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25,800 | [Sudden Cardiac Death in Patients With Ischemic Heart Disease: From Mechanisms
to Clinical Practice]. | Ischemic heart disease (IHD) and acute coronary syndrome are the main cause of
sudden cardiac death (SCD). Incidence of SCD in patients after myocardial
infarction (MI) is 4-6-fold higher than in general population. The review
focuses on electrophysiological changes during acute myocardial ischemia and
mechanisms o... |
25,801 | [Takotsubo Cardiomyopathy as a Consequence of Myocardial Infarction. It is
Possible?]. | Takotsubo cardiomyopathy (TCM) is a well-known complication of many conditions
associated with emotional or physical stress. Abnormal catecholamine release has
been hypothesized to be the main cause of TCM. Myocardial infarction (MI) is
associated with release of large amounts of catecholamines. We present here two ... |
25,802 | [Structural and Functional Properties of the Left Atrium in Healthy Volunteers
and Patients With Atrial Fibrillation: Data of Magnetic Resonance Imaging]. | BACKGROUND: in the recent years, there has been an increasing number of
publications postulating that data on left atrial (LA) structure obtained by
late gadolinium enhancement magnetic resonance imaging (LGE MRI) can improve the
management of patients with atrial fibrillation (AF). At the same time, similar
data r... |
25,803 | [Effect of Type 2 Diabetes Mellitus on Five‑Year Survival of Patients
Hospitalized Because of Acute Decompensated Heart Failure]. | OBJECTIVE: To assess the impact of type 2 diabetes mellitus (T2DM) on prognosis
of patients hospitalized because of acute decompensated heart failure (ADHF).
MATERIALS AND METHODS: We analyzed data of the hospital register of ADHF which
comprised information on 735 patients (254 [35%] with T2DM) consecutively
admitt... |
25,804 | [Head to Head Comparison of Suppression of Tumorogenicity 2 and Copeptin
Significance for Prognosis of Patients After Acute Heart Failure
Decompensation]. | PURPOSE: To assess the suppression of tumorogenicity 2 (ST2) and copeptin
significance for risk stratification of patient (pts) with acute decompensated
heart failure (ADHF) during long-term follow-up compared with traditional risk
factors.
METHODS: We included in a prospective study 159 pts with ADHF. Blood samples... |
25,805 | [Effects of High-Dose Statin Therapy on Cognitive Functions and Quality of Life
in Very High Cardiovascular Risk Patients]. | AIM: To investigate the effects of intensive lipid-lowering therapy on cognitive
functions and quality of life in patients (pts) with very high cardiovascular
risk.
MATERIAL AND METHODS: In 93 pts (58 men, 63.2±9.5 years old with history of
clinically evident cardiovascular disease and fasting low-density lipoprotei... |
25,806 | [Randomized Comparison of Two Approaches to Initial Warfarin Dosing: Time in
Therapeutic Range of International Normalized Ratio During Hospitalization]. | AIM: To perform a randomized, open-label comparison of average time in
therapeutic range (TTR) of international normalized ratio (INR) using two
approaches to initial warfarin dosing during hospitalization: the standard
method and the one using individual patient characteristics (clinical algorithm
- the studied ap... |
25,807 | [Current Echocardiographic Techniques for Evaluation of the Right Ventricle]. | The review is dedicated to the new echocardiographic techniques in the
assessment of right ventricular (RV) function, such as two-dimensional speckle
tracking and determining the RV volume by a three-dimensional model. Subclinical
changes in RV function are of great importance for the diagnosis and assessment
of pr... |
25,808 | [Lizinopril in the Treatment of Arterial Hypertension]. | Despite availability of a wide selection of antihypertensive drugs, only a small
portion of patients with arterial hypertension are treated effectively.
Angiotensin converting enzyme inhibitors (ACEI) are considered drugs of first
choice for starting therapy of uncomplicated arterial hypertension. Among large
numbe... |
25,809 | [Impaired kidney function in patients with atrial fibrillation: practical
aspects]. | The article focuses on practical aspects of managing patients with a frequently
observed combination of atrial fibrillation (AF) and chronic kidney disease
(CKD). Based on the authors» own data taken as an example, incidence of
different CKD stages in CKD patients was compared with international reports.
EchoCG cha... |
25,810 | [Major predictors of stent thrombosis in patients with acute coronary syndrome
following transcutaneous coronary intervention who received different double
antiplatelet therapy]. | The review analyzes the reports addressing from different standpoints the issue
of stent thrombosis and its major predictors in patients with acute coronary
syndrome following transcutaneous coronary interventions. The review focuses on
comparative efficacy and safety of ticagrelor and clopidogrel and the effect of ... |
25,811 | [Hypertrophic cardiomyopathy and ischemic heart disease: the problem of
pathology combination]. | Hypertrophic cardiomyopathy (HCM) is a disease with left ventricular hypertrophy
caused by mutations in the genes of myocardial contractile proteins, whose
frequency is about 0.5 %. Due to the high incidence of anginal pain and marked
changes in ECG with HCM, the problem of diagnosing the combination of HCM and
cor... |
25,812 | [Selection of antiplatelet therapy for patients with stable angina]. | Acetylsalicylic acid (ASA) has a 120‑years long history. First ASA was used as
an antipyretic and anesthetic medicine, nowadays it is widely prescribed to
patients with coronary arteries disease as antithrombotic cure for prevention of
major adverse clinical events (MACE). Though there are a lot of trials about
usa... |
25,813 | [Practical aspects of anticoagulant therapy in patients with atrial fibrillation
and arterial hypertension]. | Atrial fibrillation (AF) represents the most frequent sustained cardiac
arrhythmia, the prevalence of AF is 1-2 % in the general population and up to 6
% for population over 80 years. Arterial hypertension (AH) is the commonest
background comorbidity in patients with AF. Patients with AF have 3-6‑fold
increased ris... |
25,814 | [Structural and functional changes of blood vessels in women in early
postmenopause, the possibility of correction of the revealed violations]. | AIM: To evaluate severity and pattern of structural and functional changes of
vascular wall in early postmenopausal women receiving chronic treatment with a
low-dose combination of 17β-estradiol (E2) 1 mg and drospirenone 2 mg (DRSP).
