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26,000 | Alterations of the respiratory system in heart failure. | The review discusses mechanisms for the development of the pathology of the
respiratory system in patients with CHF, such as various types of periodic
respiration, pulmonary hypertension due to the pathology of the left chambers of
the heart, and remodeling of the respiratory musculature. The role of chemo- and
bar... |
26,001 | Hypoxia-inducible factor 1 (HIF-1) as a biomarker of acute kidney injury in
patients with acute decompensation of chronic heart failure. | Actuality. Impaired kidney function adversely influences both immediate and
remote prognosis for patients with chronic heart failure (CHF). However, early
detection and prediction of acute kidney injury (AKI) are understudied.The aim
of study was to investigate hypoxia-inducible factor 1 (HIF-1) as a biomarker
for ... |
26,002 | City Center for the Treatment of Chronic Heart Failure: the organiza-tion of
work and the effectiveness of treatment of patients with chronic heart failure. | Actuality. In the Russian Federation, there has been an increase in the number
of patients with chronic heart failure (CHF) of the III-IV functional class, who
are characterized by frequent development of acute decompensation of СHF and
frequent repeated hospitalizations. This dictates the need to create a system of... |
26,003 | C-reactive protein evaluation in communityacquired pneumonia with comorbid
chronic heart failure as criterion of antibiotic prescription. | AIM: To prove that diagnostic algorithm based on additional measurement of serum
C-reactive protein (CRP) for administration of systemic antibacterial therapy
(ABT) to patients with suspected community-acquired pneumonia (CAP) and
concomitant chronic heart failure (CHF) does not influence outcomes of disease.
MATERI... |
26,004 | Features of the clinic and diagnosis of chronic heart failure in patients with
chronic obstructive pulmonary disease. | AIM: To elucidate clinical and diagnostic features of chronic heart failure
(CHF) in patients with chronic obstructive pulmonary disease (COPD).
MATERIALS AND METHODS: The study included 239 patients with COPD and 42 patients
with CHF without COPD. The first subgroup consisted of 60 patients with a
history of myocar... |
26,005 | Heart valve injury due to radiation therapy. | RELEVANCE: Radiation therapy (RT) plays an important role in oncology, improving
the immediate and long-term results of treatment of a number of tumors. One of
the most significant complications of RT are lesions of the heart valves.
OBJECTIVE: To study the variants of valve damage that occur in patients who
receive... |
26,006 | Two-Stage Revascularization in Patients with Acute Myocardial Infarction and
Massive Coronary Thrombosis. | AIM: to investigate safety and angiographic efficacy of two-stage
revascularization with percutaneous coronary intervention (PCI) with stenting
delayed by one day in patients with acute myocardial infarction (MI) and massive
coronary thrombosis.
MATERIALS AND METHODS: We included in this study 12 patients with massi... |
26,007 | Recanalization of Chronic Total Occlusions Using Modern Endovascular Techniques. | PURPOSE: to assess results of percutaneous coronary intervention (PCI) with
contemporary endovascular techniques of recanalization of chronic total coronary
artery occlusions (CTO) in patients with ischemic heart disease (IHD). Occlusion
(CTO) he procedural and in-hospital outcomes of consecutive patients undergoing... |
26,008 | Assessment of Function of the Left Heart Myocardium by Tissue Doppler Imaging
and Speckle Tracking Echocardiography in Patients with Chronic Heart Failure
with Preserved Left Ventricular Ejection Fraction. | AIM: to study myocardial function in patients with chronic heart failure (CHF)
with preserved left ventricular ejection fraction (PEF) by speckle tracking
echocardiography and tissue doppler imaging.
MATERIALS AND METHODS: We examined 80 patients aged 50-70 years with verified
NYHA class I-IIa CHF and PEF due to art... |
26,009 | Blood Pressure Levels and Prevalence of Arterial Hypertension in the Population
of Residents of the Central Region of Siberia Aged 25–45 Years. | PURPOSE: to study blood pressure levels and the prevalence of hypertension in
persons aged 25-45 years in Novosibirsk.
MATERIALS AND METHODS: A cross-sectional population study in one of typical
areas of Novosibirsk was performed in 2013-2016. The study included 479 men and
612 women aged 25-45 years. Arterial hyper... |
26,010 | Remote Ischemic Preconditioning With the Use of Lower Limb Before Coronary
Artery Bypass Surgery With Cardiopulmonary Bypass and Anesthesia With Propofol. | OBJECTIVE: to study potantial of remote ischemic preconditioning (RIP) as method
of cardioprotection during coronary artery bypass surgery with cardiopulmonary
bypass (CPB) and anesthesia with propofol.
MATERIALS AND METHODS: We included in this study 87 patients (7 were excluded)
with ischemic heart disease, hospit... |
26,011 | Vascular Age Concept: Which Approach Is Preferable in Clinical Practice? | AIM: to compare various approaches to estimation of vascular age in patients
from sample of citizens of Saint-Petersburg (SPB) with arterial pressure (AP)
above 130 / 80 mm Hg without history of cardiovascular events.
MATERIALS AND METHODS: Examination of a population sample of SPB citizens
(n=1600) was carried out ... |
26,012 | Simultaneous Percutaneous Coronary Intervention and Endovascular Closure of
Atrial Septal Defect in Adults. | AIM: to assess clinical efficacy and expediency (appropriateness) of
simultaneous single stage combined coronary stenting and closure of atrial
septal defect.
