instruction stringlengths 225 2.35k | input stringlengths 89 1.5k | response stringclasses 698 values |
|---|---|---|
<Instruct>: Given the context 'To generate the construct pCMMP-NeuroD1-IRES2eGFP-WPRE, mouse NeuroD1 cDNA was amplified from a pCS2+mtNeuroD1 plasmid (kindly provided by Professor Jackie Lee, Denver university, Boulder, USA) by PCR to introduce the restriction sites PmeI in 5′ and XhoI in 3′. Amplification of cDNA was performed as previously described [49].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse]
<Options>: A: western european house mouse (aka mus musculus domesticus)
B: mouse (aka mus musculus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus sp. (mice (aka mus sp.))
F: None of the above. | [B] |
<Instruct>: Given the context 'Neurosphere generation, transduction and differentiation
Pregnant female Sprague-Dawley rats (B & K Universal, Sollentuna, Sweden) were terminally anesthetized by an overdose of sodium pentobarbital (i.p., 60 ng/ml).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sprague-dawley rats]
<Options>: A: rats (aka rattus) (aka rattus)
B: rattus rattus kandianus
C: brown rat (aka rattus norvegicus)
D: polynesian rat (aka rattus exulans)
E: house rat (aka rattus rattus)
F: None of the above. | [C] |
<Instruct>: Given the context 'The antibodies used in this study are: rabbit anti-GFAP (1∶1000; DAKO), mouse anti-Nestin (1∶100; BD PharMingen), guinea pig anti-Glast (1∶500; Chemicon), rabbit anti-Prox1 (1∶1000; Covance), goat anti-Ngn2 (1∶20; Santa Cruz), goat anti-NeuroD1 (1∶200; Santa Cruz), rabbit anti-Pax6 (1∶150; Covance), rabbit anti-Trb2 (1∶500; Chemicon), rabbit anti-Trb1: (1∶1000; Chemicon), goat anti-Dcx: (1∶500; Santa Cruz), mouse anti-PSA-NCAM: (1∶500; Chemicon), mouse anti-NeuN (1∶300; Chemicon), rabbit anti-Calretinin (1∶500; Swant); mouse anti-Sox2 (1∶100; R&D systems), mouse anti-Mash1 (1∶100; BD PharMingen), rabbit anti-NeuroD2 (1∶300; ABCAM), mouse anti-MAP2 (1∶500; Sigma), rabbit anti-Ki67 (1∶150; NovaCastra) and rabbit anti-phospho-Histone H3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbit; mouse; guinea pig]
<Options>: A: peromyscus
B: cavia porcellus (cavia aperea porcellus) (aka cavia porcellus)
C: western european house mouse (aka mus musculus domesticus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: japanese white rabbit (aka oryctolagus cuniculus)
F: brazilian guinea pig (aka cavia aperea)
G: house mouse (aka mus musculus)
H: guineafowls (aka numididae)
I: ox (aka bos taurus) (aka bos taurus)
J: cattle (aka bos)
K: mice (aka mus <genus>) (aka mus <genus>)
L: european hare (aka lepus europaeus)
M: caviidae (cavies) (aka caviidae)
N: chickens (aka gallus gallus)
O: bovidae
P: None of the above. | [E; G; B] |
<Instruct>: Given the context 'The antibodies used in this study are: rabbit anti-GFAP (1∶1000; DAKO), mouse anti-Nestin (1∶100; BD PharMingen), guinea pig anti-Glast (1∶500; Chemicon), rabbit anti-Prox1 (1∶1000; Covance), goat anti-Ngn2 (1∶20; Santa Cruz), goat anti-NeuroD1 (1∶200; Santa Cruz), rabbit anti-Pax6 (1∶150; Covance), rabbit anti-Trb2 (1∶500; Chemicon), rabbit anti-Trb1: (1∶1000; Chemicon), goat anti-Dcx: (1∶500; Santa Cruz), mouse anti-PSA-NCAM: (1∶500; Chemicon), mouse anti-NeuN (1∶300; Chemicon), rabbit anti-Calretinin (1∶500; Swant); mouse anti-Sox2 (1∶100; R&D systems), mouse anti-Mash1 (1∶100; BD PharMingen), rabbit anti-NeuroD2 (1∶300; ABCAM), mouse anti-MAP2 (1∶500; Sigma), rabbit anti-Ki67 (1∶150; NovaCastra) and rabbit anti-phospho-Histone H3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbit; mouse; guinea pig]
<Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus domesticus (aka mus musculus domesticus)
C: marsh rabbit (aka sylvilagus palustris)
D: domestic guinea pig (aka cavia porcellus)
E: mus cricetus (aka cricetus cricetus)
F: domestic rabbit (aka oryctolagus cuniculus)
G: brazilian guinea pig (aka cavia aperea)
H: hares (aka lepus)
I: guinea-pigs (aka cavia)
J: chickens (aka gallus gallus)
K: mus sp. (mice (aka mus sp.))
L: swamp rabbit (aka sylvilagus aquaticus)
M: lepus cuniculus cuniculus (aka oryctolagus cuniculus cuniculus)
N: peromyscus
O: cavies (aka caviidae)
P: None of the above. | [F; A; D] |
<Instruct>: Given the context 'The antibodies used in this study are: rabbit anti-GFAP (1∶1000; DAKO), mouse anti-Nestin (1∶100; BD PharMingen), guinea pig anti-Glast (1∶500; Chemicon), rabbit anti-Prox1 (1∶1000; Covance), goat anti-Ngn2 (1∶20; Santa Cruz), goat anti-NeuroD1 (1∶200; Santa Cruz), rabbit anti-Pax6 (1∶150; Covance), rabbit anti-Trb2 (1∶500; Chemicon), rabbit anti-Trb1: (1∶1000; Chemicon), goat anti-Dcx: (1∶500; Santa Cruz), mouse anti-PSA-NCAM: (1∶500; Chemicon), mouse anti-NeuN (1∶300; Chemicon), rabbit anti-Calretinin (1∶500; Swant); mouse anti-Sox2 (1∶100; R&D systems), mouse anti-Mash1 (1∶100; BD PharMingen), rabbit anti-NeuroD2 (1∶300; ABCAM), mouse anti-MAP2 (1∶500; Sigma), rabbit anti-Ki67 (1∶150; NovaCastra) and rabbit anti-phospho-Histone H3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbit; mouse; guinea pig]
<Options>: A: cavia magna (greater guinea pig) (aka cavia magna)
B: caviidae (cavies) (aka caviidae)
C: lepus europaeus europaeus
D: cavia (guinea pigs) (aka cavia)
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: mus musculus (house mouse) (aka mus musculus)
G: ox (aka bos taurus) (aka bos taurus)
H: peromyscus
I: domestic rabbit (aka oryctolagus cuniculus)
J: cattle (aka bos)
K: guinea pig (aka cavia porcellus)
L: swamp rabbit (aka sylvilagus aquaticus)
M: mus cricetus (aka cricetus cricetus)
N: mouse (aka mus <genus>)
O: cavia fulgida (shiny guinea pig) (aka cavia fulgida)
P: None of the above. | [I; F; K] |
<Instruct>: Given the context 'The antibodies used in this study are: rabbit anti-GFAP (1∶1000; DAKO), mouse anti-Nestin (1∶100; BD PharMingen), guinea pig anti-Glast (1∶500; Chemicon), rabbit anti-Prox1 (1∶1000; Covance), goat anti-Ngn2 (1∶20; Santa Cruz), goat anti-NeuroD1 (1∶200; Santa Cruz), rabbit anti-Pax6 (1∶150; Covance), rabbit anti-Trb2 (1∶500; Chemicon), rabbit anti-Trb1: (1∶1000; Chemicon), goat anti-Dcx: (1∶500; Santa Cruz), mouse anti-PSA-NCAM: (1∶500; Chemicon), mouse anti-NeuN (1∶300; Chemicon), rabbit anti-Calretinin (1∶500; Swant); mouse anti-Sox2 (1∶100; R&D systems), mouse anti-Mash1 (1∶100; BD PharMingen), rabbit anti-NeuroD2 (1∶300; ABCAM), mouse anti-MAP2 (1∶500; Sigma), rabbit anti-Ki67 (1∶150; NovaCastra) and rabbit anti-phospho-Histone H3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [goat; rabbit]
<Options>: A: cattle (aka bos)
B: donkey (aka equus asinus)
C: capreolus
