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26,100 | [Assessment of the Role of Oxidative Stress Indicators and Early Markers of
Myocardial Injury and Disfunction in Patients with Lymphoproliferative
Diseases]. | PURPOSE: to study dynamics of indicators of oxidative stress and their role in
development of cardiotoxicity in patients with lympho-proliferative diseases at
the background of polychemotherapy.
MATERIALS AND METHODS: We included into this study 30 patients with newly
detected Non-Hodgkin lymphomas. The control grou... |
26,101 | [Participation of Sphingolipids in the Pathogenesis of Atherosclerosis]. | Lipid metabolism disorders are the most significant risk factor of development
of cardiovascular diseases (CVD). In the process of diagnosing ischemic heart
disease and other cardiovascular pathologies, levels of total cholesterol, low-
and high- density lipoprotein cholesterol, triglycerides are determined.
Howeve... |
26,102 | [Myocardial Strain Properties in Patients with Chronic Heart Failure]. | Chronic heart failure is the cause of hospitalization of every fifth
cardiological patient. Number of patients with heart failure symptoms that have
preserved or intermediate left ventricle ejection fraction increases, i.e. grows
portion of diastolic heart failure grows. Gray scale myocardial strain
techniques prov... |
26,103 | [Non-pharmaceutical treatment of dyslipidemia: review of current methods of diet
and nutraceuticals]. | The role of nutrition in the development and progression of atherosclerosis is
well known. The correction of diet in patients with dyslipidemia is important as
an independent intervention (in the group of patients with low and, partially,
moderate cardiovascular risk), and as an addition to drug therapy in patients ... |
26,104 | [Prognostic role of p53 gene polymorphism in risk assessment of
anthracycline-induced cardiotoxicity]. | AIMS: To study the prognostic significance of polymorphism of the p53 gene
(polymorphism Arg72Pro exon 4, rs1042522) on the development of cardiotoxic
remodeling of the left ventricle and heart failure.
MATERIAL AND METHODS: A total of 176 women with breast cancer who received
anthracycline antibiotics as part of po... |
26,105 | [Age characteristics of risk cardiovascular complications in women with left
breast cancer with preserved ejection fraction at the stage of chemotherapy and
radiotherapy]. | AIM: A study of the risk factors for middle-aged and elderly women HER2neu with
negative left breast cancer and a normal ejection fraction at the stage of
chemoradiotherapy in everyday clinical practice. Matherial and methods. 61 women
with left breast cancer without severe cardiovascular pathology were examined at ... |
26,106 | [Study of associations of polymorphism of matrix metalloproteinases genes with
the development of arterial hypertension in men]. | The aim of research. To study the association of polymorphic loci of matrix
metalloproteinases with the development of essential hypertension (EH) in men of
the Central Chernozem Region of Russia. Materials and methods. A study of 564
men with EH and 257 control men was performed. Analysis of the polymorphic loci
o... |
26,107 | [Clinical and prognostic value of the residual activity of platelets in patients
with acute coronary syndrome without st segment elevation]. | AIM: To study clinical prognostic value of residual platelet activity in
patients with acute coronary syndrome without ST segment elevation.
MATERIAL AND METHODS: The study included 120 patients with acute coronary
syndrome without ST segment elevation (NSTE ACS) with coronary artery stenting.
Testing of residual re... |
26,108 | [What new will implementation of European Guidelines for managing arterial
hypertension introduce into real-life clinical practice?]. | AIM: To analyze the effect of introducing new treatment goals in hypertension
stated in the 2018 European Society of Cardiology and European Society of
Hypertension Guidelines on prevalence and treatment efficacy of arterial
hypertension (AH) in a representative sample of patients in the European part of
the Russia... |
26,109 | [Mechanisms of exercise intolerance in patients with heart failure and preserved
ejection fraction. Part II: The role of right heart chambers, vascular system
and skeletal muscles]. | The main clinical manifestation of heart failure with preserved ejection
fraction is poor exercise tolerance. In addi-tion to the dysfunction of the left
heart chambers, which were presented in the first part of this review, many
other disorders are involved in poor exercise tolerance in such patients:
impairments ... |
26,110 | [Chronic obstructive pulmonary disease and cardiovascular comorbidity]. | In recent years, a greater understanding of the heterogeneity and complexity of
chronic obstructive pulmonary disease (COPD) has come from the point of view of
an integrated clinical assessment of severity, pathophysiology, and the
relationship with other pathologies. A typical COPD patient suffers on average 4
or ... |
26,111 | [Reverse remodelling of the heart after atrial fibrillation ablation in patients
with heart failure with reduced ejection fraction]. | AIM: To evaluate the effect of atrial fibrillation (AF) catheter ablation (CA)
on long-term freedom from AF and left heart reverse remodeling in patients with
heart failure with reduced ejection fraction (HFrEF).
METHODS: There were 47 patients (mean age 53.3 ± 10 years, 39 males) enrolled
into single-center observa... |
26,112 | [Prognostic value of acute cardiorenal syndrome in patients with acute cardiac
pathology]. | AIM: To assess the prevalence and prognostic value of AKI in patients with acute
decompensation of chronic heart failure (ADCHF) with a reduced ejection fraction
(HFrEF) and with preserved ejection fraction (HFpEF) or acute coronary syndrome
(ACS), to identify predictors of AKI.
