instruction stringlengths 209 946 | input stringlengths 96 1.45k | response stringlengths 3 12 |
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<Instruct>: Given the context 'Irrespective of their effects on ongoing host protein synthesis, productive replication of the representative alphaherpesvirus herpes simplex virus type 1, the representative gammaherpesvirus Kaposi's sarcoma herpesvirus, and the representative betaherpesvirus human cytomegalovirus [HCMV] stimulates the assembly of the multisubunit, cap-binding translation factor eIF4F. However, only HCMV replication is associated with an increased abundance of eIF4F core components (eIF4E, eIF4G, eIF4A) and the eIF4F-associated factor poly(A) binding protein (PABP).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [herpes simplex virus type 1; kaposi's sarcoma herpesvirus; human cytomegalovirus; hcmv]
<Options>: A: hsv1 (aka human alphaherpesvirus 1) (aka human alphaherpesvirus 1)
B: kaposi's sarcoma-associated herpesvirus - human herpesvirus 8 (aka human gammaherpesvirus 8)
C: murine cytomegalovirus (aka murid betaherpesvirus 1)
D: unidentified cytomegalovirus
E: phocid herpesvirus 1 (aka phocid alphaherpesvirus 1)
F: hhv-3 (aka human alphaherpesvirus 3)
G: human cytomegalovirus (aka human betaherpesvirus 5)
H: human herpesvirus 8 (aka human gammaherpesvirus 8)
I: human herpesvirus 5 strain ad169 (human cytomegalovirus (strain ad169)) (aka human herpesvirus 5 strain ad169)
J: human alphaherpesvirus 1 strain kos (herpes simplex virus (type 1 / strain kos)) (aka human alphaherpesvirus 1 strain kos)
K: herpes simplexvirus
L: herpes virus b (aka macacine alphaherpesvirus 1)
M: rat cytomegalovirus (aka murid betaherpesvirus 2)
N: herpes simplex virus (type 1 / strain f) (aka human alphaherpesvirus 1 strain f)
O: human herpesvirus 1 (aka human alphaherpesvirus 1)
P: hhv-7 (aka human betaherpesvirus 7)
Q: japanese cytomegalovirus
R: herpes simplex virus ii (aka human alphaherpesvirus 2)
S: None of the above. | [A; B; G; G] |
<Instruct>: Given the context 'Irrespective of their effects on ongoing host protein synthesis, productive replication of the representative alphaherpesvirus herpes simplex virus type 1, the representative gammaherpesvirus Kaposi's sarcoma herpesvirus, and the representative betaherpesvirus human cytomegalovirus [HCMV] stimulates the assembly of the multisubunit, cap-binding translation factor eIF4F. However, only HCMV replication is associated with an increased abundance of eIF4F core components (eIF4E, eIF4G, eIF4A) and the eIF4F-associated factor poly(A) binding protein (PABP).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [herpes simplex virus type 1; kaposi's sarcoma herpesvirus; human cytomegalovirus; hcmv]
<Options>: A: human herpesvirus 5 (aka human betaherpesvirus 5)
B: simian herpes b virus (aka macacine alphaherpesvirus 1)
C: phocid herpesvirus-1 (aka phocid alphaherpesvirus 1)
D: herpes simplex virus (type 1 / strain f) (aka human alphaherpesvirus 1 strain f)
E: japanese cytomegalovirus
F: unidentified cytomegalovirus
G: human herpesvirus type 1 (aka human alphaherpesvirus 1)
H: human alphaherpesvirus 2 (herpes simplex virus type 2 (hsv-2)) (aka human alphaherpesvirus 2)
I: hhv-3 (aka human alphaherpesvirus 3)
J: kaposi's sarcoma-associated herpesvirus (aka human gammaherpesvirus 8)
K: herpes simplexvirus
L: cytomegalovirus
M: herpes simplex virus (type 1 / strain kos) (aka human alphaherpesvirus 1 strain kos)
N: human cytomegalovirus (strain pt) (aka human herpesvirus 5 strain pt)
O: human herpesvirus 7 (aka human betaherpesvirus 7)
P: rhesus cytomegalovirus (aka macacine betaherpesvirus 3)
Q: human herpesvirus 2 (aka human alphaherpesvirus 2)
R: herpes simplex virus 1 (aka human alphaherpesvirus 1)
S: None of the above. | [R; J; A; A] |
<Instruct>: Given the context 'Irrespective of their effects on ongoing host protein synthesis, productive replication of the representative alphaherpesvirus herpes simplex virus type 1, the representative gammaherpesvirus Kaposi's sarcoma herpesvirus, and the representative betaherpesvirus human cytomegalovirus [HCMV] stimulates the assembly of the multisubunit, cap-binding translation factor eIF4F. However, only HCMV replication is associated with an increased abundance of eIF4F core components (eIF4E, eIF4G, eIF4A) and the eIF4F-associated factor poly(A) binding protein (PABP).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [herpes simplex virus type 1; kaposi's sarcoma herpesvirus; human cytomegalovirus; hcmv]
<Options>: A: human cytomegalovirus (aka human betaherpesvirus 5)
B: rat cytomegalovirus (aka murid betaherpesvirus 2)
C: hhv-7 (aka human betaherpesvirus 7)
D: human herpesvirus type 7 (aka human betaherpesvirus 7)
E: herpes b virus (aka macacine alphaherpesvirus 1)
F: human alphaherpesvirus 1 strain f (herpes simplex virus (type 1 / strain f)) (aka human alphaherpesvirus 1 strain f)
G: kaptombes virus
H: human alphaherpesvirus 1 strain kos (herpes simplex virus (type 1 / strain kos)) (aka human alphaherpesvirus 1 strain kos)
I: cottontail herpesvirus (aka herpesvirus sylvilagus)
J: herpes simplexvirus
K: human herpesvirus 2 (aka human alphaherpesvirus 2)
L: human gammaherpesvirus 8 (kaposi's sarcoma-associated herpesvirus - human herpesvirus 8) (aka human gammaherpesvirus 8)
M: human herpesvirus 1 (aka human alphaherpesvirus 1)
N: rodent herpesvirus
O: herpes simplex virus 1 hsv-1 (aka human alphaherpesvirus 1)
P: herpes simplex virus ii (aka human alphaherpesvirus 2)
Q: human herpesvirus 8 (aka human gammaherpesvirus 8)
R: None of the above. | [O; L; A; A] |
<Instruct>: Given the context 'Irrespective of their effects on ongoing host protein synthesis, productive replication of the representative alphaherpesvirus herpes simplex virus type 1, the representative gammaherpesvirus Kaposi's sarcoma herpesvirus, and the representative betaherpesvirus human cytomegalovirus [HCMV] stimulates the assembly of the multisubunit, cap-binding translation factor eIF4F. However, only HCMV replication is associated with an increased abundance of eIF4F core components (eIF4E, eIF4G, eIF4A) and the eIF4F-associated factor poly(A) binding protein (PABP).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [herpes simplex virus type 1; kaposi's sarcoma herpesvirus; human cytomegalovirus; hcmv]
<Options>: A: unidentified cytomegalovirus
B: herpesvirus sylvilagus (rabbit gamma-herpesvirus) (aka herpesvirus sylvilagus)
C: human cytomegalovirus (strain 1042) (aka human herpesvirus 5 (strain 1042))
D: human alphaherpesvirus 1 strain kos (herpes simplex virus (type 1 / strain kos)) (aka human alphaherpesvirus 1 strain kos)
E: hhv-3 (aka human alphaherpesvirus 3)
F: human herpesvirus 2 (aka human alphaherpesvirus 2)
G: rat cytomegalovirus (aka murid betaherpesvirus 2)
H: herpesvirus tamarinus (aka saimiriine alphaherpesvirus 1)
I: herpes simplex virus type 1 hsv1 (aka human alphaherpesvirus 1)
J: japanese cytomegalovirus
K: human herpesvirus 5 strain ad169 (human cytomegalovirus (strain ad169)) (aka human herpesvirus 5 strain ad169)
L: kaposi's sarcoma-associated herpes-like virus (aka human gammaherpesvirus 8)
M: herpes simplex virus ii (aka human alphaherpesvirus 2)
N: herpesvirus m (aka saimiriine alphaherpesvirus 1)