D: swamp rabbit (aka sylvilagus aquaticus)
E: sueus
F: rabbit (aka oryctolagus cuniculus)
G: goats (aka capra hircus)
H: oryctolagus cuniculus cuniculus (lepus cuniculus cuniculus) (aka oryctolagus cuniculus cuniculus)
I: bovidae
J: None of the above. | [G; F] |
<Instruct>: Given the context 'The antibodies used in this study are: rabbit anti-GFAP (1∶1000; DAKO), mouse anti-Nestin (1∶100; BD PharMingen), guinea pig anti-Glast (1∶500; Chemicon), rabbit anti-Prox1 (1∶1000; Covance), goat anti-Ngn2 (1∶20; Santa Cruz), goat anti-NeuroD1 (1∶200; Santa Cruz), rabbit anti-Pax6 (1∶150; Covance), rabbit anti-Trb2 (1∶500; Chemicon), rabbit anti-Trb1: (1∶1000; Chemicon), goat anti-Dcx: (1∶500; Santa Cruz), mouse anti-PSA-NCAM: (1∶500; Chemicon), mouse anti-NeuN (1∶300; Chemicon), rabbit anti-Calretinin (1∶500; Swant); mouse anti-Sox2 (1∶100; R&D systems), mouse anti-Mash1 (1∶100; BD PharMingen), rabbit anti-NeuroD2 (1∶300; ABCAM), mouse anti-MAP2 (1∶500; Sigma), rabbit anti-Ki67 (1∶150; NovaCastra) and rabbit anti-phospho-Histone H3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [goat; rabbit]
<Options>: A: bovidae
B: lepus europaeus europaeus
C: capra hircus cretica (capra aegagrus cretica) (aka capra hircus cretica)
D: donkey (aka equus asinus)
E: capreolus
F: hares (aka lepus)
G: ox (aka bos taurus) (aka bos taurus)
H: european rabbit (aka oryctolagus cuniculus)
I: capraita
J: capra hircus (capra aegagrus hircus) (aka capra hircus)
K: None of the above. | [J; H] |
<Instruct>: Given the context 'The antibodies used in this study are: rabbit anti-GFAP (1∶1000; DAKO), mouse anti-Nestin (1∶100; BD PharMingen), guinea pig anti-Glast (1∶500; Chemicon), rabbit anti-Prox1 (1∶1000; Covance), goat anti-Ngn2 (1∶20; Santa Cruz), goat anti-NeuroD1 (1∶200; Santa Cruz), rabbit anti-Pax6 (1∶150; Covance), rabbit anti-Trb2 (1∶500; Chemicon), rabbit anti-Trb1: (1∶1000; Chemicon), goat anti-Dcx: (1∶500; Santa Cruz), mouse anti-PSA-NCAM: (1∶500; Chemicon), mouse anti-NeuN (1∶300; Chemicon), rabbit anti-Calretinin (1∶500; Swant); mouse anti-Sox2 (1∶100; R&D systems), mouse anti-Mash1 (1∶100; BD PharMingen), rabbit anti-NeuroD2 (1∶300; ABCAM), mouse anti-MAP2 (1∶500; Sigma), rabbit anti-Ki67 (1∶150; NovaCastra) and rabbit anti-phospho-Histone H3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbit; goat; mouse]
<Options>: A: domestic goat (aka capra hircus)
B: mus (aka mus <genus>) (aka mus <genus>)
C: capra aegagrus cretica (aka capra hircus cretica)
D: rabbits (aka oryctolagus cuniculus)
E: mus cricetus (aka cricetus cricetus)
F: capra aegagrus (capra hircus aegagrus) (aka capra aegagrus)
G: bovidae
H: mus molossinus (aka mus musculus molossinus)
I: swamp rabbit (aka sylvilagus aquaticus)
J: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
K: marsh rabbit (aka sylvilagus palustris)
L: rabbits and hares (aka leporidae)
M: mus musculus (house mouse) (aka mus musculus)
N: capneidae
O: ox (aka bos taurus) (aka bos taurus)
P: None of the above. | [D; A; M] |
<Instruct>: Given the context 'The antibodies used in this study are: rabbit anti-GFAP (1∶1000; DAKO), mouse anti-Nestin (1∶100; BD PharMingen), guinea pig anti-Glast (1∶500; Chemicon), rabbit anti-Prox1 (1∶1000; Covance), goat anti-Ngn2 (1∶20; Santa Cruz), goat anti-NeuroD1 (1∶200; Santa Cruz), rabbit anti-Pax6 (1∶150; Covance), rabbit anti-Trb2 (1∶500; Chemicon), rabbit anti-Trb1: (1∶1000; Chemicon), goat anti-Dcx: (1∶500; Santa Cruz), mouse anti-PSA-NCAM: (1∶500; Chemicon), mouse anti-NeuN (1∶300; Chemicon), rabbit anti-Calretinin (1∶500; Swant); mouse anti-Sox2 (1∶100; R&D systems), mouse anti-Mash1 (1∶100; BD PharMingen), rabbit anti-NeuroD2 (1∶300; ABCAM), mouse anti-MAP2 (1∶500; Sigma), rabbit anti-Ki67 (1∶150; NovaCastra) and rabbit anti-phospho-Histone H3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbit; goat; mouse]
<Options>: A: house mouse (aka mus musculus)
B: capra hircus cretica (capra aegagrus cretica) (aka capra hircus cretica)
C: mus cricetus (aka cricetus cricetus)
D: swamp rabbit (aka sylvilagus aquaticus)
E: rabbit (aka oryctolagus cuniculus)
F: goats (aka capra hircus)
G: capraita
H: mus <subgenus> (mus (aka mus <subgenus>))
I: capra
J: bovidae
K: marsh rabbit (aka sylvilagus palustris)
L: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
M: peromyscus
N: hares (aka lepus)
O: None of the above. | [E; F; A] |
<Instruct>: Given the context 'The antibodies used in this study are: rabbit anti-GFAP (1∶1000; DAKO), mouse anti-Nestin (1∶100; BD PharMingen), guinea pig anti-Glast (1∶500; Chemicon), rabbit anti-Prox1 (1∶1000; Covance), goat anti-Ngn2 (1∶20; Santa Cruz), goat anti-NeuroD1 (1∶200; Santa Cruz), rabbit anti-Pax6 (1∶150; Covance), rabbit anti-Trb2 (1∶500; Chemicon), rabbit anti-Trb1: (1∶1000; Chemicon), goat anti-Dcx: (1∶500; Santa Cruz), mouse anti-PSA-NCAM: (1∶500; Chemicon), mouse anti-NeuN (1∶300; Chemicon), rabbit anti-Calretinin (1∶500; Swant); mouse anti-Sox2 (1∶100; R&D systems), mouse anti-Mash1 (1∶100; BD PharMingen), rabbit anti-NeuroD2 (1∶300; ABCAM), mouse anti-MAP2 (1∶500; Sigma), rabbit anti-Ki67 (1∶150; NovaCastra) and rabbit anti-phospho-Histone H3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbit; goat; mouse]
<Options>: A: mus <genus> (mice (aka mus <genus>))
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mus domesticus (aka mus musculus domesticus)
D: wild goat (aka capra aegagrus)
E: hares (aka lepus)
F: ox (aka bos taurus) (aka bos taurus)
G: japanese white rabbit (aka oryctolagus cuniculus)
H: lepus europaeus europaeus
I: cattle (aka bos)
J: sueus
K: goats (aka capra hircus)
L: mus <subgenus> (mus (aka mus <subgenus>))
M: european hare (aka lepus europaeus)
N: mouse (aka mus musculus)
O: capraita
P: None of the above. | [G; K; N] |
<Instruct>: Given the context 'The antibodies used in this study are: rabbit anti-GFAP (1∶1000; DAKO), mouse anti-Nestin (1∶100; BD PharMingen), guinea pig anti-Glast (1∶500; Chemicon), rabbit anti-Prox1 (1∶1000; Covance), goat anti-Ngn2 (1∶20; Santa Cruz), goat anti-NeuroD1 (1∶200; Santa Cruz), rabbit anti-Pax6 (1∶150; Covance), rabbit anti-Trb2 (1∶500; Chemicon), rabbit anti-Trb1: (1∶1000; Chemicon), goat anti-Dcx: (1∶500; Santa Cruz), mouse anti-PSA-NCAM: (1∶500; Chemicon), mouse anti-NeuN (1∶300; Chemicon), rabbit anti-Calretinin (1∶500; Swant); mouse anti-Sox2 (1∶100; R&D systems), mouse anti-Mash1 (1∶100; BD PharMingen), rabbit anti-NeuroD2 (1∶300; ABCAM), mouse anti-MAP2 (1∶500; Sigma), rabbit anti-Ki67 (1∶150; NovaCastra) and rabbit anti-phospho-Histone H3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbit; mouse]
<Options>: A: mus sp. (mice (aka mus sp.))