Evaluation of structural and functional arterial remodeling might be important
fo... |
25,815 | [Hepcidin and its relationship with inflammation in old and older patients with
anemia of chronic disease associated with CHF]. | BACKGROUND: Reported levels of hepcidin, the major regulator of systemic iron
homeostasis in CHF patients, are controversial. Relationship of hepcidin with
inflammation markers, which are typically increased in CHF, is understudied;
this issue is practically unstudied in old and older CHF patients.
AIM: To study the... |
25,816 | [Transthyretin amyloidosis in a cohort of old and very old patients with chronic
heart failure]. | BACKGROUND: Life-time diagnostics of wild type transthyretin amyloidosis
(ATTR(wt)-amyloidosis) is virtually absent, even though ATTR(wt)-amyloidosis is
an underestimated cause for morbidity and mortality, particularly in the older
age group.
AIM: To study incidence, demographic characteristics, and morpho-functiona... |
25,817 | [Effect of right ventricular myocardial contractility on the response to cardiac
resynchronization therapy]. | AIM: To determine the effect of right ventricular myocardial contractility on
the response to cardiac resynchronization therapy (CRT).
MATERIALS AND METHODS: The study included 80 patients (49 men, mean age 54±10.5)
diagnosed with dilated cardiomyopathy, complete left bundle branch block, and
the QRS complex width 1... |
25,818 | [Time-related changes in prevalence of chronic heart failure and diabetes
mellitus in Nizhny Novgorod Region between 2000 and 2017]. | AIM: To determine time-related changes in prevalence, morbidity, and all-cause
mortality of patients with CHF depending on the presence of DM in a
representative sample of Nizhny Novgorod Region.
MATERIALS AND METHODS: In 1998, a representative sample of Nizhny Novgorod
Region was created, which included 1922 respon... |
25,819 | [Mineral and bone disorders in chronic heart failure]. | In many patients, chronic heart failure (CHF) is associated with chronic kidney
disease (CKD). Virtually all patients with terminal CKD and many patients with
early CKD display various disorders of mineral and bone metabolism (MBM) related
with all-cause mortality and high risk of cardiovascular complications. This ... |
25,820 | [High On-Treatment Platelet Reactivity Determinants on Dual Antiplatelet Therapy
in Patients With Ischemic Heart Disease Before Elective Percutaneous Coronary
Intervention]. | OBJECTIVE: to determine impact of different laboratory and genetic factors on
high on-treatment platelet reactivity (HOPR) during dual antiplatelet therapy
(DAPT).
METHODS: We included in this study 94 patients with stable ischemic heart
disease (mean age 59±9.67 years). All patients underwent elective PCI with
imp... |
25,821 | [Radiofrequency Pulmonary Artery Ablation for Treatment of Residual Pulmonary
Hypertension After Pulmonary Endarterectomy]. | OBJECTIVE: to assess the safety and efficiency of radiofrequency pulmonary
artery ablation for treatment of residual pulmonary hypertension after pulmonary
endarterectomy.
MATERIAL AND METHODS: Radiofrequency pulmonary artery denervation (PADN) was
performed in 16 patients (10 men, mean age 39 years [26; 51]). Indic... |
25,822 | [Deficit of Magnesium and States of Hypercoagulation: Intellectual Analysis of
Data Obtained From a Sample of Patients Aged 18-50 years From Medical and
Preventive Facilities in Russia]. | The states characterized by pronounced hypercoagulable components (deep vein
thrombosis, cardio- and cerebro-vascular pathologies) are caused by multiple
pathophysiological factors, including insufficient supply of magnesium (Mg) and
other micronutrients.
AIM: to present results of analysis of the Institute of Micro... |
25,823 | [Contractile Function of Isolated Hearts With Preserved and Reduced Ejection
Fraction In Vivo]. | The aim of the study was comparison of contractile function of isolated hearts
of rats with doxorubicin-induced myocardial injury which were tentatively
divided according to the level of ejection fraction determined by
echocardiography in vivo. After 4 weeks of doxorubicin administration (2 mg/kg
subcutaneously onc... |
25,824 | [Relationship of Remodeling of Carotid Arteries and Left Ventricular Geometry in
Patients With Chronic Glomerulonephritis]. | PURPOSE: to study clinical-functional features of remodeling of carotid arteries
and its relation to restructuring of the left ventricle (LV) in patients with
chronic glomerulonephritis at pre-dialysis stage.
MATERIALS AND METHODS: We examined 269 patients (189 men, 80 women) with chronic
glomerulonephritis (CGN) ag... |
25,825 | [Polymorphisms of the SCN10A Gene in Patients With Sick Sinus Syndrome]. | PURPOSE: To study association of rs6795970 polymorphism of SCN10A gene with
development of idiopathic sick sinus syndrome (ISSS).
