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The level of pH was dependent on frequency excitation , concentration of sodium potassium and hydrogen ions was changed after ouabain , 2,4-dinitrophenol , tetraethylammonium and tetrodotoxin effect .
{ "id": "C0429964", "pos": [ 20, 29 ], "name": "dependent" }
{ "id": "C0029904", "pos": [ 126, 133 ], "name": "ouabain" }
0NA
Reduced neck mobility does not seem to be as common after whiplash as in chronic CEH in general .
{ "id": "C0027530", "pos": [ 8, 12 ], "name": "neck" }
{ "id": "C0043145", "pos": [ 58, 66 ], "name": "whiplash" }
11finding_site_of
This review summarizes the findings to date of the protein-cell activities of these capsid proteins in the absence of the whole virus and their potential for therapeutic application with regard to the delivery of foreign molecules .
{ "id": "C0087111", "pos": [ 158, 169 ], "name": "therapeutic" }
{ "id": "C0011209", "pos": [ 201, 209 ], "name": "delivery" }
0NA
Ionizing irradiation of the esophagus results in development of esophagitis .
{ "id": "C0014876", "pos": [ 28, 37 ], "name": "esophagus" }
{ "id": "C0014868", "pos": [ 64, 75 ], "name": "esophagitis" }
11finding_site_of
Prior to elective caesarean section , 11.5 % used no prophylaxis , and 39.4 % used particulate antacids such as magnesium trisilicate mixture ( 33.3 % ) or Mylanta ( 6.1 % ) .
{ "id": "C0003138", "pos": [ 95, 103 ], "name": "antacids" }
{ "id": "C0007876", "pos": [ 18, 35 ], "name": "caesarean section" }
0NA
Isolated mitochondria swelled when added to an isosmotic solution of proline , serine , methionine , threonine , alanine , and glycine .
{ "id": "C0038999", "pos": [ 22, 29 ], "name": "swelled" }
{ "id": "C0025646", "pos": [ 88, 98 ], "name": "methionine" }
0NA
Basipetal transport is not affected by destruction of the tissue but markedly inhibited by the other treatments .
{ "id": "C1261381", "pos": [ 39, 50 ], "name": "destruction" }
{ "id": "C0040300", "pos": [ 58, 64 ], "name": "tissue" }
0NA
All except one patient were given 11 - 19 mg of intravenous dexamethasone before docetaxel infusion .
{ "id": "C0246415", "pos": [ 81, 90 ], "name": "docetaxel" }
{ "id": "C0574032", "pos": [ 91, 99 ], "name": "infusion" }
0NA
Biopsy of clinically normal skin to demonstrate giant pigment granules is the most accurate means of diagnosis .
{ "id": "C0005558", "pos": [ 0, 6 ], "name": "Biopsy" }
{ "id": "C0017547", "pos": [ 48, 53 ], "name": "giant" }
0NA
Among other proteins , Hsp90 was found upregulated upon ATP stimulation .
{ "id": "C1292856", "pos": [ 60, 71 ], "name": "stimulation" }
{ "id": "C0033684", "pos": [ 12, 20 ], "name": "proteins" }
0NA
These findings demonstrated that glycyrrhizin treatment enhanced the antioxidant status and decreased the incidence of free radical-induced lipid peroxidation and improved immunity activities in the blood and nasal mucosa of AR mice .
{ "id": "C0005767", "pos": [ 199, 204 ], "name": "blood" }
{ "id": "C0027428", "pos": [ 209, 221 ], "name": "nasal mucosa" }
0NA
Guinea pig inclusion conjunctivitis ( GPIC ) , an analogous disease of guinea pigs , provides a useful , less expensive model to study ocular chlamydial infections .
{ "id": "C0015392", "pos": [ 135, 141 ], "name": "ocular" }
{ "id": "C0008149", "pos": [ 142, 163 ], "name": "chlamydial infections" }
0NA
Clinical data suggest an association of increased serum androgens with cardiovascular mortality in females , but not in males .
{ "id": "C0007226", "pos": [ 71, 85 ], "name": "cardiovascular" }
{ "id": "C0086287", "pos": [ 99, 106 ], "name": "females" }
0NA
Eleven studies that used operant or respondent conditioning procedures in the treatment of seizure disorders were evaluated primarily with respect to methodological considerations and secondarily with respect to procedure and outcome .
