text stringlengths 18 770 | h dict | t dict | relation class label 22 classes |
|---|---|---|---|
Attention should be paid to avoidance intra-operative bleeding or cranial nerves damage . | {
"id": "C0010957",
"pos": [
81,
87
],
"name": "damage"
} | {
"id": "C0010268",
"pos": [
66,
80
],
"name": "cranial nerves"
} | 0NA |
The lower leg is immobilized in a cast for at least 2 weeks postoperatively ; additional procedures require an extended period of immobilization . | {
"id": "C1140621",
"pos": [
4,
13
],
"name": "lower leg"
} | {
"id": "C0025344",
"pos": [
120,
126
],
"name": "period"
} | 0NA |
Markers of the systemic inflammatory response to infection could include cytokines such as tumour necrosis factor alpha , interleukin 1 , 6 and 8 and the propeptide procalcitonin . | {
"id": "C1456820",
"pos": [
91,
119
],
"name": "tumour necrosis factor alpha"
} | {
"id": "C0009450",
"pos": [
49,
58
],
"name": "infection"
} | 0NA |
In primary Sjögren 's syndrome ( pSS ) and systemic lupus erythematosus ( SLE ) anti-cN-1A autoantibodies can be detected as well . | {
"id": "C0004358",
"pos": [
91,
105
],
"name": "autoantibodies"
} | {
"id": "C0036421",
"pos": [
33,
36
],
"name": "pSS"
} | 0NA |
In this review , we systematically performed a meta-analysis for the use of photodynamic therapy in circumscribed choroidal hemangioma , diffuse choroidal hemangioma , retinal capillary hemangioma , von Hippel-Lindau angiomatosis , choroidal melanoma , retinal astrocytoma , retinoblastoma , eyelid tumors , conjunctival tumors , and choroidal metastasis . | {
"id": "C0035298",
"pos": [
253,
260
],
"name": "retinal"
} | {
"id": "C0730303",
"pos": [
168,
196
],
"name": "retinal capillary hemangioma"
} | 11finding_site_of |
Thus far , human papillomavirus virus-like particle vaccines have proven to be clinically efficacious in the early trials looking at the prevention of infection . | {
"id": "C0199176",
"pos": [
137,
147
],
"name": "prevention"
} | {
"id": "C0042210",
"pos": [
52,
60
],
"name": "vaccines"
} | 0NA |
Minimum inhibitory concentrations ( MIC ) of the prescribed drugs were measured for representative isolates before and after treatment . | {
"id": "C0013227",
"pos": [
60,
65
],
"name": "drugs"
} | {
"id": "C0427978",
"pos": [
0,
33
],
"name": "Minimum inhibitory concentrations"
} | 0NA |
Removal of drinking water at the start of the dark period reduced food intake in freely feeding rats within 45 min . | {
"id": "C0015252",
"pos": [
0,
7
],
"name": "Removal"
} | {
"id": "C0013470",
"pos": [
66,
77
],
"name": "food intake"
} | 0NA |
Collectively , our findings indicate that IYG-Tech impacts some determinants of sexual behavior , and that additional efficacy evaluation with full intervention exposure may be warranted . | {
"id": "C0184661",
"pos": [
148,
160
],
"name": "intervention"
} | {
"id": "C0274281",
"pos": [
161,
169
],
"name": "exposure"
} | 0NA |
Etiologies of these patients included failed prior surgery , rheumatoid arthritis , congenital anomalies and old odontoid fractures . | {
"id": "C0000768",
"pos": [
84,
104
],
"name": "congenital anomalies"
} | {
"id": "C0003873",
"pos": [
61,
81
],
"name": "rheumatoid arthritis"
} | 0NA |
In addition , CD4(+ ) regulatory T cells are required to maintain self-tolerance and to inhibit immune responses that could damage the host . | {
"id": "C0010957",
"pos": [
126,
132
],
"name": "damage"
} | {
"id": "C0301872",
"pos": [
98,
114
],
"name": "immune responses"
} | 0NA |
Efficacy of trastuzumab in the adjuvant setting seems to be increased if administered concomitantly with chemotherapy instead of sequentially . | {
"id": "C0013216",
"pos": [
105,
117
],
"name": "chemotherapy"
} | {
"id": "C0728747",
"pos": [
12,
23
],
"name": "trastuzumab"
} | 0NA |
Specifically the mean amplitude of mfVEP in POAG eyes was estimated at 34.2 ± 17.6 nV/deg2 , 6.9 ± 4.8 nV/deg2 and 2.6 ± 1.6 nV/deg2 in rings 1 , 2 and 3 respectively . | {
