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2,320,500 | [Usefulness of the "P.N." frame in biopsies and stereotactic operations on the brain]. | Stereotactic biopsy represents the gold standard for tissue diagnosis surgically inaccessible gliomas, tumors and cystic lesions. Tissue samples can be obtained by minimally invasive technique. Moreover, the combination of the neuro-endoscope with stereotactic method is possible.</AbstractText>23 patients underwent 43 ... |
2,320,501 | Modulation of spontaneous electrical activity of freshly isolated 3-day embryonic chick ventricle by cAMP and cGMP. | Effects of cyclic nucleotides 8-Bromo-cAMP and 8-Bromo-cGMP (membrane permeable analogs of cAMP and cGMP) were examined on action potential (AP) configuration and rate of spontaneous firing of the freshly isolated 3-day embryonic chick ventricle (ECV) to assess the role of L-type slow Ca2+ channels in upstroke of AP an... |
2,320,502 | Intraventricular neurocytoma with massive brain stem involvement in a 5-year-old child. | Central neurocytoma is a tumor of neuronal origin that should be taken into consideration in the differential diagnosis of intraventricular neoplasms. Reports of neurocytomas with an extraventricular localization are rare: to our knowledge, the case described here is the first in which a neurocytoma developed within th... |
2,320,503 | Endoscopic aqueductal stenting via the fourth ventricle under navigating system guidance: technical note. | We report three patients with symptomatic isolated fourth ventricle after ventriculoperitoneal shunt placement for hydrocephalus associated with ventricular hemorrhage. All three patients were treated successfully with our new method of endoscopic aqueductal stenting under navigating system guidance.</AbstractText>A th... |
2,320,504 | Microsurgical removal of intraventricular lesions using endoscopic visualization and stereotactic guidance. | To demonstrate the technique of stereotactic microsurgical endoscopic removal of intraventricular tumors or colloid cysts assisted by intraoperative computed tomography.</AbstractText>We adapted a tubular "ventriculoport" for stereotactic insertion of an endoscope into the ventricle. This facilitated microsurgical rese... |
2,320,505 | Lateral ventricle tumors: surgical strategies according to tumor origin and development--a series of 72 cases. | Optimal surgical management in lateral ventricle tumors remains controversial. We conducted a retrospective study of patients with these lesions treated with a surgical strategy on the basis of tumor origin: primary or secondary ventricular and associated transependymal development.</AbstractText>A total of 72 patients... |
2,320,506 | Supratentorial intraventricular schwannoma. | A rare case of supratentorial intraventricular schwannoma is described. A 16-year-old male with asymptomatic papilloedema was found to have a 5-cm intraventricular tumour arising from the trigone of the right lateral ventricle. A craniotomy and total macroscopic excision was performed. |
2,320,507 | Calculation of left ventricle relative pressure distribution in MRI using acceleration data. | Measurements of pressure variations within the cardiac chambers could provide important information for clinical assessments of cardiovascular function. In this work an MRI method for evaluating spatial distributions of intracardiac relative pressure is presented. We first calculated pressure gradients from MR maps of ... |
2,320,508 | Cerebrospinal fluid MR dynamics and risk of falls in the elderly. | To investigate the relationship between CSF dynamics and risk of falls of unknown origin in the elderly.</AbstractText>Phase contrast MR studies allowed CSF aqueductal flow quantification on 23 community-dwelling older people initially explored for mild cognitive impairment. Mobility assessment included report of falls... |
2,320,509 | Heterotypic neuronal differentiation of adult subependymal zone neuronal progenitor cells transplanted to the adult hippocampus. | Neuronal progenitor cells (NPCs) residing in the adult subependymal zone (SEZ) are a potential source of expandable cells for autologous transplantation to replace neurons lost in multiple types of brain injury. To characterize the capacity of these cells for neuronal differentiation in a mature ectopic environment, NP... |
2,320,510 | Distribution of corticotropin-releasing factor binding protein-immunoreactivity in the rat hypothalamus: association with corticotropin-releasing factor-, urocortin 1- and vimentin-immunoreactive fibres. | Corticotropin-releasing factor binding protein (CRF-BP) is a 37-kDa protein with high affinity binding sites for both corticotropin-releasing factor (CRF) and urocortin 1. Previous studies have examined the distribution of CRF-BP mRNA and peptide within the central nervous system. Due to the predominant cortical locali... |
2,320,511 | Male and female prolactin receptor mRNA expression in the brain of a biparental and a uniparental hamster, phodopus, before and after the birth of a litter. | Prolactin receptor (PRL-R) mRNA transcript level was quantified in the choroid plexus (ChP) of a naturally biparental hamster, Phodopus campbelli, and its otherwise similar, yet nonpaternal, sibling species, Phodopus sungorus. Pair-housed males and females on the day before the birth of their first litter (G17), the da... |
