title stringlengths 0 221 | text stringlengths 0 375k |
|---|---|
Skin signs resembling vascular acrosyndromes during the COVID‐19 outbreak in Italy | We have read with great interest Dr Estébanez article regarding the case of a 28-year-old woman affected by COVID-19, presenting confluent erythematous-yellowish papules at both heels. After three days, the lesions persisted and became hardened erythematous plaques. |
Current pharmacological treatments for COVID‐19: What's next? | Since December 2019 SARS‐Cov‐2 was found responsible for the disease COVID‐19, which has spread worldwide. No specific therapies/vaccines are yet available for the treatment of COVID‐19. Drug repositioning may offer a strategy and a number of drugs have been repurposed, including lopinavir/ritonavir, remdesivir, favipi... |
Distant learning of BLS amid the COVID-19 pandemic: Influence of the outbreak on lay trainees’ willingness to attempt CPR, and the motivating effect of the training | |
The economics of Africa's floriculture air-cargo supply chain | This article examines the economics of Africa's emerging air cargo supply chains, taking floriculture as a case study. Floriculture is an important employer, and earner of foreign exchange for several regions of central/southern and eastern Africa including more recently Ethiopia. Air transportation often plays a criti... |
Clinical consensus recommendations regarding non-invasive respiratory support in the adult patient with acute respiratory failure secondary to SARS-CoV-2 infection | Abstract Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by a newly emergent coronavirus, that was first recognized in Wuhan, China, in December 2019. Currently, the World Health Organization (WHO) has defined the infection as a global pandemic and there is a health and social emergency for ... |
Synthesis, antimicrobial and cytotoxic activities of some novel thiazole clubbed 1,3,4-oxadiazoles | Abstract A series of thiazole clubbed 1,3,4-oxadiazole derivatives (5a–l) have been synthesized and characterized by IR, 1H NMR, 13C NMR and mass spectral analysis. Synthesized compounds were evaluated for their antimicrobial and cytotoxic activities. The results indicated that, compounds 5c and 5i exhibited the most p... |
Toxicologic and comparative clinical pathology externship scholarships broaden clinical pathology resident training opportunities | |
Respiratory tract infection-related healthcare utilisation in children with Down’s syndrome | PURPOSE: Children with Down’s syndrome (DS) are prone to respiratory tract infections (RTIs) due to anatomical variation, immune system immaturity and comorbidities. However, evidence on RTI-related healthcare utilisation, especially in primary care, is incomplete. In this retrospective cohort study, we use routinely c... |
Global Access to Handwashing: Implications for COVID-19 Control in Low-Income Countries | BACKGROUND: Low-income countries have reduced health care system capacity and are therefore at risk of substantially higher COVID-19 case fatality rates than those currently seen in high-income countries. Handwashing is a key component of guidance to reduce transmission of the SARS-CoV-2 virus, responsible for the COVI... |
Clinical characteristics and viral etiologies of outpatients with acute respiratory infections in Huzhou of China: a retrospective study | BACKGROUND: Viruses are commonly found in patients with acute respiratory infections (ARIs). However, the viral etiologies and clinical characteristics of outpatients with ARIs are poorly understood in China. Here, we identified the viral etiologies in outpatients with ARIs in Huzhou, China. RESULTS: Our results indica... |
Genome-wide analysis of codon usage bias in Bovine Coronavirus | BACKGROUND: Bovine coronavirus (BCoV) belong to the genus Betacoronavirus of the family Coronaviridae. BCoV are widespread around the world and cause enteric or respiratory infections among cattle, leading to important economic losses to the beef and dairy industry worldwide. To study the relation of codon usage among ... |
Genetic Variation of the Human α-2-Heremans-Schmid Glycoprotein (AHSG) Gene Associated with the Risk of SARS-CoV Infection | Genetic background may play an important role in the process of SARS-CoV infection and SARS development. We found several proteins that could interact with the nucleocapsid protein of the SARS coronavirus (SARS-CoV). α-2-Heremans-Schmid Glycoprotein (AHSG), which is required for macrophage deactivation by endogenous ca... |
