Unnamed: 0 int64 0 2.34M | titles stringlengths 5 21.5M | abst stringlengths 1 21.5M |
|---|---|---|
26,300 | [QT Interval in Patients With COVID-19]. | Since the first case recorded in the end of 2019, the virus SARS-CоV-2 and the
related lung disease COVID-19 have spread over the world and became a threat for
public health. The drugs used for treatment of this disease (azithromycin and
hydroxychloroquine) can prolong the QT interval on the electrocardiogram to
in... |
26,301 | [Features of the clinical picture and outcomes in patients from a heart
transplantation waiting list with different causes of heart failure]. | Aim To identify clinical differences between patients on the heart transplant
waiting list (HTWL) in the origin of chronic heart failure (CHF).Materials and
methods From January 2010 through September 2019, 235 patients (age, 47+13 years
(from 10 to 67 years); men, 79% (n=186)) were included in the HTWL. The patient... |
26,302 | Right Ventricular Longitudinal Strain in Acute Pulmonary Embolism and Right
Ventricular Myocardial Infarction in Patients with McConnell's Sign. | Aim To study the right ventricular (RV) myocardial longitudinal systolic
strain in patient with RV myocardial infarction (MI), and pulmonary embolism
(PE) with and without McConnell' phenomenon.Material and methods This study
included 53 patients with PE (mean age, 59.0±15.1 years; men, 58.5 %) and 30
patient... |
26,303 | [Dynamics of the clinical functional and hemodynamic profile of patients with
pulmonary arterial hypertension with initial monotherapy with endothelin
receptor antagonists: bosentan vs. macitentan]. | Aim To compare results of 24-h treatments with bosentan and macitentan by the
clinical functional status and indexes of pulmonary hemodynamics in patients
with pulmonary arterial hypertension (PAH).Materials and methods Based on the
Russian National Registry (NCT03707561), 44 patients older than 18 years with
PAH (... |
26,304 | [The changes of left ventricular longitudinal systolic function depending on
hypertension and its control: analysis in a population]. | Aim To evaluate changes in left ventricular (LV) systolic function by LV
myocardial global longitudinal strain (GLS) and global strain rate (GSR) in
patients with arterial hypertension (AH) and based on the effectiveness of blood
pressure (BP) control in a Russian population sample of individuals older than
55 year... |
26,305 | [Diagnostic and Prognostic Markers of Chronic Heart Failure in Patients with
Occupational Chronic Obstructive Pulmonary Disease]. | Aim Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are
a common comorbidity. Professional chronic obstructive pulmonary disease (PCOPD)
is a specific phenotype, which suggests peculiarities in the development of HF.
Difficulties of HF diagnosis in such patients determine the relevance of
s... |
26,306 | [Efficacy and safety of new oral anticoagulants as part of triple antithrombotic
therapy in patients with atrial fibrillation and acute coronary syndrome. Data
from an observational study]. | Aim To study efficacy and safety of a triple antithrombotic therapy with direct
oral anticoagulants (DOAC) versus warfarin in patients with atrial fibrillation
after acute coronary syndrome, for 12 months following discharge from the
hospital.Materials and methods This single-site cohort, prospective,
observational... |
26,307 | [The prognostic value of high-sensitivity C-reactive protein blood level after
coronary stenting for the development of stent restenosis]. | Aim To analyze the relationship between serum concentrations of
high-sensitivity C-reactive protein (hsCRP) in dynamics and development of
restenosis at 12 months following elective coronary stent placement
(CSP).Material and methods The key role in atherogenesis, neointimal
proliferation and restenosis belon... |
26,308 | [Association of left bundle branch block definitions with response to cardiac
resynchronisation therapy in patients with congestive heart failure]. | Aim To compare diagnostic significance of different criteria for complete left
bundle branch block (cLBBB) in prediction of reverse left ventricular (LV)
remodeling associated with cardiac resynchronization therapy (CRT).Materials and
methods This study included 93 patients (men, 81.7 %; mean age at the time of
imp... |
26,309 | Safety of low-dose prolonged infusion of tissue plasminogen activator therapy in
patients with thromboembolic events in the intensive care unit. | Objective Thromboembolic events such as acute coronary syndrome related
prosthetic heart valve thrombosis, pulmonary artery embolism and renal artery
embolism are a rare condition but a major cause of morbidity and mortality. In
this study we discussed low-dose thrombolytic therapy, in patients with
thromboembolic ... |
26,310 | Results of Minimally Invasive Valve-Sparing Aortic Root Valve Surgery:
Propensity Score Matching Analysis. | Aim Evaluation of efficacy and safety of minimally invasive, valve-sparing
interventions on the aortic root and a comparative analysis of outcomes versus a
group of patients with a complete sternotomy intervention using the method of
propensity score matching (PSM).Materials and methods From 2016 through 2019, ... |
26,311 | [Prevention of Diastolic Dysfunction Caused by Doxorubicin by Mitochondrial
Antioxidant Plastomitin]. | Aim An attempt to prevent the development of diastolic dysfunction (DD)
with the mitochondrial antioxidant plastomitin on a model of doxorubicin-induced
cardiomyopathy. DD is a type of chronic heart failure. Due to the increasing
number of patients with this condition and the absence of effective therapy,
deve... |
26,312 | [Atrial Fibrillation and Diabetes Mellitus: the Control of Thromboembolic Risk]. | Atrial fibrillation is one of the most common concomitant diseases in patients
with diabetes mellitus (DM). Meta-analyses of multiple studies have shown that
the risk of AF is higher for diabetic patients with impaired glucose homeostasis
than for patients without DM. Patients with AF and DM were younger, more
freq... |
26,313 | [The balance of benefit and risk in prescribing antithrombotic therapy for
patients with coronary artery disease. How to deal with the gastrointestinal
bleeding problem?]. | The review focuses on upper gastrointestinal (GI) bleeding in patients with
ischemic heart disease (IHD) receiving an antithrombotic therapy. Approaches to
risk stratification for GI bleeding and correction of modifiable factors that
determine the probability of such events are addressed in detail.
