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PMID:9772 | Dissolution rate of cadmium from dental gold solder alloys. | The dissolution rate of cadmium from six different dental gold solder alloys was determined in an in vitro potentiostatic study. The measurements were made in the potential range 740--880 mV and attempts have been made to extrapolate the results to a potential region that might in reality occur in the oral cavity. For ... | Dissolution rate of cadmium from dental gold solder alloys. The dissolution rate of cadmium from six different dental gold solder alloys was determined in an in vitro potentiostatic study. The measurements were made in the potential range 740--880 mV and attempts have been made to extrapolate the results to a potential... | [
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PMID:9769 | Preliminary report: parenteral Lorazepam in induced epileptic states in man. | The anticonvulsive effect of Lorazepam -- one of the newer diazepines -- has been tested in 10 patients with induced epileptic conditions under continuous polygraphic control. The quantitative analysis of the paroxysmal discharges -- i.e. the evolution of the "paroxysmal index" -- shows that 5 mg IV Lorazepam normalize... | Preliminary report: parenteral Lorazepam in induced epileptic states in man. The anticonvulsive effect of Lorazepam -- one of the newer diazepines -- has been tested in 10 patients with induced epileptic conditions under continuous polygraphic control. The quantitative analysis of the paroxysmal discharges -- i.e. the ... | [
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PMID:9773 | The correlation between salivary peroxidase activity, salivary flow rate, and the oxidation-reduction potentials of human saliva and dental plaque suspensions. | 18 subjects, 9 males and 9 females, were examined regarding salivary oxidation-reduction potential, salivary flow rate, salivary peroxidase activity, oxidation-reduction potential of dental plaque samples, and dental health. Both the peroxidase activity, expressed as the salivary lactoperoxidase, and the salivary oxida... | The correlation between salivary peroxidase activity, salivary flow rate, and the oxidation-reduction potentials of human saliva and dental plaque suspensions. 18 subjects, 9 males and 9 females, were examined regarding salivary oxidation-reduction potential, salivary flow rate, salivary peroxidase activity, oxidation-... | [
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PMID:9774 | Rapid diagnosis of Enterobacteriaceae. I. Detection of bacterial glycosidases. | The paper describes a number of tests for the rapid detection of glycosidases including alpha-glucosidase, beta-glucosidase, beta-glucuronidase, beta-xylosidase and alpha-fucosidase. The methods use heavy suspensions of viable but non-multiplying bacteria in a buffered solution of a chromogenic substrate. The results o... | Rapid diagnosis of Enterobacteriaceae. I. Detection of bacterial glycosidases. The paper describes a number of tests for the rapid detection of glycosidases including alpha-glucosidase, beta-glucosidase, beta-glucuronidase, beta-xylosidase and alpha-fucosidase. The methods use heavy suspensions of viable but non-multip... | [
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PMID:9775 | Proteolytic degradation of staphylococcal alpha-toxin. | Staphylococcal alpha-toxin of mol.wt. 39,000 was degraded at an alkaline pH by staphylococcal extracellular proteases resulting in the formation of three relatively stable intermediates with mol.wt. 27,500, 23,500 and 12,000. The intermediate with mol.wt. 27,500 which existed in two charged forms, was isolated by colum... | Proteolytic degradation of staphylococcal alpha-toxin. Staphylococcal alpha-toxin of mol.wt. 39,000 was degraded at an alkaline pH by staphylococcal extracellular proteases resulting in the formation of three relatively stable intermediates with mol.wt. 27,500, 23,500 and 12,000. The intermediate with mol.wt. 27,500 wh... | [
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PMID:9776 | Glycerol transport in human red cells. | The kinetics of 14C-glycerol exchange was studied in human red cells. Glycerol appeared to be transported by two mechanisms: (i) by facilitated diffusion with permeability depending on glycerol concentration, and (ii) by an unspecific pathway, presumably representing the diffusion of individual glycerol molecules throu... | Glycerol transport in human red cells. The kinetics of 14C-glycerol exchange was studied in human red cells. Glycerol appeared to be transported by two mechanisms: (i) by facilitated diffusion with permeability depending on glycerol concentration, and (ii) by an unspecific pathway, presumably representing the diffusion... | [
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PMID:9777 | Significance of the extracellular bicarbonate buffer system to anaerobic glycolysis in hypoxic muscle. | 1. The influence of the carbon dioxide-bicarbonate buffer system on anaerobic energy production during severe hypoxia was studied in isolated right hemidiaphragms of rats.--2. When the tissue was incubated in a Ringer solution containing 25 mM HCO-3 aerated with 7% CO2 in N2 at pH 7.4, the lactate production and lactat... | Significance of the extracellular bicarbonate buffer system to anaerobic glycolysis in hypoxic muscle. 1. The influence of the carbon dioxide-bicarbonate buffer system on anaerobic energy production during severe hypoxia was studied in isolated right hemidiaphragms of rats.--2. When the tissue was incubated in a Ringer... | [
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PMID:9778 | Influence of adipose tissue blood flow on the lipolytic response to circulating noradrenaline at normal and reduced pH. | Hypercapnic acidosis (pH 7.0) inhibits the lipolytic response of canine subcutaneous adipose tissue to i.v. infused noradrenaline (NA) by 80 per cent or more. The response to sympathetic nerve stimulation, on the other hand, is only reduced by 10-40 per cent during acidosis. The fate of intravenously infused 3H-labelle... | Influence of adipose tissue blood flow on the lipolytic response to circulating noradrenaline at normal and reduced pH. Hypercapnic acidosis (pH 7.0) inhibits the lipolytic response of canine subcutaneous adipose tissue to i.v. infused noradrenaline (NA) by 80 per cent or more. The response to sympathetic nerve stimula... | [
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PMID:9779 | Contrast media with and without calcium for cardioangiography in children. | The possible beneficial effects of added calcium ions to contrast media to diminish myocardial toxicity was evaluated in 93 cardiac catheterizations with cardioangiography, performed in 50 children and adolescents. Two contrast media with equal iodine content (370 mg/ml) and similar physical properties were used: Isopa... | Contrast media with and without calcium for cardioangiography in children. The possible beneficial effects of added calcium ions to contrast media to diminish myocardial toxicity was evaluated in 93 cardiac catheterizations with cardioangiography, performed in 50 children and adolescents. Two contrast media with equal ... | [
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PMID:9780 | Influence of the cation on the side-effects of urographic contrast media. | The incidence of side-effects produced by meglumine diatrizoate and meglumine-, meglumine-calcium-, and sodium-calcium-magnesium metrizoate, was compared in 800 urographies. Patients older than 60 years seem to have less side-effects than younger patients. The incidence of sensation of warmth seems to be higher in pati... | Influence of the cation on the side-effects of urographic contrast media. The incidence of side-effects produced by meglumine diatrizoate and meglumine-, meglumine-calcium-, and sodium-calcium-magnesium metrizoate, was compared in 800 urographies. Patients older than 60 years seem to have less side-effects than younger... | [
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PMID:9781 | Regulation of lysine biosynthesis in Escherichia coli K12. | A general survey of the regulation in lysine biosynthesis in Escherichia coli K12 is presented. No polygenic operon exists for the genes that code for enzymes of the lysine biosynthetic pathway. Lysyl-tRNA is not directly involved as a co-repressor in the pathway. Different regulation mechanisms must exist for the diff... | Regulation of lysine biosynthesis in Escherichia coli K12. A general survey of the regulation in lysine biosynthesis in Escherichia coli K12 is presented. No polygenic operon exists for the genes that code for enzymes of the lysine biosynthetic pathway. Lysyl-tRNA is not directly involved as a co-repressor in the pathw... | [
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PMID:9783 | Regulation of tyrosine and phenylalanine biosynthesis in Salmonella. | Several types of 4-fluorophenylalanine resistant mutants were isolated. In one type of mutant DAHP synthetase (tyr) and prephenate dehydrogenase were coordinately derepressed. The mutation was linked to aroF and tyrA and was cis- dominant by merodiploid analysis, thus confirming that it is an operator constitutive muta... | Regulation of tyrosine and phenylalanine biosynthesis in Salmonella. Several types of 4-fluorophenylalanine resistant mutants were isolated. In one type of mutant DAHP synthetase (tyr) and prephenate dehydrogenase were coordinately derepressed. The mutation was linked to aroF and tyrA and was cis- dominant by merodiplo... | [