Contaminant source identification within a building: Toward design of immune buildings | Abstract The level of protection of a building against the intentional or accidental release of chemical agents is crucial. Both scenarios could endanger life and safety of the buildings occupants. Equipping buildings with appropriate chemical sensors can alert the building occupants about the contaminant release. The ... |
2020 International Year of the Midwife – an unexpected challenge | |
A24 Application of large-scale sequencing and data analysis to research on emerging infectious diseases | |
Influence of Breed Size, Age, Fecal Quality, and Enteropathogen Shedding on Fecal Calprotectin and Immunoglobulin A Concentrations in Puppies During the Weaning Period | BACKGROUND: Fecal calprotectin and immunoglobulin A (IgA) are markers of intestinal inflammation and immunity in adult dogs. HYPOTHESIS: Fecal calprotectin and IgA concentrations in puppies are not influenced by fecal moisture in puppies but by enteropathogen shedding. ANIMALS: Three hundred and twenty‐four puppies. ME... |
Nature's patterns, unlocked with AI | Smart software could predict the next invasive plant species or disease outbreak |
Viral otitis media | Acute otitis media (AOM) and viral upper respiratory tract infections (URIs) represent the two most common diseases affecting the human population, and account for substantial patient morbidity and health care costs. Epidemiologic and experimental studies suggest that URIs play a causal role in the pathogenesis of AOM.... |
Prevalence and Demographic Correlates of Poor Sleep Quality Among Frontline Health Professionals in Liaoning Province, China During the COVID-19 Outbreak | BACKGROUND: Little empirical evidence is known about the sleep quality of frontline health professionals working in isolation units or hospitals during the novel coronavirus disease (COVID-19) outbreak in China. This study thus aimed to examine the prevalence of poor sleep quality and its demographic and correlates amo... |
The NS1 protein of H5N6 feline influenza virus inhibits feline beta interferon response by preventing NF-κB and IRF3 activation | Abstract Despite the apparent lack of a feline influenza virus lineage, cats are susceptible to infection by influenza A viruses. Here, we characterized in vitro A/feline/Guangdong/1/2015, an H5N6 avian influenza virus recently isolated from cats. A/feline/Guangdong/1/2015 replicated to high titers and caused CPE in fe... |
Characteristics of flavonoids as potent MERS‐CoV 3C‐like protease inhibitors | Middle East respiratory syndrome‐coronavirus (MERS‐CoV) is a zoonotic virus transmitted between animals and human beings. It causes MERS with high mortality rate. However, no vaccine or specific treatment is currently available. Since antiviral activity of some flavonoids is known, we applied a flavonoid library to pro... |
Emerging challenges in the design of selective substrates, inhibitors and activity‐based probes for indistinguishable proteases | Proteases are enzymes that hydrolyze the peptide bond of peptide substrates and proteins. Despite significant progress in recent years, one of the greatest challenges in the design and testing of substrates, inhibitors and activity‐based probes for proteolytic enzymes is achieving specificity toward only one enzyme. Th... |
STAFF AND PATIENTS’ PROTECTION IN RADIATION ONCOLOGY DEPARTMENTS DURING COVID-19 PANDEMIC | |
South Korea’s COVID-19 Infection Status: From the Perspective of Re-positive Test Results After Viral Clearance Evidenced by Negative Test Results | Coronavirus disease (COVID-19) started to occur in South Korea by means of inflow of the virus from abroad, when a case from Wuhan, China, was first confirmed on January 19, 2020. Although South Korea has drastically reduced the number of new confirmed cases and is stabilizing the situation with its exemplary disease p... |
Physiological advantages of children against COVID‐19 | We read the editorial by Dr. Brodin with great interest, which is discussing why COVID-19 appears to be so mild in children(1). The author discussed the potential theories that could explain why children have a lower incidence and milder clinical manifestations than adults. Additionally to the theories mentioned by the... |