MATERIALS AND METHODS: Of total number of patients who underwent endovascular
correction of atrial septal defect (ASD) (n=91), in 6 (6.6 %) the procedure of
... |
26,013 | Hypolipidemic Therapy and Chronic Kidney Disease: Effects on Cardiovascular
Risks and Renal Dysfunction. | Steady increase in the prevalence of chronic kidney disease (CKD) is a serious
public health problem, since CKD potentially leads to the development of
end-stage renal disease (ESRD) that requires high-cost replacement therapy and
is closely associated with increased risk of developing cardiovascular diseases
(CVD)... |
26,014 | [Polymorphism A1166C of AGTR1 Gene and the State of Intrarenal Blood Flow in
Patients with Essential Arterial Hypertension 1-2 Degrees]. | AIM: to study relationship between genetic disorders and features of intrarenal
blood flow in patients with essential arterial hypertension (AH) of 1-2 degree.
MATERIALS AND METHODS: We examined 100 patients (60 women, 40 men) aged 35 to 58
years with 1-2‑degree essential arterial hypertension (AH) and chronic kidney... |
26,015 | [Central Aortic Pressure: Reference and Diagnostic Values]. | OBJECTIVE: Practical application of central aortic pressure (CAP) parameters is
limited by the absence of generally recognized reference and threshold
diagnostic indices. The purpose of this work is to establish their values in the
general population of Novosibirsk. Materials and Methods. A total of 327 people
were... |
26,016 | [Single Pill Indapamide and Perindopril Arginine Combination: Optimal Coupling
of Vascular Protection and Hemodynamic Risk Factors Reduction in Patients with
Essential Arterial Hypertension]. | OBJECTIVE: to investigate the impact of indapamide / perindopril single-pill
combination (I / P SPC) on arterial stiffness parameters, blood pressure (BP)
level and BP variability (BPV) in middle-aged patients with stage II grade 1-2
essential arterial hypertension (EAH). Materials and methods. We retrospectively
f... |
26,017 | [Lipid Lowering Therapy with Statins in Patients with Heterozygous Familial
Hypercholesterolemia]. | AIM: to analyze adherence of FH patients with familial hypercholesterolemia (FH)
to the statin therapy and reveal factors, which influence it; to assess the
degree of target level of low-density lipoprotein cholesterol (LDLCH)
achievement by FH patients on statin therapy. Materials and methods. We included
in this ... |
26,018 | [Post Radiotherapy Lesions of the Heart Valves. Principles of Diagnosis and
Results of Treatment]. | BACKGROUND: The use of radiation therapy for the treatment of tumors of the
chest сan lead to the development of cardiac pathology, including that of the
valves and coronary arteries.
STUDY AIM: to analyze the specifics of post-radiation lesions of the
valvular apparatus and coronary arteries, and to assess the imme... |
26,019 | [Electrhopysiological Effect of the Polyamine Spermine in Normoxic and Ischemic
Ventricular Myocardium]. | Cytoplasmic polyamines (PA) are involved in control of many cellular functions
and are well known as regulators of so called inward-rectifier potassium ion
channels. Nevertheless, functional significance of extracellular PA in the heart
is poorly elucidated. Aim of this study was to study effects of endogenous PA
s... |
26,020 | [Progress and Problems of Practical Cardiology in Russia at the Present Stage]. | Mortality of the population due to diseases of the cardiovascular system is the
most acute problem in Russia. According to the World Health Organization, the
standardized death rate from cardiovascular diseases in the Russian Federation
remains one of the highest in Europe. This review presents statistical data on
... |
26,021 | [Ghrelin Physiology and Pathophysiology: Focus on the Cardiovascular System]. | Ghrelin is a multifunctional peptide hormone, mainly synthesized by P / D1 cells
of the stomach fundus mucosa. Its basic effect, which is realized via GHS-R1 α
receptor in the arcuate and the ventromedial nucleuses of hypothalamus, is
stimulation of the synthesis of pituitary hormones. Ghrelin is involved in
contro... |
26,022 | [Infective Endocarditis Causing Native and Prosthetic Heart Valve Dysfunction]. | Infective endocarditis (IE) is the disease that has high inhospital mortality.
Heart valves dysfunction - both native and prosthetic - is the primary IE
complication requiring a surgical intervention. The IE causes and its course
have been discussed in this review. In particular, the role of concomitant
infectious ... |
26,023 | [The Clinical use of Stress Echocardiography in Ischemic Heart Disease
Cardiovascular Ultrasound (2017)15:7. Translation authors: Arystan A.Zh.,
Fettser D.V.]. | Stress echocardiography is an established technique for the assessment of extent
and severity of coronary artery disease. The combination of echocardiography
with a physical, pharmacological or electrical stress allows detecting
myocardial ischemia with an excellent accuracy. A transient worsening of
regional funct... |
26,024 | [Evaluation of endothelial dysfunction and the possibility of its correction at
the present stage in patients with cardiovascular diseases]. | The review describes the current understanding of endothelial dysfunction,
methods of its evaluation, and highlights the advantages and disadvantages of
various techniques. The role of nitric oxide and endothelin as important markers
of endothelial dysfunction is shown, and the methods of their determination in
cli... |
26,025 | [Possibilities of estimation of breast cancer targeted therapy cardiotoxicity in
routine clinical practice]. | AIMS: To estimate cardiotoxicity of targeted therapy of breast cancer by the
results of methods of investigation, which are used in routine clinical
practice.
