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2,322,000 | Multipolar migration: the third mode of radial neuronal migration in the developing cerebral cortex. | Two distinct modes of radial neuronal migration, locomotion and somal translocation, have been reported in the developing cerebral cortex. Although these two modes of migration have been well documented, the cortical intermediate zone contains abundant multipolar cells, and they do not resemble the cells migrating by l... |
2,322,001 | Endocrine status in patients with optic nerve hypoplasia: relationship to midline central nervous system abnormalities and appearance of the hypothalamic-pituitary axis on magnetic resonance imaging. | We here: 1) describe the phenotypic spectrum, including magnetic resonance imaging (MRI) appearances of the pituitary stalk and anterior and posterior pituitary [H-P (hypothalamic-pituitary) axis], in children with optic nerve hypoplasia (ONH) with or without an abnormal septum pellucidum (SP); and 2) define endocrine ... |
2,322,002 | Kv1.1 and Kv1.3 channels contribute to the delayed-rectifying K+ conductance in rat choroid plexus epithelial cells. | The choroid plexuses secrete, and maintain the composition of, the cerebrospinal fluid. K+ channels play an important role in these processes. In this study the molecular identity and properties of the delayed-rectifying K+ (Kv) conductance in rat choroid plexus epithelial cells were investigated. Whole cell K+ current... |
2,322,003 | Graded atmospheric oxygen level effects on performance and ascites incidence in broilers. | The effects of graded atmospheric O2 concentration (12, 14, 16, 18, and 20.6%) on chick performance and propensity to develop ascites were investigated using commercial male broilers. Chicks were housed in calorimetry chambers for 2 wk with incoming air diluted with N to provide the desired O2 concentration at thermone... |
2,322,004 | Surgical experience of 179 cases with craniopharyngiomas. | To retrospectively review 179 cases surgical treatments of craniopharyngiomas over a 7-year period, surgical experience as following.</AbstractText>Dependent on the locations of the tumors to the floor of the third ventricle, they were classified into the superior type of the third ventricle floor in which tumors grew ... |
2,322,005 | Normative values of 99mTc-MIBI distribution in myocardium in males and females, as a basis for quantitative planar scintigraphic method for detection of coronary artery disease in patients of both sexes. | Radionuclide perfusion studies of myocardium are being performed using planar and tomographic (SPECT) procedures. The latter method enables better detection as well as assessment of localisation and severity of scintigraphically visualised perfusion defects. On the other hand, lower cost of planar procedures using 99mT... |
2,322,006 | Effect of biventricular pacing on heart function evaluated by gated blood pool study in patients with end-stage heart failure. | Biventricular cardiac pacing has been used as a complementary form of therapy in patients with severe heart failure. The aim of this study was to evaluate the effect of the synchronous stimulation of both ventricles on the heart function measured by gated blood pool study (GBP).</AbstractText>Ten patients (9 men and 1 ... |
2,322,007 | Angiotensin converting enzyme and chymase activity in the feline heart and serum. | The feline cardiac and serum angiotensin converting enzyme (ACE) and chymase activities were determined and compared in dogs, and hamsters. In all three species, cardiac chymase activity exceeded ACE activity; however, there were some differences. In cats, left ventricular ACE and chymase activities (0.15 +/- 0.01 and ... |
2,322,008 | Mechanisms of cefadroxil uptake in the choroid plexus: studies in wild-type and PEPT2 knockout mice. | The choroid plexus uptake of [(3)H]cefadroxil was studied in peptide transporter 2 (PEPT2) wild-type and null mice as a function of temperature, transport inhibitors, pH, and saturability. At normal pH (7.4) and temperature (37 degrees C), the uptake of 1 microM cefadroxil was reduced by 83% in PEPT2(-/-) mice as compa... |
2,322,009 | Preservation of base-line hemodynamic function and loss of inducible cardioprotection in adult mice lacking protein kinase C epsilon. | Signaling pathways involving protein kinase C isozymes are modulators of cardiovascular development and response to injury. Protein kinase C epsilon activation in cardiac myocytes reduces necrosis caused by coronary artery disease. However, it is unclear whether protein kinase C epsilon function is required for normal ... |
2,322,010 | Calcium homeostasis in rat cardiomyocytes during chronic hypoxia: a time course study. | The present study determined Ca2+ handling in the hearts of rats subjected to chronic hypoxia (CH). Spectrofluorometry was used to measure intracellular Ca2+ concentration ([Ca2+]i) and its responses to electrical stimulation, caffeine, and isoproterenol in myocytes from the right ventricle of rats breathing 10% oxygen... |
2,322,011 | Cerebral ventricular size in developing normal kittens measured by ultrasonography. | To evaluate the age of fontanelle closure of normal kittens and the size of their lateral ventricles, 50 ultrasonographic examinations using the bregmatic fontanelle as an acoustic window were made. Seven kittens, laboratory animals, were included in the study. To verify the location of the lateral ventricle, two of th... |
