instruction stringlengths 161 2.29k | input stringlengths 80 650 | response stringclasses 6 values |
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<Instruct>: Given the context 'P Ic .55, we digested phage DNA with EcoRI and BamHI, ligated the digestion products into similarly digested pBR322, and transformed the ligation mixture into E. coli K336.', select the correct biomedical concept corresponding to 'e. coli'. Answer using one of the provided options. | <Options>: A: escherichia coli b (escherichia coli (strain b)) (aka escherichia coli b)
B: enterobacteria (aka enterobacteriaceae)
C: prokaryotes (aka bacteria)
D: escherichia
E: bacillus coli (aka escherichia coli)
F: None of the above. | E |
<Instruct>: Given the context 'The plasmids were carried by E. coli K336.', select the correct biomedical concept corresponding to 'e. coli'. Answer using one of the provided options. | <Options>: A: enterobacteria (aka enterobacteriaceae)
B: e. coli (aka escherichia coli)
C: escherichia coli k12 (aka escherichia coli k-12)
D: unspecified coliform bacterium
E: escherichia
F: None of the above. | B |
<Instruct>: Given the context 'E. coli W1485(pFA02) was mated with the F- strain MX648 and subsequently plated on ampicillin (to select for the plasmid) and streptomycin sulfate (to select for the recipient strain).', select the correct biomedical concept corresponding to 'e. coli'. Answer using one of the provided options. | <Options>: A: escherichia coli (escherichia/shigella coli) (aka escherichia coli)
B: escherichia
C: enterobacteriales (aka enterobacterales)
D: enterobacteria (aka enterobacteriaceae)
E: prokaryotes (aka bacteria)
F: None of the above. | A |
<Instruct>: Given the context 'MUC1 alters oncogenic events and transcription in human breast cancer cells
Abstract
Introduction
MUC1 is an oncoprotein whose overexpression correlates with aggressiveness of tumors and poor survival of cancer patients.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: animals (aka metazoa)
B: humans (aka homo)
C: homo sapiens (human) (aka homo sapiens)
D: kingdom
E: genus
F: None of the above. | C |
<Instruct>: Given the context 'MUC1 alters oncogenic events and transcription in human breast cancer cells
Abstract
Introduction
MUC1 is an oncoprotein whose overexpression correlates with aggressiveness of tumors and poor survival of cancer patients.', select the correct biomedical concept corresponding to 'patients'. Answer using one of the provided options. | <Options>: A: other (aka unidentified)
B: human (aka homo sapiens)
C: theraps
D: genus
E: cancer
F: None of the above. | B |
<Instruct>: Given the context 'Mouse studies have been integral to the current understanding of MUC1 in cancer.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: mus molossinus (aka mus musculus molossinus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mouse (aka mus musculus)
E: mus sp. (mice (aka mus sp.))
F: None of the above. | D |
<Instruct>: Given the context 'Muc1 knockout mice (Muc1-/-; MUC1 is human; Muc1 is mouse)', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus (aka mus <subgenus>) (aka mus <subgenus>)
B: mice (aka mus <genus>) (aka mus <genus>)
C: peromyscus
D: mouse (aka mus musculus)
E: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
F: None of the above. | D |
<Instruct>: Given the context 'Muc1 knockout mice (Muc1-/-; MUC1 is human; Muc1 is mouse)', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: suborder
B: species
C: mammals (aka mammalia)
D: homo sapiens (human) (aka homo sapiens)
E: probles
F: None of the above. | D |
<Instruct>: Given the context 'Muc1 knockout mice (Muc1-/-; MUC1 is human; Muc1 is mouse)', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: species
B: kingdom
C: avian (aka aves)
D: eutherian mammals (aka eutheria)
E: this
F: None of the above. | F |
<Instruct>: Given the context 'Muc1 knockout mice (Muc1-/-; MUC1 is human; Muc1 is mouse)', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mus molossinus (aka mus musculus molossinus)
B: peromyscus
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: mice (aka mus sp.) (aka mus sp.)
E: mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'show a reduction in tumorigenic phenotype when crossed onto mice overexpressing the Wnt-1', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: mus cricetus (aka cricetus cricetus)
C: eastern european house mouse (aka mus musculus musculus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus domesticus (aka mus musculus domesticus)
F: None of the above. | A |
<Instruct>: Given the context 'Materials and methods
Cell culture and siRNA transfection
MDA-MB-468 and BT-20 cells (American Type Culture Collection) were cultured in Dulbecco's modified Eagle's medium (Invitrogen, Carlsbad, CA, USA) plus 10% fetal calf serum, 1% Glutamax (Invitrogen) and 1% penicillin/streptomycin.', select the correct biomedical concept corresponding to 'calf'. Answer using one of the provided options. | <Options>: A: bos bovis (aka bos taurus)
B: sueus
C: mus spretus (mus musculus spretus) (aka mus spretus)
D: horse (aka equus caballus)
E: bovidae
F: None of the above. | A |
<Instruct>: Given the context 'Non-commercial antibodies used were: BC2, a mouse monoclonal to the MUC1-EX (gift of Dr McGuckin, Queensland University, Queensland, Australia), and CT2, an Armenian hamster monoclonal to the MUC1-CT developed in our lab', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
B: peromyscus
C: mouse (aka mus musculus)
D: mus molossinus (aka mus musculus molossinus)
E: mouse (aka mus <genus>)
F: None of the above. | C |
<Instruct>: Given the context 'Non-commercial antibodies used were: BC2, a mouse monoclonal to the MUC1-EX (gift of Dr McGuckin, Queensland University, Queensland, Australia), and CT2, an Armenian hamster monoclonal to the MUC1-CT developed in our lab', select the correct biomedical concept corresponding to 'armenian hamster'. Answer using one of the provided options. | <Options>: A: desert hamster (aka phodopus roborovskii)
B: cricetus cricetus (black-bellied hamster) (aka cricetus cricetus)
C: gansu hamster (aka cansumys canus)
D: gray dwarf hamster (aka nothocricetulus migratorius)
E: romanian hamster (aka mesocricetus newtoni)
F: None of the above. | D |
<Instruct>: Given the context 'Following washing and 2 minute's incubation with 0.1 M Tris to neutralize the acid, cells were re-suspended in FACS buffer (0.5% fetal calf serum in PBS) and stained with Phycoerythrin (PE)-conjugated anti-BrdU according to the manufacturer's protocol for flow cytometry analysis on a FACScan instrument.