"id": "C0015392",
"pos": [
49,
53
],
"name": "eyes"
} | {
"id": "C0339573",
"pos": [
44,
48
],
"name": "POAG"
} | 11finding_site_of |
Specifically , the onset of lip movement toward the intervocalic consonant was found to be constant with respect to the vowel-to-vowel jaw cycle in both time and relative phasing . | {
"id": "C0023759",
"pos": [
28,
31
],
"name": "lip"
} | {
"id": "C0026649",
"pos": [
32,
40
],
"name": "movement"
} | 0NA |
No significant changes were detected in the spontaneous sinus or junctional cycle length , junctional recovery times at a fixed pacing cycle length , blood pressure , or circulating catecholamine concentrations during the control day . | {
"id": "C0442726",
"pos": [
28,
36
],
"name": "detected"
} | {
"id": "C0005823",
"pos": [
150,
164
],
"name": "blood pressure"
} | 0NA |
Demographic , clinical , and healthcare resource utilization data on patients with herpes zoster or post-herpetic neuralgia collected via case report forms were used to estimate direct medical cost . | {
"id": "C0032768",
"pos": [
100,
123
],
"name": "post-herpetic neuralgia"
} | {
"id": "C0019360",
"pos": [
83,
96
],
"name": "herpes zoster"
} | 18occurs_after |
Although atopic dermatitis is the most common inflammatory dermatosis affecting children , no previous studies have evaluated the relationship between disease severity and the referral pattern to secondary health care services . | {
"id": "C0011615",
"pos": [
9,
26
],
"name": "atopic dermatitis"
} | {
"id": "C3875321",
"pos": [
46,
69
],
"name": "inflammatory dermatosis"
} | 0NA |
For mice infected with 10(4 ) parasites , the drugs combined at the lowest and highest doses ( 5 plus 25 and 100 plus 400 mg/kg/day ) were , similarly , more effective than ATO alone ( P = 0.035 and 0.000 , respectively ) but not than CLI alone ( P > 0 . 05 ) . | {
"id": "C0013227",
"pos": [
46,
51
],
"name": "drugs"
} | {
"id": "C0052416",
"pos": [
173,
176
],
"name": "ATO"
} | 0NA |
As one of the major forms of inflammatory bowel disease , ulcerative colitis pathophysiology is characterized by an aberrant intestinal inflammatory response that persists causing chronic inflammation and tissue injury . | {
"id": "C0021853",
"pos": [
125,
135
],
"name": "intestinal"
} | {
"id": "C0021390",
"pos": [
29,
55
],
"name": "inflammatory bowel disease"
} | 11finding_site_of |
FMS-like tyrosine kinase 3-internal tandem duplication ( FLT3-ITD ) positive AML is associated with increased relapse risk and reduced overall survival ( OS ) compared to non-FLT3-mutated AML . | {
"id": "C1446409",
"pos": [
68,
76
],
"name": "positive"
} | {
"id": "C0023467",
"pos": [
77,
80
],
"name": "AML"
} | 0NA |
Non-transferrin bound iron ( NTBI ) may contribute to TRIM by promoting oxidative damage and pro-inflammatory cytokine release . | {
"id": "C0079189",
"pos": [
110,
118
],
"name": "cytokine"
} | {
"id": "C0302583",
"pos": [
22,
26
],
"name": "iron"
} | 0NA |
The acid-base equilibria of several amino acids , namely glycine , l-alanine , l-valine , l-leucine , l-phenylalanine , l-serine , l-methionine , and l-isoleucine , have been characterized in terms of microscopic protonation constants and tautomeric ratios . | {
"id": "C0002520",
"pos": [
36,
47
],
"name": "amino acids"
} | {
"id": "C0031453",
"pos": [
102,
117
],
"name": "l-phenylalanine"
} | 0NA |
The intestinal epithelium harbors large populations of activated and memory lymphocytes , yet these cells do not cause tissue damage in the steady state . | {
"id": "C0021853",
"pos": [
4,
14
],
"name": "intestinal"
} | {
"id": "C0014609",
"pos": [
15,
25
],
"name": "epithelium"
} | 0NA |
Thirty-eight patients with an advanced ovarian cancer ( FIGO stage III and IV ) were randomly allocated to treatment , either with melphalan ( M ) or a combination of adriamycin , 5-fluorouracil and cyclophosphamide ( CAF ) to determine the effect on survival . | {
