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26,400 | [Association of C677T gene polymorphism of methylenetetrahydrofolate reductase
with insulin resistance among Kirghizes]. | AIM: To study an association of C677T gene polymorphism of
methylenetetrahydrofolate reductase (MTHFR) and insulin resistance (IR) among
ethical Kirghizes.
METHODS: 132 Kirghiz patients with IR according to HOMA index (n=132) and sex
and age matched patients without IR, diabetes mellitus (DM) type 2 or metabolic
sy... |
26,401 | [Diagnosis and classification of mitral valve prolapse in children and
adolescents]. | We examined 1734 children and adolescents with admittance diagnosis mitral valve
prolapse (MVP) and confirmed its presence using accepted Framingham criteria in
32.3% of cases. Reason for overdiagnosis in other cases was incorrect
interpretation of auscultation or echocardiography data. Most often MVP was
familial ... |
26,402 | [Hyperuricemia in chronic heart failure]. | Development of hyperuricemia is associated with excessive body mass, insulin
resistance, metabolic syndrome, overuse of diuretics, elderly age, and abnormal
renal function. Data are accumulated on existence of links between elevated uric
acid level and arterial hypertension, diabetes mellitus, ischemic heart disease... |
26,403 | [Permanent cardiac pacing in vasovagal syncope and carotid sinus syndrome]. | Vasovagal syncope and carotid sinus syndrome are common conditions in young and
elderly people, respectively, mostly with benign prognosis. Nevertheless, severe
or "malignant" syncopal attacks in some patients may be associated with
life-threatening injury. Unfortunately, up to now almost all drug trials have
faile... |
26,404 | [Utility of the use of computer monitoring pulse oximetry for screening of
obstructive sleep apnea]. | This paper contains description of possibilities of the use of the computer
monitoring pulse oximetry for (CMPO) diagnosis of obstructive sleep apnea
syndrome at the level of practical health care and presentation of data on
sensitivity and specificity of this method in various groups of patients. It is
shown that ... |
26,405 | [Metabolic syndrome in families of patients with premature coronary heart
disease: impact of 2009 Joint Interim Statement criteria]. | AIM: To assess effect of transition from metabolic syndrome (MS) definition of
International Diabetic Federation (IDF, 2005) to definition of Joint Interim
Statement (JIS, 2009) on proportion of persons with MS among patients with
premature coronary heart disease (CHD) and members of their families.
MATERIAL: We exa... |
26,406 | [Pleiotropic effects of nicotinic acid therapy in men with coronary heart
disease and elevated lipoprotein(a) levels]. | PURPOSE: To assess effects of niacin on risk factors of atherosclerosis in men
with coronary heart disease (CHD) and high lipoprotein(a) [Lp(a)] levels.
MATERIAL AND METHODS: Sixty men (mean age 54+/-6 years) with angiographic
evidence of CHD were randomized into two groups. Active group (n=30) received
extended rel... |
26,407 | [Analysis of causes of development of anemia in patients with chronic heart
failure]. | High prevalence of anemia and its direct relation with morbidity and mortality
in congestive heart failure (CHF) has been shown in numerous studies. Among
etiology factors of anemia are hemodilution, chronic kidney insufficiency,
deficiency of iron, folate, and vitamin 12, high level of inflammatory
cytokines. Aims... |
26,408 | [The use of screening methods in diagnosis of disturbances of respiration during
sleep in patients with cardiac pathology]. | Disturbances of respiration during sleep especially those of obstructive
character are sufficiently widespread phenomena. In addition to worsening of the
quality of sleep itself they facilitate formation and development of concomitant
pathology of cardiovascular system, endocrine system, cognitive sphere. This