', select the correct biomedical concept corresponding to 'calf'. Answer using one of the provided options. | <Options>: A: equus subg. equus (aka equus)
B: bovine (aka bos taurus)
C: sueus
D: horse (aka equus caballus)
E: boveria
F: None of the above. | B |
<Instruct>: Given the context 'Two human breast cancer cell lines, MDA-MB-468 and BT-20, were transiently transfected with a pool of four siRNA oligonucleotides directed against the MUC1 mRNA (468.siMUC1 and BT.siMUC1), or a control oligonucleotide directed against luciferase (468.siLuc and BT.siLuc).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: animals (aka metazoa)
B: homo (humans) (aka homo)
C: genus
D: human (aka homo sapiens)
E: species
F: None of the above. | D |
<Instruct>: Given the context 'This result disagrees with MUC1 activation of the AKT pathway in rat 3Y1 cells [18], and may reflect regulation more appropriate to breast cancer cells; this is supported by activation of AKT in response to MUC1 siRNA in other lines [21].', select the correct biomedical concept corresponding to 'rat'. Answer using one of the provided options. | <Options>: A: rats (aka rattus norvegicus) (aka rattus norvegicus)
B: rattus sp. (rats (aka rattus sp.))
C: rat (aka rattus) (aka rattus)
D: rattus norvegicus albus
E: house rat (aka rattus rattus)
F: None of the above. | F |
<Instruct>: Given the context 'Interestingly, 468.siMUC1 cells display somewhat decreased invasion on collagen IV, laminin, and fibronectin matrices, and on a no-matrix control (Figure 5c), which is in agreement with the trend towards decreased metastasis observed in Muc1-/- × MMTV-PyV MT mice [8].
', select the correct biomedical concept corresponding to 'mmtv'. Answer using one of the provided options. | <Options>: A: murine non-leukeminogenic retrovirus
B: mouse mammary tumor virus (strain gr)
C: mlv (aka murine leukemia virus) (aka murine leukemia virus)
D: mouse mammary tumor virus mtv (aka mouse mammary tumor virus)
E: human mmtv-like retrovirus (aka human endogenous retrovirus k)
F: None of the above. | D |
<Instruct>: Given the context 'Interestingly, 468.siMUC1 cells display somewhat decreased invasion on collagen IV, laminin, and fibronectin matrices, and on a no-matrix control (Figure 5c), which is in agreement with the trend towards decreased metastasis observed in Muc1-/- × MMTV-PyV MT mice [8].
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: western european house mouse (aka mus musculus domesticus)
B: mus (aka mus <genus>) (aka mus <genus>)
C: peromyscus
D: mouse (aka mus musculus)
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | D |
<Instruct>: Given the context 'Interestingly, 468.siMUC1 cells display somewhat decreased invasion on collagen IV, laminin, and fibronectin matrices, and on a no-matrix control (Figure 5c), which is in agreement with the trend towards decreased metastasis observed in Muc1-/- × MMTV-PyV MT mice [8].
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: peromyscus
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: mus sp. (mice (aka mus sp.))
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | F |
<Instruct>: Given the context 'Discussion
This report describes both the transcriptional alterations seen after transfection with MUC1 siRNA in human breast cancer cells and the effects on events such as apoptosis and proliferation.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: placental mammals (aka eutheria)
B: primate (aka primates)
C: human (aka homo sapiens)
D: macrobiotus sapiens
E: this
F: None of the above. | C |
<Instruct>: Given the context 'Both lines have epithelial morphology, form tumors slowly in nude mice [37], have mutant p53 [39,40], express EGFR', select the correct biomedical concept corresponding to 'nude mice'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus molossinus (aka mus musculus molossinus)
C: neomys
D: delicate mouse (aka mus tenellus)
E: mus terricolor (earth-colored mouse) (aka mus terricolor)
F: None of the above. | A |
<Instruct>: Given the context 'First, though MMP-2 levels are increased in mouse mammary tumors, its expression is confined to the stroma', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mus <subgenus> (mus (aka mus <subgenus>))
B: mice (aka mus sp.) (aka mus sp.)
C: peromyscus
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: house mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Similarly, though MUC1 drives mammary oncogenesis in its own right [9] and facilitates tumorigenesis driven by other oncogenes [7,8], Muc1 is selectively down-regulated in c-neu-induced mouse mammary tumors', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: western european house mouse (aka mus musculus domesticus)
B: mus molossinus (aka mus musculus molossinus)
C: mice (aka mus sp.) (aka mus sp.)
D: mus <subgenus> (mus (aka mus <subgenus>))
E: house mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Molecular cloning of four novel murine ribonuclease genes: unusual expansion within the ribonuclease A gene family.
', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mouse (aka mus musculus)
B: mus cricetus (aka cricetus cricetus)
C: mus <genus> (mice (aka mus <genus>))
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus norvegicus (aka rattus norvegicus)
F: None of the above. | A |
<Instruct>: Given the context 'Abstract
We have characterized four novel murine ribonuclease genes that, together with the murine eosinophil-associated ribonucleases 1 and 2, form a distinct and unusual cluster within the RNase A gene superfamily.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: western european house mouse (aka mus musculus domesticus)
B: mus cricetus (aka cricetus cricetus)
C: mice (aka mus sp.) (aka mus sp.)
