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Multiple mechanisms for HSV-1 induction of interferon α production by peripheral blood mononuclear cells | UV-inactivated, infectious, and other forms of herpes simplex virus 1 (HSV-1) induced interferon (IFN) production by different routes in myeloid origin mononuclear cells (MOMC) (consisting predominantly of monocytes). GM-CSF activated the MOMC (G-MOMC) to produce greater amounts of interferon while differentiation to D... |
Exposure to Influenza Virus Aerosols in the Hospital Setting: Is Routine Patient Care an Aerosol Generating Procedure? | |
Characterization of the ferret TRB locus guided by V, D, J, and C gene expression analysis | The domestic ferret, Mustela putorius furo, is an important mammalian animal model to study human respiratory infection. However, insufficient genomic annotation hampers detailed studies of ferret T cell responses. In this study, we analyzed the published T cell receptor beta (TRB) locus and performed high-throughput s... |
Effects of Xinjiaxiangruyin on the TLR7 pathway in influenza virus-infected lungs of mice housed in a hygrothermal environment | BACKGROUND: To investigate the effects and immunological mechanisms of the traditional Chinese medicine Xinjiaxiangruyin on controlling influenza virus (FM1 strain) infection in mice housed in a hygrothermal environment. METHODS: Mice were housed in normal and hygrothermal environments, and intranasally infected with i... |
Retargeting of Viruses to Generate Oncolytic Agents | Oncolytic virus therapy is based on the ability of viruses to effectively infect and kill tumor cells without destroying the normal tissues. While some viruses seem to have a natural preference for tumor cells, most viruses require the modification of their tropism to specifically enter and replicate in such cells. Thi... |
Mécanismes d’émergence virale et transmission interespèces : l’exemple des rétrovirus Foamy simiens chezl’Homme en Afrique Centrale | SUMMARY A large proportion of viral pathogens that have emerged during the last decades in humans are considered to have originated from various animal species. This is well exemplified by several recent epidemics such as those of Nipah, Severe Acute Respiratory Syndrome, Avian flu, Ebola, Monkeypox, and Hantaviruses. ... |
2015 ACVIM Forum Research Reports Program | |
Understanding and Modeling the Super-spreading Events of the Middle East Respiratory Syndrome Outbreak in Korea | |
Computational identification of self-inhibitory peptides from white spot syndrome virus envelope protein VP28 | Abstract Since effective chemotherapeutics or preventive measures are still unavailable, finding feasible approaches against white spot syndrome virus (WSSV) has always been the vital subject in shrimp farming field. Envelope proteins are the ideal targets for antiviral strategies development due to their indispensable... |
Molecular etiological profile of atypical bacterial pathogens, viruses and coinfections among infants and children with community acquired pneumonia admitted to a national hospital in Lima, Peru | OBJECTIVE: The main objective of this study was to detect the presence of 14 respiratory viruses and atypical bacteria (Mycoplasma pneumoniae, Chlamydia pneumoniae), via polymerase chain reaction in patients under 18 years old hospitalized due to community-acquired pneumonia (CAP) from Lima, Peru. RESULTS: Atypical pat... |
TAVR during the COVID19 Pandemic: The ACC/SCAI Consensus Statement | |
COVID-19: How to Use a Jet Nebulizer for Drug Administration in Ventilated Patients without Putting the Healthcare Workers at Risk | |
Sars-CoV-2: A clinical update - II | INTRODUCTION: A covid-19 pandemic decreed by WHO has raised greater awareness of it EPIDEMIOLOGY: The infection, reached the mark of 2,000,000 patients in 33 countries and caused the risk of the presence of comorbidities and advanced age TRANSMISSIBILITY: The transmissibility calculated so far is similar to the H1N1 ep... |
Multifacility Outbreak of Middle East Respiratory Syndrome in Taif, Saudi Arabia | Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) is a novel respiratory pathogen first reported in 2012. During September 2014–January 2015, an outbreak of 38 cases of MERS was reported from 4 healthcare facilities in Taif, Saudi Arabia; 21 of the 38 case-patients died. Clinical and public health records ... |
Novel Human Reovirus Isolated from Children with Acute Necrotizing Encephalopathy | For many encephalitis cases, the cause remains unidentified. After 2 children (from the same family) received a diagnosis of acute necrotizing encephalopathy at Centre Hospitalier Universitaire (Tours, France), we attempted to identify the etiologic agent. Because clinical samples from the 2 patients were negative for ... |
