text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
functional problems and deformities of the eyes have become a major concern in the surgical treatment of ortital hypertelorism and craniofacial dysostosis , as experience with skeletal relocation for these disorders has been gained . | NA | {
"id": "C0020534",
"name": "hypertelorism",
"pos": [
113,
126
]
} | {
"id": "C0010273",
"name": "craniofacial dysostosis",
"pos": [
131,
154
]
} |
we recommend the use of one dose of physostigmine salicylate , a few minutes before the termination of a general anesthetic , to prevent confusion , struggling , disorientation , or delirium during the recovery from anesthesia . | NA | {
"id": "C0009676",
"name": "disorientation",
"pos": [
162,
176
]
} | {
"id": "C0011206",
"name": "delirium",
"pos": [
182,
190
]
} |
the effects of biofeedback training and voluntary control procedures on heart rate and subjective reactions to 30-sec immersion of the hand in ice water were investigated in five experimental conditions , nine subjects in each condition . | NA | {
"id": "C0020746",
"name": "ice",
"pos": [
143,
146
]
} | {
"id": "C0043047",
"name": "water",
"pos": [
147,
152
]
} |
the authors have also seen a solitary filiform polyp in a patient with previously undiagnosed inflammatory bowel disease , and filiform polyps in the stomach in a patient with documented crohn disease involving the small bowel . | NA | {
"id": "C0021390",
"name": "inflammatory bowel disease",
"pos": [
94,
120
]
} | {
"id": "C0010346",
"name": "crohn disease",
"pos": [
187,
200
]
} |
reoxygenation of experimental tumors following single , massive doses of radiation may be different from that occurring in human tumors during the course of multifraction radiotherapy . | NA | {
"id": "C0027659",
"name": "experimental tumors",
"pos": [
17,
36
]
} | {
"id": "C0027651",
"name": "tumors",
"pos": [
129,
135
]
} |
the preceding results , correlated with the chromatographic homogeneity of guanine aminohydrolase , purified in sephadex g-100 , suggests that the four molecular forms of the native enzyme may be considered as isozymes . | NA | {
"id": "C0014442",
"name": "enzyme",
"pos": [
182,
188
]
} | {
"id": "C0022173",
"name": "isozymes",
"pos": [
210,
218
]
} |
starting from general assumptions on the clinical aspects of homeostasis and on the functional correlations lung-heart in physiological and pathological states , the difficulty to diagnose an individual pulmonary heart disease is stressed , as well as the necessity to differentiate it from the cases of coronary heart disease , when respiratory failure aggravates the latent cardiac ischemia and induces a global cardiac failure . | NA | {
"id": "C0034072",
"name": "pulmonary heart disease",
"pos": [
203,
226
]
} | {
"id": "C0018799",
"name": "the",
"pos": [
365,
368
]
} |
the antiserum was used for immunochemical quantitation of the inhibitor by means of mancini 's single radial immunodiffusion method alone or in combination with a more sensitive double antibody technique followed by autoradiography . | NA | {
"id": "C0020960",
"name": "antiserum",
"pos": [
4,
13
]
} | {
"id": "C0003241",
"name": "antibody",
"pos": [
185,
193
]
} |
recovery of added porphyrin varied between 65 and 90 % for uro- and 70 and 95 % for coproporphyrin . | NA | {
"id": "C0032712",
"name": "porphyrin",
"pos": [
18,
27
]
} | {
"id": "C0009988",
"name": "coproporphyrin",
"pos": [
84,
98
]
} |
the analogy of the anti-hsa autoantibodies and the rheumatoid factors and the theoretical interest of both of them is stressed . | NA | {
"id": "C0004358",
"name": "autoantibodies",
"pos": [
28,
42
]
} | {
"id": "C0035448",
"name": "rheumatoid factors",
"pos": [
51,
69
]
} |
six patients , five of whom had normal and one impaired renal function , and all suffering from purulent arthritis caused by cephalosporin-sensitive germs , were given a seven-day course of 8 g cephacetrile daily . | NA | {
"id": "C3536856",
"name": "cephalosporin",
"pos": [
125,
138
]
} | {
"id": "C0007714",
"name": "cephacetrile",
"pos": [
194,
206
]
} |
it was seen in nuclei of vero and aedes albopictus cells , but not in bhk cells , kb cells , chick embryo fibroblasts , or hela cells . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
51,
56
]
} | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
106,
117
]
} |
