text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
because those sera which had antibody had antibody to several viruses , it was suggested that the use of the micro-serum neutralization test with a few bovine viruses which are widespread in the bovine population should be satisfactory to detect fcs which was contaminated with postcolostral bovine serum . | NA | {
"id": "C0003241",
"name": "antibody",
"pos": [
29,
37
]
} | {
"id": "C0003253",
"name": "antibody",
"pos": [
42,
50
]
} |
nearly every culture tested under the anaerobic atmosphere was inhibited by one of the branched-chain amino acids , leucine , valine , or isoleucine . | NA | {
"id": "C0002521",
"name": "branched-chain amino acids",
"pos": [
87,
113
]
} | {
"id": "C0023401",
"name": "leucine",
"pos": [
141,
148
]
} |
nearly every culture tested under the anaerobic atmosphere was inhibited by one of the branched-chain amino acids , leucine , valine , or isoleucine . | NA | {
"id": "C0002521",
"name": "branched-chain amino acids",
"pos": [
87,
113
]
} | {
"id": "C0042285",
"name": "valine",
"pos": [
126,
132
]
} |
nearly every culture tested under the anaerobic atmosphere was inhibited by one of the branched-chain amino acids , leucine , valine , or isoleucine . | NA | {
"id": "C0002521",
"name": "branched-chain amino acids",
"pos": [
87,
113
]
} | {
"id": "C0022192",
"name": "isoleucine",
"pos": [
138,
148
]
} |
an increase in adenosine 3',5'-monophosphate ( cyclic amp ) in rat mast cells , achieved by stimulating the cells with prostaglandin e ( 1 ) , by preventing cyclic amp breakdown with aminophylline , or by adding exogenous dibutyryl cyclic amp , prevented complement-mediated cytolysis as assessed by both histamine relea... | NA | {
"id": "C0001455",
"name": "cyclic amp",
"pos": [
47,
57
]
} | {
"id": "C0012054",
"name": "dibutyryl cyclic amp",
"pos": [
222,
242
]
} |
modifications of epinephrine , norepinephrine , blood lipid fractions and the cardiovascular system produced by noise in an industrial medium . | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
17,
28
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
31,
45
]
} |
it would appear that the conditions of denaturation used ( 99 % dimethyl sulfoxide at 26 c , and reaction with 1.1 m formaldehyde for 10 min at 60 c ) do not equally denature parainfluenza virus rna and other rnas , such as cellular rrna , 45s rrna precursor , and r17 rna . | NA | {
"id": "C0035701",
"name": "rrna",
"pos": [
233,
237
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
269,
272
]
} |
this cell killing was used to develop a plaque assay for trager duck spleen necrosis virus ( tdsnv ) on duck embryo fibroblasts . | NA | {
"id": "C0007634",
"name": "cell",
"pos": [
5,
9
]
} | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
116,
127
]
} |
according to this model , phage-neutralizing antibodies attach anywhere along the length of the phage and allow the phage to penetrate only up to the first bound antibody molecule . | NA | {
"id": "C0475463",
"name": "neutralizing antibodies",
"pos": [
32,
55
]
} | {
"id": "C0003241",
"name": "antibody",
"pos": [
162,
170
]
} |
the virus-induced proteins within the cell were identified either as free proteins or in association with membranous material , including the plasma membrane . | NA | {
"id": "C0042736",
"name": "virus",
"pos": [
4,
9
]
} | {
"id": "C0033684",
"name": "proteins",
"pos": [
74,
82
]
} |
other ribonucleoside and deoxyribonucleoside triphosphates as well as alpha , beta-methylene- and beta , gamma-methylene-atp and alpha , beta-methylene-adp are able to partially substitute for atp in stimulating the rate of dna synthesis with the cytoplasmic dna polymerase ( dna nucleotidyltransferase , ec 2.7.7.7 ) fr... | NA | {
"id": "C0012892",
"name": "dna polymerase",
"pos": [
259,
273
]
} | {
"id": "C0012882",
"name": "dna",
"pos": [
276,
279
]
} |
antisera to the enzyme and to procollagen have been prepared and have been used to characterize the enzyme , the enzymatically excised peptides , and the enzyme-peptide complex in reaction mixtures . | NA | {
"id": "C0014442",
"name": "enzyme",
"pos": [
16,
22
]
} | {
"id": "C0026741",
"name": "enzyme",
"pos": [
154,
160
]
} |
however , it is theoretically possible that such tests may respond not only to factors ( i.e. , proteins that join and leave a ribosome during its cycle ) , but also to true ribosomal proteins that may have been extracted . | NA | {
