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PMID:20657 | Labeling immunoelectrophoresis: a general method for increasing the sensitivity of rocket immunoelectrophoresis with 125I-labeled anti-antibodies. | In a new procedure, rocket immunoelectrophoresis is performed at pH 8.7 with rabbit antibodies and 5% polyethyleneglycol 6000 in the agarose gel. After the pH in the gel has been changed to 5 the nonprecipitated immunoglobulins are electrophorsed out of the gel simultaneously with the electrophoresis of 125I-labeled sw... | Labeling immunoelectrophoresis: a general method for increasing the sensitivity of rocket immunoelectrophoresis with 125I-labeled anti-antibodies. In a new procedure, rocket immunoelectrophoresis is performed at pH 8.7 with rabbit antibodies and 5% polyethyleneglycol 6000 in the agarose gel. After the pH in the gel has... | [
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PMID:20658 | [Therapy of childhood schizophrenia]. | Due to the multifacet genesis and variability of clinical phenomenology, the therapy of childhood schizophrenia must be multidimensional. Formerly applied techniques like electroshock- and insulin-therapy are now replaced by pharmaco-therapy, primarily with phenothiazines, butyrophenones and chlorprothixens. The dosage... | [Therapy of childhood schizophrenia]. Due to the multifacet genesis and variability of clinical phenomenology, the therapy of childhood schizophrenia must be multidimensional. Formerly applied techniques like electroshock- and insulin-therapy are now replaced by pharmaco-therapy, primarily with phenothiazines, butyroph... | [
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PMID:20661 | Metallic contamination of food during preparation and storage: development of methods and some preliminary results. | A chemical procedure for studying trace metals leached from metallic cooking utensils and preserving cans used in the preparation and storage of food has been developed. The method consists in the destruction of the major part of organic matter with HNO3-vapour followed by a complete mineralization of residues with sma... | Metallic contamination of food during preparation and storage: development of methods and some preliminary results. A chemical procedure for studying trace metals leached from metallic cooking utensils and preserving cans used in the preparation and storage of food has been developed. The method consists in the destruc... | [
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PMID:20663 | Folate conjugase: two separate activities in human jejunum. | Previous perfusion studies of the human jejunum suggested that conjugated folate is hydrolyzed on the mucosal surface. The techniques of cell fractionation and DEAE and gel chromatography led to the identification of two separate folate conjugase activities in human jejunal mucosa: one membrane-bound and concentrated i... | Folate conjugase: two separate activities in human jejunum. Previous perfusion studies of the human jejunum suggested that conjugated folate is hydrolyzed on the mucosal surface. The techniques of cell fractionation and DEAE and gel chromatography led to the identification of two separate folate conjugase activities in... | [
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PMID:20664 | Memory formation: evidence for a specific neurochemical system in the amygdala. | beta-Adrenergic antagonists injected into the amygdala complex of rats trained in a passive avoidance task produced time-dependent and dose-dependent decreases in retention of the task. In addition, the effects observed with beta-adrenergic antagonists were both stereospecific and reversed by norepinephrine. The result... | Memory formation: evidence for a specific neurochemical system in the amygdala. beta-Adrenergic antagonists injected into the amygdala complex of rats trained in a passive avoidance task produced time-dependent and dose-dependent decreases in retention of the task. In addition, the effects observed with beta-adrenergic... | [
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PMID:20665 | Biogenic amine synthesis defect in dihydropteridine reductase deficiency. | In the enzymatic hydroxylation of aromatic amino acids, tetrahydrobiopterin is the essential cofactor. Regeneration of tetrahydrobiopterin requires dihydropteridine reductase, without which there should be a deficiency of hydroxylated amino acids and their products, biogenic amines. Assay of biopsied brain cortex of a ... | Biogenic amine synthesis defect in dihydropteridine reductase deficiency. In the enzymatic hydroxylation of aromatic amino acids, tetrahydrobiopterin is the essential cofactor. Regeneration of tetrahydrobiopterin requires dihydropteridine reductase, without which there should be a deficiency of hydroxylated amino acids... | [
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PMID:20666 | [Measurement of plasma renin activity, blood volume and exchangeable sodium: an aid in the orientation of treatment of essential arterial hypertension]. | 95 patients with essential uncomplicated hypertension were mostly submitted to measurement of plasma renin activity, plasma volume and exchangeable sodium. According to the results of the plasma renin activity, we noted variations in blood volume and exchangeable sodium in order to determine the best possible treatment... | [Measurement of plasma renin activity, blood volume and exchangeable sodium: an aid in the orientation of treatment of essential arterial hypertension]. 95 patients with essential uncomplicated hypertension were mostly submitted to measurement of plasma renin activity, plasma volume and exchangeable sodium. According t... | [
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PMID:20667 | [Persistant danger of smallpox and necessity of continuing mandatory smallpox vaccination in France]. | The WHO stated a short time ago that the total eradication of smallpox would occur shortly. This announcement has been contradicted by an epidemic of smallpox in Somaila which in spite of the energetic measures taken, remained in the capital from August 1976 to January 1977 then extended to 10 regions out of 16 with fr... | [Persistant danger of smallpox and necessity of continuing mandatory smallpox vaccination in France]. The WHO stated a short time ago that the total eradication of smallpox would occur shortly. This announcement has been contradicted by an epidemic of smallpox in Somaila which in spite of the energetic measures taken, ... | [
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PMID:20671 | Premedication with flunitrazepam in gastro-intestinal endoscopy. | Administration of 2 mg flunitrazepam (Rohypnol; Roche) to patients before gastro-intestinal endoscopy caused significantly less anxiety and achieved significantly greater sedation than diazepam (Vallium; Roche). No differences were found between any of the trial groups with respect to ease of intubation, tolerance of t... | Premedication with flunitrazepam in gastro-intestinal endoscopy. Administration of 2 mg flunitrazepam (Rohypnol; Roche) to patients before gastro-intestinal endoscopy caused significantly less anxiety and achieved significantly greater sedation than diazepam (Vallium; Roche). No differences were found between any of th... | [
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PMID:20672 | Pediatric plastic surgery. | Each section of this article has been discussed in severe brevity. Potential pitfalls have been expanded in an attempt to be helpful to the general surgeon who attends patients with these clinical problems. Making the relatives aware of a potential complication in its broadest sense is the responsibility of the surgeon... | Pediatric plastic surgery. Each section of this article has been discussed in severe brevity. Potential pitfalls have been expanded in an attempt to be helpful to the general surgeon who attends patients with these clinical problems. Making the relatives aware of a potential complication in its broadest sense is the re... | [
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PMID:20673 | The effect of (+) --cyanidanol on lysosomal enzymes of I-cell fibroblasts. | (+)--Cyanidanol, a water-soluble flavonoid, when added to cultured skin fibroblasts of a patient with I-cell disease raised the intracellular concentration of beta-galactosidase but did not affect the distribution of arylsulfatase. A, alpha-mannosidase or beta-glucuronidase. The elevated accumulation of 35SO4 by I-cell... | The effect of (+) --cyanidanol on lysosomal enzymes of I-cell fibroblasts. (+)--Cyanidanol, a water-soluble flavonoid, when added to cultured skin fibroblasts of a patient with I-cell disease raised the intracellular concentration of beta-galactosidase but did not affect the distribution of arylsulfatase. A, alpha-mann... | [
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PMID:20674 | Structure-activity relationships of some selected beta-adrenergic blocking agents--oxidation with N-bromosuccinimide. | A relationship between in vitro rate of oxidation by N-bromosuccinimide (NBS) and the pharmacologic activity (pA2) of different beta-adrenergic blockers for different blocking agent-tissue combinations has been studied. The rates of oxidation of the alcoholic group in the drugs by NBS, as well as their molecular confor... | Structure-activity relationships of some selected beta-adrenergic blocking agents--oxidation with N-bromosuccinimide. A relationship between in vitro rate of oxidation by N-bromosuccinimide (NBS) and the pharmacologic activity (pA2) of different beta-adrenergic blockers for different blocking agent-tissue combinations ... | [
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PMID:20678 | Fine structural localization of phosphatases in cilia and basal bodies of Tetrahymena pyriformis. | Cytochemical localization of ATPase activities in cilia and basal bodies of Tetrahymena pyriformis revealed a number of possible sites of ATPases. In basal bodies, reaction product was localized on the periphery of basal body microtubules, in the core of the B-microtubules, on the dense basal body core, and on the basa... | Fine structural localization of phosphatases in cilia and basal bodies of Tetrahymena pyriformis. Cytochemical localization of ATPase activities in cilia and basal bodies of Tetrahymena pyriformis revealed a number of possible sites of ATPases. In basal bodies, reaction product was localized on the periphery of basal b... | [