O: human herpesvirus 5 (aka human betaherpesvirus 5)
P: hhv-7 (aka human betaherpesvirus 7)
Q: herpes simplex virus (type 1 / strain f) (aka human alphaherpesvirus 1 strain f)
R: human herpesvirus 6b (aka human betaherpesvirus 6b)
S: herpes simplexvirus
T: None of the above. | [I; L; O; O] |
<Instruct>: Given the context 'Irrespective of their effects on ongoing host protein synthesis, productive replication of the representative alphaherpesvirus herpes simplex virus type 1, the representative gammaherpesvirus Kaposi's sarcoma herpesvirus, and the representative betaherpesvirus human cytomegalovirus [HCMV] stimulates the assembly of the multisubunit, cap-binding translation factor eIF4F. However, only HCMV replication is associated with an increased abundance of eIF4F core components (eIF4E, eIF4G, eIF4A) and the eIF4F-associated factor poly(A) binding protein (PABP).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hcmv]
<Options>: A: human herpesvirus 6b (aka human betaherpesvirus 6b)
B: human herpesvirus 8 (aka human gammaherpesvirus 8)
C: human herpesvirus 5 (aka human betaherpesvirus 5)
D: murine cytomegalovirus (aka murid betaherpesvirus 1)
E: human betaherpesvirus 6a (human herpesvirus 6a) (aka human betaherpesvirus 6a)
F: None of the above. | [C] |
<Instruct>: Given the context 'Here, we demonstrate that the increase in translation factor concentration was readily detected in an asynchronous population of HCMV-infected primary human fibroblasts, abolished by prior UV inactivation of virus, and genetically dependent upon viral immediate-early genes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hcmv; human]
<Options>: A: unidentified cytomegalovirus
B: glossus humanus (cardium humanum) (aka glossus humanus)
C: human herpesvirus 7 (aka human betaherpesvirus 7)
D: human betaherpesvirus 6a (human herpesvirus 6a) (aka human betaherpesvirus 6a)
E: human betaherpesvirus 5 (human herpesvirus type 5) (aka human betaherpesvirus 5)
F: neandertal man (aka homo sapiens neanderthalensis)
G: homo sapiens (human) (aka homo sapiens)
H: carcharhinus humani
I: human herpesvirus type 1 (aka human alphaherpesvirus 1)
J: homo (humans) (aka homo)
K: None of the above. | [E; G] |
<Instruct>: Given the context 'Here, we demonstrate that the increase in translation factor concentration was readily detected in an asynchronous population of HCMV-infected primary human fibroblasts, abolished by prior UV inactivation of virus, and genetically dependent upon viral immediate-early genes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hcmv; human]
<Options>: A: homo (humans) (aka homo)
B: sphaeria humana (aka sordaria humana)
C: human louse (aka pediculus humanus)
D: carcharhinus humani
E: human herpesvirus 1 (aka human alphaherpesvirus 1)
F: unidentified cytomegalovirus
G: homo sapiens (human) (aka homo sapiens)
H: human herpesvirus type 5 (aka human betaherpesvirus 5)
I: herpes b virus (aka macacine alphaherpesvirus 1)
J: human herpesvirus 5 strain ad169 (human cytomegalovirus (strain ad169)) (aka human herpesvirus 5 strain ad169)
K: None of the above. | [H; G] |
<Instruct>: Given the context 'Strikingly, while increased mRNA steady-state levels accompanied the rise in eIF4E and eIF4G protein levels, the overall abundance of PABP mRNA, together with the half-life of the polypeptide it encodes, remained relatively unchanged by HCMV infection.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hcmv]
<Options>: A: human herpesvirus 5 strain ad169 (human cytomegalovirus (strain ad169)) (aka human herpesvirus 5 strain ad169)
B: rodent herpesvirus
C: human betaherpesvirus 6a (human herpesvirus 6a) (aka human betaherpesvirus 6a)
D: human betaherpesvirus 5 (human herpesvirus type 5) (aka human betaherpesvirus 5)
E: cytomegalovirus
F: None of the above. | [D] |
<Instruct>: Given the context 'Instead, HCMV-induced PABP accumulation resulted from new protein synthesis and was sensitive to the mTORC1-selective inhibitor rapamycin, which interferes with phosphorylation of the mTORC1 substrate p70 S6K and the translational repressor 4E-BP1.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hcmv]
<Options>: A: murine cytomegalovirus (aka murid betaherpesvirus 1)
B: human betaherpesvirus 5 (human herpesvirus type 5) (aka human betaherpesvirus 5)
C: human herpesvirus 5 strain ad169 (human cytomegalovirus (strain ad169)) (aka human herpesvirus 5 strain ad169)
D: human herpesvirus 1 (aka human alphaherpesvirus 1)
E: human betaherpesvirus 6a (human herpesvirus 6a) (aka human betaherpesvirus 6a)
F: None of the above. | [B] |
<Instruct>: Given the context 'Finally, unlike the situation in alpha- or gammaherpesvirus-infected cells, where PABP is redistributed to nuclei, PABP accumulated in the cytoplasm of HCMV-infected cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hcmv]
<Options>: A: human herpesvirus 5 (aka human betaherpesvirus 5)
B: human herpesvirus 5 strain ad169 (human cytomegalovirus (strain ad169)) (aka human herpesvirus 5 strain ad169)
C: japanese cytomegalovirus
D: cytomegalovirus
E: human herpesvirus 7 (aka human betaherpesvirus 7)
F: None of the above. | [A] |
<Instruct>: Given the context 'Thus, cytoplasmic PABP accumulation is translationally controlled in HCMV-infected cells via a mechanism requiring mTORC1-mediated inhibition of the cellular 4E-BP1 translational repressor.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hcmv]
<Options>: A: murine cytomegalovirus (aka murid betaherpesvirus 1)
B: human herpesvirus 5 (aka human betaherpesvirus 5)
C: human herpesvirus 7 (aka human betaherpesvirus 7)
D: human herpesvirus 5 strain ad169 (human cytomegalovirus (strain ad169)) (aka human herpesvirus 5 strain ad169)
E: cytomegalovirus
F: None of the above. | [B] |
<Instruct>: Given the context 'Thus, cytoplasmic PABP accumulation is translationally controlled in HCMV-infected cells via a mechanism requiring mTORC1-mediated inhibition of the cellular 4E-BP1 translational repressor.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hcmv]
<Options>: A: human herpesvirus 5 strain ad169 (human cytomegalovirus (strain ad169)) (aka human herpesvirus 5 strain ad169)
B: murine cytomegalovirus (aka murid betaherpesvirus 1)
C: cytomegalovirus
D: human herpesvirus 7 (aka human betaherpesvirus 7)
E: None of the above. | [E] |
<Instruct>: Given the context 'A new model of Epstein-Barr virus infection reveals an important role for earlylytic viral protein expression in the development of lymphomas.
Epstein-Barr virus (EBV) infects cells in latent or lytic forms, but the roleof lytic infection in EBV-induced lymphomas is unclear.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [epstein-barr virus; ebv]
<Options>: A: epstein-barr virus ebv (aka human gammaherpesvirus 4)
B: bat herpesvirus
C: bovine herpesvirus-1 (aka bovine alphaherpesvirus 1)
D: blhv (aka bovine lymphotropic herpesvirus) (aka bovine lymphotropic herpesvirus)
E: bat gammaherpesvirus
F: bovine torovirus
G: bat betaherpesvirus
H: bovine herpesvirus 2 (aka bovine alphaherpesvirus 2)
I: rhesus epstein barr virus (aka macacine gammaherpesvirus 4)
J: None of the above. | [A; A] |
<Instruct>: Given the context 'A new model of Epstein-Barr virus infection reveals an important role for earlylytic viral protein expression in the development of lymphomas.
