instruction stringlengths 225 2.35k | input stringlengths 89 1.5k | response stringclasses 698 values |
|---|---|---|
<Instruct>: Given the context 'INTRODUCTION
In mammals DNA polymerase a is thought to be the replicative
enzyme, but due to low levels of activity, even in tissues actively making DNA, and to enzyme heterogeneity it has been found difficult to purify
However, small samples of DNA polymerase a have been highly purified
2, 3, 4, 5 from several sources and partially characterised
Heterogeneity has been observed in DNA polymerase a from a var
6 7
iety of sources, including rat liver and spleen , Hela cells, baby hamster
8 9, 10 11
kidney cells , mouse myeloma , Drosophila embryos and calf thymus
1,6, 12, 13 .', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rat; mouse; drosophila; calf]
<Options>: A: rattus rattoides (aka rattus rattus)
B: mus cricetus (aka cricetus cricetus)
C: melanogaster (aka melanogaster <flies>)
D: rattus norvegicus albus
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: mice (aka mus sp.) (aka mus sp.)
G: house mouse (aka mus musculus)
H: sueus
I: horse (aka equus caballus)
J: fruit flies (aka drosophila <flies,genus>)
K: domestic cow (aka bos taurus)
L: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
M: bovidae
N: rat (aka rattus) (aka rattus)
O: melanogaster <basidiomycete fungi> (melanogaster) (aka melanogaster <basidiomycete fungi>)
P: mus norvegicus (aka rattus norvegicus)
Q: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
R: equetus
S: flies (aka diptera)
T: fruit fly (aka drosophila melanogaster)
U: None of the above. | [P; G; J; K] |
<Instruct>: Given the context 'INTRODUCTION
In mammals DNA polymerase a is thought to be the replicative
enzyme, but due to low levels of activity, even in tissues actively making DNA, and to enzyme heterogeneity it has been found difficult to purify
However, small samples of DNA polymerase a have been highly purified
2, 3, 4, 5 from several sources and partially characterised
Heterogeneity has been observed in DNA polymerase a from a var
6 7
iety of sources, including rat liver and spleen , Hela cells, baby hamster
8 9, 10 11
kidney cells , mouse myeloma , Drosophila embryos and calf thymus
1,6, 12, 13 .', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rat; mouse; drosophila; calf]
<Options>: A: fruit fly (aka drosophila <flies,genus>)
B: drosophila <flies,subgenus> (drosophila) (aka drosophila <flies,subgenus>)
C: mus <subgenus> (mus (aka mus <subgenus>))
D: bactrocera melanogaster (bactrocera (bactrocera) melanogaster) (aka bactrocera melanogaster)
E: rattus (rats (aka rattus))
F: melanogaster group
G: rattus sp. (rats (aka rattus sp.))
H: boveria
I: bovine (aka bos taurus)
J: bovidae
K: rattus norvegicus (rats (aka rattus norvegicus))
L: equus subg. equus (aka equus)
M: peromyscus
N: mus cricetus (aka cricetus cricetus)
O: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
P: mouse (aka mus musculus)
Q: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
R: black rat (aka rattus rattus)
S: drosophila <basidiomycete fungi> (drosophila) (aka drosophila <basidiomycete fungi>)
T: equetus
U: None of the above. | [K; P; A; I] |
<Instruct>: Given the context 'We have previously observed several species of calf thymus
DNA polymerase a differing in size and charge .', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [calf]
<Options>: A: bovidae
B: bos bovis (aka bos taurus)
C: equetus
D: mus spretus (mus musculus spretus) (aka mus spretus)
E: horses (aka equidae)
F: None of the above. | [B] |
<Instruct>: Given the context '5S enzymes, analagous to B, have been observed to
C Information Retrieval Limited 1 Falconberg Court London Wl V 5FG England
3341
Nucleic Acids Research
arise as the result of proteolytic action ' , similarly the B enzyme above 14
,but the relationship of the other observed species is not clear, nor is
the problem of which, if any, of these species is the replicative enzyme,
although circumstantial evidence has implicated a DNA polymerase a to be
15 the replicative enzyme in adenovirus infected KB cells
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [adenovirus]
<Options>: A: unidentified adenovirus (adenovirus) (aka unidentified adenovirus)
B: avian adeno-associated virus
C: adeno-associated virus clade d
D: human adenovirus sp. (human adenovirus) (aka human adenovirus sp.)
E: adintoviridae
F: None of the above. | [A] |
<Instruct>: Given the context 'MATERIALS AND METHODS
Calf thymus was obtained from 10-16 week old calves and frozen at
-20?C until required.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [calf; calves]
<Options>: A: horse (aka equus caballus)
B: gallus
C: horses (aka equidae)
D: equus subg. equus (aka equus)
E: equetus
F: equidae (horses) (aka equidae)
G: bos bovis (aka bos taurus)
H: bos (cattle) (aka bos)
I: None of the above. | [G; G] |
<Instruct>: Given the context 'MATERIALS AND METHODS
Calf thymus was obtained from 10-16 week old calves and frozen at
-20?C until required.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [calf; calves]
<Options>: A: gallus
B: equidae (horses) (aka equidae)
C: horse (aka equus caballus)
D: equetus
E: equus subg. equus (aka equus)
F: horses (aka equidae)
G: bos (cattle) (aka bos)
H: None of the above. | [H; H] |
<Instruct>: Given the context 'MATERIALS AND METHODS
Calf thymus was obtained from 10-16 week old calves and frozen at
-20?C until required.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [calf; calves]
<Options>: A: equine (aka equus caballus)
B: equidae (horses) (aka equidae)
C: gallus
D: bovine (aka bos taurus)
E: equetus
F: bovidae
G: mus spretus (mus musculus spretus) (aka mus spretus)
H: boveria
I: bos taurus indicus (aka bos indicus)
J: None of the above. | [D; D] |
<Instruct>: Given the context '5 p.g bovine serum albumin, 1 ,ug template-initiator complex, enzyme protein and the relevant [ H] deoxynucleoside triphosphate at 0.1 mM and 12-15 cpm/pmol.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bovine]
<Options>: A: bos taurus x bos indicus (aka bos indicus x bos taurus)
B: bos taurus (bos primigenius taurus) (aka bos taurus)
C: bos sp.