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PMID:20683 | Treatment of detrusor hyperreflexia in multiple sclerosis: a double-blind, crossover clinical trial comparing methantheline bromide (Banthine), flavoxate chloride (Urispas) and meladrazine tartrate (Lisidonil). | 34 patients suffering from detrusor hyperreflexia due to multiple sclerosis entered the trial and 32 patients accomplished. The patients received each drug for a period of 14 days. The patients made records of relevant symptoms, urgency and urge incontinence and compared the treatment periods according to these symptom... | Treatment of detrusor hyperreflexia in multiple sclerosis: a double-blind, crossover clinical trial comparing methantheline bromide (Banthine), flavoxate chloride (Urispas) and meladrazine tartrate (Lisidonil). 34 patients suffering from detrusor hyperreflexia due to multiple sclerosis entered the trial and 32 patients... | [
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PMID:20684 | [Urologic symptoms in the abdominal muscle deficiency syndrome (author's transl)]. | The abdominal muscle deficiency syndrome ("prune belly syndrome"(, a symptom triad of aplasia of the abdominal wall musculature, malformations of the urinary tract, and cryptorchism, is described from the urologist's point of view, citing nine cases. With modern diagnostic procedures the early detection of the correct ... | [Urologic symptoms in the abdominal muscle deficiency syndrome (author's transl)]. The abdominal muscle deficiency syndrome ("prune belly syndrome"(, a symptom triad of aplasia of the abdominal wall musculature, malformations of the urinary tract, and cryptorchism, is described from the urologist's point of view, citin... | [
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PMID:20686 | Platelet adhesion to foreign surfaces under controlled conditions of whole blood flow: human vs rabbit, dog, calf, sheep, pig, macaque, and baboon. | Our results reveal significant differences between mammalian species with respect to platelet adhesion to foreign surfaces exposed to heparinized, flowing blood. In particular, we have demonstrated the following: 1) At a surface shear rate characteristic of shear rates in mammalian arteries, human platelet adhesion (an... | Platelet adhesion to foreign surfaces under controlled conditions of whole blood flow: human vs rabbit, dog, calf, sheep, pig, macaque, and baboon. Our results reveal significant differences between mammalian species with respect to platelet adhesion to foreign surfaces exposed to heparinized, flowing blood. In particu... | [
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PMID:20693 | [Characteristics of the ecology of the eastern equine encephalomyelitis virus in the Republic of Cuba]. | Virologic and serological surveys of wild vertebrates carried out in various provinces of Cuba demonstrated definitely that birds were the main hosts of eastern equine encephalomyelitis (EEE) virus in this territory. Fifteen strains of this virus were isolated from 8 species of birds belonging to 5 orders. Isolation of... | [Characteristics of the ecology of the eastern equine encephalomyelitis virus in the Republic of Cuba]. Virologic and serological surveys of wild vertebrates carried out in various provinces of Cuba demonstrated definitely that birds were the main hosts of eastern equine encephalomyelitis (EEE) virus in this territory.... | [
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PMID:20692 | [Inhibiting action of glycomacropeptide on stomach secretion induced by various humoral stimulants]. | Tests staged on dogs demonstrated the action of GMP to differ depending upon the nature of the gastric secretion stimulant actually used. The inhibition of the gastric juice secretion occurring against the background of multiple introduction of histamine or gastrin tetrapeptide amide was quite spectacular: the secretio... | [Inhibiting action of glycomacropeptide on stomach secretion induced by various humoral stimulants]. Tests staged on dogs demonstrated the action of GMP to differ depending upon the nature of the gastric secretion stimulant actually used. The inhibition of the gastric juice secretion occurring against the background of... | [
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PMID:20699 | [The acid-alkaline equilibrium of the organism and the age (author's transl)]. | In 90 patients (three aging groups: from 20 to 29 years, from 60 to 69 years, from 80 to 89 years) with a physiologic aged status are investigated parameters of acid-alkaline equilibrium. There are no essential aging changes of the blood pH and other parameters, which characterize the acid-alkaline balance of the organ... | [The acid-alkaline equilibrium of the organism and the age (author's transl)]. In 90 patients (three aging groups: from 20 to 29 years, from 60 to 69 years, from 80 to 89 years) with a physiologic aged status are investigated parameters of acid-alkaline equilibrium. There are no essential aging changes of the blood pH ... | [
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PMID:20700 | [The water-electrolyte-change and the age (author's transl)]. | In 403 healthy probands between 20 and 103 years old the ionogram of the erythrocytes and of the plasma was analysed. In the one part of the test persons (75 probands) also the water spaces of the organism was examinated. It was established, that the electrolyte composing of the blood is changing with increasing age. I... | [The water-electrolyte-change and the age (author's transl)]. In 403 healthy probands between 20 and 103 years old the ionogram of the erythrocytes and of the plasma was analysed. In the one part of the test persons (75 probands) also the water spaces of the organism was examinated. It was established, that the electro... | [
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PMID:20703 | [The proximal gastric vagotomy in the treatment of uncomplicated duodenal ulcer (author's transl)]. | Of 97 patients, who had a PGV since July 1971, 86 were checked intraoperatively on completeness of vagotomy with various methods, including Kongo-red-staining, pH-electrode and Burge-test. On theoretical grounds, the Burge-test combined with pH-measurement seems the most reliable procedure. In 14 cases an incomplete Va... | [The proximal gastric vagotomy in the treatment of uncomplicated duodenal ulcer (author's transl)]. Of 97 patients, who had a PGV since July 1971, 86 were checked intraoperatively on completeness of vagotomy with various methods, including Kongo-red-staining, pH-electrode and Burge-test. On theoretical grounds, the Bur... | [
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PMID:20708 | The assay of protein-bound nitrite in meat products. | An improved procedure for the determination of protein-bound nitrite (PBN) in meat products, based on Mirna's method, is described. The results obtained with this modification are significantly higher, and have a lower variation coefficient, than those provided by the old procedure. This is demonstrated by comparison o... | The assay of protein-bound nitrite in meat products. An improved procedure for the determination of protein-bound nitrite (PBN) in meat products, based on Mirna's method, is described. The results obtained with this modification are significantly higher, and have a lower variation coefficient, than those provided by th... | [
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PMID:20709 | [Studies on the growth of the width in seminiferous tubules of eutopic and congenitally dystopic testes in children and adolescents]. | The average diameter of the seminiferous tubules is to be regarded as a criterion for the estimation of the morphological value of testicles. By means of 89 autoptically got preparations of regularly descended testicles the breadth-growth of the tubules depending on age in children was judged. Of 55 untreated congenita... | [Studies on the growth of the width in seminiferous tubules of eutopic and congenitally dystopic testes in children and adolescents]. The average diameter of the seminiferous tubules is to be regarded as a criterion for the estimation of the morphological value of testicles. By means of 89 autoptically got preparations... | [
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PMID:20710 | [Length-growth of seminiferous tubules of untreated and as surgically displaced, congenitallydystopic testes in children and adolescents]. | The total length of the seminiferous tubules of congenital dystopic testicles was calculated from bioptical preparations. 55 untreated testicles, 79 unilaterally and 78 bilaterally operatively displaced testicles as well as 78 contralaterally eutopic testicles were evaluated. During the whole prepuberal phase of life i... | [Length-growth of seminiferous tubules of untreated and as surgically displaced, congenitallydystopic testes in children and adolescents]. The total length of the seminiferous tubules of congenital dystopic testicles was calculated from bioptical preparations. 55 untreated testicles, 79 unilaterally and 78 bilaterally ... | [
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PMID:20705 | Gamma-radiolysis of aqueous solution of histidine. | The dependence of Gi(-M) values of histidine on the concentration of irradiated 10(-4) - 10(-1)M solutions, pH and the presence of O2, N2O and sec-butyl alcohol was investigated. In oxygen-free medium the maximum radiation sensitivity of histidine was found at pH 5--8; in oxygenated solutions it was shifted to the 6--1... | Gamma-radiolysis of aqueous solution of histidine. The dependence of Gi(-M) values of histidine on the concentration of irradiated 10(-4) - 10(-1)M solutions, pH and the presence of O2, N2O and sec-butyl alcohol was investigated. In oxygen-free medium the maximum radiation sensitivity of histidine was found at pH 5--8;... | [
