease in general and pulmonary hydatid disease in particular with special reference to india . | NA | {
"id": "C0013502",
"name": "hydatid disease",
"pos": [
19,
34
]
} | {
"id": "C0013505",
"name": "pulmonary hydatid disease",
"pos": [
50,
75
]
} |
from 13 to 20 % of the newly formed lipid was diglyceride , and over 95 % of it was localized in the central lipid-storage vacuole rather than in organelle systems concerned with esterification , thus indicating intracellular segregation of newly synthesized partial glycerides . | NA | {
"id": "C0023779",
"name": "lipid",
"pos": [
36,
41
]
} | {
"id": "C0017860",
"name": "glycerides",
"pos": [
267,
277
]
} |
hydroxy acids appeared to be present in all the glycolipids , but the concentration was very low in cerebrosides isolated from high density lipoproteins and erythrocytes , and in diglycosyl ceramide and globoside of the low density lipoproteins . | NA | {
"id": "C0007805",
"name": "cerebrosides",
"pos": [
100,
112
]
} | {
"id": "C0007745",
"name": "ceramide",
"pos": [
190,
198
]
} |
hydroxy acids appeared to be present in all the glycolipids , but the concentration was very low in cerebrosides isolated from high density lipoproteins and erythrocytes , and in diglycosyl ceramide and globoside of the low density lipoproteins . | NA | {
"id": "C0007745",
"name": "ceramide",
"pos": [
190,
198
]
} | {
"id": "C0017647",
"name": "globoside",
"pos": [
203,
212
]
} |
these results suggest that much of the me which is taken up , is hydrolyzed to ffa , and that the fatty acids derived from me are available for further metabolism . | NA | {
"id": "C0015688",
"name": "ffa",
"pos": [
79,
82
]
} | {
"id": "C0015684",
"name": "fatty acids",
"pos": [
98,
109
]
} |
excretion rates of noradrenaline , adrenaline , sodium , potassium and creatinine did not differ significantly between mawson and melbourne , nor did urine flow rates.4 . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
19,
32
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
35,
45
]
} |
[ applicability of gamranityt ion exchangers and sd cations exchanger in the preparation of aqua pro injections ] . | NA | {
"id": "C0022023",
"name": "ion",
"pos": [
30,
33
]
} | {
"id": "C0007447",
"name": "cations",
"pos": [
52,
59
]
} |
[ effect of dopa and alpha-methyl-dopa on the development of neurogenic dystrophy of the gastric wall and catecholamine content of the stomach ] . | NA | {
"id": "C0013023",
"name": "dopa",
"pos": [
12,
16
]
} | {
"id": "C0025741",
"name": "alpha-methyl-dopa",
"pos": [
21,
38
]
} |
[ effect of dopa and alpha-methyl-dopa on the development of neurogenic dystrophy of the gastric wall and catecholamine content of the stomach ] . | NA | {
"id": "C0013023",
"name": "dopa",
"pos": [
12,
16
]
} | {
"id": "C0007412",
"name": "catecholamine",
"pos": [
106,
119
]
} |
the escherichia coli 30s ribosomal protein p10 , the product of the str gene , known to be involved only in the initiation of protein syntehsis , is required for all bacteriophage t4 protein synthesis . | NA | {
"id": "C0035552",
"name": "ribosomal protein",
"pos": [
25,
42
]
} | {
"id": "C0033684",
"name": "protein",
"pos": [
183,
190
]
} |
[ a case of degenerated villous tumor of the rectum with water-electrolyte loss and ion unbalance ] . | NA | {
"id": "C0013832",
"name": "electrolyte",
"pos": [
63,
74
]
} | {
"id": "C0022023",
"name": "ion",
"pos": [
84,
87
]
} |
the possibility is considered that after exposure to antigenic stimulation , an immunologically reactive cell population is formed which is radioresistant but sensitive to als , unlike the precursor cells from which this population is derived , which are radiosensitive and sensitive to als . | NA | {
"id": "C0007634",
"name": "cell",
"pos": [
105,
109
]
} | {
"id": "C0018956",
"name": "precursor cells",