"id": "C0033684",
"name": "proteins",
"pos": [
96,
104
]
} | {
"id": "C0035552",
"name": "ribosomal proteins",
"pos": [
174,
192
]
} |
tests with both systems , applied to extracts of different classes of particles , suggest that high salt does extract both initiation factors and essential ribosomal proteins . | NA | {
"id": "C0030943",
"name": "initiation",
"pos": [
123,
133
]
} | {
"id": "C0035552",
"name": "ribosomal proteins",
"pos": [
156,
174
]
} |
one of the new glycoprotein complexes was shown to contain two of the three species of membrane glycoproteins . | NA | {
"id": "C0017968",
"name": "glycoprotein",
"pos": [
15,
27
]
} | {
"id": "C0025248",
"name": "membrane glycoproteins",
"pos": [
87,
109
]
} |
release of lysosomal enzymes is inhibited by epinephrine and adenosine 3',5'-monophosphate ( cyclic amp ) , but not by phenylephrine or adenosine 5'-monophosphate . | NA | {
"id": "C0001455",
"name": "cyclic amp",
"pos": [
93,
103
]
} | {
"id": "C0001413",
"name": "adenosine 5",
"pos": [
136,
147
]
} |
vascular hyperresponsiveness to small quantities of free angiotensin could not be invoked to explain the hypertension , for there was no significant difference between mock-immunized hypertensive animals , and those remaining normotensive , regarding pressor sensitivity to intravenous ai , aii , renin , and norepinephr... | NA | {
"id": "C0003018",
"name": "angiotensin",
"pos": [
57,
68
]
} | {
"id": "C0003006",
"name": "ai",
"pos": [
291,
293
]
} |
vascular hyperresponsiveness to small quantities of free angiotensin could not be invoked to explain the hypertension , for there was no significant difference between mock-immunized hypertensive animals , and those remaining normotensive , regarding pressor sensitivity to intravenous ai , aii , renin , and norepinephr... | NA | {
"id": "C0003018",
"name": "angiotensin",
"pos": [
57,
68
]
} | {
"id": "C0003009",
"name": "aii",
"pos": [
291,
294
]
} |
the capsid and two membrane proteins of sindbis virus , grown in chicken cells , contain 0.03 to 0.1 mol of phosphate per mol of protein . | NA | {
"id": "C0025252",
"name": "membrane proteins",
"pos": [
19,
36
]
} | {
"id": "C0033684",
"name": "protein",
"pos": [
129,
136
]
} |
new membrane proteins synthesized at times greater than 6 min after infection appear to be distinct from those of the host , and new proteins of the outer membrane are different from those of the inner . | NA | {
"id": "C0025252",
"name": "membrane proteins",
"pos": [
4,
21
]
} | {
"id": "C0033684",
"name": "proteins",
"pos": [
133,
141
]
} |
some studies of the active intermediates formed in the microsomal metabolism of cyclophosphamide and isophosphamide . | NA | {
"id": "C0010583",
"name": "cyclophosphamide",
"pos": [
80,
96
]
} | {
"id": "C0020823",
"name": "isophosphamide",
"pos": [
101,
115
]
} |
prostaglandin-mediated action of intrauterine devices : f-prostaglandins in the uterine horns of pregnant rabbits with unilateral intrauterine devices . | NA | {
"id": "C0033554",
"name": "prostaglandin",
"pos": [
0,
13
]
} | {
"id": "C0033561",
"name": "f-prostaglandins",
"pos": [
56,
72
]
} |
triglycerides containing unsaturated fatty acids are eluted more rapidly than their saturated homologs , one c-c double bond being equivalent to -1.42 fatty acid carbon atoms . | NA | {
"id": "C0015690",
"name": "unsaturated fatty acids",
"pos": [
25,
48
]
} | {
"id": "C0015684",
"name": "fatty acid",
"pos": [
151,
161
]
} |
mannanase digestion of two of the mannans yielded polysaccharide residues that were unbranched ( 1 -- > 6 ) -linked polymers , thus establishing the structural relationship between these mannans and that from s. cerevisiae . | NA | {
"id": "C0032594",
"name": "polysaccharide",
"pos": [
50,
64
]
} | {
"id": "C0024727",
"name": "mannans",
"pos": [
187,
194
]
} |
the messenger ribonucleic acid ( mrna ) pattern of log-phase and sporulating cells of bacillus subtilis has been analyzed by deoxyribonucleic acid ( dna ) -rna hybrid studies with the complementary-strand fragments of dna . | NA | {
"id": "C0035696",
"name": "messenger ribonucleic acid",
"pos": [
4,
30
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
156,
159
]
} |
