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the proportion of predominantly polymicrobial multiple infections was 54.2 % , the remaining 45.8 % of the cases involving mono-microbial infection .
NA
{ "id": "C0275524", "name": "polymicrobial", "pos": [ 32, 45 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 138, 147 ] }
the estimation of s-iga was carried out by means of an antiserum against human secretory component ( anti sc ) and s-iga standard .
NA
{ "id": "C0036538", "name": "secretory component", "pos": [ 79, 98 ] }
{ "id": "C0020838", "name": "s-iga", "pos": [ 115, 120 ] }
the study of immunocomplexes obtained from antisera to the preparations of y. pestis outer membranes and membrane proteins has revealed that outer membrane proteins are involved in the formation of the immunocomplex and belong to previously unknown y. pestis ev antigens .
NA
{ "id": "C0025252", "name": "membrane proteins", "pos": [ 105, 122 ] }
{ "id": "C0033684", "name": "proteins", "pos": [ 156, 164 ] }
the study showed that at the period when liquid poliomyelitis vaccine was used the share immune to polioviruses , types 1 and 2 , constituted 89.4 % and 98.0 % , respectively , as compared with 67.0 % and 68.0 % at the period when sugar-coated live dried poliomyelitis vaccine was administered .
NA
{ "id": "C0032374", "name": "poliomyelitis vaccine", "pos": [ 48, 69 ] }
{ "id": "C0770698", "name": "live", "pos": [ 244, 248 ] }
the course of the disease was chronic except for one patient who had a spontaneous remission after 5 years .
NA
{ "id": "C0242656", "name": "course of", "pos": [ 4, 13 ] }
{ "id": "C0035053", "name": "spontaneous remission", "pos": [ 71, 92 ] }
the effect of other anticonvulsants ( phenytoin , phenobarbitone and primidone ) on serum clonazepam concentrations has been studied .
NA
{ "id": "C0031412", "name": "phenobarbitone", "pos": [ 50, 64 ] }
{ "id": "C0033148", "name": "primidone", "pos": [ 69, 78 ] }
from the electron probe microanalysis of lewy bodies and adrenal bodies , we find that the lewy body contains sulfur , calcium , and phosphorus , and the adrenal body also contains these three elements .
NA
{ "id": "C0031705", "name": "phosphorus", "pos": [ 133, 143 ] }
{ "id": "C0013879", "name": "elements", "pos": [ 193, 201 ] }
in grades of kyphosis and lordosis no difference was observed between the groups with spinal curvature and without .
NA
{ "id": "C0022821", "name": "kyphosis", "pos": [ 13, 21 ] }
{ "id": "C0037932", "name": "spinal curvature", "pos": [ 86, 102 ] }
in grades of kyphosis and lordosis no difference was observed between the groups with spinal curvature and without .
NA
{ "id": "C0024003", "name": "lordosis", "pos": [ 26, 34 ] }
{ "id": "C0037932", "name": "spinal curvature", "pos": [ 86, 102 ] }
four women aged 87 , 77 , 74 and 69 years with severely comminuted , displaced and intraarticular colles ' fractures of the dominant hand , where conservative treatment had failed , were treated by use of intramedullary methylmethacrylate stabilisation in order to retain optimal anatomical position of the fracture .
NA
{ "id": "C0476171", "name": "comminuted", "pos": [ 56, 66 ] }
{ "id": "C0016658", "name": "fracture", "pos": [ 307, 315 ] }
sympathomimetic agents ( noradrenaline , adrenaline , oxymetazoline , phenylephrine ) , 5-hydroxytryptamine , histamine , angiotensin ii , and prostaglandin f2 alpha all induced concentration-dependent contractile responses .
NA
{ "id": "C0028351", "name": "noradrenaline", "pos": [ 25, 38 ] }
{ "id": "C0014563", "name": "adrenaline", "pos": [ 41, 51 ] }
inhibition by low molecular weight dextran of the blood pressure fall and the lowering of plasminogen proactivator induced by clinical dextran in the rat .
NA
{ "id": "C0011793", "name": "low molecular weight dextran", "pos": [ 14, 42 ] }
{ "id": "C0086140", "name": "dextran", "pos": [ 135, 142 ] }
all three d2 receptor antagonists precipitated signs of acute dystonia at some dose levels , but out of the test drugs only metoclopramide caused deterioration of dyskinetic symptoms .
NA
{ "id": "C2917388", "name": "d2 receptor antagonists", "pos": [ 10, 33 ] }
{ "id": "C0025853", "name": "metoclopramide", "pos": [ 124, 138 ] }
the relative affinity of some adrenoceptor agonists was : ( - ) -adrenaline greater than ( - ) -noradrenaline much greater than ( +/- ) -isoprenaline .