"pos": [
189,
204
]
} |
the histone , neutral and acidic nuclear-protein content of br6 mouse mammary tumours have been measured and related to growth rate and hormone responsiveness . | NA | {
"id": "C0019652",
"name": "histone",
"pos": [
4,
11
]
} | {
"id": "C0028589",
"name": "nuclear-protein",
"pos": [
33,
48
]
} |
in unresponsive tumours , histone and neutral nuclear-protein content was inversely correlated with growth rate while acidic nuclear-proteins were directly correlated with growth rate . | NA | {
"id": "C0019652",
"name": "histone",
"pos": [
26,
33
]
} | {
"id": "C0028589",
"name": "nuclear-proteins",
"pos": [
125,
141
]
} |
the histone content of these tumours was low when compared to pregnancy dependent tumours growing at the same rate under the same physiological conditions.in vitro incorporation of labelled amino acids into total protein and the nuclear proteins was also measured . | NA | {
"id": "C0019652",
"name": "histone",
"pos": [
4,
11
]
} | {
"id": "C0028589",
"name": "nuclear proteins",
"pos": [
229,
245
]
} |
when they were exposed to distilled water at 29 degrees c , the rate of water uptake was 8.4 +/- 0.4 mul./cm ( 2 ) .hr ; | NA | {
"id": "C0790233",
"name": "distilled water",
"pos": [
26,
41
]
} | {
"id": "C0043047",
"name": "water",
"pos": [
72,
77
]
} |
[ metabolism and toxicity of therapeutic chelating agents . 8. excretion of sodium , potassium , magnesium and zinc ] . | NA | {
"id": "C0025519",
"name": "metabolism",
"pos": [
2,
12
]
} | {
"id": "C0221102",
"name": "excretion",
"pos": [
63,
72
]
} |
a simple and rapid screening test which differentiates sickle-cell trait and sickle-cell anaemia is described . | NA | {
"id": "C0037054",
"name": "sickle-cell trait",
"pos": [
55,
72
]
} | {
"id": "C0002895",
"name": "sickle-cell anaemia",
"pos": [
77,
96
]
} |
results intermediate between the sickle-cell trait and sickle-cell anaemia are obtained in unusual cases of sickle-cell anaemia with high foetal haemoglobin . | NA | {
"id": "C0037054",
"name": "sickle-cell trait",
"pos": [
33,
50
]
} | {
"id": "C0002895",
"name": "sickle-cell anaemia",
"pos": [
108,
127
]
} |
standard curves were obtained for the three following representative samples : ( a ) a mixture of beef brain gangliosides , ( b ) tay-sachs ganglioside , and ( c ) hematoside-nana . | NA | {
"id": "C0017082",
"name": "gangliosides",
"pos": [
109,
121
]
} | {
"id": "C0016897",
"name": "hematoside",
"pos": [
164,
174
]
} |
phosphorylcholine-1,2- ( 14 ) c and choline-1,2- ( 14 ) c-labeled cytidine diphosphate choline are incorporated into lecithin by whole homogenates and particulate fractions of rat retina with optimal incorporation of label by the microsomal fraction . | NA | {
"id": "C0031716",
"name": "phosphorylcholine",
"pos": [
0,
17
]
} | {
"id": "C0008405",
"name": "choline",
"pos": [
87,
94
]
} |
phosphorylcholine-1,2- ( 14 ) c and choline-1,2- ( 14 ) c-labeled cytidine diphosphate choline are incorporated into lecithin by whole homogenates and particulate fractions of rat retina with optimal incorporation of label by the microsomal fraction . | NA | {
"id": "C0008405",
"name": "choline",
"pos": [
10,
17
]
} | {
"id": "C0010725",
"name": "cytidine diphosphate",
"pos": [
66,
86
]
} |
the lipogenic activity of albumin was confirmed by the high potency of the albumin isolated in a nearly pure form from proteins of d > 1.21 by precipitation with trichloroacetic acid and extraction with ethanol . | NA | {
"id": "C0001924",
"name": "albumin",
"pos": [
26,
33
]
} | {
"id": "C0033684",
"name": "proteins",
"pos": [
119,
127
]
} |
chemical and isotopic analysis of the recovered horse serum albumin revealed that its free fatty acid content was the same as that of rabbit serum albumin . | NA | {
"id": "C0001924",
"name": "albumin",
"pos": [
60,
67
]
} | {
