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2,324,100 | Anatomical characterization of human fetal brain development with diffusion tensor magnetic resonance imaging. | The human brain is extraordinarily complex, and yet its origin is a simple tubular structure. Characterizing its anatomy at different stages of human fetal brain development not only aids in understanding this highly ordered process but also provides clues to detecting abnormalities caused by genetic or environmental f... |
2,324,101 | Extraventricular neurocytoma in a child: case report and review of the literature. | Neurocytomas are relatively rare central nervous system tumors first described in intraventricular sites but increasingly recognized in the brain and spinal cord parenchyma. Herewith, we report a case of a 3-year-old girl with generalized seizures. Computed tomography and magnetic resonance imaging revealed a lesion in... |
2,324,102 | Phylogenetic analysis of SRLV sequences from an arthritic sheep outbreak demonstrates the introduction of CAEV-like viruses among Spanish sheep. | Small ruminant lentiviruses (SRLVs) cause different clinical forms of disease in sheep and goats. So far in Spain, Maedi visna virus-like (MVV-like) sequences have been found in both species, and the arthritic SRLV disease has never been found in sheep until a recent outbreak. Knowing that arthritis is common in goats,... |
2,324,103 | Coexistent intraventricular abnormalities in periventricular giant arachnoid cysts. | Arachnoid cysts are congenital lesions that arise during development by splitting of the arachnoid membrane. Large cysts can be adjacent to CSF pathways causing a marked midline shift and hydrocephalus. The association between a large arachnoid cyst and hydrocephalus has been commonly described as being due to a mass e... |
2,324,104 | Electromagnetic-guided neuroendoscopy in the pediatric population. | Image-guided neuroendoscopy is being increasingly used in an attempt to reduce the morbidity associated with surgery and to make navigation easier. It has a particularly useful application in the pediatric population for the treatment of conditions such as complex hydrocephalus and arachnoid cysts. However, its use has... |
2,324,105 | [MRI morphometry of the brain ventricles in patients with attention-deficit hyperactivity disorder]. | Twenty seven right-handed subjects aged 7-30 years with the attention deficit/hyperactivity disorder (ADHD) were exposed to standard MRI examination. From them, 14 were younger than 13 years old. The volumes of lateral ventricles were measured using T1-weighted MR-images of the sagittal brain sections to within 3 mm3. ... |
2,324,106 | Cervical intradural extramedullary ependymal cyst associated with congenital dermal sinus: a case report. | Spinal intradural extramedullary ependymal cyst is a very rare entity with only few cases reported in the literature. Its association with congenital dermal sinus has not been described so far. We present a unique report of a 3-year-old male child who presented with spastic quadriparesis with a trophic ulcer in the rig... |
2,324,107 | Pilocytic astrocytoma of the optic pathway: a tumour deriving from radial glia cells with a specific gene signature. | Pilocytic astrocytomas are WHO grade I gliomas that occur predominantly in childhood. They share features of both astroglial and oligodendroglial lineages. These tumours affect preferentially the cerebellum (benign clinical course) and the optic pathway, especially the hypothalamo-chiasmatic region (poor prognosis). Un... |
2,324,108 | Traumatic brain injury: a review and high-field MRI findings in 100 unarmed combatants using a literature-based checklist approach. | This study reviewed the literature for the extent of neuroimaging findings in boxers, indicative of traumatic brain injury (TBI) as identified in magnetic resonance imaging (MRI). The study then utilized a systematic checklist approach to assess 100 unselected consecutive 1.5- and 3.0-Tesla MRI examinations of professi... |
2,324,109 | Agreement between echocardiographic techniques in assessment of the left ventricular myocardial performance index in rabbits. | OBJECTIVE-To report reference values and examine the agreement in the myocardial performance (Tei) index of the left ventricle (LVTI) as measured by tissue Doppler imaging (TDI), pulsed-wave Doppler imaging (PWD), and M-mode echocardiography in clinically normal rabbits. ANIMALS-26 clinically normal male New Zealand Wh... |
2,324,110 | [Realization of biophysical models for the cardiac electrical activity]. | Some principles for the realization of biophysical models of electrical activity of heart ventricles, presented by a double electrical layer along the surface of the electrically active myocardium and the boundary surfaces that divide model compartments with different electrophysiological properties, have been consider... |
2,324,111 | [Obesity prevention--is there any limits for primary care medicine]. | What does obesity mean? One of the people's health markers is the nutritional steady-state, the mean ponderal equilibrium. The normal weight means the longest life expectancy assuring body weight, from all points of view. The body weight increasing means adipose tissue accumulation and the onset of obesity. Obesity qua... |
