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25,900 | [Fractalkine level in chronic heart failure of varying severity]. | Purpose of research. To examine the level changes of fractalkine in patients
with chronic heart failure (CHF) depending on the ejection fraction of the left
ventricle and the stage of the disease.
MATERIALS AND METHODS: In total 340 people were examined. Of these, 280 patients
with CHF divided into groups depending ... |
25,901 | [Anemia of chronic disease and iron deficiency anemia: Comparative
characteristics of ferrokinetic parameters and their relationship with
inflammation in late middle-aged and elderly patients with CHF]. | AIM: To perform a comparative analysis of anemia of chronic disease (ACD) and
iron-deficiency anemia (IDA) in late middle-aged and elderly patients with
chronic heart failure (CHF) by ferrokinetic parameters, inflammation indexes,
and their associations.
MATERIALS AND METHODS: 65 patients with ischemic heart disease... |
25,902 | [Impact of Arterial Hypertension on the Formation of the Risk of Mortality.
Results of a 27‑Year Prospective Study]. | OBJECTIVE: to investigate the impact of arterial hypertension (AH) on formation
of the risk of total and cardiovascular mortality.
MATERIALS AND METHODS: The 27‑year cohort prospective study was conducted on the
sample of unorganised population of Tomsk (n=1 546, age 20-59 years, 630 men,
916 women). At the first st... |
25,903 | [Predictors of Obstructive Sleep Apnea Syndrome According to Results of Clinical
Examintion and Ambulatory Blood Pressure Monitoring]. | OBJECTIVE: to determine the predictors of obstructive sleep apnea syndrome
(OSAS) basing on clinical examination, results of night pulse oximetry, daily
dynamics of heart rate and blood pressure (BP) in men with newly diagnosed
arterial hypertension (AH).
MATERIALS AND METHODS: Men (n=197, mean age 40.1 ± 8.4 years)... |
25,904 | [Combined Therapy of Arterial Hypertension With Triple Fixed-Dose Combination of
Amlodipine/Indapamide/Perindopril Arginine in Real Clinical Practice: the
Organization and the Main Results of the DOKAZATEL'STVO (Proof) Study]. | AIM: to assess antihypertensive efficacy of the fixed-dose
amlodipine/indapamide/perindopril arginine combination in hypertensive patients
in real clinical setting.
METHODS: We included in the 3‑month clinical program 1 599 patients with
arterial hypertension (AH) (38.8 % men, mean age 61.6±10 years). Primary
outco... |
25,905 | [Dynamics of Quality of Life in Patients With Aortic Stenosis After Aortic Valve
Replacement With a Biological or Mechanical Prosthesis]. | OBJECTIVE: To assess dynamics of the quality of life (QOL) in patients of the
older age group of with initial aortic stenosis in 1, 3, and 5 years after
replacement of the aortic valve (AV) with biological or mechanical prosthesis.
MATERIALS AND METHODS: QOL was assessed in 282 patients who underwent aortic
valve re... |
25,906 | [Left Ventricular Myocardial Hypertrophy as a Result of Arterial Hypertension
Among Mountain Shoria Population. The Role of Genetic Polymorphism]. | OBJECTIVE: to establish associations of candidate genes ACE, AGT, AGTR1, ADRB1,
ADRA2B, MTHFR and NOS3 polymorphisms with left ventricular myocardial
hypertrophy (LVH) in patients with arterial hypertension (AH) among the
indigenous (the Shors) and non-indigenous population of Mountain Shoria.
MATERIALS AND METHODS:... |
25,907 | [Clinical-Epidemiological Program of Studying Psychosocial Risk Factors in
Cardiological Practice in Patients With Arterial Hypertension and Ischemic Heart
Disease: First Results of a Multicenter Study in Russia]. | BACKGROUND: More than 10 years passed since conduction of the first
clinical-epidemiological study of prevalence of psychosocial risk factors (PSRF)
in patients with arterial hypertension (AH) an/or ischemic heart disease in
Russian Federation.
PURPOSE: to assess current prevalence of PSRF in patients with AH/CHD an... |
25,908 | [Metabolomic Profiling of Patients With Cardiovascular Diseases]. | Cardiovascular diseases (CVD) are the main cause of death worldwide. A broad
study of the pathogenetic mechanisms of the CVD onset and progression has led to
understanding of the importance of endothelial dysfunction (ED) in these
processes. During recent years intensive work has been conducted in the
direction of ... |
25,909 | [Atrial fibrillation as Risk Factor for Development of Cognitive Function
Impairment and Dementia. Potential of Anticoagulant Therapy in Their
Prevention]. | This article presents an overview of data of Russian and foreign literature on
possible associations between cognitive impairment and atrial fibrillation (AF).
It includes modern classification of cognitive impairment, mechanisms of the
effect of AF on cognitive functions and development of dementia, recommendations... |
25,910 | [Double Blockade of Aldosterone Receptors as a Method of Elimination Negative
Effects of Non-Steroidal Anti-Inflammatory Drugs in Chronic Heart Failure]. | The article deals with the dynamics of echocardioscopy indices during 1.5 years
in a patient who underwent an acute myocardial infarction (MI). Two months after
the MI left ventricular (LV) end-diastolic size and LV volume were 61 mm and 190
ml, respectively; LV ejection fraction (EF) was 42%. At the background of
... |
25,911 | [Vascular Complications Of Cancer Chemotherapy]. | Development and use of new anticancer drugs has resulted in the improving of
5‑year survival rates in patients with cancer. However, many of the modern
chemotherapies are associated with cardiovascular toxicities that increases
cardiovascular risk in cancer patients, including hypertension, heart failure,
thrombosi... |
25,912 | [Physical activity and physical training as method of prevention of
cardiovascular diseases]. | A growing body of data demonstrates that exercise capacity is a potentially
stronger predictor of mortality than established risk factors such as smoking,
hypertension, obesity, high cholesterol, and type 2 diabetes mellitus.