Epstein-Barr virus (EBV) infects cells in latent or lytic forms, but the roleof lytic infection in EBV-induced lymphomas is unclear.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [epstein-barr virus; ebv]
<Options>: A: epstein-barr virus type 1 ebv-1 (aka human herpesvirus 4 type 1)
B: ebv (aka human gammaherpesvirus 4) (aka human gammaherpesvirus 4)
C: epstein-barr virus-2 ebv-2 (aka human herpesvirus 4 type 2)
D: burke virus
E: bat gammaherpesvirus
F: bovine herpesvirus-1 (aka bovine alphaherpesvirus 1)
G: bovine herpesvirus 2 (aka bovine alphaherpesvirus 2)
H: gb virus
I: epstein-barr virus (strain raji) (aka human herpesvirus 4 strain raji)
J: None of the above. | [B; B] |
<Instruct>: Given the context 'Here, we have used anew humanized mouse model, in which both human fetal CD34(+) hematopoietic stemcells and thymus/liver tissue are transplanted, to compare EBV pathogenesis andlymphoma formation following infection with a lytic replication-defectiveBZLF1-deleted (Z-KO) virus or a lytically active BZLF1(+) control.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse; human; ebv]
<Options>: A: bat gammaherpesvirus
B: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
C: mouse (aka mus musculus)
D: mus terricolor (earth-colored mouse) (aka mus terricolor)
E: bovine torovirus
F: beult virus
G: cardium humanum (aka glossus humanus)
H: mus famulus (servant mouse) (aka mus famulus)
I: burke virus
J: western wild mouse (aka mus spretus)
K: homo sapiens (human) (aka homo sapiens)
L: sphaeria humana (aka sordaria humana)
M: human louse (aka pediculus humanus)
N: epstein barr virus (aka human gammaherpesvirus 4)
O: carcharhinus humani
P: None of the above. | [C; K; N] |
<Instruct>: Given the context 'Here, we have used anew humanized mouse model, in which both human fetal CD34(+) hematopoietic stemcells and thymus/liver tissue are transplanted, to compare EBV pathogenesis andlymphoma formation following infection with a lytic replication-defectiveBZLF1-deleted (Z-KO) virus or a lytically active BZLF1(+) control.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse; human; ebv]
<Options>: A: human (aka homo sapiens)
B: bohxovirus
C: japanese wild mouse (aka mus musculus molossinus)
D: pediculus humanus (human louse) (aka pediculus humanus)
E: mus musculus (house mouse) (aka mus musculus)
F: mus macedonicus (macedonian mouse) (aka mus macedonicus)
G: mice (aka mus <genus>) (aka mus <genus>)
H: glossus humanus (cardium humanum) (aka glossus humanus)
I: bovine torovirus
J: pediculus humanus corporis (pediculus humanus humanus) (aka pediculus humanus corporis)
K: bat herpesvirus
L: western wild mouse (aka mus spretus)
M: homo (humans) (aka homo)
N: epstein barr virus (aka human gammaherpesvirus 4)
O: bohwovirus
P: None of the above. | [E; A; N] |
<Instruct>: Given the context 'Here, we have used anew humanized mouse model, in which both human fetal CD34(+) hematopoietic stemcells and thymus/liver tissue are transplanted, to compare EBV pathogenesis andlymphoma formation following infection with a lytic replication-defectiveBZLF1-deleted (Z-KO) virus or a lytically active BZLF1(+) control.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse; human; ebv]
<Options>: A: homo (humans) (aka homo)
B: bat herpesvirus
C: japanese wild mouse (aka mus musculus molossinus)
D: mus musculus (house mouse) (aka mus musculus)
E: mus macedonicus (macedonian mouse) (aka mus macedonicus)
F: bovine torovirus
G: glossus humanus (cardium humanum) (aka glossus humanus)
H: bohwovirus
I: human (aka homo sapiens)
J: mice (aka mus <genus>) (aka mus <genus>)
K: pediculus humanus corporis (pediculus humanus humanus) (aka pediculus humanus corporis)
L: pediculus humanus (human louse) (aka pediculus humanus)
M: western wild mouse (aka mus spretus)
N: bohxovirus
O: None of the above. | [D; I; O] |
<Instruct>: Given the context 'Here, we have used anew humanized mouse model, in which both human fetal CD34(+) hematopoietic stemcells and thymus/liver tissue are transplanted, to compare EBV pathogenesis andlymphoma formation following infection with a lytic replication-defectiveBZLF1-deleted (Z-KO) virus or a lytically active BZLF1(+) control.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse; human; ebv]
<Options>: A: mus molossinus (aka mus musculus molossinus)
B: gymnopleurus humanus
C: human (aka homo sapiens)
D: mice (aka mus <genus>) (aka mus <genus>)
E: mus terricolor (earth-colored mouse) (aka mus terricolor)
F: gb virus
G: human louse (aka pediculus humanus)
H: epstein-barr virus type 1 (aka human herpesvirus 4 type 1)
I: bat herpesvirus
J: bohxovirus oralis
K: mus musculus (house mouse) (aka mus musculus)
L: hominidae (great apes) (aka hominidae)
M: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
N: epstein-barr virus ebv (aka human gammaherpesvirus 4)
O: neanderthal man (aka homo sapiens neanderthalensis)
P: None of the above. | [K; C; N] |
<Instruct>: Given the context 'Specific immune responses against EBV-infected B cellswere generated in mice infected with either the control virus or the Z-KOvirus.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ebv; mice]
<Options>: A: bohnovirus
B: bohwovirus
C: western wild mouse (aka mus spretus)
D: human herpesvirus 4 (epstein-barr virus) (aka human gammaherpesvirus 4)
E: southeastern asian house mouse (aka mus musculus castaneus)
F: house mouse (aka mus musculus)
G: mus <genus> (mice (aka mus <genus>))
H: mus californicus (aka peromyscus californicus)
I: gb virus
J: beult virus
K: None of the above. | [D; F] |
<Instruct>: Given the context 'Specific immune responses against EBV-infected B cellswere generated in mice infected with either the control virus or the Z-KOvirus.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ebv; mice]
<Options>: A: beult virus
B: mus <genus> (mice (aka mus <genus>))
C: ebv (aka human gammaherpesvirus 4) (aka human gammaherpesvirus 4)
D: epstein-barr virus type 1 (aka human herpesvirus 4 type 1)
E: western wild mouse (aka mus spretus)
F: southeastern asian house mouse (aka mus musculus castaneus)
G: mus musculus (house mouse) (aka mus musculus)
H: mice (aka mus sp.) (aka mus sp.)
I: bovine torovirus
J: bovine lymphotropic herpesvirus (blhv (aka bovine lymphotropic herpesvirus))
K: None of the above. | [C; G] |
<Instruct>: Given the context 'These results point to animportant role for lytic EBV infection in the development of B cell lymphomasin the context of an active host immune response.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ebv]
<Options>: A: bohnovirus
B: beult virus
C: human herpesvirus 4 (epstein-barr virus) (aka human gammaherpesvirus 4)
D: bat gammaherpesvirus
E: bohwovirus
F: None of the above. | [C] |
<Instruct>: Given the context 'Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice; severe acute respiratory syndrome coronavirus]
<Options>: A: sars-cov (aka severe acute respiratory syndrome coronavirus)
B: mouse (aka mus <genus>)
C: sars-2 (aka severe acute respiratory syndrome coronavirus 2)
D: mus molossinus (aka mus musculus molossinus)
E: western wild mouse (aka mus spretus)
F: mus famulus (servant mouse) (aka mus famulus)
G: bat sars coronavirus (aka sars bat coronavirus)
H: mus musculus (house mouse) (aka mus musculus)
I: swine acute diarrhea syndrome coronavirus
J: sars-related coronavirus (aka severe acute respiratory syndrome-related coronavirus)
K: None of the above. | [H; J] |
<Instruct>: Given the context 'Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice; severe acute respiratory syndrome coronavirus]
<Options>: A: mus famulus (servant mouse) (aka mus famulus)
B: sars-2 (aka severe acute respiratory syndrome coronavirus 2)
C: mus molossinus (aka mus musculus molossinus)
D: sars-related coronavirus (aka severe acute respiratory syndrome-related coronavirus)
E: western wild mouse (aka mus spretus)
F: bat sars coronavirus (aka sars bat coronavirus)
G: mouse (aka mus <genus>)
H: sars-cov (aka severe acute respiratory syndrome coronavirus)
I: swine acute diarrhea syndrome coronavirus
J: None of the above. | [J; D] |
<Instruct>: Given the context 'Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice; severe acute respiratory syndrome coronavirus]
<Options>: A: human coronavirus (strain sars) (aka severe acute respiratory syndrome-related coronavirus)
B: mice (aka mus sp.) (aka mus sp.)