METHODS AND RESULTS: We have made a retrospective analysis of medical
documentation of patients with breast cancer, which are given trastuzumab in
mono regim... |
26,026 | [Impact of Diabetes Mellitus and blood glucose levels on the results of
treatment of patients with ST-elevation myocardial infarction undergoing
percutaneous coronary interventions]. | The aim of this study was to evaluate the impact of diabetes mellitus (DM) and
glucose levels on the results of treatment of patients with ST-elevation
myocardial infarction (STEMI) undergoing percutaneous coronary interventions
(PCIs).
MATERIALS AND METHODS: Data were collected from all patients (n=1280) with STEMI... |
26,027 | [Circadian rhythms of thyroid hormones in patients with ischemic heart disease,
arterial hypertension, and atrial fibrillation]. | AIM: To evaluate the interrelationship between diurnal changes in thyrotropic
hormone (TTH), free triiodothyronine (FT3), and clinical features of IHD in
combination with AH and atrial fibrillation (AF).
MATERIALS AND METHODS: Levels of TTH, FT3, and plasma cortisol were measured in
133 patients with IHD and AH with... |
26,028 | [Blood lipids and angina pectoris (by epidemiological cardiological Rose
questionnaire) in the population of 25-45 years of Novosibirsk]. | The aim of the study was to investigate the prevalence of angina pectoris (AP)
according to the standardized epidemiological questionnaire of Rose in the
population of 25-45 years of Novosibirsk and to identify its association with
some lipid and non-lipid risk factors for coronary heart disease (CHD).
MATERIAL AND ... |
26,029 | [Automatic detection of ventricular and supraventricular wide QRS arrhythmias
using complex of morphological criteria and algorithms]. | AIM: The aim of study is a detection of ventricular and supraventricular wide
QRS arrhythmias using complex of morphological criteria and algorithms by method
of automatic analysis.
MATERIALS AND METHODS: For 100 patients (m/f - 61/39, Me (min; max) - 44.5 (10;
85) years) of researched group the analysis of 14306 si... |
26,030 | [Predictors for development of major cardiovascular events in elderly patients
with severe and extremely severe chronic obstructive pulmonary disease in
combination with early stages of chronic kidney disease]. | The aim of the study was to evaluate efficacy, safety and treatment compliance
for different ASA forms (Aspirin Cardio, Cardiomagnyl and Trombo Ass) in a
6-month study.
MATERIALS AND METHODS: A prospective 6-month open, comparative study originally
included 600 patients with IHD and stable angina who received chroni... |
26,031 | [Association of Strategy of Direct Stenting of Infarct-Related Artery with
Reduction of Mortality in Woman with ST-Elevation Myocardial Infarction]. | Aim of this study was to evaluate the impact of direct stenting (DS) strategy on
the results of treatment of female patients with STelevation myocardial
infarction (STEMI) undergoing percutaneous coronary interventions (PCIs).
MATERIALS AND METHODS: Among 1297 patients with STEMI admitted to the coronary
care unit a... |
26,032 | [Dynamics of Coronary Calcification and Its Association with the Clinical Course
of Ischemic Heart Disease and Osteopenic Syndrome]. | PURPOSE: to study the relationship between degree of calcification of coronary
arteries, osteopenic syndrome, and clinical course of ischemic heart disease
(IHD) during 3-5 years of follow-up in men after coronary artery bypass grafting
(CABG). Materials and methods. We included in this prospective study 111 men
ad... |
26,033 | [Selection of Patients with Resistant Arterial Hypertension for the
Catheter-Based Renal Sympathetic Denervation]. | PURPOSE: elaboration of algorithm for selection of patients with resistant
arterial hypertension (AH) for Catheter-Based Renal Sympathetic Denervation
(CBRSD).
MATERIALS AND METHODS: We examined 284 patients with resistant AH. On stage 1 we
excluded most frequent causes of secondary AH. In 247 patients (86.9 %) we
... |
26,034 | [Progression of Chronic Heart Failure: Prognostic Criteria and Non-Drug
Prevention]. | PURPOSE: to study frequency of progression of chronic heart failure (CHF), to
develop multifactorial models for evaluation of risk of progression, and
measures of non-drug secondary prevention of CHF.
MATERIALS AND METHODS: We included in this study 531 patients with functional
class (FC) I-III CHF (FC I - n=254, FC... |
26,035 | [Visualisation and Radiofrequency Ablation of Sympathetic Innervation Loci in
the Left Atrium in Patients with Paroxysmal Atrial Fibrillation]. | INTRODUCTION: A novel cardiac gamma camera utilizes the radiopharmaceutical
Iodine-123-Meta-iodobenzylguanidine (123I-MIBG) to visualize cardiac sympathetic
innervation. Physiological accumulation of 123I-mIBG provides an anatomical
quantitative determination of the structures of the autonomic nervous system
(ANS) ... |
26,036 | [Decreased Heart Rate Variability in Sickle Cell Anemia as Effect of Pulmonary
Arterial Hypertension]. | Decreased heart rate variability (HRV) is associated with increased mortality
risk in various diseases. The objective of this investigation:to study HRV in
patients with sickle cell anemia (SCA) and to assess the effect of pulmonary
arterial hypertension (PAH) on HRV in these patients. Materials and methods. HRV
re... |
26,037 | [Pressure and Volume Characteristics of the Left Ventriclе in Its Diastolic and
Systolic Dysfunction]. | The Aim of the study was a detailed investigation of pressure volume-loop
(PV-loop) curves in the rat heart during development of
doxorubicin cardiomyopathy.