Analysis of the humoral immune responses among cynomolgus macaque naturally infected with Reston virus during the 1996 outbreak in the Philippines | BACKGROUND: Ebolaviruses induce lethal viral hemorrhagic fevers (VHFs) in humans and non-human primates, with the exceptions of Reston virus (RESTV), which is not pathogenic for humans. In human VHF cases, extensive analyses of the humoral immune responses in survivors and non-survivors have shown that the IgG response... |
Describing the Chinese HIV Surveillance System and the Influences of Political Structures and Social Stigma | China’s public health surveillance system for HIV was established in late 1980s and has evolved significantly during the past three decades. With the gradually changing mode of HIV transmission from sharing of intravenous injecting equipment to sexual exposure and the rapid spread of HIV infection among Chinese homosex... |
Detection and molecular characterization of porcine toroviruses in Korea | This study examined the prevalence and genetic diversity of the porcine torovirus (PToV) in Korea. Of 295 samples, 19 (6.4%) samples tested positive for PToVs by RT-PCR. A low nucleotide sequence identity of the partial S gene was detected among the Korean PToVs (73.5%) and between the Korean and European PToVs (74.0%)... |
Translational control by viral proteinases | Abstract Most RNA viruses have evolved strategies to regulate cellular translation in order to promote preferential expression of the viral genome. Positive strand RNA viruses express large portions, or all of their proteome via translation of large polyproteins that are processed by embedded viral proteinases or host ... |
The Association of Cardiovascular Diseases and Diabetes Mellitus with COVID-19 (SARS-CoV-2) and Their Possible Mechanisms | Coronavirus disease 2019 (COVID-19) has become a global concern and public health issue due to its higher infection and mortality rate; particularly, the risk is very higher among the patients who have cardiovascular diseases (CVD) and/or diabetes mellitus (DM). In this review, we analyzed the recently published litera... |
Clinical Course and Physiotherapy Intervention in 9 patients with COVID-19 | |
Absage von Impfungen wegen COVID-19 | Infolge der Coronapandemie könnte es in Deutschland zu Impflücken kommen. Darauf deutet eine Befragung von 1.000 Menschen im Rahmen des COVID-19 Snapshot Monitoring (COSMO) hin, an dem sich u. a. das RKI beteiligt. |
Human Coronavirus-NL63 infections in Korean children, 2004–2006 | Abstract Background Human coronavirus-NL63 (HCoV-NL63) has been isolated from children with respiratory tract infections and its prevalence in Korea has not been reported. Objectives This study was designed to investigate the presence and the clinical features of HCoV-NL63 during two winter seasons. Study design During... |
Antigenic structure of transmissible gastroenteritis virus nucleoprotein | Abstract A group of 11 monoclonal antibodies (MAbs) raised against transmissible gastroenteritis virus (TGEV) was used to study the antigenic structure of the virus nucleoprotein (N). To identify the regions recognized by MAbs, DNA fragments derived from the N-coding region of the TGEV strain FS772/70 were cloned into ... |
Affections de la rétine | Résumé Après un rappel des notions d’anatomie, de physiologie et l’énoncé des définitions qu’il est indispensable de connaître pour aborder l’étude de la pathologie rétinienne, les affections suivantes sont présentées dans les différentes espèces de mammifères domestiques (carnivores, équidés, ruminants et porcins) : d... |
Beyond tropes: Towards a new image of nursing in the wake of COVID‐19 | On 21st December 2019 the first cluster of patients with 'pneumonia of an unknown cause', which was subsequently identified as a coronavirus or 'Covid-19', were identified in Wuhan, China. As we now know the virus spread rapidly around the globe and on March 11th the World Health Organization (WHO) declared the virus a... |
Manejo Emocional De La Crisis Sanitaria Ante El Coronavirus: Una Revisión Narrativa | Abstract Objective: To make a synthesis of the available scientific evidence in the emotional management of the declared health crisis in the face of coronavirus. Methods: A bibliographic search was made, without date limit, in Medline, CINAHL, PsycINFO, Scopus and Web of Science databases using the following keywords:... |