MATERIALS AND METHODS: In a prospecti... |
26,113 | [Characteristic of infectious status in patients with acutely decompencated
chronic heart failure and its impact on annual prognosis]. | AIM: The assessment of infectious status in patients with acutely decompensated
chronic heart faiure (ADCHF) without evident signs of acute inflammatory stress
and its impact on the 1 year prognosis.
MATERIAL AND METHODS: Totally, 65 patients with ADCHF of ischemic origin
investigated, age 67,3±2,3 y.o. All patients... |
26,114 | [Office and 44-hour ambulatory blood pressure and central haemodynamic
parameters in the patients with end-stage renal diseases undergoing
haemodialysis]. | AIM: To assess the incidence of blood pressure (BP) control and various
phenotypes of BP by comparing the results of office and 44-hour ambulatory
brachial and central BP measurement in patients with end-stage renal disease
(ESRD) on program hemodialysis (HD).
MATERIALS AND METHODS: In 68 patients ESRD receiving ren... |
26,115 | [Association of Atrial Fibrillation with Coronary Lesion in Ischemic Heart
Disease Patients]. | AIM: to find out whether atrial fibrillation (AF) in patients with ischemic
heart disease (IHD) is related to some definite localization or extent of
coronary artery lesions or type of coronary circulation.
MATERIALS AND METHODS: We compared data of clinical, laboratory, and
instrumental examination of 178 IHD patie... |
26,116 | [Long-Term Survival of Patients with Ischemic Heart Disease After Surgical
Correction of Moderate Ischemic Mitral Regurgitation]. | AIM: to assess effect of correction of moderate ischemic mitral regurgitation
(IMR) in patients with ischemic cardiomyopathy (IMC) in immediate and remote
period.
MATERIALS AND METHODS: We included in a single center prospective study 76
patients with IMC, left ventricular ejection fraction ≤35 %, and moderate IMR. ... |
26,117 | [Features of Cardiovascular Risk Factors, Target Organ Damage in Patients with
Diabetes Mellitus Type 2 and Arterial Hypertension]. | AIM: to investigate relationship between arterial hypertension (AH) and risk
factors / subclinical damage of target organs in patients with type 2 diabetes
mellitus (DM2).
METHODS: We included into this clinical epidemiological study 528 patients with
DM2 (30.5 % men, 69.5 % women; mean age 54.1±0.3 years; 80.3 % wi... |
26,118 | [The Possibility of Correcting Anxiety Symptoms in Cardiac Patients in Primary
Care Settings: Results of the Therapeutic Part of a Russian Multicenter Study
COMETA]. | PURPOSE: to assess efficacy of correction of anxiety states by anxiolytic drug
fabomotizole in ambulatory patients with arterial hypertension (AH) and / or
ischemic heart disease (IHD).
MATERIALS AND METHODS: In the framework of multicenter cross-sectional study
with participation of patients aged ≥55 years with ver... |
26,119 | [Spontaneous Coronary Artery Dissection]. | During several recent decades spontaneous coronary artery dissection (SCAD) has
been known as one of causes of development of acute coronary syndrome (ACS). It
has been assumed that this condition is extremely rarely met and is associated
with pregnancy and postpartum period. The use in clinical practice of high
se... |
26,120 | [Approaches to the Diagnosis and Treatment of Arterial Hypertension in the Light
of European Recommendations]. | In this review we present analysis the European recommendations on hypertension
- what's new and what has changed in the tactics of managing patients with
arterial hypertension (AH). We compared recommendations on hypertension of the
European Society of Cardiology (ESC) and the European Society of hypertension
(ESH... |
26,121 | [Surgical Treatment of Ischemic Cardiomyopathy: Current State of the Problem]. | In this article we present discussion of the current state of the problem of
surgical treatment of ischemic cardiomyopathy (ICM). The pathophysiological
aspects of left ventricular remodeling in patients with ICM are also covered. A
detailed characterization of methods for assessing the myocardial viability is
give... |
26,122 | [The First in Russia Experience of Successful Implementation of Constant
Neurostimulation of the Spinal Cord in the Complex Treatment of a Patient with
Permanent Form of Atrial Fibrillation Combined with Spinal Stenosis]. | This article describes for the first time in the domestic literature a clinical
case of the therapeutic effect of neuromodulation on the permanent form of
atrial fibrillation and chronic heart failure in an elderly patient with spinal
stenosis which led to the development of pain syndrome and movement disorders.
Fo... |
26,123 | [The Case of Fulminant Myocarditis]. | Fulminant myocarditis (FM) is a severe form of inflammatory myocardial injury
rapidly developing as acute heart failure, cardiogenic shock, or
life-threatening disturbances of cardiac rhythm. FM requires intensive treatment
including drug therapy, mechanical circulatory support, and in some cases -
heart transplant... |
26,124 | [Treatment of Patients with Stable Manifestations of Atherosclerotic Vascular
Disease: New Possibilities (Conclusion of the Council of Experts from November
16, 2018, Rostov-on-Don)]. | In the conclusion of the council of experts (list of participants see text) the
following issues are discussed: regional specifics of diagnostics and therapy of
patients with ischemic heart disease (IHD) and / or peripheral arterial disease
(PAD), methods of risk assessment in patients with stable course of
atheros... |
26,125 | [Relation of Functional Activity of Platelets to Prognosis of Unfavorable
Cardiovascular Events in Patients with Acute Coronary Syndrome. Results of a
Registry Study]. | AIM: to assess relation ofhigh functional activity ofplatelets to prognosis
ofunfavorable cardiovascular events in patients with Acute Coronary Syndrome
(ACS).