MATERIALS AND METHODS: Cardiomyopathy in rats has been developed after 4 weeks
doxorubicin administration (2 mg / kg weekly).
RESULTS: Echocardiographic study ... |
26,038 | [Non-Central Influences of α2-Adrenergic and Imidazoline Agonist Interactions in
Isolated ardiomyocytes Cardiac Cells]. | AIM: to investigate the functional interaction of α2-adrenergic and imidazoline
receptors recently identified on the sarcolemma of isolated cardiomyocytes for
regulation of the intracellular calcium and the production of the signal
molecule of nitric oxide (NO).
MATERIALS AND METHODS: experiments were performed on i... |
26,039 | [The Role of Endothelial Dysfunction in the Development of Cardiotoxic Action of
Cytostatics in Patients with Lymphoproliferative Diseases]. | Understanding mechanisms of chemotherapy cardiotoxicity is an important problem
due to the lack of clear understanding of its occurrence. Development of
endothelial dysfunction is considered to be one of possible ways in
implementation of these side effects. The analysis of endothelin-1 and
e-selectin levels in 26 ... |
26,040 | [Myocardial Contractile Function in Patients with Liver Cirrhosis and Syndrome
of Bacterial Overgrowth Syndrome]. | OBJECTIVE: to study myocardial contractile function in patients with liver
cirrhosis and ascites in the presence of bacterial overgrowth syndrome (BOS) and
pathological bacterial translocation.
MATERIALS AND METHODS: We included in this study 59 patients with Child-Pugh
class B and C liver cirrhosis (LC) of various ... |
26,041 | [Type 2 Diabetes Mellitus and Heart Failure: Innovative Possibilities for
Management of Prognosis]. | Type 2 diabetes mellitus (T2DM) has gone beyond the professional interests of
one specialty. T2DM, cardiovascular (CV) diseases and chronic kidney disease,
considered from the standpoint of a single cardio-reno-metabolic continuum,
place a heavy economic burden on society. At the same time, the improvement of
diagn... |
26,042 | [Macrophages and Their Role in Destabilization of an Atherosclerotic Plaque]. | The modern data on structure and the functional activity of macrophages are
presented in the review. It is shown that they are the nonhomogeneous cell
population. Two of their main subpopulations are presented as M1 and M2
phenotypes which perform opposite functions at inflammation development. The
main attention i... |
26,043 | [Intracardiac and Pulmonary Cement Embolism after Percutaneous Vertebroplasty]. | The article presents a clinical case of embolism with bone cement of the right
ventricle of the heart and pulmonary artery after percutaneous vertebroplasty in
a patient aged 63 years. According to the results of a comprehensive examination
using ultrasound and x-ray methods, three foreign bodies were found: in the ... |
26,044 | [Anaemia and iron deficiency in chronic heart failure patients]. | Tis review focused on prevalence of anemia and iron defciency (ID) in CHF and
their effect on the course and prognosis of this condition. Based on evaluation
of numerous laboratory data defnitions of anemia and ID were suggested.
Specifcally, a diagnostic value of measuring serum iron, serum ferritin,
transferrin sa... |
26,045 | [Assessment of myocardial electrical dissynchrony by noninvasive activation
mapping and its role in achieving the success of cardiac resynchronization]. | PURPOSE: To assess and to compare the ventricular myocardium activation patern
obtained by non-invasive epi- and endocardial mapping (NIEEM), as well as
electrocardiographic (ECG) variants of lef bundle branch block (LBBB) and to
estimate the value of these data for the success of cardiac resynchronization
therapy ... |
26,046 | [EPOCHA-D-CHF: gender differences in the prognosis of patients with CHF af-ter
acute decompensation (part 2*)]. | AIM: To study effects of gender differences in clinical and epidemiological
factors on long-term prognosis for patients with acute decompensated heart
failure (ADHF).
MATERIALS AND METHODS: A retrospective, observational analysis of a sample of
patients (n=718) hospitalized with signs of ADHF with subsequent collectin... |
26,047 | [Prognosis of the life of patients with chronic heart failure and atrial
fibrilla-tion, depending on the control of hemodynamic parameters and tolerance
to physical exertion in the background of basic therapy]. | Actuality. In the basic therapy of CHF, drugs that reduce the pulse is one of
the leading places. Target values of heart rate with sinus rhythm are
established. Tere is still no consensus as to which heart rate is ideal in
patients with CHF on the background of the rhythm of atrial fbrillation (AF). Te
study of the... |
26,048 | [Cell therapy in the multimodality treatment of a patient with dilated
cardiomyopathy. A case report]. | We present a 13-years follow-up results in patient with dilated cardiomyopathy.
We performed intracoronary infusion of bone marrow mononuclear fraction in
patient with 4th heart failure functional class in 2005. We observed an
improvement in symptoms (patient had 1st functional class of heart failure)
during 10-yea... |
26,049 | [Effect of Concomitant Chronic Obstructive Pulmonary Disease on Markers of
Collagen Metabolism in Patients with Ischemic Heart Disease]. | AIM: To study parameters of collagen myocardial metabolism in patients with
ischemic cardiomyopathy (ICMP) and to assess the effect of concomitant chronic
obstructive pulmonary disease (COPD) on their levels.