B: european hare (aka lepus europaeus)
C: hares (aka lepus)
D: mus musculus (house mouse) (aka mus musculus)
E: rabbits (aka oryctolagus cuniculus)
F: mus molossinus (aka mus musculus molossinus)
G: swamp rabbit (aka sylvilagus aquaticus)
H: mus (aka mus <subgenus>) (aka mus <subgenus>)
I: bovidae
J: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
K: None of the above. | [E; D] |
<Instruct>: Given the context 'The antibodies used in this study are: rabbit anti-GFAP (1∶1000; DAKO), mouse anti-Nestin (1∶100; BD PharMingen), guinea pig anti-Glast (1∶500; Chemicon), rabbit anti-Prox1 (1∶1000; Covance), goat anti-Ngn2 (1∶20; Santa Cruz), goat anti-NeuroD1 (1∶200; Santa Cruz), rabbit anti-Pax6 (1∶150; Covance), rabbit anti-Trb2 (1∶500; Chemicon), rabbit anti-Trb1: (1∶1000; Chemicon), goat anti-Dcx: (1∶500; Santa Cruz), mouse anti-PSA-NCAM: (1∶500; Chemicon), mouse anti-NeuN (1∶300; Chemicon), rabbit anti-Calretinin (1∶500; Swant); mouse anti-Sox2 (1∶100; R&D systems), mouse anti-Mash1 (1∶100; BD PharMingen), rabbit anti-NeuroD2 (1∶300; ABCAM), mouse anti-MAP2 (1∶500; Sigma), rabbit anti-Ki67 (1∶150; NovaCastra) and rabbit anti-phospho-Histone H3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbit; mouse]
<Options>: A: european hare (aka lepus europaeus)
B: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
C: mus molossinus (aka mus musculus molossinus)
D: mus musculus (house mouse) (aka mus musculus)
E: swamp rabbit (aka sylvilagus aquaticus)
F: cattle (aka bos)
G: lepus cuniculus (aka oryctolagus cuniculus)
H: mus (aka mus <subgenus>) (aka mus <subgenus>)
I: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
J: rabbits and hares (aka leporidae)
K: None of the above. | [G; D] |
<Instruct>: Given the context 'The antibodies used in this study are: rabbit anti-GFAP (1∶1000; DAKO), mouse anti-Nestin (1∶100; BD PharMingen), guinea pig anti-Glast (1∶500; Chemicon), rabbit anti-Prox1 (1∶1000; Covance), goat anti-Ngn2 (1∶20; Santa Cruz), goat anti-NeuroD1 (1∶200; Santa Cruz), rabbit anti-Pax6 (1∶150; Covance), rabbit anti-Trb2 (1∶500; Chemicon), rabbit anti-Trb1: (1∶1000; Chemicon), goat anti-Dcx: (1∶500; Santa Cruz), mouse anti-PSA-NCAM: (1∶500; Chemicon), mouse anti-NeuN (1∶300; Chemicon), rabbit anti-Calretinin (1∶500; Swant); mouse anti-Sox2 (1∶100; R&D systems), mouse anti-Mash1 (1∶100; BD PharMingen), rabbit anti-NeuroD2 (1∶300; ABCAM), mouse anti-MAP2 (1∶500; Sigma), rabbit anti-Ki67 (1∶150; NovaCastra) and rabbit anti-phospho-Histone H3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse; rabbit]
<Options>: A: rabbits (aka oryctolagus cuniculus)
B: mus musculus (house mouse) (aka mus musculus)
C: swamp rabbit (aka sylvilagus aquaticus)
D: mus molossinus (aka mus musculus molossinus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: mice (aka mus <genus>) (aka mus <genus>)
G: ox (aka bos taurus) (aka bos taurus)
H: mus sp. (mice (aka mus sp.))
I: lepus europaeus europaeus
J: cattle (aka bos)
K: None of the above. | [B; A] |
<Instruct>: Given the context 'The antibodies used in this study are: rabbit anti-GFAP (1∶1000; DAKO), mouse anti-Nestin (1∶100; BD PharMingen), guinea pig anti-Glast (1∶500; Chemicon), rabbit anti-Prox1 (1∶1000; Covance), goat anti-Ngn2 (1∶20; Santa Cruz), goat anti-NeuroD1 (1∶200; Santa Cruz), rabbit anti-Pax6 (1∶150; Covance), rabbit anti-Trb2 (1∶500; Chemicon), rabbit anti-Trb1: (1∶1000; Chemicon), goat anti-Dcx: (1∶500; Santa Cruz), mouse anti-PSA-NCAM: (1∶500; Chemicon), mouse anti-NeuN (1∶300; Chemicon), rabbit anti-Calretinin (1∶500; Swant); mouse anti-Sox2 (1∶100; R&D systems), mouse anti-Mash1 (1∶100; BD PharMingen), rabbit anti-NeuroD2 (1∶300; ABCAM), mouse anti-MAP2 (1∶500; Sigma), rabbit anti-Ki67 (1∶150; NovaCastra) and rabbit anti-phospho-Histone H3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse; rabbit]
<Options>: A: rabbits (aka oryctolagus cuniculus)
B: mus sp. (mice (aka mus sp.))
C: mus (aka mus <genus>) (aka mus <genus>)
D: ox (aka bos taurus) (aka bos taurus)
E: european hare (aka lepus europaeus)
F: mus cricetus (aka cricetus cricetus)
G: mouse (aka mus musculus)
H: lepus europaeus europaeus
I: eastern european house mouse (aka mus musculus musculus)
J: leporidae (rabbits and hares) (aka leporidae)
K: None of the above. | [G; A] |
<Instruct>: Given the context 'For immunocytochemistry, cultures were fixed in 4% paraformaldehyde at day five, rinsed with PBS three times prior to pre-incubation with a blocking solution (10% donkey serum, 0.25% TritonX100 in PBS) for 1 hour.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [donkey]
<Options>: A: domestic ass (aka equus asinus)
B: equus subg. asinus (aka equus)
C: equus asinus asinus
D: equus asinus x equus caballus (hybrid of male donkey and female horse) (aka equus asinus x equus caballus)
E: equus asinus africanus (equus africanus asinus) (aka equus asinus africanus)
F: None of the above. | [A] |
<Instruct>: Given the context 'Bromo-deoxyuridine (BrdU) and Cloro-deoxyuridine (CldU) pulse labeling and immunohisto- and immunocyto-chemistry
To assess cell proliferation and ongoing neurogenesis in vivo, animals were injected with BrdU (100 mg/kg, Sigma), two hours prior to sacrifice (for both P2 and two weeks old Ngn2 mice).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: peromyscus
C: mus musculus (house mouse) (aka mus musculus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | [C] |
<Instruct>: Given the context 'Immunohistochemistry was carried on as described above using a rat anti-CldU/BrdU primary antibody (1∶200, monoclonal, Immunologicalsdirect, Oxfordshire, UK), with an additional denaturation in 1 M HCl for 30 minutes prior to pre-incubation with serum.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rat]
<Options>: A: rattus rattoides (aka rattus rattus)
B: rat (aka rattus) (aka rattus)
C: rattus rattoides (aka rattus pyctoris)
D: rats (aka rattus sp.) (aka rattus sp.)
E: brown rat (aka rattus norvegicus)
F: None of the above. | [E] |
<Instruct>: Given the context 'For immunocytochemistry, cultures were fixed with 4% paraformaldehyde at day 7, rinsed with PBS three times, treated with 1 M HCl at 65°C for 5–10 min, pre-incubated and then incubated with a rat anti-CldU/BrdU antibody and other primary antibodies.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rat]
<Options>: A: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
B: rattus sp. (rats (aka rattus sp.))
C: rattus norvegicus albus
D: mus norvegicus (aka rattus norvegicus)
E: rat (aka rattus) (aka rattus)
F: None of the above. | [D] |
<Instruct>: Given the context 'In utero surgery
Timed pregnant female Sprague Dawley rats with embryos at gestational age E15.5 were anesthetized with halothane.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sprague dawley rats]
<Options>: A: rats (aka rattus) (aka rattus)
B: rats (aka rattus norvegicus) (aka rattus norvegicus)
C: rattus norvegicus albus
D: dusky field rat (aka rattus sordidus)
E: eastern new guinea rat (aka rattus mordax)
F: None of the above. | [B] |
<Instruct>: Given the context 'In utero surgery
Timed pregnant female Sprague Dawley rats with embryos at gestational age E15.5 were anesthetized with halothane.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sprague dawley rats]
<Options>: A: dusky field rat (aka rattus sordidus)
B: rattus norvegicus albus
C: rats (aka rattus) (aka rattus)
D: eastern new guinea rat (aka rattus mordax)
E: None of the above. | [E] |
<Instruct>: Given the context 'In this study, more than 25 Ngn2 null, >45 Ngn2 heterozygotes, and >60 WT individuals (including rats injected with retroviruses) were analyzed, in total.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rats]
<Options>: A: rats (aka rattus sp.) (aka rattus sp.)