D: mus musculus (house mouse) (aka mus musculus)
E: mice (aka mus <genus>) (aka mus <genus>)
F: None of the above. | D |
<Instruct>: Given the context 'Abstract
We have characterized four novel murine ribonuclease genes that, together with the murine eosinophil-associated ribonucleases 1 and 2, form a distinct and unusual cluster within the RNase A gene superfamily.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus sp. (mice (aka mus sp.))
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus domesticus (aka mus musculus domesticus)
D: house mouse (aka mus musculus)
E: mus <subgenus> (mus (aka mus <subgenus>))
F: None of the above. | D |
<Instruct>: Given the context 'Although the amino acid sequence similarities among these murine ribonucleases varies from 60 to 94%, they form a unique cluster, as each sequence is found to be more closely related to another of this group than to either murine angiogenin or to murine pancreatic ribonuclease.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus <subgenus> (mus (aka mus <subgenus>))
B: mouse (aka mus <genus>)
C: mus norvegicus (aka rattus norvegicus)
D: western european house mouse (aka mus musculus domesticus)
E: mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Although the amino acid sequence similarities among these murine ribonucleases varies from 60 to 94%, they form a unique cluster, as each sequence is found to be more closely related to another of this group than to either murine angiogenin or to murine pancreatic ribonuclease.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus norvegicus (aka rattus norvegicus)
B: house mouse (aka mus musculus)
C: peromyscus
D: mus sp. (mice (aka mus sp.))
E: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
F: None of the above. | B |
<Instruct>: Given the context 'Although the amino acid sequence similarities among these murine ribonucleases varies from 60 to 94%, they form a unique cluster, as each sequence is found to be more closely related to another of this group than to either murine angiogenin or to murine pancreatic ribonuclease.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus sp. (mice (aka mus sp.))
C: mus (aka mus <genus>) (aka mus <genus>)
D: mus norvegicus (aka rattus norvegicus)
E: mus domesticus (aka mus musculus domesticus)
F: None of the above. | A |
<Instruct>: Given the context 'Although the amino acid sequence similarities among these murine ribonucleases varies from 60 to 94%, they form a unique cluster, as each sequence is found to be more closely related to another of this group than to either murine angiogenin or to murine pancreatic ribonuclease.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: mus cricetus (aka cricetus cricetus)
C: western european house mouse (aka mus musculus domesticus)
D: peromyscus
E: mice (aka mus <genus>) (aka mus <genus>)
F: None of the above. | F |
<Instruct>: Given the context '� 1997 Oxford University Press
Nucleic Acids Research, 1997, Vol. 25, No. 21
4235�4239
Molecular cloning of four novel murine ribonuclease genes: unusual expansion within the Ribonuclease A gene family Dean Batten+, Kimberly D. Dyer, Joseph B. Domachowske� and Helene F. Rosenberg*', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: peromyscus
B: mus cricetus (aka cricetus cricetus)
C: mouse (aka mus musculus)
D: mice (aka mus <genus>) (aka mus <genus>)
E: mus sp. (mice (aka mus sp.))
F: None of the above. | C |
<Instruct>: Given the context 'We have characterized four novel murine ribonuclease genes that, together with the murine eosinophilassociated ribonucleases 1 and 2, form a distinct and unusual cluster within the RNase A gene superfamily.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus norvegicus (aka rattus norvegicus)
B: mus musculus (house mouse) (aka mus musculus)
C: peromyscus
D: mus <subgenus> (mus (aka mus <subgenus>))
E: mouse (aka mus <genus>)
F: None of the above. | B |
<Instruct>: Given the context 'We have characterized four novel murine ribonuclease genes that, together with the murine eosinophilassociated ribonucleases 1 and 2, form a distinct and unusual cluster within the RNase A gene superfamily.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: house mouse (aka mus musculus)
C: mice (aka mus sp.) (aka mus sp.)
D: western european house mouse (aka mus musculus domesticus)
E: mus norvegicus (aka rattus norvegicus)
F: None of the above. | B |
<Instruct>: Given the context 'Although the amino acid sequence similarities among these murine ribonucleases varies from 60 to 94%, they form a unique cluster, as each sequence is found to be more closely related to another of this group than to either murine angiogenin or to murine pancreatic ribonuclease.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mouse (aka mus musculus)
B: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
C: mus <subgenus> (mus (aka mus <subgenus>))
D: mice (aka mus <genus>) (aka mus <genus>)
E: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
F: None of the above. | A |
<Instruct>: Given the context 'Although the amino acid sequence similarities among these murine ribonucleases varies from 60 to 94%, they form a unique cluster, as each sequence is found to be more closely related to another of this group than to either murine angiogenin or to murine pancreatic ribonuclease.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: peromyscus
C: mus sp. (mice (aka mus sp.))
D: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
E: mus <subgenus> (mus (aka mus <subgenus>))
F: None of the above. | A |
<Instruct>: Given the context 'Although the amino acid sequence similarities among these murine ribonucleases varies from 60 to 94%, they form a unique cluster, as each sequence is found to be more closely related to another of this group than to either murine angiogenin or to murine pancreatic ribonuclease.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus <subgenus> (mus (aka mus <subgenus>))
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus musculus (house mouse) (aka mus musculus)
D: mice (aka mus sp.) (aka mus sp.)
E: mouse (aka mus <genus>)
F: None of the above. | C |
<Instruct>: Given the context 'INTRODUCTION Ribonuclease A (RNase A, bovine pancreatic ribonuclease) is the prototype of an enlarging family of proteins defined by distinctive elements of conserved primary structure and enzymatic activity (1,2).', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: bos bubalis bubalis (aka bubalus bubalis bubalis)
B: dairy cow (aka bos taurus)
C: bos sp.