NA
{ "id": "C0014563", "name": "adrenaline", "pos": [ 65, 75 ] }
{ "id": "C0028351", "name": "noradrenaline", "pos": [ 96, 109 ] }
cells cultured from the rabbit hnk cortex contain fibroblast-like cells and phagocytic cells which respond to bk with a profound pg production .
NA
{ "id": "C0007634", "name": "cells", "pos": [ 0, 5 ] }
{ "id": "C0016030", "name": "fibroblast", "pos": [ 50, 60 ] }
no significant difference in arrhythmia frequency was found between elderly subjects with heart disease and those without heart disease or between elderly subjects without symptoms and those with non-episodic symptoms such as dizziness .
NA
{ "id": "C0003811", "name": "arrhythmia", "pos": [ 29, 39 ] }
{ "id": "C0018799", "name": "heart disease", "pos": [ 122, 135 ] }
immune complexes formed from salmonella minnesota re glycolipid ( gl ) and its derivative dmso-gl with homologous antibodies exhibited stronger interferon ( ifn ) -inducing activity than the free gl ( 4- to 32-fold increase and 8- to 64-fold increase respectively ) .
NA
{ "id": "C0003313", "name": "immune complexes", "pos": [ 0, 16 ] }
{ "id": "C0003241", "name": "antibodies", "pos": [ 114, 124 ] }
21 women with igm antibodies to cytomegalovirus-induced late antigen ( cmv la ) as determined in the first , second or third trimester were tested for the persistence of these antibodies during pregnancy and postpartum .
NA
{ "id": "C0032981", "name": "third trimester", "pos": [ 119, 134 ] }
{ "id": "C0032961", "name": "pregnancy", "pos": [ 194, 203 ] }
by means of a radioenzymatic assay , we measured plasma norepinephrine ( ne ) and epinephrine ( e ) concentrations in nine normal , sedentary men , aged 22 to 34 years .
NA
{ "id": "C0028351", "name": "norepinephrine", "pos": [ 56, 70 ] }
{ "id": "C0014563", "name": "epinephrine", "pos": [ 82, 93 ] }
of the 9 patients with multiple vt morphologies , the vt originated at disparate sites in 2 patients .
NA
{ "id": "C0039231", "name": "vt", "pos": [ 32, 34 ] }
{ "id": "C0042514", "name": "vt", "pos": [ 54, 56 ] }
thus , for tachycardias terminating with single captures , the first train to achieve capture was effective , minimizing the duration of the vt .
NA
{ "id": "C0039231", "name": "tachycardias", "pos": [ 11, 23 ] }
{ "id": "C0042514", "name": "vt", "pos": [ 141, 143 ] }
intimal changes and medial thickness of small pulmonary arteries were morphometrically examined in 21 cases of simple cardiac anomalies with the down syndrome , and their correlations with age and with pulmonary arterial peak pressure were then compared with those of 20 cases of simple cardiac anomalies without the dow...
NA
{ "id": "C0018798", "name": "cardiac anomalies", "pos": [ 118, 135 ] }
{ "id": "C0040761", "name": "of", "pos": [ 370, 372 ] }
the close resemblance of these cells to endoneurial fibroblasts of peripheral nerve and to hyalocytes of the vitreous body is emphasized .
NA
{ "id": "C0007634", "name": "the", "pos": [ 0, 3 ] }
{ "id": "C0016030", "name": "fibroblasts", "pos": [ 52, 63 ] }
the quality of dietary fat had a clear influence on serum fatty acids , eg , the content of 18:2 in ce was 56.8 +/- 3.6 % in boys using soft vegetable margarine and 50.5 +/- 3.6 % in those using butter .
NA
{ "id": "C0012171", "name": "dietary fat", "pos": [ 15, 26 ] }
{ "id": "C0024798", "name": "margarine", "pos": [ 151, 160 ] }
the quality of dietary fat had a clear influence on serum fatty acids , eg , the content of 18:2 in ce was 56.8 +/- 3.6 % in boys using soft vegetable margarine and 50.5 +/- 3.6 % in those using butter .
NA
{ "id": "C0012171", "name": "dietary fat", "pos": [ 15, 26 ] }
{ "id": "C0006494", "name": "butter", "pos": [ 195, 201 ] }
using the clinical history and standard laboratory tests ( hematocrit , per cent saturation of transferrin ( % sat ) , serum ferritin , hb electrophoresis , hba2 , and hbf ) we classified 198 adults with microcytic rbc as follows : 48 ida , 11 probable ida , 11 iron-deficient erythropoiesis without anemia , 13 acd , 42...