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PMID:20706 | On the influence of aromatic residues on the interaction of copper (II) with small peptides containing aromatic amino acids: ESR and optical studies. | The complexation behaviour of Cu(II) with di- and tripeptides containing the aromatic amino acids phenylalanine or typtophan has been investigated at different pH-values and compared with results obtained with di- and triglycine. The results obtained by means of ESR and optical absorption spectroscopy show an influence... | On the influence of aromatic residues on the interaction of copper (II) with small peptides containing aromatic amino acids: ESR and optical studies. The complexation behaviour of Cu(II) with di- and tripeptides containing the aromatic amino acids phenylalanine or typtophan has been investigated at different pH-values ... | [
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PMID:20719 | Dehydrogenase activity and microbial population in a red sandy soil amended and unamended with incubation. | Incubation of single bulk sample of freshly collected red sandy soil in trays showed immediate response to added nutrients both in dehydrogenase activity and bacterial and fungal populations. The prevailing acidic pH might have been responsible for the observed response of fungi as well. Actinomycetes population did no... | Dehydrogenase activity and microbial population in a red sandy soil amended and unamended with incubation. Incubation of single bulk sample of freshly collected red sandy soil in trays showed immediate response to added nutrients both in dehydrogenase activity and bacterial and fungal populations. The prevailing acidic... | [
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PMID:20720 | [Purification of protease from staphylococcus aureus (author's transl)]. | 380 (80%) of 475 Staphylococcus aureus cultures isolated from humans, cattle and dogs were proteolytically active either on casein or gelatin or both (table 1). Protease-activity could also be demonstrated in experimental body-cavities of rabbits (fig. 1). The enzyme-activity was estimated with azocasein. Protease from... | [Purification of protease from staphylococcus aureus (author's transl)]. 380 (80%) of 475 Staphylococcus aureus cultures isolated from humans, cattle and dogs were proteolytically active either on casein or gelatin or both (table 1). Protease-activity could also be demonstrated in experimental body-cavities of rabbits ... | [
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PMID:20721 | [On the determination of chlorine with a polarographic probe. 1st communication: Examination of the physical properties of the new instrument (author's transl)]. | A new chlorine measuring device for the field use in the water plant praxis was tested. The portable instrument supplied with a selectively permeable membrane works basing on the polarographic principle and shall allow an easy and accurate measurement of the "disinfectingpower" of a water chlorination. In the 1st note ... | [On the determination of chlorine with a polarographic probe. 1st communication: Examination of the physical properties of the new instrument (author's transl)]. A new chlorine measuring device for the field use in the water plant praxis was tested. The portable instrument supplied with a selectively permeable membrane... | [
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PMID:20723 | Local hyperalimentation of experimental granulation tissue. | The effect of local hyperalimentation on developing granulation tissue was studied in rats. Cylindrical hollow viscose cellulose sponge implants were used subcutaneously as an inductive matrix fro the growth of granulation tissue. In the first, control group the implants were kept untouched while the second, "sham" gro... | Local hyperalimentation of experimental granulation tissue. The effect of local hyperalimentation on developing granulation tissue was studied in rats. Cylindrical hollow viscose cellulose sponge implants were used subcutaneously as an inductive matrix fro the growth of granulation tissue. In the first, control group t... | [
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PMID:20727 | Diazepam and flunitrazepam as induction agents for cardiac surgical operations. | Diazepam and flunitrazepam were compared in equipotent doses as induction agents for premedicated patients having cardiac surgery. Both drugs caused a significant fall in arterial blood pressure, a rise in Paco2 and a fall in Pao2. There was no significant difference between the two drugs in onset time of anaesthesia, ... | Diazepam and flunitrazepam as induction agents for cardiac surgical operations. Diazepam and flunitrazepam were compared in equipotent doses as induction agents for premedicated patients having cardiac surgery. Both drugs caused a significant fall in arterial blood pressure, a rise in Paco2 and a fall in Pao2. There wa... | [
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PMID:20728 | The effects of PaCO2 reduction on regional cerebral blood flow in the acute phase of brain injury. | In 26 unconscious patients with brain injuries, regional cerebral blood flow (rCBF) was measured with a 16-channel Cerebrograph before and after acute reduction of PaCO2. The intra-arterial 133xenon washout technique was used, and CBF was calculated regionally as initial slope index or stochastic flow. The CO2 reactivi... | The effects of PaCO2 reduction on regional cerebral blood flow in the acute phase of brain injury. In 26 unconscious patients with brain injuries, regional cerebral blood flow (rCBF) was measured with a 16-channel Cerebrograph before and after acute reduction of PaCO2. The intra-arterial 133xenon washout technique was ... | [
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PMID:20729 | Parkinsonian tremor: a neuropharmacological study. | In the Parkinsonian syndrome tremor is the symptom which still eludes pharmacological therapy. The authors report the results of nine cases of Parkinsonian tremor in which agonist and antagonist drugs acting on the receptors were employed. These were dopaminergics, acetylcholinergics, serotoninergics, histaminics, and ... | Parkinsonian tremor: a neuropharmacological study. In the Parkinsonian syndrome tremor is the symptom which still eludes pharmacological therapy. The authors report the results of nine cases of Parkinsonian tremor in which agonist and antagonist drugs acting on the receptors were employed. These were dopaminergics, ace... | [
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PMID:20736 | Evidence of decarboxylation of lysine by mammalian ornithine decarboxylase. | In enzymic preparations from mouse kidney stimulated with the anabolic steroid Durabolin (nandrolone phenpropionate) lysine and ornithine were shown to inhibit the decarboxylation of each other competitively. The Michaelis constants for the decarboxylations were approximately equal to the inhibition constants of the tw... | Evidence of decarboxylation of lysine by mammalian ornithine decarboxylase. In enzymic preparations from mouse kidney stimulated with the anabolic steroid Durabolin (nandrolone phenpropionate) lysine and ornithine were shown to inhibit the decarboxylation of each other competitively. The Michaelis constants for the dec... | [
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PMID:20741 | New amino acid derivatives formed by alkaline treatment of proteins. | Intense heat treatment of proteins at high pH favors formation of transient, reactive intermediates derived from serine and cystine. The postulated dehydroalanine intermediate reacts further with the epsilon-amino groups side chains and sulfhydryl groups of cysteine residues to form derivatives of lysinoalanine and lan... | New amino acid derivatives formed by alkaline treatment of proteins. Intense heat treatment of proteins at high pH favors formation of transient, reactive intermediates derived from serine and cystine. The postulated dehydroalanine intermediate reacts further with the epsilon-amino groups side chains and sulfhydryl gro... | [
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PMID:20743 | 35S-Sulfide incorporation during alkaline treatment of keratin and its relation to lanthionine formation. | Cattle hair exposed to solutions of 35S-sulfide ions at pH 12.5, hydrolyzed with acid, and analyzed for amino acids with simultaneous measurement of the radioactivity of the eluate from the analytical column showed 87 percent of the radioactivity incorporated in the hair in three amino acids: cysteic acid, lanthionine,... | 35S-Sulfide incorporation during alkaline treatment of keratin and its relation to lanthionine formation. Cattle hair exposed to solutions of 35S-sulfide ions at pH 12.5, hydrolyzed with acid, and analyzed for amino acids with simultaneous measurement of the radioactivity of the eluate from the analytical column showed... | [
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PMID:20738 | Treatment of the "syndrome of doubles". | An account of the response to biological treatment of 20 patients with the syndrome of doubles (syndrome of Capgras, syndrome of Frégoli, syndrome of Intermetamorphosis, syndrome of subjective doubles) is presented. Our observations indicate that: a) the syndrome of doubles may respond to various biological treatment m... | Treatment of the "syndrome of doubles". An account of the response to biological treatment of 20 patients with the syndrome of doubles (syndrome of Capgras, syndrome of Frégoli, syndrome of Intermetamorphosis, syndrome of subjective doubles) is presented. Our observations indicate that: a) the syndrome of doubles may r... | [