D: bovidae
E: bos indicus (bos primigenius indicus) (aka bos indicus)
F: None of the above. | [B] |
<Instruct>: Given the context 'When the calf
20FI: Now ~ ~ ~ 20 20Fr Na 06
Figure 2 DEAE cellulose elution profile of calf thymus DNA polymerase a. 47, 000 units, 97 mg of Fraction IV enzyme prepared from 415 g of calf
thymus were loaded on to a 10 x 1.8 cm DEAE cellulose column, after washing with 0.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [calf]
<Options>: A: sueus
B: equus subg. asinus (aka equus)
C: cattle (aka bos)
D: equine (aka equus caballus)
E: cow (aka bos taurus) (aka bos taurus)
F: None of the above. | [E] |
<Instruct>: Given the context 'It has also been concluded that the heterogeneity in the
1 ~~~~~~~~~~~~~~~~~3 mouse myeloma DNA polymerase a fraction is not due to proteolysis .', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: mus <subgenus> (mus (aka mus <subgenus>))
C: mouse (aka mus musculus)
D: mus molossinus (aka mus musculus molossinus)
E: peromyscus
F: None of the above. | [C] |
<Instruct>: Given the context 'The molecular weight standards were: (1) bovine serum albumin dimer (134, 000), (2) ,3 galactosidase (130, 000), (3) phosphorylase a (94, 000), (4) bovine serum
albumin (68, 000), (5) pyruvate kinase (57, 000) and (6) lactate dehydrogenase (35, 000).
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bovine]
<Options>: A: bos taurus x bos indicus (aka bos indicus x bos taurus)
B: domestic cattle (aka bos taurus)
C: bos sp.
D: bos bubalis (aka bubalus bubalis)
E: bovinae
F: None of the above. | [B] |
<Instruct>: Given the context 'The human KB cell
DNA polymerase a, equivalent to the C enzyme, has been reported to consist
4
of subunits of 76, 000 and 66, 000 molecular weight , but at no time have we
observed polypeptide bands at 76, 000 and 66, 000 rising and falling with
enzyme activity in any gels of calf thyrrmus enzymes A1, A and C (and
2 unpublished observations).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human; calf]
<Options>: A: equetus
B: macrobiotus sapiens
C: bovine (aka bos taurus)
D: human (aka homo sapiens)
E: species
F: sueus
G: boveria
H: humans (aka homo)
I: equine (aka equus caballus)
J: this
K: None of the above. | [D; C] |
<Instruct>: Given the context 'The human KB cell
DNA polymerase a, equivalent to the C enzyme, has been reported to consist
4
of subunits of 76, 000 and 66, 000 molecular weight , but at no time have we
observed polypeptide bands at 76, 000 and 66, 000 rising and falling with
enzyme activity in any gels of calf thyrrmus enzymes A1, A and C (and
2 unpublished observations).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human; calf]
<Options>: A: probles
B: species
C: equus subg. asinus (aka equus)
D: human (aka homo sapiens)
E: mus spretus (mus musculus spretus) (aka mus spretus)
F: bos bovis (aka bos taurus)
G: gallus
H: macrobiotus sapiens
I: animals (aka metazoa)
J: sueus
K: None of the above. | [D; F] |
<Instruct>: Given the context 'The human KB cell
DNA polymerase a, equivalent to the C enzyme, has been reported to consist
4
of subunits of 76, 000 and 66, 000 molecular weight , but at no time have we
observed polypeptide bands at 76, 000 and 66, 000 rising and falling with
enzyme activity in any gels of calf thyrrmus enzymes A1, A and C (and
2 unpublished observations).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human; calf]
<Options>: A: mus spretus (mus musculus spretus) (aka mus spretus)
B: sueus
C: species
D: equus subg. asinus (aka equus)
E: animals (aka metazoa)
F: human (aka homo sapiens)
G: gallus
H: macrobiotus sapiens
I: probles
J: None of the above. | [F; J] |
<Instruct>: Given the context 'M sodium
pyrophosphate containing 100 ,ug/ml native calf thymus DNA and processed for counting in the usual manner6.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [calf]
<Options>: A: mus spretus (mus musculus spretus) (aka mus spretus)
B: boveria
C: sueus
D: bovidae
E: cow (aka bos taurus) (aka bos taurus)
F: None of the above. | [E] |
<Instruct>: Given the context '[3H] dTTP (15 cpm/pmol), 312.5 ,ug bovine serum albumin, 5 Fg poly (dA).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bovine]
<Options>: A: bos taurus x bos indicus (aka bos indicus x bos taurus)
B: bos taurus (bos primigenius taurus) (aka bos taurus)
C: bos bubalis bubalis (aka bubalus bubalis bubalis)
D: bovidae
E: boveria
F: None of the above. | [B] |
<Instruct>: Given the context 'Integration in primary community care networks (PCCNs): examination of governance, clinical, marketing, financial, and information infrastructures in a national demonstration project in Taiwan
Abstract
Background
Taiwan's primary community care network (PCCN) demonstration project, funded by the Bureau of National Health Insurance on March 2003, was established to discourage hospital shopping behavior of people and drive the traditional fragmented health care providers into cooperate care models.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [people]
<Options>: A: this
B: homo (humans) (aka homo)
C: homo sapiens (human) (aka homo sapiens)
D: avian (aka aves)
E: psyche
F: None of the above. | [C] |