Recommendations ... |
26,314 | [Gastrointestinal Bleeding in Patients with Coronary Heart Disease: Preventive
Options]. | Extensive use of antithrombotic drugs (ATD) in patients with ischemic heart
disease (IHD), on the one hand, provides a considerable decrease in the risk for
development of life-threatening cardiovascular complications but on the other
hand, is associated with a risk of gastrointestinal bleedings (GIB), which may
de... |
26,315 | [Peripartum cardiomyopathy or takotsubo cardiomyopathy? The clinical case with
arterial hypotension and pulmonary edema]. | A 29-year old female patient without a history of cardiovascular diseases was
admitted on emergency to a surgical hospital with acute calculous cholecystitis
in 3 months after uncomplicated term birth. During laparoscopic cholecystectomy,
she developed arterial hypotension with pulmonary edema, which required
intra... |
26,316 | [Combination therapy at an early stage of the novel coronavirus infection
(COVID-19). Case series and design of the clinical trial "BromhexIne and
Spironolactone for CoronаvirUs Infection requiring hospiTalization (BISCUIT)"]. | The article focuses on effective treatment of the novel coronavirus infection
(COVID-19) at early stages and substantiates the requirement for antiviral
therapy and for decreasing the viral load to prevent the infection progression.
The absence of a specific antiviral therapy for the SARS-CoV-2 virus is stated.
The... |
26,317 | [ECG changes in COVID-19]. | Aim To evaluate changes in 12-lead ECG in patients with coronavirus
infection.Materials and methods This article describes signs of
electrocardiographic right ventricular "stress" in patients with COVID-19. 150
ECGs of 75 COVID-19 patients were analyzed in the Institute of Cardiology of the
National Medical Re... |
26,318 | Prediction-Determining Outcomes and Their Predictors in Atrial Fibrillation
Patients Receiving Multicomponent Antithrombotic Therapy in Real Clinical
Practice. | Aim Searching for clinical, angiographic, and biochemical predictors of
cardiovascular complications (CVC) and hemorrhagic complications in patients
with atrial fibrillation (AF) receiving a multicomponent antithrombotic therapy
(MAT) for an elective percutaneous coronary intervention (PCI). Patients with
isch... |
26,319 | [The Risk of Developing Ischemic Stroke in Patients After Exacerbation of
Ischemic Heart Disease]. | Aim To develop a model for evaluating the risk of stroke in patients after
exacerbation of ischemic heart disease who were admitted to the hospitals
included into a vascular program.Materials and methods This study included 1803
patients with acute coronary syndrome (ACS) from four institutions of Moscow,
Kaza... |
26,320 | [4D FLOW Magnetic Resonance Imaging in the Study of Blood Flow in Patients With
Aortic Coarctation in the Long-Term After Surgery]. | Aim Comprehensive evaluation of blood flow in the thoracic aorta using a
software for 4D processing of magnetic resonance (MR) images of the heart and
blood vessels (4D Flow) in patients with aortic coarctation in the late
postoperative period.Materials and methods The MR study of the heart was
performed for 1... |
26,321 | [Positive Effects of Perindopril on Microvascular Vessels in Patients With
Chronic Heart Failure]. | Aim To evaluate the effect of 12-month perindopril treatment on structure
and function of microvasculature (MV) in patients with chronic heart failure
with preserved (HFpEF) and intermediate (HFiEF) left ventricular ejection
fraction.Material and methods 30 patients with HFpEF and HFiEF were evaluated.