MATERIALS: The study was based on the data of a single center ACS registry
conducted in the Central Clinical Hospital of the Presidential Affairs
Department... |
26,126 | [Hemostatic Gene Polymorphisms in Acute Coronary Syndrome with Nonobstructive
Coronary Atherosclerosis]. | PURPOSE: to study distribution of genes of the coagulation system, unfavorable
in relation to the risk of thrombosis, and their influence on serum parameters
ofthe hemostasis system in patients with nonobstructive coronary atherosclerosis
(NCA) and acute coronary syndrome (ACS).
MATERIALS AND METHODS: We included in... |
26,127 | [The Diagnostic Accuracy of Exercise Treadmill Testing and Stress
Echocardiography for the Detection of Obstructive Coronary Artery Disease in
Patients Aged ≥ 70 Years]. | AIM: to compare diagnostic accuracy of exercise treadmill testing and stress
echocardiography in the diagnosis of stable coronary artery disease (CAD) in
patients aged >70 years.
MATERIALS AND METHODS: The study included 390 patients aged >70 years with
suspected stable ischemic heart disease, who underwent el... |
26,128 | [Antihypertensive Effect of Switching to a Fixed Perindopril/Amlodipine
Combination in Patients Ineffectively Treated by Free Sartan-Containing
Combinations. Results of the AVANGARD Study]. | Finding the best options for combined antihypertensive therapy is one of the
main tasks to be solved for achieving target blood pressure (BP) and,
accordingly, reduction of the risk of complications in patients with arterial
hypertension (AH).Purpose of this study was to evaluate the effectiveness of the
perindopri... |
26,129 | [The Relationship of the Concentration of Lipoprotein(a) and Markers of
Inflammation with Multifocal Atherosclerosis in Women]. | PURPOSE: to study relationship of lipoprotein(a) [Lp(a)], indicators of systemic
inflammation and humoral immunity with severity of atherosclerotic involvement
of various vascular beds in women.
MATERIALS AND METHODS: We included in this study 148 women aged 69±11 years with
results of instrumental investigation of ... |
26,130 | [The Use of Selective Inhibitor of If-Channels Ivabradine in Patients with
Ischemic Heart Disease, Heart Failure with High Heart Rate]. | Ischemic heart disease (IHD) and chronic heart failure (CHF) belong to leading
causes of death among patients with cardiovascular diseases (CVD). Modern
medical approaches to the treatment of patients with CHF do not always provide a
significant improvement in the quality of life, a decrease in the frequency of
CHF... |
26,131 | [Cognitive Dysfunction at the Background of Atrial Fibrillation:
Clinical-Pathological Aspects, Diagnostics and Prevention, Issues of the Use of
the Application of Anticoagulant Therapy]. | Atrial fibrillation (AF) and cognitive dysfunction - common states with similar
risk factors. Recently significant scientific epidemiological data has been
received in favor of independence of effect of AF on possibility of development
of cognitive dysfunction. In this review we present problems of prevalence,
path... |
26,132 | [The Role of microRNA in the Development of Ischemic Heart Disease]. | Coronary artery disease is the most clinically significant manifestation of
atherosclerosis and the main cause of morbidity and mortality around the world.
Atherogenesis is a complex process, involving various types of cells and
regulatory molecules. MicroRNA molecules were discovered at the end of the 20th
century... |
26,133 | [The Main Provisions of the International Recommendations on Detection of
Endocrine Hypertension]. | In 2017 the Endocrine Society issued the Scientific Statement "Screening for
Endocrine Hypertension" This document was developed by experts from different
medical institutions of USA, Europe and Australia. Herein we present the main
provisions of this Statement in the form of brief algorithm for the clinicians'
act... |
26,134 | [Telemonitoring in patients with chronic heart failure]. | Actuality. High risk of hospitalisation and death in patients with heart failure
highlight the importance of developing methods to moni‑ tor weight, diuresis,
heart rate and other parameters and provide the physicians with an ability to
change the therapy immediately if needed. The aim of this work is an analysis of... |
26,135 | [Left ventricle myocardium hypertrophy of donor heart: the results and outlook]. | Left ventricular hypertrophy - is one of the most frequent structural changes in
the heart. This article is devoted to the assessment of modern views on the
causes of myocardial hypertrophy of the donor heart, indications and
contraindications for the heart trans‑ plantation, the outlook of expanding the
pool of ef... |
26,136 | [Efficiency of pharmacogenetic approach to anticoagulant therapy in patients
with prosthetic heart valves]. | BACKGROUND: This study examined clinical, demographic, anthropometric, and
inheritance factors that influence individual sensitivity to warfarin therapy
after heart valve surgery. The clinical significance of the pharmacogenetic
approach was assessed using the individual time frame and time spent in the INR
therape... |
26,137 | [Medical awareness of risk factors of cardiovascular diseases in different types
of hospitalized patients (part 2)]. | OBJECTIVE: To study medical awareness of cardiovascular risk factors (RFs) in
different types of hospitalized patients (pts).
