instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'The exclusively nuclear location of HDH II/Ku antigen, its highly specific affinity for double-stranded DNA, its abundance and its newly demonstrated ability to unwind exclusively DNA duplexes, point to an additional, if still unclear, role for this molecule in DNA metabolism.', select the correct biomedical concept corresponding to 'hdh ii/ku'. Answer using one of the provided options. | <Options>: A: kub2 (homo sapiens) (aka x-ray repair cross complementing 5)
B: lethal (2) histolytic (drosophila melanogaster) (aka lethal (2) histolytic)
C: kub3 (homo sapiens) (aka atp23 metallopeptidase and atp synthase assembly factor homolog)
D: atp-dependent dna helicase 2 subunit ku70 (glycine max) (aka atp-dependent dna helicase 2 subunit ku70)
E: ku70/ku80 (drosophila melanogaster) (aka inverted repeat-binding protein)
F: None of the above. | A |
<Instruct>: Given the context 'A new cytokine (IK) down-regulating HLA class II: monoclonal antibodies, cloning and chromosome localization.
', select the correct biomedical concept corresponding to 'cytokine (ik)'. Answer using one of the provided options. | <Options>: A: ik cytokine (homo sapiens) (aka ik cytokine)
B: ik cytokine (xenopus tropicalis) (aka ik cytokine)
C: ik cytokine (mus musculus) (aka ik cytokine)
D: ik cytokine l homeolog (xenopus laevis) (aka ik cytokine l homeolog)
E: ik cytokine (rattus norvegicus) (aka ik cytokine)
F: None of the above. | A |
<Instruct>: Given the context 'We have purified a cytokine (IK factor, 19 kDa) secreted by the leukemic cell line K562 and several cancer cells, which inhibits HLA Class II antigen induction by IFN-gamma.', select the correct biomedical concept corresponding to 'ik factor'. Answer using one of the provided options. | <Options>: A: ikzf1 (homo sapiens) (aka ikaros family zinc finger 1)
B: ik cytokine (homo sapiens) (aka ik cytokine)
C: iklf (homo sapiens) (aka klf transcription factor 5)
D: ik-1 (xenopus tropicalis) (aka ikaros family zinc finger 1)
E: iklf (mus musculus) (aka kruppel-like transcription factor 5)
F: None of the above. | B |
<Instruct>: Given the context 'We have purified a cytokine (IK factor, 19 kDa) secreted by the leukemic cell line K562 and several cancer cells, which inhibits HLA Class II antigen induction by IFN-gamma.', select the correct biomedical concept corresponding to 'ifn-gamma'. Answer using one of the provided options. | <Options>: A: interferon gamma (homo sapiens) (aka interferon gamma)
B: interferon gamma (sus scrofa) (aka interferon gamma)
C: ifn-gamma (gallus gallus) (aka interferon)
D: gmf-gamma (homo sapiens) (aka glia maturation factor gamma)
E: interferon gamma (xenopus tropicalis) (aka interferon gamma)
F: None of the above. | A |
<Instruct>: Given the context 'We produced specific mAbs which antagonize the biological effect of IK in colon carcinoma Colo 205 cells induced to express HLA-DR molecules by IFN-gamma.', select the correct biomedical concept corresponding to 'ik'. Answer using one of the provided options. | <Options>: A: ik (mus musculus) (aka ik cytokine)
B: ik1 (xenopus laevis) (ikaros family zinc finger 1 l homeolog (xenopus laevis)) (aka ikaros family zinc finger 1 l homeolog)
C: ik (drosophila melanogaster) (aka i-kappab kinase beta)
D: ik (homo sapiens) (ik cytokine (homo sapiens)) (aka ik cytokine)
E: ikip (mus musculus) (aka ikbkb interacting protein)
F: None of the above. | D |
<Instruct>: Given the context 'We produced specific mAbs which antagonize the biological effect of IK in colon carcinoma Colo 205 cells induced to express HLA-DR molecules by IFN-gamma.', select the correct biomedical concept corresponding to 'ifn-gamma'. Answer using one of the provided options. | <Options>: A: interferon gamma (homo sapiens) (aka interferon gamma)
B: gmf-gamma (homo sapiens) (aka glia maturation factor gamma)
C: interferon gamma (sus scrofa) (aka interferon gamma)
D: cd3-gammaamma (homo sapiens) (aka cd3 gamma subunit of t-cell receptor complex)
E: interferon gamma (mus musculus) (aka interferon gamma)
F: None of the above. | A |
<Instruct>: Given the context 'We produced specific mAbs which antagonize the biological effect of IK in colon carcinoma Colo 205 cells induced to express HLA-DR molecules by IFN-gamma.', select the correct biomedical concept corresponding to 'ifn-gamma'. Answer using one of the provided options. | <Options>: A: gmf-gamma (homo sapiens) (aka glia maturation factor gamma)
B: ifn-gamma (gallus gallus) (aka interferon)
C: interferon gamma (oryctolagus cuniculus) (aka interferon gamma)
D: interferon gamma (mus musculus) (aka interferon gamma)
E: interleukin 36 gamma (homo sapiens) (aka interleukin 36 gamma)
F: None of the above. | F |
<Instruct>: Given the context 'Moreover, in Colo 205, HLA-DR can also be induced by the protein synthesis inhibitor Cycloheximide (0.1 micrograms ml-1); and addition of IK factor almost completely abolishes HLA class II expression.', select the correct biomedical concept corresponding to 'ik factor'. Answer using one of the provided options. | <Options>: A: iklf (homo sapiens) (aka klf transcription factor 5)
B: iklf (mus musculus) (aka kruppel-like transcription factor 5)
C: ik1 (xenopus laevis) (ikaros family zinc finger 1 l homeolog (xenopus laevis)) (aka ikaros family zinc finger 1 l homeolog)
D: ikzf1 (homo sapiens) (aka ikaros family zinc finger 1)
E: ik cytokine (homo sapiens) (aka ik cytokine)
F: None of the above. | E |
<Instruct>: Given the context 'IK gene localization shows that it maps on chromosome 2p15-p14.', select the correct biomedical concept corresponding to 'ik'. Answer using one of the provided options. | <Options>: A: ik1 (xenopus laevis) (ikaros family zinc finger 1 l homeolog (xenopus laevis)) (aka ikaros family zinc finger 1 l homeolog)
B: ik (drosophila melanogaster) (aka i-kappab kinase beta)
C: ik1 (mus musculus) (aka potassium intermediate/small conductance calcium-activated channel, subfamily n, member 4)
D: ik (bos taurus) (aka ik cytokine)
E: ik (homo sapiens) (ik cytokine (homo sapiens)) (aka ik cytokine)
F: None of the above. | E |
<Instruct>: Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: bmx (bos taurus) (aka bmx non-receptor tyrosine kinase)
B: bmx non-receptor tyrosine kinase (homo sapiens) (aka bmx non-receptor tyrosine kinase)
C: bmx (mus musculus) (aka bmx non-receptor tyrosine kinase)
D: mbx (homo sapiens) (aka diencephalon/mesencephalon homeobox 1)
E: bmh (xenopus tropicalis) (aka bleomycin hydrolase)
F: None of the above. | B |
<Instruct>: Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', select the correct biomedical concept corresponding to 'btk'. Answer using one of the provided options. | <Options>: A: blk proto-oncogene, src family tyrosine kinase (homo sapiens) (aka blk proto-oncogene, src family tyrosine kinase)
B: blk proto-oncogene, src family tyrosine kinase (xenopus tropicalis) (aka blk proto-oncogene, src family tyrosine kinase)
C: btkl (homo sapiens) (aka txk tyrosine kinase)
D: btk (homo sapiens) (aka bruton tyrosine kinase)
E: blk proto-oncogene, src family tyrosine kinase (bos taurus) (aka blk proto-oncogene, src family tyrosine kinase)
F: None of the above. | D |
<Instruct>: Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', select the correct biomedical concept corresponding to 'itk'. Answer using one of the provided options. | <Options>: A: ick (homo sapiens) (aka ciliogenesis associated kinase 1)
B: ibtk (homo sapiens) (aka inhibitor of bruton tyrosine kinase)
C: itk (xenopus tropicalis) (aka il2-inducible t cell kinase)
D: itk (danio rerio) (aka il2 inducible t cell kinase)
E: il2 inducible t cell kinase (homo sapiens) (aka il2 inducible t cell kinase)
F: None of the above. | E |
