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2,320,600 | [Bruns' syndrome: description of a case of neurocysticercosis with pathological study]. | Bruns' syndrome is characterized by sudden and strong headache, accompanied by vomiting, acuphenos and vertigo, triggered by abrupt movement of the head and can produce deep coma and death. This can be due to neurocysticercosis by cyst in the fourth ventricle, which contains the larval stage of Taenia solium. In the la... |
2,320,601 | Age-related changes in lateral ventricle morphology in craniosynostotic rabbits using magnetic resonance imaging. | Craniosynostosis occurs in 300-500 per 1,000,000 live births and results in secondary craniofacial, ocular, and intracranial anomalies. Neurologic problems associated with craniosynostosis include changes in intracranial morphology such as dilation of the cerebral ventricles, however, clinical studies are confounded by... |
2,320,602 | White matter hyperintensities and chronicity of depression. | White matter hyperintensities (WMHs) on T(2)-weighted magnetic resonance imaging (MRI) of the brain are associated with advanced age and late-life depression. Most investigations predominantly found these lesions in frontal lobe and basal ganglia supporting the hypothesis of a fronto-striatal dysfunction in depression.... |
2,320,603 | [Left ventricle TEI index--assessment of clinical role in patients with aortic valve stenosis].<Pagination><StartPage>560</StartPage><EndPage>562</EndPage><MedlinePgn>560-2</MedlinePgn></Pagination><Abstract><AbstractText Label="AIM" NlmCategory="OBJECTIVE">The study aimed to assess the clinical efficacy of the TEI ind... | Finoptin and obzidane influence on morphologic signs of intact ventricular cardiac hystiocytes has been examined during the experiments on animals by means of the complex of histological and histochemical methods, electron microscopy as well as morphometry. It has been established that long-term using of finoptin and o... |
2,320,604 | Cardiac syntrophin isoforms: species-dependent expression, association with dystrophin complex and subcellular localization. | Syntrophin is known to be a component of the dystrophin-glycoprotein complex (DGC), a membrane/cytoskeleton-anchoring structure that is essential for the maintenance of viability of sarcolemma. We purified DGC from hearts of human and several animal species, and compared their protein composition. While almost all comp... |
2,320,605 | Frameless stereotactic ventricular shunt placement for idiopathic intracranial hypertension. | Cerebrospinal fluid (CSF) shunting effectively reverses symptoms of idiopathic intracranial hypertension (IIH). Lumboperitoneal (LP) shunts have traditionally been used in patients with IIH due to a frequently undersized ventricular system. However, the advent of image-guided stereotaxis has enabled effective ventricul... |
2,320,606 | Real-time cine MRI of ventricular septal motion: a novel approach to assess ventricular coupling. | The purpose of this study was to assess the feasibility of magnetic resonance imaging (MRI) to evaluate in real-time, the effects of respiration in ventricular septal motion and configuration in normal volunteers and cardiac patients. Real-time cine MRI studies, using the steady-state free precession (SSFP) technique, ... |
2,320,607 | An automated algorithm for combining multivoxel MRS data acquired with phased-array coils. | To develop a fully automated algorithm for combining multivoxel magnetic resonance spectroscopy (MRS) data acquired with a phased-array coil.</AbstractText>The frequency-domain fitting method of LCModel (Provencher SW, Magn Reson Med 1993;30:672-679) was utilized to analyze the individual data sets. The phase correctio... |
2,320,608 | Hypothalamic hamartoma: a paradigm/model for studying the onset of puberty. | This article discusses the potential mechanisms by which hypothalamic hamartomas (HHs) are formed and cause precocious puberty. The hypothesis is presented suggesting that HHs accelerate sexual development by producing bioactive substances that mimic - in an accelerated time-course - the cascade of events underlying th... |
2,320,609 | Apico-basal inhomogeneity in distribution of ion channels in canine and human ventricular myocardium. | The aim of the present study was to compare the apico-basal distribution of ion currents and the underlying ion channel proteins in canine and human ventricular myocardium.</AbstractText>Ion currents and action potentials were recorded in canine cardiomyocytes, isolated from both apical and basal regions of the heart, ... |
2,320,610 | Assays for measuring extracellular GABA levels and cell migration rate in acute slices. | The postnatal subventricular zone (SVZ) contains the largest pool of dividing and migrating neural precursors in the adult rodent brain. Neuronal precursors migrate throughout the SVZ and along the rostral migratory stream (RMS) towards the olfactory bulb where they differentiate into interneurons. To facilitate the in... |
2,320,611 | Central neuropeptide Y receptors are involved in 3rd ventricular ghrelin induced alteration of colonic transit time in conscious fed rats. | Feeding related peptides have been shown to be additionally involved in the central autonomic control of gastrointestinal functions. Recent studies have shown that ghrelin, a stomach-derived orexigenic peptide, is involved in the autonomic regulation of GI function besides feeding behavior. Pharmacological evidence ind... |