MATERIALS AND METHODS: We examined 130 patients with ICMP (mean age 55.5 [43;
63] years) and 42 patients wit... |
26,050 | [Silent Myocardial Ischemia as a Result of Cardiac Autonomic Neuropathy]. | AIM: to verify the effect of vegetative nervous system on the silent myocardial
ischemia.
MATERIALS AND METHODS: We included in this study 56 patients with functional
class II-III effort angina (22 men and 34 women, age 45-49 years) with silent
myocardial ischemia (SMI). Examination included 24hour blood pressure an... |
26,051 | [Effect of Myocardial Reperfusion on Ischemic Mitral Regurgitation in Patients
with Acute Myocardial Infarction]. | BACKGROUND: During the restoration of blood flow in the ischemic area of the
myocardium, viable cardiomyocytes are damaged over a few minutes of tissue
reperfusion (reperfusion myocardial damage). It is known that ischemic mitral
regurgitation (IMR) develops in 11-19 % of patients who have undergoing
percutaneous c... |
26,052 | [A. N. Bakoulev Scientific Center for Cardiovascular Surgery]. | OBJECTIVE: to assess dynamics of diastolic function for detection of development
of diastolic dysfunction (DD) and it's causes, to evaluate the effect of DD on
prognosis in the postoperative period in patients with acquired heart diseases.
MATERIALS AND METHODS: We included in this study 112 patients with aortic and ... |
26,053 | [Predictors of Progressive Course of Multifocal Atherosclerosis in Patients With
Myocardial Infarction]. | PURPOSE: Determination of clinical and instrumental predictors of progressive
course of multifocal atherosclerosis (MFA) in patients one year after myocardial
infarction (MI), initially having hemodynamically insignificant stenoses of
carotid arteries.
MATERIALS AND METHODS: From database of patients with acute coro... |
26,054 | [Carotid Wall Shear Rate as a Marker of Systemic Atherosclerosis and
Atherosclerotic Cardiovascular Disease]. | AIM: to assess possibility of the use of carotid wall shear rate (WSR) as a
marker of systemic atherosclerosis and atherosclerotic cardiovascular disease
(ASCVD).
MATERIALS AND METHODS: We included into this study 200 patients with different
cardiovascular risk (142 patients already had one or more ASCVD). All patie... |
26,055 | [Epicardial Transplantation of Cardiac Progenitor Cells Based Cells Sheets is
More Promising Method for Stimulation of Myocardial Regeneration, Than
Conventional Cell Injections]. | Today, transplantation of stem / progenitor cells is a promising approach for
the treatment of heart diseases. The therapeutic potential of transplanted cells
directly depends on the method of delivery to the myocardium, which determines
their regenerative properties. It is important for the development of effective... |
26,056 | [Markers of Vascular Wall Fibrosis Metalloproteinase-9 and Tissue Inhibitor of
Metalloproteinases-1 in Patients with Ischemic Heart Disease with and without
Concomitant Type-2 Diabetes Mellitus]. | The prevalence of ischemic heart disease (IHD) and diabetes mellitus type 2 (DM
type 2) is permanently increasing both worldwide and in theRussian Federation.
That is why studies of mechanisms of pathogenesis of both diseases is continuing
for prevention of complications and mortality. DM type 2 contributes a lot to... |
26,057 | [Recommendations on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in
Patients with Atrial Fibrillation (Based on 2018 European Heart Rhythm
Association Practical Guide)]. | Non-vitamin K antagonist oral anticoagulants (NOACs) - direct oral
anticoagulants - are getting the ever-broadening use in clinical practice.
However, many problems related to optimal use of NOACs in specific clinical
situations remain unresolved. European Heart Rhythm Association in April 2018
issued the renovated... |
26,058 | [Antithrombotic Therapy in Atrial Fibrillation and Chronic Ischemic Heart
Disease]. | The review is devoted to the use of antithrombotic therapy in patients with
atrial fibrillation (AF) and chronic ischemic heart disease (IHD). We discuss
data of international registries, meta-analyses assessing possibilities of the
use of oral anticoagulants for secondary prevention of IHD. We present here
results... |
26,059 | [New Targets in Blood Pressure Control: Arguments Pro and Contra]. | The review contains results of analysis of clinical studies on the problem of
defining the target level of the blood pressure (BP). The rationale for
selection the target systolic BP level below120 mmHg was obtained in the SPRINT
study comparing the target levels <120 mmHg and <140 mmHg. A considerably
lower ... |
26,060 | [Complications of the Catheter Treatment of Atrial Fibrillation: Stenosis of All
Pulmonary Veins after Radiofrequency Ablation]. | Radiofrequency ablation is the "gold standard" in atrial fibrillation treatment.
The frequency of complications is about 3.5-3.9 %. The symptomatic pulmonary
vein stenosis is one of the most severe complications. In this report we present
a clinical case of stenosis of all four pulmonary veins after redo catheter
a... |
26,061 | [Statin-associated muscle symptoms: epidemiology, risk factors, mechanisms and
treatment]. | Statins are widely prescribed and the risk of adverse drug reactions of
lipid-lowering therapy is actively discussed, including muscle symptoms. This
review synthesizes the knowledge about the clinical aspects of statin-associated
muscle symptoms, which is important for the practitioner. Potential mechanisms
of the... |
26,062 | [The problem of safety of lipid-lowering therapy]. | This study focused on analysis of current publications evaluating safety of
lipid-lowering therapy. Search for literature was performed on websites of
cardiological societies and online databases, including PubMed, EMBASE, and
eLibrary by the following key words: statins, statin intolerance, lipid-lowering
therapy,... |
26,063 | [Double antiplatelet therapy in patients with acute coronary syndrome after
percutaneous coronary intervention: individual efficacy and hemorrhagic safety
of P2Y12 blockers of ticagrelor and clopidogrel in actual clinical practice]. | AIM: To study the comparative efficacy and safety of clopidogrel and ticagrelor
in the "double" antiplatelet therapy (DATT) in patients with acute coronary
syndrome (ACS) after percutaneous coronary intervention (PCI) in the early and
late periods in real clinical practice, and to assess adherence to treatment.