METHODS: A total of 150 pts from neurological, endocrinological and cardiac
units one of Moscow city hospital were enrolled into the survey (50 pts in each
unit). The pts were interviewed dur... |
26,138 | [Therapy of patients with the high risk of arterial hypertension with the use of
telmisartan]. | AIM: The study assesses the effects of therapy based on the use of telmisartan
in patients with arterial hypertension and stable angina on the clinical and
functional indicators of the cardiovascularvascular system.
MATERIAL AND METHODS: 52 patients with a combination of arterial hypertension
(AH) I and II stages an... |
26,139 | [Clinical observation of the successful outcome of balloon angioplasty of the
right coronary artery of the heart fourteen years after the procedure in a
patient with chronic ischemic heart disease]. | The method of isolated angioplasty has long ceased to be the leading
interventional method of treating ischemic heart disease. This clinical case
study describes an example of a good fourteen-year result of balloon angioplasty
in a patient with stable angina pectoris. A specific example demonstrates the
excellent s... |
26,140 | Structural and Functional Properties of the Left Atrium in Healthy Volunteers
and Patients With Atrial Fibrillation: Data of Magnetic Resonance Imaging. | BACKGROUND: In the recent years, there has been an increasing number of
publications postulating that data on left atrial (LA) structure obtained by
late gadolinium enhancement magnetic resonance imaging (LGE MRI) can improve the
management of patients with atrial fibrillation (AF). At the same time, similar
data r... |
26,141 | Effect of Type 2 Diabetes Mellitus on Five-Year Survival of Patients
Hospitalized Because of Acute Decompensated Heart Failure. | OBJECTIVE: To assess the impact of type 2 diabetes mellitus (T2DM) on prognosis
of patients hospitalized because of acute decompensated heart failure (ADHF).
MATERIALS AND METHODS: We analyzed data of the hospital register of ADHF which
comprised information on 735 patients (254 [35%] with T2DM) consecutively
admitt... |
26,142 | Head to Head Comparison of Suppression of Tumorogenicity 2 and Copeptin
Significance for Prognosis of Patients After Acute Heart Failure Decompensation. | PURPOSE: To assess the suppression of tumorogenicity 2 (ST2) and copeptin
significance for risk stratification of patient (pts) with acute decompensated
heart failure (ADHF) during long-term follow-up compared with traditional risk
factors.
METHODS: We included in a prospective study 159 pts with ADHF. Blood samples... |
26,143 | Effects of High-Dose Statin Therapy on Cognitive Functions and Quality of Life
in Very High Cardiovascular Risk Patients. | AIM: To investigate the effects of intensive lipid-lowering therapy on cognitive
functions and quality of life in patients (pts) with very high cardiovascular
risk.
MATERIAL AND METHODS: In 93 pts (58 men, 63.2±9.5 years old with history of
clinically evident cardiovascular disease and fasting low-density lipoprotei... |
26,144 | Randomized Comparison of Two Approaches to Initial Warfarin Dosing: Time in
Therapeutic Range of International Normalized Ratio During Hospitalization. | AIM: To perform a randomized, open-label comparison of average time in
therapeutic range (TTR) of international normalized ratio (INR) using two
approaches to initial warfarin dosing during hospitalization: the standard
method and the one using individual patient characteristics (clinical algorithm
- the studied ap... |
26,145 | Current Echocardiographic Techniques for Evaluation of the Right Ventricle. | The review is dedicated to the new echocardiographic techniques in the
assessment of right ventricular (RV) function, such as twodimensional speckle
tracking and determining the RV volume by a three-dimensional model. Subclinical
changes in RV function are of great importance for the diagnosis and assessment
of pro... |
26,146 | Lizinopril in the Treatment of Arterial Hypertension. | Despite availability of a wide selection of antihypertensive drugs, only a small
portion of patients with arterial hypertension are treated effectively.
Angiotensin converting enzyme inhibitors (ACEI) are considered drugs of first
choice for starting therapy of uncomplicated arterial hypertension. Among large
numbe... |
26,147 | [Multifactorial Prognostication of the Development of Stent Thrombosis in
Patients with Acute Coronary Syndrome after Percutaneous Coronary Intervention
on the background of Dual Antiplatelet Therapy]. | AIM: to identify predictors of stent thrombosis in patients with acute coronary
syndrome (ACS) after percutaneous coronary intervention (PCI) for 12 months by
creating a miathematical logistic regression model to optimize rehabilitation,
secondary prevention of ischemic events in the first year after ACS, as well as... |
26,148 | [Acute Coronary Syndrome Registry of High Risk Patients: 30-Day Outcome]. | AIM: The aim of the study is to evaluate important additional cardiovascular
(CV) risk factors of major adverse cardiac events (MACE) in patients with acute
coronary syndrome (ACS) during the first 30 days after index event.
MATERIALS AND METHODS: Overall 750 patients with ACS were enrolled in the single
center pros... |
26,149 | [The efficacy of secondary prevention programs with remote support in coronary
heart disease patients with abdominal obesity]. | Background Long-term secondary preventive programs in coronary heart disease
(CHD) are of highest efficacy but numerous logistical problems often compromise
their implementation. Contemporary remote technologies have a potential to
overcome these barriers.