<Instruct>: Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', select the correct biomedical concept corresponding to 'tec'. Answer using one of the provided options. | <Options>: A: tecta (homo sapiens) (aka tectorin alpha)
B: teck (homo sapiens) (aka c-c motif chemokine ligand 25)
C: teck (xenopus tropicalis) (aka c-c motif chemokine ligand 25)
D: tec (xenopus laevis) (tec protein tyrosine kinase l homeolog (xenopus laevis)) (aka tec protein tyrosine kinase l homeolog)
E: tec protein tyrosine kinase (homo sapiens) (aka tec protein tyrosine kinase)
F: None of the above. | E |
<Instruct>: Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', select the correct biomedical concept corresponding to 'txk'. Answer using one of the provided options. | <Options>: A: txk (homo sapiens) (aka txk tyrosine kinase)
B: txk (sus scrofa) (aka txk tyrosine kinase)
C: txk (mus musculus) (aka txk tyrosine kinase)
D: txk (danio rerio) (aka txk tyrosine kinase)
E: txk (gallus gallus) (aka txk tyrosine kinase)
F: None of the above. | A |
<Instruct>: Given the context 'The Bmx sequence was identified and cloned during our search for novel tyrosine kinase genes expressed in human bone marrow cells.', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: mbx (homo sapiens) (aka diencephalon/mesencephalon homeobox 1)
B: bmnx (mus musculus) (aka body mass index)
C: bmx non-receptor tyrosine kinase (homo sapiens) (aka bmx non-receptor tyrosine kinase)
D: bmx (rattus norvegicus) (aka bmx non-receptor tyrosine kinase)
E: bmx non-receptor tyrosine kinase (mus musculus) (aka bmx non-receptor tyrosine kinase)
F: None of the above. | C |
<Instruct>: Given the context 'Bmx cDNA comprises a long open reading frame of 675 amino acids, containing one SH3, one SH2 and one tyrosine kinase domain, which are about 70% identical with Btk, Itk and Tec and somewhat less with Txk tyrosine kinase sequences.', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: bmx (gallus gallus) (aka bmx non-receptor tyrosine kinase)
B: bmh (xenopus tropicalis) (aka bleomycin hydrolase)
C: bmnx (mus musculus) (aka body mass index)
D: bmx non-receptor tyrosine kinase (homo sapiens) (aka bmx non-receptor tyrosine kinase)
E: bmx (bos taurus) (aka bmx non-receptor tyrosine kinase)
F: None of the above. | D |
<Instruct>: Given the context 'Bmx cDNA comprises a long open reading frame of 675 amino acids, containing one SH3, one SH2 and one tyrosine kinase domain, which are about 70% identical with Btk, Itk and Tec and somewhat less with Txk tyrosine kinase sequences.', select the correct biomedical concept corresponding to 'btk'. Answer using one of the provided options. | <Options>: A: btkl (homo sapiens) (aka txk tyrosine kinase)
B: blk proto-oncogene, src family tyrosine kinase (bos taurus) (aka blk proto-oncogene, src family tyrosine kinase)
C: btk (bos taurus) (aka bruton tyrosine kinase)
D: bruton tyrosine kinase (homo sapiens) (aka bruton tyrosine kinase)
E: blk proto-oncogene, src family tyrosine kinase (xenopus tropicalis) (aka blk proto-oncogene, src family tyrosine kinase)
F: None of the above. | D |
<Instruct>: Given the context 'Bmx cDNA comprises a long open reading frame of 675 amino acids, containing one SH3, one SH2 and one tyrosine kinase domain, which are about 70% identical with Btk, Itk and Tec and somewhat less with Txk tyrosine kinase sequences.', select the correct biomedical concept corresponding to 'btk'. Answer using one of the provided options. | <Options>: A: blk (homo sapiens) (aka blk proto-oncogene, src family tyrosine kinase)
B: bruton tyrosine kinase (xenopus tropicalis) (aka bruton tyrosine kinase)
C: btk (bos taurus) (aka bruton tyrosine kinase)
D: btkl (homo sapiens) (aka txk tyrosine kinase)
E: blk proto-oncogene, src family tyrosine kinase (xenopus tropicalis) (aka blk proto-oncogene, src family tyrosine kinase)
F: None of the above. | F |
<Instruct>: Given the context 'Bmx cDNA comprises a long open reading frame of 675 amino acids, containing one SH3, one SH2 and one tyrosine kinase domain, which are about 70% identical with Btk, Itk and Tec and somewhat less with Txk tyrosine kinase sequences.', select the correct biomedical concept corresponding to 'itk'. Answer using one of the provided options. | <Options>: A: ibtk (homo sapiens) (aka inhibitor of bruton tyrosine kinase)
B: integrin linked kinase (homo sapiens) (aka integrin linked kinase)
C: ick (homo sapiens) (aka ciliogenesis associated kinase 1)
D: itk (gallus gallus) (aka il2 inducible t-cell kinase)
E: itk (homo sapiens) (aka il2 inducible t cell kinase)
F: None of the above. | E |
<Instruct>: Given the context 'Bmx cDNA comprises a long open reading frame of 675 amino acids, containing one SH3, one SH2 and one tyrosine kinase domain, which are about 70% identical with Btk, Itk and Tec and somewhat less with Txk tyrosine kinase sequences.', select the correct biomedical concept corresponding to 'tec'. Answer using one of the provided options. | <Options>: A: tec (sus scrofa) (aka tec protein tyrosine kinase)
B: tec (homo sapiens) (transient erythroblastopenia of childhood (homo sapiens)) (aka transient erythroblastopenia of childhood)
C: tec (xenopus laevis) (tec protein tyrosine kinase l homeolog (xenopus laevis)) (aka tec protein tyrosine kinase l homeolog)
D: tecta (homo sapiens) (aka tectorin alpha)
E: tec protein tyrosine kinase (homo sapiens) (aka tec protein tyrosine kinase)
F: None of the above. | E |
<Instruct>: Given the context 'Bmx cDNA comprises a long open reading frame of 675 amino acids, containing one SH3, one SH2 and one tyrosine kinase domain, which are about 70% identical with Btk, Itk and Tec and somewhat less with Txk tyrosine kinase sequences.', select the correct biomedical concept corresponding to 'txk'. Answer using one of the provided options. | <Options>: A: txk tyrosine kinase (sus scrofa) (aka txk tyrosine kinase)
B: txk (mus musculus) (aka txk tyrosine kinase)
C: txk (bos taurus) (aka txk tyrosine kinase)
D: txk (gallus gallus) (aka txk tyrosine kinase)
E: txk tyrosine kinase (homo sapiens) (aka txk tyrosine kinase)
F: None of the above. | E |
<Instruct>: Given the context 'The 2.7 kb Bmx mRNA was expressed in endothelial cells and several human tissues by Northern blotting and an 80 kD Bmx polypeptide was detected in human endothelial cells.', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: bmh (xenopus tropicalis) (aka bleomycin hydrolase)
B: mbx (homo sapiens) (aka diencephalon/mesencephalon homeobox 1)
C: bmnx (mus musculus) (aka body mass index)
D: bmx non-receptor tyrosine kinase (homo sapiens) (aka bmx non-receptor tyrosine kinase)
E: bmx (gallus gallus) (aka bmx non-receptor tyrosine kinase)
F: None of the above. | D |
<Instruct>: Given the context 'The 2.7 kb Bmx mRNA was expressed in endothelial cells and several human tissues by Northern blotting and an 80 kD Bmx polypeptide was detected in human endothelial cells.', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: mbx (homo sapiens) (aka diencephalon/mesencephalon homeobox 1)
B: bmx (bos taurus) (aka bmx non-receptor tyrosine kinase)
C: bmx (rattus norvegicus) (aka bmx non-receptor tyrosine kinase)
D: bmh (xenopus tropicalis) (aka bleomycin hydrolase)
E: bmx (homo sapiens) (aka bmx non-receptor tyrosine kinase)
F: None of the above. | E |
<Instruct>: Given the context 'Immunoprecipitates of COS cells transfected with a Bmx expression vector and NIH3T3 cells expressing a Bmx retrovirus contained a tyrosyl phosphorylated Bmx polypeptide of similar molecular weight.', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: mbx (homo sapiens) (aka diencephalon/mesencephalon homeobox 1)
B: bmnx (mus musculus) (aka body mass index)
C: bmx non-receptor tyrosine kinase (homo sapiens) (aka bmx non-receptor tyrosine kinase)