Individuals who maintain a regular program of PA that is longer in duration, of
greater in... |
25,913 | [Thrombosis in patients with malignancy]. | Thrombosis traditionally considered as a complication of cardiovascular disease,
however, this problem until recently was rarely taken into account in the
presence of cancer. Although the association between cancer and thrombosis has
been known almost 150 years ago, awareness of the impact of thrombotic
complicatio... |
25,914 | [Comorbidity and polymorbidity - a modern interpretation and urgent tasks facing
the therapeutic community]. | The article presents an overview of data on polymorbidity. It is shown that
polymorbidity is associated with higher mortality, disability, side effects of
treatment, increased use of health system resources, and also with a lower
quality of life. The issues of effective treatment of people with multiple
chronic dis... |
25,915 | [Prognostic markers for the development of adverse outcomes in patients with
chronic obstructive pulmonary disease and chronic heart failure]. | AIM: To identify markers of adverse outcomes in patients with a combination of
chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF).
MATERIALS AND METHODS: 35 patients with COPD (without an anamnesis of coronary
heart disease), 68 patients with COPD and CHF, 28 patients with CHF of ischemic
g... |
25,916 | [Clinical and demographic features of patients with stroke and atrial
fibrillation]. | BACKGROUND: Stroke takes the second place among all causes for cardiovascular
death and the first place in mortality and disability among other nervous system
diseases. Atrial fibrillation (AF) is presently is a commonly recognized,
independent risk factor for ischemic stroke, which fivefold increases the risk
of a... |
25,917 | [Falling risk factors in patients with arterial hypertension 55+ years old]. | Arterial hypertension (AH) is the most prevalent cardiac risk factor in old
patients. Falls-related complications includes increased disability and
mortality, decreased activity levels, quality of life, and overall health
status. So falls are an important health problem. The aim of our study was to
study falls in p... |
25,918 | [Arterial Hypertension and Methylenetetrahydrofolate Reductase C677T Gene
Polymorphism]. | OBJECTIVE: to determine the association of polymorphisms of C677T
methylenetetrahydrofolate reductase (MTHFR) gene with essential arterial
hypertension (EH) in the group of patients of Belarusian ethnicity.
METHODS: The clinical examination and molecular genetic study of the
polymorphism C677T of MTHFR gene by polym... |
25,919 | [Changes of Content of Matrix Metalloproteinases and Their Tissue Expression in
Various Types of Atherosclerotic Plaques]. | AIM: to investigate diagnostically significant for atherosclerotic plaques (ASP)
of various types parameters of activity of matrix metalloproteinases (MMP-3,
MMP-7, MMP-9) in homogenates, as well as tissue expression of MMP-2, MMP-9 and
collagen type IV.
MATERIALS AND METHODS: We included in this study 54 men with c... |
25,920 | [Analysis of Relationship Between Parameters of Arterial Stiffness and Lipid
Profile in Patients With Metabolic Syndrome]. | AIM: to elucidate relationships between parameters of arterial stiffness
(carotid-femoral pulse wave velocity [cfPWV] and cardio-ankle vascular index
[CAVI]) and standard lipid profile parameters in patients with metabolic
syndrome (MS).
MATERIALS: We included in this study 100 subjects (45 men, 55 women) aged 40-70... |
25,921 | [Prediction of Risk of Calcification of Heart Valve Bioprostheses on the Basis
of Comprehensive Assessment of Recipients Clinical Factors and Their Compliance
With Therapy]. | PURPOSE: The development of the prediction methods of calcification risk of
heart valve bioprostheses (BP) based on comprehensive assessment of the impact
of clinical factors of the recipients and their adherence to medication.
MATERIALS AND METHODS: We performed a retrospective study of clinical status and
adherenc... |
25,922 | [Preventive Counselling With the Use of Remote Technologies Provides Effective
Control of Metabolic Risk Factors in Patients With High and Very High
Cardiovascular Risk]. | PURPOSE: to assess the impact of preventive counseling with focus on diet
modification on lipid and metabolic parameters in patients with high / very high
cardiovascular (CV) risk who visited Health centers.
MATERIALS AND METHODS: This was a prospective randomized controlled study of
patients aged 40 to 65 years wit... |
25,923 | [Ischemic Heart Disease in Subjects of Young Age: Current State of the Problem:
Prevalence and Cardio-Vascular Risk Factors]. | Ischemic heart disease (IHD) occurring at age less than 55 in men and less than
65 years in women is designated as premature IHD. However, in different studies
these age limits vary from 35 years to 65 years. Among the population of working
age in the Russian Federation mortality from IHD is several times higher tha... |
25,924 | [Cognitive Disorders and Dementia in Old Patients With Arterial Hypertension]. | The article describes the definition of dementia, its diagnostic criteria,
classification. Differences in the pathogenesis and clinical manifestations of
different types of dementia are considered. The issues of interrelation of
arterial hypertension and the risk of development of cognitive disorders and
dementia i... |
25,925 | [Impact of Glycemic Variability on Cardiovascular Risk in Diabetes]. | A growing body of evidences indicates the role of increased glucose variability
(GV) as an independent cardiovascular risk factor in diabetes. It has been shown
that high GV is associated with coronary and carotid atherosclerosis in diabetic
subjects. The impact of enhanced glycemic fluctuations on vascular wall is ... |
25,926 | [Novel Possibilities in Pharmacotherapy of Patients With Chronic Heart Failure]. | In this article we have described clinical pharmacology and data of clinical
studies of an innovational drug valsartan + sacubitril in patients with chronic
heart failure (CHF). The use of supramolecular complex valsartan + sacubitril
allows to elevate quality of life and improve prognosis of patients with CHF.