NA
{ "id": "C0019046", "name": "hb", "pos": [ 136, 138 ] }
{ "id": "C0015936", "name": "hbf", "pos": [ 168, 171 ] }
we report the case of a woman who presented with a typical picture of cholelithiasis and choledocholithiasis .
NA
{ "id": "C0008350", "name": "cholelithiasis", "pos": [ 70, 84 ] }
{ "id": "C0701818", "name": "choledocholithiasis", "pos": [ 89, 108 ] }
a case of juvenile hepatocellular carcinoma associated with liver cirrhosis in a family clustering of hbs antigen carriers and liver diseases .
NA
{ "id": "C0023890", "name": "liver cirrhosis", "pos": [ 60, 75 ] }
{ "id": "C0023895", "name": "liver diseases", "pos": [ 127, 141 ] }
we provide information about the interaction of protamine sulfate with purified , labeled thrombin and atiii through binding experiments in which protamine is shown to inhibit the inactivation of thrombin by atiii .
NA
{ "id": "C0033602", "name": "protamine sulfate", "pos": [ 48, 65 ] }
{ "id": "C0033603", "name": "protamine", "pos": [ 146, 155 ] }
a subgroup of 43 men was further screened for both humoral anti-lung antibodies ( ala ) and direct lymphocyte-mediated cellular cytotoxicity ( lmcc ) towards human embryonic lung fibroblasts ( hel ) .
NA
{ "id": "C0007634", "name": "cellular", "pos": [ 119, 127 ] }
{ "id": "C0016030", "name": "fibroblasts", "pos": [ 179, 190 ] }
elevated levels of plasma low-density lipoprotein and/or very low-density lipoprotein cholesterol , as seen in hypercholesterolemia and/or hypertriglyceridemia , are primarily caused by a diet high in saturated fat , cholesterol , and calories , and by excessive intake of alcohol .
NA
{ "id": "C0023826", "name": "very low-density", "pos": [ 57, 73 ] }
{ "id": "C0008377", "name": "cholesterol", "pos": [ 217, 228 ] }
drug therapy should be instituted only after appropriate diet treatment has been started and adequate baseline lipid and lipoprotein values are established .
NA
{ "id": "C0023779", "name": "lipid", "pos": [ 111, 116 ] }
{ "id": "C0023820", "name": "lipoprotein", "pos": [ 121, 132 ] }
three other x-linked conditions were identified : in one family , the coffin-lowry syndrome , in another , duchenne muscular dystrophy , and in two families x-linked mr and muscle atrophy .
NA
{ "id": "C0265252", "name": "coffin-lowry", "pos": [ 70, 82 ] }
{ "id": "C1136249", "name": "x-linked", "pos": [ 157, 165 ] }
the effects of parenterally administered magnesium sulfate on maternal and neonatal calcium and magnesium metabolism in nonasphyxiated , term pregnancies complicated by pregnancy-induced hypertension were studied prospectively .
NA
{ "id": "C0024480", "name": "magnesium sulfate", "pos": [ 41, 58 ] }
{ "id": "C0024467", "name": "magnesium", "pos": [ 96, 105 ] }
dietary restriction caused a net maternal weight loss and a 20 % reduction in mean fetal weight and mean placental weight by day 21 of gestation .
NA
{ "id": "C0751992", "name": "fetal weight", "pos": [ 83, 95 ] }
{ "id": "C0005910", "name": "weight", "pos": [ 115, 121 ] }
restricted dams fed ad libitum during the last week of gestation showed a net maternal weight gain , while mean fetal weight , but not placental weight , was near that of the ad libitum -- fed controls .
NA
{ "id": "C0751992", "name": "fetal weight", "pos": [ 112, 124 ] }
{ "id": "C0005910", "name": "weight", "pos": [ 145, 151 ] }
the stability of human chorionic gonadotropin ( hcg ) and its alpha-subunit in whole blood , plasma , and serum under a variety of sample handling conditions commonly encountered in clinics , hospital wards , physician 's offices , and clinical service laboratories was investigated with the use of radioreceptor assay ,...
NA
{ "id": "C0018062", "name": "human chorionic gonadotropin", "pos": [ 17, 45 ] }
{ "id": "C0017963", "name": "alpha-subunit", "pos": [ 62, 75 ] }
the results clearly demonstrate that hcg and its alpha-subunit are stable in unfrozen whole blood , plasma , and serum for at least 6 days and in frozen plasma and serum samples for at least 6 months .