Perind... |
26,322 | [Experience of the use of the PCSK9 inhibitor Alirocumab in patients with
extremely high cardiovascular risk]. | Aim To study the efficacy and safety of alirocumab in patients with high and
very high cardiovascular risk in the Republic of Karelia and to evaluate their
compliance with the alirocumab therapy.Materials and methods Study design:
observational, noncomparative. The observation group consisted of 9 patients
receivin... |
26,323 | [Polymorphic locus rs1061624 of the ТNFR2 gene is associated with the
development of arterial hypertension in males]. | Aim To study the involvement of cytokine polymorphous loci in development of
arterial hypertension (AH) in men from the Central Black Earth region of
Russia.Materials and methods 821 men were evaluated, including 564 patients with
AH and 257 individuals of the control group. Analysis of 8 cytokine
mononucleotide po... |
26,324 | [Comparative analysis of self-care assessment scales in patients with chronic
heart failure, advantages and disadvantages]. | Aim To compare Russian versions of the scales for assessment of self-care
ability in patients with chronic heart failure (CHF), European Heart Failure
Self-Care Behavior Scale (EHFScBS_9) and The Self-Сare of Heart Failure Index
(SCHFI, version 6.2).Materials and methods Assessment of the self-care ability
was perf... |
26,325 | [The effectiveness of radiofrequency ablation and repeated cardioversion in
combination with antiarrhythmic drug therapy in maintaining stable sinus rhythm
in patients with atrial fibrillation and heart failure]. | Aim To compare the efficacy of radiofrequency ablation (RFA) and antiarrhythmic
therapy (AAT) in patients with atrial fibrillation (AF) and chronic heart
failure (CHF) during 12-month observation.Materials and methods This
prospective, nonrandomized comparative observational study included 130 patients
with AF (men... |
26,326 | [Role of markers of inflammation and endothelial dysfunction in the prognosis of
the development of cardiovascular complications in patients with coronary artery
disease and metabolic syndrome after coronary stenting]. | Aim To study the role of inflammation markers and endothelial dysfunction in
predicting the risk of cardiovascular event following a percutaneous coronary
intervention (PCI) in patients with ischemic heart disease (IHD) and metabolic
syndrome (MS).Materials and methods 80 patients (72 men; median age, 56 (50;63)
ye... |
26,327 | [Modern approaches to the organization of care for patients with heart failure]. | Chronic heart failure (CHF) is a wide-spread disease (from 7 to 10% in the
Russian Federation) and tends to grow. Frequent, repeated hospitalizations of
CHF patients are due to insufficient compliance of patients with the treatment
and the absence of continuity in management of patients between the hospital and
out... |
26,328 | [The soluble guanylate cyclase stimulator riociguat is the first-line therapy
for chronic thromboembolic pulmonary hypertension patients]. | Chronic thromboembolic pulmonary hypertension (CTEPH) is a precapillary type of
pulmonary hypertension with chronic obstruction of large and medium branches of
pulmonary arteries along with secondary alterations in pulmonary
microcirculation, which cause progressive increases in pulmonary vascular
resistance and pu... |
26,329 | [Evidence-Based Information Which Could Influence Arterial Hypertension
Treatment Approach after Publication of SPRINT Trial Results]. | The article discusses results of secondary analysis of the data obtained in the
SPRINT study and published in recent years. Unresolved issues in the tactics of
managing patients with arterial hypertension are discussed. One of such issues
is choosing an optimum level of blood pressure (BP) for a subgroup of patients... |
26,330 | [Ways to solve the problem of heart failure statistics in clinical practice]. | For organization of health care, it is important to know the requirement for its
individual types, including the number of hospitalizations and the use of
expensive technologies. Heart failure (HF) syndrome in patients with
cardiovascular diseases often determines their severity and prognosis. However,
being a comp... |
26,331 | [Predictors of Coronary Plaque Vulnerability in Patients with Stable Coronary
Artery Disease]. | Aim To identify new predictors for vulnerability of atherosclerotic
coronary plaques in patients with stable ischemic heart disease (sIHD).Material
and methods This prospective, single-center study included 58 patients with
sIHD. Unstable plaques were detected with virtual histology intravascular
ultrasound o... |
26,332 | [Prognostic significance of arterial stiffness parameters in the identification
of very high-risk patients]. | Over the past few decades, much attention has been paid to the study of the
properties of the vascular wall and its role in predicting cardiovascular
events. The testing of new indicators characterizing cardiovascular risk is
being actively conducted. The study included 288 men aged 40 to 60 years (mean
age 51.6 ± ... |
26,333 | [Ivabradine for Treatment of Heart Failure with Preserved Ejection Fraction]. | Aim To evaluate the effect of combination ivabradine-containing therapy for
chronic heart failure (CHF) with preserved ejection fraction on quality of life
(QoL) and the primary composite endpoint during a one-year follow-up.Material
and methods This study included 160 patients aged 45 to 65 years with NYHA
f... |
26,334 | [Machine Learning Methods for Prediction of Hospital Mortality in Patients with
Coronary Heart Disease after Coronary Artery Bypass Grafting]. | Aim To compare the accuracy of predicting an in-hospital fatal outcome for
models based on current machine-learning technologies in patients with ischemic
heart disease (IHD) after coronary bypass (CB) surgery.Material and methods A
retrospective analysis of 866 electronic medical records was performed for
pa... |
26,335 | Genetic Variants rs1049255 CYBA and rs2333227 MPO are Associated with
Susceptibility to Coronary Artery Disease in Russian Residents of Central
Russia. | Aim To study association of single-nucleotide polymorphisms rs1049255 CYBA
and rs2333227 MPO with development of ischemic heart disease (IHD) in Russian
residents of Central Russia.Material and methods The study material was DNA
samples from 436 patients with IHD (265 men, 171 women; mean age, 61 years) and