D: bmx (rattus norvegicus) (aka bmx non-receptor tyrosine kinase)
E: bmx (gallus gallus) (aka bmx non-receptor tyrosine kinase)
F: None of the above. | C |
<Instruct>: Given the context 'Immunoprecipitates of COS cells transfected with a Bmx expression vector and NIH3T3 cells expressing a Bmx retrovirus contained a tyrosyl phosphorylated Bmx polypeptide of similar molecular weight.', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: mbx (homo sapiens) (aka diencephalon/mesencephalon homeobox 1)
B: bmx (gallus gallus) (aka bmx non-receptor tyrosine kinase)
C: bmx (rattus norvegicus) (aka bmx non-receptor tyrosine kinase)
D: bmnx (mus musculus) (aka body mass index)
E: bmx non-receptor tyrosine kinase (homo sapiens) (aka bmx non-receptor tyrosine kinase)
F: None of the above. | E |
<Instruct>: Given the context 'Immunoprecipitates of COS cells transfected with a Bmx expression vector and NIH3T3 cells expressing a Bmx retrovirus contained a tyrosyl phosphorylated Bmx polypeptide of similar molecular weight.', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: mbx (homo sapiens) (aka diencephalon/mesencephalon homeobox 1)
B: bmx (rattus norvegicus) (aka bmx non-receptor tyrosine kinase)
C: bmx (gallus gallus) (aka bmx non-receptor tyrosine kinase)
D: bmx (mus musculus) (aka bmx non-receptor tyrosine kinase)
E: bmx non-receptor tyrosine kinase (homo sapiens) (aka bmx non-receptor tyrosine kinase)
F: None of the above. | E |
<Instruct>: Given the context 'The BMX gene was located in chromosomal band Xp22.2 between the DXS197 and DXS207 loci.', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: bmx (rattus norvegicus) (aka bmx non-receptor tyrosine kinase)
B: bmx (gallus gallus) (aka bmx non-receptor tyrosine kinase)
C: bmnx (mus musculus) (aka body mass index)
D: bmx (homo sapiens) (aka bmx non-receptor tyrosine kinase)
E: bmx (mus musculus) (aka bmx non-receptor tyrosine kinase)
F: None of the above. | D |
<Instruct>: Given the context 'Interestingly, chromosome X also contains the closest relative of BMX, the BTK gene, implicated in X-linked agammaglobulinemia.', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: bmx non-receptor tyrosine kinase (homo sapiens) (aka bmx non-receptor tyrosine kinase)
B: bmh (xenopus tropicalis) (aka bleomycin hydrolase)
C: bmx (rattus norvegicus) (aka bmx non-receptor tyrosine kinase)
D: bmx (mus musculus) (aka bmx non-receptor tyrosine kinase)
E: bmx (gallus gallus) (aka bmx non-receptor tyrosine kinase)
F: None of the above. | A |
<Instruct>: Given the context 'Interestingly, chromosome X also contains the closest relative of BMX, the BTK gene, implicated in X-linked agammaglobulinemia.', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: bmx (mus musculus) (aka bmx non-receptor tyrosine kinase)
B: bmx (bos taurus) (aka bmx non-receptor tyrosine kinase)
C: bmx (rattus norvegicus) (aka bmx non-receptor tyrosine kinase)
D: bmnx (mus musculus) (aka body mass index)
E: mbx (homo sapiens) (aka diencephalon/mesencephalon homeobox 1)
F: None of the above. | F |
<Instruct>: Given the context 'Interestingly, chromosome X also contains the closest relative of BMX, the BTK gene, implicated in X-linked agammaglobulinemia.', select the correct biomedical concept corresponding to 'btk'. Answer using one of the provided options. | <Options>: A: bruton tyrosine kinase (xenopus tropicalis) (aka bruton tyrosine kinase)
B: btk (homo sapiens) (aka bruton tyrosine kinase)
C: blk proto-oncogene, src family tyrosine kinase (homo sapiens) (aka blk proto-oncogene, src family tyrosine kinase)
D: btkl (homo sapiens) (aka txk tyrosine kinase)
E: blk proto-oncogene, src family tyrosine kinase (xenopus tropicalis) (aka blk proto-oncogene, src family tyrosine kinase)
F: None of the above. | B |
<Instruct>: Given the context 'The BMX gene thus encodes a novel nonreceptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells.', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: bmx non-receptor tyrosine kinase (homo sapiens) (aka bmx non-receptor tyrosine kinase)
B: bmx (bos taurus) (aka bmx non-receptor tyrosine kinase)
C: bmx (gallus gallus) (aka bmx non-receptor tyrosine kinase)
D: bmh (xenopus tropicalis) (aka bleomycin hydrolase)
E: bmnx (mus musculus) (aka body mass index)
F: None of the above. | A |
<Instruct>: Given the context 'Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours.
', select the correct biomedical concept corresponding to 'brk'. Answer using one of the provided options. | <Options>: A: brpk (homo sapiens) (aka pten induced kinase 1)
B: brk-3 (homo sapiens) (aka bone morphogenetic protein receptor type 2)
C: brk (drosophila melanogaster) (aka brinker)
D: brk1 (homo sapiens) (aka brick1 subunit of scar/wave actin nucleating complex)
E: brk (homo sapiens) (aka protein tyrosine kinase 6)
F: None of the above. | E |
<Instruct>: Given the context 'Using a polymerase chain reaction based differential screening approach, we have isolated and characterised a cDNA from a human metastatic breast tumour representing a novel protein tyrosine kinase (brk).', select the correct biomedical concept corresponding to 'brk'. Answer using one of the provided options. | <Options>: A: brk1 (homo sapiens) (aka brick1 subunit of scar/wave actin nucleating complex)
B: brk-3 (homo sapiens) (aka bone morphogenetic protein receptor type 2)
C: br serine/threonine kinase 1 (homo sapiens) (aka br serine/threonine kinase 1)
D: brpk (homo sapiens) (aka pten induced kinase 1)
E: brk (homo sapiens) (aka protein tyrosine kinase 6)
F: None of the above. | E |
<Instruct>: Given the context 'Sequencing of brk cDNAs isolated from T-47D and MCF-7 human breast tumour cell lines indicate that they encode a protein with the features of a novel nonreceptor tyrosine kinase, including amino terminal SH3 and SH2 domains.', select the correct biomedical concept corresponding to 'brk'. Answer using one of the provided options. | <Options>: A: brk-1 (gallus gallus) (aka bone morphogenetic protein receptor type 1a)
B: brk (homo sapiens) (aka protein tyrosine kinase 6)
C: brpk (homo sapiens) (aka pten induced kinase 1)
D: brk1 (bos taurus) (aka brick1 subunit of scar/wave actin nucleating complex)
E: br serine/threonine kinase 1 (homo sapiens) (aka br serine/threonine kinase 1)
F: None of the above. | B |
<Instruct>: Given the context 'When synthesised in recombinant baculovirus and bacterial expression systems, brk protein products are capable of autophosphorylation on tyrosine residues.', select the correct biomedical concept corresponding to 'brk'. Answer using one of the provided options. | <Options>: A: br serine/threonine kinase 1 (homo sapiens) (aka br serine/threonine kinase 1)
B: brks (homo sapiens) (aka fkbp prolyl isomerase 10)
C: brk (homo sapiens) (aka protein tyrosine kinase 6)
D: brk (drosophila melanogaster) (aka brinker)
E: brk-3 (homo sapiens) (aka bone morphogenetic protein receptor type 2)
F: None of the above. | C |
<Instruct>: Given the context 'Initial expression studies have detected low levels of brk transcripts in some human breast tumours and breast tumour cell lines, but not in normal breast tissue.', select the correct biomedical concept corresponding to 'brk'. Answer using one of the provided options. | <Options>: A: brks (homo sapiens) (aka fkbp prolyl isomerase 10)
B: brk (homo sapiens) (aka protein tyrosine kinase 6)
C: brk-1 (gallus gallus) (aka bone morphogenetic protein receptor type 1a)
D: brk1 (bos taurus) (aka brick1 subunit of scar/wave actin nucleating complex)
E: brk-3 (homo sapiens) (aka bone morphogenetic protein receptor type 2)
F: None of the above. | B |
<Instruct>: Given the context 'Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes.
