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2,324,000 | Intravenous administration of human umbilical cord blood cells in an animal model of MPS III B. | Sanfilippo syndrome type B (MPS III B) is caused by a deficiency of alpha-N-acetylglucosaminidase enzyme (Naglu), leading to accumulation of heparan sulfate (HS), a glycosaminoglycan (GAG), within lysosomes and to eventual progressive cerebral and systemic multiple organ abnormalities. Treatment of MPS patients is main... |
2,324,001 | Beam hardening correction in CT myocardial perfusion measurement. | This paper presents a method for correcting beam hardening (BH) in cardiac CT perfusion imaging. The proposed algorithm works with reconstructed images instead of projection data. It applies thresholds to separate low (soft tissue) and high (bone and contrast) attenuating material in a CT image. The BH error in each pr... |
2,324,002 | Intracranial pressure waveform analysis during rest and suctioning. | Cerebral compliance is a measure of cerebral adaptability to increases in volume within the intracranial space and an indicator of risk for neurological deterioration. However, no direct measurement of compliance exists in clinical practice to guide nursing care or treatment decisions. Current use of mean intracranial ... |
2,324,003 | Multi-contrast large deformation diffeomorphic metric mapping for diffusion tensor imaging. | Diffusion tensor imaging (DTI) can reveal detailed white matter anatomy and has the potential to detect abnormalities in specific white matter structures. Such detection and quantification are, however, not straightforward. The voxel-based analysis after image normalization is one of the most widely used methods for qu... |
2,324,004 | Analysis of ventricular hypertrabeculation and noncompaction using genetically engineered mouse models. | Ventricular trabeculation and compaction are two of the many essential steps for generating a functionally competent ventricular wall. A significant reduction in trabeculation is usually associated with ventricular compact zone deficiencies (hypoplastic wall), which commonly lead to embryonic heart failure and early em... |
2,324,005 | Glutathione homeostasis in ventricular myocytes from rat hearts with chronic myocardial infarction. | The ubiquitous tripeptide glutathione (GSH) is an essential factor in many biological processes, thus its depletion has a major impact on cell function and survival. In this study, we examined regulation of GSH in cardiomyocytes under chronic oxidative stress elicited by myocardial infarction (MI). Cardiac dysfunction ... |
2,324,006 | Distinct phases of cardiomyocyte differentiation regulate growth of the zebrafish heart. | Amongst animal species, there is enormous variation in the size and complexity of the heart, ranging from the simple one-chambered heart of Ciona intestinalis to the complex four-chambered heart of lunged animals. To address possible mechanisms for the evolutionary adaptation of heart size, we studied how growth of the... |
2,324,007 | The effects of heavy long-term exercise on ventricular myocyte shortening and intracellular Ca2+ in streptozotocin-induced diabetic rat. | This study investigated whether exercise training, initiated at the onset of diabetes, could preserve the contractile properties of ventricular myocytes.</AbstractText>The effects of a heavy exercise training program on shortening and intracellular Ca(2+) in unloaded ventricular myocytes from streptozotocin (STZ)-induc... |
2,324,008 | [CT and MR brain imaging following hemispherotomy]. | The aim of the study was to define the usual and pathological modifications arising in the brain following hemispherotomy for intractable epilepsy in children.</AbstractText>Preoperative MRI and postoperative imaging scans (CT in the first week, MRI at 3 months and 1 year after surgery) were reviewed in a series of 52 ... |
2,324,009 | High-frequency chirp ultrasound imaging with an annular array for ophthalmologic and small-animal imaging. | High-frequency ultrasound (HFU, >20 MHz) is an attractive means of obtaining fine-resolution images of biological tissues for ophthalmologic, dermatological and small-animal imaging applications. Even with current improvements in circuit designs and high-frequency equipment, HFU has two inherent limitations. First, ... |
2,324,010 | Sequencing and cardiac expression of Apelin in Sus Scrofa. | In humans, the Apelin gene is located on chromosome Xq25-26.1 and it encodes a 77-aminoacid prepropeptide. Considerable sequence homology exists across different mammalian species. Apelin is emerging as an important regulator of cardiovascular homeostasis but, at present, few data from humans are available and further ... |
2,324,011 | Reduced glutathione is highly expressed in white matter and neurons in the unperturbed mouse brain--implications for oxidative stress associated with neurodegeneration. | Oxidative stress is implicated in the pathogenesis of many neurodegenerative diseases, including Parkinson's disease and Alzheimer's disease. The depletion of glutathione (GSH) a powerful antioxidant renders cells particularly vulnerable to oxidative stress. Isolated neuronal and glial cell culture studies suggest that... |
2,324,012 | [Structural and functional neuroanatomy of attention-deficit hyperactivity disorder (ADHD)]. | Attention-deficit hyperactivity disorder (ADHD) is a common and impairing neuropsychiatric disorder with preschool onset. ADHD occurs in approximately 3-9% of the childhood population. There is a much higher incidence rate in boys who are around three times more likely than girls to be diagnosed. Approximately 30-60% o... |