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PMID:9794 | Blocking of olive oil induced plasma protein escape from the intestinal circulation by histamine antagonists and by a diamine oxidase releasing agent. | Earlier studies have shown that feeding of olive oil to rats substantially increased the plasma protein in the intestinal lymph. The possibility of histamine mediating this response was examined. The plasma protein escape from intestinal circulation after olive oil feeding was measured in rats in terms of the amount of... | Blocking of olive oil induced plasma protein escape from the intestinal circulation by histamine antagonists and by a diamine oxidase releasing agent. Earlier studies have shown that feeding of olive oil to rats substantially increased the plasma protein in the intestinal lymph. The possibility of histamine mediating t... | [
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PMID:9796 | Composition of the Zaysan virion. | The sedimentation coefficient of Zaysan virion ribonucleic acid (RNA), estimated by sucrose density gradient centrifugation, was 42 S. Pancreatic ribonuclease digested the viral RNA to acid-soluble fragments. Two viral structural proteins with apparent molecular weight of 50,000 and 30,000 daltons were identified by po... | Composition of the Zaysan virion. The sedimentation coefficient of Zaysan virion ribonucleic acid (RNA), estimated by sucrose density gradient centrifugation, was 42 S. Pancreatic ribonuclease digested the viral RNA to acid-soluble fragments. Two viral structural proteins with apparent molecular weight of 50,000 and 30... | [
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PMID:9797 | Morphological, cytological and biological observations on viruses isolated from patients with subacute thyroiditis de Quervain. | New data on viruses isolated from patients with subacute thyroiditis de Quervain are reported. Characteristic morphological, cytological, some physico-chemical and biological features of the isolated viruses are described. A possible role of these viruses in human and animal health disorders is discussed. The isolated ... | Morphological, cytological and biological observations on viruses isolated from patients with subacute thyroiditis de Quervain. New data on viruses isolated from patients with subacute thyroiditis de Quervain are reported. Characteristic morphological, cytological, some physico-chemical and biological features of the i... | [
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PMID:9798 | Interfering activity of virulent and attenuated influenza virus strains. | The interfering activity of influenza virus variants A/Hong Kong/1/68 (H3N202), A/Victoria/35/72(H3N2-3), B/14/55 and B/USSR/69 differing in the level of their reactogenicity for adults and children was studied. An inverse relationship was established between reactogenicity of the strains and their interfering activity... | Interfering activity of virulent and attenuated influenza virus strains. The interfering activity of influenza virus variants A/Hong Kong/1/68 (H3N202), A/Victoria/35/72(H3N2-3), B/14/55 and B/USSR/69 differing in the level of their reactogenicity for adults and children was studied. An inverse relationship was establi... | [
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PMID:9799 | Interference stimulated by tick-borne encephalitis virus: influence of divalent cations. | The effects of divalent cations (barium, cobalt, calcium, copper, magnesium, zinc and iron) on the interference of tick-borne encephalitis (TE) virus with vaccinia virus in Detroit-6 cell cultures were investigated. An increase in interference was shown in the presence of cobalt, zinc, copper, and magnesium. Barium and... | Interference stimulated by tick-borne encephalitis virus: influence of divalent cations. The effects of divalent cations (barium, cobalt, calcium, copper, magnesium, zinc and iron) on the interference of tick-borne encephalitis (TE) virus with vaccinia virus in Detroit-6 cell cultures were investigated. An increase in ... | [
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PMID:9800 | Autoantibodies in sera of influenza patients. | Sera of the influenza patients and healthy controls were tested for some types of autoantibody (SMA, ANA, ABBA, AMA). They were detected in 83.8% of the patients' sera and in 16.6% of controls. SMA were present in 77.4%, ANA in 54.8%, and ABBA in 16.1% of the patient's sera. AMA were not detected. A majority of the ser... | Autoantibodies in sera of influenza patients. Sera of the influenza patients and healthy controls were tested for some types of autoantibody (SMA, ANA, ABBA, AMA). They were detected in 83.8% of the patients' sera and in 16.6% of controls. SMA were present in 77.4%, ANA in 54.8%, and ABBA in 16.1% of the patient's sera... | [
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PMID:9801 | Latent pseudorabies virus infection in pigs. | Latent infection with the TOP strain of pseudorabies virus (PRV) was established in 6 weeks old piglets. Infectious virus was found in oropharyngeal swabs till day 10 post infection (p.i.); later on, attempts to detect the virus remained unsuccessful. However, PRV could be isolated by explantation of tonsils, cervical ... | Latent pseudorabies virus infection in pigs. Latent infection with the TOP strain of pseudorabies virus (PRV) was established in 6 weeks old piglets. Infectious virus was found in oropharyngeal swabs till day 10 post infection (p.i.); later on, attempts to detect the virus remained unsuccessful. However, PRV could be i... | [
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PMID:9802 | Experimental live tick-borne encephalitis vaccine (Labgat E5 "14" virus clone): volunteers 1 and 2 years after single-dose immunization. | Groups of volunteers given intramuscularly 5 or 6.5 dex or perorally 6.5 dex newborn mouse icLD50 of the plaquesegregated "14" clone of the Langat E5 virus strain (tick-borne encephalitis comples) were followed for periods of 12 and 24-27 months. Circulating specific virus neutralizing antibodies persisted in them in t... | Experimental live tick-borne encephalitis vaccine (Labgat E5 "14" virus clone): volunteers 1 and 2 years after single-dose immunization. Groups of volunteers given intramuscularly 5 or 6.5 dex or perorally 6.5 dex newborn mouse icLD50 of the plaquesegregated "14" clone of the Langat E5 virus strain (tick-borne encephal... | [
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PMID:9803 | Experimental infection of Macaca mulatta monkeys with Lednice (Yaba 1) virus. | Macaca mulatta monkeys were inoculated with Lednice (Yaba 1) virus strain 6118. The animals developed no clinical signs and the body temperature and values of complete haematological examination remained within normal limits. In spite of positive immunofluorescence in regional lymph nodes, no virus could be recovered f... | Experimental infection of Macaca mulatta monkeys with Lednice (Yaba 1) virus. Macaca mulatta monkeys were inoculated with Lednice (Yaba 1) virus strain 6118. The animals developed no clinical signs and the body temperature and values of complete haematological examination remained within normal limits. In spite of posi... | [
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PMID:9804 | A stable antibody-sensitized erythrocyte diagnostic preparation for detection of rhinovirus type 17 and its antibody. | A diagnostic preparation was obtained by sensitization of formalinized sheep erythrocytes with antibody to rhinovirus type 17. This preparation was agglutinated in the presence of relatively high concentrations of type 17 but not other types of rhinovirus. It could also be used for detection of antibody to rhinovirus t... | A stable antibody-sensitized erythrocyte diagnostic preparation for detection of rhinovirus type 17 and its antibody. A diagnostic preparation was obtained by sensitization of formalinized sheep erythrocytes with antibody to rhinovirus type 17. This preparation was agglutinated in the presence of relatively high concen... | [
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PMID:9805 | Soldado virus from Ornithodoros (Alectorobius) maritimus (Ixodoidea: Argasidae) infesting herring gull nests on Puffin Island, Northern Wales. | Three strains of Soldado (SOL) virus (Hughes serogroup) were isolated from nymphal and adult Ornithodoros (Alectorobius) maritimus Vermeil et Marguet collected in and near nests of the Herring Gull, Larus a. argentatus Pontoppidan, on Puffin Island, northern Wales. Reciprocal complement fixation (CF) titration results ... | Soldado virus from Ornithodoros (Alectorobius) maritimus (Ixodoidea: Argasidae) infesting herring gull nests on Puffin Island, Northern Wales. Three strains of Soldado (SOL) virus (Hughes serogroup) were isolated from nymphal and adult Ornithodoros (Alectorobius) maritimus Vermeil et Marguet collected in and near nests... | [
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PMID:9806 | Infection of Hela cells with a virulent and an attenuated strain of pseudorabies virus studied by electron microscopy. | Hollow-core particles, forming crystals in nuclei, prevailed in HeLa cells infected with an attenuated strain of pseudorabies virus (PRV). After infection with a virulent PRV strain, the cells contained mainly fully infectious dense-core particles. These findings might explain the lower susceptibility of HeLa and some ... | Infection of Hela cells with a virulent and an attenuated strain of pseudorabies virus studied by electron microscopy. Hollow-core particles, forming crystals in nuclei, prevailed in HeLa cells infected with an attenuated strain of pseudorabies virus (PRV). After infection with a virulent PRV strain, the cells containe... | [
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PMID:9807 | Respiratory syncytial virus-specific RNA synthesis in primary monkey kidney cell cultures. | Primary rhesus monkey kidney (MK) cell cultures were inoculated with respiratory syncytial virus and treated or untreated with actinomycin D before pulse labeling with uridine-5-3H. The virus-specific RNA synthesis was noted at its peak in the nucleoplasm and possibly less so in the cytoplasm of infected cells. At 48 a... | Respiratory syncytial virus-specific RNA synthesis in primary monkey kidney cell cultures. Primary rhesus monkey kidney (MK) cell cultures were inoculated with respiratory syncytial virus and treated or untreated with actinomycin D before pulse labeling with uridine-5-3H. The virus-specific RNA synthesis was noted at i... | [