2,322,012 | High field strength (4.7T) magnetic resonance imaging of hydrocephalus in an African Grey parrot (Psittacus erithacus). | Hydrocephalus was diagnosed in a juvenile African Grey parrot by high-field strength (4.7-Tesla) magnetic resonance imaging (MRI). Excellent anatomic detail was achieved, and there was severe dilation of all ventricles. Relative obstruction was localized to the level of or beyond the outflow of the fourth ventricle. Th... |
2,322,013 | Haemodynamic features during high-frequency oscillatory ventilation in preterms. | To compare the haemodynamic status during high-frequency oscillatory ventilation and conventional mechanical ventilation in very preterm infants with respiratory distress syndrome.</AbstractText>Thirty-two neonates of less than 30 wk gestation randomly assigned to high-frequency oscillatory ventilation (n = 15) or conv... |
2,322,014 | An approach to the three-dimensional display of left ventricular function and viability using MRI. | Cardiac MRI was performed in human volunteers to determine the magnitude of the misregistration (MSR) of cardiac landmarks due to variability in the diaphragm position for repeated breath-holds. Seven normal volunteers underwent MR imaging of the left ventricle (LV) to evaluate the magnitude of the endocardial centroid... |
2,322,015 | [Central and peripheral hemodynamics in patients with essential hypertension on a fasting diet]. | Effectiveness of an antihypertensive action of fasting therapy was studied in 147 patients with arterial hypertension stage I-II. Estimation of systolic and diastolic functions of the left ventricle in patients with arterial hypertension was carried out using stress echocardiography with isometric loading. Dynamics of ... |
2,322,016 | Isolation of neural stem cells from the forebrain of deceased early postnatal and adult rats with protracted post-mortem intervals. | Neural stem cells were isolated from deceased early postnatal and adult rats with varying post-mortem intervals. Animals were killed by deep anesthesia and stored in a refrigerator at 4 degrees C for 1-6 days before use. Neurospheres were obtained from the forebrain tissue, including the lateral ventricle in the early ... |
2,322,017 | Systemic insulin-like growth factor-I administration prevents cognitive impairment in diabetic rats, and brain IGF regulates learning/memory in normal adult rats. | Diabetic patients have impaired learning/memory, brain atrophy, and two-fold increased risk of dementia. The cause of cognitive disturbances that progress to dementia is unknown. Because neurotrophic insulin-like growth factor (IGF) levels are reduced in diabetic patients and rodents, and IGF can cross the blood-centra... |
2,322,018 | Phosphoinositide 3-kinase promotes adult subventricular neuroblast migration after stroke. | Rodent adult subventricular zone (SVZ)-derived progenitor cells abandon the rostral migratory stream (RMS)/olfactory complex postmiddle cerebral artery occlusion (MCAo) and migrate into compromised tissue, possibly playing a role in brain recovery. Using SVZ tissue explants from the adult rat, we investigated the role ... |
2,322,019 | Expression of stabilin-2, a novel fasciclin-like hyaluronan receptor protein, in murine sinusoidal endothelia, avascular tissues, and at solid/liquid interfaces. | Stabilin-2, the hepatic hyaluronan receptor, has recently been cloned by us. Together with stabilin-1, stabilin-2 constitutes a novel family of fasciclin-like hyaluronan receptor homologues. Here, we analyzed expression of stabilin-2 (mStab-2) in a broad array of C57BL/6 mouse organs and tissues. While northern blot an... |
2,322,020 | Morphology and ultrastructure of rat hippocampal formation after i.c.v. administration of N-acetyl-L-aspartyl-L-glutamate. | N-Acetyl-L-aspartyl-L-glutamate (NAAG) is one of the most abundant neuroactive compounds in the mammalian CNS. Our recent observations have suggested that NAAG administered into rat cerebral ventricles can cause neuronal death by apparently excitotoxic mechanisms that can be antagonized by the N-methyl-D-aspartate-rece... |
2,322,021 | Localization and function of the Na+/Ca2+-exchanger in normal and detubulated rat cardiomyocytes. | It is controversial whether the Na+/Ca2+-exchanger (NCX) can induce cardiomyocyte contraction through reverse-mode exchange and Ca2+-induced Ca2+ release (CICR). Information about the spatial distribution and functional activity within different sarcolemmal (SL) regions could shed light on this potential role. We raise... |
2,322,022 | Proximal upstream region of zebrafish bone morphogenetic protein 4 promoter directs heart expression of green fluorescent protein. | We examined the activity of the bone morphogenetic protein 4 (BMP4) promoter in zebrafish embryos via transient and stable transgenic expression analyses in order to obtain a better understanding of the regulation of BMP4 tissue-specific expression. Transient expression studies showed that the 9.0-kb BMP4 promoter/upst... |
2,322,023 | Liliequist membrane: three-dimensional constructive interference in steady state MR imaging. | To evaluate the Liliequist membrane in healthy volunteers by using three-dimensional (3D) Fourier transformation constructive interference in steady state (CISS) magnetic resonance (MR) imaging.</AbstractText>In 31 volunteers, the authors performed 3D CISS MR imaging. They divided the membrane into three segments: the ... |