AIM: To assess the impact of 2 preventive counselling progr... |
26,150 | [Features of changes in volume-impedance hemodynamic indicators during the tilt
test in young males with a history of vasovagal syncopes]. | BACKGROUND: The direction of changes in hemodynamic parameters during the tilt
test (TT) nin individuals with history of vasovagal syncope (VVS) is a subject
of discussion.
OBJECTIVE: to study changes of volume-impedance hemodynamic indicators in the
process of tilt test in somatically healthy young men with history... |
26,151 | [Echocardiographic Stress Test with Adenosine Triphosphate: Optimization of the
Algorithm]. | PURPOSE: To: 1) optimize algorithm of stress echocardiography (s-Echo) with
intravenous adenosine triphosphate (ATP) infusion taking into account
pharmacokinetics and pharmacodynamics of ATP in human body, 2) test new
algorithm in patients with coronary and other heart diseases.
MATERIALS AND METHODS: In order to de... |
26,152 | [New Algorithms for Evaluation Myocardial Function According to
Echocardiography]. | The article is devoted to the novel methodological approach to assessment of
function of the myocardium and the left ventricle as a whole with the help of
modern methods of processing ultrasound images obtained by echocardiography. It
contains presentation of theoretical prerequisites for elaboration of a new
direc... |
26,153 | [Clinical and Diagnostic Value of Cardiac Markers in Human Biological Fluids]. | The article is devoted to problems of clinical-diagnostic value of determination
of cardio-specific troponins in human biological fluids. Improvement of
laboratory instrumentation and emergence of high sensitivity methods of analysis
have allowed to identify troponins in urine, dialysate, and oral fluid. In the
rev... |
26,154 | [How to maintain an adherence to oral anticoagulant in a patient with atrial
fibrillation?]. | Less onerous, compared with warfarin, treatment with direct oral anticoagulants
(DOA) can lead to better adherence to treatment of patients with atrial
fibrillation (AF). However, in a certain number of patients with AF, who were
recommended by DOA, cardioembolic stroke recurs, which is largely due to the
patients'... |
26,155 | [External validation of the ORACLE bleeding risk score using the database of the
RECORD 3 registry]. | AIM: To validate a domestic scale for assessment risk of bleeding ORACUL
(ОРАКУЛ) based on an independent sample of patients with acute coronary syndrome
(ACS).
MATERIALS AND METHODS: External validation of the ORACUL score was carried out
using database of an independent observational study RECORD-3 which comprised... |
26,156 | [The Impact of Secondary Prevention Programs Incorporating Remote Technologies
on Psychological Well-Being and Quality of Life in Coronary Heart Disease
Patients with Abdominal Obesity]. | BACKGROUND: Quality of life, which is determined both by the physical symptoms
and by psychosocial risk factors, is among the primary treatment goals in
coronary heart disease (CHD). Therefore, it is reasonable to assess the impact
of any therapeutic interventions in CHD on these measures.
AIM: To assess the changes... |
26,157 | [The Importance of the Type of Heart Circulation for the Prognosis of Pulmonary
Embolism]. | AIM: To study the distribution of the type of heart circulation (left- dominant,
right- dominant, and mixed (balanced) in patients with pulmonary thromboembolism
of fatal and non-fatal outcome.
MATERIALS AND METHODS: More than 36,000 case histories, protocols and findings
of post-mortem examinations of patients hosp... |
26,158 | [The Diagnostic Accuracy of Сoronary Сomputed Tomography Angiography in the
Diagnosis of Stable Coronary Artery Disease in Patients Aged 70 Years and
Older]. | AIM: The purpose of this study was to evaluate the diagnostic accuracy of
сoronary сomputed tomography angiography (CCTA) in the diagnosis of stable
coronary artery disease (CAD) in patients aged ≥70 years.