"id": "C0036773",
"name": "serum albumin",
"pos": [
141,
154
]
} |
[ amino acid metabolism disorders in infancy with special reference to phenylketonuria . 3. general problems of diseases of aminoacid transport and metabolism . personal results ] . | NA | {
"id": "C0002514",
"name": "amino acid metabolism disorders",
"pos": [
2,
33
]
} | {
"id": "C0031485",
"name": "phenylketonuria",
"pos": [
71,
86
]
} |
the marrow cells , demonstrated to contain precursors of the antibody-forming cells produced during this synergistic immune response , also show a form of antigen-specificity . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
11,
16
]
} | {
"id": "C0018956",
"name": "precursors",
"pos": [
43,
53
]
} |
in order to determine whether the genetic control of immune response can be correlated with the number of antigen-sensitive precursor cells , spleen cell suspensions from normal and immunized sjl and dba/1 donor mice were transplanted into lethally x-irradiated syngeneic recipients ( incapable of immune response ) along with ( t , g ) -pro -- l . | NA | {
"id": "C0018956",
"name": "precursor cells",
"pos": [
124,
139
]
} | {
"id": "C0007634",
"name": "cell",
"pos": [
149,
153
]
} |
on the other hand , it gives a `` '' false negative '' '' reaction in the sanfilippo syndrome ( perhaps because the characteristically elevated glycosaminoglycan in this disease , heparan sulfate , is not synthesized by cultured skin fibroblasts ) , and in the marfan syndrome . | NA | {
"id": "C0017973",
"name": "d glycosaminoglyc",
"pos": [
142,
159
]
} | {
"id": "C0019143",
"name": ", hepar",
"pos": [
178,
185
]
} |
[ effect of cyclopropane and fluothane anesthesia on metabolism and excretion of glucocorticoids in the aged ] . | NA | {
"id": "C0025519",
"name": "metabolism",
"pos": [
53,
63
]
} | {
"id": "C0221102",
"name": "excretion",
"pos": [
68,
77
]
} |
[ comparative study of antigenic structure by immunoelectrophoretic analysis and by characterization reactions of enzymatic activities of the antigenic extracts of pathogenic fungi of the genus aspergillus ( a. fumigatus , a. flavus , a. terreus and a. nidulans ) ] . | NA | {
"id": "C0003320",
"name": "antigenic",
"pos": [
23,
32
]
} | {
"id": "C0003330",
"name": "antigenic",
"pos": [
142,
151
]
} |
[ comparative study of antigenic structure by immunoelectrophoretic analysis and by characterization reactions of enzymatic activities of the antigenic extracts of pathogenic fungi of the genus aspergillus ( a. fumigatus , a. flavus , a. terreus and a. nidulans ) ] . | NA | {
"id": "C0004034",
"name": "aspergillus",
"pos": [
194,
205
]
} | {
"id": "C0004037",
"name": "fumigatus",
"pos": [
211,
220
]
} |
[ labelled endogenous catecholamines in the central nervous system . radioautographic study after tritiated l-3,4 dihydroxyphenylalanine ( dopa-3h ) ] . | NA | {
"id": "C0007412",
"name": "catecholamines",
"pos": [
22,
36
]
} | {
"id": "C0013023",
"name": "dopa",
"pos": [
139,
143
]
} |
[ anti-adrenal antibodies and addison 's disease . application of the immunofluorescence technic in 100 cases of adrenal insufficiency ] . | NA | {
"id": "C0001403",
"name": "addison 's disease",
"pos": [
30,
48
]
} | {
"id": "C0001623",
"name": "adrenal insufficiency",
"pos": [
113,
134
]
} |
[ electron microscopic study of the mouse fetal myocardium : influence of adrenaline and noradrenaline on its content of specific granules ] . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
74,
84
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
89,
102
]
} |
criss-cross studies using antisera specific for gamma 1 or gamma 2a heavy chains showed that the membrane receptor has the same heavy chain as will be present in the eventual product of that cell , the humoral antibody . | NA | {
"id": "C0020960",
"name": "antisera",
"pos": [