MATERIALS AND METHODS: We examined 109 patients with ISSS, 59 their healthy
1‑st-, 2‑nd-, and 3‑rd-degree relatives, and 630 controls. Patients with ISSS
were divided into subgroups accor... |
25,826 | [Chronic Kidney Disease as Basis of High Thrombotic and Bleeding Risk in
Patients With Atrial Fibrillation: Place of Oral Anticoagulants]. | Chronic kidney disease (CKD) aggravates course of practically all diseases by
worsening outcomes and hindering adequate treatment. Specificities of renal
excretion of various drugs, changes of parameters of their pharmacokinetics and
pharmacodynamics, nephrotoxic effects of drugs, tactics of drug therapy in
conditi... |
25,827 | [Nonvalvular Atrial Fibrillation and Diabetic Nephropathy: Epidemiology,
Prognosis, and Choice of Anticoagulant Therapy]. | In this review we present data on prevalence of atrial fibrillation (AF) among
patients with type 2 diabetes (T2D), diabetic nephropathy and chronic kidney
disease (CKD). Patients with nonvalvular AF and T2D combined with CKD have
elevated risk of both bleeding and thromboembolic complications, as well as of
all ca... |
25,828 | [The Case of Successful Surgical Treatment of a Patient With Thoracic Endograft
Infection in 5 Years After Thoracic Endovascular Aortic Repair]. | We present here a case of successful staged treatment of a patient with
para-aortic abscess that arose 5 years after thoracic endovascular aortic repair
because of thoracic aortic aneurysm. After stabilization of the patient's
condition by intensive antibiotic therapy we performed left-subclavian
extra-thoracic deb... |
25,829 | [Changes of Nonspecific Proteinases and Proinflammatory Cytokines in the
Clinical Course of Acute Myocardial Infarction of Various Severity]. | PURPOSE: to study changes of serum levels of nonspecific proteinases, their
inhibitors, and proinflammatory cytokines during short term observation of
patients with acute myocardial infarction (MI).
MATERIALS AND METHODS: We included in this prospective short-term study 82
patients (27 with uncomplicated non-Q wave ... |
25,830 | [The Association of Gene Polymorphisms of Matrix Metalloproteinases (-9, -12 and
-20) and Collagen Type I Degradation Products With the Remodeling of the Left
Ventricle in Patients With Acute Myocardial Infarction]. | OBJECTIVE: to study associations of polymorphism of the genes MMP9 rs17576,
MMP12 rs2276109, MMP20 rs2245803, COL1A1 rs1800012, COL1A1 rs1107946 with
remodeling of the left ventricle in patients with acute myocardial infarction.
MATERIALS AND METHODS: We examined 84 patients with myocardial infarction (MI).
Type of ... |
25,831 | [The Role of Hepcidin in Formation of Anemia of Chronic Disease and Iron
Deficiency Anemia in Elderly and Old Patients With Chronic Heart Failure]. | BACKGROUND: Literature data on hepcidin (H) level - the main regulator of
systemic iron homeostasis in patients with chronic heart failure (CHF) - are
contradictory. Relationships of H with markers of inflammation elevated level of
which is characteristic of CHF are insufficiently studied. The latter problem
remain... |
25,832 | [Lipid Blood Profile in Old Patients With Ischemic Heart Disease]. | PURPOSE: to assess prevalence of dyslipidemia in patients with ischemic heart
disease (IHD) older than 75 years as well as to evaluate possible associations
between serum lipids and various cardiovascular and other diseases in these
patients.
METHODS: We enrolled in this cross sectional study 555 hospitalized IHD pa... |
25,833 | [Assessment of Efficacy of Combined Pharmacotherapy With Fixed
Perindopril/Amlodipine Combination in Patients With Combined Cardiovascular
Pathology in Outpatient Practice]. | AIM: to study effects of using fixed perindopril/amlodipine combination in
complex treatment of patients with combined cardiac pathology in active
observation mode, in comparison with other angiotensin converting enzyme (ACE
inhibitors) or angiotensin II receptor antagonists (ARA), including free
combination with c... |
25,834 | [Duration and Timing of Initiation of Therapy With Platelet P2Y12 Inhibitors in
the Treatment of Patients With Acute Coronary Syndrome]. | In recent years, the issues of choice of an agent for dual antiplatelet therapy
(DAPT) as well as timing of initiation and duration of DAPT in patients with
acute coronary syndrome (ACS) have been actively discussed. In this article we
present data of major randomized trials of clopidogrel and novel P2Y12
inhibitor... |
25,835 | [Sympathetic Nervous System Activation in Pathogenesis of Development of
Essential Hypertension and Its Role in Target-Organs Damage in Young and Middle
Aged Adults: the Cardioprotective Capabilities of Bisoprolol]. | The article discusses various mechanisms of developmentt and progression of
arterial hypertension in young and middle aged adults. It emphasizes the
predominant role of hypersympathicotonia in the development of the disease in
this category of patients. Various mechanisms are considered, by means of which
the incre... |
25,836 | [Dysfunctional High-Density Lipoproteins: Role in Atherogenesis and Potential
Targets for Phospholipid Therapy]. | In recent years the number of articles on damages of high-density lipoproteins
(HDL) properties in patients with atherosclerosis has sharply increased. First,
it concerns their ability to accept cholesterol (CH) from macrophages - the
basis of antiatherogenic action of HDL. This ability was assessed ex vivo - by
ac... |
25,837 | [Specific Features of Pharmacotherapy of Patients With Chronic Heart Failure and
Preserved Left Ventricular Ejection Fraction]. | The review is devoted to pharmacotherapy of chronic heart failure (CHF) with
preserved left ventricular ejection fraction. In this review we discuss data of
meta-analyzes of randomized clinical trials and observational studies, as well
as the indications for use of inhibitors of the renin-angiotensin-aldosterone
sy... |
25,838 | [The Efficacy of Rivaroxaban in Reducing the Risk of Cardiovascular Events in
Patients with Stable Ischemic Heart Disease and Peripheral Disease. Results of
the COMPASS Trial]. | The article considers modern approaches to the secondary prevention of
cardiovascular events in patients with stable ischemic heart disease (IHD) and /
or atherosclerosis of peripheral arteries (peripheral artery disease - PAD) with
the oral anticoagulant rivaroxaban. The results of the first international
prospect... |
25,839 | [Association of polymorphism 4a/4b and 4b/4b in endothelial nitric oxide
synthase gene and markers of endothelial dysfunction in patients with chronic
heart failure]. | AIM: To examine the association of polymorphism 4a/4b and 4b/4b in endothelial
nitric oxide synthase gene (eNOS) with levels of natriuretic peptide type-C,
endothelin-1 and vasoregulative endothelial function in patients with chronic
heart failure (CHF) depending on the ejection fraction of the left ventricle.