2,324,112 | Post-natal investigations: management and prognosis for fetuses with CNS anomalies identified in utero excluding neurosurgical problems. | The suspicion of an abnormality of the central nervous (CNS) system raises difficult questions for the clinician and the family and will inevitably lead to considerable anxiety. These questions include what it means for the child's future, whether it can be treated and whether it will happen again in subsequent pregnan... |
2,324,113 | Evolution of neurological impairment in pediatric infratentorial ependymoma patients. | Infratentorial ependymoma is a common central nervous system tumor of childhood and in patients >1 year of age is treated with maximally feasible surgical resection and radiotherapy. Because of this tumor typically arises within the 4th ventricle and can invade the brainstem, patients are at risk for significant neu... |
2,324,114 | Radiation therapy for intracranial germ cell tumors. | Although radiation therapy (RT) is essential to the management of intracranial germ cell tumors, the ideal radiation dose and field remain controversial. For the treatment of germinoma, whole central nervous system radiation, which was once the standard RT field, is being replaced by whole ventricle (WV) field radiatio... |
2,324,115 | Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure. | Neutrophil gelatinase-associated lipocalin (NGAL or lipocalin-2) is a glycoprotein with bacteriostatic properties. Growing evidence suggests that NGAL may also be involved in cell survival, inflammation, and matrix degradation. We therefore aimed to investigate the role of NGAL in heart failure (HF).</AbstractText>Our ... |
2,324,116 | Ventricular catheter placement accuracy in non-stereotactic shunt surgery for hydrocephalus. | We aimed to compare the accuracy of different shunt catheter approaches to the lateral ventricle in adults with hydrocephalus. We conducted a retrospective review of 138 consecutive patients with hydrocephalus undergoing freehand initial shunt surgery. Of these, 79 had a post-operative brain scan and therefore the resu... |
2,324,117 | Autophagy, redox signaling, and ventricular remodeling. | Autophagy is a catabolic process through which damaged or long-lived proteins, macromolecules, or organelles are recycled by using lysosomal degradation machinery. Although the occurrence of autophagy in several cardiac diseases including ischemic or dilated cardiomyopathy, heart failure, hypertrophy, and during ischem... |
2,324,118 | Application of electromagnetic technology to neuronavigation: a revolution in image-guided neurosurgery. | The authors investigated the practicality of electromagnetic neuronavigation in routine clinical use, and determined the applications for which it is at the advantage compared with other systems.</AbstractText>A magnetic field is generated encompassing the surgical volume. Devices containing miniaturized coils can be l... |
2,324,119 | Extended endoscopic endonasal transsphenoidal approach for residual or recurrent craniopharyngiomas. | The management of recurrent or residual craniopharyngiomas remains controversial. Although possible, revision surgery is more challenging than primary surgery, and more often results in incomplete resection and an increased risk of death and complications. The extended (also called expanded) endoscopic endonasal transs... |
2,324,120 | Posthemorrhagic hydrocephalus in newborns: clinical characteristics and role of ventriculoperitoneal shunts. | The incidence of neonatal intraventricular hemorrhage (IVH) does not decrease even after using a surfactant and advanced intensive care. Posthemorrhagic hydrocephalus (PHH) is major complication after IVH. The roles of the ventricuLoperitoneal (VP) shunt and the prognostic factors of neurodevelopmental outcomes in infa... |
2,324,121 | Involvement of central alpha1-adrenoceptors on renal responses to central moxonidine and alpha-methylnoradrenaline. | Moxonidine (alpha2-adrenoceptor/imidazoline receptor agonist) injected into the lateral ventricle induces diuresis, natriuresis and renal vasodilation. Moxonidine-induced diuresis and natriuresis depend on central imidazoline receptors, while central alpha1-adrenoceptors are involved in renal vasodilation. However, the... |
2,324,122 | Angiotensin (1-7) prevent heart dysfunction and left ventricular remodeling caused by renal dysfunction in 5/6 nephrectomy mice. | The renin-angiotensin system (RAS) plays a critical role in chronic renal failure associated with heart failure. In the past few years, angiotensin (Ang) (1-7) have been reported to counteract the effects of angiotensin II (Ang II) and were even considered as a new therapeutical target in RAS. The purposes of this stud... |
2,324,123 | External ventricular drains in pediatric patients. | To determine the indications and complications of external ventricular drain (EVD) placement in pediatric patients.</AbstractText>Retrospective chart review.</AbstractText>University associated, tertiary-level Children's Hospital.</AbstractText>Sixty-six [median age, 10.1 years (interquartile range, 5.9)] patients betw... |
2,324,124 | Smaller organ mass with greater age, except for heart. | Autopsy/cadaver data indicate that many organs and tissues are smaller in the elderly compared with young adults; however, in vivo data are lacking. The aim of this study was to determine whether the mass of specific high-metabolic-rate organs is different with increasing age, using MRI. Seventy-five healthy women (41 ... |