2,320,612 | Adult neural stem cell therapy: expansion in vitro, tracking in vivo and clinical transplantation. | Neural stem cells (NSCs) are present not only in the developing nervous systems, but also in the adult human central nervous system (CNS). It is long thought that the subventricular zone of the lateral ventricles and the dentate gyrus of the hippocampus are the main sources of human adult NSCs, which are considered to ... |
2,320,613 | [PAX6 mutation caused brain abnormalities in humans]. | To investigate the association between PAX6 mutation and brain abnormalities.</AbstractText>The brain structures of 18 affected patients and 6 normal controls in a large pedigree with a PAX6 mutation (c1080C-->T)were scanned with MRI assessing.</AbstractText>Most of the affected patients showed brain abnormalities s... |
2,320,614 | Cardiac MR image segmentation and left ventricle surface reconstruction based on level set method. | A two-stage segmentation algorithm is presented to solve the problems of inhomogeneity, weak edges and artifacts exhibited in the magnetic resonance imaging (MRI) images. First, the K-mean clustering algorithm is applied to classify the objects. Then, a speed function based on the clustering results is defined in order... |
2,320,615 | The vasotocinergic system in the hypothalamus and limbic region of the budgerigar (Melopsittacus undulatus). | We report a morphological and biochemical analysis on the presence, distribution and quantification of vasotocin in the hypothalamus and limbic region of the budgerigar Melopsittacus undulatus, using immunohistochemistry on serial sections and competitive enzyme linked immunoadsorbent assay measurements on tissue extra... |
2,320,616 | Aging affects choroidal proteins involved in CSF production in Sprague-Dawley rats. | Aging is currently associated with progressive declines of cerebral functions. From these, a decreased resistance to dehydration suggested alteration in choroidal control of brain homeostasis and reduced cerebrospinal fluid (CSF) production in old subjects. In the present study, choroid plexuses of 20-month old Sprague... |
2,320,617 | A method to accurately inject tumor cells into the caudate/putamen nuclei of the mouse brain. | To improve currently used techniques to implant tumor cells into the parenchyma of the mouse brain.</AbstractText>The stereotactic injection of 0.5 to 5 microl of indigo carmine over 5 to 40 minutes into the caudate/putamen nuclei of the mouse was done followed by sacrifice and examination of the brain injection site. ... |
2,320,618 | Toll-like receptor 4 on nonhematopoietic cells sustains CNS inflammation during endotoxemia, independent of systemic cytokines. | Inflammatory agonists such as lipopolysaccharide (LPS) induce robust systemic as well as CNS responses after peripheral administration. Responses in the innate immune system require triggering of toll-like receptor 4 (TLR4), but the origin of CNS sequelas has been controversial. We demonstrate expression of TLR4 transc... |
2,320,619 | Retinal-specific ATP-binding cassette transporter (ABCR/ABCA4) is expressed at the choroid plexus in rat brain. | ATP-binding cassette (ABC) transporter A4 is a member of the ABC transporter subfamily A which has been reported to be exclusively expressed in the retina. In contrast, a previous report has suggested a possible relationship between ABCA4 and CNS function. The purpose of the present study was to investigate the localiz... |
2,320,620 | [Case of a young woman successfully operated on for acute pulmonary embolism and right ventricular thrombus after urogenital infection].<Pagination><StartPage>33</StartPage><EndPage>36</EndPage><MedlinePgn>33-6</MedlinePgn></Pagination><Abstract><AbstractText>The authors report a case of a 22-year-old women operated on... | The authors report a case of a 22-year-old women operated on for pulmonary embolism with success. The venous embolism developed in two phases one week apart. The first clinical sign was a dyspnea of abrupt onset limiting physical activity even after a mild exertion. However, relevant diagnostic tests were performed aft... |
2,320,621 | The choroid plexus in the rise, fall and repair of the brain. | The choroid plexuses (CPs) are involved in the most-basic aspects of neural function including maintaining the extracellular milieu of the brain by actively modulating chemical exchange between the CSF and brain parenchyma, surveying the chemical and immunological status of the brain, detoxifying the brain, secreting a... |
2,320,622 | Air encephalography for hydrocephalus in the era of neuroendoscopy. | There is often uncertainty regarding the site of the cerebrospinal fluid (CSF) block in individual patients with hydrocephalus, leading to a significant failure rate for endoscopic third ventriculostomy (ETV) when performed for unconventional pathologies such as postmeningitic and posthaemorrhagic hydrocephalus. We des... |
2,320,623 | Tissue-specific transcriptome responses in rats with early streptozotocin-induced diabetes. | The understanding of common and tissue-specific molecular alterations in diabetes, particularly at early stages, is limited and fragmental. In the present study, we systematically compared transcriptome responses in four important diabetic target tissues in rats with 2 wk of streptozotocin (STZ)-induced diabetes. At th... |
2,320,624 | Fumonisin B1-induced neurodegeneration in mice after intracerebroventricular infusion is concurrent with disruption of sphingolipid metabolism and activation of proinflammatory signaling. | Fumonisin B1 (FB1), a mycotoxin produced by Fusarium verticillioides, causes equine leukoencephalomalacia, a condition not reproduced in any other species. We hypothesized that direct exposure of murine brain to FB1 will result in neurotoxicity, characterized by biochemical and pathological alterations. The present stu... |
