instruction stringlengths 225 2.35k | input stringlengths 89 1.5k | response stringclasses 698 values |
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<Instruct>: Given the context 'In: Proceedings of the Third Colloquium on Particulate Air Pollution and Human Health (Phalen RF, Bell YM, eds).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: suborder
B: primate (aka primates)
C: biota (aka cellular organisms)
D: species
E: None of the above. | [E] |
<Instruct>: Given the context 'An association between fine particles and asthma emergency department visits for children in Seattle.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [children]
<Options>: A: suborder
B: menetus
C: genus
D: chicken (aka gallus gallus)
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'Hamada K, Goldsmith CW, Kobzik L. Air pollutant aerosols allow airway sensitization to allergen in juvenile mice. Am J Resp Crit Care Med A28 (1999).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: mus musculus (house mouse) (aka mus musculus)
C: mus sp. (mice (aka mus sp.))
D: peromyscus
E: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
F: None of the above. | [B] |
<Instruct>: Given the context 'Residual oil fly ash exposure enhances allergic sensitization to house dust mite in rats and augments immune-mediated inflammation', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rats]
<Options>: A: rattus norvegicus albus
B: house rat (aka rattus rattus)
C: rats (aka rattus) (aka rattus)
D: rats (aka rattus sp.) (aka rattus sp.)
E: rat (aka rattus norvegicus) (aka rattus norvegicus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Salvi S, Blomberg A, Rudell B, Kelly F, Sandstrom T, Holgate ST, Frew A. Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: human (aka homo sapiens)
B: cellular organisms (biota) (aka cellular organisms)
C: eutherian mammals (aka eutheria)
D: animals (aka metazoa)
E: humans (aka homo)
F: None of the above. | [A] |
<Instruct>: Given the context 'Pulmonary and cardiovascular effects of acute exposure to concentrated ambient particulate matter in rats. Toxicol Lett 96�97:285�288 (1998).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rats]
<Options>: A: rats (aka rattus sp.) (aka rattus sp.)
B: rattus norvegicus albus
C: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
D: mus norvegicus (aka rattus norvegicus)
E: rattus (rats (aka rattus))
F: None of the above. | [D] |
<Instruct>: Given the context 'Physiological and chemical characterization of cyanobacterial metallothioneins.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cyanobacterial]
<Options>: A: cyanobacteria bacterium (aka cyanobacteriota bacterium)
B: green algae (aka chlorophyta)
C: cyanophyceae cyanobacterium (cyanophyceae bacterium) (aka cyanophyceae cyanobacterium)
D: cyanophyta (aka cyanobacteriota)
E: algae (aka dinophyceae)
F: None of the above. | [D] |
<Instruct>: Given the context 'Differential pulse polarographic wave for murine MT-1.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [murine]
<Options>: A: mus musculus (house mouse) (aka mus musculus)
B: eastern european house mouse (aka mus musculus musculus)
C: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
D: mus <subgenus> (mus (aka mus <subgenus>))
E: mice (aka mus <genus>) (aka mus <genus>)
F: None of the above. | [A] |
<Instruct>: Given the context '72
CYANOBACTERIAL METALLOTHIONEINS
Isolation of Cyanobacterial MT
Synechococcus strain Tx-20 cyanobacteria were maintained in axenic culture on BG-11 medium (7) and harvested from aerated 20 L cultures grown at 280C under fluorescent light.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cyanobacterial]
<Options>: A: algae (aka dinophyceae)
B: cyanobacterium
C: green algae (aka chlorophyta)
D: cyanobacteriaceae (aka geminocystaceae)
E: cyanobacteria (aka cyanobacteriota)
F: None of the above. | [E] |
<Instruct>: Given the context 'Nearest integer residues per molecule Human (MT-2) Crab (MT-2) ', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: placental mammals (aka eutheria)
B: genus
C: human (aka homo sapiens)
D: birds (aka aves)
E: species
F: None of the above. | [C] |
<Instruct>: Given the context 'A I D R N G L Y Y Scylla P DP C C NDK C DC K EG EC KT GC K CT S C Human Ac MD P NC S C AA G DS CT C AG S C KC KE C KC T S C
Neurospora
G D C G C S G', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: human (aka homo sapiens)
B: genus
C: this
D: birds (aka aves)
E: animals (aka metazoa)
F: None of the above. | [A] |
<Instruct>: Given the context 'A I D R N G L Y Y Scylla P DP C C NDK C DC K EG EC KT GC K CT S C Human Ac MD P NC S C AA G DS CT C AG S C KC KE C KC T S C
Neurospora
G D C G C S G', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: animals (aka metazoa)
B: birds (aka aves)
C: genus
D: this
E: None of the above. | [E] |
<Instruct>: Given the context 'I I
CYANOBACTERIAL METALLOTHIONEINS 75
cadmium or zinc was due to a rather protracted time of MT induction, perhaps associated with toxic burden.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cyanobacterial]
<Options>: A: algae (aka chlorokybophyceae)
B: blue-green bacteria (aka cyanobacteriota)
C: cyanobacteria bacterium (aka cyanobacteriota bacterium)
D: algae (aka dinophyceae)
E: cyanobacteriaceae (aka geminocystaceae)
F: None of the above. | [B] |
<Instruct>: Given the context 'Structure of Cyanobacterial MT
The structural determination of cyanobacterial MT is not yet complete, although a substantial amount of information is now known.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cyanobacterial]
<Options>: A: cyanobacterium
B: blue-green algae (aka cyanobacteriota)
C: algae (aka dinophyceae)
D: nostocales cyanobacterium (nostocales bacterium) (aka nostocales cyanobacterium)
E: algae (aka chlorophyta)
F: None of the above. | [B] |
<Instruct>: Given the context 'With the exception of the typical Cys-X-Cys sequences, the first 42 residues of the prokaryotic MT were essentially without homology on comparison with the crab (Scylla), human, or Neurospora crassa MTs (Table 2).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [crab; scylla; human; neurospora crassa]
<Options>: A: chrysonilia crassa (aka neurospora crassa)
B: ophiocordyceps crassispora (cordyceps crassispora) (aka ophiocordyceps crassispora)
C: neurospora cratophora (gelasinospora cratophora) (aka neurospora cratophora)
D: scyllarides
E: homo sapiens (human) (aka homo sapiens)
F: neurospora crassa 1211
G: mangrove crabs (aka scylla)
H: short-tailed crabs (aka brachyura)
I: scobura
J: genus
K: suborder
L: rock crabs (aka cancridae)
M: swimming crabs (aka portunidae)
N: sibylla
O: scyllaridae sp.