2,322,024 | Association of depression duration with reduction of global cerebral gray matter volume in female patients with recurrent major depressive disorder. | The authors investigated the relationship between depression duration and cerebral gray matter volume in female patients with recurrent major depressive disorder.</AbstractText>Magnetic resonance imaging was used to measure intracranial and total brain volumes as well as gray matter and white matter volumes of the cere... |
2,322,025 | Relationship between plasma aldosterone and left ventricular structure and function in patients with essential hypertension. | Recent experimental studies demonstrated that elevation of plasma aldosterone is associated with an increased collagen accumulation resulting in myocardial fibrosis. The aim of this study was to evaluate the association of circulating aldosterone with cardiac structural and functional changes in patients with essential... |
2,322,026 | Spallanzani's mouse: a model of restoration and regeneration. | The ability to regenerate is thought to be a lost phenotype in mammals, though there are certainly sporadic examples of mammalian regeneration. Our laboratory has identified a strain of mouse, the MRL mouse, which has a unique capacity to heal complex tissue in an epimorphic fashion, i.e., to restore a damaged limb or ... |
2,322,027 | [Study of mechanism and the effect of intracerebroventricular microinjection of serotonin on gastric motility in rabbit]. | To explore the effect of central serotonin (5-hydroxytryptamine, 5-HT) on gastric motility in rabbit and to analysis its mechanism.</AbstractText>Intracerebroventricular (icv) microinjection of drugs were used. The frequency and the amplitude of contractions of gastric motility were recorded.</AbstractText>(1) Injectio... |
2,322,028 | Proposed guidelines for the diagnosis of canine idiopathic dilated cardiomyopathy. | Dilated cardiomyopathy (DCM) is a major cause of morbidity and mortality in various dog breeds. The diagnosis of overt DCM is not normally problematic, although the importance of active exclusion of other causes of the dilated, hypokinetic heart is emphasised. Recent interest in human familial DCM has prompted a number... |
2,322,029 | ROS are required for rapid reactivation of Na+/Ca2+ exchanger in hypoxic reoxygenated guinea pig ventricular myocytes. | The cardiac Na(+)/Ca(2+) exchanger (NCX) contributes to cellular injury during hypoxia, as its altered function is largely responsible for a rise in cytosolic Ca(2+) concentration ([Ca(2+)](i)). In addition, the NCX in guinea pig ventricular myocytes undergoes profound inhibition during hypoxia and rapid reactivation d... |
2,322,030 | Regulation of action potential duration under acute heat stress by I(K,ATP) and I(K1) in fish cardiac myocytes. | The mechanism underlying temperature-dependent shortening of action potential (AP) duration was examined in the fish (Carassius carassius L.) heart ventricle. Acute temperature change from +5 to +18 degrees C (heat stress) shortened AP duration from 2.8 +/- 0.3 to 1.3 +/- 0.1 s in intact ventricles. In 56% (18 of 32) o... |
2,322,031 | A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells. | The choroid plexus epithelium of the brain ventricular system produces the majority of the cerebrospinal fluid and thereby defines the ionic composition of the interstitial fluid in the brain. The transepithelial movement of Na+ and water in the choroid plexus depend on a yet-unidentified basolateral stilbene-sensitive... |
2,322,032 | Simultaneous hypersecretion of CSF and of brain interstitial fluid causes idiopathic intracranial hypertension. | Idiopathic intracranial hypertension (IdICH) is a high intracranial pressure and no evidence of intracranial lesions or hydrocephalus. The characteristics of IdICH and the anatomical and physiological data show that the mechanisms of elaboration of the interstitial fluid at blood-brain barrier (BBB) and of cerebrospina... |
2,322,033 | Idiopathic intracranial hypertension and idiopathic normal pressure hydrocephalus: diseases with opposite pathogenesis? | Idiopathic intracranial hypertension (IDICH) and idiopathic normal pressure hydrocephalus (IDNPH) are disorders of the circulation of the cerebrospinal fluid (CSF) with opposite diagnostic features, obscure etiology but the same treatment: CSF drainage. In both diseases a large quantity of CSF exists: equilibrated by t... |
2,322,034 | CNS melanocortin and leptin effects on stearoyl-CoA desaturase-1 and resistin expression. | The objective of this study was to determine whether centrally administered leptin decreased liver and adipose SCD1 expression or adipose resistin expression, and whether these effects were mediated by central melanocortin receptors. Male Sprague-Dawley rats were injected into the lateral cerebral ventricle (i.c.v.) on... |
2,322,035 | Familial Creutzfeldt-Jakob disease: a neuropsychological case study. | The spectrum of neuropsychological features of familial Creutzfeldt-Jakob disease (CJD) have seldom been reported, possibly because of (a) the rarity of this hereditary form of prion disease; (b) frequent delays in diagnosis, and; (c) the typically rapid demise of the patient, which affords little opportunity for compr... |
2,322,036 | Right ventricle of patients undergoing congenital cardiac surgery differentially expresses haem oxygenase-1 and heat shock protein 70 genes. | Reactive oxygen species are implicated in the pathogenesis of cardiac hypertrophy. Haem oxygenase-1 (HO-1), the rate-limiting enzyme in haem catabolism, is induced by oxidative stress and confers protection against oxidative tissue injuries. We used Northern blotting to examine expression of HO-1 and heat shock protein... |