as a result of this degradation , both the lipopolysaccharide and simple protein fragments retained a part of the lipid moiety . | NA | {
"id": "C0023810",
"name": "lipopolysaccharide",
"pos": [
43,
61
]
} | {
"id": "C0023767",
"name": "a",
"pos": [
103,
104
]
} |
it is suggested that the presence of these degradation products is one of the main causes of the heterogeneity of endotoxin and lipopolysaccharide preparations . | NA | {
"id": "C0014264",
"name": "endotoxin",
"pos": [
114,
123
]
} | {
"id": "C0023810",
"name": "lipopolysaccharide",
"pos": [
128,
146
]
} |
studies on the binding of carbamyl phosphate to nitrogenase and each of its two components ( azoferredoxin and molybdoferredoxin ) indicated that optimal binding was obtained only in the presence of an operating nitrogenase system . | NA | {
"id": "C0085544",
"name": "azoferredoxin",
"pos": [
93,
106
]
} | {
"id": "C0028174",
"name": "nitrogenase",
"pos": [
212,
223
]
} |
interaction of the first ( c1 ) , the second ( c2 ) and the fourth ( c4 ) component of complement with different preparations of bacterial lipopolysaccharides and with lipid a . | NA | {
"id": "C0023810",
"name": "lipopolysaccharides",
"pos": [
139,
158
]
} | {
"id": "C0023767",
"name": "lipid a",
"pos": [
168,
175
]
} |
whereas cadmium treatment decreased the level of hepatic glycogen , the concentration of blood glucose and urea was significantly elevated by this heavy metal . | NA | {
"id": "C0006632",
"name": "cadmium",
"pos": [
8,
15
]
} | {
"id": "C0347988",
"name": "heavy metal",
"pos": [
147,
158
]
} |
discontinuation of the heavy metal treatment for 28 days , in rats previously injected with cadmium for 45 days , failed to restore the observed biochemical alterations in hepatic and renal carbohydrate metabolism to control values . | NA | {
"id": "C0347988",
"name": "heavy metal",
"pos": [
23,
34
]
} | {
"id": "C0006632",
"name": "cadmium",
"pos": [
92,
99
]
} |
evidence indicates that cadmium augments the glucose-synthesizing capacity of liver and kidney cortex and that various metabolic changes persist even after a 4-week period of withdrawal from exposure to the heavy metal . | NA | {
"id": "C0006632",
"name": "cadmium",
"pos": [
24,
31
]
} | {
"id": "C0347988",
"name": "heavy metal",
"pos": [
207,
218
]
} |
the chief complications observed in a series of 241 drug abuse patients were aspiration pneumonitis ( 12.9 percent ) , pulmonary edema ( 10.0 percent ) , and pneumonia ( 7.5 percent ) . | NA | {
"id": "C0032290",
"name": "aspiration pneumonitis",
"pos": [
77,
99
]
} | {
"id": "C0032285",
"name": "pneumonia",
"pos": [
158,
167
]
} |
imbalance in ornithine metabolism in hepatomas of different growth rates as expressed in behavior of l-ornithine:2-oxoacid aminotransferase ( ornithine transaminase , ec 2.6.1.13 ) . | NA | {
"id": "C0002594",
"name": "aminotransferase",
"pos": [
123,
139
]
} | {
"id": "C0029278",
"name": "ornithine",
"pos": [
142,
151
]
} |
we have been unable to show that either taking oral contraceptives shortly before pregnancy or a high vitamin a level during the first trimester of pregnancy , comparable to that of a woman taking oral contraceptives , has any detrimental effect on the outcome of pregnancy . | NA | {
"id": "C0032961",
"name": "pregnancy",
"pos": [
82,
91
]
} | {
"id": "C0032979",
"name": "first trimester",
"pos": [
129,
144
]
} |
these studies show that after 96 h of hyperoxia the lung has recovered its ability to synthesize protein including protein in the surface-active fraction and that these biochemical changes are associated with consistent ultrastructural alterations in the granular pneumocyte . | NA | {
"id": "C0033684",
"name": "protein",
"pos": [
97,
104
]
} | {
"id": "C0025252",
"name": "protein",
"pos": [
115,
122
]
} |
when ouabain was present , na ( + ) influx was higher with k ( + ) ions externally than with other cations externally . | NA | {
"id": "C0022023",
"name": "ions",
"pos": [
67,
71
]
} | {
"id": "C0007447",
"name": "cations",
"pos": [
99,
106
]
} |
agarose beads were coupled via cyanogen bromide to human serum albumin so as to contain 30-50 mg of albumin/g wet wt . | NA | {
"id": "C0304925",
"name": "human serum albumin",
"pos": [
51,
70
]
} | {
"id": "C0001924",
"name": "albumin",
"pos": [
100,
107
]
} |