<Instruct>: Given the context 'By June 2003 the number of people insured had reached 21,956,729 (99%).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [people]
<Options>: A: human (aka homo sapiens)
B: suborder
C: genus
D: species
E: species group
F: None of the above. | [A] |
<Instruct>: Given the context 'The unique phenomenon characterized in Taiwan health care industry different from those in the western countries is the freedom of patients to choose the health care providers they want, no matter what their disease severity is.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patients]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: humans (aka homo)
C: other (aka unidentified)
D: genus
E: suborder
F: None of the above. | [A] |
<Instruct>: Given the context 'Furthermore, Taiwan people favor the larger scales of facilities and this fallacy leads to the phenomenon of big-hospital shopping.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [people]
<Options>: A: musculus
B: probles
C: psyche
D: homo sapiens (human) (aka homo sapiens)
E: genus
F: None of the above. | [D] |
<Instruct>: Given the context 'For example, people choose the medical centers which are accredited as the highest level of medical science in Taiwan when they only suffer from a common cold.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [people]
<Options>: A: humans (aka homo)
B: animals (aka metazoa)
C: probles
D: musculus
E: human (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'In the spring of 2003, the SARS epidemic viciously attacked the health of Taiwan's people.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [people]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: family
C: this
D: species group
E: probles
F: None of the above. | [A] |
<Instruct>: Given the context 'The people's freedom to choose medical providers caused the national health authority to barely control and traced the flow of epidemic.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [people]
<Options>: A: homo (humans) (aka homo)
B: kingdom
C: homo sapiens (human) (aka homo sapiens)
D: probles
E: other (aka unidentified)
F: None of the above. | [C] |
<Instruct>: Given the context 'The idea of member component design in PCCNs was aimed to lead the Taiwan citizens to choose one clinic physician as their personal family physician for health maintenance and this family physician also would have the responsibility of referring the patients to specialty care if necessary.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patients]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: species
C: subsection
D: other (aka unidentified)
E: genus
F: None of the above. | [A] |
<Instruct>: Given the context 'The idea of member component design in PCCNs was aimed to lead the Taiwan citizens to choose one clinic physician as their personal family physician for health maintenance and this family physician also would have the responsibility of referring the patients to specialty care if necessary.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patients]
<Options>: A: genus
B: species
C: subsection
D: other (aka unidentified)
E: None of the above. | [E] |
<Instruct>: Given the context 'From a national health authority perspective, they expected the Taiwan people to put an end to their fallacy that "bigger is better" for health care organizations and establish the idea of "human health", starting with prevention and primary care, followed by secondary or tertiary care, emphasizing health promotion and maintenance instead of disease curing.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [people; human]
<Options>: A: placental mammals (aka eutheria)
B: birds (aka aves)
C: humans (aka homo)
D: musculus
E: species group
F: species
G: probles
H: homo sapiens (human) (aka homo sapiens)
I: None of the above. | [H; H] |
<Instruct>: Given the context 'From a national health authority perspective, they expected the Taiwan people to put an end to their fallacy that "bigger is better" for health care organizations and establish the idea of "human health", starting with prevention and primary care, followed by secondary or tertiary care, emphasizing health promotion and maintenance instead of disease curing.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [people; human]
<Options>: A: human (aka homo sapiens)
B: primate (aka primates)
C: animals (aka metazoa)
D: eutherian mammals (aka eutheria)
E: species
F: probles
G: psyche
H: cellular organisms (biota) (aka cellular organisms)
I: None of the above. | [A; A] |
<Instruct>: Given the context 'In summary, the PCCN demonstration project was aimed to: 1) change the traditional patients' customs of freely choosing health care organizations and establish referral channels along the continuum of care, and 2) establish partnerships among the primary care clinics and hospitals to provide a continuum of health care services.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patients]
<Options>: A: cancer
B: probles
C: goes
D: human (aka homo sapiens)
E: mus <genus> (mice (aka mus <genus>))
F: None of the above. | [D] |
<Instruct>: Given the context 'It was also expected to establish the primary care system of family physicians to provide whole-people health care and improve care quality [1].