MATER... |
25,840 | [Predictive significance of disturbed water-salt homeostasis in decompensated
chronic heart failure patients]. | AIM: To estimate association between disorders of salt-water homeostasis on
admision and the remote one-year prognosis for patients hospitalized with
decompensated CHF NYHA FC III-IV.
MATERIALS AND METHODS: This prospective study was based on clinical amnestic
data and results of one-year follow-up of 111 consecutiv... |
25,841 | [Response predictors for physical training HFrEF patients]. | PURPOSE: To identify different types and possible predictors of physical
rehabilitation (PR) response in reduced ejection fraction heart failure (HFrEF)
patients, selected on the basis of achievement the lactate threshold during
cardiopulmonary exercising test (CPET).
METHODS: 64 patients, chronic heart failure (CHF... |
25,842 | [Left ventricular systolic dysfunction in young subjects with marfanoid
habitus]. | BACKGROUND: In Marfan syndrome early impairment of left ventricular systolic
function has been reported. Our aim was to evaluate the left ventricular
systolic function in young adults with Marfanoid habitus (MH) (includes
arachnodactylia, dolichostenomelia, high palate, deformations of the thorax).
METHODS: We studi... |
25,843 | [Effect of chronic kidney disease on the formation of diastolic heart
dysfunction in heart failure patients with preserved ejection fraction]. | Chronic kidney disease is observed in most patients with CHF with preserved
ejection fraction (HFpEF) and presents a major risk factor facilitating
development and progression of LV diastolic dysfunction. The review focused on
the effect of chronic kidney disease on intracellular signaling pathways
affecting stiffn... |
25,844 | [Magnetic resonance imaging in patients with implantable devices for treatment
of disturbed heart rhythm: review of the current situation]. | The question of the possibility of MRI scanning in patients with cardiac
implantable electronic devices (CIED) appeared simultaneously with the
introduction of MRI in clinical practice. A lot of in-vitro, in-vivo and
clinical researches were performed to estimate wat going on with CIED in strong
magnetic field and ... |
25,845 | [NGAL as a marker for some extrarenal complications in acute coronary syndrome]. | AIM: To study the role of neutrophil gelatinase-associated lipocalin (NGAL) as a
marker for extrarenal complications in patients with acute coronary syndrome
(ACS).
MATERIALS AND METHODS: For 110 patients with ACS on days 1-3 of hospitalization,
concentrations of NGAL, serum (s-NGAL) and urinary (u-NGAL) NGAL, and N... |
25,846 | [Clinical and cost effectiveness of percutaneous coronary intervention for
patients with chronic coronary artery disease during overnight hospitalization]. | AIM: To evaluate cost effectiveness of coronary endovascular treatment in
patients with stable IHD during "one-night" hospitalization.
MATERIALS AND METHODS: Using the cost-minimization analysis direct medical cost
of coronary endovascular treatment in patients with stable IHD during the
"one-night" hospitalization ... |
25,847 | [The effect of changing of conventional antihypertensive therapy to a triple
fixed combination therapy with rosuvastatin in high cardiovascular risk
patients]. | BACKGROUND: The low efficiency of recommended therapy for reducing
cardiovascular risk (CV) in patients with arterial hypertension even with an
effective blood pressure decrease is often due to the persistence of high blood
cholesterol and arterial stiffness. Among the effective ways to achieve the goal
of therapy ... |
25,848 | [The notion of CHF course stability: Is it acceptable for Russian practice?]. | AIM: To evaluate preparedness of physicians in real clinical practice to strive
for stabilizing the course of CHF by control of clinical and hemodynamic indexes
both in prevention of admission for decompensated CHF and following discharge
from the hospital.
MATERIALS AND METHODS: The study included 750 CHF patients ... |
25,849 | [Relationship Between Degree of Coronary Vascular Bed Involvement and
Characteristics of Stenting With Short-Term and Long-Term Outcomes in Patients
With Acute Coronary Syndrome (Data of the RECORD-3 Registry)]. | It was shown in this retrospective analysis of data from the Russian registry of
acute coronary syndromes (ACS) RECORD-3 that compared with patients in whom
coronary angiography revealed no hemodynamically significant (>50 %) stenosis,
patients with such stenosis in one vessel (with single vessel disease - SVD) and ... |
25,850 | [Quantitative Assessment of Alterations of Reginal Contractility of the Left
Ventricle in Patients With Ischemic Heart Disease]. | BACKGROUND: An important aspect of ischemic heart disease (IHD) diagnosis is the
assessment of alterations of regional contractility (ARC) of the left ventricle.