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PMID:9808 | Cultivation of foot and mouth disease virus in bovine leukocyte cultures for use in the complement fixation test. | Bovine leukocyte cultures achieved good growth after 72 hours of cultivation. Foot-and mouth disease (FMD) virus type 0 multiplied in such cultures to a titre of 10(6) TCID50/0.1 ml. The cell culture-grown virus was found to be suitable for the complement fixation test (CFT) after purification and concentration with ca... | Cultivation of foot and mouth disease virus in bovine leukocyte cultures for use in the complement fixation test. Bovine leukocyte cultures achieved good growth after 72 hours of cultivation. Foot-and mouth disease (FMD) virus type 0 multiplied in such cultures to a titre of 10(6) TCID50/0.1 ml. The cell culture-grown ... | [
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PMID:9809 | Non-infectious tick-borne encephalitis antigen. | After formalin treatment of sucrose-acetone antigens, prepared from different tick-borne encephalitis (TBE) virus strains, their haemagglutination (HA) activity was preserved or even higher than that of untreated antigens. Formalin-treated TBE antigen was non-infectious and thus may be recommended for routine work to a... | Non-infectious tick-borne encephalitis antigen. After formalin treatment of sucrose-acetone antigens, prepared from different tick-borne encephalitis (TBE) virus strains, their haemagglutination (HA) activity was preserved or even higher than that of untreated antigens. Formalin-treated TBE antigen was non-infectious a... | [
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PMID:9816 | Molecular weight analysis of the polypeptides of cholera phage PL 163/10 by polyacrylamide gel electrophoresis. | Cholera phage PL 163/10, belonging to Mukerjee's Group I, was purified by alternate cycles of low and high speed centrifugation. Gel electrophoresis revealed the presence of four polypeptide chains of respective molecular weights of 10,370+/-515 (A), 30,000+/-1,303 (B), 40,000+/-1,049(C) and 64,000+/-2,433 (D) daltons.... | Molecular weight analysis of the polypeptides of cholera phage PL 163/10 by polyacrylamide gel electrophoresis. Cholera phage PL 163/10, belonging to Mukerjee's Group I, was purified by alternate cycles of low and high speed centrifugation. Gel electrophoresis revealed the presence of four polypeptide chains of respect... | [
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PMID:9817 | Investigation on the biological activity of fowl plague virus ribonucleoprotein. | Fowl plague virus (FPV) ribonucleoprotein (RNP) bands in sucrose density gradient in a heterogeneous peak with sedimentation coefficients from 45 to 70 S, whereas in cesium chloride gradient it has a homogeneous density of 1.33-1.34 g/cm3. FPV RNP contains 7.4-8% RNA. Upon inoculation of chick embryo cell cultures. FPV... | Investigation on the biological activity of fowl plague virus ribonucleoprotein. Fowl plague virus (FPV) ribonucleoprotein (RNP) bands in sucrose density gradient in a heterogeneous peak with sedimentation coefficients from 45 to 70 S, whereas in cesium chloride gradient it has a homogeneous density of 1.33-1.34 g/cm3.... | [
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PMID:9818 | Interaction of plasma membranes with influenza virus. VI. The possible role of the adenylate cyclase system. | The amounts of released soluble (s) antigen of influenza A/WSN virus were increased when the virus was allowed to interact with isolated plasma membranes in a medium containing substances enhancing the level of adenosine 3',5' cyclic monophosphate (c'AMP) or activating the enzyme adenylate cyclase. By contrast, less s-... | Interaction of plasma membranes with influenza virus. VI. The possible role of the adenylate cyclase system. The amounts of released soluble (s) antigen of influenza A/WSN virus were increased when the virus was allowed to interact with isolated plasma membranes in a medium containing substances enhancing the level of ... | [
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PMID:9819 | Virion heat-sensitivity of adenovirus type 5 temperature-sensitive mutants and interferon induction. | Kinetics of interferon induction with wild type adenovirus 5, and three temperature-sensitive mutants, ts 1, ts 18 and ts 19 were examined in chick embryo cells (CEC) at permissive (31 degrees C) and non-permissive (38 degrees C) temperatures. Interferon levels reached a maximum four days after infection with the wild ... | Virion heat-sensitivity of adenovirus type 5 temperature-sensitive mutants and interferon induction. Kinetics of interferon induction with wild type adenovirus 5, and three temperature-sensitive mutants, ts 1, ts 18 and ts 19 were examined in chick embryo cells (CEC) at permissive (31 degrees C) and non-permissive (38 ... | [
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PMID:9820 | Ts mutant of NWS influenza virus: behaviour in vitro and in vivo. | After passaging the NWS influenza virus at increasing temperatures in the hamster embryo fibroblast (HEF) cell line, a temperature-resistant (tr) mutant which grew well at 39 degrees C was isolated. Attempts were made to isolate temperature-sensitive (ts) mutants from the tr virus. After growth in the presence of 5-flu... | Ts mutant of NWS influenza virus: behaviour in vitro and in vivo. After passaging the NWS influenza virus at increasing temperatures in the hamster embryo fibroblast (HEF) cell line, a temperature-resistant (tr) mutant which grew well at 39 degrees C was isolated. Attempts were made to isolate temperature-sensitive (ts... | [
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PMID:9821 | Replication dynamics of tick-borne encephalitis virus in, and glycolytic activity of, human diploid cells. | Tick-borne encephalitis (TBE) virus (Western subtype) strains replicated very rapidly in human diploid embryonic lung (HDEL) cells, namely within the first 24 hours of infection. Greater amounts of both intra- and extracellular virus were produced after inoculation of a virulent than of an attenuated strain. With the v... | Replication dynamics of tick-borne encephalitis virus in, and glycolytic activity of, human diploid cells. Tick-borne encephalitis (TBE) virus (Western subtype) strains replicated very rapidly in human diploid embryonic lung (HDEL) cells, namely within the first 24 hours of infection. Greater amounts of both intra- and... | [
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PMID:9822 | Affinity chromatography of mouse interferon: a modified purification procedure utilizing specifically purified antibodies. | Interferon preparations of a high degree of purity were obtained by a one-step procedure using affinity chromatography on specifically purified immunoadsorbent. The procedure consisted of binding interferon harvested from serum-free medium and purified by Zn-acetate precipitation and SP-Sephadex chromatography to CNBr-... | Affinity chromatography of mouse interferon: a modified purification procedure utilizing specifically purified antibodies. Interferon preparations of a high degree of purity were obtained by a one-step procedure using affinity chromatography on specifically purified immunoadsorbent. The procedure consisted of binding i... | [
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PMID:9823 | Use of cross-linking in studying the structure of RNA tumour viruses. | Treatment of intact avian myeloblastosis virus (AMV) with dimethyl suberimidate dihydrochloride (DMS), a cross-linking agent specific for amino groups, was found to result in progressive cross-linking among viral proteins, as revealed by polyacrylamide gel electrophoresis (PAGE) in the presence of sodium dodecyl sulpha... | Use of cross-linking in studying the structure of RNA tumour viruses. Treatment of intact avian myeloblastosis virus (AMV) with dimethyl suberimidate dihydrochloride (DMS), a cross-linking agent specific for amino groups, was found to result in progressive cross-linking among viral proteins, as revealed by polyacrylami... | [
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PMID:9824 | Eyach--an arthropod-borne virus related to Colorado tick fever virus in the Federal Republic of Germany. | From Ixodes ricinus ticks collected in a tick-borne encephalitis focus in Baden-Württemberg, an agent pathogenic exclusively for suckling mice was isolated. Obviously a virus, it passed membrane filters with a pore width of 200 nm. It was resistant to ether and sodium deoxycholate, but not to chloroform. In the complem... | Eyach--an arthropod-borne virus related to Colorado tick fever virus in the Federal Republic of Germany. From Ixodes ricinus ticks collected in a tick-borne encephalitis focus in Baden-Württemberg, an agent pathogenic exclusively for suckling mice was isolated. Obviously a virus, it passed membrane filters with a pore ... | [
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PMID:9825 | Effect of adamantane derivatives on the activity of orthomyxovirus RNA-dependent RNA polymerase. | The effect of several adamantane derivatives on the activity of virion-associated RNA-dependent RNA polymerase of fowl plague virus (FPV) and influenza B virus was studied in vitro. Some of the derivatives inhibited the activity of the polymerase by 60 per cent. A correlation was established between the previously demo... | Effect of adamantane derivatives on the activity of orthomyxovirus RNA-dependent RNA polymerase. The effect of several adamantane derivatives on the activity of virion-associated RNA-dependent RNA polymerase of fowl plague virus (FPV) and influenza B virus was studied in vitro. Some of the derivatives inhibited the act... | [