3... |
26,336 | [Is the N-terminal pro-B-type natriuretic peptide a predictor of cardiovascular
events in hemodialysis patients?]. | Aim To evaluate the role of N-terminal pro-hormone brain natriuretic peptide
(NT-proBNP) as a predictor of cardiovascular events (CVE) in patients receiving
programmed hemodialysis (PHD).Material and methods This study included 74
patients (men, 64.8 %) older than 18 years receiving PHD. Data were processed
using m... |
26,337 | Management of radio-contrast allergy in radio-contrast allergic patients
undergoing coronary angiography and intervention. | Objectives Radiocontrast agents (RCA) allergy occurs in 0.04 % - 0.22 % of
patients. However, the risk of allergic reaction increases as 16 % to 35 % in
patients with prior RCA allergy. Herein we reported our experience in patients
with a prior history of RCA induced anaphylaxis who underwent coronary
angiography (... |
26,338 | [Adherence to the treatment of pa-tients in the long-term supervision period
after myocardial infarction (according to the REGATA register)]. | Aim To study long-term compliance with treatment in patients included into the
REGistry of pATients after myocArdial infarction (REGATA).Material and methods
In 2012-2013, the study included 481 patients with a history of myocardial
infarction (MI) who visited the district outpatient clinic. Median age was 72
[62;7... |
26,339 | [Markers of endothelial dysfunction in patients with arterial hypertension
exposed to occupational irradiation of low intensity]. | Aim To study the association between concentrations of endothelial dysfunction
(ED) markers and arterial hypertension (AH) in people who were exposed to
long-term action of "low-dose" ionizing radiation.Material and methods The study
subjects were men of middle age (45-55 years) who were workers of the Siberian
Int... |
26,340 | [Prognostic value of the ultrasonic determination of the degree of interstitial
edema in patients with intermediate ejection fraction of the left ventricle
after treating acute decompensation of heart failure]. | Aim To study ultrasonic characteristics of lung tissue in patients with heart
failure with left ventricular (LV) mid-range ejection fraction (HFmEF) and
predictive value of these characteristics after reversing acute decompensated
heart failure (ADHF).Material and methods Ultrasonic characteristics of lung
tissue w... |
26,341 | [Influence of Omega-3 PUFA on Non-invasive factors determining the risk of
arrhYthmias eXcess and sudden cardiac death in patients with HFpEF with ischemic
etiology (ONYX)]. | Aim Patients with heart failure with reduced left ventricular (LV) ejection
fraction (HFrEF) who have had acute myocardial infarction have an unfavorable
prognosis, largely due to ventricular arrhythmias (VA) and risk of sudden
cardiac death (SCD). The optimal treatment (triple neurohormonal blockade plus
implantab... |
26,342 | [Prevention of thromboembolic complications during cardioversion and catheter
ablation in patients with atrial fibrillation: review of key randomized trials]. | This review focuses on the relevance of sinus rhythm control in patients with
atrial fibrillation in real-life clinical practice and specific clinical
features of patients with this arrhythmia. The authors presented current
guidelines on prevention of thromboembolic complications and a review of results
from major ... |
26,343 | [The Choice of Priorities in Contemporary Comparative Trials: Superiority vs non
Inferiority. Causes and Effects]. | The article compares two statistical approaches, which are commonly used in
current comparative studies, a hypothesis that a drug is superior over another
one (superiority) and a hypothesis that a drug is not inferior to another one in
the efficacy and safety (non-inferiority). Using the example of specific
studies... |
26,344 | [Possibilities of Stress Computed Tomography Myocardial Perfusion Imaging in the
Diagnosis of Ischemic Heart Disease]. | Computed tomography angiography (CT-angiography, CTA) allows noninvasive
visualization of coronary arteries (CA). This method is highly sensitive in
detecting coronary atherosclerosis. However, standard CTA does not allow
evaluation of the hemodynamic significance of found CA stenoses, which requires
additional fun... |
26,345 | [Comorbidity of arterial hyperten-sion and tension-type headache]. | Arterial hypertension (AH) and exertional headache (EHA) are comorbidities. The
article presents a nonsystematic review focused on studying the AH+EHA
phenotype. The authors addressed the history of studying the phenotype, several
theories about its pathophysiological causes (psychosomatic, neuroanatomical,
and bar... |
26,346 | Results of Open-Label non-Randomized Comparative Clinical Trial: "BromhexIne and
Spironolactone for CoronаvirUs Infection requiring hospiTalization (BISCUIT). | Introduction The aim of this study was to assess the efficacy and safety of a
combination of bromhexine at a dose of 8 mg 4 times a day and spironolactone 50
mg per day in patients with mild and moderate COVID 19.Material and methods It
was an open, prospective comparative non-randomized study. 103 patients were
in... |
26,347 | [Right ventricular systolic dysfunction as a predictor of adverse outcome in
patients with COVID-19]. | Aim To analyze survival of patients with COVID-19 based on echocardiographic
(EchoCG) criteria for evaluation of the right ventricular (RV) systolic
function.Material and methods Data of patients were retrospectively evaluated at
the Center for Medical Care of Patients with Coronavirus Infection. Among 142
primaril... |
26,348 | [How evaluate results of treatment in patients with COVID-19? Symptomatic
Hospital and Outpatient Clinical Scale for COVID-19 (SHOCS-COVID)]. | Aim Development of a novel scale for assessing medical state in patients with
new coronavirus infection based on clinical and laboratory disease severity's
markers, named SHOKS-COVID scale.Material and Methods Clinical Assessment Scale
(SHOKS-COVID) is based on1: clinical parameters (respiratory rate, Body
temperat... |
26,349 | [Level of the growth differentiation factor-15 in patients with acute myocardial
infarction]. | Aim To reveal relationships between growth differentiation factor-15 (GDF-15)
and laboratory and instrumental indexes in patients with myocardial infarction
in acute phase.Material and methods The study included 118 patients younger than