NA
{ "id": "C0018062", "name": "hcg", "pos": [ 37, 40 ] }
{ "id": "C0017963", "name": "alpha-subunit", "pos": [ 49, 62 ] }
hemolysis in samples resulted in a 20 % to 30 % decrease in hcg and its alpha-subunit levels , which may be attributable to sample dilution .
NA
{ "id": "C0018062", "name": "hcg", "pos": [ 60, 63 ] }
{ "id": "C0017963", "name": "alpha-subunit", "pos": [ 72, 85 ] }
complications such as bleeding in the first and third trimesters , abnormal presentations and premature rupture of the membranes , abruptio placentae , fetal distress , low birth weight , short gestation , and major malformations occurred more often among women with a history of two or more induced abortions .
NA
{ "id": "C0032981", "name": "third", "pos": [ 48, 53 ] }
{ "id": "C0032961", "name": "gestation", "pos": [ 194, 203 ] }
a total of 204 infertile women attending the infertility clinic of the medical center hospital of vermont were studied for the possible role of chlamydia trachomatis and intrauterine contraceptive device ( iucd ) use as factors related to their infertility .
NA
{ "id": "C0021361", "name": "infertile women", "pos": [ 15, 30 ] }
{ "id": "C0021359", "name": "infertility", "pos": [ 245, 256 ] }
electrophoretic mobility of ck activity on cellulose acetate further indicates that the endometrial enzyme is a bb ( brain type ) isoenzyme .
NA
{ "id": "C0014442", "name": "enzyme", "pos": [ 100, 106 ] }
{ "id": "C0022173", "name": "isoenzyme", "pos": [ 130, 139 ] }
the maximum maternal venous blood ethanol concentration was twice the maximum amniotic fluid ethanol concentration and occurred at an earlier time .
NA
{ "id": "C0684262", "name": "blood ethanol", "pos": [ 28, 41 ] }
{ "id": "C0001962", "name": "ethanol", "pos": [ 93, 100 ] }
it is proposed that the amniotic fluid may act as a reservoir for ethanol following maternal ingestion such that the fetus would be exposed to ethanol for a longer time period than would be predicted by the maternal venous blood ethanol concentration .
NA
{ "id": "C0001962", "name": "ethanol", "pos": [ 66, 73 ] }
{ "id": "C0684262", "name": "blood ethanol concentration", "pos": [ 223, 250 ] }
fourteen days later , each eye was injected with homologous fibroblasts ( ten eyes with 100,000 cells , 25 eyes with 250,000 cells , and ten eyes with 750,000 cells ) .
NA
{ "id": "C0016030", "name": "fibroblasts", "pos": [ 60, 71 ] }
{ "id": "C0007634", "name": "cells", "pos": [ 159, 164 ] }
sodium hyaluronate ( healon ) is an ideal material for protecting the cornea during intraocular lens implantation and protecting donor corneal material during corneal transplantation .
NA
{ "id": "C0087000", "name": "sodium hyaluronate", "pos": [ 0, 18 ] }
{ "id": "C0020196", "name": "healon", "pos": [ 21, 27 ] }
colloidial carbon was employed as a vascular label for detection of microvascular endothelial structural alterations , and horseradish peroxidase was used as a tracer probe for localization of cell-membrane permeability dysfunction of allograft endothelium and cardiocytes as well as of elements of the cellular infiltra...
NA
{ "id": "C0007009", "name": "carbon", "pos": [ 11, 17 ] }
{ "id": "C0013879", "name": "elements", "pos": [ 287, 295 ] }
potassium movements through the latter channel were stimulated when chloride was replaced by more permeant anions , such as nitrate and thiocyanate , which also increased the rate of net potassium movements in valinomycin-treated cells .
NA
{ "id": "C0008203", "name": "chloride", "pos": [ 68, 76 ] }
{ "id": "C0003075", "name": "anions", "pos": [ 107, 113 ] }
potassium movements through the latter channel were stimulated when chloride was replaced by more permeant anions , such as nitrate and thiocyanate , which also increased the rate of net potassium movements in valinomycin-treated cells .
NA
{ "id": "C0003075", "name": "anions", "pos": [ 107, 113 ] }
{ "id": "C0028125", "name": "nitrate", "pos": [ 124, 131 ] }
the possibility is considered that the rates of sodium-dependent calcium transport in the presence of chloride , nitrate , and thiocyanate are a function of the conductance of these anions .
NA
{ "id": "C0008203", "name": "chloride", "pos": [ 102, 110 ] }
{ "id": "C0003075", "name": "anions", "pos": [ 182, 188 ] }
the possibility is considered that the rates of sodium-dependent calcium transport in the presence of chloride , nitrate , and thiocyanate are a function of the conductance of these anions .