when whole blood was passed over agarose-albumin beads , bilirubin was removed , calcium and magnesium fell slightly , but red cells , white cells , platelets , clotting factors , and a variety of electrolytes and proteins were substantially unchanged . | NA | {
"id": "C0001924",
"name": "albumin",
"pos": [
41,
48
]
} | {
"id": "C0033684",
"name": "proteins",
"pos": [
214,
222
]
} |
when whole blood was passed over agarose-albumin beads , bilirubin was removed , calcium and magnesium fell slightly , but red cells , white cells , platelets , clotting factors , and a variety of electrolytes and proteins were substantially unchanged . | NA | {
"id": "C0006675",
"name": "calcium",
"pos": [
81,
88
]
} | {
"id": "C0005789",
"name": "clotting factors",
"pos": [
161,
177
]
} |
to examine whether beta-adrenergic stimulation causes vasopressin release by a direct cerebral action , iso was infused into the carotid artery in a dose estimated to equal the amount of catecholamine reaching the cerebral circulation in the i.v . studies . | NA | {
"id": "C0022245",
"name": "iso",
"pos": [
104,
107
]
} | {
"id": "C0007412",
"name": "catecholamine",
"pos": [
187,
200
]
} |
the results therefore indicate that iso stimulates vasopressin release by altering baroreceptor tone rather than by a direct central or depressor effect of the catecholamine . | NA | {
"id": "C0022245",
"name": "iso",
"pos": [
36,
39
]
} | {
"id": "C0007412",
"name": "catecholamine",
"pos": [
160,
173
]
} |
fasting levels of threonine , glycine , cystine , methionine , isoleucine , tryptophan , and arginine , but not of the other amino acids , increased with the increment in input , although the levels were generally lower than normal . | NA | {
"id": "C0017890",
"name": "glycine",
"pos": [
30,
37
]
} | {
"id": "C0002520",
"name": "amino acids",
"pos": [
125,
136
]
} |
halogenated analogues such as 5-fluorocytidine and 5-bromo-2'-deoxycytidine also exhibited substrate activity , with maximum velocities greater than that of the physiologic substrates cytidine and deoxycytidine . | NA | {
"id": "C0006232",
"name": "5-bromo-2",
"pos": [
51,
60
]
} | {
"id": "C0011485",
"name": "deoxycytidine",
"pos": [
197,
210
]
} |
halogenated analogues such as 5-fluorocytidine and 5-bromo-2'-deoxycytidine also exhibited substrate activity , with maximum velocities greater than that of the physiologic substrates cytidine and deoxycytidine . | NA | {
"id": "C0010715",
"name": "cytidine",
"pos": [
38,
46
]
} | {
"id": "C0011485",
"name": "deoxycytidine",
"pos": [
197,
210
]
} |
immunologically identical 20s and 9s igm proteins were isolated from the serum and the addition in vitro of either the patient 's albumin or albumin isolated from normal serum was shown to reconstitute the 23s and 12s boundaries . | NA | {
"id": "C0033684",
"name": "proteins",
"pos": [
41,
49
]
} | {
"id": "C0001924",
"name": "albumin",
"pos": [
141,
148
]
} |
the l'ec protein has the characteristics of an antibody against aggregated albumin , which also has reactivity with native ( monomer ) albumin . | NA | {
"id": "C0033684",
"name": "protein",
"pos": [
9,
16
]
} | {
"id": "C0001924",
"name": "albumin",
"pos": [
135,
142
]
} |
restoration of growth by human growth hormone ( roos ) in hypopituitary dwarfs immunized by other human growth hormone preparations : clinical and immunological studies . | NA | {
"id": "C0169964",
"name": "human growth hormone",
"pos": [
25,
45
]
} | {
"id": "C0037663",
"name": "human growth hormone preparations",
"pos": [
98,
131
]
} |
the increase in igg levels was not paralleled by a demonstrable antibody activity against lipid a , srbc , and lps . | NA | {
"id": "C0023767",
"name": "lipid a",
"pos": [
90,
97
]
} | {
"id": "C0023810",
"name": "lps",
"pos": [
111,
114
]
} |
the class of immunoglobulin on lightly labeled cells was also studied and it was found that [ ( 125 ) i ] anti-igm antibodies bound to an extent approaching the [ ( 125 ) i ] anti-fab binding , while [ ( 125 ) i ] anti-igg ( 2a+2b ) antibodies gave much less binding . | NA | {
"id": "C0021017",
"name": "class",
"pos": [
4,
9
]
} | {
"id": "C0003241",
"name": "antibodies",
"pos": [
233,
243
]
} |
the phorbol ester 12-0-tetradecanoyl-phorbol-13-acetate , a potent tumor-promoting agent , caused irreversible platelet aggregation when more than 0.02 microm was stirred with human citrated or heparinized platelet-rich plasma ( prp ) . | NA | {
"id": "C0031586",