when the heightened cyclic amp before s phase was maintained by either inhibiting phosphodiesterase or by adding the 8-bromo derivative of cyclic amp , dna synthesis was also blocked . | NA | {
"id": "C0001455",
"name": "cyclic amp",
"pos": [
20,
30
]
} | {
"id": "C0000661",
"name": "8-bromo",
"pos": [
117,
124
]
} |
cultured skin fibroblasts from patients with cystic fibrosis ( cf ) are more resistant to dexamethasone toxicity than are normal cells . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
14,
25
]
} | {
"id": "C0007634",
"name": "normal cells",
"pos": [
122,
134
]
} |
we now report that , when fibroblasts cultured from obligate cf heterozygotes are exposed to dexamethasone , they have an intermediate survival compared to normal and homozygous cf cells . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
26,
37
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
181,
186
]
} |
when dexamethasone survival was tested on cells from four patients undergoing amniocentesis , cells from a woman at risk of producing a child with cf showed significant dexamethasone resistance , similar to that of fibroblasts derived from lnown cf homozygotes ; | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
42,
47
]
} | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
215,
226
]
} |
by means of a double-label antibody technique , in which we used fluorescein-labeled antibody to reovirus and rhodamine-labeled antibody to insulin , reovirus antigens were found in beta cells . | NA | {
"id": "C0003241",
"name": "antibody",
"pos": [
27,
35
]
} | {
"id": "C0021644",
"name": "antibody",
"pos": [
128,
136
]
} |
ankylosing hyperostosis of the spine ( forestier 's disease ) is a distinct clinical entity which must be differentiated from ankylosing spondylitis ( marie-strumpell 's disease ) and hypertrophic spondylosis . | NA | {
"id": "C0020492",
"name": "hyperostosis",
"pos": [
11,
23
]
} | {
"id": "C0020498",
"name": "forestier 's disease",
"pos": [
39,
59
]
} |
the patient 's particular circumstances led to the decision to treat the fracture by posterior arthrodesis , though this is not necessarily recommended for all spinal fractures occuring in this disease . | NA | {
"id": "C0016658",
"name": "fracture",
"pos": [
73,
81
]
} | {
"id": "C0080179",
"name": "spinal fractures",
"pos": [
160,
176
]
} |
maintenance of hemoglobin inducibility in somatic cell hybrids of tetraploid ( 2s ) mouse erythroleukemia cells with mouse or human fibroblasts . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
106,
111
]
} | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
132,
143
]
} |
it has previously been reported that friend mouse erythroleukemia ( mel ) cells synthesize hemoglobin when exposed to 2 % dimethylsulfoxide , and that hybrids between mel cells and fibroblasts ( or other nonerythroid cells ) do not synthesize hemoglobin . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
181,
192
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
217,
222
]
} |
in endotoxin shock , a primary mixed coagulopathy develops as an event directly related to the presence of bacterial lipopolysaccharides . | NA | {
"id": "C0014264",
"name": "endotoxin",
"pos": [
3,
12
]
} | {
"id": "C0023810",
"name": "lipopolysaccharides",
"pos": [
117,
136
]
} |
a method for simultaneous measurement of 11-deoxycorticosterone ( doc ) , 18-hydroxy-11-deoxycorticosterone ( 18-oh-doc ) and aldosterone using 1.0-2.0 ml of plasma has been developed . | NA | {
"id": "C0000173",
"name": "18-hydroxy-11-deoxycorticosterone",
"pos": [
74,
107
]
} | {
"id": "C0011710",
"name": "doc",
"pos": [
116,
119
]
} |
some of these mice were given chloramphenicol or thiamphenicol for 7 days after marrow cell transfusion . | NA | {
"id": "C0008168",
"name": "chloramphenicol",
"pos": [
30,
45
]
} | {
"id": "C0039854",
"name": "thiamphenicol",
"pos": [
49,
62
]
} |
it is demonstrated in simulations that , if adjustment for inequality in body weight is to be made by covariance analysis and the comparison is carried out in terms of adjusted means of organ weights thus obtained , the test of significance for an organ weight change can be unbiased , or the chances for detecting spurious effects on organ weights remain at about 5 % and the chances for detecting treatment effects are far above the 5 % irrespective of differences in body weight . | NA | {
"id": "C0005910",
"name": "body",
"pos": [
73,