MATERIALS AND METHODS: The study included 390 patients aged ≥70 years with
symptoms suggested stable CAD which... |
26,159 | [Lipoprotein(а) Level, Apolipoprotein(а) Polymorphism аnd Autoаntibodies Against
Lipoprotein(а) in Patients with Stenotic Cаrotid Atherosclerosis]. | Аim. Comparative assessment of respiratory indicators according to
multifunctional monitoring (PFM) with the recommended standard for a complete
polysomnographic study and an assessment of the effect of blood pressure (BP)
measurements in PFM on sleep quality. Triаls on the аssociаtion of Lp(а) and
cаrotid аtherosc... |
26,160 | [Why Myocardial Relaxation Always Slows at Cardiac Pathology?]. | Chronic heart failure (CHF) in most cases is due to a decrease in myocardial
contractility. In particular, this results in a reduction in the maximum rate of
the pressure development in the left ventricle. At the same time the maximal
rate of pressure fall at relaxation is also reduced. This is not surprising,
sinc... |
26,161 | [Uncontrolled Arterial Hypertension: Kidney, Neurohormonal Imbalance, and
Approaches to Antihypertensive Drug Therapy]. | Resistant and refractory arterial hypertensions are two distinct clinical
phenotypes of uncontrolled arterial hypertension (AH), which differ in their
sensitivity to antihypertensive drug therapy. The review presents data obtained
in clinical studies devoted to elucidating the involvement of disorders of
neurohormo... |
26,162 | [Atrial Fibrillation in Patients on Dialysis Therapy: Epidemiology, Prognosis
and Choice of Anticoagulant Therapy]. | The review presents data on the prevalence of atrial fibrillation in patients on
dialysis therapy. It is shown that dialysis-dependent patients with non-valve
atrial fibrillation prognosis is extremely unfavorable, significantly increased
risk of death due to both ischemic and hemorrhagic complications. Scales to
a... |
26,163 | [Case of a Сombination of Lupus Erythematosus, Antiphospholipid Syndrome and
Myocardial Infarction]. | Systemic lupus erythematosus (SLE) is a systemic autoimmune disease of unknown
etiology characterized by a wide range of clinical manifestations with damage to
various organs and systems of the body. There are bad prognostic factors for
SLE: damage to the heart, kidney, central nervous system, the development of
he... |
26,164 | [Evaluation of diagnostic criteria of heart failure in patients with atrial
fibrillation and chronic obstructive pulmonary disease]. | AIM: Assess the diagnostic significance of markers of heart failure, to identify
the features of clinical symptoms and structural and functional remodeling of
the left and right heart in patients with chronic heart failure (CHF) in
combination with atrial fibrillation (AF) and chronic obstructive pulmonary
disease ... |
26,165 | [The prognosis of patients with chronic heart failure, depending on adherence to
observation in a specialized heart failure treatment center]. | Actuality. The risk of death of patients with chronic heart failure (CHF) after
acute decompensation of heart failure (ADHF) is directly related to the quality
of the treatment of CHF after discharge from the hospital. In order to achieve
the maximum effect of therapy in patients with CHF, experts in Europe and the ... |
26,166 | [Possibilities and limitations of three-dimensional transesophageal
echocardiography in the diagnosis of thoracic aorta atherosclerosis]. | To compare the possibilities and limitations of the two-dimensional (2D) and
three-dimensional (3D) multiplane transesophageal echocardiography (TEE) for the
diagnosis of the thoracic aorta (TA) atherosclerosis stage, qualitative and
quantitative assessment of aortic atheromas and coronary atherosclerosis
predictio... |
26,167 | [The effectiveness of preventive counseling with the use of remote technologies
on medical awareness of cardiovascular risk factors in patients with high and
very high cardiovascular risk]. | Purpos. To assess the effectiveness of preventive counseling with focus on diet
modification followed by remote support via telephone on awareness of
cardiovascular (CV) risk factors (RFs) in patients (pts) with high/very high CV
risk. Material and methods. This is a prospective randomized controlled study of
100 p... |
26,168 | [Clinical and laboratory features of primary acute myocardial infarction in
patients with obstructive and non-obstructive coronary atherosclerosis]. | According to the literature, 40-60% of patients with acute myocardial infarction
(AMI) have obstructive multivessel coronary artery disease (CA) and 8.8% of
patients have non-obstructive CA lesions. And it is around these two groups of
patients that there are active discussions and disputes regarding the choice of
... |
26,169 | [Evaluation of the antianginal effectiveness of trimetazidine in a new dosage
form for a single dose, depending on the region of the Russian Federation. ODA
trial results]. | The goal evaluation of the effectiveness of treatment with the new TMZ OD dosage
form in different regions of the Russian Federation and regional differences in
the clinical characteristics of patients with coronary artery disease included
in the observation, the nature of their therapy, the presence and degree of
... |
26,170 | [The effect of angiotensin receptors and neprilysin inhibitors on myocardial
remodeling in patients with chronic heart failure and atrial fibrillation]. | AIM: To evaluate the effect of angiotensin-neprilysin receptor inhibitors on
myocardial remodeling in patients with chronic heart failure and atrial
fibrillation.
MATERIALS AND METHODS: We studied dynamics of the parameters of ultrasound
structural and functional parameters of the left atrium and left ventricle of
... |
26,171 | [The renin-angiotensin-aldosterone system as a potential target for therapy in
patients with calcific aortic stenosis: a literature review]. | Calcific aortic valve stenosis (CAVS) is a serious socio-economic problem in
developed countries because this disease is the most common indication for
aortic valve replacement. Currently, there are no methods for non-invasive
treatment of CAVS. Nevertheless, it is assumed that effective drug therapy for
CAVS can b... |
26,172 | [Soluble ST2 - biomarker for prognosis and monitoring in decompensated heart
failure]. | The review aims to appraise the value of determining the concentrations of the
new biomarker sST2 for assessing prognosis and monitoring treatment
effectiveness of patients with decompensated heart failure during an episode of
decompensation and during long-term follow-up after discharge from the hospital.
The arti... |
26,173 | [Anticoagulant activity of direct factor Xa inhibitors as a tool to ensure the
effectiveness and safety of drugs intake]. | The thematic review presents modern solutions using oral anticoagulants with a
focus on direct coagulation factor X inhibitors. It contains information about
the pharmacodynamics and pharmacokinetics of apixaban and rivaroxaban against
the background of different drug intake regimens - twice and once per day. There ... |
26,174 | [Сhanges in quality of life in patients with congestive heart failure after
cardiac resynchronization therapy]. | PURPOSE: To assess the quality of life (QoL) changes in patients with congestive
heart failure (CHF) one year after cardiac resynchronization therapy (CRT).