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [people]
<Options>: A: human (aka homo sapiens)
B: genus
C: this
D: animals (aka metazoa)
E: suborder
F: None of the above. | [A] |
<Instruct>: Given the context 'All the clinic physicians in a PCCN are assigned the roles of "family physicians" or "gatekeepers" who recruit people from the local community, keep background and medical files on them, certify family physician education training programs, and hold office hours in the member hospital, where they serve as joint faculty members for further medical consultations or medical utilizations of labs and tests, if necessary.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [people]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: psyche
C: kingdom
D: birds (aka aves)
E: family
F: None of the above. | [A] |
<Instruct>: Given the context 'Furthermore, this new demonstration model tries to minimize the barriers to patient access by setting up 24-hour a day, 7-day a week medical consultation telephone lines for providing urgent services onsite and for taking care of the patients whose family physicians' practices are closed to assure seamless care channels.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient; patients]
<Options>: A: humans (aka homo)
B: probles
C: homo sapiens (human) (aka homo sapiens)
D: mus <genus> (mice (aka mus <genus>))
E: theraps
F: aides
G: goes
H: isolate
I: None of the above. | [C; C] |
<Instruct>: Given the context 'Furthermore, this new demonstration model tries to minimize the barriers to patient access by setting up 24-hour a day, 7-day a week medical consultation telephone lines for providing urgent services onsite and for taking care of the patients whose family physicians' practices are closed to assure seamless care channels.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient; patients]
<Options>: A: subsection
B: humans (aka homo)
C: human (aka homo sapiens)
D: aides
E: circe
F: theraps
G: data
H: species
I: None of the above. | [C; C] |
<Instruct>: Given the context 'Then, guided by the goals and missions of the organization, top managers shape the design of the organization, including structural forms, information system, technology, human resources, organizational culture, and inter-organizational linkages, to achieve the final organizational performance.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: genus
B: primate (aka primates)
C: species
D: mammals (aka mammalia)
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'Borrowing the ideas of strategic contingency perspective [8,15,19] and top management model [14], it could be imply that success (organization performance) in reengineering a network lies in the integration of process and services (see Figure 1), including leadership/governing structure, teamwork between disciplines and patient care, financial planning, and information systems, characterized as the constructs of governance, clinical, financial, and information infrastructures, respectively, in this study.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: subsection
C: goes
D: data
E: proxys
F: None of the above. | [A] |
<Instruct>: Given the context 'In addition, another construct, marketing infrastructure, was especially important and designed to explore for PCCNs in this study because of patients' freedom of making healthcare choice and the traditional fragmented health care systems by individual health care organizations in Taiwan.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patients]
<Options>: A: cancer
B: homo sapiens (human) (aka homo sapiens)
C: mus <genus> (mice (aka mus <genus>))
D: subsection
E: aides
F: None of the above. | [B] |
<Instruct>: Given the context 'One major reason for Taiwan people's hospital shopping preferences was that Taiwan people usually believe the bigger the facility, the better capacities a facility has no matter on any aspect from medical professionals to tangible medical equipment and plants.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [people]
<Options>: A: suborder
B: this
C: animals (aka metazoa)
D: homo sapiens (human) (aka homo sapiens)
E: psyche
F: None of the above. | [D] |
<Instruct>: Given the context 'Governance or administrative integration infrastructure in establishing network partnerships refers to administrative structures (or responsibilities) created to facilitate communication, clear lines of authority, accountability, and responsibility for patient care services; to negotiate budgets and financial trade-offs; and to present a cohesive, consistent message in interactions with external agencies and the community [29,39-41] and most important for members in contract agreements, to manage participation', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: this
B: human (aka homo sapiens)
C: humans (aka homo)
D: subsection
E: genus
F: None of the above. | [B] |
<Instruct>: Given the context 'The purpose of care integration is to work directly with patients and their families over time to help them arrange and manage the complex resources that patients may need to maintain health and independent functioning.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patients]
<Options>: A: mouse (aka mus musculus)
B: homo (humans) (aka homo)
C: cancer
D: genus
E: human (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'At the same time, care integration is used to achieve the most cost-effective use possible of scarce resources, by steering patients to the health, social, and support services most appropriate for them at a given time [29].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patients]
<Options>: A: cancer
B: this
C: other (aka unidentified)
D: probles
E: human (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'Conrad and Dowling [33] pointed out that to coordinate and integrate patient care relies on connecting patient services at the different stages of the patient care processes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: human (aka homo sapiens)
B: aides
C: species
D: goes
E: other (aka unidentified)
F: None of the above. | [A] |
<Instruct>: Given the context 'The issues of clinical integration in the PCCNs could include [48-50]:
• planning and differentiating target markets based on the clinical services of the network members
• uniting individual clinical professionals for clinical project planning
• designing patient-centered care or case management teams
• establishing committees responsible for patient-centered case report meetings, case referral, transfer, and tracing, file management (record and information exchanges), clinical quality management (quality assurance, improvement, risk and malpractice management, and utilization review), and medical continuing education and on-job education.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: theraps
B: other (aka unidentified)
C: homo sapiens (human) (aka homo sapiens)
D: proxys
E: isolate
F: None of the above. | [C] |
<Instruct>: Given the context 'The issues of clinical integration in the PCCNs could include [48-50]:
• planning and differentiating target markets based on the clinical services of the network members
• uniting individual clinical professionals for clinical project planning
• designing patient-centered care or case management teams
• establishing committees responsible for patient-centered case report meetings, case referral, transfer, and tracing, file management (record and information exchanges), clinical quality management (quality assurance, improvement, risk and malpractice management, and utilization review), and medical continuing education and on-job education.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: other (aka unidentified)
B: proxys
C: isolate
D: theraps
E: None of the above. | [E] |
<Instruct>: Given the context 'Marketing infrastructure
Marketing integration refers to how to work together as a whole both from the provider and patient perspectives.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: genus
B: human (aka homo sapiens)
C: humans (aka homo)