P: mud crabs (aka xanthoidea)
Q: species
R: probles
S: amyloporiella crassa (aka resinoporia crassa)
T: None of the above. | [G; G; E; A] |
<Instruct>: Given the context 'With the exception of the typical Cys-X-Cys sequences, the first 42 residues of the prokaryotic MT were essentially without homology on comparison with the crab (Scylla), human, or Neurospora crassa MTs (Table 2).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [crab; scylla; human; neurospora crassa]
<Options>: A: mud crabs (aka scylla)
B: dalla scylla (butleria scylla) (aka dalla scylla)
C: biota (aka cellular organisms)
D: neurospora nigeriensis
E: sphaerospermopsis crassa
F: macrobiotus sapiens
G: frog crabs (aka raninidae)
H: crabro
I: homo sapiens (human) (aka homo sapiens)
J: neurospora crassa (chrysonilia crassa) (aka neurospora crassa)
K: kingdom
L: scyllarides
M: neurospora crassa 1211
N: papilio scylla (aka catopsilia scylla)
O: crabroninae
P: mud crabs (aka xanthoidea)
Q: microceris scylla (microceris scylla (menetries, 1855)) (aka microceris scylla)
R: cordyceps crassispora (aka ophiocordyceps crassispora)
S: placental mammals (aka eutheria)
T: None of the above. | [A; A; I; J] |
<Instruct>: Given the context 'With the exception of the typical Cys-X-Cys sequences, the first 42 residues of the prokaryotic MT were essentially without homology on comparison with the crab (Scylla), human, or Neurospora crassa MTs (Table 2).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [crab; scylla; human; neurospora crassa]
<Options>: A: sphaerospermopsis crassa
B: microceris scylla (microceris scylla (menetries, 1855)) (aka microceris scylla)
C: crabroninae
D: placental mammals (aka eutheria)
E: biota (aka cellular organisms)
F: homo sapiens (human) (aka homo sapiens)
G: kingdom
H: cordyceps crassispora (aka ophiocordyceps crassispora)
I: frog crabs (aka raninidae)
J: neurospora crassa 1211
K: dalla scylla (butleria scylla) (aka dalla scylla)
L: papilio scylla (aka catopsilia scylla)
M: macrobiotus sapiens
N: neurospora crassa (chrysonilia crassa) (aka neurospora crassa)
O: mud crabs (aka xanthoidea)
P: crabro
Q: scyllarides
R: neurospora nigeriensis
S: None of the above. | [S; S; F; N] |
<Instruct>: Given the context 'With the exception of the typical Cys-X-Cys sequences, the first 42 residues of the prokaryotic MT were essentially without homology on comparison with the crab (Scylla), human, or Neurospora crassa MTs (Table 2).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [crab; scylla; human; neurospora crassa]
<Options>: A: neurospora crassa (chrysonilia crassa) (aka neurospora crassa)
B: crabroninae
C: scyllaridae (slipper lobsters) (aka scyllaridae)
D: neurospora
E: crabbea
F: mud crabs (aka scylla)
G: neurospora nigeriensis
H: amyloporiella crassa (aka resinoporia crassa)
I: papilio scylla (aka catopsilia scylla)
J: neurospora crassa 1211
K: birds (aka aves)
L: suborder
M: scyllarides
N: land crabs (aka gecarcinidae)
O: scyllarus latus (aka scyllarides latus)
P: macrobiotus sapiens
Q: genus
R: box crabs (aka calappidae)
S: human (aka homo sapiens)
T: None of the above. | [F; F; S; A] |
<Instruct>: Given the context 'With the exception of the typical Cys-X-Cys sequences, the first 42 residues of the prokaryotic MT were essentially without homology on comparison with the crab (Scylla), human, or Neurospora crassa MTs (Table 2).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [crab; scylla; human; neurospora crassa]
<Options>: A: scyllarus
B: probles
C: primate (aka primates)
D: swimming crabs (aka portunidae)
E: crabronidae
F: land crabs (aka gecarcinidae)
G: scyllaridae (slipper lobsters) (aka scyllaridae)
H: cordyceps crassispora (aka ophiocordyceps crassispora)
I: neurospora crassa (chrysonilia crassa) (aka neurospora crassa)
J: distoseptispora crassispora
K: this
L: sphaerospermopsis crassa
M: homo sapiens (human) (aka homo sapiens)
N: mud crabs (aka scylla)
O: neurospora sp.
P: butleria scylla (aka dalla scylla)
Q: suborder
R: scylla sp.
S: horseshoe crabs (aka merostomata)
T: None of the above. | [N; N; M; I] |
<Instruct>: Given the context 'Birk
hauser Verlag, Basel, 1979, pp. 5-55.