2,320,512 | Design-based stereological estimation of the total number of cardiac myocytes in histological sections. | Counting the total number of cardiac myocytes has not previously been possible in ordinary histological sections using light microscopy (LM) due to difficulties in defining the myocyte borders properly.</AbstractText>To describe a method by which the total number of cardiac myocytes is estimated in LM sections using de... |
2,320,513 | A longitudinal study of brain morphometrics using serial magnetic resonance imaging analysis in a canine model of aging. | Longitudinal changes in cortical atrophy, ventricular enlargement, and lesion development in serial MRI scans collected from 47 healthy dogs from 1999 (8-11 years old) to 2002 (11-14 years old) were studied. The first method involved manual region of interest volumetric analysis to examine changes in cerebral and ventr... |
2,320,514 | Acute third ventricular administration of leptin decreases protein and fat in self-selecting rats. | The peripheral administration of leptin reduces food intake (FI) body weight gain (BWG) and modifies food choice. The aim of this study was to examine the effect of acute cerebral injections of leptin on food selection in rats. Male rats were first adapted to the food choice paradigm (protein, carbohydrate, fat) for 3 ... |
2,320,515 | Lateral transsulcal approach to asymptomatic trigonal meningiomas with correlative microsurgical anatomy: technical case report. | We introduce the lateral transsulcal approach to asymptomatic trigonal meningiomas.</AbstractText>The approach was studied in two cadaver brains and three asymptomatic patients with trigonal meningiomas. The posterior part of the sylvian fissure, or superior temporal sulcus, is opened to the bottom. Through a small hor... |
2,320,516 | Intuitive intraoperative ultrasound guidance using the Sonic Flashlight: a novel ultrasound display system. | The Sonic Flashlight (SF) is a new handheld ultrasound (US) display device being developed at our institution. It replaces the standard monitor on a conventional ultrasound (CUS) system with a miniature monitor and half-silvered mirror to reflect real-time US images into the body. With the SF, the imaged body part appe... |
2,320,517 | Microsurgical anatomy of the transcallosal anterior interforniceal approach to the third ventricle. | We explored relevant regional microanatomy as it relates to the challenging anterior interforniceal (AIF) approach for removing hypothalamic hamartomas.</AbstractText>Five silicone-injected cadaveric heads were dissected by use of frameless stereotactic navigation to reveal microanatomy and extent of exposure through t... |
2,320,518 | Severe epilepsy and pachygyria associated with peculiar facial traits characterize Fryns-Aftimos syndrome. | We describe an 18-year-old boy with a frontofacial syndrome. The presence of severe epilepsy led to a neuroimaging investigation, which revealed a diffuse pachygyric (normal thickness and simplified folding) cortex that was bilateral and affected all supratentorial regions, sparing the medial and inferior aspects of th... |
2,320,519 | Intramedullary ectopic choroid plexus: report of a rare case. | Intracranial cysts containing an ectopic choroid plexus or choroid plexus-like tissue have seldom been described in the literature. However, there has been no report of a spinal intramedullary cyst containing an ectopic choroid plexus. This is the first case report in the available literature of an ectopic choroid plex... |
2,320,520 | Effect of interleukin-1beta on the variation of adenylyl cyclase expression in rats with seizures induced by L-glutamate. | To explore the mechanism of interleukin-1beta (IL-1beta) in the onset of seizure and the effect of IL-1beta on the expression of adenylyl cyclase (AC) in rats with seizure induced by L-glutamate. Experimental rats were first injected with IL-1beta and then L-glutamate (a dose under the threshold) was injected into the ... |
2,320,521 | Fetal cerebral ventriculomegaly: outcome in 176 cases. | To evaluate the outcome of fetuses affected by different degrees of ventriculomegaly.</AbstractText>We studied 176 fetuses with ventriculomegaly and evaluated the pregnancy outcome and the neurodevelopmental outcome at age > or = 24 months. The population was divided into three groups according to ventricular width:... |
2,320,522 | Isolated diastasis of cranial sutures: unusual presentation of a blocked shunt in an infant. | Ventriculo-peritoneal (VP) shunt malfunction is usually due to blockage of the ventricular catheter and this is typically apparent as enlarged ventricles on a CT scan of the brain. We describe a less common radiological finding in an infant with a blocked shunt.</AbstractText>A male infant presenting with hydrocephalus... |
2,320,523 | Clinically silent choroid plexus cyst: evaluation by diffusion-weighted MRI. | We retrospectively reviewed diffusion-weighted magnetic resonance images of 57 patients with a choroid plexus cyst diagnosed by contrast-enhanced T1-weighted imaging. All the cysts appeared to represent incidental findings. Thirty-eight of 57 patients had bilateral cysts and 19 had unilateral ones. On diffusion-weighte... |
2,320,524 | The effects of early lead exposure on the brains of adult rhesus monkeys: a volumetric MRI study. | Little is known about direct effects of exposure to lead on central nervous system development. We conducted volumetric MRI studies in three groups of 17-year-old rhesus monkeys: (1) a group exposed to lead throughout gestation (n = 3), (2) a group exposed to lead through breast milk from birth to weaning (n = 4), and ... |