Mucosal immune responses induced by oral administration recombinant Bacillus subtilis expressing the COE antigen of PEDV in newborn piglets | Porcine epidemic diarrhea (PED) is a highly contagious disease in newborn piglets and causes substantial economic losses in the world. PED virus (PEDV) spreads by fecal–oral contact and can be prevented by oral immunization. Therefore, it is necessary to develop an effective oral vaccine against PEDV infection. Current... |
Pathologic Findings in Novel Influenza A (H1N1) Virus (“Swine Flu”) Infection: Contrasting Clinical Manifestations and Lung Pathology in Two Fatal Cases | Although novel influenza A (H1N1) virus infection has assumed pandemic proportions, there are few reports of the pathologic findings. Herein we describe the pathologic findings of novel influenza A (H1N1) infection based on findings in 2 autopsy cases. The first patient, a 36-year-old man, had flu-like symptoms; oselta... |
Use of Dual TaqMan Probes to Increase the Sensitivity of 1-Step Quantitative Reverse Transcription-PCR: Application to the Detection of SARS Coronavirus | |
Novel Coronavirus (COVID-19)-Associated Guillain–Barré Syndrome: Case Report | |
Doctor of Nursing Practice (DNP) Degree in the US: Reflecting, Readjusting, and Getting Back on Track | • Paper explores barriers to a universal DNP requirement for advanced practice nurses; • Includes cost analysis and perceptions of the DNP in today's professional environment; • Offers insights to help facilitate the implementation of a universal DNP standard. |
Pandemics, climate change, and disability related to SCI | |
Virus nuevos, viejos virus | |
Arterial thromboembolic complications in COVID‐19 in low‐risk patients despite prophylaxis | We present a case series of three patients with COVID-19 who developed arterial vascular complications, one who developed an acute CVA, one who developed popliteal artery occlusion and one who developed both during their hospital course. We present a case series of three patients admitted to Northwell Plainview Hospita... |
41 Mass Gatherings | Abstract A mass gathering is “any occasion, either organized or spontaneous, that attracts sufficient numbers of people to strain the planning and response resources of the community, city, or nation hosting the event.”2 Often the existing infrastructure (e.g., public health, health care, or emergency services) is inad... |
Why can't I visit? The ethics of visitation restrictions – lessons learned from SARS | Patients want, need and expect that their relatives will be able to visit them during inpatient admissions or accompany them during ambulatory visits. The sudden outbreak of severe acute respiratory syndrome (SARS), or a similar contagious pathogen, will restrict the number of people entering the hospital. The ethical ... |
7 Protecting blood safety | Publisher Summary This chapter is about components of volunteer blood donations that are each transfused as a single unit. A single donation of a pint of whole blood is virtually always separated by centrifugation into a unit of red blood cells and a unit of plasma; a unit of platelets or a unit of cryoprecipitated pla... |
Can moderate intensity aerobic exercise be an effective and valuable therapy in preventing and controlling the pandemic of COVID-19? | • Moderate intensity exercises modulate immunity. • Moderate intensity exercise may boost immunity thereby prevent incidences of COVID-19. • Moderate intensity exercises can also benefit those affected with diabetes and hypertension and other noncommunicable diseases. • Moderate intensity exercise can promote psycholog... |
Chapter One CISCEM 2014 Proceedings of the Second Conference on In situ and Correlative Electron Microscopy, Saarbrücken, Germany, October 14–15, 2014 | Abstract This chapter contains the extended abstracts of the second conference on in situ and correlative electron microscopy (CISCEM 2014), held October 14–15, 2014, in Saarbrücken, Germany. The conference was housed at the INM-Leibniz Institute for New Materials. The aim of the conference was to bring together an int... |
Highly conserved regions in Ebola virus RNA dependent RNA polymerase may be act as a universal novel peptide vaccine target: a computational approach | PURPOSE: Ebola virus (EBOV) is such kind of virus which is responsible for 23,825 cases and 9675 deaths worldwide only in 2014 and with an average diseases fatality rate between 25 % and 90 %. Although, medical technology has tried to handle the problems, there is no Food and Drug Administration (FDA)-approved therapeu... |
The ORF6, ORF8 and nucleocapsid proteins of SARS-CoV-2 inhibit type I interferon signaling pathway | The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel human coronavirus causing the pandemic of severe pneumonia (Coronavirus Disease 2019, COVID-19). SARS-CoV-2 is highly pathogenic in human, having posed immeasurable public health challenges to the world. Innate immune response is critical for t... |