D: boveria
E: bos (cattle) (aka bos)
F: None of the above. | B |
<Instruct>: Given the context 'Pancreatic ribonucleases (RNases 1) have been isolated from an extensive array of mammalian species (3,4), and mRNA encoding human pancreatic ribonuclease has been detected in
numerous somatic tissues in addition to pancreas (5).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: homo sapiens (human) (aka homo sapiens)
B: kingdom
C: genus
D: biota (aka cellular organisms)
E: eutherian mammals (aka eutheria)
F: None of the above. | A |
<Instruct>: Given the context 'RNases 2 and 3, eosinophil-derived neurotoxin (EDN) and eosinophil cationic protein (ECP), respectively, have been characterized primarily with respect to eosinophil function (6,7), although expression of EDN [also known as RNase Us (8) or human liver ribonuclease (9)] is also widespread (5).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: birds (aka aves)
B: animals (aka metazoa)
C: human (aka homo sapiens)
D: primate (aka primates)
E: kingdom
F: None of the above. | C |
<Instruct>: Given the context 'Recently, Larson and colleagues (15) described cDNAs encoding two highly homologous murine ribonucleases, the murine eosinophil-associated ribonucleases (mEAR) 1 and 2, which were cloned and identified via tryptic peptides isolated from murine eosinophil proteins.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus cricetus (aka cricetus cricetus)
C: mice (aka mus <genus>) (aka mus <genus>)
D: mus sp. (mice (aka mus sp.))
E: peromyscus
F: None of the above. | A |
<Instruct>: Given the context 'Recently, Larson and colleagues (15) described cDNAs encoding two highly homologous murine ribonucleases, the murine eosinophil-associated ribonucleases (mEAR) 1 and 2, which were cloned and identified via tryptic peptides isolated from murine eosinophil proteins.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mice (aka mus sp.) (aka mus sp.)
B: mus (aka mus <genus>) (aka mus <genus>)
C: eastern european house mouse (aka mus musculus musculus)
D: mus <subgenus> (mus (aka mus <subgenus>))
E: western european house mouse (aka mus musculus domesticus)
F: None of the above. | F |
<Instruct>: Given the context 'Recently, Larson and colleagues (15) described cDNAs encoding two highly homologous murine ribonucleases, the murine eosinophil-associated ribonucleases (mEAR) 1 and 2, which were cloned and identified via tryptic peptides isolated from murine eosinophil proteins.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mouse (aka mus musculus)
B: mus cricetus (aka cricetus cricetus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: mus sp. (mice (aka mus sp.))
E: peromyscus
F: None of the above. | A |
<Instruct>: Given the context 'Recently, Larson and colleagues (15) described cDNAs encoding two highly homologous murine ribonucleases, the murine eosinophil-associated ribonucleases (mEAR) 1 and 2, which were cloned and identified via tryptic peptides isolated from murine eosinophil proteins.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mouse (aka mus musculus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mice (aka mus sp.) (aka mus sp.)
D: mus norvegicus (aka rattus norvegicus)
E: peromyscus
F: None of the above. | A |
<Instruct>: Given the context 'Although Southern analysis demonstrated that multiple copies of sequence homologous to mEAR-1 and mEAR-2 were present in murine genomic DNA, the precise nature of these copies--as pseudogenes, polymorphisms, or distinct functional genes--was unclear.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: mus norvegicus (aka rattus norvegicus)
C: mus sp. (mice (aka mus sp.))
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: mus (aka mus <genus>) (aka mus <genus>)
F: None of the above. | A |
<Instruct>: Given the context 'Together with mEAR-1 and mEAR-2, these six ribonuclease genes form an `mR cluster,' whose members are more closely related to one another than they are to other murine ribonucleases, yet whose position with respect to the defined RNase A lineages remains unclear.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: mouse (aka mus <genus>)
E: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
F: None of the above. | A |
<Instruct>: Given the context 'MATERIALS AND METHODS Isolation of genomic fragments encoding murine ribonucleases by polymerase chain reaction (PCR) Genomic DNA was isolated from cells of the murine 3T3 fibroblast cell line.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: house mouse (aka mus musculus)
C: mus <genus> (mice (aka mus <genus>))
D: western european house mouse (aka mus musculus domesticus)
E: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
F: None of the above. | B |
<Instruct>: Given the context 'MATERIALS AND METHODS Isolation of genomic fragments encoding murine ribonucleases by polymerase chain reaction (PCR) Genomic DNA was isolated from cells of the murine 3T3 fibroblast cell line.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus norvegicus (aka rattus norvegicus)
B: mus domesticus (aka mus musculus domesticus)
C: peromyscus
D: mus <subgenus> (mus (aka mus <subgenus>))
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Email: hr2k@nih.gov Present addresses: +Duke University School of Medicine, Durham, NC 27701, USA and �Department of Pediatrics, State University of New York-Health Sciences Center at Syracuse, Syracuse, NY 13210, USA
4236 Nucleic Acids Research, 1997, Vol. 25, No. 21
Figure 1. (A) Alignment of amino acid sequences encoded by six related murine ribonuclease genes.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus (aka mus <subgenus>) (aka mus <subgenus>)
B: mus cricetus (aka cricetus cricetus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: house mouse (aka mus musculus)
E: mouse (aka mus <genus>)
F: None of the above. | D |
<Instruct>: Given the context 'GenBank accession numbers: mEAR (murine eosinophil-associated ribonuclease)-1, U72032; mEAR-2, U72031; mR (murine ribonuclease)-3, AF017258; mR-4, AF017259; mR-5, AF017260; mR-6P (pseudogene), AF017261.
', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus norvegicus (aka rattus norvegicus)
B: eastern european house mouse (aka mus musculus musculus)
C: mus cricetus (aka cricetus cricetus)
D: western european house mouse (aka mus musculus domesticus)
E: mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'GenBank accession numbers: mEAR (murine eosinophil-associated ribonuclease)-1, U72032; mEAR-2, U72031; mR (murine ribonuclease)-3, AF017258; mR-4, AF017259; mR-5, AF017260; mR-6P (pseudogene), AF017261.
', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
B: mouse (aka mus musculus)
C: mus cricetus (aka cricetus cricetus)
D: peromyscus
E: mus (aka mus <genus>) (aka mus <genus>)
F: None of the above. | B |
<Instruct>: Given the context 'Northern analysis The murine multi-tissue Northern blot was purchased from Clontech, and pre-hybridized and hybridized as per manufacturer's instructions with radiolabelled oligonucleotide probes.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus <genus> (mice (aka mus <genus>))
B: mus <subgenus> (mus (aka mus <subgenus>))
C: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
D: mus musculus (house mouse) (aka mus musculus)
E: eastern european house mouse (aka mus musculus musculus)
F: None of the above. | D |
<Instruct>: Given the context 'Northern analysis The murine multi-tissue Northern blot was purchased from Clontech, and pre-hybridized and hybridized as per manufacturer's instructions with radiolabelled oligonucleotide probes.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mouse (aka mus <genus>)
B: eastern european house mouse (aka mus musculus musculus)
C: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
D: peromyscus
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | F |
<Instruct>: Given the context '4237 Nucleic Acids Research, 1997, Vol. 25, No. Nucleic Acids Research, 1994, Vol. 22, No. 121 4237
Figure 2. (A) Dendrogram depicting relationships among the eight characterized murine ribonucleases as determined by a modified UPGMA method (17).', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus norvegicus (aka rattus norvegicus)
B: eastern european house mouse (aka mus musculus musculus)
C: mus musculus (house mouse) (aka mus musculus)
D: mus cricetus (aka cricetus cricetus)
E: mus domesticus (aka mus musculus domesticus)
F: None of the above. | C |
<Instruct>: Given the context 'Abbreviations are as in Figure 1A, also mPR (murine pancreatic ribonuclease, sw:rnp_mouse), mANG (murine angiogenin, U72672), hEDN (human eosinophil-derived neurotoxin, M24157), hECP (human eosinophil cationic protein, X15161), hRK6 (human ribonuclease k6, U64998), pRK6 (porcine kidney ribonuclease (24), and bRK6 (bovine kidney ribonuclease, sw:rnkd_bovin).', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mouse (aka mus musculus)
B: mus <subgenus> (mus (aka mus <subgenus>))
C: eastern european house mouse (aka mus musculus musculus)
D: western european house mouse (aka mus musculus domesticus)
E: mus norvegicus (aka rattus norvegicus)
F: None of the above. | A |
<Instruct>: Given the context 'Abbreviations are as in Figure 1A, also mPR (murine pancreatic ribonuclease, sw:rnp_mouse), mANG (murine angiogenin, U72672), hEDN (human eosinophil-derived neurotoxin, M24157), hECP (human eosinophil cationic protein, X15161), hRK6 (human ribonuclease k6, U64998), pRK6 (porcine kidney ribonuclease (24), and bRK6 (bovine kidney ribonuclease, sw:rnkd_bovin).', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: mice (aka mus sp.) (aka mus sp.)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: house mouse (aka mus musculus)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | D |
<Instruct>: Given the context 'Abbreviations are as in Figure 1A, also mPR (murine pancreatic ribonuclease, sw:rnp_mouse), mANG (murine angiogenin, U72672), hEDN (human eosinophil-derived neurotoxin, M24157), hECP (human eosinophil cationic protein, X15161), hRK6 (human ribonuclease k6, U64998), pRK6 (porcine kidney ribonuclease (24), and bRK6 (bovine kidney ribonuclease, sw:rnkd_bovin).', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: western european house mouse (aka mus musculus domesticus)
C: peromyscus
D: house mouse (aka mus musculus)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | D |
<Instruct>: Given the context 'Abbreviations are as in Figure 1A, also mPR (murine pancreatic ribonuclease, sw:rnp_mouse), mANG (murine angiogenin, U72672), hEDN (human eosinophil-derived neurotoxin, M24157), hECP (human eosinophil cationic protein, X15161), hRK6 (human ribonuclease k6, U64998), pRK6 (porcine kidney ribonuclease (24), and bRK6 (bovine kidney ribonuclease, sw:rnkd_bovin).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: animals (aka metazoa)
B: macrobiotus sapiens
C: human (aka homo sapiens)
D: suborder
E: kingdom
F: None of the above. | C |
<Instruct>: Given the context 'Abbreviations are as in Figure 1A, also mPR (murine pancreatic ribonuclease, sw:rnp_mouse), mANG (murine angiogenin, U72672), hEDN (human eosinophil-derived neurotoxin, M24157), hECP (human eosinophil cationic protein, X15161), hRK6 (human ribonuclease k6, U64998), pRK6 (porcine kidney ribonuclease (24), and bRK6 (bovine kidney ribonuclease, sw:rnkd_bovin).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: this
B: macrobiotus sapiens
C: placental mammals (aka eutheria)
D: homo sapiens (human) (aka homo sapiens)
E: suborder
F: None of the above. | D |
<Instruct>: Given the context 'Abbreviations are as in Figure 1A, also mPR (murine pancreatic ribonuclease, sw:rnp_mouse), mANG (murine angiogenin, U72672), hEDN (human eosinophil-derived neurotoxin, M24157), hECP (human eosinophil cationic protein, X15161), hRK6 (human ribonuclease k6, U64998), pRK6 (porcine kidney ribonuclease (24), and bRK6 (bovine kidney ribonuclease, sw:rnkd_bovin).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: suborder
B: animals (aka metazoa)
C: homo sapiens (human) (aka homo sapiens)
D: primate (aka primates)
E: macrobiotus sapiens
F: None of the above. | C |
<Instruct>: Given the context 'Abbreviations are as in Figure 1A, also mPR (murine pancreatic ribonuclease, sw:rnp_mouse), mANG (murine angiogenin, U72672), hEDN (human eosinophil-derived neurotoxin, M24157), hECP (human eosinophil cationic protein, X15161), hRK6 (human ribonuclease k6, U64998), pRK6 (porcine kidney ribonuclease (24), and bRK6 (bovine kidney ribonuclease, sw:rnkd_bovin).', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: bos bubalis (aka bubalus bubalis)
B: bovinae
C: dairy cow (aka bos taurus)
D: cattle (aka bos)
E: bos sp.