"id": "C0025241",
"pos": [
131,
140
],
"name": "melphalan"
} | {
"id": "C0006644",
"pos": [
218,
221
],
"name": "CAF"
} | 0NA |
Occurrence of hemangioma in the small intestine and its presentation as acute intestinal obstruction are rare . | {
"id": "C0021852",
"pos": [
32,
47
],
"name": "small intestine"
} | {
"id": "C0018916",
"pos": [
14,
24
],
"name": "hemangioma"
} | 0NA |
When sodium citrate dissolved in dextrose was added to medium , there was considerable damage to both PPH and the C3A cell line . | {
"id": "C0010957",
"pos": [
87,
93
],
"name": "damage"
} | {
"id": "C0017725",
"pos": [
33,
41
],
"name": "dextrose"
} | 0NA |
The resection of the pedicle could be performed easily in an out-patient procedure 4 weeks after the operation . | {
"id": "C0015252",
"pos": [
4,
13
],
"name": "resection"
} | {
"id": "C0543467",
"pos": [
101,
110
],
"name": "operation"
} | 0NA |
Newcastle disease ( ND ) is a devastating worldwide disease of poultry characterized by increased respiration , circulatory disturbances , hemorrhagic enteritis , and nervous signs . | {
"id": "C0012634",
"pos": [
52,
59
],
"name": "disease"
} | {
"id": "C0035203",
"pos": [
98,
109
],
"name": "respiration"
} | 0NA |
Blood samples for hemagglutination-inhibition ( HI ) tests of serums and nasal secretions on swabs for viral isolation were collected from 20 feeder swine in each herd at the outset of surveillance . | {
"id": "C0178913",
"pos": [
0,
13
],
"name": "Blood samples"
} | {
"id": "C0022885",
"pos": [
53,
58
],
"name": "tests"
} | 0NA |
Eight consecutive eyes of seven patients ( five males and two females ; mean age , 64 ± 19 years ) treated by one surgeon ( KH ) were included in this study . | {
"id": "C0015392",
"pos": [
18,
22
],
"name": "eyes"
} | {
"id": "C0086582",
"pos": [
48,
53
],
"name": "males"
} | 0NA |
The operation time , blood loss , and postoperative hospital stay were 40－100 minutes , 5－30 ml , and 3－6 days , respectively . | {
"id": "C0543467",
"pos": [
4,
13
],
"name": "operation"
} | {
"id": "C0019080",
"pos": [
21,
31
],
"name": "blood loss"
} | 0NA |
The disease is characterized by bronchial hyperreactivity to physical , chemical , pharmacological , and/or immunological irritants . | {
"id": "C0031809",
"pos": [
61,
69
],
"name": "physical"
} | {
"id": "C0012634",
"pos": [
4,
11
],
"name": "disease"
} | 0NA |
Facial erythema , decrease in blood pressure , and elevation of histamine level were all accentuated by increasing the dose of mivacurium and by more rapid injection of the drug . | {
"id": "C0013227",
"pos": [
173,
177
],
"name": "drug"
} | {
"id": "C0021485",
"pos": [
156,
165
],
"name": "injection"
} | 10direct_substance_of |
Strassman metroplasty is a rare procedure in Sub-Saharan Africa and this case seeks to add to the body of knowledge on surgical management of Müllerian duct anomalies specifically bicornuate uterus in this region . | {
"id": "C0184661",
"pos": [
32,
41
],
"name": "procedure"
} | {
"id": "C0227230",
"pos": [
98,
102
],
"name": "body"
} | 0NA |
The drugs used in the case reports were limited to 6 antiretroviral agents ( efavirenz , nevirapine , lopinavir/ritonavir , nelfinavir , saquinavir , ritonavir ) . | {
"id": "C0292818",
"pos": [
150,
159
],
"name": "ritonavir"
} | {
"id": "C0939237",
"pos": [
102,
121
],
"name": "lopinavir/ritonavir"
} | 1active_ingredient_of |
MCMs are expressed in a higher proportion of NEN cells than Ki67 in slow-growing small intestinal lesions and correlate with survival . | {
"id": "C0221198",
"pos": [
98,
105
],
"name": "lesions"
} | {
"id": "C0021853",
"pos": [
87,
97
],
"name": "intestinal"
} | 0NA |
This study presents a small experience about a new strategy of myocardial protection during heart transplant . | {