2,320,625 | Inhibition of trigemino-hypoglossal reflex in rats by oxytocin is mediated by mu and kappa opioid receptors. | Recent studies showed that oxytocin plays an important role in the modulation of pain at different levels of the central nervous system. The present study was undertaken to investigate the effect of oxytocin on trigemino-hypoglossal reflex in rats. With the experimental settings used in this study, we have demonstrated... |
2,320,626 | Reductions in spontaneous locomotor activity in aged male, but not female, rats in a model of early Parkinson's disease. | The excessive loss of dopamine (DA) neurons that occurs with Parkinson's disease is usually confined to older individuals. While 6-hydroxydopamine (6-OHDA) is often used in animal models of DA neuron degeneration, there have been relatively few studies that have examined the effects of 6-OHDA in older animals. In the p... |
2,320,627 | Severe intrauterine growth restriction and trisomy 15 confined placental mosaicism: a case report and review of literature. | To correlate confined placental mosaicism (CPM) for trisomy 15 with severe intrauterine growth restriction (IUGR) and early death after birth (age of 6 months).</AbstractText>Chromosome analysis was performed on amniotic fluid at 21st week of gestation, on peripheral blood at birth and on fibroblasts at death using con... |
2,320,628 | Do the asymmetry and the size of the structures of the temporal lobe persist in early stages of schizophrenia? | A total of 14 patients of various ages diagnosed with schizophrenia and, as an age-matched control group, 12 healthy subjects were examined using the MRI method of neuro-imaging. The volume of the following structures was evaluated in the right and left hemispheres: the superior temporal gyrus, the basolateral temporal... |
2,320,629 | Does asymptomatic septal agenesis exist? A review of 34 cases. | Primary septal agenesis (PSA) is a rare brain malformation that can be isolated or part of developmental brain abnormalities (holoprosencephaly, septo-optic dysplasia or cortical malformation). Such associated malformation can be subtle, leading to difficulties in the prenatal management of PSA. Moreover, the neurologi... |
2,320,630 | Fibroblast growth factor 2 is required for maintaining the neural stem cell pool in the mouse brain subventricular zone. | Cells within the subventricular zone (SVZ) express basic Fgf (Fgf2) and Fgf receptor proteins. We show that the absence of Fgf2 gene products reduces by 50% the dividing progenitor population of the anterior SVZ (SVZa) without changing their cell cycle time. Every 2-3 cell cycles of the SVZa progenitor cell population,... |
2,320,631 | Teneurin proteins possess a carboxy terminal sequence with neuromodulatory activity. | We have previously shown that a bioactive neuropeptide-like sequence is present at the carboxy-terminus of the teneurin transmembrane proteins. We have subsequently called this peptide 'teneurin C-terminal associated peptide' (TCAP). The sequence encodes a peptide 40 or 41 amino acids long flanked by a cleavage motif o... |
2,320,632 | Cerebral density on CT immediately after a successful resuscitation of cardiopulmonary arrest correlates with outcome. | To evaluate whether cerebral CT findings taken immediately after successful resuscitation from cardiopulmonary arrest (CPA) correlate with the outcome or not.</AbstractText>We analyzed retrospectively brain sections with the Housfield unit (CT number). Between May 2001 and March 2004, 16 consecutive patients, who recov... |
2,320,633 | Regional brain atrophy evolves differently in patients with multiple sclerosis according to clinical phenotype. | Progressive brain atrophy is a well-known feature of multiple sclerosis (MS). We characterized the spatial evolution of atrophy in different MS phenotypes.</AbstractText>Dual-echo and T1-weighted MR images were obtained in 70 patients with MS and 10 healthy control subjects at entry and after 15 months. Within-group ch... |
2,320,634 | Central H1 and H2 receptor participation in the control of water and salt intake in rats. | The aim of the present study was to evaluate the participation of brain H1 and H2 histaminergic receptors on water and salt intake induced by water deprivation (24 h), furosemide-induced sodium depletion and central angiotensinergic pharmacological stimulation in rats. Third ventricle injections of the H1 and H2 recept... |
2,320,635 | Region and volume dependencies in spectral line width assessed by 1H 2D MR chemical shift imaging in the monkey brain at 7 T. | High magnetic fields increase the sensitivity and spectral dispersion in magnetic resonance spectroscopy (MRS). In contrast, spectral peaks are broadened in vivo at higher field strength due to stronger susceptibility-induced effects. Strategies to minimize the spectral line width are therefore of critical importance. ... |
2,320,636 | External ventricular drains: is there a time limit in children? | <AbstractText Label="BACKGROUND/PURPOSE" NlmCategory="OBJECTIVE">The time limit for the use of external ventricular drains (EVDs) has always been controversial. The purpose of this study is to find out if there is a time limit with regard to infection of EVDs and their duration of use in children.</AbstractText>The rec... |