Rhinovirus : des pathogènes sous-estimés chez les patients en période néonatale | Résumé Introduction Les récents développements des outils de diagnostic virologique ont permis d’identifier les entérovirus et rhinovirus (E/RV) plus aisément. Leur mise en évidence est très fréquente lors d’atteintes des voies aériennes chez l’enfant et leur causalité démontrée. La morbidité néonatale des infections à... |
A cluster randomized clinical trial comparing fit‐tested and non‐fit‐tested N95 respirators to medical masks to prevent respiratory virus infection in health care workers | Please cite this paper as: MacIntyre et al. (2011) A cluster randomized clinical trial comparing fit‐tested and non‐fit‐tested N95 respirators to medical masks to prevent respiratory virus infection in health care workers. Influenza and Other Respiratory Viruses DOI: 10.1111/j.1750‐2659.2010.00198.x. Background We comp... |
Implementing a One Health approach to emerging infectious disease: reflections on the socio-political, ethical and legal dimensions | BACKGROUND: ‘One Health’ represents a call for health researchers and practitioners at the human, animal and environmental interfaces to work together to mitigate the risks of emerging and re-emerging infectious diseases (EIDs). A One Health approach emphasizing inter-disciplinary co-operation is increasingly seen as n... |
Hydroxychloroquine treatment in COVID‐19: a descriptive observational analysis of 30 cases from a single center in Wuhan, China | Hydroxychloroquine (HCQ) garnered scientific attention in early February following publication of reports showing in vitro activity of chloroquine (CQ) against COVID‐19. While studies are mixed on this topic, the therapeutic effect of HCQ or CQ still need more valid clinical evidence. In this descriptive observational ... |
High diagnostic accuracy of the Sysmex XT‐2000iV delta total nucleated cells on effusions for feline infectious peritonitis | BACKGROUND: The ΔWBC (the ratio between DIFF and BASO counts of the Sysmex XT‐2000iV), hereafter defined as ΔTNC (total nucleated cells), is high in effusions due to feline infectious peritonitis (FIP), as cells are entrapped in fibrin clots formed in the BASO reagent. Similar clots form in the Rivalta's test, a method... |
Grippe et voyage | Résumé Pour le voyageur, il existe un risque de contracter des maladies infectieuses pendant le voyage et de les introduire dans des régions non endémiques au retour. La grippe en fournit un exemple classique. L'incidence de la grippe chez les voyageurs reste mal connue. Nombre d'épidémies de grippe ont cependant été o... |
Family in the Age of COVID‐19 | |
COVID-19 Airway Management Isolation Chamber | OBJECTIVE: During the coronavirus pandemic (COVID-19), health care workers are innovating patient care and safety measures. Unfortunately, many of these are not properly tested for efficacy. The objective of this study was to determine the efficacy of the novel COVID-19 Airway Management Isolation Chamber (CAMIC) to co... |
Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations | Summary As coronavirus disease 2019 (COVID-19) spreads across the world, the intensive care unit (ICU) community must prepare for the challenges associated with this pandemic. Streamlining of workflows for rapid diagnosis and isolation, clinical management, and infection prevention will matter not only to patients with... |
Endpoints used in phase III randomized controlled trials of treatment options for COVID-19 | |
Prevalence of Multi-Resistant Microorganisms and Antibiotic Stewardship among Hospitalized Patients Living in Residential Care Homes in Spain: A Cross-Sectional Study | Antimicrobial resistance is a growing global health problem. Patients living in care homes are a vulnerable high-risk population colonized by multidrug-resistant organisms (MDRO). We identified a case series of 116 residents of care homes from a cohort of 540 consecutive patients admitted to the internal medicine servi... |
The role of lipid rafts in cell entry of human metapneumovirus | Human metapneumovirus (hMPV) is a crucial pathogen in children. A cell entry is the first step for infection. Our previous study indicated that there was an endocytosis pathway for hMPV cell entry. Lipid raft is a specific structure at the cell surface and it has been demonstrated to play an important role in endocytos... |
4 Cell Entry of Enveloped Viruses | Abstract Enveloped viruses penetrate their cell targets following the merging of their membrane with that of the cell. This fusion process is catalyzed by one or several viral glycoproteins incorporated on the membrane of the virus. These envelope glycoproteins (EnvGP) evolved in order to combine two features. First, t... |