B: rat (aka rattus) (aka rattus)
C: rats (aka rattus norvegicus) (aka rattus norvegicus)
D: black rat (aka rattus rattus)
E: rattus norvegicus albus
F: None of the above. | [C] |
<Instruct>: Given the context 'All data are expressed as±standard error of the mean (SEM).
Human sample and RT-PCR
The brain from a 64 year-old male was provided by the Harvard Brain Tissue Resource Center.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: human (aka homo sapiens)
B: eutherian mammals (aka eutheria)
C: animals (aka metazoa)
D: kingdom
E: macrobiotus sapiens
F: None of the above. | [A] |
<Instruct>: Given the context 'Five millimeters thick fresh human hippocampal tissue sample was snap frozen.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: cellular organisms (biota) (aka cellular organisms)
B: human (aka homo sapiens)
C: genus
D: primate (aka primates)
E: this
F: None of the above. | [B] |
<Instruct>: Given the context 'Some of them (but not the parent sulfonamides) strongly lowered IOP in rabbits when administered as a 2% solution into the eye.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbits]
<Options>: A: lepus europaeus europaeus
B: swamp rabbit (aka sylvilagus aquaticus)
C: japanese white rabbit (aka oryctolagus cuniculus)
D: bovidae
E: ox (aka bos taurus) (aka bos taurus)
F: None of the above. | [C] |
<Instruct>: Given the context 'Some of them (but not the parent sulfonamides) strongly lowered IOP in rabbits when administered as a 2% solution into the eye.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbits]
<Options>: A: oryctolagus cuniculus (japanese white rabbit) (aka oryctolagus cuniculus)
B: marsh rabbit (aka sylvilagus palustris)
C: rabbits and hares (aka leporidae)
D: bovidae
E: ox (aka bos taurus) (aka bos taurus)
F: None of the above. | [A] |
<Instruct>: Given the context 'The new compounds have been characterized by standard physico-chemical procedures, and were assayed as inhibitors of three CA isozymes, hCA I, hCA II and bCA IV (h human; b bovine; these are the isozymes considered to play a critical role in aqueous humour secretion within the eye of higher vertebrates [2-5]).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human; bovine]
<Options>: A: primate (aka primates)
B: homo sapiens (human) (aka homo sapiens)
C: bos sp.
D: cattle (aka bos)
E: bos indicus (bos primigenius indicus) (aka bos indicus)
F: dairy cow (aka bos taurus)
G: macrobiotus sapiens
H: bovidae
I: this
J: animals (aka metazoa)
K: None of the above. | [B; F] |
<Instruct>: Given the context 'The new compounds have been characterized by standard physico-chemical procedures, and were assayed as inhibitors of three CA isozymes, hCA I, hCA II and bCA IV (h human; b bovine; these are the isozymes considered to play a critical role in aqueous humour secretion within the eye of higher vertebrates [2-5]).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human; bovine]
<Options>: A: human (aka homo sapiens)
B: domestic cattle (aka bos taurus)
C: avian (aka aves)
D: bos taurus x bos indicus (aka bos indicus x bos taurus)
E: boveria
F: bovinae
G: bos taurus indicus (aka bos indicus)
H: humans (aka homo)
I: mammals (aka mammalia)
J: genus
K: None of the above. | [A; B] |
<Instruct>: Given the context 'Human CA and CA II cDNAs were expressed in Escherichia coli strain BL21 (DE3) from the plasmids pACA/hCA I and pACAdaCA II described by Forsman et al.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: avian (aka aves)
B: homo sapiens (human) (aka homo sapiens)
C: humans (aka homo)
D: primate (aka primates)
E: kingdom
F: None of the above. | [B] |
<Instruct>: Given the context 'Human CA and CA II cDNAs were expressed in Escherichia coli strain BL21 (DE3) from the plasmids pACA/hCA I and pACAdaCA II described by Forsman et al.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: kingdom
B: humans (aka homo)
C: avian (aka aves)
D: primate (aka primates)
E: None of the above. | [E] |
<Instruct>: Given the context 'IV was isolated from bovine lung microsomes as described by Maren et al, and its concentration has been determined by titration with ethoxzolamide [33].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bovine]
<Options>: A: bos sp.
B: domestic cattle (aka bos taurus)
C: boveria
D: bos bubalis bubalis (aka bubalus bubalis bubalis)
E: bovidae
F: None of the above. | [B] |
<Instruct>: Given the context 'Measurement of tonometric lOP Adult male New Zealand albino rabbits weighing 2-3 kg were used in the experiments (three animals were used for each inhibitor studied).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbits]
<Options>: A: rabbits (aka oryctolagus cuniculus)
B: hares (aka lepus)
C: lepus europaeus europaeus
D: bovidae
E: cattle (aka bos)
F: None of the above. | [A] |
<Instruct>: Given the context 'The rabbits were kept in individual cages with food and water provided ad libitum.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbits]
<Options>: A: rabbits (aka oryctolagus cuniculus)
B: marsh rabbit (aka sylvilagus palustris)
C: bovidae
D: oryctolagus cuniculus cuniculus (lepus cuniculus cuniculus) (aka oryctolagus cuniculus cuniculus)
E: cattle (aka bos)
F: None of the above. | [A] |
<Instruct>: Given the context 'The ocular hypotensive activity is expressed as the average difference in IOP between the treated and control eye, in this way minimizing the diurnal, seasonal and interindividual variations commonly observed in the rabbit [37-39].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbit]
<Options>: A: cattle (aka bos)
B: japanese white rabbit (aka oryctolagus cuniculus)
C: rabbits and hares (aka leporidae)
D: hares (aka lepus)
E: swamp rabbit (aka sylvilagus aquaticus)
F: None of the above. | [B] |
<Instruct>: Given the context 'In vivo IOP lowering experiments were done in rabbits with some of the new compounds prepared in the present work, such as the sulfonamides 6 and 7, and their Zn(II) complexes, which were among the strong CA II and CA IV inhibitors in the obtained series.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbits]
<Options>: A: rabbits (aka oryctolagus cuniculus)
B: lepus europaeus europaeus
C: lepus (hares) (aka lepus)
D: marsh rabbit (aka sylvilagus palustris)
E: bovidae
F: None of the above. | [A] |
<Instruct>: Given the context 'Some of the IOP lowering data at half an hour and one hour after the instillation of one drop of 2 % solution of inhibitor within the rabbit eye are shown in 312
Claudiu T. Supuran et al.
Metal-Based Drugs
Table IV, with dorzolamide (at the same concentration) as standard.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbit]
<Options>: A: rabbit (aka oryctolagus cuniculus)
B: bovidae
C: swamp rabbit (aka sylvilagus aquaticus)
D: lepus cuniculus cuniculus (aka oryctolagus cuniculus cuniculus)
E: cattle (aka bos)
F: None of the above. | [A] |
<Instruct>: Given the context 'Acetazolamide Methazolamide Ethoxzolamide
Dichlorophenamide Dorzolamide
Human (cloned) isozymes; b From bovine lung microsomes.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human; bovine]
<Options>: A: suborder
B: human (aka homo sapiens)
C: bovinae
D: macrobiotus sapiens
E: bovidae
F: this
G: cattle (aka bos)
H: kingdom
I: bos primigenius taurus (aka bos taurus)
J: bos indicus (bos primigenius indicus) (aka bos indicus)
K: None of the above. | [B; I] |
<Instruct>: Given the context 'Acetazolamide Methazolamide Ethoxzolamide
Dichlorophenamide Dorzolamide
Human (cloned) isozymes; b From bovine lung microsomes.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human; bovine]
<Options>: A: species
B: bos (cattle) (aka bos)
C: homo sapiens (human) (aka homo sapiens)
D: bos bubalis (aka bubalus bubalis)
E: suborder
F: bos taurus x bos indicus (aka bos indicus x bos taurus)
G: animals (aka metazoa)
H: genus
I: domestic cattle (aka bos taurus)
J: boveria
K: None of the above. | [C; I] |
<Instruct>: Given the context 'Acetazolamide Methazolamide Ethoxzolamide
Dichlorophenamide Dorzolamide
Human (cloned) isozymes; b From bovine lung microsomes.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human; bovine]
<Options>: A: species
B: genus
C: suborder
D: animals (aka metazoa)
E: boveria
F: bos bubalis (aka bubalus bubalis)
G: homo sapiens (human) (aka homo sapiens)
H: bos taurus x bos indicus (aka bos indicus x bos taurus)
I: bos (cattle) (aka bos)
J: None of the above. | [G; J] |
<Instruct>: Given the context 'Fig l" Time dependence of IOP lowering with dorzolamide (curve 1); the zinc complex 10 (curve 3) and the zinc complex 17 (curve 3), after topical administration of one drop of 2 % solution of inhibitor in rabbit.