"id": "C0027061",
"pos": [
63,
73
],
"name": "myocardial"
} | {
"id": "C0018823",
"pos": [
92,
108
],
"name": "heart transplant"
} | 0NA |
High ceiling diuretics allow a better control of fluid balance in dialysis patients with a minimum urine flow of 500 ml/day . | {
"id": "C0012798",
"pos": [
13,
22
],
"name": "diuretics"
} | {
"id": "C0014653",
"pos": [
55,
62
],
"name": "balance"
} | 0NA |
This ELISA could aid nonclinical evaluation of therapeutic interventions in T2DM . | {
"id": "C0087111",
"pos": [
47,
72
],
"name": "therapeutic interventions"
} | {
"id": "C0014441",
"pos": [
5,
10
],
"name": "ELISA"
} | 0NA |
Moreover , they bind and kill malignant B cells from peripheral blood samples obtained from patients with hairy cell leukemia , marginal zone lymphoma , and chronic lymphocytic leukemia . | {
"id": "C0242647",
"pos": [
128,
150
],
"name": "marginal zone lymphoma"
} | {
"id": "C0023443",
"pos": [
106,
125
],
"name": "hairy cell leukemia"
} | 0NA |
The purpose of this study was to examine the possible prevention by GH of the damage inflicted by dexamethasone ( Dex ) at sites of skeletal growth and ossification . | {
"id": "C0010957",
"pos": [
78,
84
],
"name": "damage"
} | {
"id": "C0011777",
"pos": [
98,
111
],
"name": "dexamethasone"
} | 0NA |
It was concluded that fentanyl was superior to nalbuphine in attenuating the pressor responses to intubation and surgery . | {
"id": "C0021925",
"pos": [
98,
108
],
"name": "intubation"
} | {
"id": "C0027348",
"pos": [
47,
57
],
"name": "nalbuphine"
} | 0NA |
SOC mineralization was greater and more sensitive to temperature changes in the farmland than in the tea plantations . | {
"id": "C0020517",
"pos": [
40,
49
],
"name": "sensitive"
} | {
"id": "C0005903",
"pos": [
53,
64
],
"name": "temperature"
} | 0NA |
Histamine-induced enhancement of the synthesis of PGI(2 ) , PGE(2 ) and IL-6 by LPS-primed HCAEC was completely blocked by an H1R antagonist . | {
"id": "C0028778",
"pos": [
112,
119
],
"name": "blocked"
} | {
"id": "C1627358",
"pos": [
18,
29
],
"name": "enhancement"
} | 0NA |
The tricyclic antidepressant , doxepin , has been reported to be a potent local anesthetic in rat sciatic nerve blockade . | {
"id": "C0002932",
"pos": [
80,
90
],
"name": "anesthetic"
} | {
"id": "C0013085",
"pos": [
31,
38
],
"name": "doxepin"
} | 0NA |
Studies with participants with renal disease , cancer , type 1 diabetes or heart failure or who are pregnant will be excluded . | {
"id": "C0006826",
"pos": [
47,
53
],
"name": "cancer"
} | {
"id": "C0018801",
"pos": [
75,
88
],
"name": "heart failure"
} | 0NA |
Nutritional therapy is important for the correction of nutritional deficiency , especially in cases where elective surgical treatment is required . | {
"id": "C0162429",
"pos": [
55,
77
],
"name": "nutritional deficiency"
} | {
"id": "C0543467",
"pos": [
115,
133
],
"name": "surgical treatment"
} | 0NA |
Prostate cancer ( PC ) is the most common cancer in men ; however , limited effect is obtained due to the therapy resistance . | {
"id": "C0006826",
"pos": [
42,
48
],
"name": "cancer"
} | {
"id": "C0376358",
"pos": [
0,
15
],
"name": "Prostate cancer"
} | 0NA |
Furthermore , the CsLCYb1 promoter activity was developmentally and tissue-specially regulated in transgenic Arabidopsis , and it was affected by multiple hormones and environmental cues in transgenic citrus callus under various treatments . | {
"id": "C0019932",
"pos": [
155,
163
],
"name": "hormones"
} | {
"id": "C0087111",
"pos": [
229,
239
],
"name": "treatments"
} | 0NA |
More policy attention is needed to strengthen established health-system responses to reduce breast and cervical cancer , especially in developing countries . | {
"id": "C0006141",
"pos": [
92,
98
],
"name": "breast"
} | {
"id": "C0007847",
"pos": [
103,
118
],
"name": "cervical cancer"
} | 0NA |