NA
{ "id": "C0028125", "name": "nitrate", "pos": [ 113, 120 ] }
{ "id": "C0003075", "name": "anions", "pos": [ 182, 188 ] }
retardation of sodium movements in shrunken cells occurs when chloride is replaced by the more conductive anions : nitrate or thiocyanate .
NA
{ "id": "C0008203", "name": "chloride", "pos": [ 62, 70 ] }
{ "id": "C0003075", "name": "anions", "pos": [ 106, 112 ] }
retardation of sodium movements in shrunken cells occurs when chloride is replaced by the more conductive anions : nitrate or thiocyanate .
NA
{ "id": "C0003075", "name": "anions", "pos": [ 106, 112 ] }
{ "id": "C0028125", "name": "nitrate", "pos": [ 115, 122 ] }
the relative potencies and efficacies of l-isoproterenol , l-epinephrine , l-norepinephrine , terbutaline , and dobutamine for physiological and biochemical events were similar .
NA
{ "id": "C0014563", "name": "epinephrine", "pos": [ 61, 72 ] }
{ "id": "C0028351", "name": "l-norepinephrine", "pos": [ 75, 91 ] }
unlabeled proinsulin also displaced [ 125i ] iodoinsulin in a dose-dependent manner , being 1 % as potent as insulin .
NA
{ "id": "C0033362", "name": "proinsulin", "pos": [ 10, 20 ] }
{ "id": "C0021641", "name": "insulin", "pos": [ 109, 116 ] }
whereas the majority of gluconeogenic amino acids decreased in concentration in the maternal circulation during fasting , the branched-chain amino acids , as well as 3-methylhistidine , increased .
NA
{ "id": "C0002520", "name": "amino acids", "pos": [ 38, 49 ] }
{ "id": "C0002521", "name": "branched-chain amino acids", "pos": [ 126, 152 ] }
from these findings we conclude that sequestering of estradiol by the rabbit corpus luteum in vivo is accomplished by the steroid-specific estrogen receptor that shares characteristics of the estrogen receptor found in human breast cancers , including a ) antigenic features and b ) the capacity to translocate estrogens...
NA
{ "id": "C0034840", "name": "steroid", "pos": [ 122, 129 ] }
{ "id": "C0034804", "name": "estrogen receptor", "pos": [ 192, 209 ] }
reabsorption of nacl from the high-chloride , low-bicarbonate fluid in the late proximal tubule is approximately 40 % passive and 60 % active .
NA
{ "id": "C0037494", "name": "nacl", "pos": [ 16, 20 ] }
{ "id": "C0008203", "name": "chloride", "pos": [ 35, 43 ] }
the mechanisms for neutral nacl transport across the luminal membrane and for chloride exit across the basolateral membrane are unknown .
NA
{ "id": "C0037494", "name": "nacl", "pos": [ 27, 31 ] }
{ "id": "C0008203", "name": "chloride", "pos": [ 78, 86 ] }
the competitive inhibition studies show that the apparent kd values for ( - ) -isoproterenol , ( - ) -epinephrine , and ( - ) -norepinephrine were increased by 14 , 51 , and 5 times , respectively , 2 h postendotoxin .
NA
{ "id": "C0014563", "name": "epinephrine", "pos": [ 102, 113 ] }
{ "id": "C0028351", "name": "norepinephrine", "pos": [ 127, 141 ] }
these findings suggest that neuroendocrine abnormalities identified previously in anorexia nervosa are not solely an artifact of low weight and , further , that eating disorders and affective disorders may share neurochemical similarities .
NA
{ "id": "C0003125", "name": "anorexia nervosa", "pos": [ 82, 98 ] }
{ "id": "C0013473", "name": "eating disorders", "pos": [ 161, 177 ] }
twenty-four individuals demonstrated substantial behavioral abnormalities , including affective and schizophrenic syndromes , changes of personality , and disorders that could not be classified adequately .
NA
{ "id": "C0039082", "name": "syndromes", "pos": [ 114, 123 ] }
{ "id": "C0012634", "name": "disorders", "pos": [ 155, 164 ] }
the authors review theoretical and clinical data supporting the hypothesis that l-tryptophan may potentiate the effects of lithium carbonate and report on a double-blind clinical comparison of lithium plus l-tryptophan and lithium plus placebo in 9 bipolar and 7 schizoaffective patients .
NA
{ "id": "C0085217", "name": "lithium carbonate", "pos": [ 123, 140 ] }
{ "id": "C0023870", "name": "lithium", "pos": [ 223, 230 ] }
plasma amino acid abnormalities are frequently reported in alcoholics , with the most common abnormalities being those of depressed branched chain amino acids ( bcaa ) and increased aromatic amino acids .