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PMID:9826 | Increased resistance of an interferon-resistant cell subline to the toxic effect of double-stranded RNA. | The toxicity of double-stranded (ds) f2-phage RNA for interferon-treated L cells and an interferon-resistant subline of L cells (CVS cells) was compared. The interferon-resistant subline proved to be about 20 times more resistant to ds RNA than the parent L cells. The degree of toxicity of ds RNA was dependent on the c... | Increased resistance of an interferon-resistant cell subline to the toxic effect of double-stranded RNA. The toxicity of double-stranded (ds) f2-phage RNA for interferon-treated L cells and an interferon-resistant subline of L cells (CVS cells) was compared. The interferon-resistant subline proved to be about 20 times ... | [
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PMID:9827 | [Some aspects of phylogenetic development of cellular immune reaction in vertebrates]. | The division of the immune system into humoral and cell-mediated immunity is established in vertebrates. Moreover single manifestations of cell-mediated immunity are observed in invertebrates, too. In protochordates, e.g., a genetically fixed ability to recognize "Self" and "Not-Self" could already be demonstrated, but... | [Some aspects of phylogenetic development of cellular immune reaction in vertebrates]. The division of the immune system into humoral and cell-mediated immunity is established in vertebrates. Moreover single manifestations of cell-mediated immunity are observed in invertebrates, too. In protochordates, e.g., a genetica... | [
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PMID:9828 | Evaluation of serum ionic calcium measurement in a general hospital population. | Direct measurement of ionic calcium was evaluated in light of conflicting reports concerning the correlation of ionic calcium with total calcium and ionic calcium as predicted from total calcium and serum protein. Ionic calcium in the sera of normo- hypo-, and hypercalcemic adult hospitalized patients was measured anae... | Evaluation of serum ionic calcium measurement in a general hospital population. Direct measurement of ionic calcium was evaluated in light of conflicting reports concerning the correlation of ionic calcium with total calcium and ionic calcium as predicted from total calcium and serum protein. Ionic calcium in the sera ... | [
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PMID:9829 | Stability of several brands of ampicillin and penicillin V potassium oral liquids following reconstitution. | The stability-time profiles of the active ingredient of five generically equivalent brands of penicillin V potassium for oral solution, and of five generically equivalent brands of ampicillin for oral suspension, were studied. Three controlled conditions were employed-refrigerated, room and elevated temperature-and all... | Stability of several brands of ampicillin and penicillin V potassium oral liquids following reconstitution. The stability-time profiles of the active ingredient of five generically equivalent brands of penicillin V potassium for oral solution, and of five generically equivalent brands of ampicillin for oral suspension,... | [
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PMID:9832 | Comparison of microelectrode, DMO, and methylamine methods for measuring intracellular pH. | The intracellular pH (pHi) of giant barnacle muscle fibers was measured with glass microelectrodes and also calculated from the distribution of 5,5-dimethyl-2,4-oxazolidinedione (DMO) and methylamine (MA). Simultaneously applying any two of these methods to muscle fibers of the same barnacle, we found the pH measured w... | Comparison of microelectrode, DMO, and methylamine methods for measuring intracellular pH. The intracellular pH (pHi) of giant barnacle muscle fibers was measured with glass microelectrodes and also calculated from the distribution of 5,5-dimethyl-2,4-oxazolidinedione (DMO) and methylamine (MA). Simultaneously applying... | [
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PMID:9833 | Cardiovascular and metabolic responses during burn shock in the guinea pig. | The hemodynamic and metabolic responses of fatally burned, nonfatally burned, and unburned control guinea pigs were compared. The burns were induced in temporarily anesthetized animals by immersion to either the xyphoid process (70% fatal) or the midabdomen (100%survival) in boiling water for 3 s. Although cardiac outp... | Cardiovascular and metabolic responses during burn shock in the guinea pig. The hemodynamic and metabolic responses of fatally burned, nonfatally burned, and unburned control guinea pigs were compared. The burns were induced in temporarily anesthetized animals by immersion to either the xyphoid process (70% fatal) or t... | [
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PMID:9834 | Autoregulation of cerebral blood flow and its relation to cerebrospinal fluid pH. | Internal carotid artery blood flow (IFBF) was determined in each of nine Macaca mulatta by means of a flow transducer implanted around an internal carotid artery. The monkeys were lightly anesthetized, intubated, and paralyzed. Normoxia and normocarbia were maintained stable throughout the experiment. ICBF was monitore... | Autoregulation of cerebral blood flow and its relation to cerebrospinal fluid pH. Internal carotid artery blood flow (IFBF) was determined in each of nine Macaca mulatta by means of a flow transducer implanted around an internal carotid artery. The monkeys were lightly anesthetized, intubated, and paralyzed. Normoxia a... | [
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PMID:9835 | Characteristics of phosphate transport in isolated proximal tubule. | The characteristics of inorganic phosphate transport in isolated perfused proximal tubules of the rabbit were examined using radioisotopic techniques. When tubules were perfused with an ultrafiltrate of rabbit serum, the mean lumen-to-bath flux of phosphate in the convoluted segment was 6.60 +/- 1.41 (SE) pmol/mm-min w... | Characteristics of phosphate transport in isolated proximal tubule. The characteristics of inorganic phosphate transport in isolated perfused proximal tubules of the rabbit were examined using radioisotopic techniques. When tubules were perfused with an ultrafiltrate of rabbit serum, the mean lumen-to-bath flux of phos... | [
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PMID:9836 | Atypical facial pain as a defense against psychosis. | The author describes three women who presented psychotic symptoms 24--48 hours before scheduled neurosurgical procedures for atypical facial pain; all had had extensive dental reconstruction and attempted nerve blocks with no relief. Psychiatric hospitalization and administration of major tranquilizers resulted in cont... | Atypical facial pain as a defense against psychosis. The author describes three women who presented psychotic symptoms 24--48 hours before scheduled neurosurgical procedures for atypical facial pain; all had had extensive dental reconstruction and attempted nerve blocks with no relief. Psychiatric hospitalization and a... | [
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PMID:9838 | The effect of lorazepam on the vasoconstriction of fear. | Volume-pulse digital plethysmography performed under ideal conditions on relatively fit adults has shown that lorazepam 4 mg intravenously abolishes the vasoconstriction of fear and restores the digital vasodilatation of the tranquil mind. The sedative effect of the drug is prolonged and is associated with several hour... | The effect of lorazepam on the vasoconstriction of fear. Volume-pulse digital plethysmography performed under ideal conditions on relatively fit adults has shown that lorazepam 4 mg intravenously abolishes the vasoconstriction of fear and restores the digital vasodilatation of the tranquil mind. The sedative effect of ... | [
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PMID:9839 | Anaesthesia for Caesarean section with ketamine. | Fifty healthy mothers, with normal placental function, were anaesthetised with ketamine for Caesarean section. Anaesthesia was maintained with nitrous oxide, oxygen, muscle relaxants and controlled ventilation. Surgery was conducted in the lateral tilt position. Arterial blood samples were drawn from the mothers, and f... | Anaesthesia for Caesarean section with ketamine. Fifty healthy mothers, with normal placental function, were anaesthetised with ketamine for Caesarean section. Anaesthesia was maintained with nitrous oxide, oxygen, muscle relaxants and controlled ventilation. Surgery was conducted in the lateral tilt position. Arterial... | [
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PMID:9840 | Preoperative magnesium trisilicate in infants. | Three groups, each of forty children aged less than five years and prepared for elective surgery, had their gastric contents' volume and pH measured. The control group showed an incidence of 67-5 per cent with high acidity (pH equal to or less than 2-5). In the second and third groups magnesium trisilicate mixture was ... | Preoperative magnesium trisilicate in infants. Three groups, each of forty children aged less than five years and prepared for elective surgery, had their gastric contents' volume and pH measured. The control group showed an incidence of 67-5 per cent with high acidity (pH equal to or less than 2-5). In the second and ... | [