2,324,125 | Establishment of an experimental human lung adenocarcinoma cell line SPC-A-1BM with high bone metastases potency by (99m)Tc-MDP bone scintigraphy. | Bone metastasis is one of the most common clinical phenomena of late stage lung cancer. A major impediment to understanding the pathogenesis of bone metastasis has been the lack of an appropriate animal and cell model. This study aims to establish human lung adenocarcinoma cell line with highly bone metastases potency ... |
2,324,126 | Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice. | Although nutrients, including amino acids and their metabolites such as serotonin (5-HT), are strong modulators of anxiety-related behavior, the metabolic pathway(s) responsible for this physiological modulation is not fully understood. Regarding tryptophan (Trp), the initial rate-limiting enzymes for the kynurenine pa... |
2,324,127 | Influence of intermittent hypoxia on myocardial and hepatic P-glycoprotein expression in a rodent model. | Patients with obstructive sleep apnea who receive drug therapy for cardiovascular disease may experience resistant hypertension, arrhythmias, or more severe heart failure, and many of the drugs used to treat these conditions are substrates for P-glycoprotein (P-gp) transporters. Therefore, we sought to determine if int... |
2,324,128 | Multislice multiecho T2* cardiac magnetic resonance for the detection of heterogeneous myocardial iron distribution in thalassaemia patients. | The present study investigated myocardial T2* heterogeneity in thalassaemia major (TM) patients by cardiac magnetic resonance (CMR), to determine whether is related to inhomogeneous iron overload distribution. A total of 230 TM patients consecutively referred to our laboratory were studied retrospectively. Three short-... |
2,324,129 | Transient and transgenic analysis of the zebrafish ventricular myosin heavy chain (vmhc) promoter: an inhibitory mechanism of ventricle-specific gene expression. | The zebrafish ventricular myosin heavy chain (vmhc) gene exhibits restricted expression in the ventricle. However, the molecular mechanism underlying this chamber-specific expression is unclear. Here, we exploited both transient and transgenic technologies to dissect the zebrafish vmhc promoter. We demonstrated that a ... |
2,324,130 | A longitudinal study of the maternal cardiovascular adaptation to spontaneous and assisted conception pregnancies. | To determine the sequence and extent of maternal cardiovascular adaptation in an integrated way in spontaneous and assisted conception pregnancies.</AbstractText>Cardiovascular assessments were performed pre-pregnancy, during pregnancy and 6 weeks post delivery in women with normal spontaneously conceived singleton pre... |
2,324,131 | Diagnostic value of subependymal pseudocysts and choroid plexus cysts on neonatal cerebral ultrasound: a meta-analysis. | Subependymal pseudocysts and choroid plexus cysts are seen in newborns on cerebral ultrasound. Clinicians are unsure whether these findings are related to an underlying disease which affects long-term outcome and requires medical intervention. In an attempt to establish the diagnostic value of cystic lesions on cerebra... |
2,324,132 | Colloid cyst of third ventricle presenting as pseudoeclampsia. | A 32 years old omani woman G6P4A1 at 39 weeks of pregnancy presented with complaints of headache and picture of eclampsia. Emergency caesarean section was done for maternal and foetal distress. Post caesarean section patient could not be extubated from general anaesthesia. Emergency computed tomography scan of the brai... |
2,324,133 | Cerebellar glioblastomas: pathophysiology, clinical presentation and management. | Glioblastoma multiforme usually affects the cerebral hemispheres with the peak age of onset in the sixth or seventh decade, while cerebellar glioblastoma multiforme is a rare tumour especially in younger patients. Most result from de-differentiation from low grade astrocytoma (secondary glioblastoma) or can develop de ... |
2,324,134 | Diabetic cardiomyopathy: effects of fenofibrate and metformin in an experimental model--the Zucker diabetic rat. | Diabetic cardiomyopathy (DCM) contributes to cardiac failure in diabetic patients. It is characterized by excessive lipids accumulation, with increased triacylglycerol (TAG) stores, and fibrosis in left ventricle (LV). The mechanisms responsible are incompletely known and no specific treatment is presently defined. We ... |
2,324,135 | [Influence of benzo[a]pyrene on learning and memory and content of amino acid neurotransmitters in hippocampus of rats]. | To study the effects of benzo[a]pyrene (B[a]P) on capability of learning and memory and the content of amino acid neurotransmitters in hippocampus of rats.</AbstractText>Thirty-two healthy, male SD rats were randomly divided into 4 groups according to their weights after intubated into ventricles: the solvent control g... |
2,324,136 | Morphometric study on dimensions of various parts of pons and comparison of data in accordance with age and sex of healthy people by MRI. | The emergence of magnetic Resonance Imaging (MRI) technique has made it possible to answer many questions in the field of anatomy more precisely while observing different anatomic parts of living persons at different ages. This study was conducted to determine the dimensions of different parts of pons and also comparin... |