77
]
} | {
"id": "C0005911",
"name": "differences",
"pos": [
455,
466
]
} |
the urinary concentration of pregnanediol glucuronide in 24-hour collections and in overnight specimens increased 2-fold or more from the day of the midcycle lh peak to the time of predicted ovulation ( 24-48 hour after the lh peak ) in parallel with the rise in serum progesterone concentration . | NA | {
"id": "C0033004",
"name": "pregnanediol",
"pos": [
29,
41
]
} | {
"id": "C0033308",
"name": "progesterone",
"pos": [
269,
281
]
} |
the comparative affinities of other steroids in descending order were : beclomethasone-17 , 21-dipropionate , dexamethasone , beta-methasone , triamcinolone and triamcinolone acetonide . | NA | {
"id": "C0040864",
"name": "triamcinolone",
"pos": [
143,
156
]
} | {
"id": "C0040866",
"name": "triamcinolone acetonide",
"pos": [
161,
184
]
} |
red blood cell 2,3-dpg concentrations were also maintained by hexoses , with mannose being best , dextrose and fructose being similar . | NA | {
"id": "C0019494",
"name": "hexoses",
"pos": [
62,
69
]
} | {
"id": "C0024742",
"name": "mannose",
"pos": [
77,
84
]
} |
red blood cell 2,3-dpg concentrations were also maintained by hexoses , with mannose being best , dextrose and fructose being similar . | NA | {
"id": "C0019494",
"name": "hexoses",
"pos": [
62,
69
]
} | {
"id": "C0016745",
"name": "fructose",
"pos": [
111,
119
]
} |
[ the content of thiamine , its coenzyme form and activity of thiamine diphosphate-dependent enzymes in ontogenesis ] . | NA | {
"id": "C0009235",
"name": "coenzyme",
"pos": [
32,
40
]
} | {
"id": "C0039848",
"name": "thiamine",
"pos": [
62,
70
]
} |
a direct dependence is established between the content of thiamine , its coenzyme form , enzyme of thiamine diphosphate synthesis ( thiamine pyrophosphokinase ) and thiamine diphosphate-containing enzyme ( transketolase ) in the rat liver in different periods of ontogenesis . | NA | {
"id": "C0009235",
"name": "coenzyme",
"pos": [
73,
81
]
} | {
"id": "C0039848",
"name": "thiamine diphosphate",
"pos": [
165,
185
]
} |
membrane ion permeability to sodium cations and phosphate anions , acid resistance and phospholipid composition were studied in erythrocytes frozen and thawed with 15 % glycerol and 10 % solution of polyethylene oxide 1500 . | NA | {
"id": "C0022023",
"name": "ion",
"pos": [
9,
12
]
} | {
"id": "C0003075",
"name": "anions",
"pos": [
58,
64
]
} |
membrane ion permeability to sodium cations and phosphate anions , acid resistance and phospholipid composition were studied in erythrocytes frozen and thawed with 15 % glycerol and 10 % solution of polyethylene oxide 1500 . | NA | {
"id": "C0031603",
"name": "phosphate",
"pos": [
48,
57
]
} | {
"id": "C0003075",
"name": "anions",
"pos": [
58,
64
]
} |
in benign hyperplasia marked beta-glucuronidase and n-acetyl-beta-glucosaminidase activity was seen in the prostatic epithelium whereas the reactions for 5 other glycosidases were only slight or negative . | NA | {
"id": "C0017776",
"name": "beta-glucuronidase",
"pos": [
29,
47
]
} | {
"id": "C0017976",
"name": "glycosidases",
"pos": [
162,
174
]
} |
to date , this would appear to be the third case without clinical tuberous sclerosis in which renal involvement was the sole clinical expression of tuberous sclerosis , and the seventh reported instance of renal failure due to renal angiomyolipomatous hamartomatous transformation . | NA | {
"id": "C0041341",
"name": "tuberous sclerosis",
"pos": [
66,
84
]
} | {
"id": "C0018552",
"name": "hamartomatous",
"pos": [
252,
265
]
} |
it seems that some other humoral factors , e.g . bacterial toxins and endotoxins , formed during the inflammatory process , play their part too . | NA | {
"id": "C0004630",
"name": "bacterial toxins",
"pos": [
49,
65
]
} | {
"id": "C0014264",
"name": "endotoxins",
"pos": [
70,
80
]
} |
the use of a thermoplastic linear polyester polymer orthopaedic tape in the treatment of six horses , one donkey and a bull with a variety of orthopaedic problems requiring immobilisation of a limb is described . | NA | {
"id": "C0032474",
"name": "polyester",
"pos": [
34,
43
]
} | {
"id": "C0032521",
"name": "polymer",
"pos": [
44,
51
]
} |
they possess numerous mitochondria with lamellar and tubular cristae , abundant smooth endoplasmic reticulum , lipofuscin bodies and scanty lipid . | NA | {
"id": "C0023789",
"name": "lipofuscin",