2. Olafson, R. W Differential pulse polarographic determination of
murine metallothionein induction kinetics.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [murine]
<Options>: A: mice (aka mus sp.) (aka mus sp.)
B: mus cricetus (aka cricetus cricetus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: house mouse (aka mus musculus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | [D] |
<Instruct>: Given the context 'Olafson, R. W Intestinal metallothionein: effect of parenteral and
enteral zinc exposure on tissue levels of mice on controlled zinc diets.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: eastern european house mouse (aka mus musculus musculus)
B: mus domesticus (aka mus musculus domesticus)
C: mus (aka mus <genus>) (aka mus <genus>)
D: house mouse (aka mus musculus)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [D] |
<Instruct>: Given the context 'Olafson, R. W Intestinal metallothionein: effect of parenteral and
enteral zinc exposure on tissue levels of mice on controlled zinc diets.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: eastern european house mouse (aka mus musculus musculus)
B: mus domesticus (aka mus musculus domesticus)
C: mus castaneus (aka mus musculus castaneus)
D: mus (aka mus <genus>) (aka mus <genus>)
E: None of the above. | [E] |
<Instruct>: Given the context 'McCarter, J.A., and Roch, M. Chronic exposure of Coho salmon
to sublethal concentrations of copper.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [coho salmon]
<Options>: A: coho salmon (aka oncorhynchus kisutch)
B: oncorhynchus gilae (salmo gilae) (aka oncorhynchus gilae)
C: cherry salmon (aka oncorhynchus masou)
D: salmonidae (salmonids) (aka salmonidae)
E: chum salmon (aka oncorhynchus keta)
F: None of the above. | [A] |
<Instruct>: Given the context 'Otvos, J. D., Olafson, R.W, and Armitage, I. M. Structure of an
invertebrate metallothionein from Scylla serrata.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [scylla serrata]
<Options>: A: frullania serrata
B: scutellaria serrata
C: giant mud crab (aka scylla serrata)
D: dixa serrata
E: hyla serrata (aka ranoidea serrata)
F: None of the above. | [C] |
<Instruct>: Given the context 'Olafson, R. W Differential pulse polarographic determination of
murine metallothionein induction kinetics.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [murine]
<Options>: A: house mouse (aka mus musculus)
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mus cricetus (aka cricetus cricetus)
D: mice (aka mus sp.) (aka mus sp.)
E: mus (aka mus <genus>) (aka mus <genus>)
F: None of the above. | [A] |
<Instruct>: Given the context 'Finally, we observed that all markers expressed during the transcriptional control of hippocampal neurogenesis in rodents are also present in the human hippocampus.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: primate (aka primates)
B: this
C: human (aka homo sapiens)
D: suborder
E: species
F: None of the above. | [C] |
<Instruct>: Given the context 'In both rodent and human adult brain, neurogenesis is active in two distinct zones of the forebrain: the subventricular zone (SVZ) of the lateral ventricle and the subgranular zone (SGZ) of the hippocampal dentate gyrus (DG)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rodent; human]
<Options>: A: homo (humans) (aka homo)
B: mus norvegicus (aka rattus norvegicus)
C: rodent (aka rodentia)
D: mus musculus (house mouse) (aka mus musculus)
E: genus
F: suborder
G: human (aka homo sapiens)
H: birds (aka aves)
I: mus domesticus (aka mus musculus domesticus)
J: probles
K: None of the above. | [C; G] |
<Instruct>: Given the context 'In both rodent and human adult brain, neurogenesis is active in two distinct zones of the forebrain: the subventricular zone (SVZ) of the lateral ventricle and the subgranular zone (SGZ) of the hippocampal dentate gyrus (DG)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rodent; human]
<Options>: A: species
B: mammals (aka mammalia)
C: mice (aka mus sp.) (aka mus sp.)
D: eutherian mammals (aka eutheria)
E: homo sapiens (human) (aka homo sapiens)
F: suborder
G: mus domesticus (aka mus musculus domesticus)
H: probles
I: rodents (aka rodentia)
J: house mouse (aka mus musculus)
K: None of the above. | [I; E] |
<Instruct>: Given the context 'Finally, we demonstrate that the same transcription factors and cellular markers seen in mouse and rat tissue are also present in the human hippocampus.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse; rat; human]
<Options>: A: rattus rattoides (aka rattus pyctoris)
B: rattus norvegicus albus
C: mice (aka mus <genus>) (aka mus <genus>)
D: mouse (aka mus musculus)
E: human (aka homo sapiens)
F: probles
G: house rat (aka rattus rattus)
H: peromyscus
I: this
J: avian (aka aves)
K: rats (aka rattus sp.) (aka rattus sp.)
L: eastern european house mouse (aka mus musculus musculus)
M: primate (aka primates)
N: norway rat (aka rattus norvegicus)
O: mice (aka mus sp.) (aka mus sp.)
P: None of the above. | [D; N; E] |
<Instruct>: Given the context 'Finally, we demonstrate that the same transcription factors and cellular markers seen in mouse and rat tissue are also present in the human hippocampus.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse; rat; human]
<Options>: A: eastern european house mouse (aka mus musculus musculus)
B: peromyscus
C: norway rat (aka rattus norvegicus)
D: mus musculus (house mouse) (aka mus musculus)
E: mammals (aka mammalia)
F: this
G: rattus norvegicus albus
H: mus cricetus (aka cricetus cricetus)
I: rattus rattus (rattus wroughtoni) (aka rattus rattus)
J: rat (aka rattus) (aka rattus)
K: genus
L: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
M: kingdom
N: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
O: homo sapiens (human) (aka homo sapiens)
P: None of the above. | [D; C; O] |
<Instruct>: Given the context 'Finally, we demonstrate that the same transcription factors and cellular markers seen in mouse and rat tissue are also present in the human hippocampus.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse; rat; human]
<Options>: A: suborder
B: probles
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: mus norvegicus (aka rattus norvegicus)
E: mus <genus> (mice (aka mus <genus>))
F: this
G: rattus norvegicus albus
H: roof rat (aka rattus rattus)
I: genus
J: mus domesticus (aka mus musculus domesticus)
K: mus molossinus (aka mus musculus molossinus)
L: human (aka homo sapiens)
M: mouse (aka mus musculus)
N: rats (aka rattus sp.) (aka rattus sp.)