The Australian response to the COVID-19 pandemic and diabetes – lessons learned | The COVID-19 pandemic has had a significant impact on the economy and health system of most countries in the world and this is also true of Australia. Australia has not seen the huge surge of COVID-19 positive cases and subsequent hospitalisations and deaths experienced in other parts of the world. However there have b... |
The Use of Ebola Convalescent Plasma to Treat Ebola Virus Disease in Resource-Constrained Settings: A Perspective From the Field | The clinical evaluation of convalescent plasma (CP) for the treatment of Ebola virus disease (EVD) in the current outbreak, predominantly affecting Guinea, Sierra Leone, and Liberia, was prioritized by the World Health Organization in September 2014. In each of these countries, nonrandomized comparative clinical trials... |
Retail Baitfish in Michigan Harbor Serious Fish Viral Pathogens | Indigenous small cyprinid fish species play an important role in Great Lakes ecosystems and also comprise the backbone of a multimillion‐dollar baitfish industry. Due to their widespread use in sport fisheries of the Laurentian Great Lakes, there are increasing concerns that baitfish may introduce or disseminate fish p... |
Practical Steps to Improve Air Flow in Long-Term Care Resident Rooms to Reduce COVID-19 Infection Risk | Abstract The potential for spread of COVID-19 infections in Skilled Nursing Facilities and other Long-Term Care sites poses new challenges for Nursing Home Administrators to protect patients and staff. It is anticipated that as Acute Care Hospitals reach capacity, Nursing Homes may retain COVID-19 infected residents lo... |
Understanding of COVID‐19 based on current evidence | Since December 2019, a series of unexplained pneumonia cases have been reported in Wuhan, China. On 12 January 2020, the World Health Organization (WHO) temporarily named this new virus as the 2019 novel coronavirus (2019‐nCoV). On 11 February 2020, the WHO officially named the disease caused by the 2019‐nCoV as corona... |
On Race and the Environment in the COVID-19 Pandemic | |
Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach | The sudden emergence of severe respiratory disease, caused by a novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), has recently become a public health emergency. Genome sequence analysis of SARS-CoV-2 revealed its close resemblance to the earlier reported SARS-CoV and Middle East respiratory syndrome cor... |
Contribution of autophagy to antiviral immunity | Although identified in the 1960’s, interest in autophagy has significantly increased in the past decade with notable research efforts oriented at understanding as to how this multi-protein complex operates and is regulated. Autophagy is commonly defined as a “self-eating” process evolved by eukaryotic cells to recycle ... |
Medication Errors | This section offers medication error-related news briefs as of July 1, 2020 The U S Food and Drug Administration (FDA) has issued a medical product safety alert warning consumers against taking the anthelmintic drug ivermectin intended for animals in an effort to prevent or cure coronavirus disease-2019 (COVID-19) The ... |
The simulation-CT: Radiotherapy’s useful tool in the race against COVID-19 pandemic. A serendipity approach | |
Novel ACE2-IgG1 fusions with improved activity against SARS-CoV2 | SARS-CoV2, the etiologic agent of COVID-19, uses ACE2 as a cell entry receptor. Soluble ACE2 has been shown to have neutralizing antiviral activity but has a short half-life and no active transport mechanism from the circulation into the alveolar spaces of the lung. To overcome this, we constructed an ACE2-human IgG1 f... |
COVID-19 and allergen immunotherapy: theoretical benefits invite to adjustments in practice recommendations | |
Chapter One Supramolecular Architecture of the Coronavirus Particle | Abstract Coronavirus particles serve three fundamentally important functions in infection. The virion provides the means to deliver the viral genome across the plasma membrane of a host cell. The virion is also a means of escape for newly synthesized genomes. Lastly, the virion is a durable vessel that protects the gen... |
Natural History of COVID-19 and Current Knowledge on Treatment Therapeutic Options | Despite intense research there is currently no effective vaccine available against the new severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in the later 2019 and responsible for the COVID-19 pandemic. This infectious and communicable disease has become one of the major public health challenges in th... |
State-of-the-art methods for studying air distributions in commercial airliner cabins | Abstract Air distributions in commercial airliner cabins are crucial for creating a thermally comfortable and healthy cabin environment. This paper reviews the methods used in predicting, designing, and analyzing air distributions in the cabins, among which experimental measurements and numerical simulations are the tw... |