Antigenic relationship of the feline infectious peritonitis virus to coronaviruses of other species | Utilizing the direct and indirect fluorescent antibody procedure, the antigenic relationship of the feline infectious peritonitis virus (FIPV) to 7 other human and animal coronaviruses was studied. FIPV was found to be closely related to transmissible gastroenteritis virus (TGEV) of swine. Transmissible gastroenteritis... |
A major gene for host response to porcine reproductive and respiratory syndrome is not unfavorably associated with overall performance under nonchallenging conditions in commercial pig lines | A QTL for host response to porcine reproductive and respiratory syndrome (PRRS) was identified in a previous study. The SNP WUR10000125 (WUR) is used as a tag SNP for this QTL. The favorable (B) allele at this SNP is in low frequency in commercial populations, possibly because this allele is unfavorably associated with... |
COVID-19 lockdowns throughout the world | |
Novel Viral Vectored Vaccines for the Prevention of Influenza | Influenza represents a substantial global healthcare burden, with annual epidemics resulting in 3–5 million cases of severe illness with a significant associated mortality. In addition, the risk of a virulent and lethal influenza pandemic has generated widespread and warranted concern. Currently licensed influenza vacc... |
Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology | Human coronaviruses (hCoVs) can be divided into low pathogenic and highly pathogenic coronaviruses. The low pathogenic CoVs infect the upper respiratory tract and cause mild, cold-like respiratory illness. In contrast, highly pathogenic hCoVs such as severe acute respiratory syndrome CoV (SARS-CoV) and Middle East resp... |
The Cuyahoga Is Still Burning | |
Reorganizing a Medicine Residency Program in Response to the COVID-19 Pandemic in New York | The COVID-19 pandemic has been particularly severe in New York City, resulting in a rapid influx of patients into New York–Presbyterian Hospital/Columbia University Irving Medical Center. The challenges precipitated by this pandemic have required urgent changes to existing models of care. Internal medicine residents ar... |
The novel immunomodulatory biologic LMWF5A for pharmacological attenuation of the “cytokine storm” in COVID-19 patients: a hypothesis | BACKGROUND: A common complication of viral pulmonary infections, such as in the ongoing COVID-19 pandemic, is a phenomenon described as a “cytokine storm”. While poorly defined, this hyperinflammatory response results in diffuse alveolar damage. The low molecular weight fraction of commercial human serum albumin (LMWF5... |
Decisions under uncertainty: a computational framework for quantification of policies addressing infectious disease epidemics | Emerging infectious diseases continue to place a strain on the welfare of the population by decreasing the population’s general health and increasing the burden on public health infrastructure. This paper addresses these issues through the development of a computational framework for modeling and simulating infectious ... |
Safety of Plasma Infusions in Parkinson's Disease | BACKGROUND: Young plasma infusions have emerged as a potential treatment for neurodegenerative disease, and convalescent plasma therapy has been used safely in the management of viral pandemics. However, the effect of plasma therapy in Parkinson's disease (PD) is unknown. OBJECTIVES: The objective of this study was to ... |
Attractiveness of an Aggregation Pheromone Lure and Chicken Droppings to Adults and Larvae of Alphitobius diaperinus (Coleoptera: Tenebrionidae) | The chemical cues by which lesser mealworm, Alphitobius diaperinus (Panzer) (Coleoptera: Tenebrionidae) beetles find each other are still unknown. Laboratory two-choice pitfall bioassays were conducted to evaluate the attractiveness of synthetic aggregation pheromone lure to lesser mealworm adults and larvae. All compo... |
Unequally vulnerable: a food justice approach to racial disparities in COVID-19 cases | |
Targeting of proteins to the Golgi apparatus | The proteins that reside in the Golgi carry out functions associated with post-translational modifications, including glycosylation and proteolytic processing, membrane transport, recycling of endoplasmic reticulum proteins and maintenance of the structural organisation of the organelle itself. The latter includes Golg... |