2,324,013 | Aquaporin-4 maintains ependymal integrity in adult mice. | Ependymal cells form the walls of the ventricles, and take part in the production of cerebrospinal fluid (CSF). Aquaporin-4 (AQP4), a predominant water channel of the brain, is restricted to basolateral plasma membranes of ependymal cells. The highly polarized expression of AQP4 suggests it may be involved in maintaini... |
2,324,014 | No volume difference of medulla oblongata between young and old Korean people. | The purpose of this study was to determine the effects of aging and gender on the volumes of total brain, brainstem, cerebellum and lateral ventricle of healthy Koreans by magnetic resonance imaging (MRI). Using three-dimensional MRI volumetry, we compared the volumes of various brain regions according to age and gende... |
2,324,015 | A model of ischemia-induced neuroblast activation in the adult subventricular zone. | We have developed a rat brain organotypic culture model, in which tissue slices contain cortex-subventricular zone-striatum regions, to model neuroblast activity in response to in vitro ischemia. Neuroblast activation has been described in terms of two main parameters, proliferation and migration from the subventricula... |
2,324,016 | Hypothalamic reactive oxygen species are required for insulin-induced food intake inhibition: an NADPH oxidase-dependent mechanism. | Insulin plays an important role in the hypothalamic control of energy balance, especially by reducing food intake. Emerging data point to a pivotal role of reactive oxygen species (ROS) in energy homeostasis regulation, but their involvement in the anorexigenic effect of insulin is unknown. Furthermore, ROS signal deri... |
2,324,017 | Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo. | The polycomb gene Bmi-1 is required for the self-renewal of stem cells from diverse tissues, including the central nervous system (CNS). Bmi-1 expression is elevated in most human gliomas, irrespective of grade, raising the question of whether Bmi-1 over-expression is sufficient to promote self-renewal or tumorigenesis... |
2,324,018 | Ethanol teratogenesis in five inbred strains of mice. | Previous studies have demonstrated individual differences in susceptibility to the detrimental effects of prenatal ethanol exposure. Many factors, including genetic differences, have been shown to play a role in susceptibility and resistance, but few studies have investigated the range of genetic variation in rodent mo... |
2,324,019 | Heterologous hybridization to a complementary DNA microarray reveals the effect of thermal acclimation in the endothermic bluefin tuna (Thunnus orientalis). | The temperature stress that pelagic fishes experience can induce physiological and behavioural changes that leave a signature in gene expression profiles. We used a functional genomics approach to identify genes that were up- or down-regulated following thermal stress in the Pacific bluefin tuna. Following the acclimat... |
2,324,020 | Intraventricular metaplastic meningioma in a child: case report and review of the literature. | Childhood meningiomas are rare and display important differences from adult forms. We report the first case of an intraventricular metaplastic meningioma arising in a child. A 7-year-old female underwent resection of an enhancing tumor arising within the left lateral ventricle. It was composed of monomorphic cells embe... |
2,324,021 | Comparison of exercise-rest-reinjection Tl-201 imaging and rest sublingual isosorbide dinitrate Tc-99m MIBI imaging for the assessment of myocardial viability. | Nitrate administration has been proposed to enhance the detection of myocardial viability when performing myocardial perfusion imaging. In this study, we aimed to compare Tl-201 exercise-rest-reinjection protocol with rest isosorbide dinitrate (ISDN)-Tc99m MIBI study in the same population examined for the myocardial v... |
2,324,022 | Microscope and endoscopic pituitary surgery. | Having just celebrated the centenary of the first transsphenoidal pituitary operation by (Schloffer in Austria in Beitr Klin Chir 50:767-817, 1906), and this year the quarter centenary of the first published report of a therapeutic use of the neuroendoscope (for colloid cysts of the third ventricle) (Powell et al. in N... |
2,324,023 | Arachnoid cysts of the fourth ventricle - short illustrated review. | Arachnoid cysts are frequent anomalies of the CNS. They are benign lesions within the arachnoid membrane and have been reported to occur in virtually all locations where arachnoid is present. An intraventricular location, however, is rare and occurrence within the fourth ventricle is particularly uncommon. The first re... |
2,324,024 | Occipital inter-hemispheric approach for lateral ventricular trigone meningioma. | The optimal surgical approach for a trigone meningioma is still controversial. Here, we report two patients with trigone meningioma treated successfully via an occipital inter-hemispheric and trans-cortical approach in the lateral semi-prone position.</AbstractText>A 53-year-old woman was admitted to a local hospital w... |
2,324,025 | Targeting activated microglia in Alzheimer's pathology by intraventricular delivery of a phagocytosable MRI contrast agent in APP23 transgenic mice. | The role of phagocytosing immune cells in Alzheimer's pathology can be studied experimentally in APP23 transgenic mice. This present study intended to label phagocytosing immune cells in the plaque periphery of APP23 mice in vivo by intraventricular injection of VSOP-C184, a phagocytosable iron oxide nanoparticle MRI c... |