MATE... |
26,064 | [Factors associated with atrial fibrillation in patients with hypertension and
preserved left ventricle systolic function]. | The objective of our study was to define factors associated with atrial
fibrillation (AF) in patients with hypertension (HTN) and preserved left
ventricle systolic function.
MATERIAL AND METHODS: Overall, 273 consecutive patients with HTN residing in
urban area were included in the study. Patients were divided into ... |
26,065 | [Possibilities of clinical use of ezetimibe Otrio (JSC "AKRIKHIN", Russia) in
patients with high and very high cardiovascular risk who have not reached the
target values of lipid metabolism. Conclusion of the Board of experts]. | This Conclusion of the Board of experts is devoted to the analysis of the
evidence base, the position in modern clinical guidelines, the efficacy and
safety analysis as well as the options of combined therapy with statins and
ezetimibe (Otrio, JSC "AKRIKHIN") in various categories of patients in routine
clinical pr... |
26,066 | [Improvement of outcomes in patients with recent acute coronary syndrome: the
place of PCSK9 inhibitors. The Resolution of National Advisory Board]. | On April 9, 2018, the national advisory board "Improvement of outcomes in
patients with recent ACS: the place of PCSK9 inhibitors" was held in Moscow.
Leading Russian experts in the field of atherosclerosis and lipid-lowering
treatment attended the board. The purpose of the Board was to determine the
place of PCSK9... |
26,067 | [Epidemiology of Arterial Hypertension in Russian Federation - Importance of
Choice of Criteria of Diagnosis]. | PURPOSE: Assessment of prevalence of arterial hypertension (AH), need for
prescription of antihypertensive therapy (AHT), and efficacy of AHT in Russian
population in accordance with novel guideline of the American College of
Cardiology/American Heart Association ("American recommendations") on diagnosis
and treatm... |
26,068 | [The Pathways to Increase the Efficacy of Drug Therapy in Patients with Ischemic
Heart Disease after Coronary Artery Bypass Grafting]. | PURPOSE: to assess drug therapy and achievement of target parameters of
treatment in patients with ischemic heart disease (IHD) during 3-5 years of
follow-up aſter coronary bypass surgery.
MATERIALS AND METHODS: From the initial sample of the coronary bypass surgery
registry (n=680) we selected for this study 111 men... |
26,069 | [Experience with Prasugrel in the Treatment of Patients with Acute Coronary
Syndrome]. | BACKGROUND: Dual antiplatelet therapy (DAPT) with aspirin and one of inhibitors
of P2Y12 receptors (clopidogrel, ticagrelor, prasugrel) is an international
standard of receptors (clopidogrel, ticagrelor, prasugrel) is an international
standard of is an international standard of treatment strategy in patients with
a... |
26,070 | [Systematic Analysis of the Roles of Trace Elements in the Prevention and
Treatment of Chronic Heart Failure]. | Systematic analysis of 3 728 publications on the relationship between
microelement status and chronic heart failure (CHF) was carried out. Three main
areas of research have been identified: 1) magnesium, electrolytes and CHF; 2)
the transcriptional and antioxidant effects of zinc, selenium, copper; 3)
iron-deficien... |
26,071 | [Mitochondrial Antioxidant Plastomitin Improves Cardiac Function in
Doxorubicin-Induced Cardiomyopathy]. | The aim of the study was to ascertain whether the use of plastomitin, the
mitochondrial antioxidant, can affect the development of systolic dysfunction
that occurs in rats after 4 weeks of doxorubicin treatment (2 mg/kg
weekly). Materials and methods. Male Wistar rats weighing 320-380 g were used in
this work. Echo... |
26,072 | [The Analysis of the Causes of Sudden Deaths Among Workers of Locomotive Crews]. | to analyze causes of sudden death (SD) of workers of locomotive crews. Materials
and methods. We performed the retrospective analysis of SDs of employees of
Joint Stock Company ( JSC) "Russian Railways" for the period 2009-2017 (total
119 cases). Results. As a rule, the combination of risk factors of development
of... |
26,073 | [Comorbidity of Chronic Obstructive Pulmonary Disease and Cardiovascular
Diseases: Place of Therapy with Modern β-Adrenoblockers]. | Chronic obstructive pulmonary disease (COPD) is the fourth largest cause of
worldwide mortality. Presence of comorbidities is registered in 96% of COPD
patients. The most important of these are cardiovascular diseases (coronary
artery disease, arterial hypertension, chronic heart failure), which contribute
to COPD... |
26,074 | [The Nephrological Aspects of the Use of Rivaroxaban and Other Direct Peroral
Anticoagulants in Non-Valvular Atrial Fibrillation]. | Chronic kidney disease (CKD) is a powerful cardiovascular risk factor, its
presence is accompanied by an increased risk of hospitalization for exacerbation
of chronic heart failure (CHF), adverse outcomes in myocardial infarction, and
cardiovascular mortality. Among the adverse events, an increased risk of atrial
f... |
26,075 | [Possibilities of Computed Tomography of the Heart in Risk Stratification and
Determination of Optimal Strategy of Primary Prevention of Cardiovascular
Complications of Atherosclerosis]. | Modern strategies of primary prevention of cardiovascular complications of
atherosclerotic etiology are presented in this article: traditional approach
based on assessment of risk of development of complication and coming to replace
it concept of prevention based on direct application of results of prospective
clin... |
26,076 | [A Case of Successful Thrombolysis on the Verge of a Reperfusion Revolution in
Coronary Cardiology and Vascular Neurology]. | Thrombolytic therapy (TLT), as a method of treatment, began to develop in the
second half of the 50s of the last century. At that time, there was an
accumulation of data on its effectiveness, side effects and contraindications,
as well as the development of fibrinolytic drugs, such as fibrinolysin,
streptokinase, u... |
26,077 | [Opportunities and Problems of Analysis of Mortality from Myocardial Infarction
According to Medical Certificates of Death (on the Example of the Tula Region)]. | AIM: to analyze the quality of completion medical certificates of death (MCD) of
residents of the Tula region, in which in 2017 acute and subsequent myocardial
infarction (MI) was listed as the underlying cause of death (UCD) or as multiple
causes of death (MC).