{ "id": "C0184661", "pos": [ 212, 221 ], "name": "procedure" }
{ "id": "C0014544", "pos": [ 91, 108 ], "name": "seizure disorders" }
0NA
A thorough understanding of the naturally occurring events in the immune system in response to carcinogenesis will facilitate the development of strategies for the immunoprevention of cancer .
{ "id": "C0020962", "pos": [ 66, 79 ], "name": "immune system" }
{ "id": "C0006826", "pos": [ 184, 190 ], "name": "cancer" }
0NA
Warfarin is more effective than aspirin but is used less often than indicated because of hemorrhagic risk and the inconvenience of coagulation monitoring .
{ "id": "C0004057", "pos": [ 32, 39 ], "name": "aspirin" }
{ "id": "C0043031", "pos": [ 0, 8 ], "name": "Warfarin" }
0NA
These findings extended our previous results of gender differences in regional brain activation during response inhibition .
{ "id": "C0006104", "pos": [ 79, 84 ], "name": "brain" }
{ "id": "C0079399", "pos": [ 48, 54 ], "name": "gender" }
0NA
The remaining 35 women each had prolonged amenorrhea and were found to have an atrophic inactive endometrium .
{ "id": "C0002453", "pos": [ 42, 52 ], "name": "amenorrhea" }
{ "id": "C0014180", "pos": [ 97, 108 ], "name": "endometrium" }
0NA
Over the time course of the disease , gait and balance disorders worsen and become resistant to pharmacological and surgical treatments .
{ "id": "C0012634", "pos": [ 28, 35 ], "name": "disease" }
{ "id": "C0543467", "pos": [ 116, 135 ], "name": "surgical treatments" }
0NA
Lamellar keratoplasty was the first procedure described .
{ "id": "C0184661", "pos": [ 36, 45 ], "name": "procedure" }
{ "id": "C0022591", "pos": [ 0, 21 ], "name": "Lamellar keratoplasty" }
0NA
Survivors of traumatic brain injury often have long-term sensory , cognitive and motor deficits that may impair vehicle operation .
{ "id": "C0876926", "pos": [ 13, 35 ], "name": "traumatic brain injury" }
{ "id": "C0543467", "pos": [ 120, 129 ], "name": "operation" }
0NA
Administration of exogenous vasopressin resulted in an increase in urine specific gravity and urine osmolality , a decrease in serum osmolality , and a normalization of serum sodium concentrations .
{ "id": "C0229671", "pos": [ 127, 132 ], "name": "serum" }
{ "id": "C0086741", "pos": [ 133, 143 ], "name": "osmolality" }
0NA
We used IPD from the Meta-Analysis of Chemotherapy in Nasopharynx Carcinoma ( MAC-NPC ) and its updated version MAC-NPC2 for illustration that included respectively 1,975 and 5,028 patients in 11 and 23 comparisons .
{ "id": "C0013216", "pos": [ 38, 50 ], "name": "Chemotherapy" }
{ "id": "C2931822", "pos": [ 54, 75 ], "name": "Nasopharynx Carcinoma" }
0NA
Age , sex , coronary risk factors , including hypertension , diabetes mellitus ( DM ) , dyslipidemia , and smoking were investigated as predictors for CT-HRP on multivariate analysis using logistic regression analysis .
{ "id": "C0011849", "pos": [ 61, 78 ], "name": "diabetes mellitus" }
{ "id": "C0020538", "pos": [ 46, 58 ], "name": "hypertension" }
0NA
Although , in both cases , the biopsy specimens of the gastric neoplasm proved moderately to poorly differentiated adenocarcinoma without hepatoid differentiation , the localization of Glypican 3 in gastric cancer cells was observed using immunostaining with a monoclonal antibody .
{ "id": "C0005558", "pos": [ 31, 37 ], "name": "biopsy" }
{ "id": "C0038356", "pos": [ 55, 71 ], "name": "gastric neoplasm" }
0NA
We report the cases of four patients who were taking the anticonvulsant drugs phenytoin or carbamazepine and in whom skin lesions developed that showed histologic features suggestive of mycosis fungoides .