F: None of the above. | C |
<Instruct>: Given the context 'Amino acid sequence comparisons of murine and human ribonucleases
Sequence analysis All DNA sequence analysis and comparisons were performed with the assistance of the Wisconsin Genetics Computer Group and Sequencher (Gene Codes Corporation) programs available at the National Institutes of Health.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus <genus> (mice (aka mus <genus>))
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Amino acid sequence comparisons of murine and human ribonucleases
Sequence analysis All DNA sequence analysis and comparisons were performed with the assistance of the Wisconsin Genetics Computer Group and Sequencher (Gene Codes Corporation) programs available at the National Institutes of Health.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: human (aka homo sapiens)
B: macrobiotus sapiens
C: birds (aka aves)
D: suborder
E: placental mammals (aka eutheria)
F: None of the above. | A |
<Instruct>: Given the context 'Amino acid sequence comparisons of murine and human ribonucleases
Sequence analysis All DNA sequence analysis and comparisons were performed with the assistance of the Wisconsin Genetics Computer Group and Sequencher (Gene Codes Corporation) programs available at the National Institutes of Health.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: suborder
B: this
C: biota (aka cellular organisms)
D: animals (aka metazoa)
E: genus
F: None of the above. | F |
<Instruct>: Given the context 'RESULTS Isolation of genomic fragments encoding novel murine ribonucleases The alignment in Figure 1A displays the amino acid sequences encoded by the six related ribonuclease genes.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: peromyscus
B: mus musculus (house mouse) (aka mus musculus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus norvegicus (aka rattus norvegicus)
F: None of the above. | B |
<Instruct>: Given the context 'Murine eosinophil-associated ribonucleases-1 and -2 (mEAR-1 and mEAR-2) are the predicted amino acid sequences from two genes described previously by Larson and colleagues (15); murine ribonucleases 3, 4, 5 and 6-pseudogene (mR-3, mR-4, mR-5 and mR-6P), are the predicted amino acid sequences encoded by novel DNA
hEDN mEAR-1 mEAR-2 mR-3 mR-4 mR-5 mANG mPR 56 56 54 60 60 43 53
hECP 59 59 57 59 58 49 52
hRK6 58 59 59 53 56 49 59
hPR 47 48 49 48 57 55 79
hR4 50 53 51 52 54 57 66
hANG 49 48 51 47 47 80 60
Values are expressed as percent similarity between pairs of amino acid sequences as determined by the BESTFIT algorithm of the Wisconsin Genetics Computer Group program on-line at the National Institutes of Health.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mouse (aka mus musculus)
B: mus cricetus (aka cricetus cricetus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: eastern european house mouse (aka mus musculus musculus)
E: mus domesticus (aka mus musculus domesticus)
F: None of the above. | A |
<Instruct>: Given the context 'Murine eosinophil-associated ribonucleases-1 and -2 (mEAR-1 and mEAR-2) are the predicted amino acid sequences from two genes described previously by Larson and colleagues (15); murine ribonucleases 3, 4, 5 and 6-pseudogene (mR-3, mR-4, mR-5 and mR-6P), are the predicted amino acid sequences encoded by novel DNA
hEDN mEAR-1 mEAR-2 mR-3 mR-4 mR-5 mANG mPR 56 56 54 60 60 43 53
hECP 59 59 57 59 58 49 52
hRK6 58 59 59 53 56 49 59
hPR 47 48 49 48 57 55 79
hR4 50 53 51 52 54 57 66
hANG 49 48 51 47 47 80 60
Values are expressed as percent similarity between pairs of amino acid sequences as determined by the BESTFIT algorithm of the Wisconsin Genetics Computer Group program on-line at the National Institutes of Health.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: eastern european house mouse (aka mus musculus musculus)
B: mus domesticus (aka mus musculus domesticus)
C: peromyscus
D: mouse (aka mus <genus>)
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Abbreviations are as defined in Figures 1 and 2, and also include hR4 (human ribonuclease 4, sw:rnl4_human), hANG (human angiogenin, M11567), and hPR (human pancreatic ribonuclease, X62946).
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: kingdom
B: biota (aka cellular organisms)
C: animals (aka metazoa)
D: homo sapiens (human) (aka homo sapiens)
E: mammals (aka mammalia)
F: None of the above. | D |
<Instruct>: Given the context 'Abbreviations are as defined in Figures 1 and 2, and also include hR4 (human ribonuclease 4, sw:rnl4_human), hANG (human angiogenin, M11567), and hPR (human pancreatic ribonuclease, X62946).
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: homo (humans) (aka homo)
B: human (aka homo sapiens)
C: mammals (aka mammalia)
D: this
E: primate (aka primates)
F: None of the above. | B |
<Instruct>: Given the context 'Abbreviations are as defined in Figures 1 and 2, and also include hR4 (human ribonuclease 4, sw:rnl4_human), hANG (human angiogenin, M11567), and hPR (human pancreatic ribonuclease, X62946).