C: sars bat coronavirus (bat sars coronavirus) (aka sars bat coronavirus)
D: mus musculus (house mouse) (aka mus musculus)
E: mus famulus (servant mouse) (aka mus famulus)
F: sars coronavirus as
G: swine acute diarrhea syndrome coronavirus
H: sars-2 (aka severe acute respiratory syndrome coronavirus 2)
I: southeastern asian house mouse (aka mus musculus castaneus)
J: mus californicus (aka peromyscus californicus)
K: None of the above. | [D; A] |
<Instruct>: Given the context 'Newly emerging viruses often circulate as a heterogeneous swarm in wild animal reservoirs prior to their emergence in humans, and their antigenic identities are often unknown until an outbreak situation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [humans]
<Options>: A: cardium humanum (aka glossus humanus)
B: gymnopleurus humanus
C: neandertal man (aka homo sapiens neanderthalensis)
D: macrobiotus sapiens
E: human (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'The newly emerging severe acute respiratory syndrome coronavirus (SARS-CoV) and reemerging influenza virus cause disproportionate disease in the aged, who are also notoriously difficult to successfully vaccinate, likely due to immunosenescence.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [severe acute respiratory syndrome coronavirus; sars-cov]
<Options>: A: recombinant sars coronavirus
B: sars bat coronavirus (bat sars coronavirus) (aka sars bat coronavirus)
C: sars-related bat coronavirus (aka bat sars-like coronavirus)
D: sars-2 (aka severe acute respiratory syndrome coronavirus 2)
E: sars-like coronavirus (aka severe acute respiratory syndrome-related coronavirus)
F: swine acute diarrhea syndrome coronavirus
G: sars coronavirus as
H: bat sars coronavirus (aka sars bat coronavirus)
I: None of the above. | [E; E] |
<Instruct>: Given the context 'The newly emerging severe acute respiratory syndrome coronavirus (SARS-CoV) and reemerging influenza virus cause disproportionate disease in the aged, who are also notoriously difficult to successfully vaccinate, likely due to immunosenescence.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [severe acute respiratory syndrome coronavirus; sars-cov]
<Options>: A: sars-cov (urbani strain) (aka sars coronavirus urbani)
B: sars bat coronavirus (bat sars coronavirus) (aka sars bat coronavirus)
C: sars-like coronavirus (aka severe acute respiratory syndrome-related coronavirus)
D: sars coronavirus (aka severe acute respiratory syndrome coronavirus)
E: sars-2 (aka severe acute respiratory syndrome coronavirus 2)
F: sars virus (aka severe acute respiratory syndrome coronavirus)
G: sars coronavirus as
H: None of the above. | [C; C] |
<Instruct>: Given the context 'From initial studies, we hypothesized that attenuated Venezuelan equine encephalitis virus (VEE) replicon particle (VRP) vaccine glycoproteins mediated vaccine failure in the aged.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [venezuelan equine encephalitis virus; vee]
<Options>: A: equine encephalosis virus (eev) (aka equine encephalosis virus)
B: bovine enterovirus (aka enterovirus e)
C: venezuelan equine encephalitis virus (strain trinidad donkey)
D: equine erythroparvovirus 1
E: venezuelan equine encephalitis virus (strain tc-83)
F: equine abortion virus (aka equid alphaherpesvirus 1)
G: tonate virus (venezuelan equine encephalitis virus iiib) (aka tonate virus)
H: veev (aka venezuelan equine encephalitis virus) (aka venezuelan equine encephalitis virus)
I: venezuelan equine encephalitis virus (strain cpa201)
J: None of the above. | [H; H] |
<Instruct>: Given the context 'From initial studies, we hypothesized that attenuated Venezuelan equine encephalitis virus (VEE) replicon particle (VRP) vaccine glycoproteins mediated vaccine failure in the aged.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [venezuelan equine encephalitis virus; vee]
<Options>: A: venezuelan equine encephalitis virus iv (aka pixuna virus)
B: venezuelan equine encephalitis virus (strain tc-83)
C: equine abortion virus (aka equid alphaherpesvirus 1)
D: bovine enterovirus (aka enterovirus e)
E: equine erythroparvovirus 1
F: vebetovirus
G: venezuelan equine encephalitis virus (strain cpa201)
H: venezuelan equine encephalitis virus (strain trinidad donkey)
I: venezuelan equine encephalitis virus vee (aka venezuelan equine encephalitis virus)
J: None of the above. | [I; I] |
<Instruct>: Given the context 'We then compared the efficacies of vaccines bearing attenuated (VRP(3014)) or wild-type VEE glycoproteins (VRP(3000)) in young and aged mice within novel models of severe SARS-CoV pathogenesis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vee; mice; sars-cov]
<Options>: A: erve virus
B: western wild mouse (aka mus spretus)
C: sars-cov (urbani strain) (aka sars coronavirus urbani)
D: vebetovirus
E: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
F: sars-cov (aka severe acute respiratory syndrome coronavirus)
G: human coronavirus (strain sars) (aka severe acute respiratory syndrome-related coronavirus)
H: bat sars-related coronavirus (aka bat sars-like coronavirus)
I: mus molossinus (aka mus musculus molossinus)
J: sars coronavirus as
K: mus terricolor (earth-colored mouse) (aka mus terricolor)
L: equine abortion virus (aka equid alphaherpesvirus 1)
M: veev (aka venezuelan equine encephalitis virus) (aka venezuelan equine encephalitis virus)
N: veia
O: house mouse (aka mus musculus)
P: None of the above. | [M; O; G] |
<Instruct>: Given the context 'We then compared the efficacies of vaccines bearing attenuated (VRP(3014)) or wild-type VEE glycoproteins (VRP(3000)) in young and aged mice within novel models of severe SARS-CoV pathogenesis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vee; mice; sars-cov]
<Options>: A: severe acute respiratory syndrome-related coronavirus (sars (aka severe acute respiratory syndrome-related coronavirus))
B: sars-cov (aka severe acute respiratory syndrome coronavirus)
C: equine encephalosis virus (eev) (aka equine encephalosis virus)
D: equine abortion virus (aka equid alphaherpesvirus 1)
E: western wild mouse (aka mus spretus)
F: sars-2 (aka severe acute respiratory syndrome coronavirus 2)
G: bat sars-related coronavirus (aka bat sars-like coronavirus)
H: mice (aka mus sp.) (aka mus sp.)
I: mus californicus (aka peromyscus californicus)
J: sars coronavirus as
K: mouse (aka mus musculus)
L: eastern equine encephalomyelitis eee (aka eastern equine encephalitis virus)
M: vee (aka venezuelan equine encephalitis virus) (aka venezuelan equine encephalitis virus)
N: eastern european house mouse (aka mus musculus musculus)
O: equine erythroparvovirus 1
P: None of the above. | [M; K; A] |
<Instruct>: Given the context 'We then compared the efficacies of vaccines bearing attenuated (VRP(3014)) or wild-type VEE glycoproteins (VRP(3000)) in young and aged mice within novel models of severe SARS-CoV pathogenesis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vee; mice; sars-cov]
<Options>: A: mouse (aka mus musculus)
B: bat sars-related coronavirus (aka bat sars-like coronavirus)
C: veia
D: sars coronavirus (aka severe acute respiratory syndrome coronavirus)
E: vebetovirus
F: mice (aka mus sp.) (aka mus sp.)
G: southeastern asian house mouse (aka mus musculus castaneus)
H: venezuelan equine encephalitis virus (veev (aka venezuelan equine encephalitis virus))
I: mus terricolor (earth-colored mouse) (aka mus terricolor)
J: sars-cov (urbani strain) (aka sars coronavirus urbani)
K: eastern equine encephalomyelitis eee (aka eastern equine encephalitis virus)
L: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
M: sars (aka severe acute respiratory syndrome-related coronavirus) (aka severe acute respiratory syndrome-related coronavirus)
N: equine abortion virus (aka equid alphaherpesvirus 1)
O: recombinant sars coronavirus
P: None of the above. | [H; A; M] |
<Instruct>: Given the context 'We then compared the efficacies of vaccines bearing attenuated (VRP(3014)) or wild-type VEE glycoproteins (VRP(3000)) in young and aged mice within novel models of severe SARS-CoV pathogenesis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vee; mice; sars-cov]
<Options>: A: southeastern asian house mouse (aka mus musculus castaneus)
B: mus terricolor (earth-colored mouse) (aka mus terricolor)
C: veia
D: mice (aka mus sp.) (aka mus sp.)