2,320,525 | Functional anatomy of motor recovery after early brain damage. | Functional magnetic resonance imaging and transcranial magnetic stimulation were used to examine a 34 year-old right-handed patient, who, at the age of 6 years, had experienced sudden right hemiplegia, seizures, and stupor during a bout of measles encephalitis, followed by incomplete distal right motor recovery. Morpho... |
2,320,526 | [Effect of some imidazole-4,5-dicarboxylic acid derivatives on the activity of N-methyl-D-aspartate (NMDA) receptors].<Pagination><StartPage>7</StartPage><EndPage>9</EndPage><MedlinePgn>7-9</MedlinePgn></Pagination><Abstract><AbstractText>The results of experiments on mice showed that some imidazole-4,5-dicarboxylic ac... | The results of experiments on mice showed that some imidazole-4,5-dicarboxylic acid derivatives injected into lateral cerebral ventricles produce a dose-dependent convulsant or anticonvulsant effects, that is, possess the properties of partial NMDA receptor agonists. The most promising partial NMDA receptor agonist sel... |
2,320,527 | Frontal and temporal morphometric findings on MRI in children after moderate to severe traumatic brain injury. | In vivo MRI volumetric analysis enables investigators to evaluate the extent of tissue loss following traumatic brain injury (TBI). However, volumetric studies of pediatric TBI are sparse, and there have been no volumetric studies to date in children examining specific subregions of the prefrontal and temporal lobes. I... |
2,320,528 | Transfer of morphine along the olfactory pathway to the central nervous system after nasal administration to rodents. | The aim of this study was to investigate whether morphine can be transferred along the olfactory pathway to the CNS, thereby circumventing the blood-brain barrier, after nasal administration to rodents. Radiolabelled and unlabelled morphine were administered via the right nostril to mice and rats. Olfactory bulbs, brai... |
2,320,529 | [Prolonged cerebral salt wasting following craniopharyngioma surgery and posterior reversible encephalopathy syndrome: a case report]. | A 9-year-old boy was admitted to our hospital with daytime urinary incontinence for the past one year. MRI showed craniopharyngioma occupying the third ventricle. The tumor was excised by interhemispheric approach. Because hyponatremia and polyuria with high renal loss of sodium were observed on postoperative day 3, hy... |
2,320,530 | [Medulloblastoma with mandibular metastasis after complete remission of the central nervous system lesions]. | A 6-year-old boy presented with headache and vomiting. Brain and spinal MRI demonstrated a large mass in the cerebellar vermis and 4th ventricle and showed thick spinal subarachnoid dissemination. Suboccipital craniotomy was performed and the tumor was totally removed. The histological diagnosis was medulloblastoma. Th... |
2,320,531 | Diagnostic challenge of fetal ontogeny and its application on the ovarian teratomas. | Although neuroepithelial tubules (NET) often are a component of immature teratoma (IT), they are not always required for diagnosis. Other somatic elements are sufficient and often verified with immunohistochemical stain. This study was designed to determine the definition of immaturity versus fetal ontogeny, using seve... |
2,320,532 | Spinal tanycytic ependymoma with hematomyelia--case report--. | A 58-year-old man presented with an extremely rare case of "pure type" spinal tanycytic ependymoma associated with hematomyelia manifesting as sensory disturbance of the bilateral hands and weakness of the right arm. Magnetic resonance imaging demonstrated a tumor in the spinal cord from C-2 to C-4 levels. The soft gel... |
2,320,533 | Hippocampal and ventricular volumes in psychotic and nonpsychotic bipolar patients compared with schizophrenia patients and community control subjects: a pilot study. | Previous reports of ventricular and hippocampal volumes in patients with bipolar disorder (BP) have been inconsistent in their findings. One possibility is that volumetric abnormalities are determined by disease subtype. Prior evidence suggests that psychotic (PBP) and nonpsychotic (NPBP) forms of BP are two subtypes t... |
2,320,534 | Ventriculitis due to a hetero strain of vancomycin intermediate Staphylococcus aureus (hVISA): successful treatment with linezolid in combination with intraventricular vancomycin. | A 67-year male presented with relapse 14 days after treatment with vancomycin for a MRSA ventriculitis. CSF samples taken at the time of relapse grew MRSA with a MIC for vancomycin of 4 mg/L by E-test and therapy with linezolid (600 mg bd) and intraventricular vancomycin (20 mg od) was initiated. Using the macrodilutio... |
2,320,535 | In vivo measurements of T1 relaxation times in mouse brain associated with different modes of systemic administration of manganese chloride. | To measure regional T1 and T2 values for normal C57Bl/6 mouse brain and changes in T1 after systemic administration of manganese chloride (MnCl2) at 9.4 T.</AbstractText>C57Bl/6 mice were anesthetized and baseline T1 and T2 measurements obtained prior to measurement of T1 after administration of MnCl2 at 9.4 T. MnCl2 w... |
2,320,536 | [Commissural agenesis associated with inter hemispheric cyst]. | The Objectives of this study were to Report a rare malformation and to try to understand the embryological origin of such lesion. We reported the case of an eight-month-old female infant, without any particular past medical history, who was refered for seizures and vomiting. The examination revealed normal anthropometr... |