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PMID:9841 | A diagram to facilitate the understanding and therapy of mixed acid base disorders. | A diagram based on in-vivo relationships between arterial hydrogen ion activity (H+) and carbon dioxide tension (PCO2) in primary abnormalities of acid base homeostasis is presented. It is designed to facilitate the interpretation of pH data by including the 95% confidence limits described in patients with simple metab... | A diagram to facilitate the understanding and therapy of mixed acid base disorders. A diagram based on in-vivo relationships between arterial hydrogen ion activity (H+) and carbon dioxide tension (PCO2) in primary abnormalities of acid base homeostasis is presented. It is designed to facilitate the interpretation of pH... | [
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PMID:9844 | Molecular mechanisms of nerve block by local anesthetics. | Local anesthetics block nerve conduction by preventing the increase in membrane permeability to sodium ions that normally leads to a nerve impulse. Among anesthetics containing tertiary amine groups, the cationic, protonated form appears to be more active than the neutral form. However, the neutral forms, as well as un... | Molecular mechanisms of nerve block by local anesthetics. Local anesthetics block nerve conduction by preventing the increase in membrane permeability to sodium ions that normally leads to a nerve impulse. Among anesthetics containing tertiary amine groups, the cationic, protonated form appears to be more active than t... | [
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PMID:9845 | Further studies of the anti-recall effect of lorazepam: A dose--time--effect relationship. | The time of onset and duration of the anti-recall action of lorazepam were assessed under clinical conditions by measuring recall and recognition of visual stimuli 24 hours after intravenous administration of lorazepam. The visual stimuli were first presented 5-240 minutes after 2 mg and 5-360 minutes after 4 mg loraze... | Further studies of the anti-recall effect of lorazepam: A dose--time--effect relationship. The time of onset and duration of the anti-recall action of lorazepam were assessed under clinical conditions by measuring recall and recognition of visual stimuli 24 hours after intravenous administration of lorazepam. The visua... | [
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PMID:9846 | Influence of anesthetic agent on survival following hemorrhage. | One hundred and twenty-eight Sprague-Dawley rats were each anesthetized with one of four anaesthetics and subjected to a standard hemorrhage protocol to determine the effects of anesthetics on survival following hemorrhage. The anesthetics studied were: halothane, 1.26 vol per cent; fluroxene, 4.5 vol per cent; pentoba... | Influence of anesthetic agent on survival following hemorrhage. One hundred and twenty-eight Sprague-Dawley rats were each anesthetized with one of four anaesthetics and subjected to a standard hemorrhage protocol to determine the effects of anesthetics on survival following hemorrhage. The anesthetics studied were: ha... | [
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PMID:9851 | [Structure of the interalveolar wall]. | The wall, which unites as well as separates two contiguous pulmonary alveoli is composed of: - a conjuntival partition, the veritable skeleton of the wall, which is occupied, to the largest extent, by capillary blood vessels. Between the capillaries, conjunctival cells are dispursed: fibrocytes, fibroblasts and histioc... | [Structure of the interalveolar wall]. The wall, which unites as well as separates two contiguous pulmonary alveoli is composed of: - a conjuntival partition, the veritable skeleton of the wall, which is occupied, to the largest extent, by capillary blood vessels. Between the capillaries, conjunctival cells are dispurs... | [
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PMID:9852 | [Pulmonary edemas of drownings]. | Patients who are victims of near drowning in fresh water or salt water very frequently have acute edema of the lung which occurs either immediately, or after a free interval of variable duration. The mechanism of this edema is explained, in near drowning in salt water, by the hyperosmolarity of the alveolar fluid leadi... | [Pulmonary edemas of drownings]. Patients who are victims of near drowning in fresh water or salt water very frequently have acute edema of the lung which occurs either immediately, or after a free interval of variable duration. The mechanism of this edema is explained, in near drowning in salt water, by the hyperosmol... | [
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PMID:9853 | [Pulmonary edemas. Classification and mechanisms]. | Water exchanges in the lung under physiological conditions, are still badly known. Starling's classical equation is a too simplified view of the phenomenon. In addition, a certain number of its factors are badly determined. Such is the case with the hydrostatic pressure and the oncotic pressure of the interstitium. In ... | [Pulmonary edemas. Classification and mechanisms]. Water exchanges in the lung under physiological conditions, are still badly known. Starling's classical equation is a too simplified view of the phenomenon. In addition, a certain number of its factors are badly determined. Such is the case with the hydrostatic pressur... | [
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PMID:9854 | [High altitude acute pulmonary edema (author's transl)]. | HAAPE has been recognised only recently but is of real interest as much from the clinical as well as the dogmatic stand-point owing to the complexity of its physiopathological findings. It is encountered at altitudes higher than 4,000 meters either during a first contact or in natives returning from low altitude zones.... | [High altitude acute pulmonary edema (author's transl)]. HAAPE has been recognised only recently but is of real interest as much from the clinical as well as the dogmatic stand-point owing to the complexity of its physiopathological findings. It is encountered at altitudes higher than 4,000 meters either during a first... | [
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PMID:9855 | [Pulmonary edemas of infectious origin]. | Diffuse pulmonary edema, capable of arising in the absence of hemodynamic disorders is rare in infectious disease. They take on two different clinical appearances: a) acute edema of the lung with the syndrome of asphysia, b) a subacute dyspneic pneumonia with hypoxemia and hypo or normocapnia. These initial disorders c... | [Pulmonary edemas of infectious origin]. Diffuse pulmonary edema, capable of arising in the absence of hemodynamic disorders is rare in infectious disease. They take on two different clinical appearances: a) acute edema of the lung with the syndrome of asphysia, b) a subacute dyspneic pneumonia with hypoxemia and hypo ... | [
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PMID:9856 | [Hemodynamic data in lesional pulmonary edemas]. | Pulmonary edema due to disorders in alveolo-capillary permeability (or lesional) are differentiated from hemodynamic pulmonary edema by the fact that they arise in spite of normal pulmonary capillary pressure (PCP). A hemodynamic study was carried out in 42 cases of lesional P.E. The PCP was normal whatever the date of... | [Hemodynamic data in lesional pulmonary edemas]. Pulmonary edema due to disorders in alveolo-capillary permeability (or lesional) are differentiated from hemodynamic pulmonary edema by the fact that they arise in spite of normal pulmonary capillary pressure (PCP). A hemodynamic study was carried out in 42 cases of lesi... | [
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PMID:9858 | [Blood gas determination and calculation of shunts in nonhemodynamic pulmonary edemas]. | Qs/Qt is usually determined by the "oxygen" method. The standard equation for calculation of percentage shunts is therefore: (see article) In the case for an FiO2 of I and when PaO2 is greater than 150 mm Hg, the equation can be expressed in terms of the difference in partial pressures of oxygen between the alveolus an... | [Blood gas determination and calculation of shunts in nonhemodynamic pulmonary edemas]. Qs/Qt is usually determined by the "oxygen" method. The standard equation for calculation of percentage shunts is therefore: (see article) In the case for an FiO2 of I and when PaO2 is greater than 150 mm Hg, the equation can be exp... | [
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PMID:9859 | [Continuous measurement, using 2 isotopes, of extravascular pulmonary water. Application of a new method or the analysis of supply and pulmonary capillary filtration in normal man]. | Measurement of pulmonary interstitial fluid may be useful in clinical medicine for early diagnosis or measurement of interstitial and/or alveolar pulmonary edema. A modification of the double dilution method of CHINARD and GORESKY is proposed. Compared to previous methods, this technique, using two isotopes gamma emit... | [Continuous measurement, using 2 isotopes, of extravascular pulmonary water. Application of a new method or the analysis of supply and pulmonary capillary filtration in normal man]. Measurement of pulmonary interstitial fluid may be useful in clinical medicine for early diagnosis or measurement of interstitial and/or a... | [
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PMID:9860 | [Pulmonary water and thoracic impedance. Evaluation of a measurement technic]. | We measured transthoracic electrical impedance in 17 anesthetized and mechanically ventilated dogs with a four-electrode system. A current (5 KHZ, 50 mu A) is injected and detected at axillary levels. Transthoracic impedance was 67 +/- 14 ohms (S.D.) with insignificant shifts in control animals. Pulmonary edemas were i... | [Pulmonary water and thoracic impedance. Evaluation of a measurement technic]. We measured transthoracic electrical impedance in 17 anesthetized and mechanically ventilated dogs with a four-electrode system. A current (5 KHZ, 50 mu A) is injected and detected at axillary levels. Transthoracic impedance was 67 +/- 14 oh... | [