2,324,026 | ABCB1 is predominantly expressed in human fetal neural stem/progenitor cells at an early development stage. | ABCB1 is a human ABC transporter originally characterized by its ability to cause resistance to chemotherapy drugs in cancer cells, and later found to be functionally expressed in human neural stem/progenitor cells (NSPCs) in vitro. Here, we performed a detailed examination of ABCB1's expression on human NSPCs in vitro... |
2,324,027 | Potential of choroid plexus epithelial cell grafts for neuroprotection in Huntington's disease: what remains before considering clinical trials. | The choroid plexuses (CPs) help maintain the extracellular milieu of the brain by modulating chemical exchange between the cerebrospinal fluid and brain parenchyma, surveying the chemical and immunological status of the brain, detoxifying the brain, secreting a nutritive "cocktail" of polypeptides, and participating in... |
2,324,028 | Investigation on the structure of ventricular mass using magnetic resonance diffusion tensor imaging. | The 3-dimensional arrangement of the ventricular mass remains controversial. In this study, we used magnetic resonance diffusion tensor imaging (MRDTI) in an attempt to determine whether the ventricular mass is arranged in the form of a helical ventricular myocardial band (HVMB) and what the geometrical features of the... |
2,324,029 | Three-dimensional imaging of a comma-shaped right ventricular hydatid cyst. | We report herein a hydatid cyst of the right ventricle and its two- and three-dimensional echocardiographic appearance. |
2,324,030 | Role of central calcitonin gene-related peptide (CGRP) in locomotor and anxiety- and depression-like behaviors in two mouse strains exhibiting a CGRP-dependent difference in thermal pain sensitivity. | We have previously shown that, in AKR and C57BL/6 mice, a genetic polymorphism results in differential expression of the peptide, calcitonin gene-related polypeptide (CGRP), explaining a strain difference in thermal pain sensitivity. Although CGRP is widely distributed in the brain, little is known about the effects of... |
2,324,031 | The potential role of nitric oxide synthase in survival and regeneration of magnocellular neurons of hypothalamo-neurohypophyseal system. | Previous investigations from this laboratory have demonstrated that hypophysectomy induces up-regulation of neuronal nitric oxide synthase (nNOS) in magnocellular neurons of the mammalian hypothalamo-neurohypophyseal system (HNS). Accompanied by this upregulation of nNOS, both neuronal regeneration and degeneration are... |
2,324,032 | Early surgical management of antenatal diagnosed cystic lesions of the foramen of Monro causing monoventricular hydrocephalus. | After diagnosis of an antenatal monoventricular hydrocephalus caused by a cystic lesion of the foramen of Monro, treatment modality and time frame may be difficult to assess. Previously, this type of hydrocephalus was often treated with internal shunting. The advent of neuroendoscopy has changed the surgical management... |
2,324,033 | MRI of pneumorachis in a newborn infant with open myelomeningocele. | Pneumorachis, or air within the spinal canal, is a very rare radiographic finding, frequently of traumatic origin. A newborn infant with an open lumbosacral myelomeningocele presented with severe paraparesis and an unexpected dysfunction of the brainstem with somnolence, irregular respiration, and motor deficits of the... |
2,324,034 | Visual field deficit due to downward displacement of optic chiasm. | Visual disturbance in hydrocephalus is typically due to raised intracranial pressure. We describe a patient who presented with marked loss of peripheral visual fields, but without features suggestive of raised intracranial pressure. MR scan showed an enlarged third ventricle and a downward displacement of the optic chi... |
2,324,035 | Systemic hypertension and the right-sided cardiovascular system: a review of the available evidence. | Abnormal vasoconstriction of the lesser circulation characterizes a subset of patients with essential hypertension, a possible effect of mechanisms, such as enhanced sympathetic tone, increased delivery of blood-borne vasoconstrictor substances or abnormal local release of vasoactive factors, acting on both sides of th... |
2,324,036 | Nerve growth factor and its receptors TrkA and p75 are upregulated in the brain of mdx dystrophic mouse. | Increased angiogenesis and an altered blood-brain barrier have been reported in the brain of dystrophin-deficient mdx mouse, an experimental model of Duchenne muscular dystrophy. To further elucidate the mechanisms underlying angiogenesis in Duchenne muscular dystrophy, in this study we evaluated whether nerve growth f... |
2,324,037 | Chemotherapeutic drug transport to brain tumor. | Implantation of polymeric wafers to deliver a chemotherapeutic drug is the most popular strategy against a brain tumor, but the understanding on local drug transport to influence the treatment efficacy is often overlooked. In this work, we employ a computational fluid dynamics simulation to study the suitability of fou... |
2,324,038 | Effects of the LHRH antagonist Cetrorelix on the brain function in mice. | The decapeptide Cetrorelix, an LHRH antagonist, inhibits gonadotropin and sex steroid secretion. Cetrorelix is used for IVF-ET procedures and for the treatment of patients with prostate carcinoma, benign prostatic hyperplasia, endometriosis, leiomyomas and, ovarian cancer. However little is known about the effects of C... |