resu... |
26,409 | [Systematic analysis of molecular mechanisms of action of omega-3
polyunsaturated fatty acids on arrhythmia]. | Safe pharmacotherapy and prevention of arrhythmia is an urgent problem of modern
cardiology. Essential micronutrients such as omega-3 polyunsaturated fatty acids
(-3 PUF-) significantly contribute to the metabolic processes in cardiomyocytes
and cardiac conduction system. This article presents a systematic analysis ... |
26,410 | [Diagnosis, sudden death risk stratification, and treatment of main long QT
syndrome molecular-genetic variants]. | Inherited long QT syndrome (LQTS) refers to the primary electrical diseases of
the heart. It is characterized by QT prolongation on resting ECG and syncope due
to life-threatening ventricular arrhythmias. This review focuses on diagnosis,
differential diagnosis, risk stratification of sudden cardiac death, and
trea... |
26,411 | [Drug prevention of pulmonary embolism in orthopedic practice: traditional and
novel approaches]. | We consider in this review traditional and novel approaches to drug prevention
of pulmonary embolism (PE) which in predominant number of cases is related to
deep vein thrombosis of lower extremities. Risk of PE development is especially
high in patients after orthopedic hip or knee surgery. Modern recommendations
c... |
26,412 | [Cystatin C level is independently related to risk of unfavorable outcome after
acute coronary syndrome in individuals with normal or moderately reduced renal
function]. | We studied relation between cystatin C level and risk of unfavorable outcome
(unstable angina, fatal and nonfatal myocardial infarction [MI], fatal and
nonfatal stroke, and death) in patients stabilized after exacerbation of
ischemic heart disease. Patients (n=272) were included on day 10 after onset of
acute coron... |
26,413 | [Effect of the presence of a drug in the list of supplementary drug provision on
compliance to its administration by outpatients with arterial hypertension]. | Aim of the study was to investigate relationship between the presence of a drug
in the list of supplementary drug provision (SDP) and compliance to its
consumption by outpatients with arterial hypertension as well as determination
of the place of SDP in a row of other factors affecting compliance to treatment.
Meth... |
26,414 | [Application of coenzyme Q(10) in combination therapy of arterial hypertension]. | We studied effect of coenzyme Q(10) on 24-hour blood pressure profile and
function of vascular endothelium in patients with essential hypertension.
Coenzyme Q(10) was used as a component of combination therapy comprising
angiotensin converting enzyme inhibitor enalapril. Administration of coenzyme
Q(10) in combinat... |
26,415 | [Clinical value of brain natriuretic peptide level in patients with atrial
fibrillation]. | PURPOSE of this investigation was to study correlation between brain natriuretic
peptide (BNP), extent of cardiac abnormalities, and six minute walk test (6-MWT)
in order to asses diagnostic value of BNP in patients with trial fibrillation
(F), heart failure (HF) and preserved systolic function.
MATERIAL AND METHODS... |
26,416 | [The study of microcirculation in walls of chambers of the heart in patients
with aortic stenosis in dependence on heart failure stage]. | We studied microcirculatory blood flow (MBF) by laser Doppler flowmetry (LDF) in
52 patients with stage III-IV aortic stenosis (AS) and class II-IV chronic heart
failure (CHF). MBF was assessed in walls of right and left cardiac chambers
before and after correction of the defect. Aim of this study was to assess
fun... |
26,417 | [he use ethylmethylhydroxypyridine succinate in the treatment of patients with
heart failure]. | We studied impact of ethylmethylhydroxypyridine succinate n the course of
chronic heart failure during 3 years follow-up after myocardial infarction.