"pos": [
111,
121
]
} | {
"id": "C0023779",
"name": "lipid",
"pos": [
140,
145
]
} |
the morphologic features of the cancer cells clearly indicated that glycoprotein is first synthesized in the golgi complex and fully formed mucoprotein then emerges as membrane-bound glycocalyx in the vesicles budding from the golgi stacks . | NA | {
"id": "C0017968",
"name": "glycoprotein",
"pos": [
68,
80
]
} | {
"id": "C0026714",
"name": "mucoprotein",
"pos": [
140,
151
]
} |
[ effect of the prolonged administration of the atherogenic fractions of lipoproteins on the blood and myocardial lipid picture in rabbits ] . | NA | {
"id": "C0023820",
"name": "lipoproteins",
"pos": [
73,
85
]
} | {
"id": "C0023779",
"name": "lipid",
"pos": [
114,
119
]
} |
content of adrenaline , noradrenaline , dopamine and normetanephrine was estimated by means of trihydroxyindole method in samples of brain and its hypothalamic part from intact , adrenal- and sympathectomized rats within 15 min , 24 and 72 hrs after hemorrhagic stress ( 3 % blood of body weight within 20 min ) . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
11,
21
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
24,
37
]
} |
content of adrenaline , noradrenaline , dopamine and normetanephrine was estimated by means of trihydroxyindole method in samples of brain and its hypothalamic part from intact , adrenal- and sympathectomized rats within 15 min , 24 and 72 hrs after hemorrhagic stress ( 3 % blood of body weight within 20 min ) . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
24,
37
]
} | {
"id": "C0028385",
"name": "normetanephrine",
"pos": [
53,
68
]
} |
antigen , specific for trophoblastic tumor , was isolated from retroplacental blood by means of ion exchange chromatography on deae cellulose , gel filtration on sephadex g-200 , chromatography on hydroxylapatite and cm-cellulose and by preparative isofocusing using ampholines . | NA | {
"id": "C0011050",
"name": "deae cellulose",
"pos": [
127,
141
]
} | {
"id": "C0007648",
"name": "cellulose",
"pos": [
220,
229
]
} |
the initial rate [ v ] versus substrate concentration [ s ] 0 curves had complex shapes for the enzymes from the liver tissue of healthy animals ( especially after extraction of the enzymes by means of buffers with low concentration of k+ ) . | NA | {
"id": "C0026741",
"name": "complex",
"pos": [
73,
80
]
} | {
"id": "C0014442",
"name": "enzymes",
"pos": [
182,
189
]
} |
in single stimulation of hypothalamus the specific radioactivity of nuclear rna was increased in rna-40 degrees fraction than in rna-55 degrees and rna-63 degrees ones . | NA | {
"id": "C0035700",
"name": "nuclear rna",
"pos": [
68,
79
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
148,
151
]
} |
in order to develop a tolerance to experimental atherosclerosis newborn rabbits were immunized with various fractions of atherogenic lipoproteins ( lipoproteins of low density , lipoproteins of very low density and total fraction of these lipoproteins ) , isolated from blood serum of adult rabbits with experimental hypercholesterolemia . | NA | {
"id": "C0023825",
"name": "lipoproteins",
"pos": [
133,
145
]
} | {
"id": "C0023820",
"name": "lipoproteins",
"pos": [
239,
251
]
} |
when putting these animals on a food ration with the calcium and phosphorus ratio of 1:1 the concentration of these elements in the blood quickly returns back to normal , while renal calcinosis continues for the whole period of observation ( 7 months ) . | NA | {
"id": "C0031705",
"name": "phosphorus",
"pos": [
65,
75
]
} | {
"id": "C0013879",
"name": "elements",
"pos": [
116,
124
]
} |
to a varying extent these are changed by : the addition of divers soluble polymers , the action of enzymes , the presence of various salt ions , centrifugation , agglomeration at low ionic strength , complex coacervation with cationic polymers , and the interaction with different kinds of antibodies . | NA | {
"id": "C0022023",
"name": "ions",
"pos": [
138,
142
]
} | {
"id": "C0007447",
"name": "cationic",
"pos": [
226,
234
]
} |
of the fractionated proteins albumin contained mehp in amounts from less than 3 to 290 microgram/g . | NA | {
"id": "C0033684",
"name": "proteins",
"pos": [
20,
28
]
} | {
"id": "C0001924",
"name": "albumin",
"pos": [
29,
36
]
} |
psoralen photosensitization of l 1210 cells has a strong effect on dna and rna syntheses and this result appears connected with the psoralen photobinding to dna . | NA | {