2,324,137 | A rat glioblastoma model with diffuse leptomeningeal gliomatosis induced by intracarotid injection of C6 glioma cells. | A reproducible brain tumor model using experimental animals is required to study biological behavior and develop more potent antineoplastic drugs and effective therapeutic modalities. In this work, we attempted to establish diffuse leptomeningeal gliomatosis in the rat by intracarotid injection of C6 glioma cells.</Abs... |
2,324,138 | Cancer and depression: a prospective study. | Cancer diagnosis and treatment often produce psychologic stresses resulting from the actual symptoms of the disease, as well as from perceptions of the disease and its stigma. Depression is seen in many cancer patients. Depression occurs in approximately 25% of palliative care patients. It is widely recognised by clini... |
2,324,139 | Information for better or for worse: interviews with parents when their foetus was found to have choroid plexus cysts at a routine second trimester ultrasound. | The aim of the study was to gain a theoretical understanding of parents' experiences and handling of the situation, when their foetus was diagnosed as having choroid plexus cysts, at a routine second trimester ultrasound examination. Nine couples and one mother were interviewed using one open question. Analysis method ... |
2,324,140 | Endogenous sulfur dioxide aggravates myocardial injury in isolated rat heart with ischemia and reperfusion. | Ischemia-reperfusion (I/R) injury is an important clinical problem. This article investigated the role of sulfur dioxide (SO2) in the regulation of cardiac function and in the pathogenesis of cardiac I/R injury in isolated rat heart.</AbstractText>Rat hearts isolated on a Langendorff apparatus were divided into control... |
2,324,141 | Treatment of posthemorrhagic hydrocephalus in premature infants with subcutaneous reservoir drainage. | To investigate the effectiveness of subcutaneous reservoir drainage as a treatment for the different types of posthemorrhagic hydrocephalus in premature infants.</AbstractText>11 premature infants with posthemorrhagic hydrocephalus underwent subcutaneous reservoir embedment surgery, and cerebrospinal fluid (CSF) was dr... |
2,324,142 | Effect of chronic apocynin treatment on nitric oxide and reactive oxygen species production in borderline and spontaneous hypertension. | The purpose of this study was to investigate the effect of NAD(P)H oxidase inhibitor - apocynin (4-hydroxy-3-methoxyacetophenone) on the increase of systolic blood pressure (SBP) in borderline (BHR) and spontaneously hypertensive rats (SHR). Young 6-week-old male BHR (offspring of SHR dams and Wistar Kyoto sires) and S... |
2,324,143 | Sepiapterin decreases acute rejection and apoptosis in cardiac transplants independently of changes in nitric oxide and inducible nitric-oxide synthase dimerization. | Tetrahydrobiopterin (BH(4)), a cofactor of inducible nitric-oxide synthase (iNOS), is an important post-translational regulator of NO bioactivity. We examined whether treatment of cardiac allograft recipients with sepiapterin [S-(-)-2-amino-7,8-dihydro-6-(2-hydroxy-1-oxopropyl)-4-(1H)-pteridinone], a precursor of BH(4)... |
2,324,144 | Cystic papillary meningioma with subarachnoid dissemination: a case report and review of the literature. | Meningiomas usually present as benign tumors corresponding to WHO grade I. The development of the papillary variant of meningiomas with cyst formation in the central nervous system is extremely rare. We report a case of cystic papillary meningioma in a young female occurring in the lateral ventricle with invasion of br... |
2,324,145 | [Neuroendoscopic management of a colloid cyst at the third ventricle using the high-definition flexible neuroendoscopic system: report of two cases]. | Colloid cysts are benign intracranial lesions located at the anterior roof of the third ventricle, which can result in the obstruction of the foramen of Monro and subsequent hydrocephalus or sudden death. Colloid cysts have been treated by microsurgical resection or by stereotactic aspiration. More recently, the use of... |
2,324,146 | Influence of myocardial fibrosis and blood oxygenation on heart T2* values in thalassemia patients. | To determine whether T2* measurements quantifying myocardial iron overload in thalassemia patients are influenced by myocardial fibrosis and blood oxygenation.</AbstractText>Multislice multiecho T2* was performed in 94 thalassemia patients in order to quantify myocardial iron overload. The left ventricle was automatica... |
2,324,147 | Immunohistochemical study of postnatal neurogenesis after whole-body exposure to electromagnetic fields: evaluation of age- and dose-related changes in rats. | It is well established that strong electromagnetic fields (EMFs) can give rise to acute health effects, such as burns, which can be effectively prevented by respecting exposure guidelines and regulations. Current concerns are instead directed toward the possibility that long-term exposure to weak EMF might have detrime... |
2,324,148 | C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. | Interleukin 17-producing T helper cells (T(H)-17 cells) are important in experimental autoimmune encephalomyelitis, but their route of entry into the central nervous system (CNS) and their contribution relative to that of other effector T cells remain to be determined. Here we found that mice lacking CCR6, a chemokine ... |
2,324,149 | Coupling poroelasticity and CFD for cerebrospinal fluid hydrodynamics. | This research uses a novel coupling of poroelastic theory and computational fluid dynamics to investigate acute hydrocephalus resulting from stenosis of the cerebral aqueduct. By coupling poroelastic theory with a multidimensional simulation of the cerebral aqueduct we are able to investigate, for the first time, the i... |