Dynamics of objective and subjective parameters was assessed in 100 patients; 48
patients received conventional therapy (control group) and 52 patients received
conve... |
26,418 | [Eosinophilic cation protein and development of restenosis of drug covered
stents]. | Aim of the study was to assess activation of eosinophils as well as allergic and
inflammatory reactions of the body in development of restenosis after
implantation of stents with drug covering. We included into the study 32
patients with ischemic heart disease (IHD) and stable angina subjected to repeat
coronary an... |
26,419 | [Polymorphisms of 2B-adrenergic receptor and endothelial NO-Synthase genes in
genesis of the hereditary sick sinus node syndrome]. | In this work we have demonstrated for the first time on the clinico-genetic
material association between hereditary sick sinus node syndrome (SSNS) ADRA2B
and eNOS genes polymorphisms. We have established predominance of homozygote
genotype of more rare DD allele in patients with SSNS (28%) compared with
subjects o... |
26,420 | [Fifteen years experience of the use of magnesium preparations in patients with
mitral valve prolapse]. | We followed for 15 years 31 patients with mitral valve prolapse (MVP) who during
follow-up regularly took orotic acid (1500 mg/day) for 3 months twice a year. We
revealed peculiarities of dynamics of clinical picture, their interrelation with
phenotypic manifestations of connective tissue dysplasia, changes of
elec... |
26,421 | [Analysis of efficacy and safety of administration of moxonidine in patients
with arterial hypertension and hypertensive crises]. | In the review we present detailed analysis of antihypertensive action of 3-nd
generation sympatholytic moxonidine. Due to selective interaction with
imidazoline I1-receptors moxonidine diminishes sympathetic activity causing
lowering of peripheral vascular resistance. This leads to significant lowering
of systolic ... |
26,422 | [Platelet aggregation upon acetylsalicylic acid and clopidogrel treatment and
glycoprotein IIb/IIIa content in patients with acute coronary syndrome]. | Interaction between aggregating activity of platelets and glycoprotein (GP)
IIb/IIIa (fibrinogen receptor) content on their surface was investigated in
patients with acute coronary syndrome (ACS). Eighty nine ACS patients were
included into the study - 69 with and 20 without elevation of ST segment. Blood
was colle... |
26,423 | [Possibilities of improvement of prognosis in patients with type 2 diabetes
mellitus after coronary interventions]. | We present results of investigation of fenofibrate in patients with ischemic
heart disease and type 2 diabetes mellitus after myocardial revascularization at
various terms of its administration. We have shown its efficacy in correction of
diabetic dyslipidemia, positive influence on clinical status and long term
re... |
26,424 | [Efficacy of fixed combination amlodipine/valsartan in hospitalized patients
with hypertensive disease]. | Efficacy and tolerability of fixed amlodipine/valsartan combination was studied
in 86 patients with hypertensive disease hospitalized in departments of general
internal medicine or cardiology. All patients had indications for
antihypertensive therapy and were randomized either to fixed combination
amlodipine/valsar... |
26,425 | [Echocardiographic parameters in patients with Wolf-Parkinson-White syndrome
before and during one year after radiofrequency catheter ablation of accessory
atrioventricular junction]. | We present in this paper results of assessment of morphofunctional state of
myocardium in patients with the Wolf-Parkinson-White syndrome before and during
one year after radiofrequency catheter ablation (RFA) of accessory
atrioventricular junction (AAVJ) and comparison of them with analogous
parameters of the grou... |
26,426 | [Clinical value of antracycline toxicity: modern approaches to diagnosis,
prevention, and treatment]. | In this literature review we present analysis of various aspects of the problem
of cardiotoxicity of antracyclines used for the treatment of the breast cancer.
We consider mechanisms of their cardiotoxic action, role of risk factors,
clinical manifestations of acute and chronic cardiotoxicity, and dependence of
the... |
26,427 | [Cyclooxygenase inhibitors and antiplatelet effect of acetylsalicylic acid.