Hig... |
25,927 | [Clinical Case of Successful Nephrectomy and Stenting of the Coronary Arteries
in Acute Period of Myocardial Infarction in a Patient With Kidney Cancer]. | We describe in this case report the clinical situation of development of massive
macrohematuria at the background of dual antiplatelet therapy in a patient in
the acute period of myocardial infarction with an established diagnosis of
kidney cancer and a burdened cardiac anamnesis. Despite the high anesthetic and
op... |
25,928 | [Analysis of the interrelation between immune factors and inflammatory markers,
and the course of chronic heart failiure in patients with rheumathoid
arthritis]. | This review presents relevant information about development and course of
chronic heart failure (CHF) associated with rheumatoid arthritis (RA). One of
the most discussed issues is the effect of systemic inflammatory process on
prognosis of CHF. The review focused on current evidence for significance of
this comorb... |
25,929 | [Results of 3 years work of the Russian hospital register of chronic heart
failure (RUssian hoSpital Heart Failure Registry - RUS-HFR): relationship
between management and outcomes in patients with chronic heart failure]. | AIM: To analyze management and outcomes in patients with CHF managed by
specialists in heart failure (HF) or general cardiologists/physicians in
real-life clinical practice.
MATERIALS AND METHODS: Survival rate, rehospitalization rate, general health
condition, and the administered therapy were evaluated for HF pati... |
25,930 | [Prognostic value of liver stiffness in decompensated heart failure: results of
prospective observational transient elastography-based study]. | OBJECTIVE: There is growing evidence that liver stiffness (LS) in decompensated
heart failure (DHF) is related to congestion, however data about its impact on
outcomes are limited. The aim of the study was to evaluate associations and
long-term prognostic significance of LS measured by transient elastography (TE)
i... |
25,931 | [Role of ST2 biomarker for the evaluation of myocardial remodeling in patients
with ischemic heart failure with preserved ejection fraction]. | AIM: 1) To study the role of soluble ST2 (sST2) in evaluation of left
ventricular (LV) myocardial remodeling and 2) to evaluate the predictive value
of sST2 for development of adverse cardiovascular events (CVE) during 12 months
following myocardial revascularization in patients with ischemic heart disease
(IHD) an... |
25,932 | [Neutrophil gelatinase-associated lipocalin for early diagnosis of acute kidney
injury in patients with acute decompensated heart failure]. | BACKGROUND: the incidence of acute kidney injury (AKI) is high in patients with
acute decompensated heart failure (ADHF) and is linked with increased morbidity
and mortality rates. Predictive biomarkers of AKI could allow improve outcomes
in AKI.
PURPOSE: to evaluate the value of serum neutrophil gelatinase-associat... |
25,933 | [Significance of comorbidity for patients with chronic lymphocytic leukemia]. | BACKGROUND: Chronic lymphocytic leukemia (CLL) remains an uncurable disease, in
which the age, number and severity of comorbidities primarily determine the
choice of therapeutic tactics and objectives.
AIM: To evaluate actual comorbidity and polymorbidity in patients with CLL and a
possible relationship between the ... |
25,934 | [Significance of adipose tissue mass for the clinical course of pneumonia
associated with decompensated CHF]. | BACKGROUND: Pneumonia is one of most important causes of in-hospital mortality
in patients with decompensated chronic heart failure (CHF).
AIM: To evaluate the effect of adipose tissue mass and body weight index (BWI)
on prognosis for patients with communityacquired pneumonia and decompensated
CHF.
MATERIALS AND MET... |
25,935 | [ADP-Induced Recalcified Blood Clotting Time as a Marker of Rethrombosis Risk
and Effectiveness of Antiplatelet Therapy in Acute Coronary Syndrome]. | PURPOSE: to assess the possibility of the use of ADP induced blood-clotting time
measurement in clinical practice prognostication of the course of acute coronary
syndrome (ACS) and assessment of effectiveness of antiplatelet therapy (APT).
MATERIALS AND METHODS: We enrolled in the study 163 male patients admitted to ... |
25,936 | [Structural and Functional Characteristics of the Heart in Patients With
"Constrictive", "Pseudo-Normal" and "Restrictive" Types of the Left Ventricular
Diastolic Dysfunction]. | PURPOSE: to study structural functional characteristics of the heart in patients
with various types of abnormalities of diastolic function (DF) based on data
obtained at stress echocardiography (stress EchoCG) and echocardiographic
indexes of myocardial deformation.