2,324,150 | [Normal values for cerebrospinal fluid flow dynamics in the aqueduct of Sylvius through optimized analysis of phase-contrast MR images]. | To establish normal values for the different parameters that characterize the cerebrospinal fluid (CSF) flow dynamics in the aqueduct of Sylvius (velocity, flow, volume per cycle, and CSF production) obtained from phase-contrast MR images using a reliable and reproducible post-processing method. The optimized semiautom... |
2,324,151 | Avoiding the ventricle: a simple step to improve accuracy of anatomical targeting during deep brain stimulation. | The authors examined the accuracy of anatomical targeting during electrode implantation for deep brain stimulation in functional neurosurgical procedures. Special attention was focused on the impact that ventricular involvement of the electrode trajectory had on targeting accuracy.</AbstractText>The targeting error dur... |
2,324,152 | Trigonal cavernous angioma: a short illustrated review. | Intraventricular cavernomas are rare. Even more rare are those presenting in the trigone of the lateral ventricles.</AbstractText>We performed a search of the literature of the last 30 years and identified all cases of intraventricular cavernous angiomas. Trigonal cavernomas were separately identified and analysed. Our... |
2,324,153 | Relationship between ventricular morphology and aqueductal cerebrospinal fluid flow in healthy and communicating hydrocephalus. | Differences in the magnitude of cerebrospinal fluid (CSF) volumetric flow through the cerebral aqueduct between healthy and hydrocephalic patients have been previously reported. However it is not clear whether this is directly related to the pathophysiology or secondary to altered ventricular morphology and hydrodynami... |
2,324,154 | Hypophyseal triplication: case report and embryologic considerations. | Hypophyseal triplication is malformation that has not been described previously. We present a child with midline abnormalities who underwent epignathus excision at birth. Brain MR imaging revealed 2 paired lateral pituitary glands and an oval midline gland, each with an independent stalk, connected to a thickened third... |
2,324,155 | Postnatal development of an estradiol-kisspeptin positive feedback mechanism implicated in puberty onset. | The regulation of GnRH neurons by kisspeptin is critical for normal puberty onset in mammals. In the rodent the kisspeptin neurons innervating GnRH neurons are thought to reside in the rostral periventricular area of the third ventricle (RP3V). Using kisspeptin immunocytochemistry we show that kisspeptin peptide expres... |
2,324,156 | [Fetal cerebral magnetic resonance imaging (MRI). Indications, normal and pathological patterns]. | Fetal MRI is a specific imaging modality, always performed after a reference ultrasound examination. The decision to perform an MRI-scan must take into account the anxiety constantly generated by the need for this unusual examination during pregnancy. To date, no side-effect associated with 1.5 tesla magnets has been d... |
2,324,157 | Lithium restores neurogenesis in the subventricular zone of the Ts65Dn mouse, a model for Down syndrome. | Down syndrome (DS), a high-incidence genetic pathology, involves brain hypoplasia and mental retardation. Emerging evidence suggests that reduced neurogenesis may be a major determinant of brain underdevelopment in DS. To establish whether it is possible to improve neurogenesis in DS, Ts65Dn mice--the most widely used ... |
2,324,158 | Effect of sublethal exposure of Cartap on hypothalamo-neurosecretory system of the freshwater spotted murrel, Channa punctatus (Bloch). | In order to record the effect of carbamate pesticide on hypothalamus of Channa punctatus, fish were exposed to sublethal concentration (0.18 mg l(-1), 30% LC50 for 96 hr) of Cartap for 24, 48, 72 and 96 hr under static bioassay condition. Hypothalamo-neurosecretory complex of the murrel consisted mainly of nucleus preo... |
2,324,159 | Exercise training inducibility of MnSOD protein expression and activity is retained while reducing prooxidant signaling in the heart of senescent rats. | While the stress response to heat and exercise is limited in the heart with progressive aging, recent data indicate that acute or short-term exercise upregulates the Mn isoform of superoxide dismutase (MnSOD), which may provide protection against ischemia-reperfusion injury and cell death by reducing oxidative stress. ... |
2,324,160 | Immediate postoperative death due to hypothalamic injury following surgery for craniopharyngioma. | Autonomic disturbances due to hypothalamic injury that result in postoperative death are rare complications following surgery for craniopharyngioma. We discuss the case of a child who died due to hypothalamic injury following radical excision of a multi-compartmental craniopharyngioma. Mechanisms and clinical manifesta... |
2,324,161 | A rare case of left ventricular intramural hemangioma diagnosed using 1.5-T cardiac MRI with histopathological correlation and successfully treated by surgery. | Hemangiomas are vascular tumors composed of blood vessels, frequently localized in the skin and subcutaneous muscles; their localization in the heart is exceptional. The most common localizations are the lateral walls of the left ventricle, the anterior wall, and the septum. Mostly, these tumors grow intracavitarily, r... |