Preliminary results from this laboratory indicate that the metal complexes of topically active sulfonamides show also increased lOP lowering effects with respect to the complexes prepared in the present study', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbit]
<Options>: A: domestic rabbit (aka oryctolagus cuniculus)
B: swamp rabbit (aka sylvilagus aquaticus)
C: ox (aka bos taurus) (aka bos taurus)
D: bovidae
E: cattle (aka bos)
F: None of the above. | [A] |
<Instruct>: Given the context 'Borrelia burgdorferi membranes are the primary targets of reactive oxygen species
Abstract
Spirochetes living in an oxygen-rich environment or when challenged by host immune cells are exposed to reactive oxygen species (ROS).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [borrelia burgdorferi]
<Options>: A: borrelia burgdorferi (aka borreliella burgdorferi)
B: borrelia fainii (aka candidatus borrelia fainii)
C: candidatus borrelia africana (borrelia africana) (aka candidatus borrelia africana)
D: borrelia genomosp. 1 (aka borreliella genomosp. 1)
E: borreliella burgdorferi b31 (borrelia burgdorferi str. b31) (aka borreliella burgdorferi b31)
F: None of the above. | [A] |
<Instruct>: Given the context 'Because Borrelia burgdorferi contains no intracellular iron, DNA is most likely not a major target for ROS via Fenton reaction.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [borrelia burgdorferi]
<Options>: A: borrelia africana (aka candidatus borrelia africana)
B: lyme disease spirochete (aka borreliella burgdorferi)
C: borreliales bacterium
D: borrelia
E: lyme disease borrelia (aka borreliella)
F: None of the above. | [B] |
<Instruct>: Given the context 'In support of this, growth of B. burgdorferi in the presence of 5 mM H2O2 had no effect on the DNA mutation rate (spontaneous coumermycin A1 resistance), and cells treated with 10 mM t-butyl hydroperoxide or 10 mM H2O2 show no increase in DNA damage.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelomyces (aka mycoplasma)
B: borrelia burgdorferi (aka borreliella burgdorferi)
C: borrelia fainii (aka candidatus borrelia fainii)
D: borrelia genomosp. 1 (aka borreliella genomosp. 1)
E: borrelia africana (aka candidatus borrelia africana)
F: None of the above. | [B] |
<Instruct>: Given the context 'Unlike most bacteria, B. burgdorferi incorporates ROS-susceptible polyunsaturated fatty acids from the environment into their membranes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia africana (aka candidatus borrelia africana)
B: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
C: borreliella americana (borrelia americana) (aka borreliella americana)
D: borrelia fainii (aka candidatus borrelia fainii)
E: borreliella burgdorferi b31 (borrelia burgdorferi str. b31) (aka borreliella burgdorferi b31)
F: None of the above. | [B] |
<Instruct>: Given the context 'Analysis of lipoxidase-treated B. burgdorferi cells by Electron Microscopy showed significant irregularities indicative of membrane damage.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: lyme disease spirochete (aka borreliella burgdorferi)
B: borrelia fainii (aka candidatus borrelia fainii)
C: borrelia
D: lyme disease borrelia (aka borreliella)
E: borrelia garinii (aka borreliella garinii)
F: None of the above. | [A] |
<Instruct>: Given the context 'These data suggest that B. burgdorferi membrane lipids are targets for attack by ROS encountered in the various stages of the infective cycle.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borreliales bacterium
B: borreliella (borrelia burgdorferi sensu lato) (aka borreliella)
C: borrelia fainii (aka candidatus borrelia fainii)
D: borrelia americana (aka borreliella americana)
E: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
F: None of the above. | [E] |
<Instruct>: Given the context 'Introduction
Borrelia burgdorferi, the causative agent of Lyme disease, survives and proliferates in distinctly different niches, including its arthropod vector and various mammalian hosts.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [borrelia burgdorferi]
<Options>: A: borrelia burgdorferi (aka borreliella burgdorferi)
B: borrelia fainii (aka candidatus borrelia fainii)
C: borrelia africana (aka candidatus borrelia africana)
D: borreliella burgdorferi b31 (borrelia burgdorferi str. b31) (aka borreliella burgdorferi b31)
E: borreliales bacterium
F: None of the above. | [A] |
<Instruct>: Given the context 'These ‘micro’ environments provide their own distinct sets of advantages and challenges to B. burgdorferi.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia africana (aka candidatus borrelia africana)
B: borreliella genomospecies 1 (aka borreliella genomosp. 1)
C: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
D: borreliella americana (borrelia americana) (aka borreliella americana)
E: borreliales bacterium
F: None of the above. | [C] |
<Instruct>: Given the context 'For example, during the initial stages of infection of the mammalian host, immune cells attempt to prevent B. burgdorferi from establishing an infection using several systems including those generating bacteriocidal reactive oxygen species (ROS)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borreliella (borrelia burgdorferi sensu lato) (aka borreliella)
B: borreliella americana (borrelia americana) (aka borreliella americana)
C: borrelia
D: borrelia burgdorferi (aka borreliella burgdorferi)
E: borrelia garinii (aka borreliella garinii)
F: None of the above. | [D] |
<Instruct>: Given the context 'For example, during the initial stages of infection of the mammalian host, immune cells attempt to prevent B. burgdorferi from establishing an infection using several systems including those generating bacteriocidal reactive oxygen species (ROS)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia
B: borreliella (borrelia burgdorferi sensu lato) (aka borreliella)
C: borrelia garinii (aka borreliella garinii)
D: borreliella americana (borrelia americana) (aka borreliella americana)
E: None of the above. | [E] |
<Instruct>: Given the context 'In order for B. burgdorferi to successfully colonize a new host and cause disease, they must overcome the challenges posed by the innate immune system including the deleterious effects of ROS/RNS compounds.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia burgdorferi b31 (aka borreliella burgdorferi b31)
B: lyme disease spirochete (aka borreliella burgdorferi)
C: borrelia
D: borrelia genomosp. 1 (aka borreliella genomosp. 1)
E: borrelia fainii (aka candidatus borrelia fainii)
F: None of the above. | [B] |
<Instruct>: Given the context 'Two notable exceptions are the photosynthetic bacteria which synthesize and incorporate significant levels of linoleic acid in their membrane (Tasaka et al., 1996) and Helicobacter pylori membranes which contain between 0.5% and 3% linoleic acid (Ursini and Bindoli, 1987).
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [helicobacter pylori]
<Options>: A: helicobacter cholecystus
B: helicobacter sp.
C: helicobacter nemestrinae (aka helicobacter pylori)
D: helicobacter bovis (aka candidatus helicobacter bovis)
E: helicobacter
F: None of the above. | [C] |
<Instruct>: Given the context 'The intracellular biochemistry of B. burgdorferi suggests that the primary cellular target of ROS may be distinct from that described in other bacteria such as Escherichia coli.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi; escherichia coli]
<Options>: A: escherichia faecalis ('escherichia faecalis') (aka escherichia faecalis)
B: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
C: escherichia sp.