MATERIALS AND METHODS: We included in this study 1... |
25,937 | [Characteristics of Disturbances of Heart Rhythm and Conduction Among Patients
Attending Consultation of a Cardiologist at Ambulatory Stage]. | We included in this study 652 patients with persistent disturbances of heart
rhythm and conductiion who attended a cardiologist of the consulting center
during 2 years. Analysis of results of examination of these patients was aimed
at identification of possible etiologic factors of the appearance of
arrhythmias. In... |
25,938 | [Common Carotid Intima-Media Thickness, Levels of Total and High-Molecular
Weight Adiponectin in Women With Abdominal Obesity]. | OBJECTIVE: to investigate influence of different forms of adiponectin on carotid
intima-media thickness (CIMT) in women with abdominal obesity (AO) in
St.‑Petersburg. It has been recognized before that AO is associated with
cardiovascular diseases, including atherosclerosis, but mechanism of this
association remain... |
25,939 | [Types of Conduction Disturbances in Pulmonary Veins]. | Recently, the notion that in 60-80 % of cases the origin of the pulmonary veins
(PV) is the place of origin of atrial fibrillation (AF) has become widespread.
It has been shown that in this area, under the action of norepinephrine (HA), in
the absence of stimulation, an intrinsic rhythm appears. Using two-channel
m... |
25,940 | [Angiographic Results After Coronary Artery Bypass Grafting]. | The main place among cardiovascular diseases takes coronary heart disease. The
number of coronary artery bypass surgery increases every year. The large number
of coronary artery bypass grafting (CABG) performed worldwide. The need for
assessment of grafts patency is enormous.
OBJECTIVE: We are performed analyze of g... |
25,941 | [Early Markers of Cardiovascular Risk in Women With Hereditary Burdening by
Cardiovascular Diseases]. | PURPOSE: to identify early markers of development of cardiovascular diseases
(CVD) in women.
MATERIALS AND METHODS: Female firstdegree relatives from 39 families formed 2
groups: families (n=19) containing mothers with arterial hypertension (AH)
(group 1) and healthy daughters (group 1a); families (n=20) containing ... |
25,942 | [The Role of Lipoprotein(a) in the Development of Peripheral and Carotid
Atherosclerosis]. | Lipoprotein(a) [Lp(a)] consists of an LDL-like particle in which the
apolipoprotein B100 is covalently bound to apolipoprotein(a) by a single
disulfide bond. Lp(a) is synthesized in the liver and its plasma concentration
varies from 0 to 400 mg/dl. Increased level of Lp(a) is considered to be an
independent risk fa... |
25,943 | [Heart Failure in Patients With Preserved Ejection Fraction - Pumping Heart
Failure?]. | The review analyzes literature data on the phenomenon of chronic heart failure
as a clinical syndrome of hypoperfusion of organs and systems of the body due to
multiple causes of pumping inadequacy of the circulatory system. Special
attention is paid to diastolic heart failure of different origin. Attention is
draw... |
25,944 | [Chronic Heart Failure With Preserved Ejection Fraction: Effective Treatment
Possible?]. | Chronic heart failure with preserved ejection fraction (HFpEF) accounts for
about 50% of cases of heart failure, but pharmacotherapy that improves its
outcomes has not been developed. The proven principle of improving outcomes in
patients with chronic heart failure with a reduced of left ventricular ejection
fracti... |
25,945 | [Aneurysmal Degeneration of a Bioprosthesis]. | We present a clinical case of successful correction of aneurismatic dilatation
of the anastomosis zone after allotransplant implantation. In 2004 this patient
underwent implantation of an arterial allotransplant of "complex architectonics"
because of trauma of the iliofemoral arterial segment. After 12 years he
rep... |
25,946 | Psychosocial Risk Factors in Ambulatory Patients With Arterial Hypertension and
Ischemic Heart Disease of 30 Cities in Russia: Data from the КОМЕТА (Сomet)
Study. | BACKGROUND: Psychosocial (PS) risk factors (RF) make a substantial contribution
in populational burden of cardio-vascular diseases (CVD) and their
complications.
PURPOSE: The KOMETA (Comet) study was directed to obtaining actual information
on PSRF among ambulatory patients with arterial hypertension (AH) and / or
... |
25,947 | Key Drawbacks of Secondary Ischemic Heart Disease Prevention With Drug Therapy:
the Role of Combination Fixed Dose Preparations in Solution of This Problem. | In this article we deal with the problem of low adherence of patients with
ischemic heart disease (IHD) to drug therapy congruent to current
recommendations including patients who underwent invasive interventions aimed at
myocardial revascularization. Based on analysis of literature, we undertake an
attempt to answ... |
25,948 | Ischemic Heart Disease in Subjects of Young Age: Current State of the Problem.
Features of Etiology, Clinical Manifestation and Prognosis. | In addition to conventional risk factors in young patients with ischemic heart
disease (IHD) numerous other risk factors including genetics play an important
role in its causation. Molecular genetic testing is recommended for the
detection of monogenic diseases with a high risk of developing IHD, such as
familial h... |
25,949 | Update of the Diagnostic Criteria of J-Wave Syndrome: New Concepts and Their
Relevance to Cardiology Practice (According to Materials of J-Wave Syndromes
Expert Consensus Conference Report: Emerging Concepts and Gaps in Knowledge
(2016). | This review includes main positions of the revision of diagnostic criteria of
"J-wave syndromes in the J-Wave Syndromes Expert Consensus Conference Report:
Emerging Concepts and Gaps in Knowledge" (2016). The article, systematized
according to the sections of the above-mentioned document, outlines the
questions of ... |
25,950 | Antihypertensive Efficacy of a Triple Fixed-Dose Combination of Perindopril,
Indapamide, and Amlodipine: Clinical Effectiveness in Ambulatory Practice
(Results of the PETRA Study). | Most patients with arterial hypertension (AH) for successful long-term blood
pressure (BP) control require combination of antihypertensive drugs acting on
various target organs. Accumulated experience shows that about 30 % of patients
require combination therapy with 3 drugs from different pharmacological classes.