2,320,637 | Transduction of the choroid plexus and ependyma in neonatal mouse brain by vesicular stomatitis virus glycoprotein-pseudotyped lentivirus and adeno-associated virus type 5 vectors. | Evaluation of gene transfer into the developing mouse brain has shown that when adeno-associated virus serotype 1 (AAV1) or AAV2 vectors are injected into the cerebral lateral ventricles at birth, widespread parenchymal transduction occurs. Lentiviral vectors have not been tested by this route. In this study, we found ... |
2,320,638 | Neurolisteriosis causing hydrocephalus, trapped fourth ventricle, hindbrain herniation and syringomyelia. | Central nervous system infection by Listeria monocytogenes is relatively uncommon, but is known to be highly morbid and fatal. We describe a case of listeria meningoencephalitis, wherein the acute episode was followed by a hitherto unreported conglomeration of severe and progressive neurological sequelae, in the form o... |
2,320,639 | Massive symptomatic subependymoma of the lateral ventricles: case report and review of the literature. | Subependymomas are benign intraventricular tumors with an indolent growth pattern, which are usually asymptomatic, and most commonly occur in the fourth and lateral ventricles. When symptomatic, subependymomas often obstruct critical portions of the cerebrospinal fluid (CSF) pathway, causing hydrocephalus, and range fr... |
2,320,640 | Identification and characterization of rat Ror1 and Ror2 genes in silico. | Frizzled-1 (FZD1), FZD2, FZD3, FZD4, FZD5, FZD6, FZD7, FZD8, FZD9 and FZD10 are seven-transmembrane-type WNT receptors with extracellular Frizzled (Fz) domain. ROR1, ROR2 and MUSK are receptor-type tyrosine kinases with extracellular Fz domain, while MFRP is type II transmembrane protein with extracellular Fz domain. R... |
2,320,641 | A case of isolated langerhans cell histiocytosis of the hypothalamus with remission and regrowth after surgery. | We describe a new case of isolated Langerhans cell histiocytosis (LCH) of the hypothalamus. A 53-year-old female patient presented with polydipsia, headache, anorexia, and fatigue. Neurological imaging revealed a mass projecting from the hypothalamus into the third ventricle. Gross total removal of the tumor was perfor... |
2,320,642 | Late-onset multiple sclerosis mimicking brain tumor: a case report. | Multiple sclerosis (MS) is a demyelinating disease that predominantly affects those aged in their twenties to their forties. We recently observed a case of rapidly progressive late-onset MS in an elderly patient with a large, single lesion on magnetic resonance imaging (MRI), which was difficult to distinguish from a b... |
2,320,643 | The clinical impact of magnetic resonance imaging in fetuses with central nervous system anomalies on ultrasound scan. | Magnetic resonance imaging (MRI) was performed on fetuses with sonographically diagnosed central nervous system (CNS) anomalies to determine frequency and type of cases in which fetal MRI adds clinically relevant information.</AbstractText>Forty-three cases presenting with CNS anomalies by ultrasonography were investig... |
2,320,644 | Reduced sarcoplasmic reticulum Ca2+ uptake and increased Na+-Ca2+ exchanger expression in left ventricle myocardium of dogs with progression of heart failure.<Pagination><StartPage>23</StartPage><EndPage>32</EndPage><MedlinePgn>23-32</MedlinePgn></Pagination><Abstract><AbstractText>Alteration of intracellular Ca(2+) ho... | Alteration of intracellular Ca(2+) homeostasis in failing cardiomyocytes is associated with changes in regulatory proteins located in the sarcoplasmic reticulum (SR) and sarcolemma, which participate in Ca(2+) fluxes across the membrane during the cardiac cycle. These regulatory proteins include Ca(2+)-ATPase (SERCA 2A... |
2,320,645 | In vivo labeling of neuroblasts in the subventricular zone of rats. | The studies of neural stem cell fate, as well as the possibility to genetically manipulate them, represent important tools for modern neuroscience research. Furthermore, the potential use of these cells in treatment of neurological disorders makes these methods valuable for the development of new treatment paradigms. H... |
2,320,646 | Fibroblast growth factor 2 induces loss of adult oligodendrocytes and myelin in vivo. | Oligodendrocytes are the myelin-forming cells of the CNS and are lost in demyelinating diseases such as multiple sclerosis (MS). A role for fibroblast growth factor 2 (FGF2) has been proposed in the pathogenesis of demyelination and the failure of remyelination in experimental models of MS. However, the in vivo effects... |
2,320,647 | [Histopathology study of supraglottic carcinoma with different vocal cord movement]. | To explore the histopathology characteristics of supraglottic carcinoma with different vocal cord movement, and to find the theory basis for partial laryngectomy.</AbstractText>Eighty-four cases of supraglottic laryngeal carcinoma specimen were imbedded in collodion, and then make whole-organ serial section for HE stai... |
2,320,648 | Outcome of endoscopic third ventriculostomy. Results from an unselected series with noncommunicating hydrocephalus. | Endoscopic third ventriculostomy (ETV) has gained acceptance as the treatment of choice for noncommunicating hydrocephalus despite a relatively high failure rate and a higher surgical risk than the placement of a shunt. The benefits of shunt independence overcome both drawbacks. This argument also serves to consider ca... |
2,320,649 | Placental perfusion MR imaging with contrast agents in a mouse model. | To quantitatively analyze placental perfusion by using magnetic resonance (MR) imaging with contrast agents in a mouse model.</AbstractText>Study was conducted according to French law and in full compliance with National Institutes of Health recommendations for animal care. Thirty-six pregnant Balb/c mice at 16 days of... |