2,320,537 | [Growing skull fracture with cerebral and ventricular hernia after brain trauma]. | Authors report the case of 3 years old boy. He represented a severe head injury with dura mater damage and skull fracture. He has been operated and few years later, he present a vault tumefaction. CT scan show a very large bone defect, a cerebral and ventricular hernia. Mecanism and causal factors are discussed. |
2,320,538 | [Analysis of Na+/Ca2+ exchanger knockout mice]. | The Na(+)/Ca(2+) exchanger (NCX) on the plasma membrane is thought to be the main calcium extrusion system from the cytosol to the extracellular space in many mammalian excitable cells including cardiac myocytes. However, the precise roles of NCX are still unclear because of lack of its specific inhibitors. We generate... |
2,320,539 | Morphometric analysis of lateral ventricles in schizophrenia and healthy controls regarding genetic and disease-specific factors. | The structural variability of lateral ventricles is poorly understood notwithstanding that enlarged size has been identified as an unspecific marker for psychiatric illness, including schizophrenia. This paper explores the effects of heritability and genetic risk for schizophrenia reflected in ventricular size and stru... |
2,320,540 | Gap junctional remodeling by hypoxia in cultured neonatal rat ventricular myocytes. | Altered gap junctional coupling of ventricular myocytes plays an important role in arrhythmogenesis in ischemic heart disease. Since hypoxia is a major component of ischemia, we tested the hypothesis that hypoxia causes gap junctional remodeling accompanied by conduction disturbances.</AbstractText>Cultured neonatal ra... |
2,320,541 | Anoxic versus traumatic brain injury: amount of tissue loss, not etiology, alters cognitive and emotional function. | Research in neuropsychology suggests that the etiology of a neurologic injury determines the neuropathological and neuropsychological changes. This study compared neuropsychological outcome in subjects who had traumatic brain injury (TBI) with subjects who had anoxic brain injury (ABI), who were matched for age, gender... |
2,320,542 | Primary hyperoxaluria type-1: an unprecedented presentation at birth. | This report describes a male baby with primary hyperoxaluria type-1, presenting at 5 hours of age with cyanotic episodes, hypotonia, unexplained techypnea and tachycardia. This infant also had renal calcinosis, and middle cerebral arterial infarct with unilateral enlargement of ventricle and left porencephalic cyst on ... |
2,320,543 | Primary amyloidoma of the brain parenchyma. | Amyloidoma can occur within the brain parenchyma. Periventricular amyloidomas developed in a man aged 69 years as gadolinium-enhancing lesions on magnetic resonance imaging. The lesions were composed of amyloid AL lambda with congophilia resistant to potassium permanganate. There was no evidence of systemic amyloidosis... |
2,320,544 | Effects of intracerebroventricular infusion of genistein on the secretory activity of the GnRH/LH axis in ovariectomized ewes. | Phytoestrogens, plant derived estrogen like-compounds exert numerous effects on the reproductive functions of animals. The present study was designed to demonstrate if exogenous genistein infused during the breeding season into the third ventricle of the brain of ovariectomized ewes could affect the secretory activity ... |
2,320,545 | K+ currents activated by depolarization in cardiac fibroblasts. | K(+) currents expressed in freshly dispersed rat ventricular fibroblasts have been studied using whole-cell patch-clamp recordings. Depolarizing voltage steps from a holding potential of -90 mV activated time- and voltage-dependent outward currents at membrane potentials positive to approximately -30 mV. The relatively... |
2,320,546 | Expression of Cdv-iR gene in mouse epididymis as revealed by in situ hybridization. | We have previously studied mouse Cdv (carnitine deficiency-associated gene expressed in ventricle)-1 related gene Cdv-1IR and its human counterpart CDV-1R, and revealed that mouse Cdv-1R was predominantly expressed in testis by multiple tissue northern analysis. To further localize the Cdv-1R mRNA in mouse testis and e... |
2,320,547 | Developmental Vitamin D3 deficiency alters the adult rat brain. | There is growing evidence that Vitamin D(3) (1,25-dihydroxyvitamin D(3)) is involved in brain development. We have recently shown that the brains of newborn rats from Vitamin D(3) deficient dams were larger than controls, had increased cell proliferation, larger lateral ventricles, and reduced cortical thickness. Brain... |
2,320,548 | Cns tumors at AKU: an update plus a brief discussion on intraventricular tumors with special emphasis on central neurocytoma. | This paper is intended to be an update of our earlier published work on CNS tumors along with additional information on intraventricular tumors. Three cases of central neurocytoma are also discussed.</AbstractText>An analysis conducted in the Section of Histopathology, AKU to determine the frequency of all CNS neoplasm... |
2,320,549 | Cross-talk between the insulin and leptin signaling systems in rat hypothalamus. | To investigate whether insulin and leptin share common intracellular signal transduction pathways and to determine whether these hormonal signaling systems modulate each other's action in rat hypothalamus.</AbstractText>Male Wistar rats were studied after chronic implantation of an intracerebroventricular catheter into... |