"name": "phorbol ester",
"pos": [
4,
17
]
} | {
"id": "C0039654",
"name": "tetradecanoyl-phorbol",
"pos": [
23,
44
]
} |
oral contraceptives : ethinyl estradiol binds with higher affinity than mestranol to macromolecules from the sites of anti-fertility action . | NA | {
"id": "C0015011",
"name": "ethinyl estradiol",
"pos": [
22,
39
]
} | {
"id": "C0025506",
"name": "mestranol",
"pos": [
72,
81
]
} |
the influence of progesterone on the conversion of 17-hydroxyprogesterone to testosterone in the mouse testis . | NA | {
"id": "C0033308",
"name": "progesterone",
"pos": [
17,
29
]
} | {
"id": "C0020387",
"name": "17-hydroxyprogesterone",
"pos": [
51,
73
]
} |
the patients , six of whom died , derived from a general population , in contrast to the large series of patients reported in the literature in which the incidence was from 0.9 percent to 3.7 percent . ( 3-6 ) the initial symptoms-rapid respiration , periodic breathing , lethargy and irritability-were identical to thos... | NA | {
"id": "C0231835",
"name": "rapid respiration",
"pos": [
231,
248
]
} | {
"id": "C0035204",
"name": "respiratory disease",
"pos": [
365,
384
]
} |
the evidence for this being the sole system for homoserine transport is ( i ) a linear double-reciprocal plot showing a homoserine k ( m ) of 9.6 x 10 ( -6 ) m , ( ii ) simultaneous reduction by 85 % of homoserine and branched-chain amino acid uptake in a mutant selected for its inability to transport homoserine , and ... | NA | {
"id": "C0002521",
"name": "branched-chain",
"pos": [
218,
232
]
} | {
"id": "C0023401",
"name": "leucine",
"pos": [
451,
458
]
} |
the evidence for this second system consists of ( i ) incomplete inhibition of threonine uptake by any single amino acid , ( ii ) only 70 % loss of threonine uptake in the mutant unable to transport homoserine , and ( iii ) only 40 % reduction of threonine uptake when cells are grown in millimolar leucine . | NA | {
"id": "C0002520",
"name": "amino acid",
"pos": [
110,
120
]
} | {
"id": "C0019892",
"name": "homoserine",
"pos": [
199,
209
]
} |
both enzymes were inhibited to varying degrees by a variety of purine nucleotides besides amp , gmp , and 3':5 ' cyclic amp . | NA | {
"id": "C0034137",
"name": "purine nucleotides",
"pos": [
63,
81
]
} | {
"id": "C0001413",
"name": "amp",
"pos": [
120,
123
]
} |
pseudomonas putida ncib 10015 metabolizes phenol and the cresols ( methylphenols ) by the meta pathway and metabolizes benzoate by the ortho pathway . | NA | {
"id": "C0031428",
"name": "phenol",
"pos": [
42,
48
]
} | {
"id": "C0010305",
"name": "cresols",
"pos": [
57,
64
]
} |
the preferred explanation for these disproportional enzyme levels is that only a fraction of the full complement of ribosomes need initiate translation at lacz for the functional synthesis of lac mrna to occur and that once the lac ribonucleic acid is made a full complement of ribosomes can bind at internal translation... | NA | {
"id": "C0035696",
"name": "mrna",
"pos": [
196,
200
]
} | {
"id": "C0035668",
"name": "ribonucleic acid",
"pos": [
232,
248
]
} |
if a mutant culture was starved for unsaturated fatty acids and harvested just before the lysis started , the fatty acid composition of the cells was the same as that of cells grown until late log phase in a high-osmotic medium . | NA | {
"id": "C0015690",
"name": "unsaturated fatty acids",
"pos": [
36,
59
]
} | {
"id": "C0015684",
"name": "fatty acid",
"pos": [
110,
120
]
} |
assay of l ( plus ) -ascorbic acid in buttermilk by densitometric transmittance measurement of the dehydroascorbic acid osazone . | NA | {
"id": "C0003968",
"name": "ascorbic acid",
"pos": [
21,
34
]
} | {
"id": "C0011177",
"name": "dehydroascorbic acid",
"pos": [
99,
119
]
} |
although the usual diet may contain 150-250 mg of plant sterols , chiefly beta-sitosterol , only trace amounts of these sterols have heretofore been found in human or animal blood and tissues . | NA | {
"id": "C0031866",
"name": "plant sterols",
"pos": [
50,
63
]
} | {
"id": "C0038323",
"name": "sterols",
"pos": [
120,
127
]
} |
the plant sterol content of the red blood cells averaged 12-13 mg/100 ml packed cells or about 13 % of the total sterols . | NA | {
"id": "C0031866",
"name": "plant sterol",
"pos": [
4,
16
]
} | {
"id": "C0038323",
"name": "sterols",
"pos": [
113,
120
]
} |