D: borrelia
E: borreliella genomospecies 1 (aka borreliella genomosp. 1)
F: bacterium coli (aka escherichia coli)
G: borrelia burgdorferi group (aka borreliella)
H: enterobacteriaceae bacterium
I: enterobacteria (aka enterobacteriaceae)
J: borrelomyces (aka mycoplasma)
K: None of the above. | [B; F] |
<Instruct>: Given the context 'The intracellular biochemistry of B. burgdorferi suggests that the primary cellular target of ROS may be distinct from that described in other bacteria such as Escherichia coli.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi; escherichia coli]
<Options>: A: borreliales bacterium
B: enterobacteriaceae bacterium
C: borrelia burgdorferi (aka borreliella burgdorferi)
D: escherichia coli b (escherichia coli (strain b)) (aka escherichia coli b)
E: borrelia burgdorferi sensu lato (aka borreliella)
F: bacterium coli (aka escherichia coli)
G: enterobacteria (aka enterobacteriaceae)
H: escherichia phage
I: borrelia garinii (aka borreliella garinii)
J: borrelia africana (aka candidatus borrelia africana)
K: None of the above. | [C; F] |
<Instruct>: Given the context 'In E. coli, the extent of DNA damage due to H2O2 and Fenton chemistry is directly proportional to Fe metabolism and the free Fe concentration within the cell (10 µM) (Keyer and Imlay, 1996).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli]
<Options>: A: e. coli (aka escherichia coli)
B: enterobacterales (enterobacteriaceae and related endosymbionts) (aka enterobacterales)
C: unspecified coliform bacterium
D: enterobacteria (aka enterobacteriaceae)
E: escherichia coli k12 (aka escherichia coli k-12)
F: None of the above. | [A] |
<Instruct>: Given the context 'As the intracellular Fe concentrations of B. burgdorferi are estimated to be < 10 atoms per cell (Posey and Gherardini, 2000), it seems unlikely that DNA is a primary target for ROS.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borreliella burgdorferi b31 (borrelia burgdorferi str. b31) (aka borreliella burgdorferi b31)
B: borrelia africana (aka candidatus borrelia africana)
C: borreliales bacterium
D: borrelia
E: lyme disease spirochete (aka borreliella burgdorferi)
F: None of the above. | [E] |
<Instruct>: Given the context 'Therefore, the purpose of this study is to determine the biochemical effects of ROS on B. burgdorferi, including growth effects and biological/physical damage.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia
B: borreliella americana (borrelia americana) (aka borreliella americana)
C: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
D: borrelia burgdorferi b31 (aka borreliella burgdorferi b31)
E: borreliales bacterium
F: None of the above. | [C] |
<Instruct>: Given the context 'Results
Effect of ROS on B. burgdorferi cells
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borreliella americana (borrelia americana) (aka borreliella americana)
B: borrelia burgdorferi (aka borreliella burgdorferi)
C: borrelomyces (aka mycoplasma)
D: borrelia fainii (aka candidatus borrelia fainii)
E: borreliella genomospecies 1 (aka borreliella genomosp. 1)
F: None of the above. | [B] |
<Instruct>: Given the context 'Results
Effect of ROS on B. burgdorferi cells
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borreliella americana (borrelia americana) (aka borreliella americana)
B: borrelia fainii (aka candidatus borrelia fainii)
C: borreliella genomospecies 1 (aka borreliella genomosp. 1)
D: borrelomyces (aka mycoplasma)
E: None of the above. | [E] |
<Instruct>: Given the context 'In order to determine what the cellular targets of ROS in B. burgdorferi are, we first needed to determine the sensitivity of Borrelia cells to various oxidants.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia genomosp. 1 (aka borreliella genomosp. 1)
B: borrelia burgdorferi sensu lato (aka borreliella)
C: borrelia africana (aka candidatus borrelia africana)
D: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
E: borrelia fainii (aka candidatus borrelia fainii)
F: None of the above. | [D] |
<Instruct>: Given the context 'Microaerobic cultures of B. burgdorferi strain B31A3 were grown to a cell density of 5 × 107 cells ml−1, treated with varying concentrations of H2O2 (0–50 mM) or t-butyl hydroperoxide (0–50 mM) and the number of surviving cells determined by plating.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borreliella genomospecies 1 (aka borreliella genomosp. 1)
B: candidatus borrelia africana (borrelia africana) (aka candidatus borrelia africana)
C: borrelia burgdorferi group (aka borreliella)
D: borrelia burgdorferi (aka borreliella burgdorferi)
E: borrelia americana (aka borreliella americana)
F: None of the above. | [D] |
<Instruct>: Given the context 'In contrast, when E. coli cells were exposed to 1 mM t-butyl hydroperoxide, approximately 1% of the cells survive.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli]
<Options>: A: prokaryotes (aka bacteria)
B: escherichia
C: enterococcus coli (aka escherichia coli)
D: enterobacteria (aka enterobacteriaceae)
E: enterobacteriales (aka enterobacterales)
F: None of the above. | [C] |
<Instruct>: Given the context 'B. burgdorferi cells were much more resistant to t-butyl hydroperoxide than E. coli cells, with a survival rate of approximately 100% at 1 mM t-butyl hydroperoxide.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi; e. coli]
<Options>: A: enterobacteria (aka enterobacteriaceae)
B: borrelia garinii (aka borreliella garinii)
C: escherichia phage
D: 'escherichia faecalis' (aka escherichia faecalis)
E: borrelia
F: borrelia africana (aka candidatus borrelia africana)
G: borrelomyces (aka mycoplasma)
H: bacillus coli (aka escherichia coli)
I: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
J: escherichia
K: None of the above. | [I; H] |
<Instruct>: Given the context 'B. burgdorferi cells were much more resistant to t-butyl hydroperoxide than E. coli cells, with a survival rate of approximately 100% at 1 mM t-butyl hydroperoxide.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi; e. coli]
<Options>: A: escherichia coli b (escherichia coli (strain b)) (aka escherichia coli b)
B: borrelia africana (aka candidatus borrelia africana)
C: escherichia
D: bacillus coli (aka escherichia coli)
E: borrelia americana (aka borreliella americana)
F: borrelia garinii (aka borreliella garinii)
G: escherichia phage
H: unspecified coliform bacterium
I: borrelomyces (aka mycoplasma)
J: lyme disease spirochete (aka borreliella burgdorferi)
K: None of the above. | [J; D] |
<Instruct>: Given the context 'E. coli cells exposed to 1 mM H2O2 have approximately 10% survivability, while 100% of the B. burgdorferi cells survive at this concentration, and approximately 80% survive when exposed to 10 mM H2O2 (Fig. 1B).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli; b. burgdorferi]
<Options>: A: candidatus borrelia africana (borrelia africana) (aka candidatus borrelia africana)
B: enterobacteria (aka enterobacteriaceae)
C: enterobacteriaceae bacterium
D: lyme disease spirochete (aka borreliella burgdorferi)
E: prokaryotes (aka bacteria)
F: 'escherichia faecalis' (aka escherichia faecalis)
G: borrelia garinii (aka borreliella garinii)
H: borrelia americana (aka borreliella americana)
I: borreliales bacterium
J: enterococcus coli (aka escherichia coli)
K: None of the above. | [J; D] |
<Instruct>: Given the context 'E. coli cells exposed to 1 mM H2O2 have approximately 10% survivability, while 100% of the B. burgdorferi cells survive at this concentration, and approximately 80% survive when exposed to 10 mM H2O2 (Fig. 1B).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli; b. burgdorferi]
<Options>: A: borreliella (borrelia burgdorferi sensu lato) (aka borreliella)
B: enterobacteriaceae bacterium
C: lyme disease spirochete (aka borreliella burgdorferi)
D: enterobacteriales (aka enterobacterales)
E: unspecified coliform bacterium
F: escherichia phage
G: borrelia africana (aka candidatus borrelia africana)
H: borrelia fainii (aka candidatus borrelia fainii)
I: escherichia coli (escherichia/shigella coli) (aka escherichia coli)
J: borrelia garinii (aka borreliella garinii)
K: None of the above. | [I; C] |
<Instruct>: Given the context 'Taken together, these data indicated that B. burgdorferi strain B31A3 was highly resistant to exposure to both t-butyl peroxide and H2O2.
Borrelia burgdorferi DNA is not the primary target of ROS
For most bacteria, DNA is the major target of ROS causing a wide variety of DNA lesions.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi; borrelia burgdorferi]
<Options>: A: borreliella genomospecies 1 (aka borreliella genomosp. 1)
B: borrelia garinii (aka borreliella garinii)
C: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
D: borreliella (borrelia burgdorferi sensu lato) (aka borreliella)
E: borreliales bacterium
F: borrelomyces (aka mycoplasma)
G: borrelia africana (aka candidatus borrelia africana)
H: borrelia fainii (aka candidatus borrelia fainii)
I: borrelia americana (aka borreliella americana)
J: None of the above. | [C; C] |
<Instruct>: Given the context 'Taken together, these data indicated that B. burgdorferi strain B31A3 was highly resistant to exposure to both t-butyl peroxide and H2O2.