O: rattus (rats (aka rattus))
P: None of the above. | [M; D; L] |
<Instruct>: Given the context 'In the adult mouse DG, only a very small proportion of cells undergo mitosis at any one given time [22].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse]
<Options>: A: western european house mouse (aka mus musculus domesticus)
B: mus sp. (mice (aka mus sp.))
C: peromyscus
D: mouse (aka mus musculus)
E: mus <subgenus> (mus (aka mus <subgenus>))
F: None of the above. | [D] |
<Instruct>: Given the context 'We performed triple immunohistochemistry for all markers of interest and compared results from 2 week- and 2 month-old mice (Figure 1 and figure S1).
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus cricetus (aka cricetus cricetus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: mus <genus> (mice (aka mus <genus>))
F: None of the above. | [A] |
<Instruct>: Given the context 'In the SGZ of 2 week-old mice, we found an average of 50–70 Tbr2+ cells per 30 µm-thick section throughout the rostro-caudal axis of the dorsal hippocampus.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus sp. (mice (aka mus sp.))
B: mus musculus (house mouse) (aka mus musculus)
C: eastern european house mouse (aka mus musculus musculus)
D: western european house mouse (aka mus musculus domesticus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | [B] |
<Instruct>: Given the context 'In the SGZ of 2 week-old mice, we found an average of 50–70 Tbr2+ cells per 30 µm-thick section throughout the rostro-caudal axis of the dorsal hippocampus.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: eastern european house mouse (aka mus musculus musculus)
B: mus sp. (mice (aka mus sp.))
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: western european house mouse (aka mus musculus domesticus)
E: None of the above. | [E] |
<Instruct>: Given the context 'This number was reduced by 35% in 2 month-old mice (Figure 1C with figure S1C and data not shown).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus domesticus (aka mus musculus domesticus)
B: mus (aka mus <genus>) (aka mus <genus>)
C: mus cricetus (aka cricetus cricetus)
D: house mouse (aka mus musculus)
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | [D] |
<Instruct>: Given the context 'Mash1 and Ngn2 define the early versus late type-2a stage in 2 weeks old mice
Having established the hierarchy of transcription factors and cellular markers appearing during hippocampal neurogenesis, we set out to clarify the position of the two bHLH transcription factors Ngn2 and Mash1, in this process.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus castaneus (aka mus musculus castaneus)
B: mouse (aka mus <genus>)
C: mus musculus (house mouse) (aka mus musculus)
D: mus sp. (mice (aka mus sp.))
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | [C] |
<Instruct>: Given the context 'However, it is present, as previously described using reporter mice and as revealed by in situ hybridization', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: peromyscus
C: mus (aka mus <genus>) (aka mus <genus>)
D: mus musculus (house mouse) (aka mus musculus)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | [D] |
<Instruct>: Given the context 'Ngn2 progenies become hippocampal granule neurons
Previous work has shown that in Mash1 null mutant mice hippocampal neurogenesis is not reduced and the hippocampus is not malformed [20].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus castaneus (aka mus musculus castaneus)
B: house mouse (aka mus musculus)
C: western european house mouse (aka mus musculus domesticus)
D: mus sp. (mice (aka mus sp.))
E: mus <subgenus> (mus (aka mus <subgenus>))
F: None of the above. | [B] |
<Instruct>: Given the context 'We characterized the fate of Ngn2-expressing cells using Ngn2 Knock-in green fluorescent protein (GFP) mice (Ngn2+/GFP)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus castaneus (aka mus musculus castaneus)
B: house mouse (aka mus musculus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: peromyscus
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | [B] |
<Instruct>: Given the context 'We made similar observations in 2 month-old mice (data not shown) confirming earlier published results [21]).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mouse (aka mus musculus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus <genus> (mice (aka mus <genus>))
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [A] |
<Instruct>: Given the context 'These data from Ngn2+/GFP mice are entirely consistent with our earlier observations using immunocytochemistry to label Ngn2-expressing cells and with GFP undergoing slow degradation after the expression of Ngn2 has ceased.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus (aka mus <subgenus>) (aka mus <subgenus>)
B: mus (aka mus <genus>) (aka mus <genus>)
C: mus sp. (mice (aka mus sp.))
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: mouse (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Marked reduction of hippocampal granule neurons in absence of Ngn2
To determine the role of Ngn2 during the initiation of hippocampal granule neurogenesis, we analyzed the hippocampus of mice lacking Ngn2 (Ngn2GFP/GFP).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus sp. (mice (aka mus sp.))
B: mouse (aka mus <genus>)
C: mus castaneus (aka mus musculus castaneus)
D: mus musculus (house mouse) (aka mus musculus)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | [D] |
<Instruct>: Given the context 'In contrast to the mice use by Galichet and coworkers, our mice have a lifespan of only 2 weeks after birth.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: house mouse (aka mus musculus)
C: mice (aka mus sp.) (aka mus sp.)