70 years with ST-segment elevation or non-ST segment elevation myocardial
infa... |
26,350 | [Sechenov First Moscow State Medical University of the Ministry of Health of the
Russian Federation (Sechenov University), Moscow]. | Aim To study changes in markers for myocardial direct injury and
dysfunction and endothelial dysfunction (ED) indexes in patients with indolent
lymphoma during the antitumor treatment.Material and methods Current antitumor
therapy for lymphoma is often associated with cardio- and vasculotoxicity,
studying of ... |
26,351 | [Safety and Effectiveness of Volumetric Computed Tomography of the Heart in
Combination with a PharmacologicaTest with Adenosine Triphosphate in the
Diagnosis of Coronary Heart Disease]. | Aim To evaluate safety and efficacy of sodium adenosine triphosphate (ATP)
as a vasodilator in assessment of left ventricular (LV) myocardial perfusion and
in verification of ischemia by cardiac volumetric computed tomography
(CT).Material and methods The study included 58 patients with suspected
ischemic hea... |
26,352 | [Echocardiography in the Assessment of Intraventricular Flows and Pressure
Gradients in Obstructive Hypertrophic Cardiomyopathy]. | Aim To evaluate results of myomectomy by intraventricular pressure
gradients (IVPG) and blood flows in patients with obstructive hypertrophic
cardiomyopathy (OHCMP).Material and methods The study included a total of 76
subjects, 42 patients with OHCMP (mean age, 39±7 years) and 34 healthy
volunteers (mean age... |
26,353 | [Factors Associated with the Increase in Spatial and Frontal QRS-T Angles in
Patients with Inferior Myocardial Infarction]. | Aim To identify clinical, echocardiographic, and angiographic factors
related with an increase in the frontal QRS-T angle (fQRS-T) and the spatial
QRS-T angle (sQRS-T) in patients with inferior myocardial infarction.Material
and methods The study included 128 patients aged (median [25th percentile; 75th
perce... |
26,354 | Early Predictors of Heart Failure Progression in Patients After Myocardial
Infarction. | Aim To identify early predictors for progression of chronic heart failure
(CHF) in patients with ST-segment elevation myocardial infarction
(STEMI).Material and methods The study included 113 patients with STEMI aged 52
(95 % confidence interval, 36 to 65) years. 24-h ECG monitoring was performed
with assessm... |
26,355 | [Safety performance of rivaroxaban versus warfarin in patients with atrial
fibrillation and advanced chro-nic kidney disease]. | Aim To evaluate safety of using rivaroxaban in patients with stage 4 chronic
kidney disease (CKD) or transient, stable decline of glomerular filtration rate
(GFR) to 15-29 ml /min / 1.73 m2 in the presence of atrial fibrillation
(AF).Material and methods This multicenter prospective, randomized study
included patie... |
26,356 | [Efficacy and Safety of Combined Treament with Ivabradine and Metoprolol in
Patients with Stable Angina Pectoris - a Systematic Review]. | This article presents results of a systematic review, which was designed for
evaluating the effect of combination treatment with ivabradine and metoprolol on
heart rate, frequency of angina attacks, frequency of using short-acting
nitrates, and angina severity. The analysis included data from three large
observatio... |
26,357 | New Possibilities to Reduce the Residual Risk in Patients with Ischemic Heart
Disease. | Despite a significant progress of the recent decades, incidence of
cardiovascular complications in patients with manifest, stable ischemic heart
disease (IHD) is still high. Furthermore, this patient group is heterogenous;
individuals with a higher risk of cardiovascular complications can be isolated
from this grou... |
26,358 | The Role of Neprilysin Inhibitors in the Treatment of Heart Failure with
Preserved Ejection Fraction. | Clinical and hemodynamic aggravation of heart failure with preserved ejection
fraction (HFpEF) is largely due to progression of left ventricular (LV)
diastolic dysfunction. The key role in the normal maintenance of diastolic
function is played by a high level of activity of the intracellular signaling
axis, cyclic ... |
26,359 | [Circulating Neuregulin-1 and Chronic Heart Failure with Preserved Ejection]. | Chronic heart failure (CHF) with preserved ejection fraction (CHFpEF) is an
unsolved, socially relevant challenge since it is associated with a high level
of morbidity and mortality. Early markers for this pathology are unavailable,
and therapeutic approaches are undeveloped. This necessitates extensive studying
th... |
26,360 | [Clinical Manifestation of Stressful Cardiomyopathy (Takotsubo Syndrome) and the
Problem of Differential Diagnosis with Acute Myocardial Infarction]. | The presented data show that tacotsubo syndrome (TS) is characterized by the
absence of coronary artery obstruction, cardiac contractile dysfunction, apical
ballooning, and heart failure, and in some patients, ST-segment elevation and
prolongation of the QTc interval. Every tenth patient with TS develops
ventricula... |
26,361 | [Surgical treatment of rupture of the anterior wall of the left ventricle in the
apical region with the formation of a false aneurysm in the acute stage of
myocardial infarction]. | One of the most dangerous complications of acute myocardial infarction (MI) is
external or internal left ventricular rupture. Despite multiple studies on early
diagnostics and algorithms for routing of patients with complicated MI,
mortality in this patient group remains extremely high. Presently available
publicat... |
26,362 | [Data of coronary angiography and rheological properties of erythrocytes in non
ST-elevation acute coronary syndrome]. | We assessed character and extent of coronary vessels involvement in 27 patients
with non ST-elevation acute coronary syndrome (NSTEACS) and compared angiography
data with rheological properties of erythrocytes of patients and 30 practically
healthy men. Stenoses of main branches of coronary vessels were found almost... |
26,363 | [Predictors of stent thrombosis in patients with ST-elevation acute coronary
syndrome subjected to primary coronary artery intervention]. | Basing on complex evaluation of clinical, angiographic, and laboratory data we
revealed predictors of stent thrombosis in patients with ST-elevation acute
coronary syndrome (ACS) subjected to percutaneous coronary interventions (PCI).