2,320,650 | [Noncompacted cardiomyopathy of the left ventricule]. | In response to a recent review on the role of MRI in the evaluation of cardiomyopathies, we wished, through a clinical example, to focus the attention on noncompacted cardiomyopathy of the left ventricule, an under-diagnosed entity at the border of pediatric and adult imaging, because of its congenital nature but of la... |
2,320,651 | Characterization of brain plasticity in schizophrenia using template deformation. | Abnormal neurodevelopment may play a role in the pathophysiology of schizophrenia. We used deformation-based morphometry to examine voxel-wise age-related changes in patients with schizophrenia compared with healthy brains.</AbstractText>We used a set of skull-stripped brains from an image database of cranial magnetic ... |
2,320,652 | How should primary aqueductal stenosis in adults be treated? A review. | In 10% of adult patients with hydrocephalus, the cause is because of aqueductal stenosis (AS), causing enlargement of the lateral and third ventricles. There are currently two alternate forms of surgical treatment for AS; shunt surgery and ventriculostomy. Shunt surgery is associated with high complication rates and ma... |
2,320,653 | Dose-dependent neurochemical and functional protection afforded by encapsulated CNTF-producing cells. | Intracerebral delivery of hCNTF has shown considerable neuroprotective potential in animal models of Huntington's disease (HD). The present study describes the relationship between a range of hCNTF doses and the resulting behavioral and neurochemical (striatal ChAT and GAD activity) protection in a rodent model of HD. ... |
2,320,654 | Rosette-forming glioneuronal tumour of the fourth ventricle: report of a case with clinical and surgical implications. | A 32-year-old woman presented with a 2-month history of episodic headache, cervical pain and neck rigidity. Neurological examination showed a moderate dysmetria. Magnetic resonance imaging (MRI) revealed a mass occupying the fourth ventricle. The patient underwent median sub-occipital craniotomy with total excision of ... |
2,320,655 | Intraventricular tanycytic ependymoma: case report and review of the literature. | Tanycytic ependymomas are a rare ependymoma subtype showing a marked predilection for the spine, with only a few reports of supratentorial tumors. We present a case of a tanycytic ependymoma arising from the lateral and third ventricle.</AbstractText>The patient was a 55-year-old woman who complained of intermittent, p... |
2,320,656 | Effect of erythropoietin on bcl-2 gene expression in rat cardiac myocytes after traumatic brain injury. | The purpose of this study was to investigate whether erythropoietin (EPO) has an effect on the expression of bcl-2 in rat cardiac myocytes following experimental isolated traumatic brain injury (TBI). Forty-eight Wistar-Albino female rats were randomly allocated into eight groups. Groups AC and BC were controls; groups... |
2,320,657 | Widespread and highly persistent gene transfer to the CNS by retrovirus vector in utero: implication for gene therapy to Krabbe disease. | Brain-directed prenatal gene therapy may benefit some lysosomal storage diseases that affect the central nervous system (CNS) before birth. Our previous study showed that intrauterine introduction of recombinant adenoviruses into cerebral ventricles results in efficient gene transfer to the CNS in the mouse. However, t... |
2,320,658 | Calcification on the ventricle wall associated with a shunt tube--case report. | A 53-year-old man with renal failure presented with symptoms of shunt malfunction 11 years after placement of a ventriculoperitoneal shunt. Computed tomography showed high-density lesions on the lateral ventricle wall around the shunt tube. The shunt tube was replaced under monitoring with a neuroendoscope. The resecte... |
2,320,659 | Influence of the shunt type in the difference in reduction of volume between the two lateral ventricles in shunted hydrocephalic children. | After shunt insertion there is commonly a disproportionate reduction in size of the lateral ventricle containing the catheter (shunted lateral ventricle), which is almost certainly related to shunt function. To explore the difference between two shunt types, the Differential Pressure Medium Pressure cylindrical (M.P.) ... |
2,320,660 | A chick model for the mechanisms of mustard gas neurobehavioral teratogenicity. | The chemical warfare blistering agent, sulfur mustard (SM), is a powerful mutagen and carcinogen. Due to its similarity to the related chemotherapy agents nitrogen mustard (mechlorethamine), it is expected to act as a developmental neurotoxicant. The present study was designed to establish a chick model for the mechani... |
2,320,661 | Grafts of adult subependymal zone neuronal progenitor cells rescue hemiparkinsonian behavioral decline. | Neuronal progenitor cells (NPCs) residing in the adult subependymal zone (SEZ) are a potential source of expandable cells for autologous transplantation to treat Parkinson's Disease and other types of brain injury. We have previously demonstrated the capacity of transplanted adult SEZ NPCs for heterotypic differentiati... |
2,320,662 | Early outcome after Glenn shunt and Fontan palliation and the impact of operation during viral respiratory season: analysis of a 19-year multi-institutional experience. | This study was done to investigate the impact of season of operation, age at operation, and surgical era on short-term outcome after single ventricle palliation. One small study suggests that operation during viral respiratory season is associated with prolonged pleural effusion and hospitalization. Single-institution ... |