26,
34
]
} | {
"id": "C0003241",
"name": "antibody",
"pos": [
210,
218
]
} |
an abnormal lipoprotein , containing a high proportion of unesterified cholesterol and phospholipid , has previously been described as occurring in the serum of patients with obstructive jaundice , and has been called lipoprotein x . | NA | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
12,
23
]
} | {
"id": "C0023819",
"name": "lipoprotein x",
"pos": [
218,
231
]
} |
[ the effect of biogenic amines on respiration and pulmonary circulation . i. acetylcholine inhalation and infusion in the right atrium and the truncus bicaroticus ] . | NA | {
"id": "C0005496",
"name": "biogenic amines",
"pos": [
16,
31
]
} | {
"id": "C0001041",
"name": "acetylcholine",
"pos": [
78,
91
]
} |
[ passive quantitative immunohemolysis of erythrocytes sensitized to an antigen by chromium chloride : practical applications ( hormonal titrations , titrations of bacterial antigens and antibodies , research on immunocompetent cells ) ] . | NA | {
"id": "C0003320",
"name": "antigen",
"pos": [
72,
79
]
} | {
"id": "C0003321",
"name": "bacterial antigens",
"pos": [
164,
182
]
} |
mineral analyses of garden soils , vegetables , and water samples from 21 villages in the sepik and fly river regions of the territory of papua and new guinea , in which the mean prevalence of dental caries ranged from 0 to 29.5 % decayed teeth per person , have shown the following relationships between variations in the caries prevalence and the amounts of certain elements : ( 1 ) a strong inverse association with concentrations of alkali and alkaline earth elements , especially strontium , barium , potassium , magnesium , calcium , and lithium , in garden soils . ( 2 ) a possible direct association with concentrations of lead and copper in village garden soils . ( 3 ) consistent evidence of inverse associations with concentrations of vanadium , molybdenum , manganese , aluminium , titanium , and phosphorus and of direct associations with concentrations of lead , copper , chromium , zinc , and selenium in the staple foodstuffs-namely , sago , sweet potato , and chinese taro.in general , analyses of soils and vegetables from 22 villages in the highlands of papua-new guinea have confirmed the soil associations with the caries prevalence reported for villages in the sepik and fly river regions . | NA | {
"id": "C0013879",
"name": "elements",
"pos": [
368,
376
]
} | {
"id": "C0031705",
"name": "phosphorus",
"pos": [
809,
819
]
} |
studies on serum enzymes in cardiovascular diseases with special reference to serum lactic dehydrogenase isoenzymes . | NA | {
"id": "C0014442",
"name": "enzymes",
"pos": [
17,
24
]
} | {
"id": "C0022173",
"name": "isoenzymes",
"pos": [
105,
115
]
} |
[ study of hepatic alcohol dehydrogenase inhibition by pyrazole . i. in vivo action on ethanol and 2-phenylethanol metabolism ] . | NA | {
"id": "C0001962",
"name": "ethanol",
"pos": [
87,
94
]
} | {
"id": "C0031398",
"name": "2-phenylethanol",
"pos": [
99,
114
]
} |
[ ankylosing hyperostosis of the spine ( forestier 's disease ) in diabetics . systematic x-ray examinations of 1,000 diabetics ] . | NA | {
"id": "C0020492",
"name": "hyperostosis",
"pos": [
13,
25
]
} | {
"id": "C0020498",
"name": "forestier 's disease",
"pos": [
41,
61
]
} |
cognitive development of young children in residential care : a study of children aged 24 months . | NA | {
"id": "C0728836",
"name": "of young children",
"pos": [
22,
39
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
73,
81
]
} |
[ glucose loading and arginine infusions in newborn infants . effect on growth hormone , blood sugar , fatty acids and glycerin ] . | NA | {
"id": "C0017725",
"name": "glucose",
"pos": [
2,
9
]
} | {
"id": "C0005802",
"name": "blood sugar",
"pos": [
89,
100
]
} |