Ultrasound-guided interventions during the COVID-19 pandemic – a new challenge | |
KILchip v1.0: A Novel Plasmodium falciparum Merozoite Protein Microarray to Facilitate Malaria Vaccine Candidate Prioritization | Passive transfer studies in humans clearly demonstrated the protective role of IgG antibodies against malaria. Identifying the precise parasite antigens that mediate immunity is essential for vaccine design, but has proved difficult. Completion of the Plasmodium falciparum genome revealed thousands of potential vaccine... |
A LAIR-1 insertion generates broadly reactive antibodies against malaria variant antigens | Plasmodium falciparum antigens expressed on the surface of infected erythrocytes are important targets of naturally acquired immunity against malaria, but their high number and variability provide the pathogen with a powerful means of escape from host antibodies(1–4). Although broadly reactive antibodies against these ... |
Embracing telemedicine into your otolaryngology practice amid the COVID-19 crisis: An invited commentary | |
Cross-neutralization of SARS coronavirus-specific antibodies against bat SARS-like coronaviruses | |
The 18th Rocky Mountain Virology Association Meeting | This autumn, approximately 100 scientists and students from the Rocky Mountain area along with invited speakers attended the 18th annual meeting of the Rocky Mountain Virology Association that was held at the Colorado State University Mountain Campus. The two-day gathering featured 31 talks and 33 posters all of which ... |
Early Detection of Emerging Zoonotic Diseases with Animal Morbidity and Mortality Monitoring | Diseases transmitted between animals and people have made up more than 50% of emerging infectious diseases in humans over the last 60 years and have continued to arise in recent months. Yet, public health and animal disease surveillance programs continue to operate independently. Here, we assessed whether recent emergi... |
Polysialic acid is a cellular receptor for human adenovirus 52 | Human adenovirus 52 (HAdV-52) is one of only three known HAdVs equipped with both a long and a short fiber protein. While the long fiber binds to the coxsackie and adenovirus receptor, the function of the short fiber in the virus life cycle is poorly understood. Here, we show, by glycan microarray analysis and cellular... |
Study of surveillance data for class B notifiable disease in China from 2005 to 2014 | Summary Background The surveillance of infection is very important for public health management and disease control. It has been 10 years since China implemented its new web-based infection surveillance system, which covers the largest population in the world. Methods In this study, time series data were collected for ... |
Management of infections in critically ill returning travellers in the intensive care unit—II: clinical syndromes and special considerations in immunocompromised patients | Summary This position paper is the second ESCMID Consensus Document on this subject and aims to provide intensivists, infectious disease specialists, and emergency physicians with a standardized approach to the management of serious travel-related infections in the intensive care unit (ICU) or the emergency department.... |
Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses | At least five arenaviruses cause viral haemorrhagic fevers in humans. Lassa virus, an Old World arenavirus, uses the cellular receptor α-dystroglycan to infect cells(1). Machupo, Guanarito, Junin and Sabia viruses are New World haemorrhagic fever viruses that do not use α-dystroglycan(2). Here we show a specific, high-... |
Erratum for Byukusenge et al., “Complete Genome Sequences of Four Bovine Coronavirus Isolates from Pennsylvania” | [This corrects the article DOI: 10.1128/genomeA.00467-18.]. |
Therapeutic Synergy Between Antibiotics and Pulmonary Toll-Like Receptor 5 Stimulation in Antibiotic-Sensitive or -Resistant Pneumonia | Bacterial infections of the respiratory tract constitute a major cause of death worldwide. Given the constant rise in bacterial resistance to antibiotics, treatment failure is increasingly frequent. In this context, innovative therapeutic strategies are urgently needed. Stimulation of innate immune cells in the respira... |