', select the correct biomedical concept corresponding to 'pc4'. Answer using one of the provided options. | <Options>: A: proprotein convertase subtilisin/kexin type 4 (homo sapiens) (aka proprotein convertase subtilisin/kexin type 4)
B: pc4-like (drosophila melanogaster) (aka single stranded-binding protein c31a)
C: pc4 (homo sapiens) (sub1 regulator of transcription (homo sapiens)) (aka sub1 regulator of transcription)
D: prostate cancer, hereditary, 4 (homo sapiens) (aka prostate cancer, hereditary, 4)
E: pch4 (homo sapiens) (aka trna splicing endonuclease subunit 54)
F: None of the above. | C |
<Instruct>: Given the context 'A novel positive cofactor (PC4) purified from the human USA fraction effected a marked enhancement (up to 85-fold) of GAL4-AH-dependent transcription in conjunction with TFIID and other general factors.', select the correct biomedical concept corresponding to 'pc4'. Answer using one of the provided options. | <Options>: A: pc4 (mus musculus) (sub1 homolog, transcriptional regulator (mus musculus)) (aka sub1 homolog, transcriptional regulator)
B: pch4 (homo sapiens) (aka trna splicing endonuclease subunit 54)
C: pc4 (homo sapiens) (proprotein convertase subtilisin/kexin type 4 (homo sapiens)) (aka proprotein convertase subtilisin/kexin type 4)
D: pc4 (homo sapiens) (sub1 regulator of transcription (homo sapiens)) (aka sub1 regulator of transcription)
E: pc4 (mus musculus) (proprotein convertase subtilisin/kexin type 4 (mus musculus)) (aka proprotein convertase subtilisin/kexin type 4)
F: None of the above. | D |
<Instruct>: Given the context 'A novel positive cofactor (PC4) purified from the human USA fraction effected a marked enhancement (up to 85-fold) of GAL4-AH-dependent transcription in conjunction with TFIID and other general factors.', select the correct biomedical concept corresponding to 'gal4'. Answer using one of the provided options. | <Options>: A: gal4 (xenopus tropicalis) (aka lectin, galactoside-binding, soluble, 4, gene 2)
B: transcription activator glk1-like (glycine max) (aka transcription activator glk1-like)
C: gal4 (xenopus laevis) (lectin, galactoside-binding, soluble, 4, gene 2, s homeolog (xenopus laevis)) (aka lectin, galactoside-binding, soluble, 4, gene 2, s homeolog)
D: kruppel homolog 1 (drosophila melanogaster) (aka kruppel homolog 1)
E: gal4 (homo sapiens) (aka galectin 4)
F: None of the above. | E |
<Instruct>: Given the context 'A novel positive cofactor (PC4) purified from the human USA fraction effected a marked enhancement (up to 85-fold) of GAL4-AH-dependent transcription in conjunction with TFIID and other general factors.', select the correct biomedical concept corresponding to 'gal4'. Answer using one of the provided options. | <Options>: A: gtf-1 (drosophila melanogaster) (aka germ line transcription factor 1)
B: gal4 (xenopus laevis) (lectin, galactoside-binding, soluble, 4, gene 2, s homeolog (xenopus laevis)) (aka lectin, galactoside-binding, soluble, 4, gene 2, s homeolog)
C: kruppel homolog 1 (drosophila melanogaster) (aka kruppel homolog 1)
D: gal4 (xenopus tropicalis) (aka lectin, galactoside-binding, soluble, 4, gene 2)
E: chromatin modification-related protein eaf-1 (glycine max) (aka chromatin modification-related protein eaf-1)
F: None of the above. | F |
<Instruct>: Given the context 'Isolation of a corresponding cDNA identified PC4 as a 127 residue single-stranded DNA-binding protein with serine-rich regions near the N-terminus.', select the correct biomedical concept corresponding to 'pc4'. Answer using one of the provided options. | <Options>: A: prostate cancer, hereditary, 4 (homo sapiens) (aka prostate cancer, hereditary, 4)
B: pc4-like (drosophila melanogaster) (aka single stranded-binding protein c31a)
C: pc4 (homo sapiens) (sub1 regulator of transcription (homo sapiens)) (aka sub1 regulator of transcription)
D: pc4 (mus musculus) (sub1 homolog, transcriptional regulator (mus musculus)) (aka sub1 homolog, transcriptional regulator)
E: pc4 (mus musculus) (proprotein convertase subtilisin/kexin type 4 (mus musculus)) (aka proprotein convertase subtilisin/kexin type 4)
F: None of the above. | C |
<Instruct>: Given the context 'Recombinant PC4 was functionally equivalent to native PC4, and both proteins markedly enhanced activation by diverse activation domains fused to the DNA-binding domain of GAL4.', select the correct biomedical concept corresponding to 'pc4'. Answer using one of the provided options. | <Options>: A: pc4-like (drosophila melanogaster) (aka single stranded-binding protein c31a)
B: prostate cancer, hereditary, 4 (homo sapiens) (aka prostate cancer, hereditary, 4)
C: pc4 (homo sapiens) (sub1 regulator of transcription (homo sapiens)) (aka sub1 regulator of transcription)
D: pc4 (mus musculus) (proprotein convertase subtilisin/kexin type 4 (mus musculus)) (aka proprotein convertase subtilisin/kexin type 4)
E: pc4 (mus musculus) (sub1 homolog, transcriptional regulator (mus musculus)) (aka sub1 homolog, transcriptional regulator)
F: None of the above. | C |
<Instruct>: Given the context 'Recombinant PC4 was functionally equivalent to native PC4, and both proteins markedly enhanced activation by diverse activation domains fused to the DNA-binding domain of GAL4.', select the correct biomedical concept corresponding to 'pc4'. Answer using one of the provided options. | <Options>: A: pcsk4 (homo sapiens) (aka proprotein convertase subtilisin/kexin type 4)
B: pc4 (homo sapiens) (sub1 regulator of transcription (homo sapiens)) (aka sub1 regulator of transcription)
C: pc4 (xenopus laevis) (aka proprotein convertase subtilisin/kexin type 4 l homeolog)
D: pc4 (mus musculus) (proprotein convertase subtilisin/kexin type 4 (mus musculus)) (aka proprotein convertase subtilisin/kexin type 4)
E: prostate cancer, hereditary, 4 (homo sapiens) (aka prostate cancer, hereditary, 4)
F: None of the above. | B |
<Instruct>: Given the context 'Recombinant PC4 was functionally equivalent to native PC4, and both proteins markedly enhanced activation by diverse activation domains fused to the DNA-binding domain of GAL4.', select the correct biomedical concept corresponding to 'gal4'. Answer using one of the provided options. | <Options>: A: gtf-1 (drosophila melanogaster) (aka germ line transcription factor 1)
B: gal4 (candida albicans sc5314) (aka galactose-responsive transcription factor)
C: gal4 (homo sapiens) (aka galectin 4)
D: gal4 (saccharomyces cerevisiae s288c) (aka galactose-responsive transcription factor gal4)
E: kruppel homolog 1 (drosophila melanogaster) (aka kruppel homolog 1)
F: None of the above. | C |
<Instruct>: Given the context 'Recombinant PC4 interacted independently both with free or DNA-bound VP16 activation domains and with free or DNA-bound TFIIA-TBP complexes (but not with TBP alone).', select the correct biomedical concept corresponding to 'pc4'. Answer using one of the provided options. | <Options>: A: pc4 (homo sapiens) (sub1 regulator of transcription (homo sapiens)) (aka sub1 regulator of transcription)
B: pch4 (homo sapiens) (aka trna splicing endonuclease subunit 54)
C: pc4 (xenopus laevis) (aka proprotein convertase subtilisin/kexin type 4 l homeolog)
D: pc4-like (drosophila melanogaster) (aka single stranded-binding protein c31a)
E: pc4 (mus musculus) (sub1 homolog, transcriptional regulator (mus musculus)) (aka sub1 homolog, transcriptional regulator)
F: None of the above. | A |
<Instruct>: Given the context 'Recombinant PC4 interacted independently both with free or DNA-bound VP16 activation domains and with free or DNA-bound TFIIA-TBP complexes (but not with TBP alone).', select the correct biomedical concept corresponding to 'tbp'. Answer using one of the provided options. | <Options>: A: tata-box binding protein (bos taurus) (aka tata-box binding protein)
B: tbp-b (xenopus tropicalis) (aka tata-box binding protein)
C: tbp protein-like pseudogene (bos taurus) (aka tbp protein-like pseudogene)
D: tata-box binding protein like 1 (xenopus tropicalis) (aka tata-box binding protein like 1)
E: tata-box binding protein (homo sapiens) (aka tata-box binding protein)
F: None of the above. | F |
<Instruct>: Given the context 'These results indicate that PC4 is a general coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery.', select the correct biomedical concept corresponding to 'pc4'. Answer using one of the provided options. | <Options>: A: prostate cancer, hereditary, 4 (homo sapiens) (aka prostate cancer, hereditary, 4)
B: pc4-like (drosophila melanogaster) (aka single stranded-binding protein c31a)
C: pc4 (xenopus laevis) (aka proprotein convertase subtilisin/kexin type 4 l homeolog)
D: pch4 (homo sapiens) (aka trna splicing endonuclease subunit 54)
E: pc4 (homo sapiens) (sub1 regulator of transcription (homo sapiens)) (aka sub1 regulator of transcription)
F: None of the above. | E |
<Instruct>: Given the context 'Molecular cloning, sequencing, and functional expression of a cDNA encoding human coproporphyrinogen oxidase.
Coproporphyrinogen oxidase (EC 1.3.3.3) catalyzes the sixth step in the heme biosynthetic pathway, the oxidation of coproporphyrinogen III to protoporphyrinogen IX.', select the correct biomedical concept corresponding to 'coproporphyrinogen oxidase'. Answer using one of the provided options. | <Options>: A: coproporphyrinogen oxidase (saccharomyces cerevisiae s288c) (aka coproporphyrinogen oxidase)
B: cpo (homo sapiens) (coproporphyrinogen oxidase (homo sapiens)) (aka coproporphyrinogen oxidase)
C: protoporphyrinogen oxidase (homo sapiens) (aka protoporphyrinogen oxidase)
D: coproporphyrinogen oxidase (drosophila melanogaster) (aka coproporphyrinogen oxidase)
E: coproporphyrinogen-iii oxidase-like (glycine max) (aka coproporphyrinogen-iii oxidase-like)
F: None of the above. | B |
<Instruct>: Given the context 'Molecular cloning, sequencing, and functional expression of a cDNA encoding human coproporphyrinogen oxidase.