{ "id": "C0003286", "pos": [ 57, 77 ], "name": "anticonvulsant drugs" }
{ "id": "C0006949", "pos": [ 91, 104 ], "name": "carbamazepine" }
0NA
The influence of frequently used pharmaceutical excipients , i.e. alcohols ( ethanol , glycerol , propylene glycol ) , buffers ( phosphate , citrate ) and tonicity modulators ( NaCl , MgCl2 ) was evaluated by phase solubility , absorption and fluorescence emission spectra and fluorescence lifetime studies .
{ "id": "C0017861", "pos": [ 87, 95 ], "name": "glycerol" }
{ "id": "C0001962", "pos": [ 77, 84 ], "name": "ethanol" }
0NA
Regulation of ion channel activity plays a central role in controlling heart rate , rhythm , and contractility responses to cardiovascular demands .
{ "id": "C0007226", "pos": [ 124, 138 ], "name": "cardiovascular" }
{ "id": "C0018810", "pos": [ 71, 81 ], "name": "heart rate" }
0NA
The hormone , calcitonin , has the potential to relieve pain , and also retain bone density , thus reducing the risk of fractures .
{ "id": "C0019932", "pos": [ 4, 11 ], "name": "hormone" }
{ "id": "C0016658", "pos": [ 120, 129 ], "name": "fractures" }
0NA
There was no significant correlation between the duration of IJV removal and IOP ( p=0.8 ) .
{ "id": "C0015252", "pos": [ 65, 72 ], "name": "removal" }
{ "id": "C0578862", "pos": [ 77, 80 ], "name": "IOP" }
0NA
Thirty-eight eyes of 30 patients were enrolled , including a total of 54 intravitreal injections of methotrexate at a dose of 400 µg in 0.1 mL. The primary outcome measure was visual acuity .
{ "id": "C0015392", "pos": [ 13, 17 ], "name": "eyes" }
{ "id": "C0042812", "pos": [ 176, 189 ], "name": "visual acuity" }
0NA
Since then , the constituents of hormonal OCs have changed and now contain lower doses of oestrogen and progestagen .
{ "id": "C0014939", "pos": [ 90, 99 ], "name": "oestrogen" }
{ "id": "C0033306", "pos": [ 104, 115 ], "name": "progestagen" }
0NA
However , destruction of cervical vertebrae and myelopathy progressed secondary to repeated microfractures from mechanical stress .
{ "id": "C1261381", "pos": [ 10, 21 ], "name": "destruction" }
{ "id": "C0728985", "pos": [ 25, 43 ], "name": "cervical vertebrae" }
0NA
The results showed consistent reductions in forward tongue movement during consonant closure in the ingressive conditions .
{ "id": "C0185003", "pos": [ 85, 92 ], "name": "closure" }
{ "id": "C0026649", "pos": [ 59, 67 ], "name": "movement" }
0NA
The hypothesis was originally proposed based on biochemical activities of the aminoquinolines ( e.g. , pamaquine ( plasmoquine(TM ) ) , primaquine and chloroquine ) , but recent publications demonstrated that some of these drugs definitely adversely affect HIV and other viruses and logically would cause them to evolve resistance .
{ "id": "C0013227", "pos": [ 223, 228 ], "name": "drugs" }
{ "id": "C0033126", "pos": [ 136, 146 ], "name": "primaquine" }
0NA
Among these patients , 40 cases manifested as gastrointestinal bleeding , 7 had iron deficiency anemia , 6 had chronic abdominal pain , and 2 showed abdominal distension or discomfort .
{ "id": "C0000731", "pos": [ 149, 169 ], "name": "abdominal distension" }
{ "id": "C0232491", "pos": [ 111, 133 ], "name": "chronic abdominal pain" }
0NA
All five cases who became pregnant had been taking an antibiotic ( microcycline or a cephalosporin ) for at least 3 months .
{ "id": "C0549206", "pos": [ 26, 34 ], "name": "pregnant" }
{ "id": "C3536856", "pos": [ 85, 98 ], "name": "cephalosporin" }
0NA
The main features of the disease are normochromic and macrocytic anemia , reticulocytopenia , and nearly absent erythroid progenitors in the bone marrow .