Comment on “Generalized pustular figurate erythema: A newly delineated severe cutaneous drug reaction linked with hydroxychloroquine”: report of a COVID‐19 patient with particular findings | |
Quantifying the transmission potential of pandemic influenza | Abstract This article reviews quantitative methods to estimate the basic reproduction number of pandemic influenza, a key threshold quantity to help determine the intensity of interventions required to control the disease. Although it is difficult to assess the transmission potential of a probable future pandemic, hist... |
A time-of–drug addition approach to target identification of antiviral compounds | Insight into the mode of action of newly discovered antiviral agents is now almost a prerequisite for clinical development. This protocol describes a method that provides information on the target of inhibitors of the human immunodeficiency virus (HIV); it can also be adapted to other viruses. The results from this exp... |
In silico analysis of the cyanobacterial lectin scytovirin: new insights into binding properties | Scytovirin is a lectin isolated from the cyanobacterium Scytonema varium that has shown activity against HIV, SARS coronavirus and Zaire Ebola virus. Its 95 amino acids are divided into two structural domains (SD), the first spanning amino acids 1–48 (SD1) and the second 49–95 (SD2). Interestingly, the domains are near... |
The traditional uses, chemical constituents and biological activities of Plantago major L. A review | Abstract Plantago major L. leaves have been used as a wound healing remedy for centuries in almost all parts of the world and in the treatment of a number of diseases apart from wound healing. These include diseases related to the skin, respiratory organs, digestive organs, reproduction, the circulation, against cancer... |
Pseudoscience in medicine: cautionary recommendations | INTRODUCTION: Certain real life applications of scientific and social science ideas that knowingly reject accumulated empirical biomedical evidence have been termed ‘pseudoscience,’ or empirical rejectionism. An uncritical acceptance of empiricism, or even of evidence-based medicine, however, can also be problematic. O... |
A Primary Mediastinal Large B-Cell Lymphoma Patient With COVID-19 Infection After Intensive Immunochemotherapy: A Case Report | Background: The outbreak of coronavirus disease 2019 (COVID-19) had become a global public health event. Lymphoma patients need to be distinguished from the general population because of their deficient immune status and intensive anti-tumor treatment. The impacts of cancer subtypes and treatment on COVID-19 infection ... |
Does pandemic justify the use of Hydroxychloroquine for treatment and prevention of COVID‐19 in India? | The Indian Council of Medical Research (ICMR), recommended the use of hydroxychloroquine (HCQ) as a prophylactic against COVID‐19 among health care workers and asymptomatic contacts of laboratory confirmed cases of COVID. This is widely criticised as a hastily taken step with political inclination and minimal evidence ... |
Evaluation of safety, efficacy, tolerability, and treatment-related outcomes of type I interferons for Human coronaviruses (HCoVs) infection in clinical practice: An updated critical systematic review and meta-analysis | BACKGROUND: There is no vaccine or specific antiviral treatment for HCoVs infection. The use of type I interferons for coronavirus is still under great debate in clinical practice. MATERIALS AND METHODS: A literature search of all relevant studies published on PubMed, Cochrane library, Web of Science database, Science ... |
Coronaviridae and SARS-associated Coronavirus Strain HSR1 | During the recent severe acute respiratory (SARS) outbreak, the etiologic agent was identified as a new coronavirus (CoV). We have isolated a SARS-associated CoV (SARS-CoV) strain by injecting Vero cells with a sputum specimen from an Italian patient affected by a severe pneumonia; the patient traveled from Vietnam to ... |
MERS-CoV Antibody Responses 1 Year after Symptom Onset, South Korea, 2015 | We investigated the kinetics of the Middle East respiratory syndrome coronavirus (MERS-CoV) neutralizing and spike protein antibody titers over the course of 1 year in 11 patients who were confirmed by reverse transcription PCR to have been infected during the outbreak in South Korea in 2015. Robust antibody responses ... |
New Variant of Porcine Epidemic Diarrhea Virus, United States, 2014 | |