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PMID:20744 | Lysinoalanine formation in wool after treatments with some phosphate salts. | Treatment of wool with solutions of sodium tripolyphosphate, potassium tetrapyrophosphate, and sodium phosphate results in the formation of lysinoalanine, the amount of which increases from the first to the last reagent. As this may be due to the different pH, solutions of the three salts of the same pH were also tried... | Lysinoalanine formation in wool after treatments with some phosphate salts. Treatment of wool with solutions of sodium tripolyphosphate, potassium tetrapyrophosphate, and sodium phosphate results in the formation of lysinoalanine, the amount of which increases from the first to the last reagent. As this may be due to t... | [
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PMID:20745 | The formation and cleavage of lysinoalanine crosslinks. | Treatment of lysinoalanine (LAL) with methyl iodide at pH-values above 8 leads to cleavage to dehydroalanine (DHA) and Nepsilon-di- or/and trimethyllysine, as was shown by ultraviolet spectra and amino acid analysis. This reaction is due to methylation of the crosslinking NH group of LAL to the quaternary ammonium comp... | The formation and cleavage of lysinoalanine crosslinks. Treatment of lysinoalanine (LAL) with methyl iodide at pH-values above 8 leads to cleavage to dehydroalanine (DHA) and Nepsilon-di- or/and trimethyllysine, as was shown by ultraviolet spectra and amino acid analysis. This reaction is due to methylation of the cros... | [
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PMID:20746 | On the specific cleavage of cysteine containing peptides and proteins. | Addition of cysteine to the double bonds of polydehydroalanine and copolymers of dehydroalanine (DHA) and methylcysteine, alanine, leucine or gamma- methyl-L-glutamate is accompanied by increased solubility and decreased molecular weight. This result is due to a peptide bond cleavage caused by formation of a thiazolidi... | On the specific cleavage of cysteine containing peptides and proteins. Addition of cysteine to the double bonds of polydehydroalanine and copolymers of dehydroalanine (DHA) and methylcysteine, alanine, leucine or gamma- methyl-L-glutamate is accompanied by increased solubility and decreased molecular weight. This resul... | [
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PMID:20747 | Reactions of proteins with dehydroalanines. | Reactions of proteins with dehydroalanine or derivatives of dehydroalanine were studied as models for protein crosslinking. Treatment of casein, bovine serum albumin, lysozyme, wool or polylysine with acetamido- and phenylacetamido acrylic acid methyl esters at pH 9-10 converted varying amounts of lysine to lysinoalani... | Reactions of proteins with dehydroalanines. Reactions of proteins with dehydroalanine or derivatives of dehydroalanine were studied as models for protein crosslinking. Treatment of casein, bovine serum albumin, lysozyme, wool or polylysine with acetamido- and phenylacetamido acrylic acid methyl esters at pH 9-10 conver... | [
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PMID:20748 | The formation, isolation and importance of isopeptides in heated proteins. | The separation and resolution of the isopeptides Nepsilon (gamma-L-glutamyl)-L-lysine and Nepsilon (beta-aspertyl)-L-lysine, formed in heated proteins, has been successfully achieved. The method demands a well characterised ion-exchange column and the use of pH 3.40 lithium citrate buffer (O.2N Li+). Due to variations ... | The formation, isolation and importance of isopeptides in heated proteins. The separation and resolution of the isopeptides Nepsilon (gamma-L-glutamyl)-L-lysine and Nepsilon (beta-aspertyl)-L-lysine, formed in heated proteins, has been successfully achieved. The method demands a well characterised ion-exchange column a... | [
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PMID:20749 | Cross-linking of protein by peroxidase. | The reaction products of peroxidase, a hydrogen donor and hydrogen peroxide decreased the amount of lysine recovered from proteins after acid hydrolysis. Oxidation of peroxidase treated proteins with performic acid prior to hydrolysis formed alpha-amino adipic acid indicating that the peroxidase or the quinones formed ... | Cross-linking of protein by peroxidase. The reaction products of peroxidase, a hydrogen donor and hydrogen peroxide decreased the amount of lysine recovered from proteins after acid hydrolysis. Oxidation of peroxidase treated proteins with performic acid prior to hydrolysis formed alpha-amino adipic acid indicating tha... | [
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PMID:20750 | Biological effects of alkali-treated protein and lysinoalanine: an overview. | The renal alterations induced by alkali-treated protein and lysinoalanine are reviewed and their biological implications discussed. Alkali-treated proteins and lysinoalanine, an unusual amino acid formed in proteins during alkali treatment, have been shown to produce a renal alteration characterized by nuclear and cyto... | Biological effects of alkali-treated protein and lysinoalanine: an overview. The renal alterations induced by alkali-treated protein and lysinoalanine are reviewed and their biological implications discussed. Alkali-treated proteins and lysinoalanine, an unusual amino acid formed in proteins during alkali treatment, ha... | [
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PMID:20752 | Some chemical and nutritional properties of feather protein isolates containing varying half-cystine levels. | Feather (keratinous) protein isolates containing 2.8 and 7.2% half-cystine were prepared. Solubility of the former increased to 100% between pH 6 and 12, whereas, that of the latter reached only 2.5% at pH 12. Tests showed that mixtures of sodium dodecyl sulfate and 2-mercaptoethanol were needed to completely solubiliz... | Some chemical and nutritional properties of feather protein isolates containing varying half-cystine levels. Feather (keratinous) protein isolates containing 2.8 and 7.2% half-cystine were prepared. Solubility of the former increased to 100% between pH 6 and 12, whereas, that of the latter reached only 2.5% at pH 12. T... | [
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PMID:20754 | Protected proteins in ruminant nutrition. In vitro evaluation of casein derivatives. | Chemical treatment of proteins in feeds can, by crosslinking protein chains or other chemical effects, decrease their solubility and microbial degradation in the rumen. A need exists to modify proteins systematically under well-defined conditions with inexpensive reagents and to evaluate the treated products nutritiona... | Protected proteins in ruminant nutrition. In vitro evaluation of casein derivatives. Chemical treatment of proteins in feeds can, by crosslinking protein chains or other chemical effects, decrease their solubility and microbial degradation in the rumen. A need exists to modify proteins systematically under well-defined... | [
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PMID:20758 | Inhibitory effect of mercaptoamino acids on lysino-alanine formation during alkali treatment of proteins. | Alkali treatment of food proteins converts some amino acid residues to the unnatural amino acid lysinoalanine which has been found to cause kidney damage when fed to rats. Formation of lysinoalanine was essentially prevented when isolates of soy protein and casein were exposed to alkali in the presence of thio-alamino ... | Inhibitory effect of mercaptoamino acids on lysino-alanine formation during alkali treatment of proteins. Alkali treatment of food proteins converts some amino acid residues to the unnatural amino acid lysinoalanine which has been found to cause kidney damage when fed to rats. Formation of lysinoalanine was essentially... | [
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PMID:20761 | Structural proteins of infectious bovine rhinotracheitis virus. | Infectious bovine rhinotracheitis (IBR) virus grown in bovine embryo kidney cell cultures was concentrated and purified in Ficoll density gradients. The polypeptide composition of the virus was studied by polyacrylamide gel electrophoresis. The mature virion was found to contain 18 structural proteins with molecular we... | Structural proteins of infectious bovine rhinotracheitis virus. Infectious bovine rhinotracheitis (IBR) virus grown in bovine embryo kidney cell cultures was concentrated and purified in Ficoll density gradients. The polypeptide composition of the virus was studied by polyacrylamide gel electrophoresis. The mature viri... | [
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PMID:20762 | Investigation on the mechanisms of the failure of human influenza virus to replicate in chick embryo cell cultures. | Thirteen strains of human influenza virus producing in chick embryo cell (CEC) cultures either virions with low infectivity or no virions were studied. In CEC, most of the strains induced synthesis of viral RNA, polypeptides, and ribonucleoprotein and produced functionaly active haemagglutinin, neuraminidase and virion... | Investigation on the mechanisms of the failure of human influenza virus to replicate in chick embryo cell cultures. Thirteen strains of human influenza virus producing in chick embryo cell (CEC) cultures either virions with low infectivity or no virions were studied. In CEC, most of the strains induced synthesis of vir... | [
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PMID:20763 | Suppressive effect of Newcastle disease virus on the primary and secondary immune responses of hamsters. | The effect of Newcastle disease virus (NDV) on the formation of 19 S haemolytic plaque-forming cells (HPFC) in the secondary immune response and on the formation of 7 S HPFC in both primary and secondary immune responses of hamsters to sheep red blood cells (SRBC) was studied. The 19 S and the 7 S HPFC in the spleens o... | Suppressive effect of Newcastle disease virus on the primary and secondary immune responses of hamsters. The effect of Newcastle disease virus (NDV) on the formation of 19 S haemolytic plaque-forming cells (HPFC) in the secondary immune response and on the formation of 7 S HPFC in both primary and secondary immune resp... | [