{ "id": "C0005953", "pos": [ 141, 152 ], "name": "bone marrow" }
{ "id": "C0012634", "pos": [ 25, 32 ], "name": "disease" }
0NA
By compilation in a " composite curve " of the hemoglobin and radioactivity CCD profiles obtained for each erythrocyte population , the distribution of cells according to age can be inferred .
{ "id": "C0019046", "pos": [ 47, 57 ], "name": "hemoglobin" }
{ "id": "C0008928", "pos": [ 76, 79 ], "name": "CCD" }
0NA
The main neuropathological feature in Parkinson 's disease ( PD ) is a severe degeneration of the dopaminergic neurons in the substantia nigra resulting in a loss of dopamine in the striatum .
{ "id": "C0282151", "pos": [ 98, 110 ], "name": "dopaminergic" }
{ "id": "C0013030", "pos": [ 166, 174 ], "name": "dopamine" }
16is_modification_of
In this study , human MSC derived from many adult ( bone marrow and adipose tissue ) or fetal ( cord blood , Wharton 's jelly , umbilical cord perivascular compartment and amniotic fluid ) tissues were investigated .
{ "id": "C0005953", "pos": [ 52, 63 ], "name": "bone marrow" }
{ "id": "C0040300", "pos": [ 189, 196 ], "name": "tissues" }
0NA
The best spectacle-corrected visual acuity was unchanged ( 8 % ) or improved ( 92 % ) in all eyes compared with the preoperative levels .
{ "id": "C0015392", "pos": [ 93, 97 ], "name": "eyes" }
{ "id": "C0042812", "pos": [ 29, 42 ], "name": "visual acuity" }
0NA
The clinical significance of the hepatitis B virus core-related antigen ( HBcrAg ) assay in monitoring the antiviral effects of lamivudine is reviewed .
{ "id": "C0209738", "pos": [ 128, 138 ], "name": "lamivudine" }
{ "id": "C0150369", "pos": [ 92, 102 ], "name": "monitoring" }
0NA
In conclusion , these results demonstrate for the first time that EA enhances myelin debris removal from activated microglia after demyelination , and promotes remyelination .
{ "id": "C0011304", "pos": [ 131, 144 ], "name": "demyelination" }
{ "id": "C0015252", "pos": [ 92, 99 ], "name": "removal" }
0NA
Reperfusion injury was a risk factor for death but not for amputation ( OR 16.9 , 95 % CI 1.1 - 232.9 ) after adjustment for age , duration of occlusion , and diabetes .
{ "id": "C0011065", "pos": [ 41, 46 ], "name": "death" }
{ "id": "C0002688", "pos": [ 59, 69 ], "name": "amputation" }
0NA
Subsequently , dislocations of the right and the left knee joint were surgically treated at 16 and 20 months , respectively , by reduction and transfixation with Kirschner 's wires according to Niebauer and King .
{ "id": "C0012691", "pos": [ 15, 27 ], "name": "dislocations" }
{ "id": "C0543467", "pos": [ 70, 80 ], "name": "surgically" }
0NA
Laryngeal involvement most frequently involves the supraglottis and presents with dyspnea .
{ "id": "C0023078", "pos": [ 0, 9 ], "name": "Laryngeal" }
{ "id": "C2239273", "pos": [ 51, 63 ], "name": "supraglottis" }
0NA
Only micro-sampling of 20 μL blood was needed for the analysis , and the pretreatment procedure including blood collection , derivatization by 10-ethyl-acridine-3-sulfonyl chloride ( EASC ) and injection to the sampling vials was efficiently finished in 10 min with no cumbersome and complicated operation .
{ "id": "C0005767", "pos": [ 29, 34 ], "name": "blood" }
{ "id": "C0021485", "pos": [ 194, 203 ], "name": "injection" }
0NA
HisB10 is doubly protonated not only at pD6.6 but also at pD9 , indicating an abnormal pK(a ) of this histidine .
{ "id": "C0205161", "pos": [ 78, 86 ], "name": "abnormal" }
{ "id": "C0019602", "pos": [ 102, 111 ], "name": "histidine" }
0NA
Enamel fractures were the most common type ( 74.8 % ) , followed by enamel and dentin ( 11.7 % ) .
{ "id": "C0011350", "pos": [ 68, 74 ], "name": "enamel" }
{ "id": "C0436032", "pos": [ 0, 16 ], "name": "Enamel fractures" }
11finding_site_of
Stimulation of the pedunculo-pontine tegmental nuclei ( which provide cholinergic innervation to the brain stem and subcortical nuclei ) has also been used with some success for the treatment of gait dysfunction .