Among studied sample of patients (n=124) we distinguished a group of patients
wit... |
26,364 | [Clinical- functional assessment of organoprotective efficacy of enalapril and
telmisartan in patients with arterial hypertension]. | Effect of enalapril and telmisartan on hemodynamic indices,
structural-functional parameters of the left ventricle, and vasomotor function
of arterial endothelium was studied in 49 patients (mean age 48.3+/-3.2 years)
with 1-2 degree arterial hypertension (AH) and abnormal relaxation type of left
ventricular diasto... |
26,365 | [Selection of rational combinations of indapamide with various of calcium
antagonists in patients with arterial hypertension]. | We studied 89 patients with II degree arterial hypertension (age 43-67 years).
Before and in 24 weeks after therapy we carried out 24-hour monitoring of
arterial pressure and Doppler echocardiography. Patients were divided into 2
groups. Combination therapy with indapamide and verapamil retard, indapamide and
amlod... |
26,366 | [Functional screening test for latent arterial hypertension detection in young
patients]. | We assessed diagnostic value of acute-hypoxia test (AHT) for detection of latent
arterial hypertension in 317 young persons from different social groups (mean
age 25.6+/-5.1 yrs) without clinical signs of cardiovascular diseases. We
performed AHT and ambulatory blood pressure monitoring (ABPM). Sensitivity and
spec... |
26,367 | [Indices of static and dynamic components of pressure load (assessed by 24-hour
blood pressure monitoring) and the state of renal function in patients with
essential hypertension]. | Aim of this study was to evaluate possible relationship between parameters of
blood pressure (BP) profile and glomerular filtration rate in patients (pts)
with I-II stage essential hypertension (EH). Material and methods. We studied
120 pts (97 men), aged 23-65 (50,2+/-0,6) years with I (n=98) and II (n=22)
stage E... |
26,368 | [Wall motion abnormalities and hemodynamic parameters in patients with left
bundle branch block during exercise echocardiography]. | Study aim was to investigate dynamics of local contractility and hemodynamic
parameters during exercise stress echocardiography (EEcho) in patients with left
bundle branch block (LBBB). We examined 23 patients (15 men, 8 women) aged 48-65
years (mean age 53.9+/-8.1 years). Bicycle EEcho was accomplished according to... |
26,369 | [Stabilization of cellular membranes as a target of vascular therapy]. | We present data of the study of effect of trimetazidine MB on the state of
cellular membranes assessed on lymphocytes as highly sensitive model of hypoxia
and endothelial dysfunction. Detection of external cytoplasmatic membrane
blebbing and registration of quantity of membrane released microparticles by the
method... |
26,370 | [Torasemide is the effective loop diuretic for long-term therapy of arterial
hypertension]. | Torasemide is a loop diuretic and has been used for the treatment of both acute
and chronic congestive heart failure (CHF) and arterial hypertension (AH).
Torasemide is similar to other loop diuretics in terms of its mechanism of
diuretic action. It has higher bioavailability (>80%) and a longer
elimination half... |
26,371 | [Possibilities of the use of moxonidine in the treatment of arterial
hypertension in patients with metabolic syndrome and diabetes]. | In pathogenesis of arterial hypertension (AH) and metabolic syndrome (MS)
important role plays activation of sympathetic part of vegetative nervous system
(VNS). Centrally acting antihypertensive drugs promote lowering of tone of its
nuclei. Moxonidine belongs to this group of antihypertensive preparations.
Mechani... |
26,372 | [Resident cardiac stem cells]. | The search for sources of stem/progenitor cells the use of which has a potential
to affect course of ischemic heart disease and chronic heart failure is
conducted nowadays in many countries. Resident cardiac stem cells (CSC) were
revealed during recent years on the basis of expression of c-kit, sca-1, MDR1,
and isl... |
26,373 | [The statistical analysis of prevalence of anemia in patients with chronic heart
failure]. | Development of anemia in patients with congestive heart failure (CHF) is
associated with worsening of disease what has been shown in numerous trials.