D: mouse (aka mus musculus)
E: cancer
F: None of the above. | [B] |
<Instruct>: Given the context 'In a health care network with several organizational members and target patients, the marketing infrastructure in PCCNs here refers to provider members' marketing, meaning the resource sharing and market development in a PCCN as a whole.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patients]
<Options>: A: species
B: cancer
C: this
D: theraps
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'Some studies have argued that the quality of information systems can drive costs down, because a good information system can give physicians easy electronic access to complete the documentation of the patients' clinical records, better inform them about reimbursement and capitation issues, help them easily associate and manage cases together, and achieve a higher level of professional satisfaction [57,58].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patients]
<Options>: A: circe
B: cancer
C: kingdom
D: homo sapiens (human) (aka homo sapiens)
E: other (aka unidentified)
F: None of the above. | [D] |
<Instruct>: Given the context 'The issues of information coordination include [60-68]:
• establishing an electronic medical record system, regional information network for patient clinical and administrative data, clinical service arrangements and administrative work
• uniting the system information management and web pages.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: genus
B: isolate
C: aides
D: human (aka homo sapiens)
E: mouse (aka mus musculus)
F: None of the above. | [D] |
<Instruct>: Given the context 'Profiling the partnerships in Taiwan PCCNs: clinical infrastructure
Examining the extent of clinical infrastructure for network members, establishing two-directed patient referral systems and patient referral information files (Table 3, items 35 & 37) and uniting medical continuing education and on-job education (Table 3, item 34) were shown at a highly implemented rate in clinic-clinic (more than 70%) and clinic-hospital (more than 80%) relationships.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: probles
B: kingdom
C: data
D: human (aka homo sapiens)
E: circe
F: None of the above. | [D] |
<Instruct>: Given the context 'On the other hand, network members had higher percentages (more than 40%) not to think about the possible integration mechanisms including establishing committees to deal with medical malpractice (Table 3, item 44), planning and differentiating clinical market areas (Table 3, item 20), and designing patient-centered case management teams (Table 3, item 22).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: human (aka homo sapiens)
B: goes
C: this
D: species
E: theraps
F: None of the above. | [A] |
<Instruct>: Given the context 'The greatest integration was found in electronic patient records (Table 6: item 78), followed by information integration for patient data (Table 6: item 79) and clinical service arrangements (Table 6: item 81).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: mouse (aka mus musculus)
B: genus
C: species
D: human (aka homo sapiens)
E: this
F: None of the above. | [D] |
<Instruct>: Given the context 'In this study, it was found a low level of involvement of medical teams in medical projects, patient-centered case management, and case report meetings among the network members (Table 3: item 21, 22, and 23) from a clinical integration perspective.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: this
B: human (aka homo sapiens)
C: other (aka unidentified)
D: humans (aka homo)
E: mouse (aka mus musculus)
F: None of the above. | [B] |
<Instruct>: Given the context 'Several researchers have addressed that clinical integration providing a process of medical management, care management, case management, and patient management designed to transform the traditionally fragmented delivery system into a more cohesive system [71], and lead to higher service quality and assure financial objectives [72,73].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: circe
C: proxys
D: goes
E: genus
F: None of the above. | [A] |
<Instruct>: Given the context 'Generally speaking, hospitals have more resources (i.e., money, human resources, materials, and physical assets) than clinics, which might explain the stronger marketing involvements between the clinic and hospital members, including the library sharing (books and literatures), facility brochure dissemination, public promoting, and medical research cooperation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: avian (aka aves)
B: this
C: macrobiotus sapiens
D: human (aka homo sapiens)
E: mammals (aka mammalia)
F: None of the above. | [D] |
<Instruct>: Given the context 'Generally speaking, hospitals have more resources (i.e., money, human resources, materials, and physical assets) than clinics, which might explain the stronger marketing involvements between the clinic and hospital members, including the library sharing (books and literatures), facility brochure dissemination, public promoting, and medical research cooperation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: macrobiotus sapiens
B: avian (aka aves)
C: this
D: mammals (aka mammalia)
E: None of the above. | [E] |
<Instruct>: Given the context 'Most of the clinics surveyed have focused more on the individual public members' administrative works such as filing patient medical records, collecting and managing network patient clinical data, and scheduling clinical services, which were required by the BNHI.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: probles
B: other (aka unidentified)
C: cancer
D: human (aka homo sapiens)
E: proxys
F: None of the above. | [D] |
<Instruct>: Given the context 'It suggests that the network partners might be engaged, firstly, more in simpler network cooperation such as the administrative systems for patient admission to the network members and establishing united web pages for patients to access their family physicians and network members for medical and public promotion purposes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient; patients]
<Options>: A: other (aka unidentified)
B: humans (aka homo)
C: goes
D: cancer
E: circe
F: homo sapiens (human) (aka homo sapiens)
G: species
H: None of the above. | [F; F] |
<Instruct>: Given the context 'It suggests that the network partners might be engaged, firstly, more in simpler network cooperation such as the administrative systems for patient admission to the network members and establishing united web pages for patients to access their family physicians and network members for medical and public promotion purposes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient; patients]
<Options>: A: human (aka homo sapiens)
B: genus
C: probles
D: subsection
E: species
F: mouse (aka mus musculus)
G: goes
H: this
I: mus <genus> (mice (aka mus <genus>))
J: None of the above. | [A; A] |
<Instruct>: Given the context 'Conclusion
This study tried to portray and trace how the facility participants were involved in the Taiwan PCCNs.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [participants]
<Options>: A: homo (humans) (aka homo)
B: athletes
C: human (aka homo sapiens)
D: test organism
E: species
F: None of the above. | [C] |
<Instruct>: Given the context 'Some participants in the PCCNs may simply seek short-term economic gains and have little interest in joint learning and continuous improvement.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [participants]
<Options>: A: human (aka homo sapiens)
B: other (aka unidentified)
C: test organism
D: species
E: kingdom
F: None of the above. | [A] |
<Instruct>: Given the context 'In addition to the macro concepts including governance, clinical, marketing, financial, and information infrastructures explored in this study, other managerial issues for integrated organizations were also suggested such as formation of an integrated cultural atmosphere, human resources management, physician involvement, mission and commitment establishment, from micro organizational behavior perspective', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: suborder