2,320,550 | FLAIR diffusion-tensor MR tractography: comparison of fiber tracking with conventional imaging. | Partial volume with CSF is known to contaminate the quantification of white matter anisotropy depicted by diffusion tensor imaging (DTI). We hypothesized that the FLAIR technique helps to improve DTI white matter tractography in the normal adult brain by eliminating CSF partial volume effects.</AbstractText>Seven healt... |
2,320,551 | Computational modeling of cardiac ventricular action potentials in rat and mouse: review. | Little is known about the ionic mechanisms underlying the action potential heterogeneity in ventricle-associated healthy and disease conditions, even though five decades of histological, electrophysiological, pharmacological, and biochemical investigations exist. The computational modeling in murine ventricular myocyte... |
2,320,552 | Signaling within the master clock of the brain: localized activation of mitogen-activated protein kinase by gastrin-releasing peptide. | The circadian clock located in the mammalian suprachiasmatic nucleus (SCN) exhibits substantial heterogeneity in both its neurochemical and functional organization, with retinal input and oscillatory timekeeping functions segregated to different regions within the nucleus. Although it is clear that photic information m... |
2,320,553 | Initiation of embryonic cardiac pacemaker activity by inositol 1,4,5-trisphosphate-dependent calcium signaling. | In the adult, the heart rate is driven by spontaneous and repetitive depolarizations of pacemaker cells to generate a firing of action potentials propagating along the conduction system and spreading into the ventricles. In the early embryo before E9.5, the pacemaker ionic channel responsible for the spontaneous depola... |
2,320,554 | Central administration of transforming growth factor-alpha and neuregulin-1 suppress active behaviors and cause weight loss in hamsters. | Transforming growth factor-alpha (TGF-alpha) is a candidate output signal of the hypothalamic circadian pacemaker. TGF-alpha is expressed in the suprachiasmatic nucleus (SCN) of rats, hamsters, and rhesus macaques [A. Kramer, F.C. Yang, P. Snodgrass, X. Li, T.E. Scammell, F.C. Davis and C.J. Weitz, Regulation of daily ... |
2,320,555 | The distribution of neural nitric oxide synthase-positive cerebrospinal fluid-contacting neurons in the third ventricular wall of male rats and coexistence with vasopressin or oxytocin. | The detailed distribution of neural nitric oxide synthase (nNOS)-positive cerebrospinal fluid-contacting neurons (CSF-CN) was studied in the wall of the third ventricle of rats by anti-nNOS immunohistochemistry. The coexistence of nNOS and 8-arginine vasopressin (AVP) or oxytocin (OT) was also investigated in the CSF-C... |
2,320,556 | Hemangioblastoma of the lateral ventricle: case report and review of the literature. | We report a unique case of hemangioblastoma of the lateral ventricle in a 73 year-old man with cognitive deficits and fluent dysphasia. He harboured an intraventricular tumor, placed at the trigone of the left lateral ventricle. The tumor was successfully excised, by means of a temporal craniotomy. The patient became m... |
2,320,557 | D3 dopamine receptors do not regulate neurogenesis in the subventricular zone of adult mice. | Testing the effects of drugs that stimulate endogenous neurogenesis in different species is important for the development of neural repair strategies in humans. We have previously shown in adult rats that a 14-day intracerebroventricular infusion of the D3 preferential agonist 7-hydroxydipropyl-amino-tetraline (7-OH-DP... |
2,320,558 | Neurogenesis in the ependymal layer of the adult rat 3rd ventricle. | Neurogenesis has been described in limited regions of the adult mammalian brain. In this study, we showed that the ependymal layer of the 3rd ventricle is a neurogenic region in the adult rat brain. DiI labeling of the 3rd ventricle revealed that neural progenitor cells were derived from cells at the ependymal layer of... |
2,320,559 | Transient expression of MIDC-8 in the normal mouse brain. | In this study, we have immunohistochemically characterized the expression of mononuclear phagocyte markers CD14, CD36, CD68, CD204 and MARCO by parenchymal microglia in the developing and adult mouse brain. We further investigated whether these cells express two well-characterized phenotypic markers of dendritic cells:... |
2,320,560 | Magnetic storm effect on the circulation of rabbits. | The ultrastructure of cardiomyocytes of rabbits was found to be drastically altered at a time coinciding with strong magnetic storms by comparison with that usually observed during quiet geomagnetic conditions. The circadian characteristics of systolic and mean pressure in the left and right ventricles of Chinchilla ra... |
2,320,561 | Cranial manipulation can alter sleep latency and sympathetic nerve activity in humans: a pilot study. | To determine if cranial manipulation is associated with altered sleep latency. Furthermore, we investigated the effects of cranial manipulation on muscle sympathetic nerve activity (MSNA) as a potential mechanism for altered sleep latency.</AbstractText>Randomized block design with repeated measures.</AbstractText>The ... |