[ effect of histamine , carbachol , pentagastrin and chick gastrin extracts on gastric acid secretion in unanesthetized chickens ] . | NA | {
"id": "C0030859",
"name": "pentagastrin",
"pos": [
36,
48
]
} | {
"id": "C0017151",
"name": "gastrin",
"pos": [
59,
66
]
} |
effect of ethyl alcohol on urinary excretion of noradrenaline and adrenaline in patients with threatened premature delivery . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
48,
61
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
66,
76
]
} |
[ typhoid endemy in finistere . survey of commune equipment ( drinking water , used water , domestic rubbish ) and the risk of water pollution ] . | NA | {
"id": "C0599638",
"name": "drinking water",
"pos": [
62,
76
]
} | {
"id": "C0043047",
"name": "water",
"pos": [
127,
132
]
} |
[ spirometry as a method for the evaluation of the functional condition of the lungs in respiratory tract diseases ] . | NA | {
"id": "C0024115",
"name": "the",
"pos": [
29,
32
]
} | {
"id": "C0035242",
"name": "respiratory tract diseases",
"pos": [
88,
114
]
} |
[ a recent epidemic due to arbovirus infections of the dengue type in tahiti . comparative study of the 1964 epidemic ] . | NA | {
"id": "C0003723",
"name": "arbovirus infections",
"pos": [
27,
47
]
} | {
"id": "C0011311",
"name": "dengue",
"pos": [
55,
61
]
} |
a temporal study of enzymes , isozymes , and histochemical changes in duchenne 's dystrophy and neurogenic atrophy . | NA | {
"id": "C0014442",
"name": "enzymes",
"pos": [
20,
27
]
} | {
"id": "C0022173",
"name": "isozymes",
"pos": [
30,
38
]
} |
[ incubation of sheep adrenals with 1,2 3 h-corticosterone in vitro . role of cofactors in the synthesis of 18-hydroxycorticosterone and aldosterone in vitro . conversion products ] . | NA | {
"id": "C0010124",
"name": "corticosterone",
"pos": [
44,
58
]
} | {
"id": "C0000172",
"name": "18-hydroxycorticosterone",
"pos": [
108,
132
]
} |
elements that show lsm include lysosomes , pinosomes , ingested carbon particles , lipoidal granules , and unidentified particles that appear as bright objects in positive phase contrast . | NA | {
"id": "C0013879",
"name": "elements",
"pos": [
0,
8
]
} | {
"id": "C0007009",
"name": "carbon",
"pos": [
64,
70
]
} |
[ speed of propagation of the rheographic wave in the lower extremities in normal subjects , patients with arteriosclerosis obliterans and subjects with peripheral arterial sclerosis ] . | NA | {
"id": "C0003851",
"name": "arteriosclerosis obliterans",
"pos": [
107,
134
]
} | {
"id": "C0003850",
"name": "arterial sclerosis",
"pos": [
164,
182
]
} |
role of the entero-hepatic cycle of indomethacin on its metabolism , distribution in tissues and its excretion by rats , dogs and monkeys . | NA | {
"id": "C0025519",
"name": "metabolism",
"pos": [
56,
66
]
} | {
"id": "C0221102",
"name": "excretion",
"pos": [
101,
110
]
} |
comparative effects of salicylic acid , phenylbutazone , probenecid and other anions on the metabolism , distribution and excretion of indomethacin by rats . | NA | {
"id": "C0025519",
"name": "metabolism",
"pos": [
92,
102
]
} | {
"id": "C0221102",
"name": "excretion",
"pos": [
122,
131
]
} |
reactions of the cytostatic and antitumour agent , cis-platinum ( ii ) diamminedichloride , and its trans isomer with purine , adenine and its n-9 derivatives were followed spectrophotometrically in dilute aqueous solutions . | NA | {
"id": "C0034140",
"name": "purine",
"pos": [
118,
124
]
} | {
"id": "C0001407",
"name": "adenine",
"pos": [
127,
134
]
} |
the values of dissociation constants , reaction rate constants and activation energies of the reactions of the cis and trans isomers with purine , adenine , and its derivatives were in most cases comparable . | NA | {
"id": "C0034140",
"name": "purine",
"pos": [
138,
144
]
} | {
"id": "C0001407",
"name": "adenine",