"id": "C0000702",
"name": "a",
"pos": [
4,
5
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
157,
160
]
} |
effects of ecdysterone and the juvenile hormone analogue methoprene on protein , rna and dna synthesis in wing discs of calliphora vicina . | NA | {
"id": "C0022439",
"name": "juvenile hormone",
"pos": [
31,
47
]
} | {
"id": "C0025674",
"name": "methoprene",
"pos": [
57,
67
]
} |
[ effect of adrenaline and noradrenaline on the state of the skin microcirculation at different age periods ] . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
12,
22
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
27,
40
]
} |
it was determined in watering experiments that a starting concentration of 0.01-0.02 % peracetic acid was required in order to guarantee the sterility of water and water-bottle for a duration of one week . | NA | {
"id": "C0043047",
"name": "watering",
"pos": [
21,
29
]
} | {
"id": "C0359299",
"name": "sterility",
"pos": [
141,
150
]
} |
63 cases of extraintestinal amoebiasis , 17 cases of intestinal amoebiasis , and 25 selected control persons were examined for serum antibodies to antigen from e. histolytica using the counter-immunoelectrophoresis , the complement fixation test , the indirect haemagglutination test and the latex agglutination test . | NA | {
"id": "C0002438",
"name": "amoebiasis",
"pos": [
28,
38
]
} | {
"id": "C0013370",
"name": "intestinal amoebiasis",
"pos": [
53,
74
]
} |
on the other hand , there are persons with no symptoms of amoebiasis who have antibodies in two tests , among them sometimes the counter-immunoelectrophoresis , with levels corresponding to those of intestinal or extra-intestinal amoebiasis . | NA | {
"id": "C0002438",
"name": "amoebiasis",
"pos": [
58,
68
]
} | {
"id": "C0013370",
"name": "intestinal amoebiasis",
"pos": [
219,
240
]
} |
in dogs and squirrels which in natural environment reveal high level of muscle activity , the content of norepinephrine in the brain stem and total content of epinephrine and norepinephrine in the suprarenals are lower than in rabbits and albino rats which are characterized by a lower muscle activity . | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
108,
119
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
175,
189
]
} |
one of the pressing tasks in the study of local nonsusceptibility to infectious diseases and immunochemical analysis of the external secretion is recording of the level of various forms of the secretory iga ( siga ) and of the secretory component ( sc ) in various biological fluids . | NA | {
"id": "C0020838",
"name": "secretory iga",
"pos": [
193,
206
]
} | {
"id": "C0036538",
"name": "secretory",
"pos": [
227,
236
]
} |
it was shown that the antisera to the whole molecule of siga and sc are of no use . | NA | {
"id": "C0020838",
"name": "siga",
"pos": [
56,
60
]
} | {
"id": "C0036538",
"name": "sc",
"pos": [
65,
67
]
} |
on the basis of a new method of purification of free sc and technology of preparation of monospecific antisera capable of separation of siga and free sc there were obtained diagnostic antisera for the quantitative recording and differentiation of various forms of iga and sc in biological fluids . | NA | {
"id": "C0020838",
"name": "siga",
"pos": [
136,
140
]
} | {
"id": "C0036538",
"name": "sc",
"pos": [
272,
274
]
} |
a reliable measurement of the siga and sc concentration in some external secretion was carried out with the aid of the mentioned preparations without any complicated chromatographic experiments . | NA | {
"id": "C0020838",
"name": "siga",
"pos": [
30,
34
]
} | {
"id": "C0036538",
"name": "sc",
"pos": [
39,
41
]
} |
the nature of antibodies was identified in coombs ' test , using monospecific antisera to alpha-chain and to the secretory component . | NA | {
"id": "C0003241",
"name": "antibodies",
"pos": [
14,
24
]
} | {
"id": "C0020960",
"name": "antisera",
"pos": [
78,
86
]
} |
investigations concerning a possible influence of thyroid disease and function on the risk for breast cancer have given contradictory results -- although a slight hypothyroidism was repeatedly suggested and supported by increased thyrotropin concentrations and exaggerated trh-responses . | NA | {
"id": "C0040128",
"name": "thyroid disease",
"pos": [
50,
65
]
} | {
"id": "C0020676",
"name": "hypothyroidism",