{ "id": "C1292856", "pos": [ 0, 11 ], "name": "Stimulation" }
{ "id": "C0006121", "pos": [ 101, 111 ], "name": "brain stem" }
0NA
After hemostasis is achieved and bleeding has stopped , longer-term decisions to recommence antithrombotic agents can be challenging , especially in older people .
{ "id": "C0019080", "pos": [ 33, 41 ], "name": "bleeding" }
{ "id": "C0019116", "pos": [ 6, 16 ], "name": "hemostasis" }
0NA
In general , among the 105 cases with CKD ( stages 3 and 4)-MBD were clinically characterized by mild changes in serum bone metabolic markers ; And their main TCM syndrome was the deficiency in spleen and kidney .
{ "id": "C0022646", "pos": [ 205, 211 ], "name": "kidney" }
{ "id": "C1561643", "pos": [ 38, 41 ], "name": "CKD" }
11finding_site_of
In an era when the length of hospitalization has a major impact on health care costs , the determination of the optimal duration of the infusion of these drugs after PCI is of great relevance .
{ "id": "C0013227", "pos": [ 154, 159 ], "name": "drugs" }
{ "id": "C0574032", "pos": [ 136, 144 ], "name": "infusion" }
0NA
The infusion of crude venom tended to reduce PP , although the effect was not significant , whereas with crotoxin PP remained stable during the 100 min of perfusion .
{ "id": "C0574032", "pos": [ 4, 12 ], "name": "infusion" }
{ "id": "C0031001", "pos": [ 155, 164 ], "name": "perfusion" }
0NA
The results suggest that FTC renal transport is likely mediated by a CMD-sensitive organic cation transporter ( OCT ) in the kidney .
{ "id": "C0022646", "pos": [ 125, 131 ], "name": "kidney" }
{ "id": "C0206682", "pos": [ 25, 28 ], "name": "FTC" }
0NA
The performance of pancreaticoduodenectomy improves as surgical experience is gained .
{ "id": "C0085162", "pos": [ 19, 42 ], "name": "pancreaticoduodenectomy" }
{ "id": "C0543467", "pos": [ 55, 63 ], "name": "surgical" }
0NA
The frontal regions , which were identified to be transitional points , projected causal effects to the occipital lobe , temporal regions , and the cerebellum and received causal effects from the thalamus ( P < .05 , false discovery rate corrected ) .
{ "id": "C0007765", "pos": [ 148, 158 ], "name": "cerebellum" }
{ "id": "C0016733", "pos": [ 4, 19 ], "name": "frontal regions" }
0NA
The aim of the study was to evaluate in vitro activity of daptomycin combinations with rifampicin , gentamicin , fosfomycin , and fusidic acid against MRSA strains .
{ "id": "C3854019", "pos": [ 100, 110 ], "name": "gentamicin" }
{ "id": "C0080194", "pos": [ 156, 163 ], "name": "strains" }
0NA
In spite of mild prolongation in the postoperative bleeding times and moderate thrombocytopenia , DDAVP had no beneficial effect on blood loss or transfusion requirements .
{ "id": "C0019080", "pos": [ 132, 142 ], "name": "blood loss" }
{ "id": "C0032788", "pos": [ 37, 59 ], "name": "postoperative bleeding" }
3associated_morphology_of
Many took part in groups related to problems and resources associated with injecting drugs , religion , sports or gender .
{ "id": "C0013227", "pos": [ 85, 90 ], "name": "drugs" }
{ "id": "C0079399", "pos": [ 114, 120 ], "name": "gender" }
0NA
Dermatofibrosarcoma protuberans ( DFSP ) is a low-grade malignant soft tissue tumor of subcutaneous tissues that has a propensity for local recurrence ; however , it seldom metastasizes .
{ "id": "C0278403", "pos": [ 87, 107 ], "name": "subcutaneous tissues" }
{ "id": "C0392784", "pos": [ 34, 38 ], "name": "DFSP" }
0NA
Mandibular teeth erupted earlier than maxillary opposing teeth in both sexes , except upper premolars .