MATERIALS AND METHODS: From the electronic database (D... |
26,078 | [Own and Parental Predictors of Hypertriglyceridemia in Children of Persons with
Early Ischemic Heart Disease]. | AIM: to elucidate predictors of high level of basal triglycerides (TG) in blood
of children of persons with early (onset: men ≤55, women ≤60 years) ischemic
heart disease (EIHD).
MATERIALS AND METHODS: We examined 316 families: patients (probands) (n=295;
77.9 % after MI) with EIHD, their spouses (n=219; 83.1 % wome... |
26,079 | [Specific Features of the Course of Acute Coronary Syndrome in Patients with
Newly Developed Atrial Fibrillation in Clinical Practice According to the Data
of the Register of Acute Coronary Syndrome]. | AIM: to elucidate risk factors of development of atrial fibrillation (AF) in
patients with acute coronary syndrome (ACS), and to assess of patient's
adherence to oral anticoagulant therapy (OAT) during 12 months after ACS episode
according to the data of the Total ACS Registry for the Krasnodar Territory.
MATERIALS ... |
26,080 | [An Experience of Meldonium Use in Patients with Ventricular Arrhythmias of
Ischemic Genesis]. | Ischemic heart disease (IHD) is often accompanied by cardiac rhythm disturbances
particularly ventricular arrhythmias (VA) and their appearance in both chronic
and acute forms of IHD is usually regarded as dangerous signal requiring the use
of antiarrhythmic drugs. An important addition to hemodynamic therapy can be... |
26,081 | [Clinical Features of Comorbid Cluster and Premorbidly Manifestations in
Patients with High Vascular Risk in the Middle Age Category with the Presence of
Multifocal Atherosclerosis]. | OBJECTIVE: to study clinical and cluster features of cardiovascular burdening
taking into account the comorbid polymorbid background in patients of middle age
(45-60 years) with the presence of multifocal atherosclerosis (MFA).
MATERIALS AND METHODS: Patients were examined in the Regional Vascular Center of
Ufa (RVC... |
26,082 | [Detection of Antigens of Cardiotropic Viruses in Atherosclerotic Plaques in
Patients with Fatal Myocardial Infarction]. | AIM: To assess the frequency of detection of cardiotropic virus antigens in
coronary artery atherosclerotic plaques in patients with fatal myocardial
infarction (MI).
MATERIALS AND METHODS: We examined fragments of coronary plaques of 12 patients
with fatal type 1 MI. Immunohistochemistry (IHC) of plaques was perfor... |
26,083 | [The Method of Assessment of the Population Risk of Cardiovascular Diseases:
Rationale and Examples of Application]. | Epidemiological studies in cardiology often are confronted with the need of
modeling the population dependence of the development of cardiovascular diseases
(CVD) on a complex of influencing risk factors (RF). A method for assessment the
CVD population risk is proposed, the calculation of which assumes the populatio... |
26,084 | [In-hospital Myocardial Infarction: Scale of the Problem]. | All cases of acute myocardial infarction (AMI) can be divided into
outpatient-onset AMI and in-hospital-onset AMI depending on the place and
circumstances of their development. In this review we consider the problem of
in-hospital AMI. Special attention is paid to specific features of its clinical
manifestations an... |
26,085 | [Exhaled Breath Analysis in Diagnostics of Cardiovascular Diseases]. | Exhaled breath analysis is a novel tool for diagnostics of different diseases.