2,324,162 | Endoscopic management of brainstem injury due to ventriculoperitoneal shunt placement. | We report a patient who suffered from brainstem injury following ventriculoperitoneal (VP) shunt placement in the fourth ventricle.</AbstractText>A 20-year-old man with complex hydrocephalus and trapped fourth ventricle underwent a suboccipital placement of a VP shunt. Postprocedure patient developed double vision. Mag... |
2,324,163 | Fatal cerebral hemorrhage in a patient with CD19-positive IgM-producing aggressive plasma cell myeloma, hyperviscosity syndrome and cryoglobulinemia. | IgM plasma cell myeloma (PCM) is a rare entity, and CD19 positivity is found in only 1-4% of PCM. Here we report a unique case of IgM PCM, in which the plasma cells are positive for CD19. Clinically, the patient presented with hyperviscosity syndrome, mimicking the clinical manifestation of Waldenstrom's macroglobuline... |
2,324,164 | Localization of reversion-induced LIM protein (RIL) in the rat central nervous system. | Reversion-induced LIM protein (RIL) is a member of the ALP (actinin-associated LIM protein) subfamily of the PDZ/LIM protein family. RIL serves as an adaptor protein and seems to regulate cytoskeletons. Immunoblotting suggested that RIL is concentrated in the astrocytes in the central nervous system. We then examined t... |
2,324,165 | Developmental abnormalities of the posterior pituitary gland. | While the molecular mechanisms of anterior pituitary development are now better understood than in the past, both in animals and in humans, little is known about the mechanisms regulating posterior pituitary development. The posterior pituitary gland is formed by the evagination of neural tissue from the floor of the t... |
2,324,166 | Relation between abnormalities in circadian blood pressure rhythm and target organ damage in normotensives. | To determine the individual effect of abnormalities in blood pressure (BP) circadian rhythm (non-dipping status (NDS), increased morning BP (MBP) or increased MBP surge (MBPS)) on target organ damage (TOD) and which of these is more closely related to TOD in normotensives.</AbstractText>The 24-h ambulatory BP monitorin... |
2,324,167 | Prospective surveillance of drain associated meningitis/ventriculitis in a neurosurgery and neurological intensive care unit. | There are currently no data available on drain associated infection occurrence related to the number of drainage days (DD), and thus drain associated infection rates. Therefore, a prospective surveillance study was conducted to determine drain associated infection rates and DD of hospital acquired external ventricular ... |
2,324,168 | Expression of TRPM8 in the distal cerebrospinal fluid-contacting neurons in the brain mesencephalon of rats. | It has been shown that distal cerebrospinal fluid-contacting neurons (dCSF-CNs) exist near the ventral midline of the midbrain aqueduct and also in the grey matter of the inferior third ventricle and the fourth ventricle floor in the superior segment of the pons. The dCSF-CNs communicate between the cerebrospinal fluid... |
2,324,169 | [Expression of p38MAPK in the olfactory bulb of rats with Alzheimer's disease]. | To identify the changes of expression of p38MAPK in the olfactory bulb (OB) of rats with Alzheimer's Disease (AD) and to explore the functional mechanism of p38MAPK in the pathological changes of AD.</AbstractText>AD animal model was established by injecting amyloid-beta peptide 25-35 into the lateral cerebral ventricl... |
2,324,170 | [Septal delineation using a 20 % diluted contrast chaser bolus in coronary CT angiography: a comparison of 64-slice and dual source CT]. | Due to the technical advance of multislice cardiac CT and the recently introduced dual source CT, the acquisition times for cardiac CT exams are < 10 sec. At the same time the assessment of left ventricular function is possible. However, in many patients a complete right ventricular outwash is noted, leading to insu... |
2,324,171 | The FGF-2/FGFRs neurotrophic system promotes neurogenesis in the adult brain. | Neurogenesis occurs in two regions of the adult brain, namely, the subventricular zone (SVZ) throughout the wall of the lateral ventricle and the subgranular zone (SGZ) of the dentate gyrus (DG) in hippocampal formation. Adult neurogenesis requires several neurotrophic factors to sustain and regulate the proliferation ... |
2,324,172 | Speckle tracking in the evaluation of left ventricular dyssynchrony. | A number of echocardiographic techniques have been introduced to determine left ventricular dyssynchrony (LVD) and to improve selection of patients for CRT. During the last years tissue Doppler imaging (TDI) has been used as the most preferred technique to quantify LVD, but results with nonresponder rates below 30% hav... |
2,324,173 | A 15 year old boy with a posterior fossa tumor. | A 15 year old male presented with hydrocephalus from a tectal mass obstructing the cerebral aqueduct and upper fourth ventricle. The solid-cystic partly enhancing mass proved to be a pigmented pleomorphic xanthoastrocytoma, the third such example reported. The lesion revealed typical features of a PXA with the unusual ... |