2,322,037 | [Effect of hypoxic stress on the medullary arteries of the adrenal glands]. | It is known that suprarenal glands consist of two parts: cortex and medulla. Functional properties of circulation in these two parts are still unknown. This is a very important problem, but only a few studies have dealt with it, whereas full attention should be paid to the problem in future researches.</AbstractText>Th... |
2,322,038 | Regional atrophy in the brain of lissencephalic mouse lemur primates: measurement by automatic histogram-based segmentation of MR images. | Age-related regional cerebral atrophy was evaluated in a small lissencephalic primate, model of cerebral aging. Twelve mouse lemurs (Microcebus murinus), ages 1.9-10.9 years (maximum life span: 12 years), were studied. 3D inversion-recovery fast spin-echo MR images (isotropic resolution = 234 mum) were recorded at 4.7 ... |
2,322,039 | Theoretical and experimental study of growth and remodeling in the developing heart. | A theoretical model is presented for growth and remodeling in the developing embryonic heart. The model is a thick-walled tube composed of two layers of orthotropic pseudoelastic material. The analysis includes stress and strain dependent volumetric growth, with changes in material properties specified to reflect the e... |
2,322,040 | Mechanism of the positive contractile effect of nitric oxide on rat ventricular cardiomyocytes with positive force/frequency relationship. | The positive contractile effect of nitric oxide (NO) donors was studied on isolated rat ventricular cardiomyocytes within a range of a positive force/frequency relationship. We determined whether the observed effect depended on cGMP. The NO donors S-nitroso-acetyl-D,L-penicillamine (SNAP) and N-[4-[1-(3-aminopropyl)-2-... |
2,322,041 | [Brain natriuretic Peptide. Diagnostic and prognostic value in chronic heart failure]. | Brain natriuretic peptide (BNP) has been established as a new and reliable laboratory marker for chronic heart failure (CHF). BNP is a neurohormone secreted by the cardiac ventricles in response to volume expansion and pressure overload. It is released as N-terminal pro-brain natriuretic peptide and then Korrelaenzymat... |
2,322,042 | Feasibility of the fetal anatomic and maternal pelvic survey by magnetic resonance imaging at term. | This study was undertaken to determine which nonbiometric components of the American College of Obstetricians and Gynecologists recommended ultrasound fetal anatomic and maternal pelvic survey can be evaluated by fast acquisition magnetic resonance (MR) imaging in the term fetus.</AbstractText>Nonbiometric components o... |
2,322,043 | Neuropeptide Y administered into cerebral ventricles stimulates sucrose ingestion in the near-term ovine fetus. | In adults, nutrient intake is controlled by opposing actions of appetite stimulants (eg, neuropeptide Y [NPY]) and suppressors (eg, leptin). Because NPY may exert a preferential role in mediating adult carbohydrate intake, we sought to determine the effect of central NPY on near-term fetal carbohydrate ingestion.</Abst... |
2,322,044 | The discovery of the matrix cell, the identification of the multipotent neural stem cell and the development of the central nervous system. | In the early 1960s I applied 3H-thymidine autoradiography to the study of the cells constituting the neural tube, and found that its wall was composed solely of one kind of single-layered epithelial cell, which perform an elevator movement between the mitotic and DNA-synthetic zones in the wall in accord with the cell ... |
2,322,045 | Glia as neural progenitor cells. | Recent studies have substantially expanded our conception of the roles for glia in function and maintenance of the adult nervous system. Of these reports, several have re-examined the lineage relationships among neural stem cells, their early radial glial derivatives and their mitotically competent neurogenic daughters... |
2,322,046 | Ependymal tumors. | Ependymal tumors are rare malignancies that arise from the cells that line the ventricles and central canal of the spinal cord. Although they are more common in children, adults may also be effected by ependymal tumors. Prognosis is dependent on tumor location, histology, especially for myxopapillary tumors that tend t... |
2,322,047 | [Electrocardiography in cardiomyopathies]. | ECG plays a predominantly screening role in cardiomyopathies. It is particularly important in hypertrophic cardiomyopathies, where atrial abnormities may be present (25%), positive voltage criteria in hypertrophy of the left ventricle (63%), pathological Q or QS wave (24%), missing septal q in V5 and V6 (49%), missing ... |
2,322,048 | Nuclear expression of Survivin in paediatric ependymomas and choroid plexus tumours correlates with morphologic tumour grade. | Survivin is a gene that is widely expressed throughout the development of the normal mammalian embryo. Subcellular localisation of Survivin to both the nucleus and cytoplasm has suggested multiple functional roles, including inhibition of cell death, especially as demonstrated within a variety of malignant cell types, ... |