... |
25,951 | Value of Contrast-Enhanced Echocardiography of Left Cardiac Chambers for
Clinical Practice. | This literature review in devoted to the potential of application of
contrast-enhanced echocardiography (CEE) for assessment of structure and
function of left cardiac chambers. It contains based on current recommendations
discussion of main indications for CEE and analysis of its possibilities in
evaluation of perf... |
25,952 | Myocardial Strain and Stiffness Parameters as a Novel Target of Antihypertensive
Treatment. | In the review, the clinical significance of increased myocardial stiffness and
strain impairment in the settings of arterial hypertension is considered. The
mechanisms of increasing myocardial stiffness as a part of hypertensive heart
disease are presented. Particular attention is paid to the role of the
sympatheti... |
25,953 | Methods of Pharmacological Treatment of Chronic Thromboembolic Pulmonary
Hypertension Current Approaches to the Patients Management. | In this paper we have discussed epidemiology, pathogenesis, and approaches to
treatment of chronic thromboembolic pulmonary hypertension (CTEPH). CTEPH is a
unique potentially curable form of pulmonary hypertension. The gold standard of
CTEPH treatment is pulmonary thromboendarterectomy. However, about 40% of
patie... |
25,954 | Left main coronary artery compression by pulmonary artery aneurism in patients
with long standing pulmonary arterial hypertension. | This review focuses on a rare complication of pulmonary arterial hypertension
(PAH), extravasation compression of the left coronary artery (LCA) dilated by
the pulmonary artery. The review described clinical manifestations and methods
for diagnostics of LCA compression, and advantages of the endovascular
correction... |
25,955 | Left ventricular noncompaction: a distinct cardiomyopathy or a composite
anatomical syndrome? | Left ventricular non-compaction (LVNC) is characterized by hypertrabecularity
(thickened non-compact layer) with deep intertrabecular recesses that are
continuous with the ventricle cavity, and a thin compact layer. The phenotypes
of LVNС are extremely variable: the left or right ventricular variant,
biventricular ... |
25,956 | Daily variability of arterial stiffness of patients with arterial hypertension
depending on the category of cardiovascular risk. | The study of the daily variability of arterial stiffness indicators, depending
on the category of cardiovascular risk. Materials and methods. The study
consistently included patients with essential hypertension who were admitted to
the cardiology department of the Volga district medical center from November 1,
2015... |
25,957 | ST-Elevation Myocardial Infarction in Patients With Malignancies. | Acute myocardial infarction (MI), the most severe complication of coronary
artery disease, develops in 2-4% of patients with various malignancies.
PURPOSE: to explore the specific properties of ST-segment elevation myocardial
infarction (STEMI) course in patients with cancer and its effect on short-term
outcome.
MAT... |
25,958 | Changes of Treatment of Patients With Non-ST Elevation Acute Coronary Syndrome
in Clinical Practice During Recent Several Years (Data From a Series of the
Russian RECORD Registries). | Erlikh A. D. on Behalf of Participants of the RECORD Registers.
PURPOSE: to assess changes in the management of patient with Non-ST Elevation
(NSTE) Acute Coronary Syndrome (ACS) which occurred in Russian hospitals during
recent several years by means of comparing data from a series ofACS registries
RECORD - "old" (... |
25,959 | Independent Predictors of Adverse Cardiovascular Events in Patients With Acute
Coronary Syndrome After Percutaneous Coronary Intervention During
Hospitalization. | PURPOSE: to elucidate independent clinical and laboratory predictors of adverse
cardiovascular events (ACVE) in patients with acute coronary syndrome (ACS)
after percutaneous coronary intervention (PCI) with stenting in early inhospital
period.
MATERIALS AND METHODS: We included in this prospective single center stu... |
25,960 | Bioresorbable Vascular Scaffold Compared With Minimally Invasive Bypass Surgery
for the Left Anterior Descending Coronary Artery Disease: 12-Month Follow up. | THE AIM: Evaluates long-term clinical outcomes of percutaneous coronary
intervention (PCI) with bioresorbable vascular scaffold (BVS) versus minimally
invasive direct coronary artery bypass (MIDCAB) surgery for the treatment of
left anterior descending (LAD) lesions.
METHODS AND RESULTS: In this single-center study ... |
25,961 | Bendopnea: Association With Echocardiographic Features and Clinical Outcomes in
Elderly Patients With Chronic Heart Failure. | AIM: to assess the prevalence of bendopnea and association of this symptom with
clinical, laboratory and echocardiographic features, clinical outcomes during 2
years of follow-up in ambulatory elderly patients with chronic heart failure
(CHF).
MATERIALS AND METHODS: We conducted an open, prospective, non-randomized ... |
25,962 | The Association of Lipoprotein(a), Apolipoprotein(a) Phenotypes and
Autoantibodies to Lipoprotein(a) With Lower Extremity Artery Disease. | AIM: Lipoprotein(a) [Lp(a)] and low molecular weight (LMW) apolipoprotein(a)
[apo(a)] phenotype are risk factors of сoronary heart disease and stroke. Data
about the role of Lp(a) and phenotypes apo(a) in the development of lower
extremity artery disease (LEAD) is scarce. The aim of our study was to assess
the asso... |
25,963 | Implantation of Cardioverter-Defibrillator in Children With Long-QT Syndrome:
Assessment of Indications, Efficacy, and Safety Based on 10-Year Experience. | PURPOSE: to assess specificities of course of the long-QT syndrome in children
before and after implantation of cardioverter-defibrillator (ICD), and
optimization of indications to ICD-therapy.