associated with increased [ eta ] was a decline in albumin : globulin ratio and elevation of the acute phase reactant proteins , alpha ( 1 ) -acid glycoprotein , alpha ( 1 ) -antitrypsin , haptoglobin , and ceruloplasmin . | NA | {
"id": "C0001924",
"name": "albumin",
"pos": [
51,
58
]
} | {
"id": "C0033684",
"name": "proteins",
"pos": [
118,
126
]
} |
associated with increased [ eta ] was a decline in albumin : globulin ratio and elevation of the acute phase reactant proteins , alpha ( 1 ) -acid glycoprotein , alpha ( 1 ) -antitrypsin , haptoglobin , and ceruloplasmin . | NA | {
"id": "C0017649",
"name": "globulin",
"pos": [
61,
69
]
} | {
"id": "C0033684",
"name": "proteins",
"pos": [
118,
126
]
} |
associated with increased [ eta ] was a decline in albumin : globulin ratio and elevation of the acute phase reactant proteins , alpha ( 1 ) -acid glycoprotein , alpha ( 1 ) -antitrypsin , haptoglobin , and ceruloplasmin . | NA | {
"id": "C0001347",
"name": "acute phase reactant",
"pos": [
97,
117
]
} | {
"id": "C0029297",
"name": "alpha ( 1",
"pos": [
129,
138
]
} |
associated with increased [ eta ] was a decline in albumin : globulin ratio and elevation of the acute phase reactant proteins , alpha ( 1 ) -acid glycoprotein , alpha ( 1 ) -antitrypsin , haptoglobin , and ceruloplasmin . | NA | {
"id": "C0001347",
"name": "acute phase reactant",
"pos": [
97,
117
]
} | {
"id": "C0002191",
"name": "alpha ( 1",
"pos": [
129,
138
]
} |
associated with increased [ eta ] was a decline in albumin : globulin ratio and elevation of the acute phase reactant proteins , alpha ( 1 ) -acid glycoprotein , alpha ( 1 ) -antitrypsin , haptoglobin , and ceruloplasmin . | NA | {
"id": "C0001347",
"name": "acute phase reactant",
"pos": [
97,
117
]
} | {
"id": "C0018595",
"name": "haptoglobin",
"pos": [
189,
200
]
} |
associated with increased [ eta ] was a decline in albumin : globulin ratio and elevation of the acute phase reactant proteins , alpha ( 1 ) -acid glycoprotein , alpha ( 1 ) -antitrypsin , haptoglobin , and ceruloplasmin . | NA | {
"id": "C0001347",
"name": "acute phase reactant",
"pos": [
97,
117
]
} | {
"id": "C0007841",
"name": "ceruloplasmin",
"pos": [
207,
220
]
} |
no transpeptidase activity was observed with either gamma-glutamyl p-nitroanilide or oxidized glutathione in contrast to the rabbit-kidney enzyme for which these compounds and glutathione serve as substrates . | NA | {
"id": "C0061516",
"name": "oxidized glutathione",
"pos": [
85,
105
]
} | {
"id": "C0017817",
"name": "glutathione",
"pos": [
176,
187
]
} |
the observed rate of 5-oxoproline formation is consistent with the conclusion that the gamma-glutamyltranspeptidase-cyclotransferase pathway , together with the synthesis of glutathione from glycine , cysteine , and glutamate , account for a large fraction of the observed amino-acid turnover of erythrocyte glutathione ... | NA | {
"id": "C0017890",
"name": "glycine",
"pos": [
191,
198
]
} | {
"id": "C0002520",
"name": "amino-acid",
"pos": [
273,
283
]
} |
the new prostaglandins were 50-200 times ( prostaglandin g ( 2 ) ) and 100-450 times ( prostaglandin h ( 2 ) ) more active than prostaglandin e ( 2 ) on the superfused aorta strip . | NA | {
"id": "C0033554",
"name": "prostaglandin",
"pos": [
8,
21
]
} | {
"id": "C0033559",
"name": "prostaglandin e",
"pos": [
128,
143
]
} |
peptide mapping of aminoacyl-trna synthetases : evidence for internal sequence homology in escherichia coli leucyl-trna synthetase . | NA | {
"id": "C0002529",
"name": "aminoacyl-trna synthetases",
"pos": [
19,
45
]
} | {
"id": "C0023414",
"name": "leucyl-trna synthetase",
"pos": [
108,
130
]
} |
thus , in wild-type cells , phage-induced radioresistance requires some interaction between the bacterial recb gene product ( exonuclease v ) and the phage lambda-protein . | NA | {
"id": "C0004627",
"name": "bacterial",
"pos": [
96,
105
]
} | {
"id": "C0033684",
"name": "protein",
"pos": [
163,
170
]
} |
upon reduction and alkylation , with subsequent separation of peptides by gel filtration , three components were obtained : the largest component ( molecular weight 13,400 ) corresponded to the n-terminal segment of j chain and contained a homoserine residue , the second corresponded to the c-terminal part of j chain w... | NA | {
"id": "C0019892",
"name": "homoserine",
"pos": [
240,
250
]
} | {
"id": "C0002520",