Introduction: changing cultures of speed | This chapter outlines the widespread acceptance of speed as a positive aspect of urban transport during the 20th century, along with a growing recognition in recent decades that speed may not provide the advantages that have long been assumed. In 21st century urban planning, no longer are higher speeds always seen as t... |
The effects of the Spanish COVID-19 lockdown on people, their pets and the human-animal bond | The purpose of this study was to investigate the effects of the Spanish confinement for the control of the COVID-19 pandemic on the behavior of pet cats and dogs, and the support that pets provided to their owners. We found that the quality of life owners was strongly influenced by the lifestyle and emotional effects o... |
Complete Genome Sequence of Transmissible Gastroenteritis Coronavirus PUR46-MAD Clone and Evolution of the Purdue Virus Cluster | The complete sequence (28580 nt) of the PUR46-MAD clone of the Purdue cluster of transmissible gastroenteritis coronavirus (TGEV) has been determined and compared with members of this cluster and other coronaviruses. The computing distances among their S gene sequences resulted in the grouping of these coronaviruses in... |
‘And breathe…’? The sociology of health and illness in COVID‐19 time | |
Bacillus Calmette Guérin (BCG) vaccination use in the fight against COVID-19 – what’s old is new again? | |
Clinical Outcomes and Prognosis of Patients with HIV and SARS‐CoV‐2 Co‐infection | Dear Editor, I read with interest the review, “Living with HIV in the time of COVID‐19: a glimpse of hope” by Adadi et al. published in the Journal of Medical Virology. However, I believe that the conclusions made within this article should be taken with caution as the outcomes of patients co‐infected with HIV and SARS... |
New Chimeric Porcine Coronavirus in Swine Feces, Germany, 2012 | |
Immunological Control of Viral Infections in Bats and the Emergence of Viruses Highly Pathogenic to Humans | Bats are reservoir hosts of many important viruses that cause substantial disease in humans, including coronaviruses, filoviruses, lyssaviruses, and henipaviruses. Other than the lyssaviruses, they do not appear to cause disease in the reservoir bats, thus an explanation for the dichotomous outcomes of infections of hu... |
Chapter eleven Social, Cultural and Ethical Issues in the Traumatic Stress Field | Publisher Summary This chapter describes how the impact of psychological trauma differs depending upon the social and cultural context and the social and cultural resources available to individuals, families and communities. Disadvantaged persons and communities such as those experiencing poverty, stigma and discrimina... |
Recent expansion and adaptive evolution of the carcinoembryonic antigen family in bats of the Yangochiroptera subgroup | BACKGROUND: Expansions of gene families are predictive for ongoing genetic adaptation to environmental cues. We describe such an expansion of the carcinoembryonic antigen (CEA) gene family in certain bat families. Members of the CEA family in humans and mice are exploited as cellular receptors by a number of pathogens,... |
Hydroxychloroquine in SLE: old drug, new perspectives | Antimalarial agents have long been used in the treatment of autoimmune diseases, despite uncertainty regarding the exact mechanisms underlying their various effects. Growing evidence that these drugs offer protection from major infections could stimulate more research into these mechanisms, with possible implications f... |
Availability of Telemedicine Services Across Hospitals in the United States in 2018: A Cross-sectional Study | |
Outcomes of 3,737 COVID-19 patients treated with hydroxychloroquine/azithromycin and other regimens in Marseille, France: A retrospective analysis | BACKGROUND: In our institute in Marseille, France, we initiated early and massive screening for coronavirus disease 2019 (COVID-19). Hospitalization and early treatment with hydroxychloroquine and azithromycin (HCQ-AZ) was proposed for the positive cases. METHODS: We retrospectively report the clinical management of 3,... |
Organization of the outdoor blood donation drives amid novel coronavirus pandemic and national lockdown: An experience from a tertiary care oncology institution in India | Abstract The conduct of blood donation drives became difficult amid novel coronavirus disease pandemic and national lockdown. Despite no restriction for the outdoor blood donation drives, voluntary blood donor organizations (VBDOs) and individual donors became apprehensive regarding the possible risk of spread of the i... |
COVID‐19, Globalization, De‐globalization and the Slime Mold's Lessons For Us All | The world is struggling with the COVID‐19 pandemic on a backdrop of conflicting globalization and de‐globalization forces. A study of biology reveals that nature has been contending with such general issues for billions of years and has come up with broad strategies for their resolution. Copy and paste! |