"pos": [
147,
154
]
} |
twenty-four hours post-glycerol injection , when acute renal failure was evident as indicated by blood urea nitrogen ( bun ) values of 116.9 and 63.8 mg/100 ml in water- and saline-drinking rats , respectively , co and rbf returned to normal , except that the co of of water-drinking rats was slightly higher than control . | NA | {
"id": "C0043047",
"name": "water",
"pos": [
163,
168
]
} | {
"id": "C0599638",
"name": "water-drinking",
"pos": [
269,
283
]
} |
both adenosine and adenosine triphosphate ( 10 ( -5 ) m ) reduced the efflux of 3h-norepinephrine during nerve stimulation with electrical impulses . | NA | {
"id": "C0001443",
"name": "adenosine",
"pos": [
5,
14
]
} | {
"id": "C0001480",
"name": "adenosine triphosphate",
"pos": [
19,
41
]
} |
hemorrhagic shock was induced by bleeding to a mean arterial blood pressure ( mabp ) of 40 mm hg for 150 minutes followed by reinfusion of all remaining shed blood . | NA | {
"id": "C0036982",
"name": "hemorrhagic shock",
"pos": [
0,
17
]
} | {
"id": "C0019080",
"name": "bleeding",
"pos": [
33,
41
]
} |
the calculated amount of enzyme released into the baboons ' circulation ( cpk-mbr ) correlated well ( r = 0.991 ) with the amount of mb isoenzyme depleted from the myocardium ( cpk-mbd ) when a previously determined decay constant ( kd ) was used , but not when kd was calculated from individual curves or when cpk-mm values were used . | NA | {
"id": "C0014442",
"name": "enzyme",
"pos": [
25,
31
]
} | {
"id": "C0022173",
"name": "isoenzyme",
"pos": [
136,
145
]
} |
a rotating porous cell was specially designed to hold the immobilized enzymes firmly and to allow the reaction mixture to pass through the enzyme layer easily , thus catalyzing the enzymatic transformation quickly . | NA | {
"id": "C0014444",
"name": "immobilized enzymes",
"pos": [
58,
77
]
} | {
"id": "C0014442",
"name": "enzyme",
"pos": [
139,
145
]
} |
a study of the lysosomal hydrolases bete-galactosidase , beta-glucuronidase , n-acetyl-beta-d-glucosaminidase , and arylsulphatases a and b has been carried out on fibroblasts cultured from seven patients with cystinosis and eight control subjects . beta-galactosidase activity was found to be consistently lower in cells derived from cystinotics , while the other enzymes studied showed no significant differences between normals and cystinotics . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
164,
175
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
316,
321
]
} |
post-burn granulation tissues showed an extraordinary high prolyl hydroxylase ( ec 1.14.11.2 ; proline , 2-oxoglutarate dioxygenase ) activity , 25 to 50 times higher than the mean value of human normal skins from the frontal thighs of 15 subjects , 385 +/- 247 ( s.d . ) | NA | {
"id": "C3665675",
"name": "prolyl hydroxylase",
"pos": [
59,
77
]
} | {
"id": "C0599874",
"name": "dioxygenase",
"pos": [
120,
131
]
} |
for example in serum of patients with juvenile diabetes mellitus there is a characteristic elevation of hexosaminidase b and less consistently , of hexosaminidase a . | NA | {
"id": "C0005270",
"name": "hexosaminidase",
"pos": [
104,
118
]
} | {
"id": "C0162330",
"name": "hexosaminidase a",
"pos": [
148,
164
]
} |
similarly , the distribution of the hexosaminidase isozymes in serum is altered during pregnancy , where there is usually a significant rise in hexosaminidase a and i ( p ) . | NA | {
"id": "C0005270",
"name": "hexosaminidase",
"pos": [
36,
50
]
} | {
"id": "C0162330",
"name": "a",
"pos": [
161,
162
]
} |
dopa is isolated from interfering substances , especially catecholamines , by adsorption onto aluminium oxide , elution with 0.1 m hcl , then passed through a cation-exchange column . | NA | {
"id": "C0013023",
"name": "dopa",
"pos": [
0,
4
]
} | {
"id": "C0007412",