METHODS: The study included 82 patients (68 males and 14 females) aged from 30
to 74 (mean age 55.8±9.2 years) who underwent implantation of a biventricular
car... |
26,175 | [Impact of hypertension, overweight, hypertriglyceridemia and their combination
for mortality rate according to the results of a 27-year cohort prospective
study]. | To study influence of hypertension, overweight, hypertriglyceridemia and their
combinations for all-cause and cardiovascular mortality risk
formation. Methods. The prevalence of hypertension, overweight and
hypertriglyceridemia was studied (1988-1991) by 27-year prospective cohort study
of unorganized population o... |
26,176 | [An exploration of potential approaches to improve the diagnosis of subclinical
atherosclerosis in patients with high cardiovascular risk]. | PURPOSE: The search for optimal approaches to the diagnosis of subclinical
atherosclerosis using a wide range of traditional and psychosocial risk factors
(RFs), as well as clinical and instrumental diagnostic methods in patients (pts)
with high or very high cardiovascular (CV) risk.
METHODS: This cross-sectional st... |
26,177 | [Association of polyunsaturated fatty acids treatment with coronary mortality. A
meta-analysis]. | AIM: A meta-analysis was undertaken to sum up data on long-chain polyunsaturated
fatty acids treatment and coronary deaths.
METHODS: Only studies with no less than 500 participants and length of follow-up
no less than one year were included. Total number of studies was 13 with 127455
participants.
RESULTS: Fixed fac... |
26,178 | [The prognostic value of the method for determining the estimated glomerular
filtration rate in chronic heart failure with a preserved left ventricular
ejection fraction: focus on cystatin C]. | The aim of the present study is to determine the prognostic value of GFR
reduction according to the CKD-EPI formula, taking into account blood creatinine
and a formula that simultaneously takes into account creatinine and cystatin C
in patients who were hospitalized for the first time due to decompensation of
chron... |
26,179 | [Tactical approaches to the treatment of arterial hypertension in the European
part of the Russian Federation. EPOHA study 2017]. | AIM: Analysis of antihypertensive treatment among different groups of patients
with arterial hypertension from "EPOCHA" study 2017.
MATERIALS AND METHODS: EPOCHA study is a representative sample of the European
part of the Russian Federation was created in 2002 and re-examined in 2017.
RESULTS: 34.6% of the effective... |
26,180 | [Type D personality in patients with coronary heart disease underwent coronary
stenting: a prospective study]. | To evaluate the type D personality relation with clinical and instrumental
parameters in patients with coronary heart disease (CHD) underwent coronary
stenting (CS) and to determine the influence of the personality type D on the
prognosis in these patients within one year after CS. Material and methods. Into
prospe... |
26,181 | [Polymorbidity and its association with the unfavorable course of chronic heart
failure in outpatients aged 60 years and older]. | This study was carried out to evaluate polymorbidity taking into account
geriatric syndromes and their relationship with the course of chronic heart
failure (CHF) in outpatients aged 60 years and older. Methods. We conducted an
open, prospective, non-randomized study. The main group included 80 patients
with CHF, t... |
26,182 | [Difficulties in diagnosis of heart failure with preserved ejection fraction in
clinical practice: dissonance between echocardiography, NTproBNP and H2HFPEF
score]. | This pilot study was aimed to assess the percentage of patients admitted to a
Russian hospital and diagnosed with heart failure with preserved ejection
fraction (HFpEF) maintaining this diagnosis when evaluated against the ESC 2016
and Russian 2017 heart failure guidelines. In addition, we reviewed the
probability ... |
26,183 | [Risk assessment of acute kidney injury in patients with acute cardiovascular
disease without invasive intervention]. | OBJECTIVE: To evaluate the prevalence, predictors, prognostic value of
cardiorenal interrelations in patients with acute cardiovascular disease (CVD),
and to develop an algorithm for stratification these patients at risk of acute
kidney injury (AKI).
MATERIALS AND METHODS: 566 patients (pts) were examined: 278 with ... |
26,184 | [Experience of general surgical procedures in patients after heart
transplantation]. | PURPOSE: To study the frequency of general surgical diseases development snd
their features in patients after heart transplantation (HTx).