2,320,663 | Proliferation, migration, and differentiation of endogenous ependymal region stem/progenitor cells following minimal spinal cord injury in the adult rat. | Ependymal cells of the adult mammalian spinal cord exhibit stem/progenitor cell properties following injury. In the present study, we utilized intraventricular injection of 1,1'-dioctadecyl-6,6'-di(4-sulfophenyl)-3,3,3',3'-tetramethylindocarbocyanine (DiI) to label the ependyma lining the central canal to allow trackin... |
2,320,664 | Glutamate enhances survival and proliferation of neural progenitors derived from the subventricular zone. | Extracellular glutamate levels increase as a consequence of perinatal hypoxia/ischemia, causing the death of neurons and oligodendrocytes. Precursors in the subventricular zone (SVZ) also die following perinatal hypoxia/ischemia; therefore we hypothesized that glutamate would stimulate the death of neural precursors. H... |
2,320,665 | A brainstem cavernoma demonstrating a dramatic, spontaneous decrease in size during follow-up: case report and review of the literature. | Many reports have demonstrated a worse prognosis for patients whose cavernomas were subtotally removed than for those whose cavernomas were not surgically treated. Therefore, it is better not to touch the cavernoma if a surgeon is not prepared to totally remove it. This report describes a large brainstem cavernoma show... |
2,320,666 | Expression of mineralocorticoid receptors mRNA in the brain, heart and kidney of Sprague Dawley rats with renovascular hypertension. | A large body of evidence indicates that mineralocorticoids play significant role in regulation of cardiovascular functions and in pathogenesis of several forms of hypertension by means of multiple effects exerted in the brain, heart and kidney. However, little is known about regulation of expression of mineralocorticoi... |
2,320,667 | Low molecular weight glycosaminoglycan C3 attenuates AF64A-stimulated, low-affinity nerve growth factor receptor-immunoreactive axonal varicosities in the rat septum. | Glycosaminoglycans (GAGs) play a pivotal role in the pathogenesis of Alzheimer's disease (AD). Although, as we have shown earlier, a low molecular weight GAG, C3, protects against ethylcholine aziridinium (AF64A)-induced cholinergic damage, and against A(beta)-induced tau-2-immunoreactivity (IR), the mechanism of the n... |
2,320,668 | Comparison of pharmacological activities of Neuropeptide FF1 and Neuropeptide FF2 receptor agonists. | The pharmacological effects of Neuropeptide FF (NPFF) analogs exhibiting different selectivities towards Neuropeptide FF1 (NPFF1) and Neuropeptide FF2 (NPFF2) receptors were investigated after supraspinal administration in mice. Injected into the third ventricle, VPNLPQRF-NH2, which is selective for Neuropeptide FF1 re... |
2,320,669 | Effects of rosiglitazone and interactions with growth-regulating factors in ventricular cell hypertrophy. | Chronic administration of thiazolidinediones might predispose to cardiac hypertrophy. The aim was to investigate direct effects of rosiglitazone in rat ventricular cardiomyocytes maintained in vitro (24 h). Rosiglitazone (< or =10(-5) M) did not increase protein synthesis and produced small inconsistent increases in... |
2,320,670 | Mechanisms underlying anorexia after microinjection of bombesin into the lateral cerebroventricle. | Intracerebroventricular (i.c.v.) injections of bombesin (BN) and gastrin-releasing peptide (GRP) dose-dependently decreased food intake in male Wistar rats fasted for 17 h. Neuromedin B (NMB) did not show any effect on food intake. After BN administration, locomotor activity did not significantly change, compared with ... |
2,320,671 | Morphological differences among cavum septi pellucidi obtained in patients with schizophrenia and healthy individuals: forensic implications. A post-mortem study. | Cavum septi pellucidi (CSP), especially when longer than 6 mm, has been recognized as a neurodevelopmental anomaly associated with schizophrenia. The present post-mortem study was designed to determine the importance of linear parameters of CSP and to evaluate the possible differences of CSP in schizophrenic patients (... |
2,320,672 | Primary localized laryngeal amyloidosis: report of 3 cases with long-term follow-up and review of the literature. | Localized laryngeal amyloidosis is an uncommon condition with limited long-term follow-up studies. The precise etiology and pathogenesis are not entirely clear.</AbstractText>To further characterize the histopathologic features and possible pathogenesis of localized laryngeal amyloidosis.</AbstractText>Three cases of p... |
2,320,673 | De novo cerebellar medulloblastoma in a 26-year recurrence-free case of temporal glioblastoma multiforme. Case report. | The authors describe a patient who survived 26 years after resection of a right temporal glioblastoma multiforme (GBM) without signs of tumor recurrence. Preoperative emergency angiography demonstrated a hypovascular mass localized in the right temporal lobe with right-to-left shift of the vascular structures. At surge... |
2,320,674 | Larger brains in medication naive high-functioning subjects with pervasive developmental disorder. | Are brain volumes of individuals with Pervasive Developmental Disorder (PDD) still enlarged in adolescence and adulthood, and if so, is this enlargement confined to the gray and/or the white matter and is it global or more prominent in specific brain regions.</AbstractText>Brain MRI scans were made of 21 adolescents wi... |