"name": "amino acid",
"pos": [
330,
340
]
} |
these results implicate dopaminergic or classical alpha-adrenergic receptors ( or both ) in inhibition of msh release by catecholamines , and implicate beta-adrenergic receptors in stimulation of msh release by the bioamines . | NA | {
"id": "C0026667",
"name": "msh",
"pos": [
106,
109
]
} | {
"id": "C0005261",
"name": "beta",
"pos": [
152,
156
]
} |
at equal concentrations the order of increasing inhibition of phagocytosis ( assayed at 10 min ) by the prostaglandins was pge ( 1 ) < pgf ( 2alpha ) < pge ( 2 ) < pga ( 1 ) = pga ( 2 ) . | NA | {
"id": "C0033554",
"name": "prostaglandins",
"pos": [
104,
118
]
} | {
"id": "C0033559",
"name": "pge",
"pos": [
152,
155
]
} |
[ solubility of l-amino acids and glycine oligomers in light and heavy water . relation to the thermostability of proteins ] . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
18,
29
]
} | {
"id": "C0017890",
"name": "glycine",
"pos": [
34,
41
]
} |
[ comparative study of the functions of metal phosphate polymers and condense polyphosphates in penicillium chrysogenum ] . | NA | {
"id": "C0031603",
"name": "phosphate",
"pos": [
46,
55
]
} | {
"id": "C0032575",
"name": "polyphosphates",
"pos": [
78,
92
]
} |
the activites of lactic dehydrogenase ( ldh ) , glutamicoxalactic transaminase ( got ) and glutamic-pyruvic transaminase ( gpt ) are investigated within variable periods following tenotomy of m. gastrocnemius in the rat . | NA | {
"id": "C0002594",
"name": "transaminase",
"pos": [
66,
78
]
} | {
"id": "C0001899",
"name": "glutamic-pyruvic transaminase",
"pos": [
91,
120
]
} |
[ study of the structure and technological properties of steels and alloys for the preparation of medical cutting instruments with a narrow cutting edge ] . | NA | {
"id": "C0038239",
"name": "steels",
"pos": [
57,
63
]
} | {
"id": "C0002154",
"name": "alloys",
"pos": [
68,
74
]
} |
[ an experimental study on the effects of corticosteroid hormone to the damaged pulp tissues ( author 's transl ) ] . | NA | {
"id": "C0001617",
"name": "corticosteroid",
"pos": [
42,
56
]
} | {
"id": "C0019932",
"name": "hormone",
"pos": [
57,
64
]
} |
phospholipase was isolated ( in two fractions ) from vipera palestinae venom and it was shown to possess phospholipase a activity ( hydrolyzing diacyl-sn-glycerophosphorylcholines , e.g. , lecithin , in the 2-position ) as well as lysophospholipase ( phospholipase b ) activity ( hydrolyzing 1-monoacyl-sn-glycerophospho... | NA | {
"id": "C0031671",
"name": "phospholipase",
"pos": [
0,
13
]
} | {
"id": "C0024361",
"name": "phospholipase b",
"pos": [
251,
266
]
} |
phospholipase was isolated ( in two fractions ) from vipera palestinae venom and it was shown to possess phospholipase a activity ( hydrolyzing diacyl-sn-glycerophosphorylcholines , e.g. , lecithin , in the 2-position ) as well as lysophospholipase ( phospholipase b ) activity ( hydrolyzing 1-monoacyl-sn-glycerophospho... | NA | {
"id": "C0031617",
"name": "lecithin",
"pos": [
189,
197
]
} | {
"id": "C0017889",
"name": "glycerophosphorylcholine",
"pos": [
385,
409
]
} |
it was demonstrated that testicular microsomes can desaturate and elongate linoleic and arachidonic acids in a manner similar to liver microsomes , and that testicular mitochondria can convert docosa-7,10,13,16-tetraenoic acid to arachidonic acid . | NA | {
"id": "C0003701",
"name": "arachidonic acids",
"pos": [
88,
105
]
} | {
"id": "C0003695",
"name": "acid",
"pos": [
242,
246
]
} |
the hydrocarbons were the c ( 14 ) to c ( 27 ) and the c ( 29 ) to c ( 31 ) straight-chain paraffins , their monoolefin analogs , and the c ( 25 ) to c ( 29 ) branched alkanes . | NA | {
"id": "C0020242",
"name": "hydrocarbons",
"pos": [
4,
16
]
} | {
"id": "C0030415",
"name": "paraffins",
"pos": [
91,
100
]
} |
an inhibition of amino acid incorporation into hepatic lipoprotein apoprotein was observed , with an associated decrease in circulating vldl apoprotein , decreased serum triglyceride concentration , and a loss of the pre-beta band as judged by serum lipoprotein electrophoresis . | NA | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
55,
66
]
} | {
"id": "C0023825",
"name": "vldl",
"pos": [
136,
140
]
} |
the ph and hammett acidity dependences of the absorption and fluorescence spectra of cinchoninic acid ( quinoline-4-carboxylic acid ) , cinchophen ( 2-phenylquinoline-4-carboxylic acid ) and their methyl esters , were studied . | NA | {