MATERIALS AND METHODS: We included in this study 48 children with long-QT
syndrome from 44 unrelated families (28 boys and ... |
25,964 | Predictors of Chronic Thromboembolic Pulmonary Hypertension. | PURPOSE: to elucidate predictors of development of chronic thromboembolic
pulmonary hypertension (CTEPH) after acute pulmonary artery thromboembolism
(PTE).
MATERIAL AND METHODS: We included in this study 210 patients hospitalized
with diagnosis of submassive and massive PTE from 2013 to 2017. In 1 to 3 years
after... |
25,965 | Infective Endocarditis in Moscow General Hospital: Clinical Characteristics and
Outcomes (Single-Center 7 Years’ Experience). | AIM: to investigate clinical properties of course and outcomes of infective
endocarditis (IE) depending on source of infection, to find predictors of
mortality in a Moscow general hospital.
MATERIALS AND METHODS: We included in this study 176 patients with definite and
possible infective endocarditis (the Duke crite... |
25,966 | Implantable Cardioverter-Defibrillators are the Main Link in the Modern Concept
of Sudden Cardiac Death Prevention. Problems and Prospects of the Development of
the Method. | The article covers the development of the problem of sudden cardiac death
prevention with the implantable cardioverter-defibrillators from the moment of
creation of these devices to our days. The current concept of primary prevention
of sudden cardiac death, based on the severity of manifestation of heart failure
a... |
25,967 | Noninvasive Assessment of Fractional Flow Reserve Using Mathematical Modeling of
Coronary Flow. | Nowadays an invasive evaluation of fractional flow reserve (FFR) is one of the
main methods used for detecting lesions that cause ischemia. Invasively obtained
FFR <0.75 has the specificity of 100 %, and FFR >0.80 has the sensitivity
>90 %. Recent achievements in computational fluid dynamics and computer
s... |
25,968 | New Tactics for the Treatment of Pulmonary Hypertension: Switching to a More
Effective Therapy. | The article deals with the modern tactics of pulmonary hypertension therapy,
used in case of unsatisfactory clinical response to previous therapy. All
classes of pathogenetic therapy of pulmonary hypertension are presented, as well
as modern views on the risk stratification of annual mortality of patients.
Switchin... |
25,969 | Heart failure with mid-range ejection fraction: are there clinical reasons in
introduction of this new group as a distinct entity? | The article discusses the clinical expedience of isolating into a separate
classification subgroup of patients with heart failure and a mid‑range ejection
fraction (EF) of 40-49 %. Analysis of studies 2017-2018 focusing on the issue of
patients with mid‑range LV EF showed that this subgroup is highly heterogenous
a... |
25,970 | Early diagnosis of cardiotoxic complications of chemotherapy: the possibility of
radiation research methods. | Oncological diseases are the main causes of death in the world. Modern treatment
of cancer patients contributes to an increase in survival rate due to strong
chemotherapeutic drugs, the use of which is accompanied by toxic effects on
cardiomyocytes. The main manifestations of cardiotoxicity are left ventricular
dys... |
25,971 | Characteristics and treatment of patients with heart failure admitted to a
cardiology department in 2002 and 2016. | AIM: To investigate the difference in characteristics of patients admitted to
the Tomsk National Research Medical Center with a diagnosis of heart failure
(HF) in 2002 and 2016.
METHODS: Medical charts of all patients hospitalised in a single centre, with a
diagnosis of HF, were included. Two three‑month periods wer... |
25,972 | Clinical significance of serial biomarkers activity determination after acute
heart failure decompensation: sST2 NT-proBNP role during long-term follow-up. | AIM: Monitoring of concentrations of modern biomarkers to evaluate the efficacy
of long‑term treatment of patients after acute decompensated HF (ADHF).
MATERIALS AND METHODS: The study included 100 patients with severe decompensated
FC II-IV CHF and LV EF <40 % due to IHD, DCMP or AH. At discharge from the
hospit... |
25,973 | High On-Treatment Platelet Reactivity Determinants on Dual Antiplatelet Therapy
in Patients With Ischemic Heart Disease Before Elective Percutaneous Coronary
Intervention. | OBJECTIVE: to determine impact of different laboratory and genetic factors on
high on-treatment platelet reactivity (HOPR) during dual antiplatelet therapy
(DAPT).
METHODS: We included in this study 94 patients with stable ischemic heart
disease (mean age 59±9.67 years). All patients underwent elective PCI with
imp... |
25,974 | Radiofrequency Pulmonary Artery Ablation for Treatment of Residual Pulmonary
Hypertension After Pulmonary Endarterectomy. | OBJECTIVE: to assess the safety and efficiency of radiofrequency pulmonary
artery ablation for treatment of residual pulmonary hypertension after pulmonary
endarterectomy.