2,324,174 | Posterior fossa tumor in a 2 year-old girl. | We report a case of a 2 year-old girl who presented with three weeks' history of deterioration of walking, then became unable to walk and later she developed projectile vomiting. Neurological examination revealed bilateral papilledema, nystagmus, and truncal ataxia with intention tremor. Radiological studies showed an ... |
2,324,175 | A 32-year-old man with a fourth ventricular mass. | Lipoastrocytomas are rare and only four cases have been reported previously. Our case is in the fourth ventricle of a 32 year-old man.Many areas showed tumor cells with a signet-ring appearance and focally formed perivascular arrangements. Eosinophilic granular bodies were frequent. There was strong positive immunoreac... |
2,324,176 | Intraventricular ganglioglioma: a short illustrated review. | The following review of the literature describes the ganglioglioma, an uncommon mixed glioneuronal neoplasm, most often of low-grade histology, with a small, albeit well-documented, malignant potential. These tumors exhibit a strong epileptogenic propensity and most often present as new onset seizures or are discovered... |
2,324,177 | Effect of insulin and glucose infusion on myocardial infarction size in uraemic rats. | The post myocardial infarction (MI) mortality rate is high in renal patients. One possible explanation is the reduced ischemia tolerance caused by uraemia. Previous investigations showed larger MI size in uraemic rats when compared with sham-operated controls. To explore a possible link between uraemic insulin resistan... |
2,324,178 | miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. | The subventricular zone (SVZ) is the largest neurogenic niche in the adult mammalian brain. We found that the brain-enriched microRNA miR-124 is an important regulator of the temporal progression of adult neurogenesis in mice. Knockdown of endogenous miR-124 maintained purified SVZ stem cells as dividing precursors, wh... |
2,324,179 | Characterization of brain development in the ferret via MRI. | Animal models with complex cortical development are useful for improving our understanding of the wide spectrum of neurodevelopmental challenges facing human preterm infants. MRI techniques can define both cerebral injury and alterations in cerebral development with translation between animal models and the human infan... |
2,324,180 | Interleukin-10 and interleukin-10 receptor-I are upregulated in glial cells after an excitotoxic injury to the postnatal rat brain. | Inflammation is an important determinant of the severity and outcome of central nervous system injury. The endogenous anti-inflammatory cytokine interleukin-10 (IL-10) is upregulated in the injured adult central nervous system where it controls and terminates inflammatory processes. The developing brain, however, displ... |
2,324,181 | Prenatal cocaine exposure abolished ischemic preconditioning-induced protection in adult male rat hearts: role of PKCepsilon. | Prenatal cocaine exposure in rats resulted in decreased PKCepsilon protein expression in the heart of adult male but not female offspring. The present study determined its functional consequence of inhibiting cardioprotection mediated by ischemic preconditioning. Pregnant Sprague-Dawley rats were administered intraperi... |
2,324,182 | Effects of deferoxamine on intracerebral hemorrhage-induced brain injury in aged rats. | Deferoxamine (DFX) reduces brain edema, neuronal death, and neurological deficits after intracerebral hemorrhage (ICH) in young rats. In the present study, we investigated whether DFX is effective on brain injury after ICH in aged rats and examined dose dependency.</AbstractText>Male Fischer 344 rats (18 months old) ha... |
2,324,183 | Bone marrow mesenchymal stem cells upregulate transient outward potassium currents in postnatal rat ventricular myocytes. | Bone marrow mesenchymal stem cell (BMSC) transplantation has been shown to effectively improve cardiac function in experimental animals and patients with myocardial infarction and heart hypertrophy. BMSCs exert potent effects on cardiomyocytes through the inhibition of cardiac apoptosis, the attenuation of cardiac infl... |
2,324,184 | Neuropeptide Y stimulates proliferation, migration and differentiation of neural precursors from the subventricular zone in adult mice. | The neuropeptide Y (NPY) is widely expressed in the central nervous system and has been shown to stimulate neurogenesis in the hippocampus and the olfactory epithelium. Here, we demonstrate that intracerebroventricular injection of NPY stimulates proliferation of neural precursors in the mice subventricular zone (SVZ),... |
2,324,185 | Rapid intracerebroventricular delivery of Cu-DOTA-etanercept after peripheral administration demonstrated by PET imaging. | The cytokines interleukin-1 and tumor necrosis factor (TNF), and the cytokine blocker interleukin-1 receptor antagonist, all have been demonstrated to enter the cerebrospinal fluid (CSF) following peripheral administration. Recent reports of rapid clinical improvement in patients with Alzheimer's disease and related fo... |
2,324,186 | The role of endoscopic third ventriculostomy in adult patients with hydrocephalus. | Endoscopic third ventriculostomy (ETV) is the treatment of choice for hydrocephalus, but the outcome is dependent on the cause of this disorder, and the procedure remains principally the preserve of pediatric neurosurgeons. The role of ETV in adult patients with hydrocephalus was therefore investigated.</AbstractText>O... |