{ "id": "C0024947", "pos": [ 38, 47 ], "name": "maxillary" }
{ "id": "C0227029", "pos": [ 0, 16 ], "name": "Mandibular teeth" }
0NA
The alteration in sinusoidal collagen type IV occurrence , and myofibroblastic ( alpha-SMA-positive ) Ito cellular transformation are described in the liver of patients with malignant gastric and colorectal tumors , using electron microscopy as well as light microscopical and ultrastructural immunohistochemistry .
{ "id": "C0023884", "pos": [ 151, 156 ], "name": "liver" }
{ "id": "C0009404", "pos": [ 196, 213 ], "name": "colorectal tumors" }
0NA
Total hysterectomy and bilateral salpingo-oophorectomy were performed , and a hemispheric tumor , measuring 2.7 x 2.5 x 1.8 cm , was found protruding into the uterine cavity of the upper uterine segment .
{ "id": "C0447619", "pos": [ 181, 202 ], "name": "upper uterine segment" }
{ "id": "C0677962", "pos": [ 0, 18 ], "name": "Total hysterectomy" }
0NA
These results can be explained by the concentration of thrombin in the thrombus and improved inhibition by the low-molecular-weight compounds .
{ "id": "C0087086", "pos": [ 71, 79 ], "name": "thrombus" }
{ "id": "C0040018", "pos": [ 55, 63 ], "name": "thrombin" }
0NA
Standard surgical resection was performed 1 to 4 weeks after cryoablation .
{ "id": "C0015252", "pos": [ 9, 27 ], "name": "surgical resection" }
{ "id": "C0010408", "pos": [ 61, 73 ], "name": "cryoablation" }
0NA
Forty-two patients were still alive 6 months after operation , and we studied their pulmonary function at the short and long term .
{ "id": "C2584946", "pos": [ 30, 35 ], "name": "alive" }
{ "id": "C0543467", "pos": [ 51, 60 ], "name": "operation" }
0NA
Need for postoperative inotropic support was recorded , as was oxygen index prior to and after tracheal extubation .
{ "id": "C0040578", "pos": [ 95, 103 ], "name": "tracheal" }
{ "id": "C0553891", "pos": [ 104, 114 ], "name": "extubation" }
13indirect_procedure_site_of
However , the quantity of mineralized callus was significantly greater in the treated than untreated bones .
{ "id": "C0262950", "pos": [ 101, 106 ], "name": "bones" }
{ "id": "C0006767", "pos": [ 38, 44 ], "name": "callus" }
11finding_site_of
Patients with history of lung pathology , such as COPD , who experience retching and cough during transesophageal echocardiography may be more susceptible to embolization of pre-existing thrombi .
{ "id": "C0024109", "pos": [ 25, 29 ], "name": "lung" }
{ "id": "C0206054", "pos": [ 98, 130 ], "name": "transesophageal echocardiography" }
0NA
NO decreases PVR via cGMP , and PGI2 produces pulmonary vasodilation via cAMP .
{ "id": "C0033567", "pos": [ 32, 36 ], "name": "PGI2" }
{ "id": "C0242852", "pos": [ 13, 16 ], "name": "PVR" }
0NA
The study included 75 females who underwent hysterectomy for benign pelvic lesions .
{ "id": "C0221198", "pos": [ 75, 82 ], "name": "lesions" }
{ "id": "C0086287", "pos": [ 22, 29 ], "name": "females" }
0NA
The results show that the PMoV retains its parent structure after encapsulation by starch and lipid nanoparticles .
{ "id": "C0023779", "pos": [ 94, 99 ], "name": "lipid" }
{ "id": "C0038179", "pos": [ 83, 89 ], "name": "starch" }
0NA
The temperature range for specific thermoregulatory responses ( shivering , sweat secretion ) of the high altitude residents is narrower than in the lowland inhabitants , as well as the sensitivity of temperature centres of the formers is lower than in the latters .
{ "id": "C0020517", "pos": [ 186, 197 ], "name": "sensitivity" }
{ "id": "C0005903", "pos": [ 4, 15 ], "name": "temperature" }
0NA
In this study , the scanning laser ophthalmoscope ( SLO ) was used , combined with fluorescein angiography , to measure retinal blood flow indices in HIV seropositive patients .