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PMID:9861 | [Regional distribution of pulmonary perfusion during fluid overload in man]. | The effects of a fluid vascular overload (Dextran 40,000, 10 p. 100, 44 +/- ml/kg/45 min) were studied in 9 normal subjects in the upright position. The following were found: an increase in pulmonary blood volume (+30 p. 100), and in extravascular pulmonary water (+ 70 p. 100), a significant fall in pulmonary complianc... | [Regional distribution of pulmonary perfusion during fluid overload in man]. The effects of a fluid vascular overload (Dextran 40,000, 10 p. 100, 44 +/- ml/kg/45 min) were studied in 9 normal subjects in the upright position. The following were found: an increase in pulmonary blood volume (+30 p. 100), and in extravasc... | [
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PMID:9862 | [Pulmonary edemas. Anatomic study]. | Whatever the etiology of pulmonary edema, i.e. increase in intrapulmonary water, edema passes through three, moreover intricate phases: 1- intracellular edema clearly visible in the type 1 pneumocyte. This intracellular edema appears at the same time as: 2- interstitial edema; that which appears when: 3- numerous vesic... | [Pulmonary edemas. Anatomic study]. Whatever the etiology of pulmonary edema, i.e. increase in intrapulmonary water, edema passes through three, moreover intricate phases: 1- intracellular edema clearly visible in the type 1 pneumocyte. This intracellular edema appears at the same time as: 2- interstitial edema; that w... | [
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PMID:9863 | [Contribution of radiology in nonhemodynamic pulmonary edemas]. | The radiological appearances of non-hemodynamic, lesional edema are univoco; interstitial-type pictures, alveolar-type pictures, either successively or combined, in terms of the intensity or duration of the alveolo-capillary membrane lesions. Inflation of the interstitial medium is reflected by the appearance of Kerley... | [Contribution of radiology in nonhemodynamic pulmonary edemas]. The radiological appearances of non-hemodynamic, lesional edema are univoco; interstitial-type pictures, alveolar-type pictures, either successively or combined, in terms of the intensity or duration of the alveolo-capillary membrane lesions. Inflation of ... | [
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PMID:9864 | [Severity factors and diagnosis of nonhemodynamic pulmonary edemas]. | This syndrome is characterised by changes in the pulmonary capillary bed allowing filtration of edema fluid rich in proteins. It provokes an alveolo-capillary block and a fall in compliance. Positive diagnosis is envisaged from the clinical circumstances implicating a change in the pulmonary capillaries (blast, shock, ... | [Severity factors and diagnosis of nonhemodynamic pulmonary edemas]. This syndrome is characterised by changes in the pulmonary capillary bed allowing filtration of edema fluid rich in proteins. It provokes an alveolo-capillary block and a fall in compliance. Positive diagnosis is envisaged from the clinical circumstan... | [
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PMID:9865 | [Reduction and anti-inflammatory technics in non-hemodynamic pulmonary edemas]. | All hypervolemia or any decrease in plasma oncotic pressure leads to deterioration in lesional pulmonary edema. The aim of albumin infusions is to restore the plasma oncotic pressure and to oppose the passage of water into the extravascular space. This therapy is however debatable owing to the abnormal increase in the ... | [Reduction and anti-inflammatory technics in non-hemodynamic pulmonary edemas]. All hypervolemia or any decrease in plasma oncotic pressure leads to deterioration in lesional pulmonary edema. The aim of albumin infusions is to restore the plasma oncotic pressure and to oppose the passage of water into the extravascular... | [
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PMID:9866 | [Justification, methods and indications for positive-pressure respiration in controlled and spontaneous ventilation in lesional pulmonary edeman]. | Proposed since 1938 as a treatment for pulmonary edema, continuous positive pressure ventilation (PPP) still called teleexpiratory positive pressure in France (PPTE) and "Positive End Expiratory Pressure" (PEEP) or even "Continuous Pressure Breathing" (CPPB) in Anglo-Saxon countries, has taken a place in the first li... | [Justification, methods and indications for positive-pressure respiration in controlled and spontaneous ventilation in lesional pulmonary edeman]. Proposed since 1938 as a treatment for pulmonary edema, continuous positive pressure ventilation (PPP) still called teleexpiratory positive pressure in France (PPTE) and "P... | [
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PMID:9867 | [Treatment of fulminating lesional edemas using extracorporeal circulation with a membrane oxygenator]. | Recourse to extra-corporeal oxygenation is legitimate in certain cases of fulminating pulmonary edema, with refractory hypoxemia, particularly when the early onset of the hemodynamic condition and the severity of the hypoxemia do not permit the carrying out of dehydration. Veno-arterial diversion then permits: --the en... | [Treatment of fulminating lesional edemas using extracorporeal circulation with a membrane oxygenator]. Recourse to extra-corporeal oxygenation is legitimate in certain cases of fulminating pulmonary edema, with refractory hypoxemia, particularly when the early onset of the hemodynamic condition and the severity of the... | [
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PMID:9868 | [Present statues of lung transplantation (author's transl)]. | It is difficult to sum up the justifications for pulmonary transplantation in man as out of 34 cases carried out up to now only the patient DEROM, has survived 10 months. In fact, analysis shows that all of the other cases cannot be taken into consideration, as there were technical problems, or the receivers were nearl... | [Present statues of lung transplantation (author's transl)]. It is difficult to sum up the justifications for pulmonary transplantation in man as out of 34 cases carried out up to now only the patient DEROM, has survived 10 months. In fact, analysis shows that all of the other cases cannot be taken into consideration, ... | [
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PMID:9869 | [Vaso-active substances and pulmonary circulation]. | This study reveals the main vaso-active substances which pass through the lung, by studying in each case the extra-pulmonary of pulmonary origin, the effects of the lung on these substances: capture, discharge, transformation, and the effects of these substances on the lung. Eight groups of substances are studied: medi... | [Vaso-active substances and pulmonary circulation]. This study reveals the main vaso-active substances which pass through the lung, by studying in each case the extra-pulmonary of pulmonary origin, the effects of the lung on these substances: capture, discharge, transformation, and the effects of these substances on th... | [
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PMID:9870 | [Pulmonary edema due to shock, fat embolism, disseminated intravascular coagulation and post extracorporeal circulation]. | The appearance of lesional edema in the region of the alveolar wall constitues the initial phenomenon of involvement of the pulmonary parenchyma during shock lung, fat embolism, DIC and post perfusion lung syndrome. The alveolar septum reacts in a monomorphous manner to these various agressions, although the responsibl... | [Pulmonary edema due to shock, fat embolism, disseminated intravascular coagulation and post extracorporeal circulation]. The appearance of lesional edema in the region of the alveolar wall constitues the initial phenomenon of involvement of the pulmonary parenchyma during shock lung, fat embolism, DIC and post perfusi... | [
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PMID:9871 | [Pulmonary surfactants. Generalities]. | The alveolar wall on contact with air can be compared with a biological air-liquide interface. As with all interfaces, there are therefore superficial forces which tend to reduce the surface to a minimum. In the case of a pulmonary alveolus with a spherical surface, these forces are at the origin of an internal pressur... | [Pulmonary surfactants. Generalities]. The alveolar wall on contact with air can be compared with a biological air-liquide interface. As with all interfaces, there are therefore superficial forces which tend to reduce the surface to a minimum. In the case of a pulmonary alveolus with a spherical surface, these forces a... | [
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PMID:9872 | [Acute neurogenic pulmonary edema]. | Neurogenic edema, in the strict sense of the term, has at the present time practically not benefitted from precise hemodynamic investigations in human clinical practice, and owing to this fact, authors still classify them under the heading "mixed edema or of unknown pathogenesis". In contrast with this lack of informat... | [Acute neurogenic pulmonary edema]. Neurogenic edema, in the strict sense of the term, has at the present time practically not benefitted from precise hemodynamic investigations in human clinical practice, and owing to this fact, authors still classify them under the heading "mixed edema or of unknown pathogenesis". In... | [
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PMID:9873 | [Pulmonary edema in hangings]. | The authors present two cases of unsuccessful hanging which hat lead to a very severe neurological picture and especially the very rapid appearance of acute pulmonary edema resulting in a vertiable flooding of the alveoli. The victims, aged respectively 21 and 15 years, were free from any pre-existing cardiopathy. Thes... | [Pulmonary edema in hangings]. The authors present two cases of unsuccessful hanging which hat lead to a very severe neurological picture and especially the very rapid appearance of acute pulmonary edema resulting in a vertiable flooding of the alveoli. The victims, aged respectively 21 and 15 years, were free from any... | [