D: mus domesticus (aka mus musculus domesticus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | [B] |
<Instruct>: Given the context 'Therefore, we analyzed 2 week-old and younger mice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mouse (aka mus <genus>)
B: mus sp. (mice (aka mus sp.))
C: mus cricetus (aka cricetus cricetus)
D: eastern european house mouse (aka mus musculus musculus)
E: mouse (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Therefore, we analyzed 2 week-old and younger mice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: eastern european house mouse (aka mus musculus musculus)
B: mouse (aka mus <genus>)
C: mus cricetus (aka cricetus cricetus)
D: mus sp. (mice (aka mus sp.))
E: None of the above. | [E] |
<Instruct>: Given the context 'In two week-old Ngn2GFP/GFP mice, the ventral blade of the DG is completely absent.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: mus castaneus (aka mus musculus castaneus)
C: mouse (aka mus musculus)
D: eastern european house mouse (aka mus musculus musculus)
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | [C] |
<Instruct>: Given the context 'As neither migration defects nor cell death cause the reduced number of hippocampal neurons in Ngn2 null mice [20], we asked if Ngn2 is necessary for production of hippocampal granule neuroblasts.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mice (aka mus sp.) (aka mus sp.)
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: house mouse (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'We first injected 2 day-old mouse pups with BrdU 2 hours prior to sacrifice, allowing us to evaluate cell proliferation and ongoing neurogenesis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse]
<Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: peromyscus
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: mus musculus (house mouse) (aka mus musculus)
E: mus <genus> (mice (aka mus <genus>))
F: None of the above. | [D] |
<Instruct>: Given the context 'We also injected BrdU into female mice on their final day of pregnancy and examined the brains of their pups 48 hours later (corresponding to P1–P2 old pups).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus sp. (mice (aka mus sp.))
B: mus castaneus (aka mus musculus castaneus)
C: peromyscus
D: mouse (aka mus musculus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | [D] |
<Instruct>: Given the context 'Regardless of whether the mice were WT or hetero/homozygous mutant pups, we found cells that had incorporated BrdU in the hippocampal subventricular zone (hSVZ), fimbria and the DG (Figure 4A and B; [28]), suggesting that progenitors originating in the hSVZ divide while migrating towards the DG.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: house mouse (aka mus musculus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: peromyscus
D: mus sp. (mice (aka mus sp.))
E: eastern european house mouse (aka mus musculus musculus)
F: None of the above. | [A] |
<Instruct>: Given the context 'In Ngn2GFP/GFP mutant mice injected with BrdU 2 hours prior to sacrifice, we observed a decrease in the number of BrdU+ cells compared to heterozygous littermates.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus domesticus (aka mus musculus domesticus)
B: house mouse (aka mus musculus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: peromyscus
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | [B] |
<Instruct>: Given the context 'We obtained similar results in the second paradigm, i.e. in mice that we sacrificed 48 hours after BrdU administration and in which a larger number of the newborn cells had time to mature into neurons.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: house mouse (aka mus musculus)
B: eastern european house mouse (aka mus musculus musculus)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: mus (aka mus <genus>) (aka mus <genus>)
E: peromyscus
F: None of the above. | [A] |
<Instruct>: Given the context 'We found no differences in the proportion of BrdU+ cells that expressed NeuroD1 in Ngn2+/GFP and Ngn2GFP/GFP mice (14.2±1.0% and 17.4±1.8% respectively; Figure 4K).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: mus <subgenus> (mus (aka mus <subgenus>))
C: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
D: mus sp. (mice (aka mus sp.))
E: house mouse (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'This shows that the few cells that manage to proliferate in the Ngn2 null mice have the same ability to differentiate into neurons as those in mice with one Ngn2 allele.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus domesticus (aka mus musculus domesticus)
B: mus cricetus (aka cricetus cricetus)
C: mus castaneus (aka mus musculus castaneus)
D: mouse (aka mus musculus)
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | [D] |
<Instruct>: Given the context 'Interestingly, the absence of Ngn2 did not alter the identity of neurons in the DG granule layer in 2 week-old Ngn2 null mice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus domesticus (aka mus musculus domesticus)
B: mice (aka mus <genus>) (aka mus <genus>)
C: mus cricetus (aka cricetus cricetus)
D: peromyscus
E: house mouse (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Interestingly, the absence of Ngn2 did not alter the identity of neurons in the DG granule layer in 2 week-old Ngn2 null mice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: peromyscus
B: mus cricetus (aka cricetus cricetus)
C: mus domesticus (aka mus musculus domesticus)
D: mice (aka mus <genus>) (aka mus <genus>)
E: None of the above. | [E] |
<Instruct>: Given the context 'We confirmed that the same transcriptional cascade is active in the 20% (compared to mice with one Ngn2 allele) residual granule neurons that are formed two day-old in Ngn2GFP/GFP mice (Figure S3D–G and data not shown).
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: house mouse (aka mus musculus)
C: eastern european house mouse (aka mus musculus musculus)
D: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | [B] |
<Instruct>: Given the context 'We next investigated if the cells that failed to develop into neurons in Ngn2GFP/GFP mutant mice, became glial cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: peromyscus
C: mus <subgenus> (mus (aka mus <subgenus>))
D: mus musculus (house mouse) (aka mus musculus)
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | [D] |
<Instruct>: Given the context 'We next monitored the mitogenic activity of Ngn2+ cells in the DG of 2 week-old WT mice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: eastern european house mouse (aka mus musculus musculus)
B: mus castaneus (aka mus musculus castaneus)
C: mouse (aka mus musculus)
D: mus (aka mus <genus>) (aka mus <genus>)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | [C] |
<Instruct>: Given the context 'We observed that over 50% of Ngn2+ cells in the DG of WT mice co-expressed the mitosis marker Ki67 (Figure 5A).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus <genus> (mice (aka mus <genus>))
B: mus castaneus (aka mus musculus castaneus)
C: mus musculus (house mouse) (aka mus musculus)
D: peromyscus
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | [C] |
<Instruct>: Given the context 'Inspired by this finding, we injected BrdU into 2 week-old WT and Ngn2GFP/GFP mice and compared cell proliferation in the DG.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus sp. (mice (aka mus sp.))