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PMID:20764 | Concentration and purification of tick-borne encephalitis virus grown in suspensions of chick embryo cells. | Tick-borne encephalitis (TBE) virus grown in suspensions of chick embryo cells was precipitated by various concentrations of polyethylene glycol (PEG) 6000. Quantitative recovery was obtained at PEG concentrations of 5% and higher. As precipitation of contaminating non-viral protein increases with increasing PEG concen... | Concentration and purification of tick-borne encephalitis virus grown in suspensions of chick embryo cells. Tick-borne encephalitis (TBE) virus grown in suspensions of chick embryo cells was precipitated by various concentrations of polyethylene glycol (PEG) 6000. Quantitative recovery was obtained at PEG concentration... | [
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PMID:20765 | Characterization of tick-borne encephalitis virus and immunogenicity of its surface components in mice. | Tick-borne encephalitis (TBE) virus grown in chick embryo cells and purified by rate-zonal centrifugation was shown to have a density of 1.195 g/cm3 in sucrose density gradients. Under the conditions used, CsCl centrifugation caused disruption of the virus and less than 5% of input infectivity could be recovered from t... | Characterization of tick-borne encephalitis virus and immunogenicity of its surface components in mice. Tick-borne encephalitis (TBE) virus grown in chick embryo cells and purified by rate-zonal centrifugation was shown to have a density of 1.195 g/cm3 in sucrose density gradients. Under the conditions used, CsCl centr... | [
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PMID:20766 | Potentiation of langat virus infection by lead intoxication--influence on host defenses. | Pathogenesis was studied in mice with moderate levels of lead intoxication after Langat virus infection. Both lead chloride and lead nitrate increased mortality by 40--50%. This increase was associated with decreased in vivo interferon and neutralizing antibody synthesis. The increased mortality was associated with enh... | Potentiation of langat virus infection by lead intoxication--influence on host defenses. Pathogenesis was studied in mice with moderate levels of lead intoxication after Langat virus infection. Both lead chloride and lead nitrate increased mortality by 40--50%. This increase was associated with decreased in vivo interf... | [
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PMID:20767 | Non-infectious antigen for laboratory diagnosis of Japanese encephalitis. | Sucrose-acetone suckling mouse brain antigens of Na-kayama NIH, JaGAr-01 and Peking-1 strains of Japanese encephalitis (JE) virus treated with beta-propiolactone (BPL) retained their ability to specifically react in haemagglutination inhibition (HI) tests with antibody to JE virus, as demonstrated with convalescent ser... | Non-infectious antigen for laboratory diagnosis of Japanese encephalitis. Sucrose-acetone suckling mouse brain antigens of Na-kayama NIH, JaGAr-01 and Peking-1 strains of Japanese encephalitis (JE) virus treated with beta-propiolactone (BPL) retained their ability to specifically react in haemagglutination inhibition (... | [
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PMID:20768 | Measles antibodies in nasal secretions and sera of children with measles. | Measles antibodies were determined, in the course of measles, in sera and nasal secretions of 54 and 27 children, respectively. The examinations were performed on the 3rd or 4th day (1st period) and between the 10th and 14th day (2nd period) after onset of rash in both sera and nasal secretions and after 25 to 60 days ... | Measles antibodies in nasal secretions and sera of children with measles. Measles antibodies were determined, in the course of measles, in sera and nasal secretions of 54 and 27 children, respectively. The examinations were performed on the 3rd or 4th day (1st period) and between the 10th and 14th day (2nd period) afte... | [
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PMID:20769 | Comparison of interferon-inducing activities and antiviral effects of tobacco mosaic virus, tilorone and sodium nucleinate. | Endogenous interferon was produced in animals in response to the administration of tobacco mosaic virus (TMV), tilorone and sodium nucleinate. The relationship between interferon production and the kind of inducer and the route of its administration was studied. TMV was completely innocuous for Macaca rhesus monkeys an... | Comparison of interferon-inducing activities and antiviral effects of tobacco mosaic virus, tilorone and sodium nucleinate. Endogenous interferon was produced in animals in response to the administration of tobacco mosaic virus (TMV), tilorone and sodium nucleinate. The relationship between interferon production and th... | [
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PMID:20770 | Transmission of alfalfa mosaic virus through Nicandra physaloides seeds and its localization in embryo cotyledons. | Alfalfa mosaic virus (AMV) was found to be transmitted through seeds of Nicandra physaloids L. The average seed transmission rate of the AMV isolates T6, LMBG-4 and ST amounted to 23, 4 and 0 per cent, repectively. In the cytoplasm of parenchyma cells of embryo cotyledons of seeds from plants infected with the T6 isola... | Transmission of alfalfa mosaic virus through Nicandra physaloides seeds and its localization in embryo cotyledons. Alfalfa mosaic virus (AMV) was found to be transmitted through seeds of Nicandra physaloids L. The average seed transmission rate of the AMV isolates T6, LMBG-4 and ST amounted to 23, 4 and 0 per cent, rep... | [
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PMID:20771 | Simple method for preparation of immune sera to envelope and nucleocapsid antigens of Semliki Forest virus. | Immune sera to the envelope and nucleocapsid components of Zaisan 260 and R 16225 strains of Semliki Forest virus (SFV) were prepared with the use of disrupted, partially purified virus. | Simple method for preparation of immune sera to envelope and nucleocapsid antigens of Semliki Forest virus. Immune sera to the envelope and nucleocapsid components of Zaisan 260 and R 16225 strains of Semliki Forest virus (SFV) were prepared with the use of disrupted, partially purified virus. | [
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PMID:20773 | Chemical interactions between thiamin and tannic acid. II. Separation of products. | Bio Rex 70 column chromatography and high voltage paper electrophoresis were used to fractionate and define the reaction products of thiamin-tannic acid and thiamin-tea mixtures. Fractions separated indicated the presence of (a) thiamin-tannic acid adduct(s) and several modified forms of thiamin among the products. Usi... | Chemical interactions between thiamin and tannic acid. II. Separation of products. Bio Rex 70 column chromatography and high voltage paper electrophoresis were used to fractionate and define the reaction products of thiamin-tannic acid and thiamin-tea mixtures. Fractions separated indicated the presence of (a) thiamin-... | [
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PMID:20774 | Binding of zinc and iron to wheat bread, wheat bran, and their components. | Wholemeal wheat bread decreases the availability and intestinal absorption of divalent metals. To define this action further, binding of zinc in vitro to a wheat wholemeal bread (Tanok), dephytinized Tanok, and cellulose was determined at pH 5.0 to 7.5. Zinc binding by each was highly pH-dependent and reached a maximum... | Binding of zinc and iron to wheat bread, wheat bran, and their components. Wholemeal wheat bread decreases the availability and intestinal absorption of divalent metals. To define this action further, binding of zinc in vitro to a wheat wholemeal bread (Tanok), dephytinized Tanok, and cellulose was determined at pH 5.0... | [
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PMID:20776 | Ionic flux across canine duodenum. Movement of bicarbonate. | Effect of isosmotic biocarbonate-rich solutions on the Brunner's gland area were studied by means of proximal duodenal explants in eight anesthetized dogs. Volume gain occurred with all instillates and varied indirectly with the concentration of the bicarbonate in the instilled solutions. Net bicarbonate gain occurred ... | Ionic flux across canine duodenum. Movement of bicarbonate. Effect of isosmotic biocarbonate-rich solutions on the Brunner's gland area were studied by means of proximal duodenal explants in eight anesthetized dogs. Volume gain occurred with all instillates and varied indirectly with the concentration of the bicarbonat... | [
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PMID:20777 | Necrotizing vasculitis of the gallbladder and the appendix. Similarity in the morphology of rheumatoid arteritis and Polyarteritis nodosa. | Two patients with rheumatoid arthritis (RA) and polyarteritis nodosa (PN) presented with abdominal pain. Both revealed necrotizing vasculitis of the gallbladder and the appendix respectively. The controversial role of corticosteroids in the pathogenesis of rheumatoid arteritis, the rarity of rheumatoid arteritis of the... | Necrotizing vasculitis of the gallbladder and the appendix. Similarity in the morphology of rheumatoid arteritis and Polyarteritis nodosa. Two patients with rheumatoid arthritis (RA) and polyarteritis nodosa (PN) presented with abdominal pain. Both revealed necrotizing vasculitis of the gallbladder and the appendix res... | [
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PMID:20778 | The effect of ethanol and bile on electrolyte movement across canine proximal duodenal mucosa. | The existence of a gastric mucosal barrier, controlling H+ N+ flux has been well established. The disruption of this barrier by ethanol and bile has also been confirmed. This study was designed to investigate the effect of ethanol and bile on the duodenal mucosa, which, as we have shown, is similar to gastric mucosa in... | The effect of ethanol and bile on electrolyte movement across canine proximal duodenal mucosa. The existence of a gastric mucosal barrier, controlling H+ N+ flux has been well established. The disruption of this barrier by ethanol and bile has also been confirmed. This study was designed to investigate the effect of et... | [