B: species
C: primate (aka primates)
D: homo sapiens (human) (aka homo sapiens)
E: genus
F: None of the above. | [D] |
<Instruct>: Given the context 'Our results show, for the first time, that the p53β isoform is the only p53 species to be endogenously expressed in the human NB cell line SK-N-AS, suggesting that the C-terminus truncated p53 isoforms may play an important role in NB tumor development.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: macrobiotus sapiens
B: homo sapiens (human) (aka homo sapiens)
C: this
D: placental mammals (aka eutheria)
E: probles
F: None of the above. | [B] |
<Instruct>: Given the context 'The p53 tumor suppressor gene remains the most frequently altered gene in human tumors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: mammals (aka mammalia)
C: this
D: genus
E: birds (aka aves)
F: None of the above. | [A] |
<Instruct>: Given the context 'The p53 tumor suppressor gene remains the most frequently altered gene in human tumors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: this
B: mammals (aka mammalia)
C: genus
D: birds (aka aves)
E: None of the above. | [E] |
<Instruct>: Given the context 'In general, the majority of p53 mutations in human neoplasia are missense mutations affecting the DNA-binding domain (DBD).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: primate (aka primates)
B: macrobiotus sapiens
C: human (aka homo sapiens)
D: animals (aka metazoa)
E: eutherian mammals (aka eutheria)
F: None of the above. | [C] |
<Instruct>: Given the context 'Unlike other human cancers, p53 in neuroblastoma (NB) is rarely mutated in the primary tumor at diagnosis but high levels of wild-type p53 (wt p53) protein expression have been found in the cytoplasm of undifferentiated tumors (5,6).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: species
B: macrobiotus sapiens
C: mammals (aka mammalia)
D: genus
E: human (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'p53 mutations are unusual in human NB', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: primate (aka primates)
B: suborder
C: biota (aka cellular organisms)
D: human (aka homo sapiens)
E: animals (aka metazoa)
F: None of the above. | [D] |
<Instruct>: Given the context 'In this respect, Tweddle et al. (10) described how two NB cell lines derived from the same patient can elicit a different p53 status: wt p53 for SK-N-BE(1a) established before treatment, and mutated p53 for SK-N-BE(2c) established after relapse of the patient under treatment with cytotoxic agents such as cyclophosphamide, doxorubicin, vincristine and radiotherapy.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: human (aka homo sapiens)
B: humans (aka homo)
C: subsection
D: kingdom
E: proxys
F: None of the above. | [A] |
<Instruct>: Given the context 'By analyzing IGR-N-91, a cell line established in our laboratory from the bone marrow of a patient with metastatic NB after unsuccessful Adriamycin–vincristine chemotherapy (12), we identified another type of aberrant protein that arises from the duplication of exons 7-8-9.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: proxys
C: kingdom
D: data
E: isolate
F: None of the above. | [A] |
<Instruct>: Given the context 'In the present study we report two novel p53 C-terminus mutants identified in SK-N-AS and IGR-NB8 human NB cell lines.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: human (aka homo sapiens)
B: this
C: primate (aka primates)
D: humans (aka homo)
E: cellular organisms (biota) (aka cellular organisms)
F: None of the above. | [A] |
<Instruct>: Given the context 'The biological properties of these two new variants were analyzed in comparison with p53 isolated from six other human NB lines: three [LAN-1, SK-N-BE(2) and IGR-N-91] expressing mutant p53 and three (SH-SY5Y, LAN-5 and IMR-32) expressing the wt protein.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: eutherian mammals (aka eutheria)
B: suborder
C: macrobiotus sapiens
D: genus
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'This characterization was done by using a range of functional assays: (i) the ability of the protein to bind with p53 consensus sequence using the functional analysis of separated allele in yeast (FASAY); (ii) the ability of the protein to transactivate the p53-responsive element (RE) identified either in the promoter of p21/WAF1 or in the first intron of BAX, using luciferase reporter assay; (iii) the induction of endogenous p21/WAF1 gene expression under stress conditions.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [yeast]
<Options>: A: saccharomyces lactis (aka kluyveromyces lactis)
B: saccharomyces cf. cerevisiae/paradoxus (saccharomyces cerevisiae or paradoxus) (aka saccharomyces cf. cerevisiae/paradoxus)
C: mycoderma cerevisiae (aka saccharomyces cerevisiae)
D: candida/saccharomycetales (aka candida/saccharomycales clade)
E: saccharomyceta
F: None of the above. | [C] |
<Instruct>: Given the context 'MATERIALS AND METHODS
Neuroblastoma cell lines, culture and drug treatments
The parental human NB SH-SY5Y, SK-N-AS, IMR-32 and SK-N-BE(2) cell lines were purchased from the European Collection of Cell Cultures (ECACC, Wiltshire, UK).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: this
B: homo (humans) (aka homo)
C: human (aka homo sapiens)
D: species
E: biota (aka cellular organisms)
F: None of the above. | [C] |
<Instruct>: Given the context 'The human IGR-NB8 cells (a gift of Prof. Gilles Vassal, UPRES EA 3535, Institut Gustave Roussy, Villejuif) were derived from a previously untreated localized NB (14).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: genus
C: primate (aka primates)
D: biota (aka cellular organisms)
E: avian (aka aves)
F: None of the above. | [A] |
<Instruct>: Given the context 'The human IGR-NB8 cells (a gift of Prof. Gilles Vassal, UPRES EA 3535, Institut Gustave Roussy, Villejuif) were derived from a previously untreated localized NB (14).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: primate (aka primates)
B: biota (aka cellular organisms)
C: genus
D: avian (aka aves)
E: None of the above. | [E] |
<Instruct>: Given the context 'The human IGR-N-91 cell line was established in our laboratory from the bone marrow of a patient with metastatic NB after unsuccessful adriamycin–vincristin chemotherapy (12).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human; patient]
<Options>: A: other (aka unidentified)
B: eutherian mammals (aka eutheria)
C: humans (aka homo)
D: homo sapiens (human) (aka homo sapiens)
E: this
F: genus
G: cancer
H: kingdom
I: None of the above. | [D; D] |
<Instruct>: Given the context 'The human IGR-N-91 cell line was established in our laboratory from the bone marrow of a patient with metastatic NB after unsuccessful adriamycin–vincristin chemotherapy (12).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human; patient]
<Options>: A: theraps
B: suborder
C: primate (aka primates)
D: mammals (aka mammalia)
E: human (aka homo sapiens)
F: cancer
G: genus
H: kingdom
I: avian (aka aves)
J: None of the above. | [E; E] |
<Instruct>: Given the context 'Fluorescent in situ hybridization (FISH)
Cytogenetic preparations
Metaphase spreads from healthy human male lymphocytes and tumor cell lines were prepared as described previously (19).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: human (aka homo sapiens)
B: cellular organisms (biota) (aka cellular organisms)
C: kingdom
D: animals (aka metazoa)
E: mammals (aka mammalia)
F: None of the above. | [A] |
<Instruct>: Given the context 'Functional assay in yeast
cDNA was obtained by RT of 1 μg of total RNA using Superscript II™ RNase H-Reverse transcriptase (Invitrogen) and random hexamers to prime the synthesis in conditions specified by the manufacturer.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [yeast]
<Options>: A: budding yeasts & others (aka saccharomycotina)
B: candida/saccharomycetales (aka candida/saccharomycales clade)
C: saccharomyces sp.