B: mouse (aka mus musculus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | [B] |
<Instruct>: Given the context 'We observed 92% reduction in number of proliferating cells in the SGZ of Ngn2 null mutant mice (6.7±0.5) compared to WT (83.6±1.2) and heterozygotic (data not shown) littermates (Figure 5B–C).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus domesticus (aka mus musculus domesticus)
B: peromyscus
C: house mouse (aka mus musculus)
D: mus <subgenus> (mus (aka mus <subgenus>))
E: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
F: None of the above. | [C] |
<Instruct>: Given the context 'To further explore whether Ngn2+ cells become post-mitotic or still proliferate after Ngn2 is downregulated, we performed immunohistochemistry on sections through the DG of Ngn2+/GFP mice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: peromyscus
C: mus castaneus (aka mus musculus castaneus)
D: mouse (aka mus musculus)
E: mus domesticus (aka mus musculus domesticus)
F: None of the above. | [D] |
<Instruct>: Given the context 'In mice lacking Ngn2, we found the cells expressing GFP localized to the malformed ventral blade of the DG (Figure 5F and G).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: mus musculus (house mouse) (aka mus musculus)
C: mus <genus> (mice (aka mus <genus>))
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: peromyscus
F: None of the above. | [B] |
<Instruct>: Given the context '[33] or NeuroD1, and the reporter gene eGFP into the ventricles E15.5 rat embryos, in utero (Figure 7A).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rat]
<Options>: A: rats (aka rattus sp.) (aka rattus sp.)
B: rattus (rats (aka rattus))
C: rat (aka rattus norvegicus) (aka rattus norvegicus)
D: rattus norvegicus albus
E: rattus rattoides (aka rattus rattus)
F: None of the above. | [C] |
<Instruct>: Given the context 'Three weeks later, when the rats were about two weeks old, we examined their hippocampi and analyzed the eGFP+ cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rats]
<Options>: A: brown rat (aka rattus norvegicus)
B: roof rat (aka rattus rattus)
C: rats (aka rattus sp.) (aka rattus sp.)
D: rattus (rats (aka rattus))
E: rattus norvegicus albus
F: None of the above. | [A] |
<Instruct>: Given the context 'Three weeks later, when the rats were about two weeks old, we examined their hippocampi and analyzed the eGFP+ cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rats]
<Options>: A: rattus norvegicus albus
B: rattus (rats (aka rattus))
C: rats (aka rattus sp.) (aka rattus sp.)
D: roof rat (aka rattus rattus)
E: None of the above. | [E] |
<Instruct>: Given the context 'The rats injected with control vector exhibited eGFP+ cells within the hippocampus that were either star-shaped, progenitor/glial-like cells (14.8±3.4%) or neuron-like cells with long neurites (85.3±3.4%)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rats]
<Options>: A: rats (aka rattus sp.) (aka rattus sp.)
B: rattus norvegicus albus
C: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
D: rattus norvegicus (rats (aka rattus norvegicus))
E: black rat (aka rattus rattus)
F: None of the above. | [D] |
<Instruct>: Given the context 'In rats that we had injected with the vector encoding Ngn2, the eGFP-labeled, the transduced hippocampal cells were composed of 31.9% (±5.7%) progenitor/glia-like cells and 69.4% (±6.1%) neuron-like cells (Figure 7B).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rats]
<Options>: A: rattus norvegicus albus
B: rattus (rats (aka rattus))
C: rattus rattoides (aka rattus pyctoris)
D: rat (aka rattus norvegicus) (aka rattus norvegicus)
E: rats (aka rattus sp.) (aka rattus sp.)
F: None of the above. | [D] |
<Instruct>: Given the context 'In contrast, virtually all of the transduced cells in rats injected with the NeuroD1 vector became neuron-like cells (99.9%±0.1; Figure 7B).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rats]
<Options>: A: rattus norvegicus (rats (aka rattus norvegicus))
B: rattus norvegicus albus
C: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
D: rats (aka rattus) (aka rattus)
E: roof rat (aka rattus rattus)
F: None of the above. | [A] |
<Instruct>: Given the context 'Indeed, when we overexpressed Ngn2 the proportion of hippocampal progenitors that became NeuN+ was no greater than in rats transduced with the control virus (Figure 7F).
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rats]
<Options>: A: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
B: rats (aka rattus sp.) (aka rattus sp.)