2,322,049 | The glial identity of neural stem cells. | Glia are the most numerous cells in the brain, and their many diverse functions highlight their essential role in the nervous system. Recent studies have revealed an unexpected new role for glia in a wide variety of species, that of stem cells/progenitors in the adult and embryonic brain. Differentiation along the glia... |
2,322,050 | Proteomics analysis of phosphotyrosyl-proteins in human lumbar cerebrospinal fluid. | Cerebrospinal fluid (CSF) is a secretion product of several different central nervous system (CNS) structures, including the choroid plexus in the ventricles. Pathological CNS processes are reflected in the protein composition of CSF. To elucidate the molecular events that occur in the homeostatic and pathological proc... |
2,322,051 | [A case of severe parkinsonism induced by failure of ventriculo-peritoneal shunt for aqueductal stenosis]. | A 26-year-old man, who had received a ventriculo-peritoneal shunt for obstructive hydrocephalus after possible encephalitis, complained of disturbance of upward gaze and difficulty in movement seven months after the shunt implantation. One month later, neurological examination revealed upward gaze paresis and rigidity ... |
2,322,052 | Ac-SDKP reverses cardiac fibrosis in rats with renovascular hypertension. | N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) is a natural substrate for the N-terminal active site of angiotensin-converting enzyme (ACE). We previously reported that Ac-SDKP prevented cardiac fibrosis in rats with renovascular or aldosterone-salt hypertension. However, it is not clear whether Ac-SDKP reverses cardi... |
2,322,053 | Na/Ca exchange and Na/K-ATPase function are equally concentrated in transverse tubules of rat ventricular myocytes. | Formamide-induced detubulation of rat ventricular myocytes was used to investigate the functional distribution of the Na/Ca exchanger (NCX) and Na/K-ATPase between the t-tubules and external sarcolemma. Detubulation resulted in a 32% decrease in cell capacitance, whereas cell volume was unchanged. Thus, the surface-to-... |
2,322,054 | Septo-optic dysplasia with congenital hepatic fibrosis. | This article reports a 7-year-old female with septo-optic dysplasia and congenital hepatic fibrosis. She manifested nystagmus and severe hepatosplenomegaly. Brain magnetic resonance imaging revealed agenesis of the septum pellucidum, optic nerve hypoplasia, pituitary gland stalk hypoplasia, and absence of the posterior... |
2,322,055 | Insights into the pathogenesis of cerebral lesions in incontinentia pigmenti. | We report the case of a neonate with incontinentia pigmenti and seizures on day 4 of life who underwent magnetic resonance imaging and angiography scanning at 8, 13, and 21 days of age. The serial magnetic resonance images demonstrated the evolution of acute microvascular hemorrhagic infarcts in the periventricular whi... |
2,322,056 | Endoscopic third ventriculostomy with cystoventricular stent placement in the management of dandy-walker malformation: technical case report of three patients. | Dandy-Walker malformation has conventionally been managed with placement of cystoperitoneal or ventriculoperitoneal shunts. However, associated aqueductal obstruction requires simultaneous drainage of both the supratentorial and infratentorial compartments.</AbstractText>Three children with Dandy-Walker malformation an... |
2,322,057 | Acute syringomyelia: case report. | Syringomyelia is generally regarded as a chronic, slowly progressive disorder. We describe a case of acute dilation of the central canal of the spinal cord that presented with rapidly progressive segmental signs.</AbstractText>A 29-year-old female patient who had previously undergone surgical treatment for a Chiari I m... |
2,322,058 | Green tea polyphenol (-)-epigallocatechin gallate prevents oxidative damage on periventricular white matter of infantile rats with hydrocephalus. | Hydrocephalus causes damage to periventricular white matter at least in part through chronic ischemia. Emphasizing the periventricular ischemia/hypoxia in hydrocephalus, various authors indicated the secondary biochemical impairment and oxidative damage in experimentally induced and congenital hydrocephalic rat brain. ... |
2,322,059 | Multiple left ventricular diverticula detected by second harmonic imaging: a case report. | A 51-year-old Japanese man was admitted to hospital for evaluation of anterior chest pain at rest. He had a past history of cerebellar infarction when he was 47 years old. A conventional 2-dimensional echocardiogram revealed normal left ventricular function, and no abnormal findings. However, second harmonic imaging de... |
2,322,060 | The impact of deafness to the survival of the newborn cells in the brain of juvenile white-rumped munia, Lonchura striata. | In white-rumped munia, early auditory experience is critical for normal song development. New neurons are constantly added to the telencephalon in juveniles. We examined the potential role of auditory experience in regulating the developmental changes in the song nuclei and the survival of newborn cells. We chose two s... |
2,322,061 | Visualization of erythrocytes in the zebrafish brain. | We found that erythrocytes of zebrafish have cytoplasmic peroxidase activity. Blood in the zebrafish brain was visualized using a standard peroxidase staining method after formaldehyde fixation. The erythrocytes in the brain were heavily stained, but neurons and glias were not stained at all. This easy method enables t... |