D: brewer's yeast (aka saccharomyces cerevisiae)
E: saccharomyces cf. cerevisiae
F: None of the above. | [D] |
<Instruct>: Given the context 'p53 cDNA was amplified by PCR and cotransformed into yeast, IG397 Ade2 strain, together with either pRDI-22 vector for p53-standard assay or pFW35 and pFW34 plasmid for 5′ or 3′ split assay, respectively, carrying the ADE2 open reading frame under the control of a p53-responsive promoter (20).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [yeast]
<Options>: A: saccharomyceta
B: saccharomyces cf. cerevisiae
C: candida/saccharomycetales (aka candida/saccharomycales clade)
D: baker's yeast (aka saccharomyces cerevisiae)
E: saccharomyces sp.
F: None of the above. | [D] |
<Instruct>: Given the context 'The p53 protein expressed in SK-N-AS is the p53β isoform
An alternatively spliced form of human p53 mRNA with an additional 133 bp exon derived from intron 9 has been detected in normal human lymphocytes (15).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: mammals (aka mammalia)
B: primate (aka primates)
C: human (aka homo sapiens)
D: suborder
E: humans (aka homo)
F: None of the above. | [C] |
<Instruct>: Given the context 'A yeast functional assay confirmed the absence of p53 full-length expression in SK-N-AS and IGR-NB8
It is possible to detect p53 mutation using a simple yeast colony color assay as described by Flaman et al. (23).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [yeast]
<Options>: A: saccharomyces sp.
B: saccharomycotina (budding yeasts & others) (aka saccharomycotina)
C: saccharomyces cerevisiae x saccharomyces mikatae
D: saccharomyceta
E: saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883) (aka saccharomyces cerevisiae)
F: None of the above. | [E] |
<Instruct>: Given the context 'In the IGR-N-91 cell line, where p53 harbors two contiguous sets of exons 7–9, spanning the DBD and oligomerization domain, it is interesting to note that the yeast colonies were predominantly white (Figure 4B, dish b) with the split 5′ and the split 3′ assay (96 and 87% of white colonies, respectively)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [yeast]
<Options>: A: saccharomyces cf. cerevisiae/paradoxus (saccharomyces cerevisiae or paradoxus) (aka saccharomyces cf. cerevisiae/paradoxus)
B: brewer's yeast (aka saccharomyces cerevisiae)
C: saccharomyces lactis (aka kluyveromyces lactis)
D: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
E: candida/saccharomycetales (aka candida/saccharomycales clade)
F: None of the above. | [B] |
<Instruct>: Given the context 'In the IGR-N-91 cell line, where p53 harbors two contiguous sets of exons 7–9, spanning the DBD and oligomerization domain, it is interesting to note that the yeast colonies were predominantly white (Figure 4B, dish b) with the split 5′ and the split 3′ assay (96 and 87% of white colonies, respectively)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [yeast]
<Options>: A: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
B: saccharomyces cf. cerevisiae/paradoxus (saccharomyces cerevisiae or paradoxus) (aka saccharomyces cf. cerevisiae/paradoxus)
C: candida/saccharomycetales (aka candida/saccharomycales clade)
D: saccharomyces lactis (aka kluyveromyces lactis)
E: None of the above. | [E] |
<Instruct>: Given the context 'The p53RE located within either the human p21/WAF1 promoter or the intron 1 of the mouse and human BAX gene [(18) and D. Munsch, personnal communication) were cloned in a luciferase reporter gene plasmid upstream of the E1B minimal promoter as described in Materials and Methods.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human; mouse]
<Options>: A: mice (aka mus sp.) (aka mus sp.)