Coproporphyrinogen oxidase (EC 1.3.3.3) catalyzes the sixth step in the heme biosynthetic pathway, the oxidation of coproporphyrinogen III to protoporphyrinogen IX.', select the correct biomedical concept corresponding to 'coproporphyrinogen oxidase'. Answer using one of the provided options. | <Options>: A: coproporphyrinogen oxidase (drosophila melanogaster) (aka coproporphyrinogen oxidase)
B: coproporphyrinogen oxidase (glycine max) (aka coproporphyrinogen oxidase)
C: cox (homo sapiens) (coproporphyrinogen oxidase (homo sapiens)) (aka coproporphyrinogen oxidase)
D: coproporphyrinogen oxidase (danio rerio) (aka coproporphyrinogen oxidase)
E: coproporphyrinogen-iii oxidase-like (glycine max) (aka coproporphyrinogen-iii oxidase-like)
F: None of the above. | C |
<Instruct>: Given the context 'The sequence of the cDNA and predicted amino acid sequence of the human coproporphyrinogen oxidase are presented.', select the correct biomedical concept corresponding to 'coproporphyrinogen oxidase'. Answer using one of the provided options. | <Options>: A: coproporphyrinogen oxidase (danio rerio) (aka coproporphyrinogen oxidase)
B: coproporphyrinogen oxidase (homo sapiens) (aka coproporphyrinogen oxidase)
C: coproporphyrinogen oxidase (drosophila melanogaster) (aka coproporphyrinogen oxidase)
D: coproporphyrinogen oxidase (glycine max) (aka coproporphyrinogen oxidase)
E: protoporphyrinogen oxidase (homo sapiens) (aka protoporphyrinogen oxidase)
F: None of the above. | B |
<Instruct>: Given the context 'The sequence of the cDNA and predicted amino acid sequence of the human coproporphyrinogen oxidase are presented.', select the correct biomedical concept corresponding to 'coproporphyrinogen oxidase'. Answer using one of the provided options. | <Options>: A: coproporphyrinogen oxidase (saccharomyces cerevisiae s288c) (aka coproporphyrinogen oxidase)
B: coproporphyrinogen oxidase (drosophila melanogaster) (aka coproporphyrinogen oxidase)
C: protoporphyrinogen oxidase (homo sapiens) (aka protoporphyrinogen oxidase)
D: coproporphyrinogen-iii oxidase-like (glycine max) (aka coproporphyrinogen-iii oxidase-like)
E: coproporphyrinogen oxidase (glycine max) (aka coproporphyrinogen oxidase)
F: None of the above. | F |
<Instruct>: Given the context 'The human protein sequence contains a region completely homologous to that we obtained by sequencing an 11-amino acid peptide fragment from purified murine liver coproporphyrinogen oxidase.', select the correct biomedical concept corresponding to 'coproporphyrinogen oxidase'. Answer using one of the provided options. | <Options>: A: protoporphyrinogen oxidase (homo sapiens) (aka protoporphyrinogen oxidase)
B: coproporphyrinogen oxidase (glycine max) (aka coproporphyrinogen oxidase)
C: coproporphyrinogen oxidase (danio rerio) (aka coproporphyrinogen oxidase)
D: cpx (homo sapiens) (coproporphyrinogen oxidase (homo sapiens)) (aka coproporphyrinogen oxidase)
E: coproporphyrinogen oxidase (saccharomyces cerevisiae s288c) (aka coproporphyrinogen oxidase)
F: None of the above. | D |
<Instruct>: Given the context 'Results of Southern blotting were consistent with the presence of a single human coproporphyrinogen oxidase gene, and Northern blotting demonstrated one transcript of similar size in erythroid and nonerythroid cell lines.', select the correct biomedical concept corresponding to 'coproporphyrinogen oxidase'. Answer using one of the provided options. | <Options>: A: coproporphyrinogen-iii oxidase-like (glycine max) (aka coproporphyrinogen-iii oxidase-like)
B: cpx (homo sapiens) (coproporphyrinogen oxidase (homo sapiens)) (aka coproporphyrinogen oxidase)
C: protoporphyrinogen oxidase (homo sapiens) (aka protoporphyrinogen oxidase)
D: coproporphyrinogen oxidase (drosophila melanogaster) (aka coproporphyrinogen oxidase)
E: coproporphyrinogen oxidase (danio rerio) (aka coproporphyrinogen oxidase)
F: None of the above. | B |
<Instruct>: Given the context 'Expression of the cDNA coding for the putative mature human coproporphyrinogen oxidase in Escherichia coli resulted in a 17-fold increase in coproporphyrinogen activity over endogenous activity.', select the correct biomedical concept corresponding to 'coproporphyrinogen oxidase'. Answer using one of the provided options. | <Options>: A: coproporphyrinogen oxidase (danio rerio) (aka coproporphyrinogen oxidase)
B: protoporphyrinogen oxidase (homo sapiens) (aka protoporphyrinogen oxidase)
C: coproporphyrinogen oxidase (saccharomyces cerevisiae s288c) (aka coproporphyrinogen oxidase)
D: coproporphyrinogen oxidase (drosophila melanogaster) (aka coproporphyrinogen oxidase)
E: cpx (homo sapiens) (coproporphyrinogen oxidase (homo sapiens)) (aka coproporphyrinogen oxidase)
F: None of the above. | E |
<Instruct>: Given the context 'Molecular cloning and characterization of a novel human sperm antigen (HE2) specifically expressed in the proximal epididymis.
', select the correct biomedical concept corresponding to 'he2'. Answer using one of the provided options. | <Options>: A: he1 (homo sapiens) (aka npc intracellular cholesterol transporter 2)
B: he3b (homo sapiens) (aka epididymal protein 3b)
C: he2c (homo sapiens) (aka sperm associated antigen 11b)
D: heg1 (homo sapiens) (aka heart development protein with egf like domains 1)
E: hebi2 (homo sapiens) (aka g protein-coupled receptor 183)
F: None of the above. | C |
<Instruct>: Given the context 'A novel human cDNA encoding a small secretory glycopeptide specifically expressed within the caput and proximal corpus regions of the human epididymis, HE2, has been cloned and sequenced.', select the correct biomedical concept corresponding to 'he2'. Answer using one of the provided options. | <Options>: A: hebi2 (homo sapiens) (aka g protein-coupled receptor 183)
B: heag2 (homo sapiens) (aka potassium voltage-gated channel subfamily h member 5)
C: he3b (homo sapiens) (aka epididymal protein 3b)
D: hey2 (homo sapiens) (aka hes related family bhlh transcription factor with yrpw motif 2)
E: he2c (homo sapiens) (aka sperm associated antigen 11b)
F: None of the above. | E |
<Instruct>: Given the context 'This recombinant HE2 protein, as well as an oligopeptide deduced from the open-reading frame, was used to raise polyclonal antisera.', select the correct biomedical concept corresponding to 'he2'. Answer using one of the provided options. | <Options>: A: heg (homo sapiens) (aka heart development protein with egf like domains 1)
B: he3b (homo sapiens) (aka epididymal protein 3b)
C: he2c (homo sapiens) (aka sperm associated antigen 11b)
D: hey2 (homo sapiens) (aka hes related family bhlh transcription factor with yrpw motif 2)
E: hebi2 (homo sapiens) (aka g protein-coupled receptor 183)
F: None of the above. | C |
<Instruct>: Given the context 'Immunohistochemistry and immunofluorescence showed that the predicted HE2 peptide is present in the epididymal epithelium and on the sperm surface, where it adopts a typical antigenic pattern with a subacrosomal equatorial distribution on the sperm head.', select the correct biomedical concept corresponding to 'he2'. Answer using one of the provided options. | <Options>: A: heg (homo sapiens) (aka heart development protein with egf like domains 1)
B: hebi2 (homo sapiens) (aka g protein-coupled receptor 183)
C: he1 (homo sapiens) (aka npc intracellular cholesterol transporter 2)
D: hey2 (homo sapiens) (aka hes related family bhlh transcription factor with yrpw motif 2)
E: he2c (homo sapiens) (aka sperm associated antigen 11b)
F: None of the above. | E |
<Instruct>: Given the context 'Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization.
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide and other pyridines.', select the correct biomedical concept corresponding to 'nicotinamide n-methyltransferase'. Answer using one of the provided options. | <Options>: A: nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis)) (aka provisional ortholog of nicotinamide n-methyltransferase)
B: nicotinamide n-methyltransferase (homo sapiens) (aka nicotinamide n-methyltransferase)
C: nicotinamide n-methyltransferase-like (caenorhabditis elegans) (aka nicotinamide n-methyltransferase-like)
D: nmt (homo sapiens) (aka n-myristoyltransferase 1)
E: nicotinamide n-methyltransferase (rattus norvegicus) (aka nicotinamide n-methyltransferase)
F: None of the above. | B |
<Instruct>: Given the context 'Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization.
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide and other pyridines.', select the correct biomedical concept corresponding to 'nicotinamide n-methyltransferase'. Answer using one of the provided options. | <Options>: A: nnmt (homo sapiens) (aka nicotinamide n-methyltransferase)
B: nicotinamide n-methyltransferase (mus musculus) (aka nicotinamide n-methyltransferase)
C: nmt1 (mus musculus) (aka n-myristoyltransferase 1)
D: nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis)) (aka provisional ortholog of nicotinamide n-methyltransferase)
E: nrmt (homo sapiens) (aka n-terminal xaa-pro-lys n-methyltransferase 1)
F: None of the above. | A |
<Instruct>: Given the context 'Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization.