2,322,062 | A case of germinoma in the septum pellucidum manifesting as amnesia and hemiparesis. | We report a rare case of germinoma mainly located in the septum pellucidum.</AbstractText>A 19-year-old man presented with germinoma located in the septum pellucidum manifesting as amnesia and right hemiparesis. Magnetic resonance imaging demonstrated a heterogeneously enhanced mass in the septum pellucidum and abnorma... |
2,322,063 | Epidermoid cysts of the fourth ventricle: very long follow up in 9 cases and review of the literature. | This study reports late surgical results obtained in 9 patients operated on for an epidermoid cyst of the fourth ventricle. They represent 19/9% of all cases of epidermoids treated at our Department over a period of 25 years (1975-2000). 7 cases were diagnosed with CT and 2 cases with MR. Duration of clinical history r... |
2,322,064 | Prolonged cardiac dysfunction after withdrawal of chronic cocaine exposure in rats. | Cocaine abuse causes myocardial dysfunction and induces oxidative stress. However, the reversibility of these effects is unknown. We evaluated myocardial function and oxidative stress after cocaine withdrawal, in a rat model of chronic cocaine exposure. Standard echocardiography and Doppler tissue imaging were performe... |
2,322,065 | Effect of basic fibroblast growth factor treatment on brain progenitor cells after permanent focal ischemia in rats. | Intracisternal basic fibroblast growth factor (bFGF) enhances sensorimotor recovery after focal cerebral infarction in rats. One possible mechanism is stimulation of endogenous progenitor cells in brain. We investigated the effects of intracisternal bFGF on brain progenitor cells after stroke.</AbstractText>Proliferati... |
2,322,066 | Real-time monitoring of nitric oxide in ischemic myocardium using an NO-selective electrode calibrated by electron spin resonance. | Using a Langendorff-perfused rat heart preparation and selective electrodes, we determined nitric oxide (NO) and oxygen levels in cardiac tissue. An NO-selective electrode that was calibrated by electron spin resonance (ESR) spectroscopy was inserted into the middle of the myocardium in the left ventricle. Simultaneous... |
2,322,067 | Local force model for cardiac dynamics analysis from volumetric image sequences. | We propose a local force model based on the kinetics of the left ventricle (LV) surfaces to characterize the complex nonrigid motion that the heart undergoes. The left ventricle motion is analyzed in a coarse-to-fine fashion. First, global motion and deformation are analyzed and compensated with hierarchical surface mo... |
2,322,068 | Contractile effects of adenovirally-mediated increases in SERCA2a activity: a comparison between adult rat and rabbit ventricular myocytes. | Adenoviral vectors have been successfully used to increase the activity of the sarcoplasmic reticulum Ca(2+)-ATPase in adult ventricular myocytes and to produce functional improvements in contractility in vivo and in vitro. While in vivo experiments are often performed in rat, in vitro manipulation of myocytes has been... |
2,322,069 | Cellular mechanisms involved in the stenosis and obliteration of the cerebral aqueduct of hyh mutant mice developing congenital hydrocephalus. | Two phases may be recognized in the development of congenital hydrocephalus in the hyh mutant mouse. During embryonic life the detachment of the ventral ependyma is followed by a moderate hydrocephalus. During the first postnatal week the cerebral aqueduct becomes obliterated and a severe hydrocephalus develops. The ai... |
2,322,070 | Transient expression of doublecortin during adult neurogenesis. | During development of the central nervous system, expression of the microtubule binding protein doublecortin (DCX) is associated with migration of neuroblasts. In addition to this developmental role, expression of DCX remains high within certain areas of the adult mammalian brain. These areas, mainly the dentate gyrus ... |
2,322,071 | A second Leonardo da Vinci? | We describe a young woman who suddenly began mirror writing with her right hand and has not reverted to normal writing for more than 6 years, although she writes normally with her left hand. She is ambidextrous, although she had previously used only her right hand for writing and drawing. Since it is much easier for he... |
2,322,072 | [Study on establishment of Alzheimer's disease animal model and intervening effect of zhinao capsule on it]. | To establish an experimental animal model of Alzheimer's disease (AD) with clinical and pathological specificity conformed to AD in human, and to observe the effect of Zhinao Capsule (ZNC) on learning, memory and patho-morphological parameters in the model.</AbstractText>The experimental AD model of rats was improved a... |
2,322,073 | White matter damage and intraventricular hemorrhage in very preterm infants: the EPIPAGE study. | To evaluate the prevalence of cranial ultrasound abnormalities in very preterm infants as a function of gestational age, plurality, intrauterine growth restriction, and death before discharge.</AbstractText>A prospective, population-based cohort of 2667 infants born between 22 and 32 weeks of gestation in 1997 in nine ... |
2,322,074 | Constitutive expression of various xenobiotic and endobiotic transporter mRNAs in the choroid plexus of rats. | The aim of this study was to quantitatively determine the constitutive expression levels of various transporter mRNAs in rat choroid plexus. To provide a reference for the relative expression levels, the expression of various transporter mRNAs in choroid plexus were compared with that in liver, kidney, and ileum. The m... |