E: sars coronavirus (aka severe acute respiratory syndrome coronavirus)
F: vebetovirus
G: recombinant sars coronavirus
H: eastern equine encephalomyelitis eee (aka eastern equine encephalitis virus)
I: mouse (aka mus musculus)
J: equine abortion virus (aka equid alphaherpesvirus 1)
K: sars-cov (urbani strain) (aka sars coronavirus urbani)
L: venezuelan equine encephalitis virus (veev (aka venezuelan equine encephalitis virus))
M: bat sars-related coronavirus (aka bat sars-like coronavirus)
N: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
O: None of the above. | [L; I; O] |
<Instruct>: Given the context 'Aged animals receiving VRP(3000)-based vaccines were protected from SARS-CoV disease, while animals receiving the VRP(3014)-based vaccines were not.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sars-cov]
<Options>: A: severe acute respiratory syndrome coronavirus (sars coronavirus) (aka severe acute respiratory syndrome coronavirus)
B: bat sars-related coronavirus (aka bat sars-like coronavirus)
C: sars-cov (urbani strain) (aka sars coronavirus urbani)
D: human coronavirus (strain sars) (aka severe acute respiratory syndrome-related coronavirus)
E: sars-2 (aka severe acute respiratory syndrome coronavirus 2)
F: None of the above. | [D] |
<Instruct>: Given the context 'Exploration into the mechanism(s) of successful vaccination in the immunosenescent should aid in the development of successful vaccine strategies for other viral diseases disproportionately affecting the elderly, like West Nile virus, influenza virus, norovirus, or other emerging viruses of the future.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [west nile virus]
<Options>: A: west nile virus lineage 1 (aka west nile virus 1)
B: dengue virus
C: noveria virus
D: west nile virus (wnv (aka west nile virus))
E: nai virus
F: None of the above. | [D] |
<Instruct>: Given the context 'Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hepatitis c virus]
<Options>: A: hepatitis b virus hbv (aka hepatitis b virus)
B: hhav (aka human hepatitis a virus) (aka human hepatitis a virus)
C: hepatitis c viruses (aka hepacivirus)
D: hepatitis c virus hcv (aka hepacivirus hominis)
E: hepatitis a virus (aka hepatovirus a)
F: None of the above. | [D] |
<Instruct>: Given the context 'Hepatitis C virus (HCV) can initiate infection by cell-free particle and cell-cell contact-dependent transmission.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hcv]
<Options>: A: hepatitis c virus (isolate japanese)
B: hepatovirus c
C: hcv-hun (aka hepatitis c virus (isolate hunan))
D: hepatitis c virus (aka hepacivirus hominis)
E: human hepatitis circovirus
F: None of the above. | [D] |
<Instruct>: Given the context 'Cell-to-cell transmission is relatively resistant to anti-HCV glycoprotein monoclonal antibodies and polyclonal immunoglobulin isolated from infected individuals, providing an effective strategy for escaping host humoral immune responses.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [anti-hcv]
<Options>: A: hepatitis c virus 08.80.014
B: human hepatitis virus c hcv (aka hepacivirus hominis)
C: hepatitis c virus (isolate india)
D: hepatitis b virus (subtype adr) (aka hepatitis b virus subtype adr)
E: antichiropus antius
F: None of the above. | [B] |
<Instruct>: Given the context 'Chimeric viruses expressing the structural proteins representing the seven major HCV genotypes demonstrate neutralizing antibody-resistant cell-to-cell transmission.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hcv]
<Options>: A: hepatitis c virus (aka hepacivirus hominis)
B: human hepatitis a virus (hhav (aka human hepatitis a virus))
C: hepatitis c virus (isolate japanese)
D: hepatitis c-like viruses (aka hepacivirus)
E: hepatitis c virus hcv-kf (hepatitis c virus (isolate hcv-kf)) (aka hepatitis c virus hcv-kf)
F: None of the above. | [A] |
<Instruct>: Given the context 'HCV entry is a multistep process involving numerous receptors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hcv]
<Options>: A: human hepatitis a virus (hhav (aka human hepatitis a virus))
B: hcv-h (aka hepatitis c virus (isolate h))
C: human hepatitis circovirus
D: human hepatitis c virus hcv (aka hepacivirus hominis)
E: human hepatitis b virus (aka hepatitis b virus)
F: None of the above. | [D] |
<Instruct>: Given the context 'Reovirus infection or ectopic expression of outer capsid protein micro1 induces apoptosis independently of the cellular proapoptotic proteins Bax and Bak.
Mammalian orthoreoviruses induce apoptosis in vivo and in vitro; however, the specific mechanism by which apoptosis is induced is not fully understood.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mammalian orthoreoviruses]
<Options>: A: mammalian orthoreovirus 5
B: mammalian orthoreovirus
C: avian orthoreovirus (avian reovirus) (aka avian orthoreovirus)
D: orthomarburgvirus
E: mammalian orthoreovirus 3 (reovirus type 3) (aka mammalian orthoreovirus 3)
F: None of the above. | [B] |
<Instruct>: Given the context 'Additionally, mu1- or reovirus-induced release of cytochrome c occurred efficiently in Bax(-/-)Bak(-/-) mouse embryonic fibroblasts (MEFs).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse]
<Options>: A: mus terricolor (earth-colored mouse) (aka mus terricolor)
B: mus famulus (servant mouse) (aka mus famulus)
C: macedonian mouse (aka mus macedonicus)
D: mus molossinus (aka mus musculus molossinus)
E: house mouse (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Chikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoff.
Chikungunya virus (CHIKV) is an arthritogenic mosquito-transmitted alphavirus that is undergoing reemergence in areas around the Indian Ocean.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [chikungunya virus; chikv]
<Options>: A: swine influenza virus
B: culex japonicus (aka aedes japonicus)
C: chibugado virus
D: dengue virus
E: chikungunya virus
F: jiangan virus
G: canya virus
H: chikungunya virus strain senegal 37997
I: None of the above. | [E; E] |
<Instruct>: Given the context 'Chikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoff.
Chikungunya virus (CHIKV) is an arthritogenic mosquito-transmitted alphavirus that is undergoing reemergence in areas around the Indian Ocean.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [chikungunya virus; chikv]
<Options>: A: karelian fever virus
B: chikungunya virus
C: chiba virus
D: chijiahe virus
E: hanyang virus
F: chilibre virus
G: dengue virus
H: chikungunya virus strain nagpur
I: chuzan virus
J: None of the above. | [B; B] |
<Instruct>: Given the context 'Despite the current and potential danger posed by this virus, we know surprisingly little about the induction and evasion of CHIKV-associated antiviral immune responses.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [chikv]
<Options>: A: karelian fever virus
B: culex japonicus (aka aedes japonicus)
C: chiba virus
D: chikungunya virus strain nagpur
E: chikungunya virus
F: None of the above. | [E] |
<Instruct>: Given the context 'With this in mind we investigated innate immune reactions to CHIKV in human fibroblasts, a demonstrable in vivo target of virus replication and spread.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [chikv; human]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: chijiahe virus
C: hunchun nairovirus
D: homo (humans) (aka homo)
E: chikungunya virus
F: chize virus
G: carcharhinus humani
H: human louse (aka pediculus humanus)
I: pediculus humanus corporis (pediculus humanus humanus) (aka pediculus humanus corporis)
J: chiba virus
K: None of the above. | [E; A] |
<Instruct>: Given the context 'With this in mind we investigated innate immune reactions to CHIKV in human fibroblasts, a demonstrable in vivo target of virus replication and spread.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [chikv; human]
<Options>: A: homo (humans) (aka homo)
B: karelian fever virus
C: chize virus
D: human (aka homo sapiens)
E: human louse (aka pediculus humanus)
F: chibugado virus
G: pediculus humanus humanus (aka pediculus humanus corporis)
H: carcharhinus humani
I: chikungunya virus strain nagpur
J: chikungunya virus
K: None of the above. | [J; D] |
<Instruct>: Given the context 'We show that CHIKV infection leads to activation of the transcription factor interferon regulatory factor 3 (IRF3) and subsequent transcription of IRF3-dependent antiviral genes, including beta interferon (IFN-Beta).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [chikv]
<Options>: A: chize virus
B: chikungunya virus
C: canya virus
D: hunchun nairovirus
E: oya virus
F: None of the above. | [B] |
<Instruct>: Given the context 'We further demonstrate that translation of cellular (but not viral) genes is blocked during infection and that although CHIKV is found to trigger inactivation of the translational molecule eukaryotic initiation factor subunit 2alpha by way of the double-stranded RNA sensor protein kinase R, this response is not required for the block to protein synthesis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [chikv]
<Options>: A: crimean-congo hemorrhagic virus (aka orthonairovirus haemorrhagiae)
B: chize virus
C: chijiahe virus
D: culex japonicus (aka aedes japonicus)
E: chikungunya virus
F: None of the above. | [E] |
<Instruct>: Given the context 'We further demonstrate that translation of cellular (but not viral) genes is blocked during infection and that although CHIKV is found to trigger inactivation of the translational molecule eukaryotic initiation factor subunit 2alpha by way of the double-stranded RNA sensor protein kinase R, this response is not required for the block to protein synthesis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [chikv]
<Options>: A: culex japonicus (aka aedes japonicus)
B: crimean-congo hemorrhagic virus (aka orthonairovirus haemorrhagiae)
C: chijiahe virus
D: chize virus
E: None of the above. | [E] |
<Instruct>: Given the context 'Furthermore, overall diminution of cellular RNA synthesis is also observed in the presence of CHIKV and transcription of IRF3-dependent antiviral genes appears specifically blocked late in infection.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [chikv]
<Options>: A: chibugado virus
B: chize virus
C: culex japonicus (aka aedes japonicus)
D: canya virus
E: chikungunya virus
F: None of the above. | [E] |
<Instruct>: Given the context 'We hypothesize that the observed absence of IFN-Beta and antiviral proteins during infection results from an evasion mechanism exhibited by CHIKV that is dependent on widespread shutoff of cellular protein synthesis and a targeted block to late synthesis of antiviral mRNA transcripts.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [chikv]
<Options>: A: chize virus
B: chikungunya virus
C: crimean-congo hemorrhagic fever virus (aka orthonairovirus haemorrhagiae)
D: king virus
E: chibugado virus
F: None of the above. | [B] |
<Instruct>: Given the context 'Dominant inhibition of Akt/protein kinase B signaling by the matrix protein of a negative-strand RNA virus.