"name": "catecholamines",
"pos": [
58,
72
]
} |
cortisol , androstenedione , testosterone , dehydroepiandrosterone sulphate ( dhas ) and free dehydroepiandrosterone ( dha ) were measured in plasma of ten women affected by amenorrhoea with hyperprolactinaemia and eleven women affected by secondary hypothalamic amenorrhoea ; | NA | {
"id": "C0057277",
"name": "dehydroepiandrosterone sulphate",
"pos": [
44,
75
]
} | {
"id": "C0011185",
"name": "free",
"pos": [
89,
93
]
} |
all subjects were hospitalized and 17-ketosteroids , 17oh-corticosteroids and total dehydroepiandrosterone were also measured in urine . | NA | {
"id": "C0000167",
"name": "17-ketosteroids",
"pos": [
35,
50
]
} | {
"id": "C0001617",
"name": "corticosteroids",
"pos": [
58,
73
]
} |
plasma cortisol , androstenedione and testosterone and urinary 17-oxosteroids and 17oh-corticosteroids were not significantly differnt in the three groups . | NA | {
"id": "C0002860",
"name": "androstenedione",
"pos": [
18,
33
]
} | {
"id": "C0000167",
"name": "17-oxosteroids",
"pos": [
63,
77
]
} |
plasma cortisol , androstenedione and testosterone and urinary 17-oxosteroids and 17oh-corticosteroids were not significantly differnt in the three groups . | NA | {
"id": "C0000167",
"name": "17-oxosteroids",
"pos": [
63,
77
]
} | {
"id": "C0001617",
"name": "corticosteroids",
"pos": [
87,
102
]
} |
intravenous iron was given over 2 weeks as an iron dextran ( equivalent to 100 mg elemental iron ) . | NA | {
"id": "C0302583",
"name": "iron",
"pos": [
12,
16
]
} | {
"id": "C0022092",
"name": "iron",
"pos": [
92,
96
]
} |
oral iron was given daily as ferrous sulphate ( equivalent to 100 mg elemental iron ) in a wax matrix tablet . | NA | {
"id": "C0302583",
"name": "iron",
"pos": [
5,
9
]
} | {
"id": "C0060282",
"name": "ferrous sulphate",
"pos": [
29,
45
]
} |
we examined naloxone-precipitated withdrawal as a means for rapid opiate detoxification and induction onto naltrexone . | NA | {
"id": "C0027358",
"name": "naloxone",
"pos": [
12,
20
]
} | {
"id": "C0027360",
"name": "naltrexone",
"pos": [
107,
117
]
} |
it appears that naproxen and naproxen sodium are analgesics with efficacy equal to aspirin and may prove to be rational substitutes for currently available analgesics in some painful states in which longer pain relief would be desireable . | NA | {
"id": "C0027396",
"name": "naproxen",
"pos": [
16,
24
]
} | {
"id": "C0546873",
"name": "naproxen sodium",
"pos": [
29,
44
]
} |
in the initial study , 11 patients with liver disease ( cirrhosis and fibrosis ) had a longer half-life ( t 1/2 ( beta ) of 99.2 +/- 23.2 hr after a single intravenous bolus of 0.1 mg/kg of d than to age-matched normal subjects ( 46.6 +/- 14.2 ) . | NA | {
"id": "C0023895",
"name": "liver",
"pos": [
40,
45
]
} | {
"id": "C0023890",
"name": "cirrhosis",
"pos": [
56,
65
]
} |
the changes in plasma concentrations of free amino acids , glucose and glucagon , and tissue concentrations of free amino acids , were similar after the intravenous administration of glycyl-leucine and an equimolar mixture of free glycine and leucine . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
45,
56
]
} | {
"id": "C0017890",
"name": "glycine",
"pos": [
231,
238
]
} |
sham-operated and bilaterally nephrectomized rats were injected intravenously with glycyl-l-leucine , glycylglycine and glycylsarcosine , and the concentrations of these dipeptides in plasma and muscle , liver , renal cortex ( in the sham-operated rats ) and intestinal mucosa at various intervals were determined . | NA | {
"id": "C0017984",
"name": "glycylglycine",
"pos": [
102,
115
]
} | {
"id": "C0012512",
"name": "dipeptides",
"pos": [
170,
180
]
} |
glycyl-leucine and glycylglycine were not detected in tissues of control rats injected with these dipeptides , but glycylsarcosine was recovered from all four tissues examined . | NA | {