According to various data prevalence of the syndrome varies depending on chosen
populations of patients and criteria of anemia. We observed 1122 patients (mean
age 71... |
26,374 | [High level of lipoprotein (a) as a predictor of poor long-term prognosis after
coronary artery bypass surgery]. | Study aim was to investigate the association of lipoprotein (a) [Lp(a)] level
with the development of cardiovascular complications in long-term follow-up
period after coronary artery bypass grafting (CABG). Patients with chronic
ischemic heart disease (IHD) (n = 361, 88% men, mean age 55 +/- 9 years) who had
had CA... |
26,375 | [Prognostic value of aortic stenosis in patients after acute coronary syndrome]. | With the aim to assess prevalence of aortic stenosis (AS) and prognostic value
of its detection among survivors of acute coronary syndrome (ACS) we examined
851 patients included into multicenter prospective study of risk factors of
serious vascular events and death after acute coronary syndrome. The patients
were ... |
26,376 | [Dynamics of morphological structures of platelets in patients with ischemic
heart disease in dependence on blood levels of fatty acids]. | Levels of fatty acids in platelets of ischemic heart disease (IHD) patients (n =
39) has been compared with those in healthy subjects (n = 12). Increased content
of arachidonic acid and thromboxane A2 in platelets of IHD patients forms
thrombogenic picture of IHD. High level of fibrinogen and decrease in heparin
an... |
26,377 | [Own and parental predictors of high level of low density lipoprotein
cholesterol at children of persons with "premature" coronary heart disease]. | AIM: To elucidate associations between high low density lipoprotein cholesterol
(LDL-C) in children of persons with premature coronary heart disease (PCHD) and
their own and parental characteristics.
METHODS: We examined members of 282 families: probands (n = 262, 70.1% men) with
PCHD (onset before 55 [men] or 60 [w... |
26,378 | [Percutaneous coronary interventions in patients with acute myocardial
infarction after unsuccessful thrombolysis]. | In 176 patients with acute myocardial infarction admitted to N.V. Sklifosofsky
institute of urgent aid in 2003-20007 we compared efficacy of 3 strategies of
treatment after unsuccessful thrombolytic therapy (TLT): percutaneous coronary
intervention (PCI) during first 24 hours (n = 30), PCI on days 2 or 3 (n = 38);
... |
26,379 | [First experience of clinical use of new class III antiarrhythmic agent
niferidil in patients with persistent atrial fibrillation and flutter]. | The aim of the study was to evaluate the efficacy and safety of administered
intravenously niferidil in doses 10, 20 and 30 mkg per kg in patients with
persistent atrial fibrillation (AF) and flutter (AFL) for pharmacological
cardioversion. The study included 30 patients (22 male) with persistent AF (n =
28) and AF... |
26,380 | [Antitachycardia pacing in patients with implanted cardioverter defibrillators]. | Efficacy and safety of the use of antitachycardia pacing (ATP) function in 54
patients (age 18-54, mean age 62.2 +/- 11.5 years, 6 women) with cardioverter
defibrillators implanted for prevention of sudden death. Duration of follow-up
was 6-64 months (mean 27.3 +/- 8.6 months). Ischemic heart disease (IHD) was
etio... |
26,381 | [Achievements and problems of modern trials of antihypertensive drugs]. | Most important value of lowering of substantially elevated arterial pressure
(AP) for improvement of outcomes in patients with arterial hypertension (AH) was
convincingly confirmed by large truly placebo controlled randomized clinical
trials (RCT) with the use of mainly diuretics, and/or beta-adrenoblockers in the
... |
26,382 | [Pulmonary arterial hypertension: changing approaches to management]. | The review is devoted to different aspects of pulmonary arterial hypertension
(PAH); new classification of PAH is published in 2010. There are idiopathic PAH
and PAH associated with other diseases. Current guidelines recommend to treat
PAH only after the verification of diagnosis with right heart catheterization
an... |
26,383 | [Factors determining clinical effectiveness of clopidogrel and prognosis of
patients with stable ischemic heart disease]. | Aim of the study was to elucidate genetic and drug factors affecting efficacy of
clopidogrel in patients with ischemic heart disease - inhabitants of central
region of Russian Federation. We included 399 patients with IHD (79% men, mean
age 58.3+/-9 years) receiving long term therapy with clopidogrel 75 mg/day
(dur... |
26,384 | [Novel method of analysis of risk of development of ischemic heart disease with
the use of genomic and computer technologies]. | AIM: to assess effectiveness of the use of modern methods of prognostication for
assessment of risk of development of ischemic heart disease (IHD).