2,322,075 | [Frontal dementia or dementia praecox? A case report of a psychotic disorder with a severe decline]. | Many authors have described these last years the difficulty to establish a differential diagnosis between schizophrenia and frontotemporal dementia. However treatment and prognosis of these two separate diseases are not the same. Schizophrenia is a chronic syndrome with an early onset during teenage or young adulthood ... |
2,322,076 | Sudden death secondary to delayed closure of endoscopic third ventriculostomy. | An 11-year-old boy who underwent an initially successful endoscopic third ventriculostomy (ETV) died 4 months later secondary to acute hydrocephalus. This is the first report of sudden death caused by delayed closure of ETV. Guidelines to patients, parents and primary caregivers should include the possibility of ETV fa... |
2,322,077 | Changes in the size of the lateral ventricles in the normal-term newborn following vaginal delivery. | This is a study of the size of the lateral ventricles in a population of normal-term newborns following vaginal delivery.</AbstractText>To assess the time course for the lateral ventricles to change from closed to open following vaginal delivery.</AbstractText>A total of 143 normal-term newborns had a videotaped crania... |
2,322,078 | Cardiac natriuretic peptides:a proteomic window to cardiac function and clinical management. | Congestive heart failure (CHF) is a leading cause of adult hospitalization in the United States, and despite advancements in treatment, the disease remains a major clinical challenge. The chief symptom of CHF is dyspnea, but in the urgent-care setting, it is often difficult to distinguish between cardiac and pulmonary ... |
2,322,079 | Phosphoinositide 3-kinase regulates excitation-contraction coupling in neonatal cardiomyocytes. | The phosphoinositide 3-kinase (PI3K) inhibitor LY-294002 decreased steady-state contraction in neonatal rat ventricular myocytes (NRVM). To determine whether the effect on steady-state contraction could be due to decreased intracellular Ca(2+) content, Ca(2+) content was assessed with fluorescent plate reader analysis ... |
2,322,080 | Effect of irradiation on enzymes of the capillary bed in rat ventricles. | The effect of localized irradiation on the enzyme activity in rat cardiac capillaries was examined in experiments in which the arteriolar and venular portions of the capillary bed were distinguished by the double-staining method. This method shows that the endothelial cells of the former contain alkaline phosphatase (A... |
2,322,081 | Deformable biomechanical models: application to 4D cardiac image analysis. | This article describes a methodology for creating a generic volumetric biomechanical model from different image modalities and segmenting time series of medical images using this model. The construction of such a generic model consists of three stages: geometric meshing, non-rigid deformation of the mesh in images of v... |
2,322,082 | Supratentorial arachnoid cyst mimicking a Ménière's disease attack. | Arachnoid cysts (AC) often present with symptoms depending on their anatomical location within the skull; while supratentorial cysts grow causing relatively few symptoms, infratentorial ones may impair liquor circulation at the level of the fourth ventricle, giving rise to intracranial hypertension, or may stretch the ... |
2,322,083 | Noninvasive imaging of cardiac transmembrane potentials within three-dimensional myocardium by means of a realistic geometry anisotropic heart model. | We have developed a new approach for imaging cardiac transmembrane potentials (TMPs) within the three-dimensional (3-D) myocardium by means of an anisotropic heart model. The cardiac TMP distribution is estimated from body surface electrocardiograms by minimizing objective functions of the "measured" body surface poten... |
2,322,084 | [Neuroimaging and clinical manifestations of herpes simplex encephalitis in children]. | Mortality rates in herpes simplex encephalitis are still high because the condition is diagnosed too late and so specific treatment is delayed. We present a retrospective study of patients with herpes encephalitis. If in a pediatric patient with CNS infection MR images show high intensity signal lesions in characterist... |
2,322,085 | [Neuroimaging in Lyme disease]. | Imaging techniques are commonly used in the diagnostics of the central nervous system disorders. Abnormalities found using MRI and MRS in neuroborreliosis patients are described. |
2,322,086 | Meningeal melanocytoma: an aggressive course for a benign tumor. | A 79-year-old female presented with difficulty ambulating and was found to have weakness and hyperreflexia in the lower extremities. Magnetic resonance imaging (MRI) revealed a large T8-T9 intraspinal tumor. She underwent a thoracic laminectomy, and excision of an intradural extramedullary lesion. The surgical specimen... |
2,322,087 | [Own experience in surgical treatment of the pineal region and midbrain tumors via the infratentorial approach]. | Nine cases of tumours located in the pineal and midbrain region in adults operated on between November 1998 and July 2002 in Dept. of Neurosurgery, Central Military Hospital in Warsaw are reported. The patients (2 men and 7 women) were aged from 27 and 69 years (mean age 43.6 years). Their main initial symptoms were ca... |