B: homo sapiens (human) (aka homo sapiens)
C: avian (aka aves)
D: mus domesticus (aka mus musculus domesticus)
E: eutherian mammals (aka eutheria)
F: mus musculus (house mouse) (aka mus musculus)
G: macrobiotus sapiens
H: suborder
I: eastern european house mouse (aka mus musculus musculus)
J: mouse (aka mus <genus>)
K: None of the above. | [B; F] |
<Instruct>: Given the context 'The p53RE located within either the human p21/WAF1 promoter or the intron 1 of the mouse and human BAX gene [(18) and D. Munsch, personnal communication) were cloned in a luciferase reporter gene plasmid upstream of the E1B minimal promoter as described in Materials and Methods.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human; mouse]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: genus
C: mus domesticus (aka mus musculus domesticus)
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: macrobiotus sapiens
F: placental mammals (aka eutheria)
G: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
H: house mouse (aka mus musculus)
I: this
J: mus cricetus (aka cricetus cricetus)
K: None of the above. | [A; H] |
<Instruct>: Given the context 'The p53 gene, the ‘genome guardian’, is mutated in over 50% of human cancers, with the most common mutations being missense mutations (>2/3 of mutations) (26).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: mammals (aka mammalia)
B: macrobiotus sapiens
C: animals (aka metazoa)
D: species
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'In human neuroblastoma tumors, p53 mutations are rarely present at the time of diagnosis (5,27); however, oncogenic p53 mutations can be found in advanced neuroblastomas that often relapse following high-dose chemotherapy (10).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: human (aka homo sapiens)
B: eutherian mammals (aka eutheria)
C: primate (aka primates)
D: macrobiotus sapiens
E: kingdom
F: None of the above. | [A] |
<Instruct>: Given the context 'An investigation into the p53 genomic status and functions of eight human NB lines revealed that all five of the mutated cell lines had distinct genetic characteristics as is schematically represented in Figure 9: SK-N-BE(2) with a single missense mutation in the p53 gene, encoding a highly stable full-length protein.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: animals (aka metazoa)
B: species
C: macrobiotus sapiens
D: homo sapiens (human) (aka homo sapiens)
E: avian (aka aves)
F: None of the above. | [D] |
<Instruct>: Given the context 'Peculiarities of carcinogenesis under simultaneous oral administration of benzo(a)pyrene and o-cresol in mice.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus sp. (mice (aka mus sp.))
C: mus castaneus (aka mus musculus castaneus)
D: peromyscus
E: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
F: None of the above. | [A] |
<Instruct>: Given the context 'Abstract
A modifying influence of ortho-cresol (o-cresol) on the carcinogenic effect of benzo(a)pyrene (BaP) with combined oral administration to CC57Br mice had been found.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: eastern european house mouse (aka mus musculus musculus)
B: peromyscus
C: mus sp. (mice (aka mus sp.))
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Environnmental Health Perspectives Supplements Vol. 101 (Suppl. 3): 341-344 (1993)
Peculiarities of Carcinogenesis under Simultaneous Oral Administration of
Benzo(a)Pyrene and o-Cresol in Mice
by N. Ya.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mice (aka mus sp.) (aka mus sp.)
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: mus castaneus (aka mus musculus castaneus)
D: mouse (aka mus <genus>)
E: house mouse (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Environnmental Health Perspectives Supplements Vol. 101 (Suppl. 3): 341-344 (1993)
Peculiarities of Carcinogenesis under Simultaneous Oral Administration of
Benzo(a)Pyrene and o-Cresol in Mice
by N. Ya.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mice (aka mus sp.) (aka mus sp.)
B: mus castaneus (aka mus musculus castaneus)
C: mouse (aka mus <genus>)
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: None of the above. | [E] |
<Instruct>: Given the context 'A modifying influence of ortho-cresol (o-cresol) on the carcinogenic effect of benzo(a)pyrene (BaP) with combined oral administration to CC57Br mice had been found.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
D: mus castaneus (aka mus musculus castaneus)
E: peromyscus
F: None of the above. | [A] |
<Instruct>: Given the context 'The maximal enhancing effect was observed after BaP (2.5 mg) and NO2 (0.87 mg/m3) were exposed to rat respiratory tract.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rat]
<Options>: A: rattus rattoides (aka rattus pyctoris)
B: rattus sp. (rats (aka rattus sp.))
C: rattus norvegicus albus
D: house rat (aka rattus rattus)
E: brown rat (aka rattus norvegicus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Phenol at 1 mg orally to CC57Br mice enhanced the BaP (1 mg) effect, but no effect was seen at 0.02 mg.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus musculus (house mouse) (aka mus musculus)
D: mus <subgenus> (mus (aka mus <subgenus>))
E: mice (aka mus <genus>) (aka mus <genus>)
F: None of the above. | [C] |
<Instruct>: Given the context 'This report presents the results of combined oral administration of BaP and artho-cresol (o-cresol) in mice,
'Ukrainian State Medical Center for Environmental Health, Kiev, Ukraine.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: mus <subgenus> (mus (aka mus <subgenus>))
C: mus sp. (mice (aka mus sp.))
D: mus cricetus (aka cricetus cricetus)
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Materials and Methods
The experiment was conducted on CC57Br female mice weighing 12-14 g. Animals were divided in 15 groups.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mouse (aka mus <genus>)
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mus cricetus (aka cricetus cricetus)
D: mouse (aka mus musculus)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [D] |
<Instruct>: Given the context 'One hundred percent of the mice that received 5 mg of BaP alone had tumors.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus castaneus (aka mus musculus castaneus)
B: mus musculus (house mouse) (aka mus musculus)
C: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: peromyscus
F: None of the above. | [B] |
<Instruct>: Given the context 'Shortening of the time to appearance of malignant tumors was also observed: the mice with forestomach cancer died between 23 and 26.2 weeks after the beginning of experiment, but the controls survived to 58.5 weeks.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus domesticus (aka mus musculus domesticus)
B: mus cricetus (aka cricetus cricetus)
C: mus musculus (house mouse) (aka mus musculus)
D: eastern european house mouse (aka mus musculus musculus)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [C] |
<Instruct>: Given the context 'Muliple small metastases in the lungs and mediastinum were found in 42.8% of mice, which signifies a high degree of malignancy.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: house mouse (aka mus musculus)
B: mus castaneus (aka mus musculus castaneus)
C: mice (aka mus sp.) (aka mus sp.)
D: mus <subgenus> (mus (aka mus <subgenus>))
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | [A] |
<Instruct>: Given the context 'Besides the quantitative aspects, other peculiarities of carcinogenesis in mice simultaneously administered BaP and o-cresol should be noted.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: mus musculus (house mouse) (aka mus musculus)
C: mus domesticus (aka mus musculus domesticus)
D: mus sp. (mice (aka mus sp.))
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | [B] |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.