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PMID:20781 | Sequential morphologic alterations in the bronchial epithelium of Syrian golden hamsters during N-nitrosomorpholine-induced pulmonary tumorigenesis. | N-nitrosomorpholine (NM)-induced pulmonary carcinogenesis was examined by light and electron microscopy in a 20-week serial sacrifice study using Syrian golden hamsters. First to be observed were a proliferation of endocrine APUD cells and a formation of lamellated inclusion bodies in the cytoplasm of Clara cells. Afte... | Sequential morphologic alterations in the bronchial epithelium of Syrian golden hamsters during N-nitrosomorpholine-induced pulmonary tumorigenesis. N-nitrosomorpholine (NM)-induced pulmonary carcinogenesis was examined by light and electron microscopy in a 20-week serial sacrifice study using Syrian golden hamsters. F... | [
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PMID:20783 | Blockade of myocardial slow inward current at low pH. | The effect of low pH on the slow cationic inward current was studied in isolated perfused embryonic chick ventricles (16-21 days old). In order to study the slow current, the fast Na+ current was inactivated by partial depolarization to about -40 mV by elevation of K+ (25 mM). Subsequent exposure of the tissue to catec... | Blockade of myocardial slow inward current at low pH. The effect of low pH on the slow cationic inward current was studied in isolated perfused embryonic chick ventricles (16-21 days old). In order to study the slow current, the fast Na+ current was inactivated by partial depolarization to about -40 mV by elevation of ... | [
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PMID:20785 | Rio Grande--a new phlebotomus fever group virus from south Texas. | Three strains of a new Phlebotomus fever group virus were isolated from pack rats (Neotoma micropus) collected in south Texas during 1973--1974; the name Rio Grande was proposed for this virus. The virus is pH 3.0 labile, sensitive to the action of sodium deoxycholate and heat (56 degrees C) labile. The results of a se... | Rio Grande--a new phlebotomus fever group virus from south Texas. Three strains of a new Phlebotomus fever group virus were isolated from pack rats (Neotoma micropus) collected in south Texas during 1973--1974; the name Rio Grande was proposed for this virus. The virus is pH 3.0 labile, sensitive to the action of sodiu... | [
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PMID:20788 | Multiple endocrine adenomatosis type IIB. Report of two cases and review of the literature. | The combination of bilateral medullary thyroid cancer, bilateral pheochromocytoma, Marfanoid body habitus with arachnodactyly, pectus excavatum, mucosal neuromas, and hyperplastic corneal nerves has become recognized as a definite entity, multiple endocrine adenomatosis (MEA) Type IIB. Two cases of MEA Type IIB are des... | Multiple endocrine adenomatosis type IIB. Report of two cases and review of the literature. The combination of bilateral medullary thyroid cancer, bilateral pheochromocytoma, Marfanoid body habitus with arachnodactyly, pectus excavatum, mucosal neuromas, and hyperplastic corneal nerves has become recognized as a defini... | [
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PMID:20790 | [Continuity of life situation and "successful" aging (author's transl)]. | The determinants of "successful" aging have been a main concern in social gerontological research. The Continuity Hypothesis suggests that there is a relationship between an older person's life satisfaction and the similarity of his social life situation in middle adulthood and in old age. The old person is the more li... | [Continuity of life situation and "successful" aging (author's transl)]. The determinants of "successful" aging have been a main concern in social gerontological research. The Continuity Hypothesis suggests that there is a relationship between an older person's life satisfaction and the similarity of his social life si... | [
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PMID:20791 | [Psychic help for aged people of day-care-centers by attending person-centered encounter groups (author's transl)]. | 45 old people (Average age 72 years) took part in 9 person-centered encounter groups together with younger people (Average age 32 years). Psychological changes of the old people were collected by questionaires and compared to a control group of 38 old people who subsequently took part in 4 encounter groups without youn... | [Psychic help for aged people of day-care-centers by attending person-centered encounter groups (author's transl)]. 45 old people (Average age 72 years) took part in 9 person-centered encounter groups together with younger people (Average age 32 years). Psychological changes of the old people were collected by question... | [
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PMID:20792 | [Poverty in old age (author's transl)]. | The legitimate claim on social assistance riveted in the Federal Legislation on Social Welfare and deduced from the welfare-state-postulate of the Constitution is only partially valid (obligatory assistance only). Applying this claim substantially is legally tied to discretionary decisions of the administration. Handli... | [Poverty in old age (author's transl)]. The legitimate claim on social assistance riveted in the Federal Legislation on Social Welfare and deduced from the welfare-state-postulate of the Constitution is only partially valid (obligatory assistance only). Applying this claim substantially is legally tied to discretionary... | [
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PMID:20793 | [Causes and outward forms of poverty in old age (author's transl)]. | In the Federal Rupublic nearly 20% of the elderly people live on the edge of below the property-line, which is well-marked by public assistance. In spite of legal claims 75% of the needy elderly do not explore all possible avenues. The ascertainment of this high percentage which had been never estimated exactly-about w... | [Causes and outward forms of poverty in old age (author's transl)]. In the Federal Rupublic nearly 20% of the elderly people live on the edge of below the property-line, which is well-marked by public assistance. In spite of legal claims 75% of the needy elderly do not explore all possible avenues. The ascertainment of... | [
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PMID:20794 | [Significance of environmental hygiene for aging individuals (author's transl)]. | Problems in the field of modern hygiene have changed in parallel with the current shift of morbidity and mortality in the direction of non-infections diseases such as vascular and circulatory disturbances and malignant tumors. As a consequence, hygienic care for the aged is becoming increasingly more important, and wit... | [Significance of environmental hygiene for aging individuals (author's transl)]. Problems in the field of modern hygiene have changed in parallel with the current shift of morbidity and mortality in the direction of non-infections diseases such as vascular and circulatory disturbances and malignant tumors. As a consequ... | [
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PMID:20795 | [Education: a theme in gerontology (author's transl)]. | The paper presents a review of the history of educational gerontology ("andragogy" or "gerontagogy") which has a special role within the field of gerontology. Whereas gerontological sciences such as biology, medicine, psychology, and sociology in (frequently interdisciplinary) approaches study the process of aging, edu... | [Education: a theme in gerontology (author's transl)]. The paper presents a review of the history of educational gerontology ("andragogy" or "gerontagogy") which has a special role within the field of gerontology. Whereas gerontological sciences such as biology, medicine, psychology, and sociology in (frequently interd... | [
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PMID:20796 | [Interrelationship of motivation and barriers in the learning process in old age (author's transl)]. | Started from the concept of lifelong learning it is discussed that the relation between motivation and barriers or obstructions has important influence on learning in old age. Even if differential view has been regarded, in general we may suppose that motivation will have a decreasing tendency and barriers an increasin... | [Interrelationship of motivation and barriers in the learning process in old age (author's transl)]. Started from the concept of lifelong learning it is discussed that the relation between motivation and barriers or obstructions has important influence on learning in old age. Even if differential view has been regarded... | [
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PMID:20797 | [Consistency and variability of intellectual and psychomotor abilities in aged people (author's transl)]. | Several methods of statistical analyses, featuring as well group specific changes and intra-individual changes, in an investigation of intelligence, psychomotor abilities of 121 aged men and women over a period of 7 years, lead to results that there are many different aspects of consistancy and change. An attempt is ma... | [Consistency and variability of intellectual and psychomotor abilities in aged people (author's transl)]. Several methods of statistical analyses, featuring as well group specific changes and intra-individual changes, in an investigation of intelligence, psychomotor abilities of 121 aged men and women over a period of ... | [