selective approach to nonsteroidal anti-inflammatory drugs in cardiological
practice]. | Nonsteroidal anti-inflammatory drugs (NSAIDs) represent class of medicines which
is wide concerning chemical structure and mechanism of action. In the light of
contradictory data on efficacy and safety of NSAID in cardiovascular patients
selection of most appropriate NSAID (basing on profile of efficacy and safety) ... |
26,428 | [Hypertension, obesity, erectile dysfunction. What kind of drug to choose]. | Hypertension is one of the most common cardiovascular diseases. The development
and progression of hypertension is associated with prolonged hyper activation of
the renin-angiotensin-aldosterone system. ACE inhibitors and angiotensin
receptor blockers (ARBs) are highly effective medicines and are widely used in
the... |
26,429 | [The role of coronary reserve in diagnosis of hemodynamically significant
stenoses in anterior descending and right coronary arteries: transthoracic
ultrasound study]. | Analysis of possibilities of transthoracic echocardiography (TTEchoCG) diagnosis
of hemodynamically significant stenoses of anterior descending and right
coronary arteries (ADCA and RCA) based on Doppler assessment of coronary reserve
(CR) was carried out in 73 patients with cardiac pain syndrome (mean age 48+/-7
y... |
26,430 | [Heart failure and imbalance of chemical elements in myocardium of patients with
ishemic heart disease]. | Tissue content of chemical elements indirectly characterizes some metabolic
processes. We have analyzed content of chemical elements in left and right
ventricular myocardium of patients with ischemic heart disease with progressing
heart failure and have shown that during development and progression of heart
failure... |
26,431 | [Prognostic value of diastolic dysfunction for sudden cardiac death of patients
after myocardial infarction]. | We studied prognostic value of left ventricular (LV) diastolic dysfunction (DD)
in relation to sudden cardiac death (SCD) after myocardial infarction (MI). We
examined 603 patients in acute period of MI (including 551 with preserved LV
systolic function and DD). Duration of follow-up was 1-7 years. According to
dat... |
26,432 | [Possibilities of a preparation omega-3 polyunsaturated fatty acids in the
treatment of patients with ventricular arrhythmias and myocardial infarction]. | The aim was to study the effectiveness of prescription medication containing 90%
omega-3 polyunsaturated fatty acids for 6 months on ventricular arrhythmias in
patients with myocardial infarction less than a year ago. The study involved 56
patients with ventricular extrasystoles, from 500 to 1000 per day. Divided in... |
26,433 | [Predictive value C-reactive protein assessment level in women with arterial
hypertension]. | Classic modifiable cardiovascular risk factors, such as blood pressure and
dyslipidaemia are incorporated into clinical practice to estimate the 10-year
risk of fatal cardiovascular disease (CVD): the SCORE project. To improve CVD
risk estimation in women we compared predictive value of two models: risk chart
based... |
26,434 | [Alternative therapy with ivabradine in patients with functional class III
chronic heart failure]. | Aim of the study - to determine efficacy of therapy with the use of ivabradine
in patients with functional class (FC) III chronic heart failure (CHF) on the
basis of assessment of its action on regulatory adaptive status (RAS). We
included into the study 100 patients with FC III CHF at the background of
ischemic he... |
26,435 | [Special characteristics of chronotropic reaction to physical exercise in
patients with systolic heart failure and obstructive sleep apnea syndrome]. | In order to study special characteristics of chronotropic reaction to physical
exercise on veloergometer in the presence of obstructive sleep apnea (OSA) we
examined 84 patients with manifestations of chronic systolic heart failure (HF).
Chronotropic insufficiency was found in 88% of patients predominantly in
combi... |
26,436 | [Clinical value of insulin resistance in fasting normoglycemia]. | Aim of the study was to clarify the question of the presence of manifestations
of insulin resistance (IR) in fasting normoglycemia and to assess their
association with risk of development and presence of clinically overt
cardiovascular diseases (CVD) caused by atherosclerosis. We included into this
study 1127 men a... |
26,437 | [Noninvasive diagnosis of acute cellular rejection of transplanted heart]. | Endomyocardial biopsy remains the gold standard of diagnosis of acute cellular
rejection after heart transplantation. However, routine biopsies are of major
inconvenience to patients and are also risky and costly. In the present research
we considered possibility of non-invasive diagnosis of acute cellular rejection... |
26,438 | [Prevalence and clinical significance of multifocal atherosclerosis in patients
with ischemic heart disease]. | This review is devoted to the problem of detection of multifocal atherosclerosis
(MFA) in patients with acute and chronic forms of ischemic heart disease (IHD).