NA
{ "id": "C0002520", "name": "amino acid", "pos": [ 7, 17 ] }
{ "id": "C0002521", "name": "branched chain amino acids", "pos": [ 132, 158 ] }
the high levels of aromatic amino acids such as tyrosine and tryptophan as well as their breakdown products may be due to impaired hepatic metabolism and appear to play a role in the pathogenesis of hepatic encephalopathy .
NA
{ "id": "C0301713", "name": "aromatic amino acids", "pos": [ 19, 39 ] }
{ "id": "C0041485", "name": "tyrosine", "pos": [ 48, 56 ] }
the high levels of aromatic amino acids such as tyrosine and tryptophan as well as their breakdown products may be due to impaired hepatic metabolism and appear to play a role in the pathogenesis of hepatic encephalopathy .
NA
{ "id": "C0301713", "name": "aromatic amino acids", "pos": [ 19, 39 ] }
{ "id": "C0041249", "name": "tryptophan", "pos": [ 61, 71 ] }
characteristically , in most persons with shock reactions unconsciousness and death occurred very shortly after the sting ( within 45 min ) , while the interval between sting and death was longer ( 30 min to a couple of hours ) when death was caused by suffocation .
NA
{ "id": "C0011065", "name": "death", "pos": [ 78, 83 ] }
{ "id": "C0004044", "name": "suffocation", "pos": [ 253, 264 ] }
in 19 patients ( that is 46.3 % ) myopathic aspects were found in form of minimal changes , but also of syndrome-like tissue alterations ( e.g . core disease , muscle dystrophy ) .
NA
{ "id": "C0039082", "name": "syndrome", "pos": [ 104, 112 ] }
{ "id": "C0012634", "name": "disease", "pos": [ 150, 157 ] }
[ effect of thiopental anesthesia on plasma renin , adrenaline and noradrenaline in neurosurgical operations with induced hypotension ] .
NA
{ "id": "C0014563", "name": "adrenaline", "pos": [ 52, 62 ] }
{ "id": "C0028351", "name": "noradrenaline", "pos": [ 67, 80 ] }
plasma renin activity ( pra ) , plasma concentration of adrenaline and noradrenaline were determined in 13 patients , undergoing surgery of cerebral aneurysms with induced hypotension ( group i ) and in 15 patients , who were operated on for brain tumors without hypotension ( group ii ) .
NA
{ "id": "C0014563", "name": "adrenaline", "pos": [ 56, 66 ] }
{ "id": "C0028351", "name": "noradrenaline", "pos": [ 71, 84 ] }
the extent of reduction in the color , due to chelation of cu2+ by the immobilized proteins , indicates the amount of protein .
NA
{ "id": "C2350558", "name": "immobilized proteins", "pos": [ 71, 91 ] }
{ "id": "C0033684", "name": "protein", "pos": [ 118, 125 ] }
a microapparatus for liquid hydrogen fluoride solvolysis : sugar and amino sugar composition of erysiphe graminis and triticum aestivum cell walls .
NA
{ "id": "C0007004", "name": "sugar", "pos": [ 59, 64 ] }
{ "id": "C0002531", "name": "amino sugar", "pos": [ 69, 80 ] }
excess gtp at the end of reaction was controlled by simultaneous detection of guanine nucleotides at 254 nm .
NA
{ "id": "C0018353", "name": "gtp", "pos": [ 7, 10 ] }
{ "id": "C0018328", "name": "guanine nucleotides", "pos": [ 78, 97 ] }
the detection limits for glutathione , coenzyme a , cysteamine , homocysteine , n-acetylcysteine , cysteine , and d-3-mercaptomethylpropanoyl-l-proline ( captopril ) were 100 , 120 , 160 , 330 , 390 , 3600 , and 150 pmol/ml , respectively .
NA
{ "id": "C0001047", "name": "n-acetylcysteine", "pos": [ 80, 96 ] }
{ "id": "C0010654", "name": "cysteine", "pos": [ 99, 107 ] }
the detection limits for glutathione , coenzyme a , cysteamine , homocysteine , n-acetylcysteine , cysteine , and d-3-mercaptomethylpropanoyl-l-proline ( captopril ) were 100 , 120 , 160 , 330 , 390 , 3600 , and 150 pmol/ml , respectively .
NA
{ "id": "C0033382", "name": "proline", "pos": [ 144, 151 ] }
{ "id": "C0006938", "name": "captopril", "pos": [ 154, 163 ] }
the addition of cyanide significantly changed the substance concentration ( fractional content times substance concentration of total cobalamins ) for all the cobalamin forms except 5'-deoxyadenosylcobalamin .