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PMID:9874 | [Nonhemodynamic pulmonary edema due to toxins]. | Lesional pulmonary edema caused by substances which are directly caustic for the gastrointestinal pathways (strong acids and bases, inhaled vomit) are opposed by their immediate and long-term gravity with those due to cardiotropic medicamentatous toxins or volemic overloading which lead to curable pulmonary edema. Mate... | [Nonhemodynamic pulmonary edema due to toxins]. Lesional pulmonary edema caused by substances which are directly caustic for the gastrointestinal pathways (strong acids and bases, inhaled vomit) are opposed by their immediate and long-term gravity with those due to cardiotropic medicamentatous toxins or volemic overloa... | [
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PMID:9875 | [Pulmonary edemas due to acute heroin poisoning]. | Their frequency is estimated with difficulty, although on autopsy pulmonary edema is found almost routinely. It is a major complication of overdoses (48 p. 100 of severe intoxications). Their formation can be suspected, when after the first phase of respiratory depressions, with coma, myosis, and a variable latent peri... | [Pulmonary edemas due to acute heroin poisoning]. Their frequency is estimated with difficulty, although on autopsy pulmonary edema is found almost routinely. It is a major complication of overdoses (48 p. 100 of severe intoxications). Their formation can be suspected, when after the first phase of respiratory depressi... | [
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PMID:9876 | [Oxygen toxicity for pulmonary parenchyma. Ultrastructural study by electron microscopy. Physiopathologic data]. | The lungs of rats submitted to 24, 36, 48 and 72 hours of pure normobaric oxygen were examined by means of the scanning microscope. The images obtained give a dynamic aspect of the changes in the lesions with two distinct phases: a phase of reactivity at 48 hours, marked by the development of hyperactivity of the granu... | [Oxygen toxicity for pulmonary parenchyma. Ultrastructural study by electron microscopy. Physiopathologic data]. The lungs of rats submitted to 24, 36, 48 and 72 hours of pure normobaric oxygen were examined by means of the scanning microscope. The images obtained give a dynamic aspect of the changes in the lesions wit... | [
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PMID:9877 | [Pulmonary edema due to inhalation of gas and vapors]. | In 1975, France will have manufactured 3.2 million tons of plastic materials which by pyrolysis, liberate chlorine, methyl chloride, hydrocyanic acid, hydrofluoric acid and other toxic gases. Now these materials are burnt in fires in "modern", buildings or vehicles , associated with fats (acrolein) and other gases and ... | [Pulmonary edema due to inhalation of gas and vapors]. In 1975, France will have manufactured 3.2 million tons of plastic materials which by pyrolysis, liberate chlorine, methyl chloride, hydrocyanic acid, hydrofluoric acid and other toxic gases. Now these materials are burnt in fires in "modern", buildings or vehicles... | [
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PMID:9878 | [Classification of corticoids]. | A pharmacological classification of corticoids can be carried out, based on the ratio of their glucocorticoid and mineralocorticoid activities. Their large number is due to the fact that they are practically all synthetic, and that minimal modifications in their structure gives rise to new drugs with variable gluco and... | [Classification of corticoids]. A pharmacological classification of corticoids can be carried out, based on the ratio of their glucocorticoid and mineralocorticoid activities. Their large number is due to the fact that they are practically all synthetic, and that minimal modifications in their structure gives rise to n... | [
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PMID:9879 | [Glucocorticoids and metabolism]. | After a brief historical account, the physiological effect of glucocorticoid hormones are analysed. Their main point of impact is neoglucogenesis from proteins. To this is added their direct action on carbohydrates, their intervention in the use of lipids, and in the movement of water and salts. Cortisone penetrates in... | [Glucocorticoids and metabolism]. After a brief historical account, the physiological effect of glucocorticoid hormones are analysed. Their main point of impact is neoglucogenesis from proteins. To this is added their direct action on carbohydrates, their intervention in the use of lipids, and in the movement of water ... | [
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PMID:9880 | [Study of carbohydrate tolerance without and with corticotherapy]. | Using the glucose tolerance test by the intravenous route, from which the coefficients K (CONARD) of carbohydrate assimilation and (BERNIER) of fasting glycogenolysis, are deduced, the authors study the carbohydrate tolerance of neuro-surgical patients in acute and chronic phases, under corticosteroid therapy and witho... | [Study of carbohydrate tolerance without and with corticotherapy]. Using the glucose tolerance test by the intravenous route, from which the coefficients K (CONARD) of carbohydrate assimilation and (BERNIER) of fasting glycogenolysis, are deduced, the authors study the carbohydrate tolerance of neuro-surgical patients ... | [
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PMID:9881 | [Corticoids in respiratory pathology]. | After briefly recalling the action of corticosteroids on the normal and pathological lung, the authors review the different etiologies where they can be used in respiratory pathology. | [Corticoids in respiratory pathology]. After briefly recalling the action of corticosteroids on the normal and pathological lung, the authors review the different etiologies where they can be used in respiratory pathology. | [
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PMID:9882 | [Immunological aspects of corticotherapy]. | The therapeutic effectiveness of corticoids in transplantation, in autoimmune conditions and in numerous diseases in which the pathogenic role of hypersensitivity reactions is invoked, is perfectly established on the empirical basis of clinical cases. The study of the effects of corticoids on the immunological response... | [Immunological aspects of corticotherapy]. The therapeutic effectiveness of corticoids in transplantation, in autoimmune conditions and in numerous diseases in which the pathogenic role of hypersensitivity reactions is invoked, is perfectly established on the empirical basis of clinical cases. The study of the effects ... | [
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PMID:9883 | [Hemodynamic effects of high-dosage corticoids. Their justification in the treatment of shock]. | In 61 patients in whom high doses of corticoids had been administered owing to various indications, the hemodynamic modifications caused by this injection were studied. The corticoids administered were : hydrocortisone hemisucccinate (150 mg/kg), methyl prednisolone sulfate (30 mg/kg), prednisone sodium m sulfobenzoate... | [Hemodynamic effects of high-dosage corticoids. Their justification in the treatment of shock]. In 61 patients in whom high doses of corticoids had been administered owing to various indications, the hemodynamic modifications caused by this injection were studied. The corticoids administered were : hydrocortisone hemis... | [
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PMID:9884 | [Corticoids and shock]. | After recalling the major role of catecholamines in the genesis of irreversible shock, the anti-shock action of glucocorticosteroids, owing to properties which are "alpha-blocking" , is discussed in this work. The works of LILLEHEI on the effectiveness of corticosteroids in different types of shock are summarized and d... | [Corticoids and shock]. After recalling the major role of catecholamines in the genesis of irreversible shock, the anti-shock action of glucocorticosteroids, owing to properties which are "alpha-blocking" , is discussed in this work. The works of LILLEHEI on the effectiveness of corticosteroids in different types of sh... | [
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PMID:9885 | [Corticosteroids and septic shock]. | According to the data in the literature, the authors attempted to sum-up present attitudes on the value of corticoids in the treatment of septic shock. If their cardiovascular effects after a period of enthusiasm, are presently rather controversial, their cellular and sub-cellular actions, on the lysosomal membranes, c... | [Corticosteroids and septic shock]. According to the data in the literature, the authors attempted to sum-up present attitudes on the value of corticoids in the treatment of septic shock. If their cardiovascular effects after a period of enthusiasm, are presently rather controversial, their cellular and sub-cellular ac... | [
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PMID:9886 | [Plasma cortisol in neurosurgical resuscitation]. | The authors study the values of spontaneous cortisonemia in neuro-surgical patients. They analysed the correlations between this parameter and certain clinical criteria (age, etiology, level of consciousness), the duration and nyctohemeral changes in spontaneous hypercortisonism. Furthermore, they presented the values ... | [Plasma cortisol in neurosurgical resuscitation]. The authors study the values of spontaneous cortisonemia in neuro-surgical patients. They analysed the correlations between this parameter and certain clinical criteria (age, etiology, level of consciousness), the duration and nyctohemeral changes in spontaneous hyperco... | [