2,320,675 | Three-dimensional myofiber architecture of the embryonic left ventricle during normal development and altered mechanical loads. | Mechanical load influences embryonic ventricular growth, morphogenesis, and function. To date, little is known regarding how the embryonic left ventricular (LV) myocardium acquires a three-dimensional (3D) fiber architecture distribution or how altered mechanical load influences local myofiber architecture. We tested t... |
2,320,676 | Development of paraventricular nucleus (PVN) associated with immunoreactivity to tyrosine hydroxylase (TH) in the second half of gestation. | The aim of this study was to shed more light on the developmental characteristics of human paraventricular nucleus (PVN) and hypothalamus in general, using modern immunohistochemical techniques to detect the activity of tyrosine hydroxylase (TH) in the synthesis of catecholamine (CA). Fetal brains were examined at 12, ... |
2,320,677 | Neuronavigation-guided endoscopic surgery for pineal tumors with hydrocephalus. | We have applied the neuronavigation system to endoscopic biopsy and third ventriculostomy in the management of patients with a pineal tumor with hydrocephalus. With the guidance of neuronavigation, the two optimal sites of burr hole and trajectories were planned preoperatively, and the advancing endoscopic device was m... |
2,320,678 | Endoscopic selective sampling of human ventricular CSF: a new perspective. | Neuroendoscopy has achieved extensive acceptance among neurosurgeons as a minimally invasive technique for the treatment of patients affected by blocked hydrocephalus. During endoscopic procedures minimal CSF amounts from selected anatomic sites of the ventricles can be withdrawn. Steerable endoscopes are used and thei... |
2,320,679 | Endoscopic third ventriculostomy for patients with hydrocephalus and fourth ventricular cysticercosis: a review of five cases. | The authors evaluate the feasibility of performing endoscopic third ventriculostomy (ETV) in a series of five patients with ventricular outlet obstruction and a prior history of fourth ventricular cysticercosis. All patients underwent fourth ventricular cyst excision and presented at various times afterwards with hydro... |
2,320,680 | Failure of endoscopic third ventriculostomy in the treatment of idiopathic normal pressure hydrocephalus. | Even though the main indication for neuroendoscopic management of normal pressure hydrocephalus (NPH) is the presence of an aqueductal block, recent reports suggest the possible efficacy of endoscopic third ventriculostomy (ETVS) in idiopathic NPH. We present 14 cases with apparently idiopathic NPH treated by ETVS, and... |
2,320,681 | Variations of endoscopic ventricular anatomy in children suffering from hydrocephalus associated with myelomeningocele. | Thirty-four patients less than 4 months old and suffering from hydrocephalus associated with myelomeningocele (MM) underwent endoscopic surgery to treat the hydrocephalus. The myelomeningocele was treated prior to our surgical intervention. We have found that different endoscopic anatomies of the ventricles exist betwe... |
2,320,682 | Changes of [3H]MK-801, [3H]muscimol and [3H]flunitrazepam binding in rat brain by the prolonged ventricular infusion of transformed ginsenosides. | Ameliorating effects of ginseng were observed on neuronal cell death associated with ischemia or glutamate toxicity. Ginseng saponins are transformed by intestinal microflora and the transformants would be absorbed from intestine. In the present study, we have investigated the effects of transformed ginsenoside Rg3, Rh... |
2,320,683 | Dose dependent accretion of docosahexaenoic acid (DHA) in cardiac membranes of rats fed egg yolk powder enriched in DHA. | We tested the hypothesis that enrichment of the diet with docosahexaenoic acid (DHA) enriched egg yolk powder could modify specifically the (n-3) fatty acids content of rat plasma, red blood cells and heart membranes. Dose-dependent effect of DHA was studied in rats supplemented during 4 weeks. Three groups of adult ma... |
2,320,684 | The MRL mouse heart healing response shows donor dominance in allogeneic fetal liver chimeric mice. | We previously demonstrated that after a severe cryoinjury to the right ventricle of the heart, adult MRL mice display structural and functional recovery with myocardial tissue replacement resembling that seen in amphibians. The control non-regenerating adult C57BL/6 (B6) mouse shows a predominant scar response. In the ... |
2,320,685 | Modulation of Alzheimer's pathology by cerebro-ventricular grafting of hybridoma cells expressing antibodies against Abeta in vivo. | Accumulation in brain of the beta-amyloid peptide (Abeta) is considered as crucial pathogenic event causing Alzheimer's disease (AD). Anti-Abeta immune therapy is a powerful means for Abeta clearance from the brain. We recently showed that intravenous injections of anti-Abeta antibodies led to reduction, elevation or n... |
2,320,686 | Segmentation of brain structures in presence of a space-occupying lesion. | Brain deformations induced by space-occupying lesions may result in unpredictable position and shape of functionally important brain structures. The aim of this study is to propose a method for segmentation of brain structures by deformation of a segmented brain atlas in presence of a space-occupying lesion. Our approa... |