Borrelia burgdorferi DNA is not the primary target of ROS
For most bacteria, DNA is the major target of ROS causing a wide variety of DNA lesions.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi; borrelia burgdorferi]
<Options>: A: borrelia genomosp. 1 (aka borreliella genomosp. 1)
B: borrelia
C: borreliales bacterium
D: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
E: borrelia americana (aka borreliella americana)
F: candidatus borrelia africana (borrelia africana) (aka candidatus borrelia africana)
G: borrelia fainii (aka candidatus borrelia fainii)
H: None of the above. | [D; D] |
<Instruct>: Given the context 'However, B. burgdorferi has been shown to harbour few genes encoding orthologues of known iron-containing proteins, does not require Fe for growth and has intracellular Fe concentrations estimated to be < 10 atoms per cell (Posey and Gherardini, 2000).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia fainii (aka candidatus borrelia fainii)
B: borrelia americana (aka borreliella americana)
C: borrelia garinii (aka borreliella garinii)
D: borrelia burgdorferi sensu lato (aka borreliella)
E: borrelia burgdorferi (aka borreliella burgdorferi)
F: None of the above. | [E] |
<Instruct>: Given the context 'Taken together, these observations strongly suggest that B. burgdorferi DNA is not a major target for ROS.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia garinii (aka borreliella garinii)
B: borreliella burgdorferi b31 (borrelia burgdorferi str. b31) (aka borreliella burgdorferi b31)
C: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
D: borrelia africana (aka candidatus borrelia africana)
E: borrelomyces (aka mycoplasma)
F: None of the above. | [C] |
<Instruct>: Given the context 'To test this hypothesis, different techniques were used to measure DNA damage in B. burgdorferi cells after exposure to ROS.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia africana (aka candidatus borrelia africana)
B: borrelomyces (aka mycoplasma)
C: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
D: borreliella genomospecies 1 (aka borreliella genomosp. 1)
E: borrelia garinii (aka borreliella garinii)
F: None of the above. | [C] |
<Instruct>: Given the context 'In B. burgdorferi, mutations that confer resistance to coumermycin A1, which targets the β subunit of DNA gyrase, have been mapped to gyrB, the gene encoding DNA gyrase B (Samuels et al., 1994).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia burgdorferi (aka borreliella burgdorferi)
B: borrelia genomosp. 1 (aka borreliella genomosp. 1)
C: borreliales bacterium
D: borreliella (borrelia burgdorferi sensu lato) (aka borreliella)
E: borrelia garinii (aka borreliella garinii)
F: None of the above. | [A] |
<Instruct>: Given the context 'To determine if exposure to oxidants increases DNA damage by increasing point mutations, B. burgdorferi B31A3 cells grown under microaerobic conditions were treated with 5 mM H2O2 and plated in the presence and absence of 250 ng ml−1 coumermycin A1.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelomyces (aka mycoplasma)
B: lyme disease borrelia (aka borreliella)
C: borrelia burgdorferi (aka borreliella burgdorferi)
D: borreliella burgdorferi b31 (borrelia burgdorferi str. b31) (aka borreliella burgdorferi b31)
E: borreliella americana (borrelia americana) (aka borreliella americana)
F: None of the above. | [C] |
<Instruct>: Given the context 'To determine if exposure to oxidants increases DNA damage by increasing point mutations, B. burgdorferi B31A3 cells grown under microaerobic conditions were treated with 5 mM H2O2 and plated in the presence and absence of 250 ng ml−1 coumermycin A1.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: lyme disease borrelia (aka borreliella)
B: borreliella americana (borrelia americana) (aka borreliella americana)
C: borrelomyces (aka mycoplasma)
D: borreliella burgdorferi b31 (borrelia burgdorferi str. b31) (aka borreliella burgdorferi b31)
E: None of the above. | [E] |
<Instruct>: Given the context 'To determine whether ROS can damage B. burgdorferi DNA, strain B31A3 cells grown under microaerobic conditions were treated with H2O2 (1 or 10 mM), t-butyl hydroperoxide (1 or 10 mM) or lipoxidase (an enzyme which specifically catalyses the hydroperoxidation of lipids containing a cis, cis-pentadiene structure, such as linoleic acid).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: lyme disease spirochete (aka borreliella burgdorferi)
B: borrelia africana (aka candidatus borrelia africana)
C: borrelia genomosp. 1 (aka borreliella genomosp. 1)
D: borrelia garinii (aka borreliella garinii)
E: borrelia
F: None of the above. | [A] |
<Instruct>: Given the context 'In contrast, when E. coli strain TA4315 cells (ahpCF) (Storz et al., 1989) were treated with 100 µM H2O2, the number of AP sites increased ∼10-fold over untreated cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli]
<Options>: A: prokaryotes (aka bacteria)
B: enterobacterales (enterobacteriaceae and related endosymbionts) (aka enterobacterales)
C: unspecified coliform bacterium
D: escherichia coli b (escherichia coli (strain b)) (aka escherichia coli b)
E: enterococcus coli (aka escherichia coli)
F: None of the above. | [E] |
<Instruct>: Given the context 'These data suggest that B. burgdorferi DNA was not a major target for oxidative damage under these conditions.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia americana (aka borreliella americana)
B: borrelia
C: lyme disease spirochete (aka borreliella burgdorferi)
D: borrelia garinii (aka borreliella garinii)
E: lyme disease borrelia (aka borreliella)
F: None of the above. | [C] |
<Instruct>: Given the context 'It is of note to mention that the total number of AP sites per 105 bp DNA is approximately 10-fold higher in untreated Borrelia B31A3 DNA than in untreated E. coli DNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli]
<Options>: A: 'escherichia faecalis' (aka escherichia faecalis)
B: bacterium coli (aka escherichia coli)
C: escherichia
D: escherichia sp.
E: enterobacteria (aka enterobacteriaceae)
F: None of the above. | [B] |
<Instruct>: Given the context 'The B. burgdorferi strain B31A3 harbours 11 linear plasmids and a linear chromosome with ∼100 unpaired bases in the telomere loops per genome or 10 bases per 105 bp DNA (Hinnebusch and Barbour, 1991; Chaconas, 2005).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia
B: borrelomyces (aka mycoplasma)
C: borreliella americana (borrelia americana) (aka borreliella americana)
D: candidatus borrelia africana (borrelia africana) (aka candidatus borrelia africana)
E: lyme disease spirochete (aka borreliella burgdorferi)
F: None of the above. | [E] |
<Instruct>: Given the context 'To test this hypothesis, the AP sites were measured in DNA isolated from untreated B. burgdorferi strain B314 which harbours no linear plasmids (Sadziene et al., 1993).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia fainii (aka candidatus borrelia fainii)
B: borreliella genomospecies 1 (aka borreliella genomosp. 1)
C: borreliella burgdorferi b31 (borrelia burgdorferi str. b31) (aka borreliella burgdorferi b31)
D: borrelia garinii (aka borreliella garinii)
E: lyme disease spirochete (aka borreliella burgdorferi)
F: None of the above. | [E] |
<Instruct>: Given the context 'The analyses of the AP sites strongly suggested that B. burgdorferi DNA was not the major target for oxidative damage.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
B: borrelomyces (aka mycoplasma)
C: borrelia africana (aka candidatus borrelia africana)
D: borreliales bacterium
E: borrelia americana (aka borreliella americana)
F: None of the above. | [A] |
<Instruct>: Given the context 'To determine whether ROS can damage B. burgdorferi DNA and cause 8-oxoguanine lesions, strain B31A3 cells grown under microaerobic conditions were treated with H2O2 (5 or 10 mM), t-butyl hydroperoxide (5 or 10 mM) or lipoxidase.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia
B: borreliella burgdorferi b31 (borrelia burgdorferi str. b31) (aka borreliella burgdorferi b31)
C: borrelia fainii (aka candidatus borrelia fainii)
D: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
E: borreliella americana (borrelia americana) (aka borreliella americana)
F: None of the above. | [D] |
<Instruct>: Given the context 'In contrast, when a MutM (the specific glycosylase that removes the 8-oxoguanine)-deficient E. coli strain was treated with 100 µM H2O2, the amount of 8-oxoguanine sites increased ∼fivefold over untreated cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli]
<Options>: A: enterobacteriaceae bacterium
B: enterobacterales (enterobacteriaceae and related endosymbionts) (aka enterobacterales)
C: escherichia phage
D: unspecified coliform bacterium
E: e. coli (aka escherichia coli)
F: None of the above. | [E] |
<Instruct>: Given the context 'It is important to point out that no MutM homologue has been identified in the genome of B. burgdorferi.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia burgdorferi (aka borreliella burgdorferi)
B: borrelia
C: borreliella burgdorferi b31 (borrelia burgdorferi str. b31) (aka borreliella burgdorferi b31)
D: borrelomyces (aka mycoplasma)
E: borrelia americana (aka borreliella americana)
F: None of the above. | [A] |