2,324,039 | Brain insulin infusion does not augment the counterregulatory response to hypoglycemia or glucoprivation. | Although high dosages of insulin can cause hypoglycemia, several studies suggest that increased insulin action in the head may paradoxically protect against severe hypoglycemia by augmenting the sympathoadrenal response to hypoglycemia. We hypothesized that a direct infusion of insulin into the third ventricle and/or t... |
2,324,040 | Emergency transorbital ventricular puncture: refinement of external landmarks. | Emergency access to the ventricular system is sometimes necessary for the treatment of raised intracranial pressure with ensuing herniation. One procedure described in the literature is a transorbital approach performed using a spinal needle. Because past publications have been case reports with minimal definition of e... |
2,324,041 | Evaluation of the chronic complications of diabetes in a high fructose diet in rats. | The increasing prevalence of type 2 diabetes is associated with increasing health costs, especially for the treatment of cardiovascular disease. The development of new treatment modalities requires animal models that mimic the range of pathophysiological changes seen in diabetic humans. Dietary fructose intake has been... |
2,324,042 | Normal and hydrocephalic brain dynamics: the role of reduced cerebrospinal fluid reabsorption in ventricular enlargement. | CINE phase-contrast MRI (CINE-MRI) was used to measure cerebrospinal fluid (CSF) velocities and flow rates in the brain of six normal subjects and five patients with communicating hydrocephalus. Mathematical brain models were created using the MRI images of normal subjects and hydrocephalic patients. In our model, the ... |
2,324,043 | Amygdala volume and verbal memory performance in schizophrenia and bipolar disorder. | To clarify the relationship between amygdala-hippocampal volume and cognitive performance in schizophrenia and bipolar disorder.</AbstractText>Abnormalities of the amygdala-hippocampal complex and memory deficits have been reported in both schizophrenia and bipolar illness.</AbstractText>We examined memory performance ... |
2,324,044 | Oxidative-nitrosative stress in a rabbit pup model of germinal matrix hemorrhage: role of NAD(P)H oxidase. | Germinal matrix hemorrhage-intraventricular hemorrhage is the most common neurological problem of premature infants. Despite this, mechanisms of brain injury from intraventricular hemorrhage are elusive. We hypothesized that germinal matrix hemorrhage-intraventricular hemorrhage, by induction of NAD(P)H oxidases, might... |
2,324,045 | Transforming growth factor-beta1 induces matrix metalloproteinase-9 expression in human meningeal cells via ERK and Smad pathways. | Transforming growth factor (TGF)-beta1, a cytokine released into the cerebrospinal fluid (CSF) after intraventricular hemorrhage (IVH), stimulates the expression of the components of the extracellular matrix (ECM), which causes progressive ventricular dilatation by impaired CSF absorption. Matrix metalloproteinase-9 (M... |
2,324,046 | Primary central nervous system vasculitis mimicking brain tumour: case report and literature review. | Primary central nervous system vasculitis (PCNSV) is a rare inflammatory disease causing significant morbidity and mortality. We present a detailed history and clinical course of a patient with PCNSV along with a literature review. A 50-year-old Chinese female presented with a 6-month history of mild to moderate headac... |
2,324,047 | Heat loss during exercise is related to serotonin activity in the preoptic area. | To investigate the influence of the central cholinergic system on thermoregulation and brain serotonin concentration during exercise; 2 microl of physostigmine (5x10 M) or saline solution was injected into the lateral cerebral ventricle of running rats. At fatigue, brains were quickly removed and serotonin and 5-hydrox... |
2,324,048 | Histopathophysiological comparison of male and female heart tissue following sustained release of supraphysiological levels of corticosteroid - biomed 2009. | Chronic stress results in elevated cortisol levels, which is associated with known physiological abnormalities such as hypertension, insulin resistance, and higher incidence of cardiovascular events. The onset of adverse cardiovascular events differs between males and females, and it is generally reported that stress a... |
2,324,049 | [Repolarization pattern of the ventricular myocardium in pikes]. | The study aimed at investigation into the repolarization pattern in the myocardium of fish. Activation times, activation-recovery intervals and repolarization times were determined in the intramural layers of the heart ventricle in eight pikes with multiple plunge electrodes. In the heart ventricle of the pike, the ear... |
2,324,050 | Surgical anatomy and surgical approaches to the lateral ventricles. | This study focuses on the surgical approaches to intraventricular tumors which have developed within the cavity of the lateral ventricle. The first section is dedicated to embryology and describes the wrapping of the telencephalic vesicles around the thalamus and the morphogenesis of basal nuclei and commissures. In th... |