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: primate (aka primates)
B: cellular organisms (biota) (aka cellular organisms)
C: placental mammals (aka eutheria)
D: human (aka homo sapiens)
E: this
F: None of the above. | D |
<Instruct>: Given the context 'Abbreviations are as defined in Figures 1 and 2, and also include hR4 (human ribonuclease 4, sw:rnl4_human), hANG (human angiogenin, M11567), and hPR (human pancreatic ribonuclease, X62946).
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: animals (aka metazoa)
B: this
C: homo sapiens (human) (aka homo sapiens)
D: kingdom
E: species
F: None of the above. | C |
<Instruct>: Given the context '4238 Nucleic Acids Research, 1997, Vol. 25, No. 21 fragments amplified from murine genomic DNA.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus domesticus (aka mus musculus domesticus)
B: mus cricetus (aka cricetus cricetus)
C: mice (aka mus sp.) (aka mus sp.)
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: house mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Relationships among the murine ribonucleases A dendrogram depicting the relationships among several of the murine and human ribonucleases is shown in Figure 2A.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: peromyscus
C: mus <subgenus> (mus (aka mus <subgenus>))
D: mice (aka mus <genus>) (aka mus <genus>)
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Relationships among the murine ribonucleases A dendrogram depicting the relationships among several of the murine and human ribonucleases is shown in Figure 2A.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: mice (aka mus sp.) (aka mus sp.)
C: mus norvegicus (aka rattus norvegicus)
D: eastern european house mouse (aka mus musculus musculus)
E: peromyscus
F: None of the above. | A |
<Instruct>: Given the context 'Relationships among the murine ribonucleases A dendrogram depicting the relationships among several of the murine and human ribonucleases is shown in Figure 2A.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: mus (aka mus <genus>) (aka mus <genus>)
C: mus sp. (mice (aka mus sp.))
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: western european house mouse (aka mus musculus domesticus)
F: None of the above. | F |
<Instruct>: Given the context 'Relationships among the murine ribonucleases A dendrogram depicting the relationships among several of the murine and human ribonucleases is shown in Figure 2A.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: this
B: homo sapiens (human) (aka homo sapiens)
C: suborder
D: mammals (aka mammalia)
E: homo (humans) (aka homo)
F: None of the above. | B |
<Instruct>: Given the context 'These six sequences are more closely related to one another than they are to either murine pancreatic ribonuclease (mPR) or to murine angiogenin (mANG) or to any of the three human ribonucleases shown (hEDN, hECP or hRK6).', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus norvegicus (aka rattus norvegicus)
B: mus cricetus (aka cricetus cricetus)
C: peromyscus
D: mice (aka mus <genus>) (aka mus <genus>)
E: mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'These six sequences are more closely related to one another than they are to either murine pancreatic ribonuclease (mPR) or to murine angiogenin (mANG) or to any of the three human ribonucleases shown (hEDN, hECP or hRK6).', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: mice (aka mus sp.) (aka mus sp.)
C: house mouse (aka mus musculus)
D: peromyscus
E: eastern european house mouse (aka mus musculus musculus)
F: None of the above. | C |
<Instruct>: Given the context 'These six sequences are more closely related to one another than they are to either murine pancreatic ribonuclease (mPR) or to murine angiogenin (mANG) or to any of the three human ribonucleases shown (hEDN, hECP or hRK6).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: homo sapiens (human) (aka homo sapiens)
B: genus
C: species
D: probles
E: birds (aka aves)
F: None of the above. | A |
<Instruct>: Given the context 'Northern analysis Tissue-specific expression of mRNA encoding these murine ribonucleases is shown in Figure 3.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus sp. (mice (aka mus sp.))
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus musculus (house mouse) (aka mus musculus)
D: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
E: eastern european house mouse (aka mus musculus musculus)
F: None of the above. | C |
<Instruct>: Given the context 'A prominent mRNA of 1.8 kb was also detected in mRNA isolated from murine testicular tissue; fainter hybridizing mRNAs of varying size were detected in lung and skeletal muscle.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mice (aka mus sp.) (aka mus sp.)
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: mus norvegicus (aka rattus norvegicus)
D: mus cricetus (aka cricetus cricetus)
E: mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'The size variation may represent differential splicing of the mR-5-encoding mRNA, or may represent mRNAs encoding one or more as yet undiscovered murine ribonucleases that are more closely related to mR-5 than those whose sequences are reported here.
', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus musculus (house mouse) (aka mus musculus)
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: mus domesticus (aka mus musculus domesticus)
F: None of the above. | C |
<Instruct>: Given the context 'Figure 3. (A) Murine RNA probed with a 32 bp oligonucleotide complementary to mEAR-1, mEAR-2 and mR-3 coding sequences.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: peromyscus
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
D: eastern european house mouse (aka mus musculus musculus)
E: house mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context '(C) Same as in (A), probed with a 48 bp oligonucleotide complementary to human actin (16), demonstrating relative loading of each lane.