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide and other pyridines.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nicotinamide n-methyltransferase (homo sapiens) (aka nicotinamide n-methyltransferase)
B: nnmt (rattus norvegicus) (aka nicotinamide n-methyltransferase)
C: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
D: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
E: nrmt (homo sapiens) (aka n-terminal xaa-pro-lys n-methyltransferase 1)
F: None of the above. | A |
<Instruct>: Given the context 'Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization.
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide and other pyridines.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nrmt (homo sapiens) (aka n-terminal xaa-pro-lys n-methyltransferase 1)
B: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
C: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
D: nnmt (rattus norvegicus) (aka nicotinamide n-methyltransferase)
E: nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis)) (aka provisional ortholog of nicotinamide n-methyltransferase)
F: None of the above. | F |
<Instruct>: Given the context 'Human liver NNMT activity has a bimodal frequency distribution, an observation which raises the possibility that this enzyme activity might be regulated by a genetic polymorphism, a polymorphism that could have functional implications for individual differences in drug and xenobiotic toxicity.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
B: nicotinamide n-methyltransferase (homo sapiens) (aka nicotinamide n-methyltransferase)
C: nrmt (homo sapiens) (aka n-terminal xaa-pro-lys n-methyltransferase 1)
D: nnmt (mus musculus) (aka nicotinamide n-methyltransferase)
E: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
F: None of the above. | B |
<Instruct>: Given the context 'As a first step toward testing that hypothesis, we set out to clone and express a cDNA for human liver NNMT.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nicotinamide n-methyltransferase (mus musculus) (aka nicotinamide n-methyltransferase)
B: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
C: nicotinamide n-methyltransferase (homo sapiens) (aka nicotinamide n-methyltransferase)
D: nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis)) (aka provisional ortholog of nicotinamide n-methyltransferase)
E: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
F: None of the above. | C |
<Instruct>: Given the context 'Human liver NNMT was partially purified, photoaffinity-labeled, subjected to limited proteolysis, and partial amino acid sequence information was obtained.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
B: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
C: nicotinamide n-methyltransferase (rattus norvegicus) (aka nicotinamide n-methyltransferase)
D: nnmt (mus musculus) (aka nicotinamide n-methyltransferase)
E: nnmt (homo sapiens) (aka nicotinamide n-methyltransferase)
F: None of the above. | E |
<Instruct>: Given the context 'The polymerase chain reaction was then used to amplify a 550-nucleotide sequence with human liver cDNA as template and primers designed on the basis of the NNMT amino acid sequence.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nicotinamide n-methyltransferase (homo sapiens) (aka nicotinamide n-methyltransferase)
B: nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis)) (aka provisional ortholog of nicotinamide n-methyltransferase)
C: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
D: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
E: nicotinamide n-methyltransferase (rattus norvegicus) (aka nicotinamide n-methyltransferase)
F: None of the above. | A |
<Instruct>: Given the context 'The 5'- and 3'-ends of a human liver NNMT cDNA were obtained by use of the rapid amplification of cDNA ends.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis)) (aka provisional ortholog of nicotinamide n-methyltransferase)
B: nnmt (mus musculus) (aka nicotinamide n-methyltransferase)
C: nicotinamide n-methyltransferase (homo sapiens) (aka nicotinamide n-methyltransferase)
D: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
E: nnmt (rattus norvegicus) (aka nicotinamide n-methyltransferase)
F: None of the above. | C |
<Instruct>: Given the context 'The combined use of these approaches resulted in the isolation of a human liver NNMT cDNA that was 969 nucleotides in length, with a 792-nucleotide open reading frame that encoded a 264-amino acid protein with a calculated molecular mass of 29.6 kDa.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nicotinamide n-methyltransferase (homo sapiens) (aka nicotinamide n-methyltransferase)
B: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
C: nicotinamide n-methyltransferase (rattus norvegicus) (aka nicotinamide n-methyltransferase)
D: nrmt (homo sapiens) (aka n-terminal xaa-pro-lys n-methyltransferase 1)
E: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
F: None of the above. | A |
<Instruct>: Given the context 'The human liver NNMT cDNA was transcribed in vitro and translated with a reticulocyte lysate system to yield a protein with a molecular mass of approximately 29 kDa that comigrated during SDS-polyacrylamide gel electrophoresis with photoaffinity-labeled human liver NNMT.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
B: nnmt (mus musculus) (aka nicotinamide n-methyltransferase)
C: nnmt (homo sapiens) (aka nicotinamide n-methyltransferase)
D: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
E: nnmt (rattus norvegicus) (aka nicotinamide n-methyltransferase)
F: None of the above. | C |
<Instruct>: Given the context 'The human liver NNMT cDNA was transcribed in vitro and translated with a reticulocyte lysate system to yield a protein with a molecular mass of approximately 29 kDa that comigrated during SDS-polyacrylamide gel electrophoresis with photoaffinity-labeled human liver NNMT.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
B: nicotinamide n-methyltransferase (rattus norvegicus) (aka nicotinamide n-methyltransferase)
C: nnmt (homo sapiens) (aka nicotinamide n-methyltransferase)
D: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
E: nnmt (mus musculus) (aka nicotinamide n-methyltransferase)
F: None of the above. | C |
<Instruct>: Given the context 'The NNMT cDNA was also subcloned into the eukaryotic expression vector p91023(B).', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nrmt (homo sapiens) (aka n-terminal xaa-pro-lys n-methyltransferase 1)
B: nnmt (homo sapiens) (aka nicotinamide n-methyltransferase)
C: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
D: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
E: nnmt (mus musculus) (aka nicotinamide n-methyltransferase)
F: None of the above. | B |
<Instruct>: Given the context 'COS-1 cells transfected with this construct expressed a high level of NNMT enzymatic activity, and the biochemical properties of this activity were similar to those of human liver NNMT.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nnmt (homo sapiens) (aka nicotinamide n-methyltransferase)
B: nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis)) (aka provisional ortholog of nicotinamide n-methyltransferase)
C: nicotinamide n-methyltransferase (rattus norvegicus) (aka nicotinamide n-methyltransferase)
D: nicotinamide n-methyltransferase (mus musculus) (aka nicotinamide n-methyltransferase)
E: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
F: None of the above. | A |
<Instruct>: Given the context 'COS-1 cells transfected with this construct expressed a high level of NNMT enzymatic activity, and the biochemical properties of this activity were similar to those of human liver NNMT.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nrmt (homo sapiens) (aka n-terminal xaa-pro-lys n-methyltransferase 1)
B: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
C: nicotinamide n-methyltransferase (rattus norvegicus) (aka nicotinamide n-methyltransferase)
D: nicotinamide n-methyltransferase (mus musculus) (aka nicotinamide n-methyltransferase)
E: nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis)) (aka provisional ortholog of nicotinamide n-methyltransferase)
F: None of the above. | F |
<Instruct>: Given the context 'COS-1 cells transfected with this construct expressed a high level of NNMT enzymatic activity, and the biochemical properties of this activity were similar to those of human liver NNMT.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
B: nicotinamide n-methyltransferase (mus musculus) (aka nicotinamide n-methyltransferase)
C: nicotinamide n-methyltransferase (rattus norvegicus) (aka nicotinamide n-methyltransferase)
D: nrmt (homo sapiens) (aka n-terminal xaa-pro-lys n-methyltransferase 1)
E: nnmt (homo sapiens) (aka nicotinamide n-methyltransferase)
F: None of the above. | E |
<Instruct>: Given the context 'Human liver NNMT and transfected COS-1 cell NNMT had apparent Km values for the two cosubstrates for the reaction, nicotinamide and S-adenosyl-L-methionine, of 0.43 and 0.38 mM and of 1.8 and 2.2 microM, respectively.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
B: nrmt (homo sapiens) (aka n-terminal xaa-pro-lys n-methyltransferase 1)
C: nicotinamide n-methyltransferase (mus musculus) (aka nicotinamide n-methyltransferase)
D: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
E: nicotinamide n-methyltransferase (homo sapiens) (aka nicotinamide n-methyltransferase)
F: None of the above. | E |
<Instruct>: Given the context 'Human liver NNMT and transfected COS-1 cell NNMT had apparent Km values for the two cosubstrates for the reaction, nicotinamide and S-adenosyl-L-methionine, of 0.43 and 0.38 mM and of 1.8 and 2.2 microM, respectively.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
B: nnmt (mus musculus) (aka nicotinamide n-methyltransferase)
C: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
D: nnmt (homo sapiens) (aka nicotinamide n-methyltransferase)
E: nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis)) (aka provisional ortholog of nicotinamide n-methyltransferase)
F: None of the above. | D |
<Instruct>: Given the context 'IC50 values for the inhibition of NNMT by N1-methylnicotinamide were 60 and 30 microns for human liver and COS-1 cell-expressed NNMT, respectively.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis)) (aka provisional ortholog of nicotinamide n-methyltransferase)
B: nicotinamide n-methyltransferase (homo sapiens) (aka nicotinamide n-methyltransferase)
C: nicotinamide n-methyltransferase (mus musculus) (aka nicotinamide n-methyltransferase)
D: nrmt (homo sapiens) (aka n-terminal xaa-pro-lys n-methyltransferase 1)
E: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
F: None of the above. | B |
<Instruct>: Given the context 'IC50 values for the inhibition of NNMT by N1-methylnicotinamide were 60 and 30 microns for human liver and COS-1 cell-expressed NNMT, respectively.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
B: nicotinamide n-methyltransferase (rattus norvegicus) (aka nicotinamide n-methyltransferase)
C: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
D: nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis)) (aka provisional ortholog of nicotinamide n-methyltransferase)
E: nicotinamide n-methyltransferase (homo sapiens) (aka nicotinamide n-methyltransferase)
F: None of the above. | E |
<Instruct>: Given the context 'Cloning of a cDNA for human liver NNMT will help make it possible to test the hypothesis that inheritance may play a role in the regulation of individual differences in human liver NNMT activity.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
B: nrmt (homo sapiens) (aka n-terminal xaa-pro-lys n-methyltransferase 1)
C: nicotinamide n-methyltransferase (rattus norvegicus) (aka nicotinamide n-methyltransferase)
D: nnmt (mus musculus) (aka nicotinamide n-methyltransferase)
E: nnmt (homo sapiens) (aka nicotinamide n-methyltransferase)
F: None of the above. | E |
<Instruct>: Given the context 'Cloning of a cDNA for human liver NNMT will help make it possible to test the hypothesis that inheritance may play a role in the regulation of individual differences in human liver NNMT activity.', select the correct biomedical concept corresponding to 'nnmt'. Answer using one of the provided options. | <Options>: A: nrmt (homo sapiens) (aka n-terminal xaa-pro-lys n-methyltransferase 1)
B: nnt (mus musculus) (aka nicotinamide nucleotide transhydrogenase)
C: nnmt (homo sapiens) (aka nicotinamide n-methyltransferase)
D: nnmt (mus musculus) (aka nicotinamide n-methyltransferase)
E: nnt (homo sapiens) (aka nicotinamide nucleotide transhydrogenase)
F: None of the above. | C |
<Instruct>: Given the context 'Purification and characterization of the recombinant human calcium-binding S100 proteins CAPL and CACY.