MATERIAL AND METHODS: Radiofrequency pulmonary artery denervation (PADN) was
performed in 16 patients (10 men, mean age 39 years [26; 51]). Indic... |
25,975 | Deficit of Magnesium and States of Hypercoagulation: Intellectual Analysis of
Data Obtained From a Sample of Patients Aged 18-50 years From Medical and
Preventive Facilities in Russia. | The states characterized by pronounced hypercoagulable components (deep vein
thrombosis, cardio- and cerebro-vascular pathologies) are caused by multiple
pathophysiological factors, including insufficient supply of magnesium (Mg) and
other micronutrients.
AIM: to present results of analysis of the Institute of Micro... |
25,976 | Contractile Function of Isolated Hearts With Preserved and Reduced Ejection
Fraction In Vivo. | The aim of the study was comparison of contractile function of isolated hearts
of rats with doxorubicin-induced myocardial injury which were tentatively
divided according to the level of ejection fraction determined by
echocardiography in vivo. After 4 weeks of doxorubicin administration (2 mg/kg
subcutaneously onc... |
25,977 | Relationship of Remodeling of Carotid Arteries and Left Ventricular Geometry in
Patients With Chronic Glomerulonephritis. | PURPOSE: to study clinical-functional features of remodeling of carotid arteries
and its relation to restructuring of the left ventricle (LV) in patients with
chronic glomerulonephritis at pre-dialysis stage.
MATERIALS AND METHODS: We examined 269 patients (189 men, 80 women) with chronic
glomerulonephritis (CGN) ag... |
25,978 | Polymorphisms of the SCN10A Gene in Patients With Sick Sinus Syndrome. | PURPOSE: To study association of rs6795970 polymorphism of SCN10A gene with
development of idiopathic sick sinus syndrome (ISSS).
MATERIALS AND METHODS: We examined 109 patients with ISSS, 59 their healthy
1-st-, 2-nd-, and 3-rd-degree relatives, and 630 controls. Patients with ISSS
were divided into subgroups accor... |
25,979 | Chronic Kidney Disease as Basis of High Thrombotic and Bleeding Risk in Patients
With Atrial Fibrillation: Place of Oral Anticoagulants. | Chronic kidney disease (CKD) aggravates course of practically all diseases by
worsening outcomes and hindering adequate treatment. Specificities of renal
excretion of various drugs, changes of parameters of their pharmacokinetics and
pharmacodynamics, nephrotoxic effects of drugs, tactics of drug therapy in
conditi... |
25,980 | NONVALVULAR ATRIAL FIBRILLATION AND DIABETIC NEPHROPATHY: EPIDEMIOLOGY,
PROGNOSIS, AND CHOICE OF ANTICOAGULANT THERAPY. | In this review we present data on prevalence of atrial fibrillation (AF) among
patients with type 2 diabetes (T2D), diabetic nephropathy and chronic kidney
disease (CKD). Patients with nonvalvular AF and T2D combined with CKD have
elevated risk of both bleeding and thromboembolic complications, as well as of
all ca... |
25,981 | The Case of Successful Surgical Treatment of a Patient With Thoracic Endograft
Infection in 5 Years After Thoracic Endovascular Aortic Repair. | We present here a case of successful staged treatment of a patient with
para-aortic abscess that arose 5 years after thoracic endovascular aortic repair
because of thoracic aortic aneurysm. After stabilization of the patient's
condition by intensive antibiotic therapy we performed left-subclavian
extra-thoracic deb... |
25,982 | Possible genetically determined mechanisms of arterial hypertension in tobacco
smoking. | Te increase in the prevalence of arterial hypertension (AH) in populations,
ineffective treatment, the need for risk stratifcation, prevention, early
diagnosis and successful treatment, actualize genomic studies to develop a
personalized therapeutic approach to AH. Te review investigates the possible
genetically det... |
25,983 | Thrombosis risk factors and gene mutations in young age patients with acute
coronary syndrome. | Goal of research. Study the role of thrombosis risk factors and polymorphisms in
genes in young age patients with acute coronary syndrome (ACS).
MATERIALS AND METHODS: Te study included 299 patients of age 25 to 44 years old
with ACS were treated from 2012 to 2017 at the department of myocardial
infarction 1st KGBUZ... |
25,984 | Antihypertensive and vasoprotective effectiveness of the chronopharmacotherapy
in patients with arterial hypertension after acute cerebrovascular accident. | AIM: To evaluate the effectiveness of combined antihypertensive
chronopharmacotherapy and estimate the daily blood pressure profle (BP)
parameters, such as: stiffness of the vascular wall and central aortic pressure
in patients with arterial hypertension (AH) who underwent transient ischemic
atack (TIA) or ischemic s... |
25,985 | EPOCHA-AH 1998–2017. Dynamics of prevalence, awareness of arterial hypertension,
treatment coverage, and effective control of blood pressure in the European part
of the Russian Federation. | AIM: To perform a repeated epidemiological study of a representative sample in
the European part of the Russian Federation in 2017 and to compare the dynamics
of arterial hypertension (AH) prevalence with the effectiveness of blood pressure
(BP) control in the population compared to 1998, 2002, and 2007.
MATERIALS AN... |
25,986 | Atherosclerosis of brachiocephalic arteries and arterial stiffness in patients
with breast cancer. | Cardiovascular toxicity is one of the important problems of clinical oncology.
Atherosclerosis progression was demonstrated in patients with cancer and
chemotherapy.Te aim - to evaluate the vascular wall characteristics and to
determine the predictors of AS of brachiocephalic arteries progression during
anticancer ... |
25,987 | Multimarker Approach in Risk Stratification of Patients with Decompensated Heart
Failure. | PURPOSE: to study prognostic value of various biomarkers and their combinations
in patients who survived decompensation of chronic heart failure.