Speckle tracking imaging is a relatively new diagnostic method used for this
purpose. Aim of this study was to identify optimal parameters of left
ventric... |
25,851 | [Brain Perfusion, Cognitive Functions, and Vascular Age in Middle Aged Patients
With Essential Arterial Hypertension]. | OBJECTIVE: This study aimed to assess the cognitive functions and cerebral blood
flow measured with arterial spin labeling (ASL) and their possible correlations
with vascular age in untreated middle-aged patients with grade 1-2 essential
arterial hypertension (EAH).
METHODS: We examined 73 subjects aged 40-59 years ... |
25,852 | [Influence of Therapy With Fixed Combination of Perindopril and Amlodipine on
Parameters of Elasticity of Main Vessels and Microcirculation in Patients With
Arterial Hypertension and Type 2 Diabetes Mellitus]. | OBJECTIVE: to assess in patients with arterial hypertension and type 2 diabetes
the effect of perindopril / amlodipine fixed combination on arterial wall
stiffness (AWF) and microcirculation, and relationship between AWF parameters
and the state microcirculation.
MATERIALS AND METHODS: We included in this study 30 p... |
25,853 | [New Data on the Localization of the Vasopressin V2‑Receptor in Patients With
Essential Hypertension 2-3 Degree And Healthy Persons]. | AIM: to compare the percentage of endothelial progenitor cells and exfoliated
endothelial cells in the total number of cells of lymphocytic fraction in
patients with essential hypertension (EH) and practically healthy persons, and
to evaluate expression of vasopressin V2 receptor on the endothelial progenitor
cells... |
25,854 | [The State of Vascular Bed, Parenchyma and Perfusion of Lungs in Chronic
Thromboembolic Pulmonary Hypertension According to Data of Subtraction Pulmonary
Angiography]. | AIM: to assess the state of vascular bed, parenchyma, and perfusion of lungs in
patients with chronic thromboembolic pulmonary hypertension (CTEPH) using the
method of subtraction computed tomography (CT).
METHODS: CT pulmonary angiography (CTPA) was performed in 45 patients with
verified CTEPH (18 men, 27 women, ag... |
25,855 | [Anxiety and Depression in Chronic Heart Failure. What Can a Cardiologist Do?]. | AIM: To reveal the probability and duration of the onset of remission of
anxiety-depressive symptoms in patients with CHF III-IV receiving optimal
medicine treatment (OMT) or (OMT), supplemented with the education program and
active outpatient monitoring (OMT + A).
MATERIALS AND METHODS: A secondary analysis of the ... |
25,856 | [Long-Term Statin Adherence in Patients with Stable Angina after Coronary
Stenting]. | PURPOSE: To study adherence to therapy with statins and its relation to
development of cardio-vascular complications (CVC) in patients with stable
angina after elective percutaneous coronary intervention (PCI) at five-year
observation.
MATERIALS AND METHODS: This study comprised 574 patients with stable angina (81
... |
25,857 | [Calcification Patterns of the Components of the Cardiovascular System and Their
Substitutes: Composition, Stucture and Localization of Calcific Deposits]. | Calcification of cardiovascular tissues and biological substitutes results in
abnormal biomechanics, causing stenosis or tissues ruptures. Therefore, the
understanding of calcification pathways will facilitate the development of
strategies for calcification risk reduction. Even though calcification pathways
have be... |
25,858 | [Optimization of digitalis therapy in clinical practice]. | In recent years there has been a marked decrease in cardiac glycosides use in
patients with heart failure in sinus rhythm and atrial fibrillation. The results
of published studies contradict each other. Some of them doubt the favorable
effect of digoxin in patients with heart failure; others refute the increase in
... |
25,859 | [Prevention of periprocedural kidney ingury by loading doses of statins in
elective percutaneous сoronary interventions]. | PURPOSE OF THE STUDY: To compare the effect of loading doses of atorvastatin and
rosuvastatin on the value of the acute kidney injury and acute inflammatory
response to elective percutaneous coronary interventions.
MATERIALS AND METHODS: An open prospective comparative study included 68
patients referred for electiv... |
25,860 | [Calculator "Available prognosis": Method of evaluation for predicting survival
of patients with chronic heart failure and reduced left ventricular ejection
fraction]. | BACKGROUND: A method for predicting one-year survival of patients with heart
failure and reduced ejection fraction (HFrEF) is required to choose a management
tactics and determine indications for high-tech care at the outpatient stage.
AIM: To develop a method for proper prediction of survival of patients with
HFrEF... |
25,861 | [Features of red blood indexes in elderly patients with ischemic heart disease
and pathology of heart valves before and after surgical correction]. | Due to current options of cardiac surgery, operations on the heart of elderly
patients have become routine in specialized cardiosurgical centers. The issue of
pre- and postoperative anemia of different nature is essential in surgical
correction of heart valves and coronary bypass.
AIM: To study indexes of red blood ... |
25,862 | [Evaluation of long-term adverse cardiovascular events risk after elective
percutaneous coronary intervention]. | OBJECTIVE: The aim of our study was to analyze long-term outcomes, to identify
their predictors and to develop a model for determining the risk of long-term
adverse сardiovascular events after elective percutaneous coronary interventions
(PCI).