COVID-19 Pulmonary and Olfactory Dysfunctions: Is the Chemokine CXCL10 the Common Denominator? | COVID-19 is an ongoing viral pandemic that emerged from East Asia and quickly spread to the rest of the world SARS-CoV-2 is the virus causing COVID-19 Acute respiratory distress syndrome (ARDS) is definitely one of the main clinically relevant consequences in patients with COVID-19 Starting from the earliest reports of... |
The impact of the COVID-19 pandemic on emergency department visits and patient safety in the United States | BACKGROUND: COVID-19 pandemic effects are still being elucidated. Stay-at-home orders and social distancing compounded with COVID-19 concerns have caused significant disruptions in daily life. One notable effect of these variables may be a change in the number of emergency department (ED) visits. This study aims to inv... |
Rhinopharyngites et otites récidivantes : situations à risque, conduite à tenir | Summary Rhinopharyngitis is a common disease in the pediatric population. Acute otitis media is the most frequent complication. Eustachian tube obstruction is responsible for underaeration of the middle-car. Congestion of the respiratory mucosa and adenoid hypertropy result in persistent middle ear effusion and recurre... |
Neutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain III | The Zika virus (ZIKV), a flavivirus transmitted by Aedes mosquitoes, has emerged as a global public health concern. Pre-existing cross-reactive antibodies against other flaviviruses could modulate immune responses to ZIKV infection by antibody-dependent enhancement, highlighting the importance of understanding the immu... |
Clinical evidence based review and recommendations of aerosol generating medical procedures in otolaryngology – head and neck surgery during the COVID-19 pandemic | BACKGROUND: Aerosol generating medical procedures (AGMPs) present risks to health care workers (HCW) due to airborne transmission of pathogens. During the COVID-19 pandemic, it is essential for HCWs to recognize which procedures are potentially aerosolizing so that appropriate infection prevention precautions can be ta... |
Epidemiological characteristics and spatial−temporal analysis of COVID-19 in Shandong Province, China | The pandemic of coronavirus disease 2019 (COVID-19) has posed serious challenges. It is vitally important to further clarify the epidemiological characteristics of the COVID-19 outbreak for future study and prevention and control measures. Epidemiological characteristics and spatial−temporal analysis were performed bas... |
Makeshift face shield for healthcare professionals during the COVID‐19 pandemic | |
Corona virus (Covid-19) – ITS implications in pediatric orthopedic care | The recent spread of severe acute respiratory syndrome corona virus 2 (SARS-CoV2) and its associated corona virus disease has gripped the entire international community and has caused widespread public health concerns due to unavailability of treatment to this deadly disease. The COVID -19 has affected healthcare worke... |
Endocytic Pathway of Feline Coronavirus for Cell Entry: Differences in Serotype-Dependent Viral Entry Pathway | Feline coronavirus (FCoV) is a pathogen causing a lethal infectious disease in cats, feline infectious peritonitis. It has two serotypes (type I FCoV and type II FCoV). According to our previous study, type I FCoV infection is inhibited by compounds inducing intracellular cholesterol accumulation, whereas type II FCoV ... |
Patient characteristics infected with Middle East respiratory syndrome coronavirus infection in a tertiary hospital | BACKGROUND: In April 2014, a surge in cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection was seen in Jeddah, Saudi Arabia. The aim of this study is to describe the demographic and clinical features, laboratory and radiological findings of MERS-CoV patients identified during this outbreak in a si... |
Vulnerable Immigrant Populations in the New York Metropolitan Area and COVID-19: Lessons Learned in the Epicenter of the Crisis | The epicenter of the COVID-19 crisis since March 17, 2020—the New York metropolitan area—is home to some of the largest Latino immigrant communities in the nation. These communities have long faced barriers to health care access, challenges due to immigration status, and financial and labor instability. The COVID-19 pa... |
Low Serum 25-Hydroxyvitamin D Level and Risk of Upper Respiratory Tract Infection in Children and Adolescents | Background. Vitamin D may be important for immune function. Studies to date have shown an inconsistent association between vitamin D and infection with respiratory viruses. The purpose of this study was to determine if serum 25-hydroxyvitamin D (25(OH)D) was associated with laboratory-confirmed viral respiratory tract ... |