The incidence of abnormal findings in serum myocardial injury markers was positively correlated with HbCO concentration after CO poisoning . | {
"id": "C0205161",
"pos": [
17,
25
],
"name": "abnormal"
} | {
"id": "C0032343",
"pos": [
129,
138
],
"name": "poisoning"
} | 0NA |
Our results demonstrate that a pulseless limb is a poor predictor of arterial injury and should not be considered a hard sign of vascular injury in the combat population . | {
"id": "C0015385",
"pos": [
41,
45
],
"name": "limb"
} | {
"id": "C0340652",
"pos": [
69,
84
],
"name": "arterial injury"
} | 0NA |
Thus , allograft kidneys were infrequently infected with CMV ( 6 % ) , even in patients with viruria ( 24 % ) . | {
"id": "C0022646",
"pos": [
17,
24
],
"name": "kidneys"
} | {
"id": "C0040739",
"pos": [
7,
16
],
"name": "allograft"
} | 0NA |
Electrical stimulation of the vestibular system may be useful in the prevention of PONV . | {
"id": "C0199176",
"pos": [
69,
79
],
"name": "prevention"
} | {
"id": "C0520909",
"pos": [
83,
87
],
"name": "PONV"
} | 0NA |
CD4 + T cells are the only lymphocytes required for protection of mice against rotavirus shedding after mucosal immunization with chimeric VP6 ( MBP::VP6 ) and the adjuvant LT(R192 G ) . | {
"id": "C0026724",
"pos": [
104,
111
],
"name": "mucosal"
} | {
"id": "C0020971",
"pos": [
112,
124
],
"name": "immunization"
} | 0NA |
The use of imatinib , second and third generation ABL tyrosine kinase inhibitors ( TKI ) ( i.e. dasatinib , nilotinib , bosutinib and ponatinib ) made CML a clinically manageable and , in a small percentage of cases , a cured disease . | {
"id": "C2987417",
"pos": [
134,
143
],
"name": "ponatinib"
} | {
"id": "C0012634",
"pos": [
226,
233
],
"name": "disease"
} | 0NA |
The purpose of this study was to assess the ability of the HepG2 cell line to function as a bioassay for metal contamination in sediments , using metallothionein ( MT ) as a biomarker of exposure . | {
"id": "C0025552",
"pos": [
105,
110
],
"name": "metal"
} | {
"id": "C0274281",
"pos": [
187,
195
],
"name": "exposure"
} | 0NA |
Exogenous types associated with trauma , surgery or ulcer were mainly caused by Gram-positive bacteria of 37 strains , led by coagulase-negative staphylococci in 14 cases . | {
"id": "C0041582",
"pos": [
52,
57
],
"name": "ulcer"
} | {
"id": "C0080194",
"pos": [
109,
116
],
"name": "strains"
} | 0NA |
We further identify novel residues serine 145 , tyrosine 178 , and cysteine 189 on α-helices 6 , 7 , and 8 , respectively , within ζ-isoform as part of the GluN2C binding motif and independent of the canonical peptide binding groove . | {
"id": "C0010654",
"pos": [
67,
75
],
"name": "cysteine"
} | {
"id": "C0041485",
"pos": [
48,
56
],
"name": "tyrosine"
} | 0NA |
Transport of urea nd sodium from blood to CSF decreased to half of control values with increased Paw . | {
"id": "C0007806",
"pos": [
42,
45
],
"name": "CSF"
} | {
"id": "C0041942",
"pos": [
13,
17
],
"name": "urea"
} | 0NA |
Currently there are several screening methods : faecal occult blood tests , sigmoidoscopy , colonoscopy , barium enema and emerging methods like virtual colonoscopy and faecal DNA testing . | {
"id": "C0018941",
"pos": [
62,
73
],
"name": "blood tests"
} | {
"id": "C0009378",
"pos": [
92,
103
],
"name": "colonoscopy"
} | 0NA |
Lungs of lizards thus appeared to possess both CO2 receptors , which have functional characteristics similar to those in birds , and mechanoreceptors with properties similar to stretch receptors in mammals . | {
"id": "C0024109",
"pos": [
0,
5
],
"name": "Lungs"
} | {
"id": "C0034841",
"pos": [
177,
194
],
"name": "stretch receptors"
} | 0NA |
Predisposing factors to SIBO were more frequent in the VHD group , while warfarin interfering variables were not . | {
"id": "C0043031",
"pos": [
73,
81
],
"name": "warfarin"
} | {
"id": "C2959722",
"pos": [
24,
28
],
"name": "SIBO"