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PMID:20798 | [Evaluating programs for preparation to old age: some theoretical thoughts and a practical example (author's transl)]. | In the first part methodically satisfactory experimental designs for evaluating programs for preparation to old age on the basis of Cambell & Stanely (1963) are sketched including conditions which hinder the realization of the ideal notions. In the second part an experiment for comparing two preparatory courses to ... | [Evaluating programs for preparation to old age: some theoretical thoughts and a practical example (author's transl)]. In the first part methodically satisfactory experimental designs for evaluating programs for preparation to old age on the basis of Cambell & Stanely (1963) are sketched including conditions which ... | [
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PMID:20799 | [Academic learn in old age (author's transl)]. | To test the capacity of the elderly to sustain prolonged intellectual activity, 80 volunteers from 60 to 90 years of age received instruction in reading German, previously not studied by them. Special methods of instruction were employed to stimulate interest and self confidence. Independent tests after three and six m... | [Academic learn in old age (author's transl)]. To test the capacity of the elderly to sustain prolonged intellectual activity, 80 volunteers from 60 to 90 years of age received instruction in reading German, previously not studied by them. Special methods of instruction were employed to stimulate interest and self conf... | [
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PMID:20800 | [Age dependence of carbohydrate tolerance and insulin secretion (author's transl)]. | In 81 healthy male volunteers with normal blood pressure, normal body weight of different age (18-58 years) an intravenous glucose tolerance test with determination of blood sugar and serum insulin levels was done. Furthermore triglycerids and total cholesterol serum levels were measured. The investigations have shown:... | [Age dependence of carbohydrate tolerance and insulin secretion (author's transl)]. In 81 healthy male volunteers with normal blood pressure, normal body weight of different age (18-58 years) an intravenous glucose tolerance test with determination of blood sugar and serum insulin levels was done. Furthermore triglycer... | [
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PMID:20801 | [Manifest and latent folic acid deficiency in the aged (author's transl)]. | The serum folate level of 100 aged persons (after 70) was decreased (less than 4 ng/ml) in 41% of the cases (manifest deficiency of folic acid). In the group of aged persons having normal folate values, in 41% of the cases the clearance method proved a latent folic acid deficiency, being the 15 minute value after 15 ga... | [Manifest and latent folic acid deficiency in the aged (author's transl)]. The serum folate level of 100 aged persons (after 70) was decreased (less than 4 ng/ml) in 41% of the cases (manifest deficiency of folic acid). In the group of aged persons having normal folate values, in 41% of the cases the clearance method p... | [
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PMID:20802 | [Importance of space analysis of U-moment-vectors concerning ageing people and chronical heart and blood circulation diseases (author's transl)]. | U-vectors are a stabil component of electric activity of the heart repolarisation. The examinations of the space sizes and direction of the U-moment-vectors give an idea about the character of repolarisation of Purkinje's fibres and papillar muscles in old age and in chronical heart and blood circulation diseases. Path... | [Importance of space analysis of U-moment-vectors concerning ageing people and chronical heart and blood circulation diseases (author's transl)]. U-vectors are a stabil component of electric activity of the heart repolarisation. The examinations of the space sizes and direction of the U-moment-vectors give an idea abou... | [
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PMID:20803 | [Analysis of gait in hemiplegics (author's transl)]. | The gait of 31 hemiplegics is analyzed with a multiplecomponents force-plate. The healthy and paretic side differ in 5 of 7 parameters. The difference betwen the left and right side is bigger in the right hemiplegic, because in the left hemiplegic, the healthy side is more disturbed as in the right hemiplegic. That mak... | [Analysis of gait in hemiplegics (author's transl)]. The gait of 31 hemiplegics is analyzed with a multiplecomponents force-plate. The healthy and paretic side differ in 5 of 7 parameters. The difference betwen the left and right side is bigger in the right hemiplegic, because in the left hemiplegic, the healthy side i... | [
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PMID:20804 | [Geriatric aspects in operative treatment of intertrochanteric fractures (author's transl)]. | On the basis of published data and of 702 osteosyntheses carried out using the Pohl sliding hip screw, the authors come to the conclusion that the mortality rate in geriatric patients is not correlated to the method of osteosynthesis used. Of utmost importance are immediate operation and early mobilisation. The osteosy... | [Geriatric aspects in operative treatment of intertrochanteric fractures (author's transl)]. On the basis of published data and of 702 osteosyntheses carried out using the Pohl sliding hip screw, the authors come to the conclusion that the mortality rate in geriatric patients is not correlated to the method of osteosyn... | [
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PMID:20805 | [Morphological changes of the female urinary bladder in the elderly. Chronic infections of the urinary tract; the importance of their intensive treatment as preparatory measure for rehabilitation (author's transl)]. | The urinary bladder of the elderly is showing a reduced adaptability on account of morphological changes; it is therefore more prone to infections. The morphological changes consist in a reduction of muscle fibres and in an increase of collagen fibres and in elastosis, furthermore in a sklerosis of the intramural arter... | [Morphological changes of the female urinary bladder in the elderly. Chronic infections of the urinary tract; the importance of their intensive treatment as preparatory measure for rehabilitation (author's transl)]. The urinary bladder of the elderly is showing a reduced adaptability on account of morphological changes... | [
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PMID:20808 | [The pH-changes of the spinal fluid following bupivacaine (author's transl)]. | The ph-changes of cerebral spinal fluid were measured following subarachnoid injection of bupivacaine 0.5% with and without adrenaline (1:200,000) during the three hours after the start of anaesthesia. At the same time drug precipitation was not detected. The ph-changes however, were pronounced but not enough to cause ... | [The pH-changes of the spinal fluid following bupivacaine (author's transl)]. The ph-changes of cerebral spinal fluid were measured following subarachnoid injection of bupivacaine 0.5% with and without adrenaline (1:200,000) during the three hours after the start of anaesthesia. At the same time drug precipitation was ... | [
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PMID:20820 | Experimental cryptorchidism in adult male rats: histological and hormonal sequelae. | Mature male rats were rendered cryptorchid and followed for up to nine weeks during which serial blood specimens were obtained for multiple hormonal analyses; serial testicular samples were obtained as well. In contrast with control animals, cryptorchid rats showed transient rises in FSH which returned to normal at the... | Experimental cryptorchidism in adult male rats: histological and hormonal sequelae. Mature male rats were rendered cryptorchid and followed for up to nine weeks during which serial blood specimens were obtained for multiple hormonal analyses; serial testicular samples were obtained as well. In contrast with control ani... | [
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PMID:20821 | Blood-testis barrier: maintained function of inter-Sertoli cell junctions in experimental cryptorchidism in the rat, as judged by a simple lanthanum-immersion technique. | In order to elucidate the mechanisms behind the deleterious effects on the germinal epithelium of experimental cryptorchidism the hypothesis that a leaking blood-testis barrier is the cause of the damage was tested. The permeability of the specialized inter-Sertoli cell junctions to lanthanum after experimental cryptor... | Blood-testis barrier: maintained function of inter-Sertoli cell junctions in experimental cryptorchidism in the rat, as judged by a simple lanthanum-immersion technique. In order to elucidate the mechanisms behind the deleterious effects on the germinal epithelium of experimental cryptorchidism the hypothesis that a le... | [
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PMID:20824 | Oxygen uptake of canine whole body and hind limb with hypocapnic alkalosis. | The effect of hypocapnic alkalosis induced by hyperventilation on whole-body and hind-limb oxygen uptake (VO2) was studied in dogs anesthetized with pentobarbital. In the intact dog with a self-perfused hind limb, increasing pHa from 7.41 to 7.58 increased whole-body VO2 8% and decreased hind-limb VO2 6%. Isolated hind... | Oxygen uptake of canine whole body and hind limb with hypocapnic alkalosis. The effect of hypocapnic alkalosis induced by hyperventilation on whole-body and hind-limb oxygen uptake (VO2) was studied in dogs anesthetized with pentobarbital. In the intact dog with a self-perfused hind limb, increasing pHa from 7.41 to 7.... | [
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PMID:20823 | Control of gastric acidity by glycopyrrolate premedication in the parturient. | The effect of premedication with the anticholinergic quaternary ammonium compound, glycopyrrolate (0.4 mg), on gastric juice pH was investigated in 23 parturients scheduled for elective cesarean section under general anesthesia, and the results were compared to a control group of 15 nonpremedicated obstetric patients a... | Control of gastric acidity by glycopyrrolate premedication in the parturient. The effect of premedication with the anticholinergic quaternary ammonium compound, glycopyrrolate (0.4 mg), on gastric juice pH was investigated in 23 parturients scheduled for elective cesarean section under general anesthesia, and the resul... | [