2,322,088 | [Changes in head circumference and ventricular system size after neuro-endoscopic third ventriculostomy in children]. | The aim of the study was to compare changes in the head circumference ventricular system size after neuroendoscopic third ventriculostomy with those following shunt implantation in children suffering from chronic hydrocephalus. The data were analysed to establish criteria of success of neuroendoscopic procedures. In th... |
2,322,089 | Intracranial hemorrhage progressing to porencephaly as a result of congenitally acquired cytomegalovirus infection--an illustrative report. | To report ultrasound and magnetic resonance imaging (MRI) findings in a fetus with intracranial hemorrhage and porencephaly, presumed secondary to intrauterine cytomegalovirus (CMV) infection.</AbstractText>A 20-year-old, G2, P1 woman presented at 28.6 weeks' gestation after ultrasound examination demonstrated apparent... |
2,322,090 | Prenatal diagnosis of cavum velum interpositum cysts: significance and outcome. | To describe a fetal cavum velum interpositum cyst (CVIC) and to review its clinical significance.</AbstractText>Description and follow-up of two cases with prenatal diagnosis of a midline cyst in the fetal brain, at the Chaim Sheba Medical Center. The cases were reviewed and followed-up by a multidisciplinary team that... |
2,322,091 | Hypothalamic response to experimental allergic encephalomyelitis: role of substance P. | Adjuvant-induced arthritis (AA) is thought to be a model for experimental chronic stress that has as main features decreased adrenocorticotropin hormone (ACTH) plasma levels and a rise in median eminence content of arginine vasopressin (AVP) due to the activity of substance P. In experimental allergic encephalomyelitis... |
2,322,092 | Adiposity contributes to differences in left ventricular structure and diastolic function with age in healthy men. | We sought to examine the influence of adiposity in age-associated changes in the left ventricle (LV) in a cohort of 113 healthy men, aged 20-79 yr, by measuring LV structure and diastolic function (echocardiography), whole body composition, and regional adiposity (dual energy x-ray absorptiometry). Aging was associated... |
2,322,093 | Association of morphological characteristics with precocious puberty and/or gelastic seizures in hypothalamic hamartoma. | The pathogenesis of central precocious puberty (PP) and/or gelastic seizures due to a hypothalamic hamartoma (HH) is still under debate. We evaluated the association of clinical symptoms with morphology and localization of the HH in 34 patients. The majority (86.4%) of HHs in patients with isolated PP (n = 22; 68.2% fe... |
2,322,094 | Effects of delayed preconditioning on myocardial regional contractility during repeated episodes of low-flow ischaemia in anaesthetized dogs: possible role of nitric oxide. | The effect of cardiac pacing on repeated low-flow ischaemia-induced changes in regional myocardial segmental contractility, and the role in these changes of nitric oxide, were investigated in anaesthetized dogs. Dogs were instrumented for cardiac pacing (pacing electrode in the right ventricle). Dogs were paced (four t... |
2,322,095 | A hyperpolarization activated inward current (If) is present in infant ventricular myocytes. | I(f) was shown to be present in adult human atrial and ventricular myocytes but data obtained from infant myocytes are lacking. We have studied I(f) in isolated ventricular myocytes from children undergoing surgical correction of tetralogy of Fallot (TOF; n = 5; mean age: 15.3 months). All recordings were made with the... |
2,322,096 | A role for nitric oxide in hypoxia-induced activation of cardiac KATP channels in goldfish (Carassius auratus). | Hypoxia-induced shortening of cardiac action potential duration (APD) has been attributed in mammalian hearts to the activation of ATP-sensitive potassium (KATP) channels. Since KATP channels are also present at high densities in the hearts of vertebrate ectotherms, speculation arises as to their function during period... |
2,322,097 | Improvement of neurological deficits by intracerebral transplantation of human adipose tissue-derived stromal cells after cerebral ischemia in rats. | Mesenchymal stem cells can be expanded rapidly in vitro and differentiated into multiple mesodermal cell types. In addition, their differentiation into neuron-like cells expressing markers typical for mature neurons has been reported. We isolated human adipose tissue stromal cells (hATSCs) from human liposuction tissue... |
2,322,098 | Endogenous and exogenous ciliary neurotrophic factor enhances forebrain neurogenesis in adult mice. | Neurogenesis in the adult mammalian CNS occurs in the subventricular zone (SVZ) and dentate gyrus. The receptor for ciliary neurotrophic factor (CNTF), CNTFRalpha, is expressed in the adult subventricular zone. Because the in vitro effects of CNTF on neural precursors have been varied, including proliferation and diffe... |
2,322,099 | alpha6beta1 integrin directs migration of neuronal precursors in adult mouse forebrain. | New neuroblasts are constantly generated in the adult mammalian subventricular zone (SVZ) and migrate via the very-restricted rostral migratory stream (RMS) to the olfactory bulb, where they differentiate into functional neurons. Several facilitating and repulsive molecules for this migration have been identified, but ... |
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