} | 0NA |
The pharmacokinetics and bacteriological efficacy of cefoperazone , cefuroxime , ceftriaxone , and moxalactam were evaluated in the experimental rabbit meningitis model of Haemophilus influenzae type b or Streptococcus pneumoniae infection . | {
"id": "C0007552",
"pos": [
53,
65
],
"name": "cefoperazone"
} | {
"id": "C0025289",
"pos": [
152,
162
],
"name": "meningitis"
} | 0NA |
The presence of digestive microflora influences these distributions : more histamine and mucosal mast cells are present in the small intestine of CV than in GF rats . | {
"id": "C0021852",
"pos": [
127,
142
],
"name": "small intestine"
} | {
"id": "C0026724",
"pos": [
89,
96
],
"name": "mucosal"
} | 0NA |
Genetic reprogramming emerging during or following brief episodes of ischemia that simulate angina , can be characterized as protective in nature . | {
"id": "C0022116",
"pos": [
69,
77
],
"name": "ischemia"
} | {
"id": "C0002962",
"pos": [
92,
98
],
"name": "angina"
} | 0NA |
The activity was more elevated in adenomas ( 149 ; 128 - 173 U ) than in cancers ( 103 ; 90 - 112 U ) . | {
"id": "C0006826",
"pos": [
73,
80
],
"name": "cancers"
} | {
"id": "C0001430",
"pos": [
34,
42
],
"name": "adenomas"
} | 0NA |
Gastrointestinal surgery can play a role in the treatment of pathologies frequently associated with a condition of neurological impairment such as gastro-oesophageal reflux disease ( antireflux procedure ) , feeding difficulties ( percutaneous endoscopic gastrostomy/jejunostomy ) and swallowing difficulties ( ligation of salivary gland ducts ) . | {
"id": "C0023690",
"pos": [
311,
319
],
"name": "ligation"
} | {
"id": "C0521654",
"pos": [
115,
138
],
"name": "neurological impairment"
} | 0NA |
We discuss the role of these cell surface components in pathogenic adhesion and in the formation of protected microcolonies at the surface of the infected ileal epithelium . | {
"id": "C0001511",
"pos": [
67,
75
],
"name": "adhesion"
} | {
"id": "C0020885",
"pos": [
155,
160
],
"name": "ileal"
} | 0NA |
This could favorably impact on mortality rates of cardiovascular disease , but untoward side effects of aspirin may be expected to increase as well . | {
"id": "C0004057",
"pos": [
104,
111
],
"name": "aspirin"
} | {
"id": "C0007222",
"pos": [
50,
72
],
"name": "cardiovascular disease"
} | 0NA |
Nitric oxide ( NO ) is an important molecule in the mammalian cardiovascular system and the elucidation of its biological role has led to the awarding of a Nobel prize in medicine . | {
"id": "C0013227",
"pos": [
171,
179
],
"name": "medicine"
} | {
"id": "C0028128",
"pos": [
0,
12
],
"name": "Nitric oxide"
} | 0NA |
Diabetes mellitus is the leading cause of cardiovascular morbidity and mortality . | {
"id": "C0007226",
"pos": [
42,
56
],
"name": "cardiovascular"
} | {
"id": "C0011849",
"pos": [
0,
17
],
"name": "Diabetes mellitus"
} | 0NA |
Both groups receive face-to-face communications with community pharmacists regarding angiotensin II receptor blockers ; the technology group receive additional AR-enhanced digital consumer medicine information throughout the use of their medications . | {
"id": "C0013227",
"pos": [
238,
249
],
"name": "medications"
} | {
"id": "C0521942",
"pos": [
85,
117
],
"name": "angiotensin II receptor blockers"
} | 0NA |
To investigate the in vivo whole blood metabolic clearance rates and sites of metabolism of prostaglandins A1 and E1 in man , constant infusions of the tritiated compounds were administered to normal subjects and to patients undergoing cardiac catheterization . | {
"id": "C0574032",
"pos": [
135,
144
],
"name": "infusions"
} | {
"id": "C0018795",
"pos": [
236,
259
],
"name": "cardiac catheterization"
} | 0NA |
S1P1 GPCRs are widely-expressed and physiologically critical in the cardiovascular and immune systems . | {
"id": "C0007226",
"pos": [
68,
82
],