"pos": [
163,
177
]
} |
it is shown that in the rat , zinc is absorbed from excisional wounds into serum , from various locally applied zinc oxide preparations as well as from zinc peroxide and zinc sulphate . | NA | {
"id": "C0043481",
"name": "zinc",
"pos": [
30,
34
]
} | {
"id": "C0078794",
"name": "zinc sulphate",
"pos": [
170,
183
]
} |
cortisol , corticosterone , epinephrine and norepinephrine have been identified for the first time in two adrenal cysts removed from patients without endocrine dysfunction . | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
28,
39
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
44,
58
]
} |
the effects of lh , adrenaline and noradrenaline on testicular blood flow and plasma testosterone concentrations in anaesthetized rats . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
20,
30
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
35,
48
]
} |
[ peritonitis caused by perforation of the small intestine in free peritoneum as a 1st sign of crohn 's disease ] . | NA | {
"id": "C0031154",
"name": "peritonitis",
"pos": [
2,
13
]
} | {
"id": "C0031142",
"name": "peritoneum",
"pos": [
67,
77
]
} |
a new ria method for the detection of circulating immune complexes and antibodies arising in the course of viral hepatitis is described . | NA | {
"id": "C0003313",
"name": "circulating immune complexes",
"pos": [
38,
66
]
} | {
"id": "C0003241",
"name": "antibodies",
"pos": [
71,
81
]
} |
it involves the use of 125i-labeled antibodies and foresees the possibility of employing immune complex-coated polypropylene tubes . | NA | {
"id": "C0003241",
"name": "antibodies",
"pos": [
36,
46
]
} | {
"id": "C0003313",
"name": "immune complex",
"pos": [
89,
103
]
} |
both studies showed that the control ligations produced a large uniform area of ischemia or infarction that was greatly reduced or prevented by immediate treatment with beta-histine . | NA | {
"id": "C0022116",
"name": "ischemia",
"pos": [
80,
88
]
} | {
"id": "C0021308",
"name": "infarction",
"pos": [
92,
102
]
} |
the coagulation factors pp % ( factors ii+iv ) , factor ix and factor x were determined in infants born by mothers receiving anticoagulants . | NA | {
"id": "C0005789",
"name": "coagulation factors",
"pos": [
4,
23
]
} | {
"id": "C0006675",
"name": "factors",
"pos": [
31,
38
]
} |
the coagulation factors pp % ( factors ii+iv ) , factor ix and factor x were determined in infants born by mothers receiving anticoagulants . | NA | {
"id": "C0005789",
"name": "coagulation factors",
"pos": [
4,
23
]
} | {
"id": "C0015491",
"name": "factor ix",
"pos": [
49,
58
]
} |
the coagulation factors pp % ( factors ii+iv ) , factor ix and factor x were determined in infants born by mothers receiving anticoagulants . | NA | {
"id": "C0005789",
"name": "coagulation factors",
"pos": [
4,
23
]
} | {
"id": "C0015518",
"name": "factor x",
"pos": [
63,
71
]
} |
a preliminary investigation with infants and children showed that the inhibitory process is present , though variable , in children as young as 6 weeks olds . | NA | {
"id": "C0008059",
"name": "children",
"pos": [
45,
53
]
} | {
"id": "C0728836",
"name": "children",
"pos": [
123,
131
]
} |
[ sorption activity of medicinal charcoal . ii . effects of steam activation on the sorption activity of carbo medicinalis ] . | NA | {
"id": "C0001275",
"name": "medicinal charcoal",
"pos": [
23,
41
]
} | {
"id": "C0007955",
"name": "carbo",
"pos": [
105,
110
]
} |
those with respiratory tract infection experienced more febrile reactions during periods with infection than during periods without . | NA | {
"id": "C0035243",
"name": "respiratory tract infection",
"pos": [
11,
38
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
94,
103
]
} |
there was a significant relation between the urinary excretions of albumin and protein in the patients with febrile proteinuria . | NA | {
"id": "C0001924",
"name": "albumin",
"pos": [
67,
74
]
} | {
"id": "C0033684",
"name": "protein",
"pos": [
116,
123
]
} |
heparin was given i.v . to subjects with type iv hyperlipoproteinaemia who had only ordinary pre-beta lipoproteins and no late pre-beta lipoproteins ( lp-beta ) in their very low density lipoproteins ( vldl , d less than 1.006 ) upon agarose gel lipoprotein electrophoresis . | NA | {
"id": "C0023825",
"name": "pre-beta lipoproteins",
"pos": [
93,
114
]
} | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
246,
257
]
} |
various aspects of chondrodystrophic dwarfism and basilar impression are discussed in relation to the neurological symptomatology , and the question of whether , in general , more attention should be given to the cranio-cervical region , is raised . | NA | {
"id": "C0001080",
"name": "chondrodystrophic",
"pos": [
19,
36
]
} | {
"id": "C0013336",
"name": "dwarfism",
"pos": [
37,
45
]
} |
the alpha-agonist action of epinephrine and norepinephrine reduced cyclic amp levels stimulated by beta-agonist or by adenosine ; | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
28,
39
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
44,
58
]
} |
in group 1 patients ( anterior uveitis syndrome ) topical cortisone drops or ointment will control the disease . | NA | {
"id": "C0039082",
"name": "syndrome",
"pos": [
39,
47
]
} | {
"id": "C0012634",
"name": "disease",
"pos": [
103,
110
]
} |
a survey of the use of radioisotopes for research into the vitreous and the zonule is presented . gamma-rays emitting isotopes are useful for the investigation of transport and diffusion of substances , while 3h-thymidine is the substance of choice for the investigation of cell kinetics . | NA | {
"id": "C0034595",
"name": "radioisotopes",
"pos": [
23,
36
]
} | {
"id": "C0022262",
"name": "isotopes",
"pos": [
118,
126
]
} |
the surgical treatment of arrhythmias related to the preexcitation syndromes remains the model of electrophysiologic surgery . | NA | {
"id": "C0003811",
"name": "arrhythmias",
"pos": [
26,
37
]
} | {
"id": "C0032915",
"name": "preexcitation syndromes",
"pos": [
53,
76
]
} |
when compared with supraventricular tachycardia due to a-v nodal reentry , clinical findings suggestive of a concealed bypass tract included : ( 1 ) p wave following the qrs complex ( 12 of 12 versus 12 of 40 ) , ( 2 ) negative p wave in lead i during the tachycardia , and ( 3 ) bundle branch block aberration during the tachycardia ( 8 of 12 versus 3 of 40 ) . | NA | {
"id": "C0039240",
"name": "supraventricular tachycardia",
"pos": [
19,
47
]
} | {
"id": "C0039231",
"name": "tachycardia",
"pos": [
322,
333
]
} |
a 60-year-old woman , 20 years post-menopausal , who had deforming rheumatoid arthritis of 7 years ' duration and sjogren 's syndrome of 1 year 's duration , had had postmenopausal bleeding for a month prior to admission to the hospital . | NA | {
"id": "C0003873",
"name": "rheumatoid",
"pos": [
67,
77
]
} | {
"id": "C1527336",
"name": "sjogren 's syndrome",
"pos": [
114,
133
]
} |
a review of the literature disclosed several cases of parotitis , either recurrent or postimmunization , but the preparotitis immune status of the patient was unknown or the cause of the mumps was not verified . | NA | {
"id": "C0030583",
"name": "parotitis",
"pos": [
54,
63
]
} | {
"id": "C0026780",
"name": "mumps",
"pos": [
187,
192
]
} |
inflammatory bowel disease ( ibd ) patients in the united states of america ( usa ) and czechoslovakia ( cssr ) were categorized by clinical , pathological , and radiological criteria as having crohn 's disease ( cd ) or ulcerative colitis ( uc ) and were tested with five skin test antigens [ candida , mumps , purified protein derivative ( ppd ) , streptokinase-streptodornase ( sk-sd ) , and trichophytin ] at two different dilutions in an attempt to elicit some evidence of anergy . | NA | {
"id": "C0021390",
"name": "inflammatory bowel disease",
"pos": [
0,
26
]
} | {
"id": "C0010346",
"name": "crohn 's disease",
"pos": [
194,
210
]
} |
the prevalence of urinary antibody-coated bacteria ( acb ) , suggesting renal bacteriuria , was studied in three groups of patients : inpatients whose physicians suspected urinary tract infections , asymptomatic outpatients with neurogenic bladders but without urethral catheters , and asymptomatic inpatients with indwelling urethral catheters . | NA | {
"id": "C0004659",
"name": "bacteriuria",
"pos": [
78,
89
]
} | {
"id": "C0042029",
"name": "urinary tract infections",
"pos": [
172,
196
]
} |
from a study of the determinants of a-ii pressor responsiveness in normal gravid women , it appears likely that the loss of resistance to a-ii is principally unrelated to plasma renin activity or to plasma a-ii levels . | NA | {
"id": "C0003018",
"name": "a-ii",
"pos": [
36,
40
]
} | {
"id": "C0003009",
"name": "a-ii",
"pos": [
206,
210
]
} |