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PMID:9887 | [Indications for anti-inflammatory corticoids in anesthesia-resuscitiation]. | The use of anti-inflammatory corticoids in anesthesia and resuscitation is a long-standing fact, but their indications, owing to the risks to which they expose certain patients and owing to the uncertitude concerning their mechanism of action, are still badly defined. If certain indications (attacks of asthma, laryngea... | [Indications for anti-inflammatory corticoids in anesthesia-resuscitiation]. The use of anti-inflammatory corticoids in anesthesia and resuscitation is a long-standing fact, but their indications, owing to the risks to which they expose certain patients and owing to the uncertitude concerning their mechanism of action,... | [
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PMID:9888 | [Complications and contraindications of corticotherapy]. | In a review of the classical complications of corticotherapy the aouthors tried, in the light of the literature, to take into consideration the ideas received as compared with the numerical conclusions of statistical studies on large series. Then they presented the patient treated with corticoids, faced with the surgic... | [Complications and contraindications of corticotherapy]. In a review of the classical complications of corticotherapy the aouthors tried, in the light of the literature, to take into consideration the ideas received as compared with the numerical conclusions of statistical studies on large series. Then they presented t... | [
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PMID:9889 | [Problems posed by surgical patients submitted to long-term corticotherapy]. | Contrary to the long-standing attitude which consisted of descreasing the doses of cortisone, or even of weaning patients before undergoing a surgical intervention, the author emphasizes the necessity for a quantitative and qualitative increase in corticotherapy in order to avoid the risks of acute hypocorti-costeroidi... | [Problems posed by surgical patients submitted to long-term corticotherapy]. Contrary to the long-standing attitude which consisted of descreasing the doses of cortisone, or even of weaning patients before undergoing a surgical intervention, the author emphasizes the necessity for a quantitative and qualitative increas... | [
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PMID:9890 | [Determination of phenobarbital, mephenytoin and diphenylhydantoin in the surveillance of anticonvulsant treatment]. | The authors describe a method of simultaneous estimation of phenobarbitone, mephenytoin and diphenylhydantoin in the blood. After extraction with ether, the methylation of these substances by trimethylanilinium hydroxide permits their rapid separation by gas chromatography. Heptabarbitone is used as internal standard a... | [Determination of phenobarbital, mephenytoin and diphenylhydantoin in the surveillance of anticonvulsant treatment]. The authors describe a method of simultaneous estimation of phenobarbitone, mephenytoin and diphenylhydantoin in the blood. After extraction with ether, the methylation of these substances by trimethylan... | [
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PMID:9891 | [Determination of isoniazid in blood plasma]. | The authors describe a new method of estimation of isoniazid in biological fluids, based on the formation and extraction of aluminium chelate obtained after combination of the isoniazid with salicylic aldehyde. The study of conditions of defecation and reaction permits one to eliminate interference with the metabolites... | [Determination of isoniazid in blood plasma]. The authors describe a new method of estimation of isoniazid in biological fluids, based on the formation and extraction of aluminium chelate obtained after combination of the isoniazid with salicylic aldehyde. The study of conditions of defecation and reaction permits one ... | [
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PMID:9893 | [Electrogastroenterographic study of the digestive motor effects of prolonged psychotropic treatment]. | Functional digestive complaints are frequent in psychiatri patients: simple constipation, which cannot be explained solely by the loss of the sensation of rectal fullness; occlusions, occasionally hemorragies; the late complication of dolichomegacolon (Bourgeois, 1973). In 160 subjects, an attempt to understand the phy... | [Electrogastroenterographic study of the digestive motor effects of prolonged psychotropic treatment]. Functional digestive complaints are frequent in psychiatri patients: simple constipation, which cannot be explained solely by the loss of the sensation of rectal fullness; occlusions, occasionally hemorragies; the lat... | [
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PMID:9898 | Effect of acid and salt concentration in fresh-pack pickles on the growth of Clostridium botulinum spores. | The addition of various amounts of acetic acid to pureed cucumbers inoculated with Clostridium botulinum spores has shown that outgrowth is inhibited at pH 4.8 but not at pH 5.0. Inoculation experiments with whole cucumbers showed that as little as 0.9% acetic acid in the brine was sufficient to prevent outgrowth from ... | Effect of acid and salt concentration in fresh-pack pickles on the growth of Clostridium botulinum spores. The addition of various amounts of acetic acid to pureed cucumbers inoculated with Clostridium botulinum spores has shown that outgrowth is inhibited at pH 4.8 but not at pH 5.0. Inoculation experiments with whole... | [
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PMID:9896 | [On the ecology of marine chromatiaceae and chlorobiaceae (author's transl)]. | Number and genera (types) of phototrophic red and green sulfur bacteria have been determined in the upper layer of eleven marine sediment samples from the euphotic zone in the Mediterranean Sea. Origin and nature of the sediment samples are given as well as their pH, total nitrogen and sulfide content. The results show... | [On the ecology of marine chromatiaceae and chlorobiaceae (author's transl)]. Number and genera (types) of phototrophic red and green sulfur bacteria have been determined in the upper layer of eleven marine sediment samples from the euphotic zone in the Mediterranean Sea. Origin and nature of the sediment samples are g... | [
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PMID:9899 | Isolation and characterization of an enzyme with esterase activity from Micropolyspora faeni. | The isolation and the characterization of one of the enzymes of Micropolyspora faeni that hydrolyzes the substrate N-benzoyl-DL-phenylalanine-beta-naphthyl ester and that seems to be of medical importance are described. This enzyme (enzyme 1) was isolated with an 86-fold purification by using the following seven steps:... | Isolation and characterization of an enzyme with esterase activity from Micropolyspora faeni. The isolation and the characterization of one of the enzymes of Micropolyspora faeni that hydrolyzes the substrate N-benzoyl-DL-phenylalanine-beta-naphthyl ester and that seems to be of medical importance are described. This e... | [
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PMID:9897 | Therapeutic drug monitoring: measurements of antiepileptic and barbiturate drug levels in blood by gas chromatography with nitrogen - selective detector. | The nitrogen-specific detector for gas chromatography consists of a non-volatile rubidium silicate bead, around which nitrogen-containing compounds are pyrolyzed. Speed, sensitivity, specificity, accuracy, small sample size and minumum sample handling are characteristics of the nitrogen detector that render it superior... | Therapeutic drug monitoring: measurements of antiepileptic and barbiturate drug levels in blood by gas chromatography with nitrogen - selective detector. The nitrogen-specific detector for gas chromatography consists of a non-volatile rubidium silicate bead, around which nitrogen-containing compounds are pyrolyzed. Spe... | [
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PMID:9900 | Oxidation of ethane by an Acremonium species. | Ethane oxidation was studied in ethane-grown resting cells (mycelia) of an Acremonium sp. and in cell-free preparations of such mycelia. From resting cell experiments evidence was found for a pathway of ethane oxidation via ethanol, acetaldehyde, and acetic acid. In vitro studies indicated that ethane-oxidizing activit... | Oxidation of ethane by an Acremonium species. Ethane oxidation was studied in ethane-grown resting cells (mycelia) of an Acremonium sp. and in cell-free preparations of such mycelia. From resting cell experiments evidence was found for a pathway of ethane oxidation via ethanol, acetaldehyde, and acetic acid. In vitro s... | [
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PMID:9901 | Enzymatic hydrolysis of organophosphate insecticides, a possible pesticide disposal method. | A crude cell extract from a mixed bacterial culture growing on parathion, an organophosphate insecticide, hydrolyzed parathion (21 C) at a rate of 416 nmol/min per mg of protein. This rate of enzymatic hydrolysis, when compared with chemical hydrolysis by 0.1 N sodium hydroxide at 40 C, was 2, 450 times faster. Eight o... | Enzymatic hydrolysis of organophosphate insecticides, a possible pesticide disposal method. A crude cell extract from a mixed bacterial culture growing on parathion, an organophosphate insecticide, hydrolyzed parathion (21 C) at a rate of 416 nmol/min per mg of protein. This rate of enzymatic hydrolysis, when compared ... | [
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0.01... |
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