NA
{ "id": "C0086024", "name": "cobalamins", "pos": [ 134, 144 ] }
{ "id": "C0042845", "name": "cobalamin", "pos": [ 198, 207 ] }
( iii ) studies of the cobalamin forms in body fluids and tissue cells need to be repeated by methods ensuring equal extraction of all the cobalamins ;
NA
{ "id": "C0042845", "name": "cobalamin", "pos": [ 23, 32 ] }
{ "id": "C0086024", "name": "cobalamins", "pos": [ 139, 149 ] }
with catalytic debromination in the presence of hydrogen or tritium gas , bromine atoms in the derivatives were completely substituted by hydrogen or tritium .
NA
{ "id": "C0020275", "name": "hydrogen", "pos": [ 48, 56 ] }
{ "id": "C0041119", "name": "tritium", "pos": [ 150, 157 ] }
tritiated phlorizin with extremely high specific radioactivity ( 45 ci/mmol ) was obtained when hydrogen gas was replaced by tritium gas .
NA
{ "id": "C0020275", "name": "hydrogen", "pos": [ 96, 104 ] }
{ "id": "C0041119", "name": "tritium", "pos": [ 125, 132 ] }
further studies indicated that glutaraldehyde enhancement of protein staining with this silver reagent was probably due to oxidation of the aldehyde groups by silver ions , resulting in metallic silver depositions within the gel which act as nucleation sites for additional metallic silver localization in the protein ba...
NA
{ "id": "C0017814", "name": "glutaraldehyde", "pos": [ 31, 45 ] }
{ "id": "C0001992", "name": "aldehyde", "pos": [ 349, 357 ] }
because in a previous study it was shown that exercise while breathing warm humid air could induce a refractory period without itself causing asthma , we conclude that hyperventilation-induced asthma is not the same as exercise-induced asthma in most subjects .
NA
{ "id": "C0004096", "name": "asthma", "pos": [ 142, 148 ] }
{ "id": "C0004099", "name": "exercise-induced asthma", "pos": [ 219, 242 ] }
we found ( 1 ) that in a 3-h incubation after brief exposure to neutrophil elastase , control alveolar macrophages partially degraded bound enzyme , but they also released intact , enzymatically active , elastase in small amounts ;
NA
{ "id": "C0064833", "name": "neutrophil elastase", "pos": [ 64, 83 ] }
{ "id": "C0030306", "name": "elastase", "pos": [ 204, 212 ] }
in the sprague-dawley rat , acute and chronic administration of sodium salts other than sodium chloride failed to suppress plasma renin activity , whereas renin was inhibited by both sodium chloride and by selective chloride ( without sodium ) loading .
NA
{ "id": "C0037494", "name": "sodium chloride", "pos": [ 88, 103 ] }
{ "id": "C0008203", "name": "chloride", "pos": [ 216, 224 ] }
thus , both the renin and possibly the blood pressure responses to sodium chloride are dependent on chloride .
NA
{ "id": "C0037494", "name": "sodium chloride", "pos": [ 67, 82 ] }
{ "id": "C0008203", "name": "chloride", "pos": [ 100, 108 ] }
the toxicological action of several heavy metal ions including cadmium , lead , mercury , and thallium can cause hypertension by affecting hormone metabolism , vasoconstriction , and renal tubular function .
NA
{ "id": "C0347988", "name": "heavy metal", "pos": [ 36, 47 ] }
{ "id": "C0006632", "name": "cadmium", "pos": [ 63, 70 ] }
the toxicological action of several heavy metal ions including cadmium , lead , mercury , and thallium can cause hypertension by affecting hormone metabolism , vasoconstriction , and renal tubular function .
NA
{ "id": "C0347988", "name": "heavy metal", "pos": [ 36, 47 ] }
{ "id": "C0023175", "name": "lead", "pos": [ 73, 77 ] }
the toxicological action of several heavy metal ions including cadmium , lead , mercury , and thallium can cause hypertension by affecting hormone metabolism , vasoconstriction , and renal tubular function .
NA
{ "id": "C0347988", "name": "heavy metal", "pos": [ 36, 47 ] }
{ "id": "C0025424", "name": "mercury", "pos": [ 80, 87 ] }
the toxicological action of several heavy metal ions including cadmium , lead , mercury , and thallium can cause hypertension by affecting hormone metabolism , vasoconstriction , and renal tubular function .
NA
{ "id": "C0347988", "name": "heavy metal", "pos": [ 36, 47 ] }
{ "id": "C0039738", "name": "thallium", "pos": [ 94, 102 ] }
incorporation of thymine , thymidine , adenine and uracil into nucleic acids of mycobacterium phlei and its phage .