"id": "C0007066",
"name": "carboxylic acid",
"pos": [
116,
131
]
} | {
"id": "C0014898",
"name": "esters",
"pos": [
204,
210
]
} |
with hydrogen peroxide as oxidizing agent and a trace of fe ( ii ) there is considerable decomposition of peroxide , under a nitrogen atmosphere , after a few hours at 25 degrees in light ( from a tungsten lamp ) , and less decomposition in the dark . | NA | {
"id": "C0020281",
"name": "hydrogen peroxide",
"pos": [
5,
22
]
} | {
"id": "C0031180",
"name": "peroxide",
"pos": [
106,
114
]
} |
after attack with acids these two elements are separated from each other and from matrix elements by means of anion-exchange in 6m hydrochloric acid on the strongly basic anion-exchange resin dowex 1 , x8 ( chloride form ) . | NA | {
"id": "C0003075",
"name": "anion",
"pos": [
110,
115
]
} | {
"id": "C0008203",
"name": "chloride",
"pos": [
207,
215
]
} |
the technique of thin-layer chromatography , as practised in the organic industrial laboratory , is described and its applications to the analysis of petroleum hydrocarbons , fuels , lubricants , polymers , plastics and their additives , non-ionic surfactants and explosives are reviewed . | NA | {
"id": "C0032521",
"name": "polymers",
"pos": [
196,
204
]
} | {
"id": "C0032167",
"name": "plastics",
"pos": [
207,
215
]
} |
the interference by excess of peroxide seriously affects the reliability of chromium determination procedures involving prior oxidation of the element with sodium or hydrogen peroxide . | NA | {
"id": "C0031180",
"name": "peroxide",
"pos": [
30,
38
]
} | {
"id": "C0020281",
"name": "hydrogen peroxide",
"pos": [
166,
183
]
} |
the distribution coefficients have been determined for rb ( + ) distributed between zirconium phosphate and 0.85m hydrochloric acid in aqueous solutions of methanol , ethanol , n-propanol , isopropyl alcohol , t-butyl alcohol , dimethylsulphoxide , dimethylformamide , tetrahydrofuran , acetone , dioxane , `` '' methylc... | NA | {
"id": "C0001962",
"name": "ethanol",
"pos": [
157,
164
]
} | {
"id": "C0022237",
"name": "isopropyl alcohol",
"pos": [
190,
207
]
} |
a gas chromatographic method is reported for the separation and subsequent quantitative determination of the cerium group lanthanides . | NA | {
"id": "C0007828",
"name": "cerium",
"pos": [
109,
115
]
} | {
"id": "C0205838",
"name": "lanthanides",
"pos": [
122,
133
]
} |
polyvinyl acetate and iodine form a characteristic red complex in the presence of potassium iodide . | NA | {
"id": "C0021966",
"name": "iodine",
"pos": [
22,
28
]
} | {
"id": "C0032831",
"name": "potassium iodide",
"pos": [
82,
98
]
} |
the frozen water is then vaporized by heating in a hydrogen flow of 30 ml/min and reduced on magnesium at 600 degrees . deuterium is obtained as deuterium hydride in hydrogen ; | NA | {
"id": "C0011744",
"name": "deuterium",
"pos": [
120,
129
]
} | {
"id": "C0020275",
"name": "hydrogen",
"pos": [
166,
174
]
} |
four triphenylmethane derivatives ( cations ) and a high molecular-weight quaternary ammonium ion were used as the ion-exchange site in the liquid membranes of electrodes responsive to aromatic sulphonate ions , such as benzenesulphonate and alpha-naphthalenesulphonate . | NA | {
"id": "C0007447",
"name": "cations",
"pos": [
36,
43
]
} | {
"id": "C0022023",
"name": "ions",
"pos": [
205,
209
]
} |
desorption of small quantities of chloraurate ions retained on anion-exchangers , in the separation of gold from base metals . | NA | {
"id": "C0022023",
"name": "ions",
"pos": [
46,
50
]
} | {
"id": "C0003075",
"name": "anion",
"pos": [
63,
68
]
} |
they are as follows : lupin component i : ala20 , arg1 , ( asp + asn ) 17 , ( glu + gln ) 17 , gly9 , his4 , ile9 , leu15 , lys17 , met1 , phe8 , pro5 , ser12 , thr9 , trp3 , tyr2 and val17 . | NA | {
"id": "C0061472",
"name": "glu",
"pos": [
78,
81
]
} | {
"id": "C0017797",
"name": "gln",
"pos": [
84,
87
]
} |
lupin component ii : ala26 , arg1 , ( asp + asn ) 18 , ( glu + gln ) 20 , gly9 , his5 , ile10 , leu16 , lys18 , met1 , phe8 , pro6 , ser12 , thr10 , trp3 , tyr2 and val18 . | NA | {
"id": "C0061472",
"name": "glu",
"pos": [
57,
60
]
} | {
"id": "C0017797",
"name": "gln",
"pos": [
63,
66
]
} |
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