2,324,051 | Rac is involved in the interkinetic nuclear migration of cortical progenitor cells. | The small GTPase Rac regulates neuronal behavior, but whether it also functions in neural progenitor cells has not yet been explored. Here we report that Rac contributes to the regulation of nuclear migration in neocortical progenitor cells. Rac1 is expressed by progenitor cells in a unique spatiotemporal pattern. Cros... |
2,324,052 | Quantitative magnetic resonance and optical imaging biomarkers of melanoma metastatic potential. | Noninvasive or minimally invasive prediction of tumor metastatic potential would facilitate individualized cancer management. Studies were performed on a panel of human melanoma xenografts that spanned the full range of metastatic potential measured by an in vivo lung colony assay and an in vitro membrane invasion cult... |
2,324,053 | Subacute perforation of the St. Jude Riata implantable cardioverter-defibrillator lead: a report of two pediatric cases. | The Medtronic Riata implantable cardioverter-defibrillator (ICD) lead is a 7-Fr ICD lead shown to have a propensity for cardiac perforation. This report details two pediatric cases of cardiac perforation in patients with a Riata ICD lead. Analysis regarding the effect of ICD implantation techniques on cardiac perforati... |
2,324,054 | Fluorescence and electron microscopic localization of F-actin in the ependymocytes. | The organization of F-actin in the ventricular system has been reported to display pronounced regional differences with respect to shape, size, and development. However, the real roles played by F-actin in these cells cannot be understood unless the precise localization of F-actin is defined. In the present study, we u... |
2,324,055 | [Transthyretin: it's miracle function and pathogenesis]. | Transthyretin (TTR) was previously called prealbumin because the band it formed on agarose gel electrophoresis at pH 8.6 was at the prealbumin position. However, it has been well documented that TTR of rodents does not show a prealbumin position on electrophoresis. Now, its name describes its function, binding to retin... |
2,324,056 | Conditional ablation and recovery of forebrain neurogenesis in the mouse. | Forebrain neurogenesis persists throughout life in the rodent subventricular zone (SVZ) and hippocampal dentate gyrus (DG). Several strategies have been employed to eliminate adult neurogenesis and thereby determine whether depleting adult-born neurons disrupts specific brain functions, but some approaches do not speci... |
2,324,057 | Chagas disease is independently associated with brain atrophy. | Chagas disease (CD) remains a major cause of cardiomyopathy and stroke in developing countries. Brain involvement in CD has been attributed to left ventricular dysfunction, resulting in chronic brain ischemia due to hypoperfusion and/or embolic infarcts. However, cognitive impairment in CD may occur independently of ca... |
2,324,058 | [Vitamin B12 deficiency and neurological disorders: a case report and literature review]. | Vitamin B12 deficiency is often associated with neurological disorders of which combined sclerosis of the spinal cord is a common manifestation.</AbstractText>We report the case of a woman who presented cerebellar ataxia and cognitive deficits associated with leukoencephalopathy on the brain MRI. These symptoms were as... |
2,324,059 | Conquering the third ventricular chamber. | Surgery within the third ventricle was a special challenge early in the conception of the discipline of neurosurgery due to a lack of diagnostic methods and difficulty in reaching and removing lesions affecting this vital region. Walter Dandy and Harvey Cushing performed pioneering approaches of the third ventricular r... |
2,324,060 | Surgical considerations in fourth ventricular ependymoma with the transcerebellomedullary fissure approach in focus. | Within the existing consensus for the best management of pediatric infratentorial ependymomas (PIE), surgery is the most important stage, where complete removal should be the perfect aim, before complementing it with chemo- or radiotherapy. That, however, remains a challenge even for the most skillful surgeons because ... |
2,324,061 | Outcome of non-transplant surgical strategy for end-stage dilated cardiomyopathy in young children.<Pagination><StartPage>1045</StartPage><EndPage>1048</EndPage><MedlinePgn>1045-8</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The shortage of heart transplantation donors is... | Purpose of the pilot study was to reveal structural and functional features of heart failure at different severity levels of ischemic cardiomyopathy (ICMP). 62 patients affected with ICMP have been involved in the study: 9 men (15%) and 51 (85%) women (average age 62,63+/-13,11). The control group was composed of 20 he... |
2,324,062 | Hypothalamic injection of oxyntomodulin suppresses circulating ghrelin-like immunoreactivity. | Ghrelin is a gastric peptide that regulates appetite and GH secretion. Circulating ghrelin levels are elevated by fasting and suppressed postprandially. However, the mechanisms regulating circulating ghrelin levels are unclear. Oxyntomodulin is an anorexic peptide hormone released from L cells in the gut. We investigat... |
2,324,063 | Insulin-like growth factor-1 and insulin-like growth factor binding proteins in cerebrospinal fluid during the development of mouse embryos. | Insulin-like growth factor-1 (IGF-1) is a potent neurotrophic factor that promotes the proliferation, migration and differentiation of glial and neuronal cells. IGF-1 can also protect neurons from undergoing apoptotic cell death. IGF-1 is produced by the choroid plexus, located in the ventricles. Knowledge of embryonic... |