2,320,562 | Functional manipulations of acetylcholinesterase splice variants highlight alternative splicing contributions to murine neocortical development. | Proliferation and differentiation of mammalian central nervous system progenitor cells involve concertedly controlled transcriptional and alternative splicing modulations. Searching for the developmental implications of this programming, we manipulated specific acetylcholinesterase (AChE) splice variants in the embryon... |
2,320,563 | Obstetrical complications in gestational carrier pregnancies. | To report two cases of severe obstetrical complications in gestational carrier pregnancies and to review our clinical experience and compare our results with those reported in the literature.</AbstractText>Retrospective analysis.</AbstractText>A university IVF program.</AbstractText><AbstractText Label="PATIENT(S)" Nlm... |
2,320,564 | Serotonin 5-HT2C receptor-mediated phosphoinositide hydrolysis in rat choroid plexus after fluoxetine and citalopram treatments. | Selective serotonin reuptake inhibitors (SSRIs) bind directly to various neurotransmitter receptors. The clinical effects of SSRIs appear gradually during weeks of treatment, suggesting a role for adaptive changes in neurotransmitter receptors. Most clinically used antidepressants, e.g. fluoxetine, bind to 5-HT2C recep... |
2,320,565 | Aqueduct stenosis-?Benign. | 'Benign' aqueduct stenosis is a common cause of hydrocephalus in the paediatric population and is frequently treated by endoscopic third ventriculostomy. Occasionally, aqueduct stenosis can be a prelude to the development of other pathology, as is seen in these two cases of pineal tumours developing in patients whose h... |
2,320,566 | Characterization of chromanol 293B-induced block of the delayed-rectifier K+ current in heart-derived H9c2 cells. | The effects of chromanol 293B on ion currents in rat embryonic heart-derived H9c2 cells were investigated in this study. Chromanol 293B suppressed the amplitude of delayed rectified K+ current (I(K)) in a concentration-dependent manner. The IC50 value for chromanol 293B-induced inhibition of I(K) was 8 microM. The I(K)... |
2,320,567 | Endoscopic third ventriculostomy in post-tubercular meningitic hydrocephalus: a preliminary report. | Hydrocephalus is a common sequel of tubercular meningitis. Endoscopic third ventriculostomy (ETV) was performed in thirty-five patients. According to the duration of illness, six patients were in the early (less than 6 weeks), nineteen were in the intermediate (6 weeks to 6 months) and ten patients were in the late pha... |
2,320,568 | Brain stem melanocortinergic modulation of meal size and identification of hypothalamic POMC projections. | Metabolic, cognitive, and environmental factors processed in the forebrain modulate food intake by changing the potency of direct controls of meal ingestion in the brain stem. Here, we behaviorally and anatomically test the role of the hypothalamic proopiomelanocortin (POMC) system in mediating some of these descending... |
2,320,569 | Dual regulatory effects of orexins on sympathetic nerve activity innervating brown adipose tissue in rats. | This study examined how orexin regulates the activity of the sympathetic nerves that innervate brown adipose tissue (BAT) in rats. Infusion of orexin A at a dose of 0.3 nmol into the third cerebral ventricle decreased BAT sympathetic nerve activity, compared with the effect of PBS (P < 0.05), whereas infusion of ore... |
2,320,570 | Manganese acts centrally to stimulate luteinizing hormone secretion: a potential influence on female pubertal development. | Manganese (Mn), an essential element considered important for normal growth and reproduction, has been shown in adults to be detrimental to reproductive function when elevated. Because Mn can cross the blood-brain barrier and accumulate in the hypothalamus, and because it has been suggested that infants and children ar... |
2,320,571 | Coxsackievirus targets proliferating neuronal progenitor cells in the neonatal CNS. | Type B coxsackieviruses (CVB) frequently infect the CNS and, together with other enteroviruses, are the most common cause of viral meningitis in humans. Newborn infants are particularly vulnerable, and CVB also can infect the fetus, leading to mortality, or to neurodevelopmental defects in surviving infants. Using a mo... |
2,320,572 | Cardiac Aspergillosis with pedunculated mass in the left ventricle. | Immunosuppression can allow organisms that are not usually pathogenetic to cause disease; under such circumstances, Aspergillus species frequently form large masses of fungal elements. We describe the case of a 12-year-old girl with hematologic remission of leukemia. She had a left ventricular pedunculated mass that wa... |
2,320,573 | Solitary intraventricular tuberculoma in adults. | Intracranial tuberculoma is typically located in the parenchyma. Lesions limited to the ventricular system are uncommon. It is difficult to make a differential diagnosis from other lesions if no systemic tuberculosis is present. This study investigates a case of solitary intraventricular tuberculoma in a 19-year-old fe... |
2,320,574 | Multilocated mature teratoma: a case report and review of the literature. | Mature teratomas are rare inclusion tumors, which have benign behaviors. Different locations of the tumor were reported in the literature. However, multiple tumor locations are extremely rare. An eight year old patient presented with an intraventricularly mature teratoma. During the six year follow up-period, two separ... |