C: mus rattus (aka rattus rattus)
D: rat (aka rattus) (aka rattus)
E: brown rat (aka rattus norvegicus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Involvement of Mash1, Ngn2, Tbr and NeuroD proteins during human hippocampal neurogenesis
Finally, we examined whether the transcription factors and cellular markers that are expressed in rodents are also expressed in human hippocampus.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: mammals (aka mammalia)
B: macrobiotus sapiens
C: biota (aka cellular organisms)
D: primate (aka primates)
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'We performed immunohistochemistry on aged human hippocampal DG and found GFAP-, Sox2-, Pax6-, Nestin-, Prox1- and NeuN-immunopositive cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: human (aka homo sapiens)
B: humans (aka homo)
C: macrobiotus sapiens
D: primate (aka primates)
E: kingdom
F: None of the above. | [A] |
<Instruct>: Given the context 'This indicates that radial glia-like stem cells, neural progenitors and mature granule neurons are present in the aged human hippocampus (Figure 8A–E).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: cellular organisms (biota) (aka cellular organisms)
B: probles
C: animals (aka metazoa)
D: primate (aka primates)
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'As for aged rodents, we did not observe the presence of Mash1, Ngn2, Tbr2, Tbr1 and NeuroD1 proteins in aged human hippocampus, using immunohistochemistry.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: suborder
C: this
D: probles
E: eutherian mammals (aka eutheria)
F: None of the above. | [A] |
<Instruct>: Given the context 'Interestingly, we also observed Sonic Hedgehog and Wnt-3A transcripts, indicating that they are present in the human DG and supporting previous claims that they are important for the regulation of adult hippocampal neurogenesis (Figure 8F;', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: animals (aka metazoa)
B: kingdom
C: macrobiotus sapiens
D: this
E: human (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'Finally, we also found mRNA for GLAST, Pax6 and GFAP which suggests that radial glia-like stem cells are present in the adult human hippocampus, and may play a role in adult human hippocampal neurogenesis (Figure 8F;', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: homo (humans) (aka homo)
B: homo sapiens (human) (aka homo sapiens)
C: primate (aka primates)
D: species
E: kingdom
F: None of the above. | [B] |
<Instruct>: Given the context 'Finally, we also found mRNA for GLAST, Pax6 and GFAP which suggests that radial glia-like stem cells are present in the adult human hippocampus, and may play a role in adult human hippocampal neurogenesis (Figure 8F;', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: species
B: kingdom
C: primate (aka primates)
D: homo (humans) (aka homo)
E: None of the above. | [E] |
<Instruct>: Given the context 'Overall, our data show that different proteins known to play key roles in rodent hippocampal granule neurogenesis are present in the adult human hippocampus.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rodent; human]
<Options>: A: suborder
B: rodentia (rodents) (aka rodentia)
C: mammals (aka mammalia)
D: homo sapiens (human) (aka homo sapiens)
E: this
F: mus norvegicus (aka rattus norvegicus)
G: genus
H: mus (aka mus <subgenus>) (aka mus <subgenus>)
I: mus domesticus (aka mus musculus domesticus)
J: eutherian mammals (aka eutheria)
K: None of the above. | [B; D] |
<Instruct>: Given the context 'Overall, our data show that different proteins known to play key roles in rodent hippocampal granule neurogenesis are present in the adult human hippocampus.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rodent; human]
<Options>: A: mus <subgenus> (mus (aka mus <subgenus>))
B: house mouse (aka mus musculus)
C: macrobiotus sapiens
D: rodentia (rodents) (aka rodentia)
E: mus domesticus (aka mus musculus domesticus)
F: placental mammals (aka eutheria)
G: homo (humans) (aka homo)
H: mammals (aka mammalia)
I: kingdom
J: homo sapiens (human) (aka homo sapiens)
K: None of the above. | [D; J] |
<Instruct>: Given the context 'Finally, we show that different cellular markers expressed during hippocampal neurogenesis in rodents are present in human.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: species
B: this
C: placental mammals (aka eutheria)
D: macrobiotus sapiens
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'Mash1 null mutant mice do not display any clear malformation of the DG [20].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: peromyscus
B: mus (aka mus <genus>) (aka mus <genus>)
C: mouse (aka mus musculus)
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [C] |
<Instruct>: Given the context 'This applies both to the juvenile and adult rat brain [21], [25].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rat]
<Options>: A: norway rat (aka rattus norvegicus)
B: rat (aka rattus) (aka rattus)
C: rattus sp. (rats (aka rattus sp.))
D: rattus norvegicus albus
E: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
F: None of the above. | [A] |
<Instruct>: Given the context 'We found the sequential expression of these markers conserved in juvenile (P2 and 2 weeks) and adult rodent brains.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rodent]
<Options>: A: human (aka homo sapiens)
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mice (aka mus <genus>) (aka mus <genus>)
D: rodentia (rodents) (aka rodentia)
E: mus domesticus (aka mus musculus domesticus)
F: None of the above. | [D] |
<Instruct>: Given the context 'Importantly, we observed that the same transcription factors and neuronal markers are also present in the adult human hippocampus and arranged spatially in a manner reminiscent with what we saw in rodents.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: avian (aka aves)
B: species
C: homo sapiens (human) (aka homo sapiens)
D: suborder
E: this
F: None of the above. | [C] |
<Instruct>: Given the context 'Typically some mitotically active eGFP+ cells were present in the DG of rats injected with the Ngn2 retrovirus (Figure 7P), and we observed that cultured Ngn2-transduced cells are still capable of dividing.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rats]
<Options>: A: rat (aka rattus norvegicus) (aka rattus norvegicus)
B: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
C: rat (aka rattus) (aka rattus)
D: rattus norvegicus albus
E: rattus sp. (rats (aka rattus sp.))
F: None of the above. | [A] |
<Instruct>: Given the context 'Typically some mitotically active eGFP+ cells were present in the DG of rats injected with the Ngn2 retrovirus (Figure 7P), and we observed that cultured Ngn2-transduced cells are still capable of dividing.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rats]
<Options>: A: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
B: rattus norvegicus albus
C: rattus sp. (rats (aka rattus sp.))