these 126 subjects were at risk for delivery of a premature infant because of premature labor of fetomaternal disease necessitating intervention . | NA | {
"id": "C0151526",
"name": "delivery",
"pos": [
36,
44
]
} | {
"id": "C0022876",
"name": "premature labor",
"pos": [
78,
93
]
} |
pregnenolone , 17-hydroxypregnenolone , 17-hydroxyprogesterone , dehydroepiandrosterone , and testosterone were also secreted , but in quantities which were one third to one sixth the amount of androstenedione . | NA | {
"id": "C0373704",
"name": "pregnenolone",
"pos": [
0,
12
]
} | {
"id": "C0376260",
"name": "17-hydroxypregnenolone",
"pos": [
15,
37
]
} |
radiation and gynecologic oncologists agree that pelvic irradiation in the presence of pelvic inflammatory disease , parametritis , or pyometra can be catastrophic . | NA | {
"id": "C0242172",
"name": "pelvic",
"pos": [
49,
55
]
} | {
"id": "C0030455",
"name": "parametritis",
"pos": [
117,
129
]
} |
the malocclusion sample was divided into groups according to molar displacement : 214 neutroclusion cases ( group 2 ) , 624 distoclusion cases ( group 3 ) , and 36 mesioclusion cases ( group 4 ) . | NA | {
"id": "C0024636",
"name": "malocclusion",
"pos": [
4,
16
]
} | {
"id": "C0399523",
"name": "neutroclusion",
"pos": [
86,
99
]
} |
in both models , an increased fluid transport was observed in the phase of gallstone induction and a return to normal after stones were formed . | NA | {
"id": "C0008350",
"name": "gallstone",
"pos": [
75,
84
]
} | {
"id": "C0006736",
"name": "stones",
"pos": [
124,
130
]
} |
the most common malignant tumor was lymphoma ( 67 per cent ) followed by adenocarcinoma ( 16 per cent ) , carcinoid ( 10 per cent ) , and leiomyosarcoma ( 3 per cent ) . | NA | {
"id": "C0001418",
"name": "adenocarcinoma",
"pos": [
73,
87
]
} | {
"id": "C0007095",
"name": "carcinoid",
"pos": [
106,
115
]
} |
in men serum insulin- , gh- and total corticoid levels correlate positive significant with glucose and cholesterol levels , relative body weight and blood pressure , which possibly shows , that these hormones may play a role in the development of degenerative heart and blood vessel diseases . | NA | {
"id": "C0001617",
"name": "corticoid",
"pos": [
38,
47
]
} | {
"id": "C0019932",
"name": "hormones",
"pos": [
200,
208
]
} |
the antibiotics tested were five aminoglycosides ( neomycin , gentamicin , streptomycin , dihydrostreptomycin and kanamycin ) , tetracycline and oxytetracycline , polymyxins b and e , penicillins g and v , cephradine , cephaloridine , erythromycin , lincomycin , and clindamycin . | NA | {
"id": "C0002556",
"name": "aminoglycosides",
"pos": [
33,
48
]
} | {
"id": "C0017436",
"name": "gentamicin",
"pos": [
62,
72
]
} |
the antibiotics tested were five aminoglycosides ( neomycin , gentamicin , streptomycin , dihydrostreptomycin and kanamycin ) , tetracycline and oxytetracycline , polymyxins b and e , penicillins g and v , cephradine , cephaloridine , erythromycin , lincomycin , and clindamycin . | NA | {
"id": "C0002556",
"name": "aminoglycosides",
"pos": [
33,
48
]
} | {
"id": "C0038425",
"name": "streptomycin",
"pos": [
97,
109
]
} |
the antibiotics tested were five aminoglycosides ( neomycin , gentamicin , streptomycin , dihydrostreptomycin and kanamycin ) , tetracycline and oxytetracycline , polymyxins b and e , penicillins g and v , cephradine , cephaloridine , erythromycin , lincomycin , and clindamycin . | NA | {
"id": "C0023726",
"name": "lincomycin",
"pos": [
250,
260
]
} | {
"id": "C0008947",
"name": "clindamycin",
"pos": [
267,
278
]
} |
the histoenzymological and ultrastructural study of a haemangipericytoma with the clinical and histological characteristics of malignancy led to the identification within the tumour , in addition to pericytes and more differentiated cells , fibroblastic or muscular , of younger cells . | NA | {
"id": "C0016030",
"name": "fibroblastic",
"pos": [
241,
253
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
279,
284
]
} |
the mean +/- se shunt fraction was 20 +/- 1.2 per cent in patients with alveolar proteinosis compared to 8.9 +/- 0.5 per cent in other groups of patients with diffuse lung disease ( p less than 0.001 ) . | NA | {
"id": "C0034050",
"name": "alveolar",
"pos": [
72,
80
]
} | {
"id": "C0024115",
"name": "lung disease",
"pos": [
167,
179
]
} |
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