2,320,575 | Neural stem cells transplanted into intact brains as neurospheres form solid grafts composed of neurons, astrocytes and oligodendrocyte precursors. | Neural stem cells (NSCs) are tissue-specific stem cells with self-renewal potential that can give rise to neurons and glia in vivo and in vitro. The aim of this study was to transplant NSCs as whole neurospheres into intact brain and assess the fate and phenotype of their progeny generated in vivo. We isolated NSCs fro... |
2,320,576 | Assessment of estrogenic endocrine-disrupting chemical actions in the brain using in vivo somatic gene transfer. | Estrogenic endocrine-disrupting chemicals abnormally stimulate vitellogenin gene expression and production in the liver of many male aquatic vertebrates. However, very few studies demonstrate the effects of estrogenic pollutants on brain function. We have used polyethylenimine-mediated in vivo somatic gene transfer to ... |
2,320,577 | Orexin inputs to caudal raphé neurons involved in thermal, cardiovascular, and gastrointestinal regulation. | Orexin-expressing neurons in the lateral hypothalamus with their wide projections throughout the brain are important for the regulation of sleep and wakefulness, ingestive behavior, and the coordination of these behaviors in the environmental context. To further identify downstream effector targets of the orexin system... |
2,320,578 | Tension pneumoventricle after placement of a ventriculoperitoneal shunt: a novel treatment strategy. Case report. | A case of pneumoventricle following insertion of a ventriculoperitoneal shunt for hydrocephalus is described. The pneumoventricle was associated with significant morbidity, which improved with treatment. The authors propose a rational treatment for this condition, which, as far as they know, has not previously been des... |
2,320,579 | Diminished myofibril organization in mutant axolotl hearts transfected with site-directed mutants of sarcomeric tropomyosins. | We used a model lacking endogenous sarcomeric tropomyosin, the cardiac mutant of the Mexican axolotl, to examine the effect of mutant tropomyosins on sarcomeric myofibril formation. Previous studies have introduced wild-type mouse alpha-tropomyosin into mutant hearts in organ culture with subsequent for-mation of organ... |
2,320,580 | mCD24 regulates proliferation of neuronal committed precursors in the subventricular zone. | We previously showed that deletion of the cell surface molecule mCD24 resulted in an increased proliferation in adult subventricular zone (SVZ). Here, we report an increased PSA-NCAM+/TuJ1- population in the mCD24-/- in vivo SVZ as well as in vitro neurospheres. Isolated in vitro, these cells were able to generate neur... |
2,320,581 | Pachygyria in a girl with microcephalic osteodysplastic primordial short stature type II. | We report a mild form of lissencephaly or a pachygyric brain in a girl with microcephalic osteodysplastic primordial 'dwarfism' (MOPD) type II. She was born with severe intrauterine growth failure. A diagnosis of MOPD type II was warranted by persistent postnatal growth failure, microcephaly with a Seckel-like facial a... |
2,320,582 | Effects of PFOS and PFOA on L-type Ca2+ currents in guinea-pig ventricular myocytes. | Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are amphiphiles found ubiquitously in the environment, including wildlife and humans, and are known to have toxic effects on physiological functions of various tissues. We investigated the effects of PFOS and PFOA on action potentials and L-type Ca(2+) curr... |
2,320,583 | The MLC1v gene provides a transgenic marker of myocardium formation within developing chambers of the Xenopus heart. | Many details of cardiac chamber morphogenesis could be revealed if muscle fiber development could be visualized directly within the hearts of living vertebrate embryos. To achieve this end, we have used the active promoter of the MLC1v gene to drive expression of green fluorescent protein (GFP) in the developing tadpol... |
2,320,584 | [Surgical technique in operations for brainstem gliomas]. | The article presents an MRI-based classification of brainstem gliomas into focal, cervicomedullary, dorsal exophytic and diffuse ones. This classification provides the basis for specifying indications for surgical treatment and outcome. The article also presents the most frequent approaches to the midbrain, pons and me... |
2,320,585 | Combined chemotherapy and radiotherapy for intracranial germinomas in adult patients: a single-institution study. | We report on our experience in the treatment of intracranial germinomas (18 pure germinomas and two germinomas with syncytiotrophoblastic giant cells) according to a strategy of radiotherapy doses and fields reduction after a neoadjuvant chemotherapy (Cisplatin-vinblastine and bleomycin combination). Radiation therapy ... |
2,320,586 | Up-regulation of neuropoiesis generating glial progenitors that infiltrate rat intracranial glioma. | To investigate adult neural stem cell (NSC) biology in relation to glioma, the C6 glioma cell line was tagged with green fluorescent protein (GFP) and inoculated into the brain of adult rats. The in vivo biological response of the brain to glioma was studied using immunohistochemical analysis of the subventricular zone... |