"id": "C0017984",
"name": "glycylglycine",
"pos": [
19,
32
]
} | {
"id": "C0012512",
"name": "dipeptides",
"pos": [
98,
108
]
} |
enterectomy did not have a remarkable effect on plasma half-life of glycylglycine but it allowed recovery of this dipeptide from renal cortex , liver and muscle . | NA | {
"id": "C0017984",
"name": "glycylglycine",
"pos": [
68,
81
]
} | {
"id": "C0012512",
"name": "dipeptide",
"pos": [
114,
123
]
} |
prostaglandin a- , prostaglandin e- and prostaglandin f-like substances were determined radioimmunologically in antral biopsy material obtained by endoscopy . | NA | {
"id": "C0033554",
"name": "prostaglandin",
"pos": [
0,
13
]
} | {
"id": "C0033559",
"name": "prostaglandin e",
"pos": [
19,
34
]
} |
prostaglandin a- , prostaglandin e- and prostaglandin f-like substances were determined radioimmunologically in antral biopsy material obtained by endoscopy . | NA | {
"id": "C0033554",
"name": "prostaglandin",
"pos": [
0,
13
]
} | {
"id": "C0033561",
"name": "prostaglandin f",
"pos": [
40,
55
]
} |
the 24 h urinary excretion of adrenaline , noradrenaline , normetadrenaline , metadrenaline and vanilloylmandelic acid has been compared in 17 male normotensive subjects and 25 age-matched male hypertensive patients studied under similar in-patient conditions . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
30,
40
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
43,
56
]
} |
the 24 h urinary excretion of adrenaline , noradrenaline , normetadrenaline , metadrenaline and vanilloylmandelic acid has been compared in 17 male normotensive subjects and 25 age-matched male hypertensive patients studied under similar in-patient conditions . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
30,
40
]
} | {
"id": "C0025562",
"name": "metadrenaline",
"pos": [
78,
91
]
} |
the 24 h urinary excretion of adrenaline , noradrenaline , normetadrenaline , metadrenaline and vanilloylmandelic acid has been compared in 17 male normotensive subjects and 25 age-matched male hypertensive patients studied under similar in-patient conditions . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
43,
56
]
} | {
"id": "C0028385",
"name": "normetadrenaline",
"pos": [
59,
75
]
} |
daily fluctuations in the plasma cortisol level of children with rheumatoid arthritis before and after treatment with tetracosactrin ( 'cortrosyn depot ' ) and corticosteroid hormones . | NA | {
"id": "C0001617",
"name": "corticosteroid",
"pos": [
160,
174
]
} | {
"id": "C0019932",
"name": "hormones",
"pos": [
175,
183
]
} |
one group was untreated with hormones , the second treated with a depot preparation of tetracosactrin , and the third group with corticosteroid hormones . | NA | {
"id": "C0001617",
"name": "corticosteroid",
"pos": [
129,
143
]
} | {
"id": "C0019932",
"name": "hormones",
"pos": [
144,
152
]
} |
a study was carried out in 20 ambulatory patients with various heart diseases and different forms of cardiac arrhythmias to evaluate the anti-arrhythmic effect of acebutolol when given orally ( 400 mg/day ) . | NA | {
"id": "C0018799",
"name": "heart diseases",
"pos": [
63,
77
]
} | {
"id": "C0003811",
"name": "cardiac arrhythmias",
"pos": [
101,
120
]
} |
the locked-in state may be mistaken for coma particularly if there had been a preceding episode of unconsciousness . | NA | {
"id": "C0009421",
"name": "coma",
"pos": [
40,
44
]
} | {
"id": "C0041657",
"name": "unconsciousness",
"pos": [
99,
114
]
} |
in five patients with normal left-ventricular angiograms at rest hypokinesia and dyskinesia occurred during isometric exercise . | NA | {
"id": "C0086439",
"name": "hypokinesia",
"pos": [
65,
76
]
} | {
"id": "C0013384",
"name": "dyskinesia",
"pos": [
81,
91
]
} |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.