2,320,687 | Shunt-related abdominal metastases in a child with choroid plexus carcinoma: case report. | Metastasis of primary brain neoplasms to the abdomen through a ventriculoperitoneal shunt (VPS) has been described for many types of tumors, including medulloblastoma, germ cell tumors, astrocytoma, oligodendroglioma, lymphoma, ependymoma, and melanoma. Choroid plexus tumors (CPTs) are located within the cerebrospinal ... |
2,320,688 | The role of stereotactic radiosurgery for low-grade astrocytomas. | This study was conducted to examine the role of radiosurgery in the management of patients with recurrent or unresectable low-grade astrocytomas.</AbstractText>During a 13-year interval, 49 patients underwent stereotactic radiosurgery as part of multimodal treatment of their recurrent or unresectable low-grade astrocyt... |
2,320,689 | A comparison of Monte Carlo and Fermi-Eyges-Hogstrom estimates of heart and lung dose from breast electron boost treatment. | Electrons are commonly used in the treatment of breast cancer primarily to deliver a tumor bed boost. We compared the use of the Monte Carlo (MC) method and the Fermi-Eyges-Hogstrom (FEH) algorithm to calculate the dose distribution of electron treatment to normal tissues.</AbstractText>Ten patients with left-sided bre... |
2,320,690 | Controlling neural stem cell division within the adult subventricular zone: an APPealing job. | For years, scientists investigating amyloid precursor protein (APP) have focused on its pathogenetic role in the brains of Alzheimer's disease patients. Now, a study by Caille et al. adds new sites of action and new physiological functions for APP. They show that there are binding sites for secreted N-terminal nonamylo... |
2,320,691 | Spinal intramedullary ependymal cyst: a case report and review of the literature. | We report a rare case of spinal intramedullary ependymal cyst in a 44-year-old female and reviewed 12 cases reported in the literature. The patient presented with slowly progressive lower limb paresis. She underwent biopsy of the cyst wall and placement of a cysto-subarachnoid shunt with complete recovery at the follow... |
2,320,692 | Bilateral abducent and facial nerve palsies following fourth ventricle shunting: two case reports. | Treatment of isolated fourth ventricle syndrome is difficult and there is no widely agreed method. Fourth ventriculo-peritoneal shunting is the most commonly utilized procedure for the management of this syndrome. Complications from shunting are common and are usually related to malfunction, infection, dislocation and ... |
2,320,693 | Kisspeptin activation of gonadotropin releasing hormone neurons and regulation of KiSS-1 mRNA in the male rat. | The KiSS-1 gene codes for a family of neuropeptides called kisspeptins which bind to the G-protein-coupled receptor GPR54. To assess the possible effects of kisspeptins on gonadotropin secretion, we injected kisspeptin-52 into the lateral cerebral ventricles of adult male rats and found that kisspeptin-52 increased the... |
2,320,694 | Paradoxical loss of excitation with high intensity pulses during electric field stimulation of single cardiac cells. | Transmembrane potential responses of single cardiac cells stimulated at rest were studied with uniform rectangular field pulses having durations of 0.5-10 ms. Cells were enzymatically isolated from guinea pig ventricles, stained with voltage sensitive dye di-8-ANEPPS, and stimulated along their long axes. Fluorescence ... |
2,320,695 | Tandem action of exercise training and food restriction completely preserves ischemic preconditioning in the aging heart. | Ischemic preconditioning (IP) has been proposed as an endogenous form of protection against ischemia reperfusion injury. IP, however, does not prevent post-ischemic dysfunction in the aging heart but may be partially corrected by exercise training and food restriction. We investigated the role of exercise training comb... |
2,320,696 | Fibroblast growth factor 2 mediated disruption of myelin-forming oligodendrocytes in vivo is associated with increased tau immunoreactivity. | We have previously shown that fibroblast growth factor 2 (FGF2) disrupts myelin formation by oligodendrocytes in vivo. Here, we have investigated the possibility that this is associated with changes in the expression of tau, a major microtubule-associated protein (MAP) involved in the production of myelin membranes by ... |
2,320,697 | Immunoreactivity for calcium-binding proteins defines subregions of the vestibular nuclear complex of the cat. | The vestibular nuclear complex (VNC) is classically divided into four nuclei on the basis of cytoarchitectonics. However, anatomical data on the distribution of afferents to the VNC and the distribution of cells of origin of different efferent pathways suggest a more complex internal organization. Immunoreactivity for ... |
2,320,698 | Malformations of cortical development: high-resolution MR and diffusion tensor imaging of fiber tracts at 3T. | Patients with malformations of cortical development and epilepsy may have a variety of abnormal brain findings, including abnormal gyral patterns, cortical thickening, decreased volume of white matter, and increased diffusion of white matter. The status of individual white matter fiber tracts, however, is unknown. We p... |
2,320,699 | MR quantitation of volume and diffusion changes in the developing brain. | Brain volume and diffusion change during maturation. Quantitation of these changes may be helpful in understanding normal brain development. We used diffusion-weighted imaging to characterize the volumetric and diffusion changes in vivo.</AbstractText>We recruited 30 pediatric volunteers (aged 1 month-17 years; 14 male... |
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