2,324,187 | Expression of EAAT-1 distinguishes choroid plexus tumors from normal and reactive choroid plexus epithelium. | Microscopic distinction of normal choroid plexus (CP) from choroid plexus tumors (CPT) may be difficult, especially in small samples of well-differentiated CP papillomas. So far, there are no established markers that reliably distinguish normal and neoplastic CP epithelium. Recently, a correlation between expression/fu... |
2,324,188 | Characterization of arterial wave reflection in healthy bonnet macaques: feasibility of applanation tonometry. | Nonhuman primates are commonly used in cardiovascular research. Increased arterial stiffness is a marker of subclinical atherosclerosis and higher CV risk. We determined the augmentation index (AI) using applanation tonometry in 61 healthy monkeys (59% female, age 1-25 years). Technically adequate studies were obtained... |
2,324,189 | Percutaneous aspiration of spinal terminal ventricle cysts using real-time magnetic resonance imaging and navigation. | Clinical case series.</AbstractText>To present a new innovative treatment option for cysts of the terminal ventricle.</AbstractText>Invasive surgery including laminectomy and cyst fenestration has been the sole reported method of treatment for this rare pathology.</AbstractText>Four cases of symptomatic cyst of the ter... |
2,324,190 | Primary medulla oblongata germinoma--an unusual posterior fossa tumors in young adults. | We encountered 2 patients with germinoma arising from the medulla oblongata in whom preoperative radiological diagnosis was difficult. A 30-year-old woman presented due to aspiration pneumonia caused by bilateral lower cranial nerve palsies, and a 24-year-old man presented with headache caused by obstructive hydrocepha... |
2,324,191 | Ventricular K+ currents are reduced in mice with elevated levels of serum TNFalpha. | In the present study mice were treated with tumor necrosis factor alpha (TNFalpha) for 6 weeks to determine if chronic TNFalpha treatment could produce serum levels of TNFalpha similar to what has been observed in disease states (heart failure, HIV) and to determine if these levels of TNFalpha alter ventricular K(+) cu... |
2,324,192 | Neurotransmitter responsiveness during early maturation of neural progenitor cells. | Neurotransmitters are potential regulators of proliferation and differentiation of neural progenitor cells (NPC). To gain insight into the dynamics of neurotransmitter responsiveness, neurospheres were prepared from the lateral ventricles of postnatal day 6/7 mice. Individual NPCs migrating out from spheres were simult... |
2,324,193 | Regional shape abnormalities in mild cognitive impairment and Alzheimer's disease. | Magnetic resonance (MR) based shape analysis provides an opportunity to detect regional specificity of volumetric changes that may distinguish mild cognitive impairment (MCI) and Alzheimer's disease (AD) from healthy elderly controls (CON), and predict future conversion to AD. We assessed the surface deformation of sev... |
2,324,194 | Monozygotic twins discordant for Dandy-Walker malformation. | Dandy-Walker malformation is a congenital brain abnormality involving the fourth ventricle and cerebellum. We report on a case of twins discordant for this disorder diagnosed in the second trimester of gestation. The twin pregnancy was revealed to be monozygotic using DNA investigation. To our knowledge, this is the fi... |
2,324,195 | Transtubular microendoscopic approach for resection of a choroidal arteriovenous malformation. | The authors describe the novel use of a table-mounted tubular retractor system (MetRx) originally designed for minimally invasive spine surgery, in the resection of an intraventricular arteriovenous malformation (AVM) in a 12-year-old child. The tubular retractor system may have several advantages over traditional Gree... |
2,324,196 | Endoscopic options in children: experience with 134 procedures. | There are frequent applications for endoscopy in neurosurgery. However, endoscopic surgery in children has peculiar characteristics and is associated with different rates of success. In this study, the authors report on their experience with 134 consecutive endoscopy procedures performed in 126 patients<18 years of ... |
2,324,197 | In vivo proton magnetic resonance spectroscopy of intraventricular tumours of the brain. | The aim of this study was to assess the usefulness of proton MR spectroscopy in the diagnosis of intraventricular tumours. Fifty-two intraventricular tumours pertaining to 16 different tumour types were derived from our database. All cases had single-voxel proton MR spectroscopy performed at TE at both 30 and 136 ms at... |
2,324,198 | Effects of failed commissuration on the septum pellucidum and fornix: implications for fetal imaging. | In the previous article, we considered the normal appearances of the midline stuctures of the brain as they appear on high-resolution magnetic resonance imaging. In this article, we discuss the effects of failed commissuration on the midline structures. We highlight some of the misconceptions of this process that may l... |
2,324,199 | Prognostic relevance of metabolic approach in patients with heart failure. | Progressions in acute cardiac care have improved survival after acute myocardial infarction, but in contraposition with this, there has been an increase in mortality because of heart failure. For this reason congestive heart failure is an increasingly widespread, costly and deadly disease, frequently named as epidemic ... |
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