MATERIALS AND METHODS: Patients (n=159) who were hospitalized with diagnosis of
heart failure (HF) decompensation were included in a prospective single-center
study. Exami... |
25,988 | Impact of Depressive Symptoms on All-Cause Mortality in Patients with Congestive
Heart Failure After Cardiac Resynchronization Therapy. | PURPOSE: to assess the association between depression and all-cause mortality in
patients with congestive heart failure (CHF) after cardiac resynchronization
therapy (CRT).
MATERIALS AND METHODS: We enrolled in this study 156 patients (mean age 55.3±9.6
years) with CHF and implanted devices for CRT. Mean duration of... |
25,989 | Morphofunctional Features of The Diaphragm in Patients With Chronic Heart
Failure. | AIM: to study changes in the volumes of muscle, fat, and connective tissue in
postmortem issue samples (autoptates) from diaphragm, right ventricle, lower
limb (gastrocnemius muscle), as well as morphological changes of the diaphragm
muscular structure in patients with different functional classes of heart
failure ... |
25,990 | Effect of Perindopril / Amlodipine Fixed Combination on Ultrasound
Characteristics of Ventricles of the Heart in Patients with Ischemic Heart
Disease and Arterial Hypertension. | In a group of 32 patients with combined ischemic heart disease (IHD) and
arterial hypertension (AH) we studied dynamics of parameters of blood pressure
and ECG 24-hour monitoring, as well as ultrasound structural and functional
parameters of left and right ventricles during 3-month therapy with fixed dose
combinati... |
25,991 | Difficulties of Diagnostics of Obstructive Coronary Artery Lesions in Patients
with Stable Ischemic Heart Disease and Possibilities of Single-Photon Emission
Computed Tomography. | PURPOSE: to assess diagnostic capabilities of single-photon emission computed
tomography (SPECT) in the detection of obstructive coronary artery (CA) lesions,
depending on the meeting appropriate use criteria.
MATERIALS AND METHODS: We used in this retrospective analysis data from 107
patients with previously diagno... |
25,992 | Adherence to Medical Treatment in Patients who Have Experienced Acute Coronary
Syndrome and Percutaneous Coronary Intervention. | PURPOSE: to study adherence to therapy after percutaneous coronary intervention
(PCI) for acute coronary syndrome (ACS). We analyzed retrospectively 127 case
histories of patients who underwent PCI for ACS in 2015 (in Udmurtia at that
time PCIs were mostly carried out later than 6 hours after onset of symptoms).
INC... |
25,993 | Prevalence of Atrial Fibrillation and use of Oral Antithrombotic Therapy in
Patients with Acute Coronary Syndrome. | PURPOSE: To assess the prevalence of atrial fibrillation (AF) and use of
antithrombotic agents in adult patients with acute coronary syndrome (ACS).
MATERIALS AND METHODS: We consecutively enrolled all ACS patients (n=1155) who
were hospitalized in two Moscowbased percutaneous coronary intervention centers
(each cen... |
25,994 | Gender and Age Characteristics of Mortality From Diseases of the Circulatory
System of the Moscow region. Data 2016 year. | Contribution of diseases of the circulatory system to total mortality of the
population remains high. Therefore it is necessary to study factors with most
substantial impact on regional morbidity and mortality for elaboration of
targeted programs of preventive measures aimed at definite population
groups.Purpose of... |
25,995 | Population Risk of Ischemic Heart Disease Depending on the Volume of Alcohol
Consumption by the Population (ЭССЕ-РФ Study in the Kemerovo Region). | PURPOSE: to assess relationship between the prevalence of cardiovascular risk
factors and associated population risk of ischemic heart disease (IHD) alcohol
consumption in the Siberian region (Kemerovo Region).
MATERIALS AND METHODS: This work was carried out within the framework of a
multicenter epidemiological stu... |
25,996 | Functional Diagnostic Methods in Cardiac Prognosis in Major Abdominal Surgery in
Patients with Heart Disease or Over 65 Years Old. | PURPOSE OF THE STUDY: Evaluation of the value of the results of the use of
cardiac functional examination methods for the stratification of the risk of
developing cardiovascular complications in planned abdominal surgical
interventions in patients over 65 years of age or with cardiac pathology.
MATERIALS AND METHODS... |
25,997 | Rate of Complications at Early Removal of Compression Bandage After Transradial
Coronary Angiography. | PURPOSE: to compare rates of access site complications at early (after 4 hours)
and traditional (after 24 hours) removal of a compression bandage after
diagnostic transradial (TR) coronary angiography (CA) in patients not receiving
anticoagulants.
MATERIALS AND METHODS: We included into this study 392 patients (mean... |
25,998 | Current Trends and Possibilities of Providing Medical Palliative Care in Chronic
Heart Failure. | Chronic heart failure (CHF) is an important healthcare problem because of high
prevalence, morbidity and mortality rates. Treatment resistant symptoms, need
for communication and support, unite patients with CHF and oncological diseases
but despite that CHF patients rarely receive specialized palliative care (SPC). ... |
25,999 | Possibilities and perspectives of using cardiac contractility modulation in
patients with chronic heart failure and atrial fibrillation. | Heart failure is one of the main health care problems all over the world.
Although, there are many drugs with proven effectiveness and hi-tech devices,
there is a continuous process of searching new possibilities in heart failure
prophylaxis going on because of huge economic burden and impact on life quality.
Devel... |
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