First Confirmed Case of Middle East Respiratory Syndrome Coronavirus Infection in the Kingdom of Bahrain: In a Saudi Gentleman after Cardiac Bypass Surgery | Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is well known to cause severe respiratory infection and was first reported in the Kingdom of Saudi Arabia in 2012. We report here the first confirmed MERS-CoV infection in the Kingdom of Bahrain in a Saudi gentleman who was admitted electively for coronary bypass ... |
Serological Evidence of Influenza A Viruses in Frugivorous Bats from Africa | Bats are likely natural hosts for a range of zoonotic viruses such as Marburg, Ebola, Rabies, as well as for various Corona- and Paramyxoviruses. In 2009/10, researchers discovered RNA of two novel influenza virus subtypes – H17N10 and H18N11 – in Central and South American fruit bats. The identification of bats as pos... |
Staggered release policies for COVID-19 control: Costs and benefits of relaxing restrictions by age and risk | Lockdown and social distancing restrictions have been widely used as part of policy efforts aimed at controlling the ongoing COVID-19 pandemic. Since these restrictions have a negative impact on the economy, there exists a strong incentive to relax these policies while protecting public health. Using a modified SEIR ep... |
eBay Foundation increases commitment to COVID‐19 relief | |
Possibilities, Intentions and Threats: Dual Use in the Life Sciences Reconsidered | Due to the terrorist attacks of 9/11 and the anthrax letters of a few weeks later, the concept of dual use has spread widely in the life sciences during the past decade. This article is aimed at a clarification of the dual use concept and its scope of application for the life sciences. Such a clarification would greatl... |
The emerging influenza virus threat: status and new prospects for its therapy and control | Influenza A viruses (IAVs) are zoonotic pathogens that cause yearly outbreaks with high rates of morbidity and fatality. The virus continuously acquires point mutations while circulating in several hosts, ranging from aquatic birds to mammals, including humans. The wide range of hosts provides influenza A viruses great... |
Rhinovirus infections: induction and modulation of airways inflammation in asthma | There is renewed interest in the role of respiratory virus infections in the pathogenesis of asthma and in the development of exacerbations in pre‐existing disease. This is due to the availability of new molecular and experimental tools. Circumstantial evidence points towards a potentially causative role as well as to ... |
Heart Block in Patients with Coronavirus disease 19: A case series of 3 Patients infected with SARS-COV-2. | |
Preparation and characterization of an attenuated porcine epidemic diarrhea virus strain by serial passaging | Porcine epidemic diarrhea virus (PEDV) is prevalent in most parts of the world. Owing to its antigenic variation, prevention of the diseases caused by this virus is difficult. In this study, two PEDV isolates with similar growth kinetics were successfully propagated in Vero cells. Complete genome sequence analysis show... |
Currently available intravenous immunoglobulin contains antibodies reacting against severe acute respiratory syndrome coronavirus 2 antigens | AIM: There is a critical need for effective therapies that are immediately available to control the spread of COVID-19 disease. MATERIAL & METHODS: Gamunex(®)-C and Flebogamma(®) DIF (Grifols) intravenous immunoglobulin (IVIG) products were tested using ELISA techniques for antibodies against several antigens of human ... |
Effect of pollutant source location on air pollutant dispersion around a high-rise building | Abstract This article investigates the dispersion of airborne pollutants emitted from different locations near a high-rise building. A Computational Fluid Dynamics (CFD) model for simulating the wind flow field and the pollutant dispersion was developed and validated by wind tunnel data. Then the spreading of the pollu... |
SIR HELMET (Safety In Radiology HEalthcare Localised Metrological EnviromenT): a low-cost negative-pressure isolation barrier for shielding MRI frontline workers from COVID-19 exposure | • Low cost reusable acrylic and silicone rubber barrier shield design. • Localised negative pressure environment simulating isolation rooms. • Does not affect MRI image quality even on the most sensitive sequences. • Additional personal protective equipment for frontline healthcare professionals. |
The application of DNA nucleotide footprint plotting in coronavirus | Direct visualization of the key features of coronavirus genomes can lead to a better understanding of this virus as well as a method to distinguish this type of virus from others. The DNA nucleotide footprint plotter is a tool that makes it possible for straightforward visualization of the characteristics of viral geno... |