NA
{ "id": "C0040087", "name": "thymine", "pos": [ 17, 24 ] }
{ "id": "C0041917", "name": "uracil", "pos": [ 51, 57 ] }
nevertheless , this compound does show some affinity for the tem-type penicillinases , cephalosporinases and a few other beta-lactamases .
NA
{ "id": "C0030841", "name": "penicillinases", "pos": [ 70, 84 ] }
{ "id": "C0597979", "name": "beta-lactamases", "pos": [ 121, 136 ] }
nevertheless , this compound does show some affinity for the tem-type penicillinases , cephalosporinases and a few other beta-lactamases .
NA
{ "id": "C0728805", "name": "cephalosporinases", "pos": [ 87, 104 ] }
{ "id": "C0597979", "name": "beta-lactamases", "pos": [ 121, 136 ] }
the colonization factor antigen ( cfa ) of strain 1373 is a new antigen ( which we propose to call cfa/iii ) and is distinct from cfa/i , cfa/ii and type 1 pili .
NA
{ "id": "C0003316", "name": "factor antigen", "pos": [ 17, 31 ] }
{ "id": "C0003320", "name": "cfa", "pos": [ 138, 141 ] }
during the present study , electrophoretic analysis of adenosine deaminase ( ada ) isozymes and radioimmunoassay for adcp in the primary fibroblasts and the transformed as well as certain tumor derived cell lines have demonstrated that adcp present in large quantities in the primary cells was absent or nearly absent in...
NA
{ "id": "C0016030", "name": "fibroblasts", "pos": [ 137, 148 ] }
{ "id": "C0007634", "name": "cells", "pos": [ 284, 289 ] }
a probe-patent foramen ovale was the presumed mechanism in four patients , and an unsuspected congenital atrial septal defect was found in the fifth patient .
NA
{ "id": "C0016522", "name": "patent foramen", "pos": [ 8, 22 ] }
{ "id": "C0018817", "name": "congenital", "pos": [ 94, 104 ] }
the bactericidal effects of chloramphenicol and three beta-lactams ( ampicillin , cefamandole , and penicillin g ) were measured for 27 strains of haemophilus influenzae type b isolated from the blood or cerebrospinal fluid of infected infants .
NA
{ "id": "C0002680", "name": "ampicillin", "pos": [ 69, 79 ] }
{ "id": "C0030827", "name": "penicillin g", "pos": [ 100, 112 ] }
a total of 229 clinical isolates of streptococcus pneumoniae recovered from 225 patients were serotyped and tested for susceptibility to penicillin g , ampicillin , mezlocillin , cefazolin , erythromycin , clindamycin , chloramphenicol , and sulfamethoxazole-trimethoprim .
NA
{ "id": "C0030827", "name": "penicillin g", "pos": [ 137, 149 ] }
{ "id": "C0002680", "name": "ampicillin", "pos": [ 152, 162 ] }
a total of 229 clinical isolates of streptococcus pneumoniae recovered from 225 patients were serotyped and tested for susceptibility to penicillin g , ampicillin , mezlocillin , cefazolin , erythromycin , clindamycin , chloramphenicol , and sulfamethoxazole-trimethoprim .
NA
{ "id": "C0002680", "name": "ampicillin", "pos": [ 152, 162 ] }
{ "id": "C0025893", "name": "mezlocillin", "pos": [ 165, 176 ] }
penicillin-resistant strains had higher minimal inhibitory concentrations of ampicillin , mezlocillin , and cefazolin than did penicillin-susceptible strains .
NA
{ "id": "C0002680", "name": "ampicillin", "pos": [ 77, 87 ] }
{ "id": "C0025893", "name": "mezlocillin", "pos": [ 90, 101 ] }
the binding of three aminoglycosides ( gentamicin , amikacin , streptomycin ) to the liposomes at ph 5.4 was also measured by gel permeation and was found to be related to the respective inhibitory potency of each drug .
NA
{ "id": "C0002556", "name": "aminoglycosides", "pos": [ 21, 36 ] }
{ "id": "C0017436", "name": "gentamicin", "pos": [ 39, 49 ] }
the binding of three aminoglycosides ( gentamicin , amikacin , streptomycin ) to the liposomes at ph 5.4 was also measured by gel permeation and was found to be related to the respective inhibitory potency of each drug .
NA
{ "id": "C0002556", "name": "aminoglycosides", "pos": [ 21, 36 ] }
{ "id": "C0038425", "name": "streptomycin", "pos": [ 63, 75 ] }