<Instruct>: Given the context 'It is important to point out that no MutM homologue has been identified in the genome of B. burgdorferi.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia
B: borrelomyces (aka mycoplasma)
C: borreliella burgdorferi b31 (borrelia burgdorferi str. b31) (aka borreliella burgdorferi b31)
D: borrelia americana (aka borreliella americana)
E: None of the above. | [E] |
<Instruct>: Given the context 'Taken together, these data suggested that B. burgdorferi DNA was not a major target for oxidative damage under these conditions.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borreliales bacterium
B: borreliella americana (borrelia americana) (aka borreliella americana)
C: borrelia africana (aka candidatus borrelia africana)
D: borrelomyces (aka mycoplasma)
E: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
F: None of the above. | [E] |
<Instruct>: Given the context 'The membranes of B. burgdorferi are targeted during oxidative stress
In eukaryotes, membrane lipids are a major target of ROS.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borreliella burgdorferi b31 (borrelia burgdorferi str. b31) (aka borreliella burgdorferi b31)
B: borrelia africana (aka candidatus borrelia africana)
C: borrelia garinii (aka borreliella garinii)
D: borrelia americana (aka borreliella americana)
E: lyme disease spirochete (aka borreliella burgdorferi)
F: None of the above. | [E] |
<Instruct>: Given the context 'As B. burgdorferi cannot synthesize their own lipids, they must instead scavenge them.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borreliella americana (borrelia americana) (aka borreliella americana)
B: borrelia fainii (aka candidatus borrelia fainii)
C: borreliella (borrelia burgdorferi sensu lato) (aka borreliella)
D: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
E: candidatus borrelia africana (borrelia africana) (aka candidatus borrelia africana)
F: None of the above. | [D] |
<Instruct>: Given the context 'To determine if B. burgdorferi contains polyunsaturated lipids, B. burgdorferi strain B31A3 was grown under anaerobic conditions and analysed for fatty acid composition by Lipid Technologies (Austin, MN).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelia garinii (aka borreliella garinii)
B: borreliella genomospecies 1 (aka borreliella genomosp. 1)
C: borreliella burgdorferi b31 (borrelia burgdorferi str. b31) (aka borreliella burgdorferi b31)
D: borrelomyces (aka mycoplasma)
E: borrelia burgdorferi (aka borreliella burgdorferi)
F: None of the above. | [E] |
<Instruct>: Given the context 'To determine if Borrelia polyunsaturated lipids can undergo lipid peroxidation, B. burgdorferi B31A3 cells grown microaerobically were treated with 1 mM t-butyl hydroperoxide or 250 mg of lipoxidase, and the cell pellets were analysed for fatty acid composition (Industrial Laboratory).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borreliella burgdorferi b31 (borrelia burgdorferi str. b31) (aka borreliella burgdorferi b31)
B: borrelia burgdorferi (aka borreliella burgdorferi)
C: borreliella genomospecies 1 (aka borreliella genomosp. 1)
D: candidatus borrelia africana (borrelia africana) (aka candidatus borrelia africana)
E: borrelia
F: None of the above. | [B] |
<Instruct>: Given the context 'These data indicated that the linoleic acid present in B. burgdorferi membranes can be oxidized by ROS.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: candidatus borrelia africana (borrelia africana) (aka candidatus borrelia africana)
B: borrelia burgdorferi (aka borreliella burgdorferi)
C: borrelia fainii (aka candidatus borrelia fainii)
D: borreliella americana (borrelia americana) (aka borreliella americana)
E: borrelomyces (aka mycoplasma)
F: None of the above. | [B] |
<Instruct>: Given the context 'As a control, eukaryotic cells (mouse myeloma cells SP2) were treated with AAPH and MDA measured (Fig.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: mus (aka mus <genus>) (aka mus <genus>)
C: mus musculus (house mouse) (aka mus musculus)
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: peromyscus
F: None of the above. | [C] |
<Instruct>: Given the context 'Mouse myeloma cells have been used as a model system for the determination of phospholipid hydroperoxides (Chotimarkorn et al., 2005).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse]
<Options>: A: mus sp. (mice (aka mus sp.))
B: mus <subgenus> (mus (aka mus <subgenus>))
C: mus molossinus (aka mus musculus molossinus)
D: mus musculus (house mouse) (aka mus musculus)
E: mouse (aka mus <genus>)
F: None of the above. | [D] |
<Instruct>: Given the context 'To determine if the Borrelia lipids are damaged from growth in an oxygen environment, B. burgdorferi B31A3 cells were grown under anaerobic, microaerobic and aerobic conditions and MDA measured.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelomyces (aka mycoplasma)
B: borrelia burgdorferi (aka borreliella burgdorferi)
C: borreliella (borrelia burgdorferi sensu lato) (aka borreliella)
D: borrelia americana (aka borreliella americana)
E: borreliales bacterium
F: None of the above. | [B] |
<Instruct>: Given the context 'Our High Performance Liquid Chromatography analyses of the MDA present in anaerobically grown B. burgdorferi cells showed a small peak with a retention time similar to that of the MDA standard.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borreliella genomospecies 1 (aka borreliella genomosp. 1)
B: borrelia garinii (aka borreliella garinii)
C: borreliella burgdorferi (lyme disease spirochete) (aka borreliella burgdorferi)
D: borreliella (borrelia burgdorferi sensu lato) (aka borreliella)
E: borrelomyces (aka mycoplasma)
F: None of the above. | [C] |
<Instruct>: Given the context 'Our High Performance Liquid Chromatography analyses of the MDA present in anaerobically grown B. burgdorferi cells showed a small peak with a retention time similar to that of the MDA standard.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: borrelomyces (aka mycoplasma)
B: borreliella genomospecies 1 (aka borreliella genomosp. 1)
C: borrelia garinii (aka borreliella garinii)
D: borreliella (borrelia burgdorferi sensu lato) (aka borreliella)
E: None of the above. | [E] |
<Instruct>: Given the context 'To visualize the lipid hydroperoxides, B. burgdorferi B31A3 cells were labelled with DPPP and observed by fluorescence microscopy (Fig. 5B).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b. burgdorferi]
<Options>: A: lyme disease spirochete (aka borreliella burgdorferi)
B: borrelia garinii (aka borreliella garinii)
C: borrelia fainii (aka candidatus borrelia fainii)
D: borreliales bacterium
E: candidatus borrelia africana (borrelia africana) (aka candidatus borrelia africana)
F: None of the above. | [A] |
<Instruct>: Given the context 'E. coli Top10 cells and mouse myeloma SP2 cells were also labelled and visualized to serve as negative and positive controls respectively (Fig.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli; mouse]
<Options>: A: unspecified coliform bacterium
B: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
C: mouse (aka mus musculus)
D: escherichia/shigella coli (aka escherichia coli)
E: peromyscus
F: escherichia phage
G: 'escherichia faecalis' (aka escherichia faecalis)
H: mus molossinus (aka mus musculus molossinus)
I: prokaryotes (aka bacteria)
J: mus sp. (mice (aka mus sp.))
K: None of the above. | [D; C] |
<Instruct>: Given the context 'E. coli Top10 cells and mouse myeloma SP2 cells were also labelled and visualized to serve as negative and positive controls respectively (Fig.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli; mouse]
<Options>: A: enterobacteria (aka enterobacteriaceae)
B: mus <genus> (mice (aka mus <genus>))
C: peromyscus
D: escherichia coli (escherichia/shigella coli) (aka escherichia coli)
E: escherichia coli (strain b) (aka escherichia coli b)
F: unspecified coliform bacterium
G: mouse (aka mus musculus)
H: mus cricetus (aka cricetus cricetus)
I: escherichia coli k12 (aka escherichia coli k-12)
J: mus molossinus (aka mus musculus molossinus)
K: None of the above. | [D; G] |
<Instruct>: Given the context '5B) and for the mouse myeloma cells (Fig. 5C), but not for the E. coli cells (Fig. 5A).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse; e. coli]
<Options>: A: mus <subgenus> (mus (aka mus <subgenus>))
B: enterobacteriaceae bacterium
C: enterobacteria (aka enterobacteriaceae)
D: peromyscus
E: mus cricetus (aka cricetus cricetus)
F: escherichia coli k12 (aka escherichia coli k-12)
G: mus musculus (house mouse) (aka mus musculus)
H: unspecified coliform bacterium
I: mus <genus> (mice (aka mus <genus>))
J: bacterium coli (aka escherichia coli)
K: None of the above. | [G; J] |
<Instruct>: Given the context '5B) and for the mouse myeloma cells (Fig. 5C), but not for the E. coli cells (Fig. 5A).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse; e. coli]
<Options>: A: house mouse (aka mus musculus)
B: mus <subgenus> (mus (aka mus <subgenus>))
C: escherichia
D: mus molossinus (aka mus musculus molossinus)
E: mus (aka mus <genus>) (aka mus <genus>)
F: enterobacteria (aka enterobacteriaceae)
G: escherichia phage
H: mus sp. (mice (aka mus sp.))
I: bacillus coli (aka escherichia coli)
J: enterobacteriales (aka enterobacterales)
K: None of the above. | [A; I] |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.