2,324,064 | Herba leonurine attenuates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells. | Doxorubicin (DOX) is a highly effective antineoplastic drug. However, DOX-induced apoptosis in cardiomyocytes leads to irreversible degenerative cardiomyopathy and heart failure, which limits DOX clinical application. Leonurine is a special alkaloid for Herba leonuri, a traditional herb with cardioprotective effects. I... |
2,324,065 | Investigation of a myxoma in the right ventricular outflow tract. | We describe an atypical myxoma in the right ventricular outflow tract of a 12-year old girl. After identification using echocardiography, we assessed its precise location and attachments by magnetic resonance imaging. Subsequent to surgical removal, histology confirmed the myxomatous nature of the tumour. |
2,324,066 | Neurometabolite concentrations in gray and white matter in mild traumatic brain injury: an 1H-magnetic resonance spectroscopy study. | Single-voxel proton magnetic resonance imaging ((1)H-MRS) and proton MR spectroscopic imaging ((1)H-MRSI) were used to compare brain metabolite levels in semi-acute mild traumatic brain injury (mTBI) patients (n = 10) and matched healthy controls (n = 9). The (1)H-MRS voxel was positioned in the splenium, a region know... |
2,324,067 | Recurrent ependymoma with cartilaginous metaplasia in an adult: report of a rare case and review of literature. | Cartilaginous metaplasia in ependymomas is an uncommon phenomenon and is hypothesized to be due to metaplasia of the mesenchymal supportive elements or arising from the neoplastic glial cells. Most of the previous cases reported have occurred in children less than 10 years of age. The present report discusses an unusua... |
2,324,068 | Prenatal diagnosis by 3D ultrasound and MRI of an unusual malformation of cortical development with brain-in-brain appearance. | A 31-year-old pregnant woman was referred for isolated mild ventriculomegaly and failure to visualize the left lateral ventricle's anterior horn on second trimester sonography (US). Three-dimensional US suspected a frontal lesion deviating the midline. MRI revealed a mass compressing the ventricle. Follow-up MRI descri... |
2,324,069 | Rostro-caudal gradual loss of cellular diversity within the periventricular regions of the ventricular system. | Neurogenesis occurs constitutively within the periventricular region (PVR) of the lateral ventricles (LV) of the adult mammalian brain. The occurrence of adult neurogenesis within the PVR outside the neurogenic niche of the LV remains controversial, but neural stem cells can be isolated from PVR of the whole ventricula... |
2,324,070 | Compensatory parameters of intracranial space in giant hydrocephalus. | The main goal of the present study is to examine compensatory parameters of intracranial space in giant hydrocephalus. We also assess the early and late outcome and analyse complications in shunted cases.</AbstractText>Nine cases of giant hydrocephalus characterised by the value of Evans ratio > 0.5, ventricular ind... |
2,324,071 | Orthostatic hypotension associated with an epidermoid tumor of the IV ventricle. | We report the case of a 32-year-old man with an epidermoid tumor of the fourth ventricle. About 14 years later, he showed a tumor recurrence which was removed. After this procedure the patient complained of presyncopal and syncopal crisis while attempting to stand or walk. On examination, severe orthostatic hypotension... |
2,324,072 | Risk factors for acute symptomatic cerebral infarctions after spontaneous supratentorial intra-cerebral hemorrhage. | Cerebral infarctions are unfavorable outcomes of spontaneous intra-cerebral hemorrhage (ICH). To date, there have been no reports on risk factors that are predictive of acute symptomatic cerebral infarctions. With the aim of determining the potential risk factors that are predictive of acute symptomatic cerebral infarc... |
2,324,073 | Endurance exercise training preserves cardiac function in rats receiving doxorubicin and the HER-2 inhibitor GW2974.<Pagination><StartPage>1105</StartPage><EndPage>1113</EndPage><MedlinePgn>1105-13</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s00280-009-0967-z</ELocationID><Abstract><Abstract... | Proper brain ventricle formation during embryonic brain development is required for normal brain function. Brain ventricles are the highly conserved cavities within the brain that are filled with cerebrospinal fluid. In zebrafish, after neural tube formation, the neuroepithelium undergoes a series of constrictions and ... |
2,324,074 | Midline brain structures in teenagers with first-presentation borderline personality disorder. | Brain morphologic changes have been reported in borderline personality disorder (BPD), but it remains largely unknown whether BPD is associated with midline brain abnormalities. We used magnetic resonance imaging to investigate the length of the adhesio interthalamica (AI) and cavum septum pellucidum (CSP) as well as t... |
2,324,075 | What is your diagnosis? Intracranial mass in a dog. | A 9-year-old, spayed female Chihuahua was presented for evaluation of acute, progressive neurologic disease. On physical examination the dog was depressed and laterally recumbent. The dog had marked neutrophilia with a toxic left shift and monocytosis. Using computed tomography with contrast enhancement a large intracr... |