Vesicular stomatitis virus (VSV) is a rhabdovirus that alters host nuclear and cytoplasmic function upon infection.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vesicular stomatitis virus; vsv]
<Options>: A: sunguru virus
B: vsav (aka vesicular stomatitis alagoas virus) (aka vesicular stomatitis alagoas virus)
C: vesicular stomatitis indiana virus strain glasgow (vesicular stomatitis virus (serotype indiana / strain glasgow)) (aka vesicular stomatitis indiana virus strain glasgow)
D: vsiv (aka vesicular stomatitis indiana virus) (aka vesicular stomatitis indiana virus)
E: swine vesicular disease virus (strain ukg/27/72)
F: vesicular stomatitis virus vsv (aka vesicular stomatitis virus)
G: vesicular stomatitis virus (serotype new jersey / strain missouri)
H: vesicular stomatitis indiana virus (strain 94gub central america)
I: swine vesicular disease virus (strain h/3 '76)
J: None of the above. | [F; F] |
<Instruct>: Given the context 'Dominant inhibition of Akt/protein kinase B signaling by the matrix protein of a negative-strand RNA virus.
Vesicular stomatitis virus (VSV) is a rhabdovirus that alters host nuclear and cytoplasmic function upon infection.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vesicular stomatitis virus; vsv]
<Options>: A: gran virus
B: vesicular stomatitis virus vsv (aka vesicular stomatitis virus)
C: avisivirus
D: swine vesicular disease virus (strain h/3 '76)
E: vesicular stomatitis indiana virus strain glasgow (vesicular stomatitis virus (serotype indiana / strain glasgow)) (aka vesicular stomatitis indiana virus strain glasgow)
F: vesicular stomatitis indiana virus (strain 85clb south america)
G: swine vesicular disease virus (strain ukg/27/72)
H: vesicular stomatitis virus (serotype new jersey / strain missouri)
I: vesicular stomatitis alagoas virus (vsav (aka vesicular stomatitis alagoas virus))
J: None of the above. | [B; B] |
<Instruct>: Given the context 'We have investigated the effect of VSV infection on cellular signaling through the phosphatidylinositol-3 kinase (PI3k)/Akt signaling pathway.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vsv]
<Options>: A: swinepox virus
B: vesicular stomatitis indiana virus (strain 98coe north america)
C: sunguru virus
D: swine vesicular disease virus
E: vesicular stomatitis virus vsv (aka vesicular stomatitis virus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Akt phosphorylation at both threonine 308 (Thr308) and serine 473 (Ser473) was inhibited in cells infected with VSV.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vsv]
<Options>: A: swine vesicular exanthema virus (aka vesicular exanthema of swine virus)
B: vesicular stomatitis indiana virus (strain 94gub central america)
C: vesicular stomatitis virus vsv (aka vesicular stomatitis virus)
D: vesicular stomatitis virus (serotype new jersey / strain missouri)
E: sunguru virus
F: None of the above. | [C] |
<Instruct>: Given the context 'These data illustrate that VSV utilizes a novel mechanism to alter this central player in cell signaling and oncogenesis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vsv]
<Options>: A: vesicular stomatitis alagoas virus (vsav (aka vesicular stomatitis alagoas virus))
B: swine vesicular disease virus
C: south river virus (sorv (aka south river virus))
D: vesicular stomatitis virus, vsv (aka vesicular stomatitis virus)
E: swinepox virus
F: None of the above. | [D] |
<Instruct>: Given the context 'It also suggests an inside-out model of signal transduction where VSV interruption of nuclear events has a rapid and significant effect on membrane signaling events.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vsv]
<Options>: A: sunguru virus
B: gran virus
C: vesicular stomatitis indiana virus (vsiv (aka vesicular stomatitis indiana virus))
D: vesicular stomatitis virus vsv (aka vesicular stomatitis virus)
E: sorv (aka south river virus) (aka south river virus)
F: None of the above. | [D] |
<Instruct>: Given the context 'It also suggests an inside-out model of signal transduction where VSV interruption of nuclear events has a rapid and significant effect on membrane signaling events.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vsv]
<Options>: A: sunguru virus
B: vesicular stomatitis indiana virus (vsiv (aka vesicular stomatitis indiana virus))
C: sorv (aka south river virus) (aka south river virus)
D: gran virus
E: None of the above. | [E] |
<Instruct>: Given the context 'Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hiv-1]
<Options>: A: hiv (aka human immunodeficiency virus 1) (aka human immunodeficiency virus 1)
B: human immunodeficiency virus type 1 (kb-1 isolate)
C: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus)
D: None of the above. | [A] |
<Instruct>: Given the context 'The HIV-1 protein Vpu counteracts the antiviral activity of the innate restriction factor BST-2/tetherin by a mechanism that partly depends on its interaction with Beta-TrCP, a substrate adaptor for an SCF (Skp-Cullin 1-F box) E3 ubiquitin ligase complex.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hiv-1]
<Options>: A: human immunodeficiency virus type i hiv-1 (aka human immunodeficiency virus 1)
B: human immunodeficiency virus type 1 (kb-1 isolate)
C: aids virus (aka human immunodeficiency virus)
D: None of the above. | [A] |
<Instruct>: Given the context 'Varicella-zoster virus glycoprotein E is a critical determinant of virulence in the SCID mouse-human model of neuropathogenesis.
Varicella-zoster virus (VZV) is a neurotropic alphaherpesvirus.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [varicella-zoster virus; human; vzv]
<Options>: A: sphaeria humana (aka sordaria humana)
B: simian varicella virus (aka cercopithecine alphaherpesvirus 9)
C: neanderthal man (aka homo sapiens neanderthalensis)
D: human body louse (aka pediculus humanus corporis)
E: varicellaria
F: human alphaherpesvirus 3 (vzv (aka human alphaherpesvirus 3))
G: rabbitpox virus
H: vaccinia virus vv (aka vaccinia virus)
I: homo sapiens (human) (aka homo sapiens)
J: vixey virus
K: smallpox (aka variola virus)
L: swinepox virus
M: gymnopleurus humanus
N: smallpox virus (aka variola virus)
O: None of the above. | [F; I; F] |
<Instruct>: Given the context 'Varicella-zoster virus glycoprotein E is a critical determinant of virulence in the SCID mouse-human model of neuropathogenesis.
Varicella-zoster virus (VZV) is a neurotropic alphaherpesvirus.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [varicella-zoster virus; human; vzv]
<Options>: A: great apes (aka hominidae)
B: varicellaria
C: carcharhinus humani
D: quailpox virus
E: smallpox (aka variola virus)
F: herpesvirus pan (aka panine gammaherpesvirus 1)
G: human alphaherpesvirus 3 (vzv (aka human alphaherpesvirus 3))
H: vaccinia virus (vaccinia virus vv) (aka vaccinia virus)
I: sphaeria humana (aka sordaria humana)
J: variola
K: gymnopleurus humanus
L: zebra herpesvirus
M: human (aka homo sapiens)
N: None of the above. | [G; M; G] |
<Instruct>: Given the context 'Varicella-zoster virus glycoprotein E is a critical determinant of virulence in the SCID mouse-human model of neuropathogenesis.