', select the correct biomedical concept corresponding to 'capl'. Answer using one of the provided options. | <Options>: A: capl (mus musculus) (aka s100 calcium binding protein a4)
B: caprin-2-like (xenopus laevis) (aka caprin-2-like)
C: capl (homo sapiens) (aka s100 calcium binding protein a4)
D: capsl (homo sapiens) (aka calcyphosine like)
E: capsl (mus musculus) (aka calcyphosine-like)
F: None of the above. | C |
<Instruct>: Given the context 'Purification and characterization of the recombinant human calcium-binding S100 proteins CAPL and CACY.
', select the correct biomedical concept corresponding to 'cacy'. Answer using one of the provided options. | <Options>: A: cacy (homo sapiens) (aka s100 calcium binding protein a6)
B: cacy (mus musculus) (aka s100 calcium binding protein a6 (calcyclin))
C: cyy-1 (caenorhabditis elegans) (aka cyclin-y)
D: ccny (homo sapiens) (aka cyclin y)
E: caly (homo sapiens) (aka calcyon neuron specific vesicular protein)
F: None of the above. | A |
<Instruct>: Given the context 'The S100 proteins CAPL and CACY are expressed in a tissue- and cell-specific manner and have been reported to be associated with the metastatic phenotype of tumor cells.', select the correct biomedical concept corresponding to 'capl'. Answer using one of the provided options. | <Options>: A: caprin-2-like (xenopus laevis) (aka caprin-2-like)
B: capon (homo sapiens) (aka nitric oxide synthase 1 adaptor protein)
C: capsl (bos taurus) (aka calcyphosine like)
D: capl (homo sapiens) (aka s100 calcium binding protein a4)
E: capn1 (homo sapiens) (aka calpain 1)
F: None of the above. | D |
<Instruct>: Given the context 'The S100 proteins CAPL and CACY are expressed in a tissue- and cell-specific manner and have been reported to be associated with the metastatic phenotype of tumor cells.', select the correct biomedical concept corresponding to 'capl'. Answer using one of the provided options. | <Options>: A: capon (homo sapiens) (aka nitric oxide synthase 1 adaptor protein)
B: capn1 (homo sapiens) (aka calpain 1)
C: cmap-like (bos taurus) (aka cystatin f)
D: capsl (homo sapiens) (aka calcyphosine like)
E: capsl (bos taurus) (aka calcyphosine like)
F: None of the above. | F |
<Instruct>: Given the context 'The S100 proteins CAPL and CACY are expressed in a tissue- and cell-specific manner and have been reported to be associated with the metastatic phenotype of tumor cells.', select the correct biomedical concept corresponding to 'cacy'. Answer using one of the provided options. | <Options>: A: cacy (homo sapiens) (aka s100 calcium binding protein a6)
B: cyy-1 (caenorhabditis elegans) (aka cyclin-y)
C: caly (homo sapiens) (aka calcyon neuron specific vesicular protein)
D: caca (homo sapiens) (aka crystallin gamma d)
E: cacy (mus musculus) (aka s100 calcium binding protein a6 (calcyclin))
F: None of the above. | A |
<Instruct>: Given the context 'The isotherms show slight (CAPL, nH = 1.15) or pronounced (CACY, nH = 1.33) positive cooperativity with K0.5 values of 0.32 mM (CACY) and 0.15 mM (CAPL), indicating that the sites are of the low-affinity type.', select the correct biomedical concept corresponding to 'capl'. Answer using one of the provided options. | <Options>: A: caprin-2-like (xenopus laevis) (aka caprin-2-like)
B: capl (homo sapiens) (aka s100 calcium binding protein a4)
C: capn1 (homo sapiens) (aka calpain 1)
D: cartilage-associated protein-like (bos taurus) (aka cartilage-associated protein-like)
E: capsl (bos taurus) (aka calcyphosine like)
F: None of the above. | B |
<Instruct>: Given the context 'The isotherms show slight (CAPL, nH = 1.15) or pronounced (CACY, nH = 1.33) positive cooperativity with K0.5 values of 0.32 mM (CACY) and 0.15 mM (CAPL), indicating that the sites are of the low-affinity type.', select the correct biomedical concept corresponding to 'cacy'. Answer using one of the provided options. | <Options>: A: casy-1 (caenorhabditis elegans) (aka calsyntenin c-terminal domain-containing protein;secreted calsyntenin-1)
B: cyy-1 (caenorhabditis elegans) (aka cyclin-y)
C: cacy (mus musculus) (aka s100 calcium binding protein a6 (calcyclin))
D: cky-1 (caenorhabditis elegans) (aka pas domain-containing protein cky-1)
E: cacy (homo sapiens) (aka s100 calcium binding protein a6)
F: None of the above. | E |
<Instruct>: Given the context 'The isotherms show slight (CAPL, nH = 1.15) or pronounced (CACY, nH = 1.33) positive cooperativity with K0.5 values of 0.32 mM (CACY) and 0.15 mM (CAPL), indicating that the sites are of the low-affinity type.', select the correct biomedical concept corresponding to 'cacy'. Answer using one of the provided options. | <Options>: A: caly (homo sapiens) (aka calcyon neuron specific vesicular protein)
B: cky-1 (caenorhabditis elegans) (aka pas domain-containing protein cky-1)
C: cacy (homo sapiens) (aka s100 calcium binding protein a6)
D: caca (homo sapiens) (aka crystallin gamma d)
E: cacy (mus musculus) (aka s100 calcium binding protein a6 (calcyclin))
F: None of the above. | C |
<Instruct>: Given the context 'The isotherms show slight (CAPL, nH = 1.15) or pronounced (CACY, nH = 1.33) positive cooperativity with K0.5 values of 0.32 mM (CACY) and 0.15 mM (CAPL), indicating that the sites are of the low-affinity type.', select the correct biomedical concept corresponding to 'capl'. Answer using one of the provided options. | <Options>: A: capsl (mus musculus) (aka calcyphosine-like)
B: cmap-like (bos taurus) (aka cystatin f)
C: capl (homo sapiens) (aka s100 calcium binding protein a4)
D: caprin-2-like (xenopus laevis) (aka caprin-2-like)
E: capsl (homo sapiens) (aka calcyphosine like)
F: None of the above. | C |
<Instruct>: Given the context 'Conformational changes in the Tyr microenvironment of CACY indicate that Ca2+ binding induces a shift of Tyr to a less polar environment.', select the correct biomedical concept corresponding to 'cacy'. Answer using one of the provided options. | <Options>: A: ccny (homo sapiens) (aka cyclin y)
B: cacy (homo sapiens) (aka s100 calcium binding protein a6)
C: casy-1 (caenorhabditis elegans) (aka calsyntenin c-terminal domain-containing protein;secreted calsyntenin-1)
D: caca (homo sapiens) (aka crystallin gamma d)
E: cky-1 (caenorhabditis elegans) (aka pas domain-containing protein cky-1)
F: None of the above. | B |
<Instruct>: Given the context 'The Ca(2+)-induced difference spectra of CAPL are about 3 times smaller than those of CACY, suggesting that the additional Tyr84 in CACY is much more sensitive to Ca2+ than the two Tyr residues conserved in both proteins.', select the correct biomedical concept corresponding to 'capl'. Answer using one of the provided options. | <Options>: A: capl (homo sapiens) (aka s100 calcium binding protein a4)
B: cartilage-associated protein-like (bos taurus) (aka cartilage-associated protein-like)
C: capsl (bos taurus) (aka calcyphosine like)
D: capn1 (homo sapiens) (aka calpain 1)
E: capsl (mus musculus) (aka calcyphosine-like)
F: None of the above. | A |