"name": "cardiovascular"
} | {
"id": "C0020962",
"pos": [
87,
101
],
"name": "immune systems"
} | 0NA |
Anatomically accurate numerical models were built for all 3 cases , and numerical computations of electric field distribution in tumor and surrounding tissue were performed to determine the treatment outcome . | {
"id": "C0027651",
"pos": [
129,
134
],
"name": "tumor"
} | {
"id": "C0040300",
"pos": [
151,
157
],
"name": "tissue"
} | 0NA |
Five families had only breast cancer , four a combination of breast and ovarian cancer and the remaining 15 had also a variety of other cancers . | {
"id": "C0006141",
"pos": [
61,
67
],
"name": "breast"
} | {
"id": "C0006142",
"pos": [
23,
36
],
"name": "breast cancer"
} | 11finding_site_of |
Despite advances in surgical technique and medical therapy , > 5 % of patients require repeat revascularization within 1 year of CABG . | {
"id": "C0581603",
"pos": [
94,
111
],
"name": "revascularization"
} | {
"id": "C0010055",
"pos": [
129,
133
],
"name": "CABG"
} | 17method_of |
Results from two comparative studies and a meta-analysis of 53 randomised , placebo-controlled studies of oral triptans in > 24,000 patients , confirm that almotriptan 12.5 mg demonstrates comparable efficacy with sumatriptan 50 and 100 mg . | {
"id": "C0075632",
"pos": [
214,
225
],
"name": "sumatriptan"
} | {
"id": "C0914729",
"pos": [
156,
167
],
"name": "almotriptan"
} | 0NA |
Neck pain is a frequently reported complaint of the musculoskeletal system which can be disabling and costly to society . | {
"id": "C0026860",
"pos": [
52,
74
],
"name": "musculoskeletal system"
} | {
"id": "C0007859",
"pos": [
0,
9
],
"name": "Neck pain"
} | 0NA |
Increased levels of IL-6 appear to be associated with intracranial large-artery disease , suggesting a role for the inflammatory process in atherosclerosis of intracranial large arteries . | {
"id": "C0003842",
"pos": [
178,
186
],
"name": "arteries"
} | {
"id": "C0003850",
"pos": [
140,
155
],
"name": "atherosclerosis"
} | 11finding_site_of |
Geriatric patients who display both psychotic and OBS symptomatology were found to respond quite well to both drugs , regardless of their previous psychiatric history , but a somewhat more dramatic response was seen with thioridazine . | {
"id": "C0013227",
"pos": [
110,
115
],
"name": "drugs"
} | {
"id": "C0039943",
"pos": [
221,
233
],
"name": "thioridazine"
} | 0NA |
Posterior body reconstruction with a transpedicle body augmenter can maintain kyphosis correction and vertebral restoration , prevent implant failure , and lead to better clinical results . | {
"id": "C0549207",
"pos": [
102,
111
],
"name": "vertebral"
} | {
"id": "C0022821",
"pos": [
78,
86
],
"name": "kyphosis"
} | 0NA |
Innate mechanisms appear to be sufficient for the development of the excitatory connexions producing motion sensitivity and receptive field location on both retinas , but patterned visual experience is necessary for the ; fine-tuning ' which vetoes responses to stimuli with non-optimal configuration or binocular disparity . | {
"id": "C0035298",
"pos": [
157,
164
],
"name": "retinas"
} | {
"id": "C0020517",
"pos": [
108,
119
],
"name": "sensitivity"
} | 0NA |
Dental materials are common sources of artifacts during brain MRI studies . | {
"id": "C0006104",
"pos": [
56,
61
],
"name": "brain"
} | {
"id": "C0024485",
"pos": [
62,
65
],
"name": "MRI"
} | 0NA |
Once repaired the possible internal damage , an abdominal wall defect of high complexity may exist , whose reconstruction represents a surgical challenge . | {
"id": "C0543467",
"pos": [
135,
143
],
"name": "surgical"
} | {
"id": "C0836916",
"pos": [
48,
62
],
"name": "abdominal wall"
} | 0NA |
Pseudolymphoma of the breast is a rare benign disorder . | {
"id": "C0006141",
"pos": [
22,
28
],
"name": "breast"
} | {
"id": "C0221269",
"pos": [
0,
14
],
"name": "Pseudolymphoma"