{ "id": "C0035298", "pos": [ 120, 127 ], "name": "retinal" }
{ "id": "C0392288", "pos": [ 20, 49 ], "name": "scanning laser ophthalmoscope" }
0NA
The virus released from the persistently infected cells developed an altered cloudy or " bull's-eye " plaque morphology with increasing passage level , and a greater temperature sensitivity at 39.5 degrees than standard virus .
{ "id": "C0020517", "pos": [ 178, 189 ], "name": "sensitivity" }
{ "id": "C0005903", "pos": [ 166, 177 ], "name": "temperature" }
0NA
The occurrence of arrhythmias was studied in the " calcium-paradox " model in the isolated rat heart .
{ "id": "C0018787", "pos": [ 95, 100 ], "name": "heart" }
{ "id": "C0003811", "pos": [ 18, 29 ], "name": "arrhythmias" }
11finding_site_of
Overall , this study provides a useful method for detecting BAL in medicines , enabling in vivo visualization research .
{ "id": "C0013227", "pos": [ 67, 76 ], "name": "medicines" }
{ "id": "C0012383", "pos": [ 60, 63 ], "name": "BAL" }
0NA
Because of the possibility of severe bone marrow depression , 6-thioguanine is not a first-line treatment .
{ "id": "C0205082", "pos": [ 30, 36 ], "name": "severe" }
{ "id": "C0039902", "pos": [ 62, 75 ], "name": "6-thioguanine" }
0NA
None of the substances influenced the general locomotor activity significantly , but the higher doses of buspirone mainly blocked the closed-arm entries and they even decreased the total distance traveled .
{ "id": "C0028778", "pos": [ 122, 129 ], "name": "blocked" }
{ "id": "C0006462", "pos": [ 105, 114 ], "name": "buspirone" }
0NA
The authors describe two cases of esophageal duplication resected via a left thoracoscopic approach .
{ "id": "C0015252", "pos": [ 57, 65 ], "name": "resected" }
{ "id": "C0266135", "pos": [ 34, 56 ], "name": "esophageal duplication" }
0NA
We collected data concerning 543 typhoid ileal perforations which represented 29.0 % of all peritonitis .
{ "id": "C0549099", "pos": [ 47, 59 ], "name": "perforations" }
{ "id": "C0020885", "pos": [ 41, 46 ], "name": "ileal" }
0NA
A substantial minority of patients who survive an acquired brain injury develop a state of sympathetic hyperactivity that can persist for weeks or months , consisting of periodic episodes of increased heart rate and blood pressure , sweating , hyperthermia , and motor posturing , often in response to external stimuli .
{ "id": "C0015967", "pos": [ 244, 256 ], "name": "hyperthermia" }
{ "id": "C0038990", "pos": [ 233, 241 ], "name": "sweating" }
0NA
In an asphyxial cardiac arrest rat model , administration of VPA improved neurologic outcomes and added a neuroprotective effect to HT .
{ "id": "C0042291", "pos": [ 61, 64 ], "name": "VPA" }
{ "id": "C0018790", "pos": [ 16, 30 ], "name": "cardiac arrest" }
0NA
In situ hybridization studies demonstrated the expression of S-endoglin in the endothelium from human arteries .
{ "id": "C0003842", "pos": [ 102, 110 ], "name": "arteries" }
{ "id": "C0014257", "pos": [ 79, 90 ], "name": "endothelium" }
0NA
Experimental uveitis is characterized by a pronounced lipid peroxidation ( LPO ) in damaged tissues of eye , which is complicated by reduced activity of the antioxidant enzymes , SOD and catalase .
{ "id": "C0015392", "pos": [ 103, 106 ], "name": "eye" }
{ "id": "C0040300", "pos": [ 92, 99 ], "name": "tissues" }
0NA
While pharmacotherapy holds the potential for significant benefit in young children with ADHD , concerns with variation in response and tolerability highlight the need for careful evaluation , close monitoring , and an ongoing risk/benefit analysis throughout the implementation and use of medication .
{ "id": "C0013227", "pos": [ 290, 300 ], "name": "medication" }
{ "id": "C0013216", "pos": [ 6, 21 ], "name": "pharmacotherapy" }
10direct_substance_of
It was selectively done in the latter vessel through the brachial artery after the Seldinger method .