METHODS: From January 2010 to December 2018 it was performed 112 HTx (mean age -
46.7±14.0 years old; 82 - male, 30 - female). During 30 days after HTx 9
patients died. After dis... |
26,185 | [Demons-Meigs syndrome or cardiomyopathy: a difficult case of a differential
diagnosis]. | The article presents an overview of the data related to Demons-Meigs syndrome
and the clinical situation associated with a complex differential diagnosis
between myocarditis with the formation of secondary cardiomyopathy and
Demons-Meigs syndrome. A variety of clinical symptom complexes that are
associated with Dem... |
26,186 | [Vasoprotective Effects of Prolonged Therapy With Perindopril A in Patients with
Hypertension Including Concomitant Type 2 Diabetes Mellitus]. | Objective Investigate the dynamics of morphological and functional markers of
vascular remodeling in patients with arterial hypertension (AH), including those
with concomitant type 2 diabetes mellitus (DM2), during 12-month administration
of perindopril A.Material and Methods The study included patients with grade
... |
26,187 | [Multifunctional Monitoring: is it Possible to Simultaneously Evaluate Blood
Pressure and Sleep-Disordered Breathing?]. | Objective Carry out a comparative assessment of respiratory performance, based
on multifunctional monitoring (MFM) and the recommended practice for complete
polysomnography (PSG), and evaluate the effect of the blood pressure (BP)
measurements in MFM on the quality of sleep.Materials and Methods At the first
stage,... |
26,188 | [The Prognostic Role of Biomarkers in Patients With Chronic Heart Failure]. | Objective Investigate the role of biomarkers in the prognosis of the clinical
course of the disease in patients with chronic heart failure (CHF) of different
NYHA functional classes (FC).Material and Methods The study included 132
patients with CHF: Group 1 was composed of 70 patients with NYHA FC II CHF, and
Group... |
26,189 | [Model of Two-Years Forecasting of the Anti-Existent Patients With Acute
Decompensation of Heart Failure on the Background of the Intermediate Fraction
of Left Ventricle]. | OBJECTIVE: Build a prognostic model using clinical, laboratory, and instrumental
data to predict mortality in patients with midrange left ventricular ejection
fraction (mrLVEF) within two years after hospitalization for acute decompensated
heart failure (ADHF).
MATERIALS AND METHODS: The study included 121 patients ... |
26,190 | [On the Causes of Angina Pectoris in Patients With Pulmonary Embolism]. | Objective Compare the distance between the pulmonary artery (PA) and the left
coronary artery (LCA) using pulmonary angiography and the rate of detection of
the signs of left ventricular myocardial ischemiain the first electrocardiogram
(ECG) in pulmonary embolism (PE) patients with or without angina to detect
poss... |
26,191 | [Circular Sympathetic Pulmonary Artery Denervation in Cardiac Surgery Patients
With Mitral Valve Defect, Atrial Fibrillation and High Pulmonary Hypertension]. | Objective Investigate the influence of the sympathetic denervation of the
pulmonary trunk and the orifices of the pulmonary arteries on the degree of
pulmonary hypertension (PH) and outcomes of the surgical treatment of atrial
fibrillation (AF) in patients with mitral valve defects, complicated AF, and
high PH.Mate... |
26,192 | [Risk of Coronary Events in Atrial Fibrillation]. | It has been established that cardiovascular events due to coronary heart disease
are highly prevalent in the population of patients with atrial fibrillation. In
this review, pathophysiologic mechanisms explaining this association are
detailed along with supporting epidemiological evidence. Various methods for the
p... |
26,193 | [Myocardial Infarction in the Group of Patients With Atrial Fibrillation]. | Prevalence of patients with myocardial infarction (MI) and atrial fibrillation
(AF) has been growing every year. These patients represent a highest risk group
and, thus, require special attention of clinicians. The article foсused on
mechanisms of the AF and MI interaction, special aspects of prediction depending
o... |
26,194 | [Pharmacoinvasive Approach to the Treatment of Acute ST-Segment Elevation
Myocardial Infarction. Current State of the Problem]. | The articled focused on the pharmacoinvasive approach to the treatment of acute
ST-segment elevation myocardial infarction. Current guidelines prioritize the
primary transcutaneous coronary intervention. However, in both the Russian
Federation and other countries, there are some peculiarities (logistic issues,
spec... |
26,195 | [Atrial Flutter: up-to-date Problem Evaluation with Clinical Positions]. | The review provides current ideas about the etiology and prevalence of atrial
flutter (AF), mechanism and substrate of arrhythmogenesis, and principles of
clinical and electrophysiological classification of this arrhythmia. Methods for
conservative and surgical treatments of AF, including their comparative aspect,
... |
26,196 | [Lung Ultrasound: new Opportunities for a Cardiologist]. | This review focused on ultrasound examination of lungs, a useful complement to
transthoracic echocardiography (EchoCG), which is superior to chest X-ray in the
diagnostic value. The lung acoustic window always remains open and allows
obtaining high-quality images in most cases. For a cardiologist, the major
points ... |
26,197 | [Lifestyle Modification as a Method of Treatment of Vasovagal Syncope]. | Vasovagal syncope is the most common cause for loss of consciousness. The need
for treatment of this condition is warranted by impaired quality of life and a
risk of trauma due to the fall. At present, there are no medications with proven
preventive effectiveness for vasovagal syncope as demonstrated by large
rando... |
26,198 | [Early changes of energy metabolism, isoformic content and level of titin
phosphorylation at diastolic dysfunction]. | RELEVANCE: Diastolic dysfunction occurring at hypertension, obesity, diabetes,
or treatment with doxorubicin tends to prevail in all patterns of chronic heart
failure. Lack of effective therapy forces to look more into the metabolic
processes in cardiomyocytes.
OBJECTIVE: Assess energy metabolism in cardiomyocytes... |
26,199 | [The Incidence and Possible Predictors of Coronary Restenosis]. | OBJECTIVE: Assess time and possible predictors of restenosis after the
implantation of first- and second-generation coronary stents and bare metal
stents (BMSs) in patients with stable coronary artery disease after elective
coronary stenting.
MATERIALS AND METHODS: From 2010 to 2014, 3,732 (2,897 males, 60 [53; 68] ... |
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