MATERIALS AND METHODS: A retrospective study included 151 patients 6 yea... |
25,863 | [The quality of treatment of patients with atrial fibrillation, depending on the
index of polymorbidity, preceded hospitalization for acute coronary syndrome]. | The aim of this work was a retrospective assessment of the quality of treatment,
depending on the severity of polymorbidity (PM) in patients with atrial
fibrillation (AF) before admission to acute coronary syndrome (ACS).
MATERIALS AND METHODS: Retrospectively, 105 patients were included in the
analysis (54 men (51,... |
25,864 | [Experience of hospital initiation of sacubitril/valsartan in a female patient
after acute decompensated heart failure]. | The article discusses management of a female patient with chronic heart failure
with reduced left ventricular ejection fraction after an episode of acute
decompensation. Replacing an angiotensin-converting enzyme inhibitor with a
representative of a new angiotensin receptor-neprilysin inhibitor class,
sacubitril/va... |
25,865 | [Anticoagulant therapy for patients with atrial fibrillationin in special
situations: diabetes mellitus and/or chronic kidney disease]. | Conducting anticoagulant therapy for atrial fibrillation, combined with diabetes
mellitus and/or chronic kidney disease, can create certain difficulties for
practicing doctors due to a simultaneous increase in the risk of thromboembolic
and hemorrhagic complications. The presence of diabetes mellitus and renal
dysf... |
25,866 | [Modified method for determining the normal values of the aortic root diameter
in the focus of aortic pathology in individuals with congenital connective
tissue disorders]. | INTRODUCTION: Enlargement of the aortic root of occurs in many cases with
cardiovascular disease, including congenital connective tissue disorders (CCTD),
especially its differentiated and undifferentiated forms (UCCTD). A common
deficiency of the generally accepted methods for diagnosing an aortic root
dilation ma... |
25,867 | [Parameters of clobal longitudinal myocardial deformation and coronary bloodflow
in patients with primary hypothyroidism]. | AIMS: Assessment of global longitudinal strain of left ventricle and coronary
bloodflow in patients with primary subclinical hypothyroidism.
MATERIALS AND METHODS: The study involved 23 women with primary subclinical
hypothyroidism of age from 55 to 75 years. Physical examination, transthoracic
EchoCG, coronary bloo... |
25,868 | [Relationship between levels of sex hormones and response to cardiac
resynchronisation therapy in men]. | AIM: To study the relationship between levels of sex hormones and effectiveness
of cardiac resynchronisation therapy (CRT) in men with chronic heart failure
(CHF).
MATERIALS AND METHODS: The best response to CRT (mean time, 38 [19,0;53,7]
months) was identifed by a maximum decrease in left ventricular end-systolic
v... |
25,869 | [New possibilities of using moxonidin for blood pressure control in female
patients with osteopenia]. | OBJECTIVE: To assess the effect of moxonidine on bone metabolism and bone mineral
density (BMD) in postmenopausal patients with arterial hypertension (AH) and
osteopenia.
MATERIALS AND METHODS: A randomized, open, clinical trial included 114
postmenopausal patients with AH. All participants were evaluated bone
metab... |
25,870 | [Characteristics and clinical associations of arterial stiffness and subclinical
atherosclerosis in patients with rheumatoid arthritis]. | Te aim of the study was to evaluate parameters of arterial stiffness (AS)
(carotid-femoral pulse wave velocity (cf PWV), central pulse pressure (PP),
cardio-ankle vascular index (CAVI) and stiffness gradient between aorta and
brachial artery) and subclinical atherosclerosis (carotid intima-media thickness
(CIMT) and ... |
25,871 | [Anticoagulant therapy in atrial fibrillation with acute coronary syndrome in
real clinical practice according to the total register of acute coronary
syndrome in the Krasnodar Territory]. | OBJECTIVE: to analyze patients with first-time developing atrial fibrillation
(AF), against acute coronary syndrome (ACS), risk factors for arrhythmia,
assessment of patients' adherence to oral anticoagulant therapy 6-24 months
after the ACS episode, according to the total ACS registry for the Krasnodar
Territory.
... |
25,872 | [Long-term Outcomes of Elective Percutaneous Coronary Interventions]. | OBJECTIVE: to analyze long-term outcomes and to develop a model for determining
the risk of long-term adverse сardiovascular events after elective percutaneous
coronary interventions (PCI).
MATERIALS AND METHODS: We included in this study 148 patients, sent from 2009 to
2011 for routine endovascular intervention for... |
25,873 | [Risk of Stroke After Exacerbation of Ischemic Heart Disease: Data of 3‑Years
Follow-up]. | PURPOSE: to analyze possible associations of clinical and genetic factors with
development of ischemic stroke after exacerbation of ischemic heart disease
(IHD).
MATERIALS AND METHODS: The Russian multicenter study aimed at assessment of risk
of unfavorable outcomes after exacerbation of IHD "Exacerbation of IHD: lo... |
25,874 | [How "Real Life" Treatment of Patients With ST-Elevation Acute Coronary Syndrome
Has Changed During Recent Several Years (Data From a Series of the Russian
RECORD Registries)]. | PURPOSE: to assess changes in the management of patient with ST-Elevation (STE)
Acute Coronary Syndrome (ACS) which occurred during recent several years by
means of comparing data from the series of Russian ACS registries RECORD - "old"
(RECORD and RECORD-2, 2007-2011) and "new" (RECORD-3, 2015).