{ "id": "C0005847", "pos": [ 38, 44 ], "name": "vessel" }
{ "id": "C0006087", "pos": [ 57, 72 ], "name": "brachial artery" }
0NA
Two short-term experiments were conducted with mixed phytoplankton populations dominated by C. raciborskii in a subtropical reservoir where treatments had nitrate ( NO3 ) , urea ( U ) and inorganic phosphorus ( P ) added alone or in combination .
{ "id": "C0041942", "pos": [ 173, 177 ], "name": "urea" }
{ "id": "C0087111", "pos": [ 140, 150 ], "name": "treatments" }
0NA
The commonest allergens responsible were nickel ( 17.7 % ) , fragrance ( 13.3 % ) , neomycin ( 6.9 % ) , colophony ( 6.6 % ) and proflavine ( 6.5 % ) .
{ "id": "C0027603", "pos": [ 84, 92 ], "name": "neomycin" }
{ "id": "C0033294", "pos": [ 129, 139 ], "name": "proflavine" }
0NA
Staphylococcus aureus - a commensal of the human skin , nares and gastrointestinal tract - is also a leading cause of bacterial skin and soft tissue infection ( SSTIs ) , bacteremia , sepsis , peritonitis , pneumonia and endocarditis .
{ "id": "C0017189", "pos": [ 66, 88 ], "name": "gastrointestinal tract" }
{ "id": "C0014118", "pos": [ 221, 233 ], "name": "endocarditis" }
0NA
Owing to the small sample size , the limits of agreement straddled zero at all time points , although the lower limit was close to zero during treatment ( finger measurement appeared to be higher than venous measurement on room air and lower than venous undergoing HBOT ) .
{ "id": "C0042449", "pos": [ 247, 253 ], "name": "venous" }
{ "id": "C0429870", "pos": [ 201, 219 ], "name": "venous measurement" }
0NA
The optimum conditions obtained through the overlapped contour plot were as follows : ethanol concentration of 59 % , extraction time of 46.57min , and temperature of 66.22 ° C .
{ "id": "C0001962", "pos": [ 86, 93 ], "name": "ethanol" }
{ "id": "C0005903", "pos": [ 152, 163 ], "name": "temperature" }
0NA
Tenotomy of the rabbit eye causes microvascular change similar to that in occlusion of the long posterior ciliary arteries .
{ "id": "C0001168", "pos": [ 74, 83 ], "name": "occlusion" }
{ "id": "C0226178", "pos": [ 91, 122 ], "name": "long posterior ciliary arteries" }
0NA
FFA plasma concentration and composition may represent one of the factors accounting for high heterogeneity of conclusions concerning the effect of the Pro12Ala on BMI , insulin sensitivity or diabetes type 2 ( DM2 ) susceptibility .
{ "id": "C0011860", "pos": [ 193, 208 ], "name": "diabetes type 2" }
{ "id": "C0020517", "pos": [ 178, 189 ], "name": "sensitivity" }
0NA
If MRI and SPECT were considered together , the sensitivity was 92.3 % in hyposmia and 92 % in anosmia , but the specificity was 87 % in both cases .
{ "id": "C0024485", "pos": [ 3, 6 ], "name": "MRI" }
{ "id": "C0040399", "pos": [ 11, 16 ], "name": "SPECT" }
0NA
In addition , it is demonstrated that the deleterious association for radon and lung cancer observed in residential and miner studies is consistent with negative trends from ecological studies , of the type described by Cohen .
{ "id": "C0205160", "pos": [ 153, 161 ], "name": "negative" }
{ "id": "C0242379", "pos": [ 80, 91 ], "name": "lung cancer" }
0NA
The heuristic value of these models is set into balance to the danger of their misuse for nailing down somebody about quality and duration of his " Trauerarbeit " .
{ "id": "C0021885", "pos": [ 90, 97 ], "name": "nailing" }
{ "id": "C0014653", "pos": [ 48, 55 ], "name": "balance" }
0NA
Prominent expression was also detected on tegumental surface of the parasite and on epical surface of bile duct epithelium indicates their additional role in host-parasite interaction .
{ "id": "C0442726", "pos": [ 30, 38 ], "name": "detected" }
{ "id": "C0037420", "pos": [ 172, 183 ], "name": "interaction" }
0NA