Suggested new breakpoints of anti-MERS-CoV antibody ELISA titers: performance analysis of serologic tests | To provide optimal cut-off values of anti-Middle East respiratory syndrome coronavirus (MERS-CoV) serologic tests, we evaluated performance of ELISA IgG, ELISA IgA, IFA IgM, and IFA IgG using 138 serum samples of 49 MERS-CoV-infected patients and 219 serum samples of 219 rRT-PCR-negative MERS-CoV-exposed healthcare per... |
Running field experiments using Facebook split test | Business researchers use experimental methods extensively due to their high internal validity. However, controlled laboratory and crowdsourcing settings often introduce issues of artificiality, data contamination, and low managerial relevance of the dependent variables. Field experiments can overcome these issues but a... |
Managing disasters amid COVID-19 pandemic: Approaches of response to flood disasters | Abstract The world faces difficulties to manage disasters while making efforts of slowing the spread of COVID-19. The paper aims at proposing policies and approaches to manage dual disasters of flooding and COVID-19. It reviews on-going efforts of organizations in the humanitarian assistance, water and sanitation, disa... |
La presencia de cardiopatía agrava el pronóstico de los pacientes con COVID-19 | |
Les phases de sortie de la crise du COVID-19 | |
Resuming work gradually in the context of COVID‐19: experience from a tertiary dermatology department in China | |
Bloodstream infections in critically ill patients with COVID‐19 | BACKGROUND: Little is known about the incidence and risk of intensive care unit (ICU)‐acquired bloodstream infections (BSI) in critically ill patients with coronavirus disease 2019 (COVID‐19). MATERIAL AND METHODS: This retrospective, single‐centre study was conducted in Northern Italy. The primary study objectives wer... |
2019 Novel-coronavirus: Cardiovascular Insights about Risk Factors, Myocardial Injury, Therapy and Clinical Implications | From December 31th, 2019, a novel highly pathogenic coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide, reaching at present the dimension of a pandemic. In addition to damaging the lungs, SARS-CoV-2 may also damage the heart and this is corroborated by the evidence that card... |
De l’utilité des animaux domestiques pour la recherche en immunologie | SUMMARY Domestic animals can be complementary to experimental mice for studying certain aspects of immunology. For example, they can offer surgical access to the physiology of lymphoid organs in vivo, in utero immunisation for studies of immune system ontogeny, and the pathogenesis of infections in their natural target... |
Drivers for emerging issues in animal and plant health | The history of agriculture includes many animal and plant disease events that have had major consequences for the sector, as well as for humans. At the same time, human activities beyond agriculture have often driven the emergence of diseases. The more that humans expand the footprint of the global population, encroach... |
Managing recalls and withdrawals of blood components | Abstract Donor centers are issuing a growing number of recalls and market withdrawals to hospital transfusion services about blood components. More than 1 in 2,000 units were recalled in the late 1990s in the United States. The most common reason for these notices from donor centers is postdonation donor information. M... |
Air conditioning systems: Testing air cleaning devices | Is it possible to test air cleaning or disinfection devices used in air conditioning systems? We look at a potential testing system, and see if it is possible to compare different devices and determine optimum operating conditions. |
2 Core Competencies to Create Effective Protection Programs | Abstract To accomplish the goals of successful management practice, what’s important has to be determined. This chapter looks at the evolution of security as a management activity. The growth of services, products, and systems is provided. Most important security threats are presented. |
Frequency and clinical relevance of human bocavirus infection in acute exacerbations of chronic obstructive pulmonary disease | OBJECTIVE: Human bocavirus (HBoV) is a recently discovered parvovirus associated with acute respiratory tract infections in children. The objective of the present study was to determine the frequency and clinical relevance of HBoV infection in adult patients with acute exacerbation of chronic obstructive pulmonary dise... |
Staphylococcus aureus Complex in the Straw-Colored Fruit Bat (Eidolon helvum) in Nigeria | Bats are economically important animals and serve as food sources in some African regions. They can be colonized with the Staphylococcus aureus complex, which includes Staphylococcus schweitzeri and Staphylococcus argenteus. Fecal carriage of S. aureus complex in the straw-colored fruit bat (Eidolon helvum) has been de... |
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