Varicella-zoster virus (VZV) is a neurotropic alphaherpesvirus.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [varicella-zoster virus; human; vzv]
<Options>: A: sphaeria humana (aka sordaria humana)
B: homo sapiens (human) (aka homo sapiens)
C: variola
D: gymnopleurus humanus
E: homo (humans) (aka homo)
F: smallpox virus (aka variola virus)
G: cardium humanum (aka glossus humanus)
H: simian varicella virus (aka cercopithecine alphaherpesvirus 9)
I: varicellaria
J: rabbitpox virus
K: human alphaherpesvirus 3 (vzv (aka human alphaherpesvirus 3))
L: quailpox virus
M: human herpesvirus 3 strain dumas (varicella-zoster virus (strain dumas)) (aka human herpesvirus 3 strain dumas)
N: None of the above. | [K; B; K] |
<Instruct>: Given the context 'VZV infection of human dorsal root ganglion (DRG) xenografts in immunodeficient mice models the infection of sensory ganglia.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vzv; human]
<Options>: A: varicellaria
B: rabbitpox virus
C: human orf virus
D: varicella-zoster virus (aka human alphaherpesvirus 3)
E: cardium humanum (aka glossus humanus)
F: human body louse (aka pediculus humanus corporis)
G: hominidae (great apes) (aka hominidae)
H: humans (aka homo)
I: human (aka homo sapiens)
J: gallid herpesvirus
K: None of the above. | [D; I] |
<Instruct>: Given the context 'VZV infection of human dorsal root ganglion (DRG) xenografts in immunodeficient mice models the infection of sensory ganglia.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vzv; human]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: varicella zoster virus (aka human alphaherpesvirus 3)
C: hominidae (great apes) (aka hominidae)
D: neandertal man (aka homo sapiens neanderthalensis)
E: human orf virus
F: simian varicella virus (aka cercopithecine alphaherpesvirus 9)
G: macrobiotus sapiens
H: pediculus humanus humanus (aka pediculus humanus corporis)
I: zebra herpesvirus
J: varicella-zoster virus (strain dumas) (aka human herpesvirus 3 strain dumas)
K: None of the above. | [B; A] |
<Instruct>: Given the context 'We examined DRG infection with recombinant VZV (recombinant Oka [rOka]) and the following gE mutants: gEDelta27-90, gEDeltaCys, gE-AYRV, and gE-SSTT.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vzv]
<Options>: A: simian varicella virus (aka cercopithecine alphaherpesvirus 9)
B: human herpesvirus 3 strain dumas (varicella-zoster virus (strain dumas)) (aka human herpesvirus 3 strain dumas)
C: rabbitpox virus
D: smallpox virus (aka variola virus)
E: varicella-zoster virus (aka human alphaherpesvirus 3)
F: None of the above. | [E] |
<Instruct>: Given the context 'Since neural cells express IDE, the gE/IDE interaction was dispensable for VZV neurotropism.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vzv]
<Options>: A: varicella zoster virus vzv (aka human alphaherpesvirus 3)
B: human herpesvirus 3 vzv-32
C: simian varicella virus (aka cercopithecine alphaherpesvirus 9)
D: gallid herpesvirus
E: zebra herpesvirus
F: None of the above. | [F] |
<Instruct>: Given the context 'These experiments suggest that the gE interaction with cellular IDE, gE targeting to TGN sites of virion envelopment, and phosphorylation at SSTT are dispensable for VZV DRG infection, whereas the gE/gI interaction is critical for VZV neurovirulence.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vzv]
<Options>: A: human orf virus
B: varicella-zoster virus (strain dumas) (aka human herpesvirus 3 strain dumas)
C: simian varicella virus (aka cercopithecine alphaherpesvirus 9)
D: smallpox virus (aka variola virus)
E: human herpesvirus 3 vzv-32
F: None of the above. | [F] |
<Instruct>: Given the context 'Domain structure of Lassa virus L protein.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [lassa virus]
<Options>: A: swine influenza virus
B: lasallevirus
C: lassa virus (aka mammarenavirus lassaense)
D: langya virus (langya henipavirus) (aka langya virus)
E: swinepox virus
F: None of the above. | [C] |
<Instruct>: Given the context 'This study aimed at providing evidence for the domain structure of L protein by combining bioinformatics with a stepwise mutagenesis approach using the Lassa virus minireplicon system.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [lassa virus]
<Options>: A: landiras virus
B: lassa virus (aka mammarenavirus lassaense)
C: lasallevirus
D: la crosse virus (bunyavirus la crosse) (aka la crosse virus)
E: lasigmu virus
F: None of the above. | [B] |
<Instruct>: Given the context 'This study aimed at providing evidence for the domain structure of L protein by combining bioinformatics with a stepwise mutagenesis approach using the Lassa virus minireplicon system.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [lassa virus]
<Options>: A: lasigmu virus
B: landiras virus
C: la crosse virus (bunyavirus la crosse) (aka la crosse virus)
D: lasallevirus
E: None of the above. | [E] |
<Instruct>: Given the context 'Insertion of 5 or 10 amino acid residues was tolerated at seven sites (S407, G446, G467, G774, G939, S1952, and V2074 in Lassa virus AV).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [lassa virus av]
<Options>: A: grapevine virus a
B: little sussex virus
C: lassa virus ga391 (lassa virus (strain ga391)) (aka lassa virus ga391)
D: australian bat lyssavirus (aka lyssavirus australis)
E: lassa virus (aka mammarenavirus lassaense)
F: None of the above. | [E] |
<Instruct>: Given the context 'In conclusion, this study demonstrates two interdomain linkers in Lassa virus L protein, at G467 and G939, suggesting that L protein is composed of at least three structural domains spanning residues 1 to 467, 467 to 939, and 939 to 2220.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [lassa virus]
<Options>: A: swine pneumovirus
B: little sussex virus
C: lassa virus (aka mammarenavirus lassaense)
D: swine orthopneumovirus
E: lasallevirus
F: None of the above. | [C] |
<Instruct>: Given the context 'Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus capsid destabilization.
Human immunodeficiency virus type 1 (HIV-1) infection is dependent on the proper disassembly of the viral capsid, or "uncoating," in target cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human immunodeficiency virus type 1; hiv-1]
<Options>: A: human immunodeficiency virus type 1 (kb-1 isolate)
B: human immunodeficiency virus (hiv (aka human immunodeficiency virus))
C: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus)
D: human immunodeficiency virus type 1 (new york-5 isolate)
E: hiv1 (aka human immunodeficiency virus 1) (aka human immunodeficiency virus 1)
F: None of the above. | [E; E] |
<Instruct>: Given the context 'Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus capsid destabilization.
Human immunodeficiency virus type 1 (HIV-1) infection is dependent on the proper disassembly of the viral capsid, or "uncoating," in target cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human immunodeficiency virus type 1; hiv-1]
<Options>: A: hiv1 (aka human immunodeficiency virus 1) (aka human immunodeficiency virus 1)
B: human immunodeficiency virus type 1 (kb-1 isolate)
C: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus)
D: human immunodeficiency virus type 1 (new york-5 isolate)
E: aids virus (aka human immunodeficiency virus)
F: None of the above. | [A; A] |
<Instruct>: Given the context 'The HIV-1 capsid consists of a conical multimeric complex of the viral capsid protein (CA) arranged in a hexagonal lattice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hiv-1]
<Options>: A: aids virus (aka human immunodeficiency virus)
B: human immunodeficiency virus hiv-1 (aka human immunodeficiency virus 1)
C: human immunodeficiency virus type 1 (kb-1 isolate)
D: None of the above. | [B] |
<Instruct>: Given the context 'We describe here the mechanism of action of a small molecule HIV-1 inhibitor, PF-3450074 (PF74), which targets CA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hiv-1]
<Options>: A: human immunodeficiency virus type 1 (kb-1 isolate)
B: hiv (aka human immunodeficiency virus 1) (aka human immunodeficiency virus 1)
C: aids virus (aka human immunodeficiency virus)
D: None of the above. | [B] |
<Instruct>: Given the context 'PF74 acts at an early stage of HIV-1 infection and inhibits reverse transcription in target cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hiv-1]
<Options>: A: human immunodeficiency virus (hiv (aka human immunodeficiency virus))
B: hiv-1 (aka human immunodeficiency virus 1)
C: human immunodeficiency virus type 1 (kb-1 isolate)
D: None of the above. | [B] |
<Instruct>: Given the context 'We show that PF74 binds specifically to HIV-1 particles, and substitutions in CA that confer resistance to the compound prevent binding.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hiv-1]
<Options>: A: human immunodeficiency virus type 1 hiv-1 (aka human immunodeficiency virus 1)
B: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus)
C: human immunodeficiency virus type 1 (kb-1 isolate)
D: None of the above. | [A] |
<Instruct>: Given the context 'We show that PF74 binds specifically to HIV-1 particles, and substitutions in CA that confer resistance to the compound prevent binding.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hiv-1]
<Options>: A: human immunodeficiency virus type 1 (kb-1 isolate)
B: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus)
C: None of the above. | [C] |
<Instruct>: Given the context 'A single point mutation in CA that stabilizes the HIV-1 core also conferred strong resistance to the virus without inhibiting compound binding.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hiv-1]
<Options>: A: human immunodeficiency virus type 1 (kb-1 isolate)
B: human immunodeficiency virus (hiv (aka human immunodeficiency virus))