2,324,076 | Ultrastructure of the subventricular zone in Macaca fascicularis and evidence of a mouse-like migratory stream. | Recent publications have shown that the lateral wall of the lateral ventricles in the Macaca fascicularis brain, in particular the subventricular zone (SVZ), contains neural stem cells throughout adulthood that migrate through a migratory pathway (RMS) to the olfactory bulb (OB). To date, a detailed and systematic cyto... |
2,324,077 | Response of ependymal progenitors to spinal cord injury or enhanced physical activity in adult rat. | Ependymal cells (EC) in the spinal cord central canal (CC) are believed to be responsible for the postnatal neurogenesis following pathological or stimulatory conditions. In this study, we have analyzed the proliferation of the CC ependymal progenitors in adult rats processed to compression SCI or enhanced physical act... |
2,324,078 | Risk factors for hemorrhage during microelectrode-guided deep brain stimulation and the introduction of an improved microelectrode design. | Hemorrhage is an infrequent but potentially devastating complication of deep brain stimulation (DBS) surgery. We examined the factors associated with hemorrhage after DBS surgery and evaluated a modified microelectrode design that may improve the safety of this procedure.</AbstractText>All microelectrode-guided DBS pro... |
2,324,079 | Rosette-forming glioneuronal tumor: report of a chiasmal-optic nerve example in neurofibromatosis type 1: special pathology report. | Rosette-forming glioneuronal tumor is a rare, rather recently described tumor featuring a highly distinctive, biphasic histological pattern, including a cytologically uniform neuronal component of Homer-Wright type pseudorosettes and an accompanying astrocytic element resembling pilocytic astrocytoma. Its occurrence in... |
2,324,080 | [Behavioral change and cell proliferation in the subventricular zone in adult rats after intracerebral hemorrhage]. | To investigate the relationship between behavioral changes and cell proliferation in subventricular zone (SVZ) after intracerebral hemorrhage (ICH) in adult rats.</AbstractText>Forty male Sprague-Dawley rats were randomly assigned into a behavioral test group (n = 19) and a bromodeoxyuridine (Brdu) immunohistochemical ... |
2,324,081 | Multiscale modeling in rodent ventricular myocytes. | There is a growing body of experimental evidence suggesting that the Ca(2+) signaling in ventricular myocytes is characterized by a high gradient near the cell membrane and a more uniform Ca(2+) distribution in the cell interior [1]--[7]. An important reason for this phenomenon might be that in these cells the t-tubula... |
2,324,082 | Genetic dissection of the mouse brain using high-field magnetic resonance microscopy.<Pagination><StartPage>1067</StartPage><EndPage>1079</EndPage><MedlinePgn>1067-79</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.neuroimage.2009.01.021</ELocationID><Abstract><AbstractText>Magnetic resonance ... | Magnetic resonance (MR) imaging has demonstrated that variation in brain structure is associated with differences in behavior and disease state. However, it has rarely been practical to prospectively test causal models that link anatomical and functional differences in humans. In the present study we have combined clas... |
2,324,083 | Ventricular dilation and elevated aqueductal pulsations in a new experimental model of communicating hydrocephalus. | In communicating hydrocephalus (CH), explanations for the symptoms and clear-cut effective treatments remain elusive. Pulsatile flow through the cerebral aqueduct is often significantly elevated, but a clear link between abnormal pulsations and ventriculomegaly has yet to be identified. We sought to demonstrate measure... |
2,324,084 | Assessment of sarcoplasmic reticulum Ca2+ depletion during spontaneous Ca2+ waves in isolated permeabilized rabbit ventricular cardiomyocytes. | In this study, Ca2+ release due to spontaneous Ca2+ waves was measured both from inside the sarcoplasmic reticulum (SR) and from the cytosol of rabbit cardiomyocytes. These measurements utilized Fluo5N-AM for intra-SR Ca2+ from intact cells and Fluo5F in the cytosol of permeabilized cells. Restricted subcellular volume... |
2,324,085 | Hydrocephalus in infants less than six months of age: effectiveness of endoscopic third ventriculostomy. | Although endoscopic third ventriculostomy (ETV) is a well established procedure for the treatment of congenital and acquired hydrocephalus, there is still a controversy with regard to the higher risk of failure in younger infants compared to older children after such a procedure. The aim of this article is to define th... |
2,324,086 | Cardiocutaneous fistula in a delayed iathrogenic ventricular perforation of the heart: computed tomographic and magnetic resonance imaging findings. | Cardiac iathrogenic lesions can occur during diagnostic or therapeutic procedures. Resistance of the heart to an injury may cause a delay from the traumatic event to onset of the symptomatology or to heart rupture. We describe a rare case cardiac perforation with delayed rupture of the heart in a patient previously sub... |
2,324,087 | 3D reconstructions of the cerebral ventricles and volume quantification in children with brain malformations. | The aim of this study was to assess the ability of a semiautomated process to produce three-dimensional reconstructions of the ventricles and calculate ventricular volumes from magnetic resonance (MR) imaging data in children with structural brain abnormalities.</AbstractText>Fourteen children referred for MR imaging o... |