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PMID:20828 | Dirofilaria immitis and its potential mosquito vectors in central New York State. | Screening of 25,822 dog blood samples indicated approximately a 1% infection rate with Dirofilaria immitis. Dipetalonema reconditum microfilariae were found in approximately 2% of 1,876 feral dogs examined. Laboratory experimentation indicated that 6 of 10 local mosquito species examined allowed successful extrinsic in... | Dirofilaria immitis and its potential mosquito vectors in central New York State. Screening of 25,822 dog blood samples indicated approximately a 1% infection rate with Dirofilaria immitis. Dipetalonema reconditum microfilariae were found in approximately 2% of 1,876 feral dogs examined. Laboratory experimentation indi... | [
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PMID:20834 | [Effect of tetracycline base crystallization on the conditions properties of the powders and drug forms obtained. The development of directed crystallization procedures for tetracycline base]. | The study of the process of tetracycline base crystallization showed that with an increase in the rate of pH, temperature and mixed rotation changes, the specific surface of the crystalline precipitate increased with a simultaneous decrease in the bulk weight, looseness and volume density of the powder. The residual co... | [Effect of tetracycline base crystallization on the conditions properties of the powders and drug forms obtained. The development of directed crystallization procedures for tetracycline base]. The study of the process of tetracycline base crystallization showed that with an increase in the rate of pH, temperature and m... | [
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PMID:20835 | [Side effects of antibiotics in rheumatic diseases]. | Complications due to antibiotic therapy in rheumatic patients subjected to season bicillin prophylaxis in Minsk within 1965--1975 and in patients with extensive collagenoses were studied. Allergic complications mainly ih the form of allergic reactions in the patients treated with bicillin-3 or picillin-5 were observed ... | [Side effects of antibiotics in rheumatic diseases]. Complications due to antibiotic therapy in rheumatic patients subjected to season bicillin prophylaxis in Minsk within 1965--1975 and in patients with extensive collagenoses were studied. Allergic complications mainly ih the form of allergic reactions in the patients... | [
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PMID:20836 | [Effect of the crystallization conditions of tetracycline base on the properties of the powders and drug forms obtained. The dependence of the degree of dispersion of tetracycline base on the crystallization conditions]. | Characteristics of the powder dispersity of tetracycline base samples prepared by directed crystallization with variation of the process conditions were determined by the sedimentation method. It was found that the speed of the solution agitation had the maximum effect on the level and nature of the dispersity. The rat... | [Effect of the crystallization conditions of tetracycline base on the properties of the powders and drug forms obtained. The dependence of the degree of dispersion of tetracycline base on the crystallization conditions]. Characteristics of the powder dispersity of tetracycline base samples prepared by directed crystall... | [
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PMID:20837 | Conditional killing effect of staphylococcin 1580 and repair of sublethal injury in Staphylococcus aureus. | Treatment of sensitive cells with staphylococcin 1580, a bacteriocin of Staphylococcus epidermidis, rapidly induced gross changes in the permeability of the membrane. However, only a small fraction of the cells was killed when treated cells were plated on media containing low amounts of salts. Killing was greatly enhan... | Conditional killing effect of staphylococcin 1580 and repair of sublethal injury in Staphylococcus aureus. Treatment of sensitive cells with staphylococcin 1580, a bacteriocin of Staphylococcus epidermidis, rapidly induced gross changes in the permeability of the membrane. However, only a small fraction of the cells wa... | [
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PMID:20838 | Occurrence and distribution of bacterial indicators and pathogens in canal communities along the Texas coast. | Increased construction of residential canal communities along the southern coastline of the United States has led to a concern about their impact on water quality. Pollution of such dead-end canals is potentially hazardous because of their heavy usage for recreational activities. Coliforms, fecal coliforms, and salmone... | Occurrence and distribution of bacterial indicators and pathogens in canal communities along the Texas coast. Increased construction of residential canal communities along the southern coastline of the United States has led to a concern about their impact on water quality. Pollution of such dead-end canals is potential... | [
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PMID:20839 | Development of a quantitative method for detecting enteroviruses in estuarine sediments. | Several investigators have reported on the detection of enteric viruses in marine sediments, but none determined the efficiency of their methods and only limited volumes of sediment were sampled. The purpose of this investigation was to develop a quantitative method for detecting enteroviruses in marine sediments so th... | Development of a quantitative method for detecting enteroviruses in estuarine sediments. Several investigators have reported on the detection of enteric viruses in marine sediments, but none determined the efficiency of their methods and only limited volumes of sediment were sampled. The purpose of this investigation w... | [
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PMID:20840 | Production of beta-galactosidase from Streptococcus thermophilus grown in whey. | beta-D-Galactosidase (EC 3.2.1.23) was extracted from Streptococcus thermophilus grown in deproteinized cheese whey. Cultural conditions optimum for maximum enzyme production were pH 7.0, 40 degrees C, and 24 h. Proteose peptone (2.0%, wt/vol) and corn steep liquor (2.8%, wt/vol) were highly stimulatory, increasing the... | Production of beta-galactosidase from Streptococcus thermophilus grown in whey. beta-D-Galactosidase (EC 3.2.1.23) was extracted from Streptococcus thermophilus grown in deproteinized cheese whey. Cultural conditions optimum for maximum enzyme production were pH 7.0, 40 degrees C, and 24 h. Proteose peptone (2.0%, wt/v... | [
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PMID:20854 | Scleroderma-like changes in chronic graft vs host disease. | A case of chronic graft vs host disease had scleroderma-like skin changes. Clinical progression was from poikiloderma to scleroderma, and histopathological changes and results of direct immunofluorescence were noted. It is probable that both cell-mediated (T-cell) and humoral (B-cell) mechanisms contribute to the patho... | Scleroderma-like changes in chronic graft vs host disease. A case of chronic graft vs host disease had scleroderma-like skin changes. Clinical progression was from poikiloderma to scleroderma, and histopathological changes and results of direct immunofluorescence were noted. It is probable that both cell-mediated (T-ce... | [
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PMID:20856 | Long-term esophageal function following repair of esophageal atresia. | Primary repair of esophageal atresia restores gastrointestinal continuity, but does not ensure normal esophageal function. To date 22 patients, six to 32 (average 15) years after repair of their esophageal atresias, have been evaluated by personal interview and esophageal manometrics and acid reflux testing. Previous b... | Long-term esophageal function following repair of esophageal atresia. Primary repair of esophageal atresia restores gastrointestinal continuity, but does not ensure normal esophageal function. To date 22 patients, six to 32 (average 15) years after repair of their esophageal atresias, have been evaluated by personal in... | [
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PMID:20857 | Interaction of drugs with apomorphine, tryptamine and norepinephrine. A new 'in vivo' approach: the ATN-test in rats. | A new experimental test procedure is described for the 'in vivo' study of drug interactions with dopamine (DA), 5 hydroxy-tryptamine (5-HT) and norepinephrine (NE). The ultimate aim of this study is to provide an empirical evaluation of the relative specificity with which drugs may affect particular neurotransmitter sy... | Interaction of drugs with apomorphine, tryptamine and norepinephrine. A new 'in vivo' approach: the ATN-test in rats. A new experimental test procedure is described for the 'in vivo' study of drug interactions with dopamine (DA), 5 hydroxy-tryptamine (5-HT) and norepinephrine (NE). The ultimate aim of this study is to ... | [
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PMID:20858 | Cilioinhibitory effect of phenothiazines in vitro and its antagonism by Ca++. | The inhibition of ciliary beating in vitro by physiologic concentrations of chlorpromazine (CPZ) and prochlorperazine (PCP) was demonstrated in two experimental systems. CPZ had a greater cilioinhibitory effect than PCP on the rotational velocity of tissue explants from the frog palate in amphibian Ringers, and on the ... | Cilioinhibitory effect of phenothiazines in vitro and its antagonism by Ca++. The inhibition of ciliary beating in vitro by physiologic concentrations of chlorpromazine (CPZ) and prochlorperazine (PCP) was demonstrated in two experimental systems. CPZ had a greater cilioinhibitory effect than PCP on the rotational velo... | [
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0.08... |
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