Risk Perception and COVID-19 | The ongoing COVID-19 pandemic is shaking the foundations of public health governance all over the world. Researchers are challenged by informing and supporting authorities on acquired knowledge and practical implications. This Editorial applies established theories of risk perception research to COVID-19 pandemic, and ... |
Reverse Genetics of SARS-Related Coronavirus Using Vaccinia Virus-Based Recombination | Severe acute respiratory syndrome (SARS) is a zoonotic disease caused by SARS-related coronavirus (SARS-CoV) that emerged in 2002 to become a global health concern. Although the original outbreak was controlled by classical public health measures, there is a real risk that another SARS-CoV could re-emerge from its natu... |
Clinical Characteristics of Critically Ill Patients Co-infected with SARS-CoV-2 and the Influenza Virus in Wuhan, China | OBJECTIVE: To delineate the clinical characteristics of critically ill COVID-19 patients co-infected with influenza. METHODS: In this study, we included adult patients with laboratory-confirmed COVID-19 form Tongji Hospital (Wuhan, China), with or without influenza, and compared their clinical characteristics. RESULTS:... |
Metabolomic Profiling of Infants With Recurrent Wheezing After Bronchiolitis | BACKGROUND: Bronchiolitis is associated with a greater risk of developing recurrent wheezing, but with currently available tools, it is impossible to know which infants with bronchiolitis will develop this condition. This preliminary prospective study aimed to assess whether urine metabolomic analysis can be used to id... |
Guillain-Barre Syndrome in a Patient With Evidence of Recent SARS-CoV-2 Infection | |
Burnout and PTSD in the COVID-19 Pandemic: Intersection, Impact and Interventions | Summary sentence Individual physicians and hospital administration should take proactive steps to minimize the compounding effects of high baseline burnout and the acute stressors of the COVID-19 pandemic in order to promote wellness among health-care providers. |
Cardiac drugs and outcome in COVID-19: Reply | |
Guide pour le suivi respiratoire des patients ayant présenté une pneumonie à SARS-CoV-2.Propositions de prise en charge élaborées par la Société de Pneumologie de Langue Française. Version du 10 mai 2020 | Résumé La Société de Pneumologie de Langue Française propose un guide pour le suivi respiratoire des patients ayant présenté une pneumonie à SARS-CoV-2 à partir des données connues des précédentes épidémies, des lésions aiguës constatées chez ces patients et d’opinions d’experts. Ce guide propose une conduite à tenir s... |
Protection afforded by respirators when performing endotracheal intubation using a direct laryngoscope, GlideScope®, and i-gel® device: A randomized trial | Emergency physicians are at risk of infection during invasive procedures, and wearing a respirator can reduce this risk. The aim of this study was to determine whether the protection afforded by a respirator during intubation is affected by the type of airway device used. In this randomized crossover study, 26 emergenc... |
Case Study 1 Ocean Park In the Face of Competition from Hong Kong Disneyland | In April 2006, Ocean Park, Hong Kong’s only home-grown theme park, launched a syndicated loan to raise HK$4.1 billion for a master plan to revamp the Park. The master plan represented the Park’s strategic response to the arrival of Hong Kong Disneyland, which had opened the previous year. Ocean Park had expected attend... |
Rapid Detection Strategies for the Global Threat of Zika Virus: Current State, New Hypotheses, and Limitations | The current scenario regarding the widespread Zika virus (ZIKV) has resulted in numerous diagnostic studies, specifically in South America and in locations where there is frequent entry of travelers returning from ZIKV-affected areas, including pregnant women with or without clinical symptoms of ZIKV infection. The Wor... |
Prevalence of Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels in Abu Dhabi Emirate, United Arab Emirates | High seroprevalence of Middle East respiratory syndrome corona virus (MERS-CoV) in dromedary camels has been previously reported in United Arab Emirates (UAE). However, the molecular detection of the virus has never been reported before in UAE. Of the 7,803 nasal swabs tested in the epidemiological survey, MERS-CoV nuc... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.