RESULTS: Numbers of... |
25,875 | [Assessment of Outcomes and Treatment Tactics in Patients With Non-ST-Elevation
Acute Coronary Syndrome: Data of Five-Year Follow-up]. | PURPOSE: to study the role of clinical factors and treatment tactics in the
development of adverse outcomes in patients with non-STelevation acute coronary
syndrome (NSTEACS) for five years follow up.
MATERIALS AND METHODS: The study included 415 patients with NSTEACS observed for
60±4 months from the date of discha... |
25,876 | [Cytomegalovirus Infection and Endothelial Function in Patients With Acute
Myocardial Infarction]. | PURPOSE: to study elucidate association of active cytomegalovirus (CMV)
infection with endothelial dysfunction in patients with acute myocardial
infarction (AMI).
MATERIALS AND METHODS: The study included 42 volunteers without ischemic heart
disease (IHD) and 63 patients with AMI. Blood samples for analysis of the
... |
25,877 | [Lung Diffusion Capacity and Efficiency of Pulmonary Gas Exchange in Chronic
Thromboembolic Pulmonary Hypertension]. | AIM: to study lung diffusion capacity and efficiency of pulmonary ventilation in
patients with chronic thromboembolic pulmonary hypertension (CTEPH) depending on
the severity of pulmonary hypertension.
MATERIALS AND METHODS: The study included 139 patients with CTEPH. The
parameters of body plethysmography, lung dif... |
25,878 | [Epicardial Fat and Atrial Fibrillation: the Role of Profibrinogenic Mediators]. | BACKGROUND: Epicardial adipose tissue (EAT) has certain paracrine functions,
which could be associated with proinflammatory and fibrotic changes in
myocardium even in patients without structural heart disease but with atrial
fibrillation (AF).
PURPOSE: to evaluate interrelationship between clinical data, parameters ... |
25,879 | [Metilin Improves Сardiac Function in Rabbits With Chronic Heart Failure]. | AIM: To study effects of intravenous infusion of a cardioprotective drug
metilin, developed at the "National Medical Research Center of Cardiology" on
indices of cardiac function in rabbits in vivo after prolonged administration of
doxorubicin.
MATERIALS AND METHODS: Animals of the experimental group were intravenou... |
25,880 | [Possible Genetic Predictors of Cardiovascular Complications After Coronary
Artery Bypass Surgery]. | PURPOSE: to investigate associations of single nucleotide polymorphisms (SNPs)
rs2046934, rs1126643, rs5918, rs6065, rs4244285; rs4986893 with cardiovascular
complications (CVC) in patients after CABG.
MATERIALS AND METHODS: We enrolled in this study 130 patients with stable
functional class II-IV angina. After CABG... |
25,881 | [Chronic Heart Failure and Diabetes Mellitus: Pathogenesis and Possibilities of
Treatment]. | In this article we present data of scientific studies of prevalence of diabetes
mellitus (DM) among patients with chronic heart failure (CHF), pathogenetic and
risk factors of CHF development patients with DM (hyperglycemia, elevated body
mass index, age, ischemic heart disease, nephropathy, proteinuria, DM duration... |
25,882 | [Endovascular Treatment of Critical Аоrtic Stenosis: Current State of the
Problem and Perspectives]. | The article contains the review of current understanding of the etiology and
pathogenesis of degenerative aortic stenosis, approaches to surgical treatment
depending on various factors, e. g. severity of defect and comorbidity,
description of endovascular techniques (balloon valvuloplasty and transcatheter
aortic v... |
25,883 | [Contrast-Induced Acute R enal Injury After Percutaneous Coronary InterventionI
in Patients With ST-Segment Elevation Myocardial Infarction]. | AIM: To assess frequency and prognostic value of contrast-induced acute kidney
injury (CI-AKI) after percutaneous coronary intervention (PCI) in patients with
ST-elevation myocardial infarction (STEMI).
MATERIALS AND METHODS: We included in this prospective observational study 233
patients with STEMI. Duration of fo... |
25,884 | [Family History of Cardiovascular Disease in Patients With Early Development of
Acute Coronary Syndrome]. | The aim of the study was to analyze clinical features of patients with premature
acute coronary syndrome (ACS) in relation to family history of cardiovascular
disease (CVD) and familial hypercholesterolemia (FH).
MATERIALS AND METHODS: Of 2832 patients included in ORACUL 1 and ORACUL 2
multicenter observational tria... |
25,885 | [The Impact of Effective Therapy With Atorvastatin on the Dynamics of Parameters
of Electrical Instability in Patients with ST-Elevation Myocardial Infarction]. | AIM: To assess the dynamics of parameters of myocardial electrical instability
in patients with ST-elevation (STE) myocardial infarction (MI) treated with
various doses of atorvastatin.
MATERIALS AND METHODS: Patients with STEMI (n=70), who received atorvastatin 20
or 80 mg/day for 48 weeks, were divided into two gr... |
25,886 | [Gender Aspects of Clinical and Functional Associations of Secondary Mitral
Regurgitation in Patients With Ischemic Heart Disease Without Myocardial
Infarction]. | PURPOSE: to identify factors associated with moderate and severe secondary
mitral regurgitation (MR) in ischemic heart disease patients without myocardial
infarction depending on gender.
MATERIALS AND METHODS: From the Register of coronary angiography we selected men
and women with significant coronary stenosis (≥75... |
25,887 | [Fibrogenesis Genes and Susceptibility to Coronary Atherosclerosis]. | OBJECTIVES: To study associations between genes of different functional classes,
including fibrogenesis genes, with coronary atherosclerosis and specific
features of its course.