2,324,088 | AQP4 gene deletion in mice does not alter blood-brain barrier integrity or brain morphology. | The glial cell water channel aquaporin-4 (AQP4) plays an important role in brain edema, astrocyte migration, and neuronal excitability. Zhou et al. [Zhou J, Kong H, Hua X, Xiao M, Ding J, Hu G (2008) Altered blood-brain barrier integrity in adult aquaporin-4 knockout mice. Neuroreport 19:1-5] recently reported that AQP... |
2,324,089 | Tbx5-mediated expression of Ca(2+)/calmodulin-dependent protein kinase II is necessary for zebrafish cardiac and pectoral fin morphogenesis. | Mutations in the T-box transcription factor, TBX5, result in Holt-Oram syndrome (HOS), a human condition in which cardiac development is defective and forelimbs are stunted. Similarly, zebrafish tbx5 morphants and mutants (heartstrings; hst) lack pectoral fins and exhibit a persistently elongated heart that does not un... |
2,324,090 | Association between cardiac energy metabolism and gain of left ventricular mass in Fabry disease. | Left ventricular (LV) hypertrophy is the hallmark of cardiac involvement in Fabry disease (FD). However, its pathogenesis is not clearly understood as pathologic substrate accumulation represents only 1-2% of the total cardiac mass. Abnormal myocardial energy metabolism has been previously demonstrated in different for... |
2,324,091 | [Wallenberg syndrome and neurocysticercosis: about one case in Ouagadougou, Burkina Faso]. | Neurocysticercosis (NCC) frequently appears by seizures following parenchymatous location of encysted worms of Taenia solium. We report a case of NCC revealed by a Wallenberg's syndrome. A man of 44 years old, without any cardiovascular risk factor was admitted at the neurology department of Yalgado-Ouédraogo hosp... |
2,324,092 | Fascin1 is dispensable for mouse development but is favorable for neonatal survival. | Fascin1, an actin-bundling protein, has been demonstrated to be critical for filopodia formation in cultured cells, and thus is believed to be vital in motile activities including neurite extension and cell migration. To test whether fascin1 plays such essential roles within a whole animal, we have generated and charac... |
2,324,093 | MyD88-dependent nuclear factor-kappaB activation is involved in fibrinogen-induced hypertrophic response of cardiomyocytes. | Plasma fibrinogen has been defined as a risk factor of cardiovascular disease and may play a role in the development of cardiac hypertrophy. We have previously demonstrated that the Toll-like receptor 4 (TLR4)-mediated myeloid differentiation primary response protein 88 (MyD88)-dependent nuclear factor-kappaB (NF-kappa... |
2,324,094 | Significance of fatal head injuries associated with subependymal hemorrhage at the anterior horns of lateral ventricles. | We hypothesize the following items based on 41 autopsy cases with or without head injuries especially on subependymal injuries at the anterior horns of the lateral cerebral ventricles. The subependymal injuries at the regions (1) are not seen in fatal cases that did not have intracranial injuries, (2) have nothing to d... |
2,324,095 | Impairment of long-term depression induced by chronic brain inflammation in rats. | Although deficits in synaptic plasticity have been identified in aged or neuroinflamed animals with memory impairments, few studies have examined the cellular basis of plasticity in such animals. Here, we examined whether chronic neuroinflammation altered long-term depression (LTD) and studied the underlying mechanism ... |
2,324,096 | Maximum (prior) brain size, not atrophy, correlates with cognition in community-dwelling older people: a cross-sectional neuroimaging study. | Brain size is associated with cognitive ability in adulthood (correlation approximately .3), but few studies have investigated the relationship in normal ageing, particularly beyond age 75 years. With age both brain size and fluid-type intelligence decline, and regional atrophy is often suggested as causing decline in ... |
2,324,097 | Studies of learning and memory processes in adult rats in conditions of intracerebral administration of caspase inhibitors. | The effects of caspase inhibitors on different types of learning and memory were studied in adult rats on administration into the cerebral ventricles and application to the vermis of the cerebellum. The wide-spectrum caspase inhibitor z-VAD-fmk, given into the lateral ventricles of adult rats, facilitated the formation... |
2,324,098 | Significant roles of microtubules in mature striated muscle deduced from the correlation between tubulin and its molecular chaperone alphaB-crystallin in rat muscles. | To elucidate the significance of cytoskeletal microtubule networks in striated muscles, we analyzed correlation between the content of tubulin (building block of microtubules) and alphaB-crystallin (a molecular chaperone for tubulin) in a variety of striated muscles expressing different myosin heavy-chain (MHC) isoform... |
2,324,099 | Commotio cordis and ventricular pseudoaneurysm.<Pagination><StartPage>237</StartPage><EndPage>238</EndPage><MedlinePgn>237-8</MedlinePgn></Pagination><Abstract><AbstractText>A case of an eight-year-old boy who experienced commotio cordis with the development of myocardial infarction and a ventricular pseudoaneurysm is ... | A case of an eight-year-old boy who experienced commotio cordis with the development of myocardial infarction and a ventricular pseudoaneurysm is described. Progressive enlargement of the aneurysm resulted in distortion and compression of the overlying coronary arteries, causing myocardial ischemia.</Abstract><AuthorLi... |
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