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: this
B: kingdom
C: animals (aka metazoa)
D: macrobiotus sapiens
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | E |
<Instruct>: Given the context 'Relationship to human ribonucleases The data in Table 1 denote the amino acid sequence similarity between pairs of murine and human ribonucleases of the RNase A superfamily.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: eutherian mammals (aka eutheria)
B: human (aka homo sapiens)
C: macrobiotus sapiens
D: cellular organisms (biota) (aka cellular organisms)
E: homo (humans) (aka homo)
F: None of the above. | B |
<Instruct>: Given the context 'Relationship to human ribonucleases The data in Table 1 denote the amino acid sequence similarity between pairs of murine and human ribonucleases of the RNase A superfamily.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: cellular organisms (biota) (aka cellular organisms)
B: mammals (aka mammalia)
C: birds (aka aves)
D: this
E: species
F: None of the above. | F |
<Instruct>: Given the context 'Relationship to human ribonucleases The data in Table 1 denote the amino acid sequence similarity between pairs of murine and human ribonucleases of the RNase A superfamily.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: western european house mouse (aka mus musculus domesticus)
B: mouse (aka mus musculus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: peromyscus
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | B |
<Instruct>: Given the context 'Relationship to human ribonucleases The data in Table 1 denote the amino acid sequence similarity between pairs of murine and human ribonucleases of the RNase A superfamily.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: kingdom
B: this
C: human (aka homo sapiens)
D: homo (humans) (aka homo)
E: placental mammals (aka eutheria)
F: None of the above. | C |
<Instruct>: Given the context 'Although the sequences of the mEAR-1/mEAR-2/mR-3 subgroup are slightly more similar to ECP and RNase k6, and mR-4 and mR-5, to EDN and ECP, the orthologous relationships of these murine ribonucleases cannot be discerned from these data.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: peromyscus
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: eastern european house mouse (aka mus musculus musculus)
E: western european house mouse (aka mus musculus domesticus)
F: None of the above. | A |
<Instruct>: Given the context 'This stands in direct contrast to mPR and mANG, whose human orthologs can be clearly distinguished on the basis of their amino acid sequence homologies.
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: kingdom
B: cellular organisms (biota) (aka cellular organisms)
C: placental mammals (aka eutheria)
D: homo sapiens (human) (aka homo sapiens)
E: probles
F: None of the above. | D |
<Instruct>: Given the context 'DISCUSSION In this work, we have identified four novel murine ribonuclease genes that, together with mEAR-1 and mEAR-2 defined by Larson and colleagues (15), form an unusual cluster within the RNase A gene superfamily.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus norvegicus (aka rattus norvegicus)
D: peromyscus
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'The six genes within this cluster have varying amino acid sequence homologies to one another, but are clearly more closely related to one another than to either murine pancreatic ribonuclease (mPR) or angiogenin (mANG), or to any of the human ribonucleases of the RNase A family.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: mouse (aka mus musculus)
C: mus domesticus (aka mus musculus domesticus)
D: mus norvegicus (aka rattus norvegicus)
E: mus <subgenus> (mus (aka mus <subgenus>))
F: None of the above. | B |
<Instruct>: Given the context 'The six genes within this cluster have varying amino acid sequence homologies to one another, but are clearly more closely related to one another than to either murine pancreatic ribonuclease (mPR) or angiogenin (mANG), or to any of the human ribonucleases of the RNase A family.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: humans (aka homo)
B: animals (aka metazoa)
C: human (aka homo sapiens)
D: this
E: avian (aka aves)
F: None of the above. | C |
<Instruct>: Given the context 'These results suggest that the `mR cluster' emerged via multiple duplications of a gene that had already diverged from those encoding the other murine ribonucleases.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus (aka mus <genus>) (aka mus <genus>)
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: eastern european house mouse (aka mus musculus musculus)
F: None of the above. | A |
<Instruct>: Given the context 'Although this type of expansion is unusual in this gene family, it is actually not unique; similar expansion has occurred in bovine species, with gene duplication resulting in the three closely-related bovine pancreatic, bovine brain (19,20) and bovine seminal (21) ribonucleases.', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: cattle (aka bos)
B: bos bubalis (aka bubalus bubalis)
C: bos taurus x bos indicus (aka bos indicus x bos taurus)
D: ox (aka bos taurus) (aka bos taurus)
E: bos sp.
F: None of the above. | D |
<Instruct>: Given the context 'Although this type of expansion is unusual in this gene family, it is actually not unique; similar expansion has occurred in bovine species, with gene duplication resulting in the three closely-related bovine pancreatic, bovine brain (19,20) and bovine seminal (21) ribonucleases.', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: bos bubalis (aka bubalus bubalis)
B: bos taurus (bos primigenius taurus) (aka bos taurus)
C: bovidae
D: bos bubalis bubalis (aka bubalus bubalis bubalis)
E: bovinae
F: None of the above. | B |
<Instruct>: Given the context 'Although this type of expansion is unusual in this gene family, it is actually not unique; similar expansion has occurred in bovine species, with gene duplication resulting in the three closely-related bovine pancreatic, bovine brain (19,20) and bovine seminal (21) ribonucleases.', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: bos bubalis bubalis (aka bubalus bubalis bubalis)
B: bos sp.
C: bos indicus (bos primigenius indicus) (aka bos indicus)
D: boveria
E: cattle (aka bos)
F: None of the above. | F |
<Instruct>: Given the context 'Although this type of expansion is unusual in this gene family, it is actually not unique; similar expansion has occurred in bovine species, with gene duplication resulting in the three closely-related bovine pancreatic, bovine brain (19,20) and bovine seminal (21) ribonucleases.', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: bos sp.
B: bos taurus x bos indicus (aka bos indicus x bos taurus)
C: bos (cattle) (aka bos)
D: bos bubalis (aka bubalus bubalis)
E: bos taurus (bos primigenius taurus) (aka bos taurus)
F: None of the above. | E |
<Instruct>: Given the context 'Although this type of expansion is unusual in this gene family, it is actually not unique; similar expansion has occurred in bovine species, with gene duplication resulting in the three closely-related bovine pancreatic, bovine brain (19,20) and bovine seminal (21) ribonucleases.', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: bos taurus indicus (aka bos indicus)
B: bos taurus x bos indicus (aka bos indicus x bos taurus)
C: boveria
D: domestic cattle (aka bos taurus)
E: bovidae
F: None of the above. | D |
<Instruct>: Given the context 'One interesting feature of the mR cluster is that its relationship to any of to the six known human RNase A-type genes cannot be
4239 Nucleic Acids Research, 1997, Vol. 25, No.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: genus
B: homo sapiens (human) (aka homo sapiens)
C: kingdom
D: birds (aka aves)
E: macrobiotus sapiens
F: None of the above. | B |
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