2,320,587 | Chronic administration of docosahexaenoic acid ameliorates the impairment of spatial cognition learning ability in amyloid beta-infused rats. | We investigated whether administration of docosahexaenoic acid (DHA), a major (n-3) fatty acid of the brain, ameliorates the impairment of learning ability in an animal model of Alzheimer's disease (AD), rats infused with amyloid-beta (Abeta) peptide (1-40) into the cerebral ventricle. Inbred 3rd generation male rats (... |
2,320,588 | Electrotonic influences on action potential duration dispersion in small hearts: a simulation study. | Intrinsic spatial variations in repolarization currents in the heart can produce spatial gradients in action potential duration (APD) that serve as possible sites for conduction block and the initiation of reentrant activity. In well-coupled myocardium, however, electrotonic influences at the stimulus site and wavefron... |
2,320,589 | Long-term survival in a child with a brain stem dermoid cyst. | Brain stem dermoid cysts are very rare lesions, and in most, the outcome has been very poor. Because of the dangers of dissecting the cyst wall away from the brain stem parenchyma, some authors have advocated not to attempt a radical resection.</AbstractText>We describe a child in whom the brain stem dermoid cyst recur... |
2,320,590 | Ventriculoperitoneal shunt of continuous flow vs valvular shunt for treatment of hydrocephalus in adults. | Shunting for hydrocephalus is the neurosurgical procedure most frequently associated with long-term complications. We developed an alternative to valvular shunts based on a simple shunt procedure whose functioning depends on a peritoneal catheter with a highly precise cross-sectional internal diameter of 0.51 mm. Preli... |
2,320,591 | Fractional Gaussian noise, functional MRI and Alzheimer's disease. | Fractional Gaussian noise (fGn) provides a parsimonious model for stationary increments of a self-similar process parameterised by the Hurst exponent, H, and variance, sigma2. Fractional Gaussian noise with H < 0.5 demonstrates negatively autocorrelated or antipersistent behaviour; fGn with H > 0.5 demonstrates 1... |
2,320,592 | Bcl-2 in endothelial cells is increased by vitamin E and alpha-lipoic acid supplementation but not exercise training. | Atherosclerotic plaque contains apoptotic endothelial cells with oxidative stress implicated in this process. Vitamin E and alpha-lipoic acid are a potent antioxidant combination with the potential to prevent endothelial apoptosis. Regular exercise is known to increase myocardial protection, however, little research ha... |
2,320,593 | Neuromedin-U is regulated by the circadian clock in the SCN of the mouse. | Neuromedin-U (NMU) has been reported to drive several physiological or behavioural responses following i.c.v. injection of the peptide into the third ventricle of rodent brains. Many of these responses are mediated through a change in corticotrophin-releasing factor (CRF) output from the paraventricular nucleus (PVN). ... |
2,320,594 | Supplemental inhaled gases alter tidal volume delivery and measurement. | Supplemental inspired nitrogen (N(2)) or carbon dioxide (CO(2)) is commonly used to balance pulmonary blood flow in patients with single-ventricle physiology. The objective of this study was to assess if supplemental inspired gas alters delivery or measurement of tidal volume (V(T)) by a ventilator.</AbstractText>Prosp... |
2,320,595 | An update on the biochemical diagnosis of congenital ACTH insufficiency. | Congenital ACTH insufficiency due to disorders of the hypothalamo-pituitary axis is life threatening. However, the optimal method for establishing the diagnosis remains controversial. The standard Synacthen test (SST) is safe and easy to perform in infancy, but its performance has not been well evaluated in infants and... |
2,320,596 | [A rare case of aqueductal stenosis due to venous angioma]. | Aqueductal stenosis is induced by widely various causes. These causes include congenital stenosis, tumor or inflammation. Among them vascular malformation is a very rare cause. In this paper we present a rare case of aqueductal stenosis caused by venous angioma. The patient was a 28-year-old female, who suffered from h... |
2,320,597 | Evaluation of factors predicting accurate resection of high-grade gliomas by using frameless image-guided stereotactic guidance. | Frameless image-guided stereotaxy is often used in the resection of high-grade gliomas. The authors of several studies, however, have suggested that brain shift may occur intraoperatively and result in inaccurate resection. To determine the usefulness of frameless stereotactic image-guided surgery of high-grade gliomas... |
2,320,598 | Molecular determination of the origin of acephalic cysticercus. | Acephalic cysticercus (Ac), a rarely developed multilobulated and nonencysted form of larval Taenia, causes hydrocephalus or adhesive arachnoiditis in the ventricles and subarachnoidal space that often lead to fatal outcome in affected patients. Ac has been proposed to originate from T. solium on the basis of morpholog... |
2,320,599 | Increased expression of vascular endothelial growth factor and capillary density in hearts of spontaneously hypertensive rats. | The role of VEGF in vascular remodeling of target organs exposed to chronic hypertension is poorly understood. The authors compared capillary density (CD), capillary-to-fiber ratio (C/F), and VEGF mRNA expression in the hearts (left ventricle [LV]), and skeletal muscles (soleus and anterior tibialis [AT]) of 18-week-ol... |
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