METHODS: We included in this study 404 patients with confirmed chronic ischemic
heart disease (IHD) who had undergone coronary artery bypas... |
25,888 | [Characteristics of the Renin-Angiotensin-Aldosterone System in Carriers of
Polymorphic Variants of the VDR Gene With Arterial Hypertension and Obesity]. | AIM: to study the renin-angiotensin-aldosterone-system (RAAS) in patients with
polymorphic variants of the vitamin D receptor gene (VDR), arterial hypertension
(AH) and obesity.
MATERIALS AND METHODS: We included in this study 98 patients with stage II-III
AH and obesity (33 men, 65 women, mean age 61.1±9.9 years an... |
25,889 | [Choice of an Optimal Blocker of the Renin-Angiotensin-Aldosterone System in
Patients With Concomitant Arterial Hypertension and Chronic Obstructive
Pulmonary Disease]. | OBJECTIVE: to compare hypotensive and pleiotropic effects of angiotensin II
receptor blocker (ARB) azilsartan medoxomil (AM) and angiotensin converting
enzyme inhibitor (ACEI) fosinopril in patients with concomitant arterial
hypertension (AH) and chronic obstructive pulmonary disease (COPD).
MATERIALS AND METHODS: W... |
25,890 | [Clinical Value of Algorithms of Minimization of Right Ventricular Pacing in
Patients With Sick Sinus Syndrome and History of Atrial Fibrillation]. | PURPOSE: to assess effectiveness of algorithms of minimization of right
ventricular pacing (MRVP) for prevention of progression of atrial fibrillation
(AF), lowering of frequency of hospitalizations due to cardiovascular causes,
and mortality in patients with sick sinus syndrome (SSS) and history of
paroxysmal AF c... |
25,891 | [Social, Demographic and Behavioral Factors and Their Impact on 5-year Survival
in Subjects Aged Over 75 Years in Moscow Population]. | OBJECTIVE: to study the impact of social, demographic and behavioral factors on
5-year survival rate in persons older than 75 years living in Moscow and the
Moscow region.
MATERIALS AND METHODS: We included in this prospective observational study 283
patients (25% men, age 75-98, mean 86.8±4.3 years) after stay at t... |
25,892 | [Informativity of Indicators of the Arterial Wall Stiffness for Screening
Studies]. | OBJECTIVE: comparative assessment of informativity of parameters of arterial
wall stiffness - the cardio-ankle vascular index (CAVI), the augmentation index
(AI) - for solution of problems of screening patients being under threat of
realization of complex impact of metabolic syndrome (MS) and elevated vessel
wall st... |
25,893 | [Day-by Day Blood Pressure Variability: Methodological Aspects, Prognostic
Value, Effects of Antihypertensive Therapy]. | In this article we present problems of prognostic value of day-by-day blood
pressure (BP) variability, its role in development and progression of damage of
target organs in arterial hypertension, and impact on risk of cardiovascular,
cerebral-vascular complications, and mortality. We also discuss methodological
asp... |
25,894 | [Key Points of the 2017 ACC/AHA/HRS Guideline for the Evaluation and Management
of Patients With Syncope]. | The article presents key points of published in March 2017, Guideline for the
Evaluation and Management of Patients With Syncope (A Report of the American
College of Cardiology/American Heart Association Task Force on Clinical Practice
Guidelines, and the Heart Rhythm Society). This document contains summary and
an... |
25,895 | [The clinical features of heart failure in elderly and old age]. | THE AIM OF THE STUDY: To evaluate the prevalence and clinico-functional features
of myocardial dysfunction in persons 65 years or older in the primary care
seting.
MATERIALS AND METHODS: The prospective cohort study "Crystal" included
participants 65 years and older. The arm of "Crystal" study evaluated a random
sa... |
25,896 | [Predictors of acute heart failure in patients with ST-segment elevation
myocardial infarction of the electrocardiogram after PCI]. | BACKGROUND: Despite the PCI in patients with ST-segment elevation myocardial
infarction (STEMI) the development of acute heart failure (AHF) Killip ≥II is
associated with a poor prognosis.
AIM: To identify predictors of the development of AHF and the prognostic value
of AHF in patients with STEMI after PCI.
MATERIAL... |
25,897 | [The role of telocytes in myocardial remodeling and the development of
cardiovascular complications in patients with chronic heart failure after
coronary artery bypass grafting]. | Аim of the study. A study of the role of cardiac telocytes (Tc) in myocardial
remodeling and the effect of changes in their morphology on the clinical outcome
of coronary bypass (CABG) in patients with chronic heart failure (CHF).
MATERIALS AND METHODS: The perioperative period was analyzed in 83 patients (43
men an... |
25,898 | [Respiratory function in patients with chronic heart failure and different
ranges of ejection fraction]. | Spirometric respiratory impairment is a significant and well-studied predictor
for cardiovascular fatality in heart failure. However, reports of the
interrelation between spirometric indexes and structural alterations of the
heart, particularly left ventricular ejection fraction (LVEF), are scarce.
Apparently, the ... |
25,899 | [Effectiveness of control over hemodynamic indexes and prognosis for patients
with CHF and atrial fibrillation in real-life clinical practice]. | BACKGROUND: Earlier studies have demonstrated a high prevalence of atrial
fibrillation (AF) in patients with CHF. It was noticed that tachycardia and
hypotension provoked high risks for cardiovascular mortality. The presence of
arterial hypertension (AH) in CHF patients also impairs life prognosis.
AIM: To determine... |
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