MATERIAL AND METHODS: We examined 131 patients with diagnosis of IHD verified by
coronary angiography and 159 subjects of control group. Initial information on
each pati... |
26,385 | [Prognostic value of levels of brain natriuretic peptide and genetic factors in
patients after acute coronary syndrome]. | Prognostication of the course of disease in patients with high risk of
unfavorable outcome of ischemic heart disease (IHD) is of great importance for
creation of individualized strategy of treatment. We have investigated
contribution of levels of brain natriuretic peptide (BNP) and genetic factors in
the risk of de... |
26,386 | [Echocardiographic assessment of myocardial fibrosis in young men with arterial
hypertension and different types of left ventricular remodeling]. | In order to study structural functional characteristics of myocardium including
parameters of myocardial fibrosis according echocardiography data in men with
various levels of arterial pressure (AP) we examined 215 men aged 18-25 (mean
21.1+/-0,1) years with history of elevated AP at casual measurement. AP
phenotyp... |
26,387 | [Clinico-statistical analysis of arterial hypertension complicated with
hypertensive crisis in Moscow in 2005-2009]. | Clinicostatistical analysis of arterial hypertension complicated with
hypertensive crisis using data of Moscow A.S.Puchkov Station of Urgent and
Emergent Medical Aid revealed 14% rise in number of hypertensive crises during
the period from 2005 to 2009. Number of hypertensive crises increased among
persons of young... |
26,388 | [Acute management at the rising of arterial pressure which is not menacing to a
life]. | 491 hypertensive (non life threatening) patients were examined for hemodynamic
changers and variance of the sinus rhythm after administration of clonidine,
nifedipine, captopril, and mocsonidine. BP was done by the caff method,
hemodynamic by the integral rheography, variance of the sinus rhythm - according
to the ... |
26,389 | [Clinical and angiographical factors influencing improvement of left ventricular
function after implantation of dare-metal stents in patients with chronic total
occlusions of coronary arteries]. | INTRODUCTION: Effect on left ventricular (LV) contractility of percutaneous
coronary interventions (PCI) with implantation of bare-metal stents in patients
with chronic total occlusions (CTO) of coronary arteries (CA) has not been
completely studied. Aim of this study was to assess effect of PCI with
implantation o... |
26,390 | [Depressive symptoms worsen cardiovascular prognosis and shorten length of life
in patients with arterial hypertension and ischemic heart disease]. | The KOORDINATA study (clinical epidemiological program of investigation of
depression in cardiological practice in patients with arterial hypertension and
ischemic heart disease) was a prospective 3 year long multicenter study of
effects of depressive and anxiety states on the course and prognosis of ischemic
heart... |
26,391 | [Anatomical, functional, and genetic peculiarities of myocardial hypertrophy in
athletes]. | "Athletes Heart" (AH) is a complex of structural, electrophysiological, and
functional changes - a consequence of physiological adaptation to regular
physical exercise. AH is characterized by biventricular hypertrophy of
ventricular myocardium at the background of unchanged parameters of systolic and
diastolic func... |
26,392 | [Peculiarities of morphology and mechanisms of pathogenesis of hypertrophic
cardiomyopathy]. | Understanding the molecular basis and cell mechanisms, clinical course, and
treatment of hypertrophic cardiomyopathy (HCMP) has progressed substantially in
the last decade. The majority of genetic mutations associated with HCMP occur in
genes encoding sarcomeric proteins, which are expressed only in cardiomyocytes. ... |
26,393 | [Catheter ablation for atrial fibrillation: clinically established or still an
experimental method]. | Interventional treatment for atrial fibrillation has been introduced as a
therapeutic option since the pulmonary veins (PV) have been discovered as the
dominant sources of paroxysmal atrial fibrillation (PAF). Elimination of PV
conduction is the initial goal during catheter ablation in this setting. The
success rat... |
26,394 | [Myocardial infarction and stress at work place and in the family: 10-year risk
of development in an open population of 2564 year old men (epidemiological study
in a framework of the WHO program MONICA-PSYCHOSOCIAL)]. | With the aim of assessment of 10 year risk of myocardial infarction (MI)
development in men in dependence on stress at work place and in the family in a
framework of the WHO program "MONICA-PSYCHOSOCIAL" we examined random
representative sample of men (n=657) aged 25-64 years inhabitants of one of
districts in Novo... |
26,395 | [Prediction of left ventricular remodeling after acute myocardial infarction]. | Prediction of adverse left ventricular remodeling after acute myocardial
infarction (AMI) may have important clinical implications. In this study, we
evaluated the incidence of unfavorable changes of left ventricular volumes and
ejection fraction after AMI. The ability of several cardiac markers,
electrocardiograph... |
26,396 | [Prognostic value of various markers of inflammation in ST-elevation myocardial
infarction]. | We measured levels of several parameters of immune inflammation (interleukins
[IL] 1, 6, 8, 10, 12, tumor necrosis factor [TNF], serum neopterin, C-reactive
protein) on days 10-14 after onset of ST segment elevation myocardial infarction
(MI) and related them to results of 12 months follow up. Elevated titers of
IL... |
26,397 | [Lornoxicam for prevention of myocardial injury during acute ST-elevation
myocardial infarction]. | 10% of patients with acute ST-elevation myocardial infarction (STEMI) treated
with reperfusion therapy fail to develop an enzyme rise, but do exhibit
transient ECG changes, which are consistent with an aborted myocardial
infarction. Following reperfusion by primary PCI in STEMI, oxidative stress and
an inflammatory... |
26,398 | [Key laboratory diagnostic biomarkers of coronary atherosclerosis]. | Laboratory lipid and lipoprotein biomarkers (total cholesterol - CH,
triglycerides - TG, low-density and high-density lipoprotein cholesterol-
LDL-CH, HDL-CH, apolipoproteins B and A1 - apoB, apoA1), carbohydrate biomarkers
(plasma glucose, basal insulin), high sensitive C-reactive protein (hsCRP) and
oxidative bio... |
26,399 | [Changes of content of regulatory lymphocytes and concentration of soluble
interleukine-2 receptor in blood of patients with ischemic heart disease after
coronary artery angioplasty with implantation of stents with rapamycin
covering]. | We studied dynamics of content of subpopulation of lymphocytes including
regulatory and effector T-lymphocytes as well as concentration of soluble form
of interleukine-2 receptor (sCD25) in peripheral blood of patients after
coronary stenting (CS) with implantation of stents with rapamycin covering
(SRC). We includ... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.