} | 0NA |
Early focal depletion of proteoglycan was evident in the anulus fibrosus and reorganization of outer annular lamellas 3 to 6 months after the operation . | {
"id": "C0223087",
"pos": [
57,
72
],
"name": "anulus fibrosus"
} | {
"id": "C0543467",
"pos": [
142,
151
],
"name": "operation"
} | 0NA |
We report herein the case of an 11-year-old Thai girl with HIV infection , who developed severe abdominal pain and palpable purpura consistent with HSP , 3 months after planned antiretroviral treatment interruption ( PTI ) . | {
"id": "C0205082",
"pos": [
89,
95
],
"name": "severe"
} | {
"id": "C0000737",
"pos": [
96,
110
],
"name": "abdominal pain"
} | 0NA |
One week after the second injection , the lungs were removed and challenged intra-arterially with PAF or arachidonic acid . | {
"id": "C0024109",
"pos": [
42,
47
],
"name": "lungs"
} | {
"id": "C0021485",
"pos": [
26,
35
],
"name": "injection"
} | 0NA |
Caffeine ( 250 mg ) was administered orally to 15 healthy controls and eight patients with cirrhosis . | {
"id": "C0006644",
"pos": [
0,
8
],
"name": "Caffeine"
} | {
"id": "C0023890",
"pos": [
91,
100
],
"name": "cirrhosis"
} | 0NA |
Whole hemisphere autoradiography with [125I]nor-beta-CIT demonstrated high binding in the striatum , the thalamus and cortical regions of the human brain . | {
"id": "C0006104",
"pos": [
148,
153
],
"name": "brain"
} | {
"id": "C0010097",
"pos": [
90,
98
],
"name": "striatum"
} | 0NA |
Antimicrobial peptide/proteins are overexpressed in acne inversa lesions as compared with normal-appearing skin . | {
"id": "C0221198",
"pos": [
65,
72
],
"name": "lesions"
} | {
"id": "C0162836",
"pos": [
52,
64
],
"name": "acne inversa"
} | 0NA |
Modest weight loss and modest lower blood pressure each reduced the incidence of cardiovascular events , as expected . | {
"id": "C0007226",
"pos": [
81,
95
],
"name": "cardiovascular"
} | {
"id": "C0020649",
"pos": [
30,
50
],
"name": "lower blood pressure"
} | 11finding_site_of |
No dependence between the histological evidence of a chorioamnionitis and the time passed since PPRAM and between the bacterial contamination of the amniotic fluid and the presence of amnionitis could be established at all . | {
"id": "C0002638",
"pos": [
149,
163
],
"name": "amniotic fluid"
} | {
"id": "C0008495",
"pos": [
53,
69
],
"name": "chorioamnionitis"
} | 0NA |
An important barrier to formulating effective policies to address the rapid rise in U.S. fatal overdoses is that the specific drugs involved are frequently not identified on death certificates . | {
"id": "C0013227",
"pos": [
126,
131
],
"name": "drugs"
} | {
"id": "C0029944",
"pos": [
95,
104
],
"name": "overdoses"
} | 4causative_agent_of |
Expression of ABCG2 is normally absent or low in the pancreas , but high in human pancreatic cancer cells . | {
"id": "C0030274",
"pos": [
53,
61
],
"name": "pancreas"
} | {
"id": "C0235974",
"pos": [
82,
99
],
"name": "pancreatic cancer"
} | 11finding_site_of |
Marked degeneration of the LDM was noted , possibly caused by muscle ischemia-reperfusion damage after mobilization . | {
"id": "C0011164",
"pos": [
7,
19
],
"name": "degeneration"
} | {
"id": "C0026845",
"pos": [
62,
68
],
"name": "muscle"
} | 0NA |
On d 5 , fecal samples were collected , while ileal digesta were collected during two 10-h periods on d 6 and 7 . | {
"id": "C0020885",
"pos": [
46,
51
],
"name": "ileal"
} | {
"id": "C0025344",
"pos": [
91,
98
],
"name": "periods"
} | 0NA |
Phantom images with both geometries demonstrate the capability of the system to improve uniformity of film exposure and soft tissue contrast throughout the mediastinal , diaphragmatic , and retrocardiac areas . | {
"id": "C0025066",
"pos": [
156,
167
],
"name": "mediastinal"
} | {
"id": "C0225317",
"pos": [
120,
131
],
"name": "soft tissue"
} | 0NA |
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