C: human immunodeficiency virus type 1 hiv1 (aka human immunodeficiency virus 1)
D: None of the above. | [C] |
<Instruct>: Given the context 'Treatment of HIV-1 particles or purified cores with PF74 destabilized the viral capsid in vitro.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hiv-1]
<Options>: A: aids virus (aka human immunodeficiency virus 1)
B: human immunodeficiency virus (hiv (aka human immunodeficiency virus))
C: human immunodeficiency virus type 1 (kb-1 isolate)
D: None of the above. | [A] |
<Instruct>: Given the context 'Furthermore, the compound induced the rapid dissolution of the HIV-1 capsid in target cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hiv-1]
<Options>: A: human immunodeficiency virus type 1 hiv 1 (aka human immunodeficiency virus 1)
B: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus)
C: human immunodeficiency virus type 1 (kb-1 isolate)
D: None of the above. | [A] |
<Instruct>: Given the context 'PF74 antiviral activity was promoted by binding of the host protein cyclophilin A to the HIV-1 capsid, and PF74 and cyclosporine exhibited mutual antagonism.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hiv-1]
<Options>: A: aids virus (aka human immunodeficiency virus)
B: human immunodeficiency virus 1 (human immunodeficiency virus type 1, hiv-1) (aka human immunodeficiency virus 1)
C: human immunodeficiency virus type 1 (kb-1 isolate)
D: None of the above. | [B] |
<Instruct>: Given the context 'Our data suggest that PF74 triggers premature HIV-1 uncoating in target cells, thereby mimicking the activity of the retrovirus restriction factor TRIM5alpha.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hiv-1]
<Options>: A: hiv-1 (aka human immunodeficiency virus 1)
B: aids virus (aka human immunodeficiency virus)
C: human immunodeficiency virus type 1 (kb-1 isolate)
D: None of the above. | [A] |
<Instruct>: Given the context 'This study highlights uncoating as a step in the HIV-1 life cycle that is susceptible to small molecule intervention.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hiv-1]
<Options>: A: human immunodeficiency virus type 1 (kb-1 isolate)
B: human immunodeficiency virus type 1, hiv-1 (aka human immunodeficiency virus 1)
C: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus)
D: None of the above. | [B] |
<Instruct>: Given the context 'Mice lacking both B7.1 and B7.2 showed reduced early expansion of CMV-specific CD4 T cells, consequently allowing for enhanced levels of persistent virus replication.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: western wild mouse (aka mus spretus)
B: mus domesticus (aka mus musculus domesticus)
C: mouse (aka mus musculus)
D: mus famulus (servant mouse) (aka mus famulus)
E: mus californicus (aka peromyscus californicus)
F: None of the above. | [C] |
<Instruct>: Given the context 'Novel F141L pre-S2 mutation in hepatitis B virus increases the risk of hepatocellular carcinoma in patients with chronic genotype C infections.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hepatitis b virus]
<Options>: A: hepatitis gb virus b (aka gb virus-b)
B: hepatovirus b
C: hepatitis b virus (hbv) (aka hepatitis b virus)
D: dhbv (aka duck hepatitis b virus) (aka duck hepatitis b virus)
E: human hepatitis a virus (hhav (aka human hepatitis a virus))
F: None of the above. | [C] |
<Instruct>: Given the context 'Several lines of evidence have suggested that some naturally occurring mutations of hepatitis B virus (HBV) play a critical role in hepatocellular carcinoma (HCC).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hepatitis b virus; hbv]
<Options>: A: horseshoe bat hepatitis b virus (hbhbv) (aka horseshoe bat hepatitis b virus)
B: hbhbv (aka horseshoe bat hepatitis b virus)
C: hepatitis b virus genotype b (hbv genotype b) (aka hepatitis b virus genotype b)
D: hepatitis b virus (hbv) (aka hepatitis b virus)
E: hepatitis gb virus b (aka gb virus-b)
F: hepatitis b-type viruses (aka hepadnaviridae)
G: hepatitis b virus (subtype ayw) (aka hepatitis b virus subtype ayw)
H: duck hepatitis b virus (dhbv (aka duck hepatitis b virus))
I: human hepatitis a virus (hhav (aka human hepatitis a virus))
J: None of the above. | [D; D] |
<Instruct>: Given the context 'Several lines of evidence have suggested that some naturally occurring mutations of hepatitis B virus (HBV) play a critical role in hepatocellular carcinoma (HCC).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hepatitis b virus; hbv]
<Options>: A: hbhbv (aka horseshoe bat hepatitis b virus)
B: human hepatitis a virus (hhav (aka human hepatitis a virus))
C: duck hepatitis b virus (dhbv (aka duck hepatitis b virus))
D: hepatitis b virus (subtype ayw) (aka hepatitis b virus subtype ayw)
E: hepatitis b virus genotype b (hbv genotype b) (aka hepatitis b virus genotype b)
F: hepatitis gb virus b (aka gb virus-b)
G: horseshoe bat hepatitis b virus (hbhbv) (aka horseshoe bat hepatitis b virus)
H: hepatitis b-type viruses (aka hepadnaviridae)
I: None of the above. | [I; I] |
<Instruct>: Given the context 'Several lines of evidence have suggested that some naturally occurring mutations of hepatitis B virus (HBV) play a critical role in hepatocellular carcinoma (HCC).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hepatitis b virus; hbv]
<Options>: A: human hepatitis a virus (hhav (aka human hepatitis a virus))
B: hepatitis b virus (human hepatitis b virus hbv) (aka hepatitis b virus)
C: hbv-i (aka hepatitis b virus genotype i)
D: hepatitis b-type viruses (aka hepadnaviridae)
E: hepatitis b virus (subtype ayw) (aka hepatitis b virus subtype ayw)
F: hepatitis a virus (aka hepatovirus a)
G: gb virus-b (hepatitis gb virus b) (aka gb virus-b)
H: non-human hbv
I: None of the above. | [B; B] |
<Instruct>: Given the context 'Poliovirus-mediated disruption of cytoplasmic processing bodies.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [poliovirus]
<Options>: A: poliovirus (aka enterovirus c)
B: p virus
C: murine poliovirus (aka theiler's encephalomyelitis virus)
D: human poliovirus 1 (aka poliovirus 1)
E: human poliovirus 2 (aka poliovirus 2)
F: None of the above. | [A] |
<Instruct>: Given the context 'Poliovirus (PV) is a plus-strand RNA virus containing a genome that is a functional mRNA; thus, we investigated if PV antagonizes the processes that lead to formation of these structures.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [poliovirus; pv]
<Options>: A: poliovirus (aka enterovirus c)
B: poliovirus 2 (human poliovirus type 2) (aka poliovirus 2)
C: porcine parvovirus (ppv (aka porcine parvovirus))
D: human poliovirus 3 (aka poliovirus 3)
E: unidentified poliovirus
F: penalva
G: murine poliovirus (aka theiler's encephalomyelitis virus)
H: transfection vector pvv
I: pestivirus bovis (pestivirus a) (aka pestivirus bovis)
J: transformation vector pv1
K: None of the above. | [A; A] |
<Instruct>: Given the context 'Poliovirus (PV) is a plus-strand RNA virus containing a genome that is a functional mRNA; thus, we investigated if PV antagonizes the processes that lead to formation of these structures.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [poliovirus; pv]
<Options>: A: murine poliovirus (aka theiler's encephalomyelitis virus)
B: poliovirus (aka enterovirus c)
C: porcine parvovirus (ppv (aka porcine parvovirus))
D: pestivirus o
E: unidentified poliovirus
F: pestivirus
G: porcine pestivirus
H: human poliovirus 1 (aka poliovirus 1)
I: veprecula
J: p virus
K: None of the above. | [B; B] |
<Instruct>: Given the context 'We have previously shown that PV infection inhibits the ability of cells to form stress granules by cleaving RasGAP-SH3-binding protein (G3BP).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [pv]
<Options>: A: malaria parasite p. vivax (aka plasmodium vivax)
B: pestivirus bovis (pestivirus a) (aka pestivirus bovis)
C: plasmid ppv
D: porcine pestivirus
E: pv1 (aka poliovirus 1) (aka poliovirus 1)
F: None of the above. | [F] |
<Instruct>: Given the context 'Here, we show that P bodies are also disrupted during PV infection in cells by 4 h postinfection.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [pv]
<Options>: A: pestivirus o
B: porcine parvovirus (ppv (aka porcine parvovirus))
C: veprecula
D: pv1 (aka poliovirus 1) (aka poliovirus 1)
E: pestivirus
F: None of the above. | [F] |
<Instruct>: Given the context 'Two factors involved in 5'-end mRNA decapping and degradation, Xrn1 and Dcp1a, and the 3' deadenylase complex component Pan3 underwent accelerated degradation during infection, and Dcp1a may be a direct substrate of PV 3C proteinase.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [pv]
<Options>: A: pestivirus c (aka pestivirus suis)
B: veprecula
C: perrin park virus
D: pestivirus
E: penalva
F: None of the above. | [F] |
<Instruct>: Given the context 'Several other key factors proposed to be essential for P body formation, GW182, Edc3, and Edc4, were unaffected by poliovirus infection.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [poliovirus]
<Options>: A: poliovirus type 1 (aka poliovirus 1)
B: human poliovirus type 3 (aka poliovirus 3)
C: poliovirus (aka enterovirus c)
D: murine poliovirus (aka theiler's encephalomyelitis virus)
E: poliovirus 2 (human poliovirus type 2) (aka poliovirus 2)
F: None of the above. | [C] |
<Instruct>: Given the context 'The magnitude of local immunity in the lungs of mice induced by live attenuated influenza vaccines is determined by local viral replication and induction of cytokines.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus domesticus (aka mus musculus domesticus)
B: mus famulus (servant mouse) (aka mus famulus)
C: mus macedonicus (macedonian mouse) (aka mus macedonicus)
D: house mouse (aka mus musculus)
E: mus terricolor (earth-colored mouse) (aka mus terricolor)
F: None of the above. | [D] |
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