D: rat (aka rattus) (aka rattus)
E: None of the above. | [E] |
<Instruct>: Given the context 'Because neuronal differentiation still occurs in Ngn2 null mice, it is clear that compensatory, Ngn2-independent mechanisms induce NeuroD1 expression.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus (aka mus <subgenus>) (aka mus <subgenus>)
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mus musculus (house mouse) (aka mus musculus)
D: mus castaneus (aka mus musculus castaneus)
E: peromyscus
F: None of the above. | [C] |
<Instruct>: Given the context 'One candidate is Ngn1, which is expressed during neocorticogenesis, the specification of olfactory sensory neurons and during embryonic rat hippocampal development', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rat]
<Options>: A: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
B: mus norvegicus (aka rattus norvegicus)
C: rattus sp. (rats (aka rattus sp.))
D: rat (aka rattus) (aka rattus)
E: rattus rattoides (aka rattus rattus)
F: None of the above. | [B] |
<Instruct>: Given the context 'The double null Ngn1/Ngn2 mutant displays a more severe phenotype than single gene (Ngn1 or Ngn2) mutant mice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: mus <subgenus> (mus (aka mus <subgenus>))
C: mus musculus (house mouse) (aka mus musculus)
D: mus sp. (mice (aka mus sp.))
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [C] |
<Instruct>: Given the context 'If the role of Ngn1 during hippocampal neurogenesis is to activate NeuroD1 and that of Ngn2 is to control granule neuroblasts production/amplification, the DG of double Ngn1/Ngn2 knockout mice should resemble that of NeuroD1 null mutant mice.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
B: mus sp. (mice (aka mus sp.))
C: mouse (aka mus musculus)
D: mus castaneus (aka mus musculus castaneus)
E: mouse (aka mus <genus>)
F: None of the above. | [C] |
<Instruct>: Given the context 'Materials and Methods
Animal tissue preparation
The creation of the Ngn2 transgenic mice was reported elsewhere (ref guillemot).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: mouse (aka mus <genus>)
C: house mouse (aka mus musculus)
D: mice (aka mus sp.) (aka mus sp.)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [C] |
<Instruct>: Given the context 'Heterozygote male and female mice were crossed to obtain WT, heterozygote (Ngn2+/GFP) and null mutant (Ngn2GFP/GFP) animals.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus domesticus (aka mus musculus domesticus)
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mus castaneus (aka mus musculus castaneus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Neurogenesis was assessed in two weeks or two months old WT mice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus castaneus (aka mus musculus castaneus)
B: mouse (aka mus musculus)
C: eastern european house mouse (aka mus musculus musculus)
D: mus sp. (mice (aka mus sp.))
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | [B] |
<Instruct>: Given the context 'Sprague Dawley pregnant rats were ordered from B&K Universal Ltd, Sollentuna, Sweden (hppt://www.bku.com).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rats]
<Options>: A: rattus norvegicus albus
B: rat (aka rattus norvegicus) (aka rattus norvegicus)
C: rats (aka rattus sp.) (aka rattus sp.)
D: mus rattus (aka rattus rattus)
E: rat (aka rattus) (aka rattus)
F: None of the above. | [B] |
<Instruct>: Given the context 'For immunohistochemical analysis, mice (from two weeks old and adult stage) and juvenile rats were sacrificed by transcardial perfusion with saline for 5–10 minutes, followed by 4% paraformaldehyde (PFA) for 10 minutes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice; rats]
<Options>: A: peromyscus
B: black rat (aka rattus rattus)
C: mus castaneus (aka mus musculus castaneus)
D: house mouse (aka mus musculus)
E: rattus rattoides (aka rattus pyctoris)
F: rattus norvegicus albus
G: mus sp. (mice (aka mus sp.))
H: rattus norvegicus (rats (aka rattus norvegicus))
I: mus <genus> (mice (aka mus <genus>))
J: rats (aka rattus sp.) (aka rattus sp.)
K: None of the above. | [D; H] |
<Instruct>: Given the context 'For immunohistochemical analysis, mice (from two weeks old and adult stage) and juvenile rats were sacrificed by transcardial perfusion with saline for 5–10 minutes, followed by 4% paraformaldehyde (PFA) for 10 minutes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice; rats]
<Options>: A: mus sp. (mice (aka mus sp.))
B: rattus norvegicus albus
C: peromyscus
D: mus <genus> (mice (aka mus <genus>))
E: mus castaneus (aka mus musculus castaneus)
F: black rat (aka rattus rattus)
G: house mouse (aka mus musculus)
H: rats (aka rattus sp.) (aka rattus sp.)
I: rattus rattoides (aka rattus pyctoris)
J: None of the above. | [G; J] |
<Instruct>: Given the context 'For immunohistochemical analysis, mice (from two weeks old and adult stage) and juvenile rats were sacrificed by transcardial perfusion with saline for 5–10 minutes, followed by 4% paraformaldehyde (PFA) for 10 minutes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice; rats]
<Options>: A: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
B: rattus (rats (aka rattus))
C: mus norvegicus (aka rattus norvegicus)
D: mus castaneus (aka mus musculus castaneus)
E: mice (aka mus sp.) (aka mus sp.)
F: rattus sp. (rats (aka rattus sp.))
G: peromyscus
H: rattus norvegicus albus
I: mus musculus (house mouse) (aka mus musculus)
J: eastern european house mouse (aka mus musculus musculus)
K: None of the above. | [I; C] |
<Instruct>: Given the context 'Heads of postanatal two days old mice were decapitated and soaked in PFA 4% for 24 hours, at 4°C and transferred into sucrose solution until sectioning on cryostat apparatus (16 µm thickness; Leica CM3000).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus (aka mus <subgenus>) (aka mus <subgenus>)
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: western european house mouse (aka mus musculus domesticus)
D: mouse (aka mus musculus)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | [D] |
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