Taking into account the secretory function of the lungs, the composition of
exhaled breath is different in physiological and pathological conditions. In
this review we consider of some substances which content vary in cardiovascular
dise... |
26,086 | [Clinical Capabilities and Limitations in the Use of Modern Technologies in
Echocardiography]. | Transthoracic echocardiography is the most frequently used method for detection
of impaired contractility of the left ventricle. In most cases, assessment of
contractility is carried out visually "by eye", what increases its subjectivity,
is operator-dependent in nature and requires a high level of clinical training... |
26,087 | [Analysis of cardiovascular safety of novel glucose-lowering medications]. | In 2008 the Food and Drug Administration has revised approval process for new
antidiabetic agents and introduced a requirement to demonstrate the
cardiovascular safety in an international multicenter trial. Currently
cardiovascular outcome trials of dipeptidyl peptidase-4 (DPP-4) inhibitors
(SAVOR-TIMI53, EXAMINE a... |
26,088 | [Novel Biomarkers of Pulmonary Hypertension]. | Pulmonary hypertension (PH) is a clinical syndrome characterized by a
progressive increase in pulmonary vascular resistance (PVR), which leads to
remodeling of the right ventricle (RV), right heart failure and premature death
of patients. Early diagnosis and monitoring of disease progression are crucial
for making ... |
26,089 | [Mechanisms of exercise intolerance in patients with heart failure and preserved
ejection fraction. Part I: The role of impairments in the left heart chambers]. | During exercise an increase in oxygen delivery to working muscles is achieved
through well‑coordinated interaction of many organs and systems: the heart,
lungs, blood vessels, skeletal muscles, and the autonomic nervous system. In
heart failure with preserved left ventricular ejection fraction, all mechanisms
invol... |
26,090 | [Lipid spectrum and function of kidneys before and after liver transplantation]. | BACKGROUND: In patients after liver transplantation cardiovascular complications
is the third main reason of death afer allograf failure and infections. The most
important factors in the development of cardiovascular diseases are dyslipidemia
and impaired renal function. The aim of the study was to investigate the l... |
26,091 | [Quality of life in patients with heart failure with preserved ejection fraction
and the bendopnea symptom]. | The study of quality of life (QOL) in patients with CHF with preserved LVEF
(left ventricular ejection fraction) and a symptom of bendopnea with different
levels of salt intake. Materials and methods. The study included 66 patients.
The main symptoms of CHF were edema in 54.5% of cases, dyspnea in 77% of cases,
asci... |
26,092 | [Stability of chronic heart failure from the position of a doctor and a patient:
in search of contact points]. | Actuality. The results of the EPOCH study showed that in 16 years in the Russian
Federation the number of patients with chronic heart failure (CHF) of I-IV FC
increased significantly. The main objectives of the treatment of CHF are the
stabilization of the patient's condition and the reduction of the risks of
cardi... |
26,093 | [Indicators of the left ventricular-arterial coupling interaction in chronic
forms of ischemic heart disease: relationships of the protradenomedullin and
N-terminal probrain natriuretic peptide]. | PURPOSE OF THE STUDY: Analyze the parameters of the interaction between the left
ventricle and the arterial system in patients with chronic forms of coronary
heart disease and to identify relationships with levels of proadrenomedullin
(MR‑proADM) and N‑terminal precursor of the brain natriuretic peptide B
(NT‑proBN... |
26,094 | [Clinical features and prognosis in heart failure patients with chronic
obstructive pulmonary diseases]. | BACKGROUND: Multimorbidity is a specific characteristic of the modern patient
with chronic heart failure (CHF) which significantly changes clinical course,
prognosis of the syndrome, leads to socio‑economic losses and makes significant
adjustments to treatment tactics. The goal is to study the clinical features and ... |
26,095 | [Chronic right ventricular failure in a patient with diffuse toxic goiter and
alcoholic cirrhosis of the liver: case description]. | We present a case of a patient with pronounced edematous‑ascitic syndrome.
Initially, its causes were considered to be alcoholic cardiomyopathy (right
ventricular failure) with heart rhythm disturbances and liver cirrhosis.
Targeted treatment had a low clinical effect, which served as a basis for
revising the diagno... |
26,096 | [Pulmonary congestion by lung ultrasound in decompensated heart failure:
associations, in-hospital changes, prognostic value]. | BACKGROUND: Recently lung ultrasound (LUS) based on B-lines measurement has been
proposed as an effective tool for assessment of pulmonary congestion (PC) in
patients with decompensated heart failure (DHF).
OBJECTIVE: to assess the incidence, in-hospital changes and prognostic
significance of PC assessed by LUS in D... |
26,097 | [Early Invasive Strategy in Patients over 75 Years with Acute Coronary Syndrome.
A Single Center Study]. | OBJECTIVE: to assess the clinical status, comorbidities, complications,
in-hospital mortality and its structure in dependence of age and type of acute
coronary syndrome (ACS) in case of early invasive strategy of ACS management.
MATERIALS AND METHODS: we included in this retrospective study data of all
patients (n=1... |
26,098 | [Clinical Course and Predictors of Ischemic Mitral Regurgitation in Patients
with Myocardial Infarctions of Different Localizations]. | PURPOSE: to assess the clinical course of ischemic mitral regurgitation (IMR) in
patients with myocardial infarction of different localizations and reveal its
mechanisms and predictors.
MATERIALS AND METHODS: We enrolled in this study patients with first
inferoposterior myocardial infarction (IPMI) (n=77), and anter... |
26,099 | [Electrophysiological Cardiac Parameters and Results of Antiarrhythmic Treatment
in Patients with Paroxysmal Atrial Fibrillation (Lone and Associated with
Arterial Hypertension)]. | PURPOSE: to assess cardiac electrophysiological parameters in patients with
paroxysmal atrial fibrillation (AF), lone or with concomitant arterial
hypertension (AH), and their prognostic significance relative to treatment
effectiveness.
MATERIALS AND METHODS: We included in this study 184 patients with paroxysmal AF... |
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