<Instruct>: Given the context 'The Ca(2+)-induced difference spectra of CAPL are about 3 times smaller than those of CACY, suggesting that the additional Tyr84 in CACY is much more sensitive to Ca2+ than the two Tyr residues conserved in both proteins.', select the correct biomedical concept corresponding to 'cacy'. Answer using one of the provided options. | <Options>: A: ccny (homo sapiens) (aka cyclin y)
B: cacy (mus musculus) (aka s100 calcium binding protein a6 (calcyclin))
C: cacy (homo sapiens) (aka s100 calcium binding protein a6)
D: coy1 (homo sapiens) (aka cut like homeobox 1)
E: casy-1 (caenorhabditis elegans) (aka calsyntenin c-terminal domain-containing protein;secreted calsyntenin-1)
F: None of the above. | C |
<Instruct>: Given the context 'The Ca(2+)-induced difference spectra of CAPL are about 3 times smaller than those of CACY, suggesting that the additional Tyr84 in CACY is much more sensitive to Ca2+ than the two Tyr residues conserved in both proteins.', select the correct biomedical concept corresponding to 'cacy'. Answer using one of the provided options. | <Options>: A: cacy (homo sapiens) (aka s100 calcium binding protein a6)
B: caly (homo sapiens) (aka calcyon neuron specific vesicular protein)
C: coy1 (homo sapiens) (aka cut like homeobox 1)
D: casy-1 (caenorhabditis elegans) (aka calsyntenin c-terminal domain-containing protein;secreted calsyntenin-1)
E: cyy-1 (caenorhabditis elegans) (aka cyclin-y)
F: None of the above. | A |
<Instruct>: Given the context 'X-arrestin: a new retinal arrestin mapping to the X chromosome.
', select the correct biomedical concept corresponding to 'x-arrestin'. Answer using one of the provided options. | <Options>: A: arrestin (xenopus laevis) (arrestin beta 1 s homeolog (xenopus laevis)) (aka arrestin beta 1 s homeolog)
B: arr (drosophila melanogaster) (arrestin 2 (drosophila melanogaster)) (aka arrestin 2)
C: arr (drosophila melanogaster) (arrestin 1 (drosophila melanogaster)) (aka arrestin 1)
D: arrx (homo sapiens) (aka arrestin 3)
E: arrestin 3, retinal (x-arrestin) (xenopus tropicalis) (aka arrestin 3, retinal (x-arrestin))
F: None of the above. | D |
<Instruct>: Given the context 'X-arrestin: a new retinal arrestin mapping to the X chromosome.
', select the correct biomedical concept corresponding to 'x-arrestin'. Answer using one of the provided options. | <Options>: A: arrestin 3, retinal (x-arrestin) l homeolog (xenopus laevis) (aka arrestin 3, retinal (x-arrestin) l homeolog)
B: arrestin (xenopus laevis) (arrestin beta 2 l homeolog (xenopus laevis)) (aka arrestin beta 2 l homeolog)
C: arrestin 3, retinal (x-arrestin) (xenopus tropicalis) (aka arrestin 3, retinal (x-arrestin))
D: arrestin (xenopus laevis) (arrestin beta 1 s homeolog (xenopus laevis)) (aka arrestin beta 1 s homeolog)
E: arrestin (xenopus laevis) (arrestin beta 2 s homeolog (xenopus laevis)) (aka arrestin beta 2 s homeolog)
F: None of the above. | F |
<Instruct>: Given the context 'Chromosomal mapping localized this new arrestin gene to the proximal long arm of the X chromosome, hence it was named X-arrestin.', select the correct biomedical concept corresponding to 'x-arrestin'. Answer using one of the provided options. | <Options>: A: arrx (homo sapiens) (aka arrestin 3)
B: arrestin (xenopus laevis) (arrestin beta 1 s homeolog (xenopus laevis)) (aka arrestin beta 1 s homeolog)
C: arr (drosophila melanogaster) (arrestin 2 (drosophila melanogaster)) (aka arrestin 2)
D: arrestin 3, retinal (x-arrestin) (xenopus tropicalis) (aka arrestin 3, retinal (x-arrestin))
E: arrestin (xenopus laevis) (arrestin beta 2 s homeolog (xenopus laevis)) (aka arrestin beta 2 s homeolog)
F: None of the above. | A |
<Instruct>: Given the context 'Human G(olf) alpha: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system.
G(olf) alpha is a G-protein originally believed to mediate signal transduction exclusively within the olfactory neuroepithelium and subsequently found to be a major stimulatory G-protein in the basal ganglia.', select the correct biomedical concept corresponding to 'g(olf) alpha'. Answer using one of the provided options. | <Options>: A: g protein subunit alpha l (homo sapiens) (aka g protein subunit alpha l)
B: gnas/l (drosophila melanogaster) (g protein alpha subunit f (drosophila melanogaster)) (aka g protein alpha subunit f)
C: guanine nucleotide-binding protein alpha-1 subunit (glycine max) (aka guanine nucleotide-binding protein alpha-1 subunit)
D: g(olf) (xenopus laevis) (g protein subunit alpha l s homeolog (xenopus laevis)) (aka g protein subunit alpha l s homeolog)
E: g protein alpha subunit (glycine max) (aka g protein alpha subunit)
F: None of the above. | A |
<Instruct>: Given the context 'Human G(olf) alpha: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system.
G(olf) alpha is a G-protein originally believed to mediate signal transduction exclusively within the olfactory neuroepithelium and subsequently found to be a major stimulatory G-protein in the basal ganglia.', select the correct biomedical concept corresponding to 'g(olf) alpha'. Answer using one of the provided options. | <Options>: A: g protein subunit alpha l (homo sapiens) (aka g protein subunit alpha l)
B: galpha(olf) (xenopus tropicalis) (aka g protein subunit alpha l)
C: guanine nucleotide-binding protein alpha-1 subunit (glycine max) (aka guanine nucleotide-binding protein alpha-1 subunit)
D: g(olf) (xenopus laevis) (g protein subunit alpha l s homeolog (xenopus laevis)) (aka g protein subunit alpha l s homeolog)
E: g(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis)) (aka g protein subunit alpha l l homeolog)
F: None of the above. | A |
<Instruct>: Given the context 'Here we present evidence that G(olf) alpha is expressed in several other tissues.', select the correct biomedical concept corresponding to 'g(olf) alpha'. Answer using one of the provided options. | <Options>: A: g protein subunit alpha l (homo sapiens) (aka g protein subunit alpha l)
B: galpha(olf) (xenopus tropicalis) (aka g protein subunit alpha l)
C: galpha(olf) (xenopus laevis) (g protein subunit alpha l s homeolog (xenopus laevis)) (aka g protein subunit alpha l s homeolog)
D: guanine nucleotide-binding protein g(olf) subunit alpha-like (oryctolagus cuniculus) (aka guanine nucleotide-binding protein g(olf) subunit alpha-like)
E: galpha(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis)) (aka g protein subunit alpha l l homeolog)
F: None of the above. | A |
<Instruct>: Given the context 'The human isoform of G(olf) alpha was isolated from two human insulinoma cDNA libraries.', select the correct biomedical concept corresponding to 'g(olf) alpha'. Answer using one of the provided options. | <Options>: A: guanine nucleotide-binding protein alpha-1 subunit (glycine max) (aka guanine nucleotide-binding protein alpha-1 subunit)
B: g protein alpha subunit (glycine max) (aka g protein alpha subunit)
C: galpha(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis)) (aka g protein subunit alpha l l homeolog)
D: galpha(olf) (xenopus laevis) (g protein subunit alpha l s homeolog (xenopus laevis)) (aka g protein subunit alpha l s homeolog)
E: g protein subunit alpha l (homo sapiens) (aka g protein subunit alpha l)
F: None of the above. | E |
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