According to different sources rate of detection of MFA varies between 13.5 and
94%. According to register study conducted in the Kemerovo cardiological cen... |
26,439 | [Diagnosis and options for reconstructive heart valve surgery in the Marfan
syndrome]. | Marfan syndrome is a disorder of the connective tissue that is inherited in an
autosomal-dominant fashion and that is caused by mutations in the gene coding
for fibrillin-1, FBN1. Although complications of the syndrome may involve the
eye, the lung and the skeleton, the high mortality of untreated cases results
alm... |
26,440 | [Diagnosis and effective surgical treatment of constrictive pericarditis]. | Constrictive pericarditis is a rare and severe disease. Timely and correct
differential diagnosis of this pathology facilitates choice of necessary tactics
of treatment and thus improve prognosis and quality of life. In this paper we
present clinical case report of a patient with constrictive pericarditis. The
dise... |
26,441 | [Association of a polymorphic marker Trp719Arg of KIF6 gene with effects of
atorvastatin and simvastatin in patients with early ischemic heart disease]. | Action of statins is characterized by pronounced variability what is caused by
effects of a multitude of factors. Main of these factors appears to be genetic
peculiarity of patients. We studied influence of polymorphic marker Trp719Arg of
KIF6 gene on lipid and nonlipid effects of atorvastatin and simvastatin. The
... |
26,442 | [Effectiveness of early invasive strategy of treatment of angina of new onset]. | Aim of the study was to assess effectiveness of early invasive strategy of
treatment of angina of new onset (ANO). We conducted comparative assessment on
invasive and noninvasive risk estimation in 106 patients admitted to
N.V.Sklifosofsky Institute of Urgent Aid in 2003-2007. Percutaneous coronary
interventions (P... |
26,443 | [The role of micro-RNA/143/145 in evolution of intra-stent restenosis]. | The mechanisms of neointima formation and hyperplasia in restenosis remain
non-elucidated yet. Because micro-ribonucleic acids/143/145(micro-RNA/143 and
micro-RNA/145) participate in the regulation and sustaining of the genotype of
mature vascular myocytes we have measured their expression in tissue content of
rest... |
26,444 | [Clinico-economical aspects of application of trimetazidine MB in patients with
chronic heart failure and cardiac rhythm disturbances]. | AIM: To study clinical and pharmacoeconomical aspects of trimetazidine MD as a
component of complex therapy of chronic heart failure (CHF) in patients with
cardiac rhythm disturbances.
MATERIAL AND METHODS: In 82 patients (67 men, 15 women, mean age 62.2+/-7.3
years) with II-III functional class (FC) of CHF we studi... |
26,445 | [Parameters of central hemodynamics in patients with typical atrial flutter
before and after radiofrequency catheter ablation]. | We present here results of dynamic assessment of morphofunctional state of the
myocardium by the method of transthoracic echocardiography (EchoCG) in patients
with paroxysmal and chronic forms of typical atrial flutter (AF) before and
during one year after radiofrequency catheter ablation (RFA) of cavo-tricuspid
is... |
26,446 | [Effect of tests with dosed physical load on sinus node function and
repolarization in children with hereditary long QT syndrome]. | The study is devoted to assessment of effect of physical effort of sinus rhythm
rate and the state of the process of repolarization in children with 1 and 2
molecular-genetic variants of the long QT syndrome (LQT). We have shown that
LQT1 is characterized by inadequate increment of heart rate (HR) and substantial
i... |
26,447 | [Antitachycardia and resynchronization devices in the treatment of heart failure
and prevention of sudden death]. | According to the modern ideas of the heart failure pathogenesis the noticeable
contribution introduces ventricular dissynchrony which essence consists of the
electrical and mechanical dissociation of different segments of the myocardium.
In recent years the new method of cardiac resynchronization therapy has been
w... |
26,448 | [Cardioneurological aspects of antiplatelet therapy in secondary prevention of
cardiovascular diseases]. | The paper reflects contemporary views of the role of antiplatelet therapy in
secondary prevention of cardiovascular diseases in patients with coronary heart
disease and ischemic stroke. On the basis of evidence based medicine analytical
characteristics of all antiplatelet drugs subjected to clinical trials in the
w... |
26,449 | [Cardiac resynchronization therapy in patients with narrow QRS]. | Conduction delay affecting 30-50% of patients with NYHA class III-IV heart
failure (HF) mainly results from left bundle branch block and leads to
deterioration of cardiac contractility through intra- and interventricular
dyssynchrony. Cardiac resynchronization therapy (CRT) has class I recommendation
for the treatm... |
26,450 | [Value of the spectral analysis of radiofrequency intravascular ultrasound data
in the evaluation of nonsignificant coronary lesions in chronic CHD patients]. | Plaque complication depends on its composition and phenotype rather than on the
degree of stenosis. Plaque rupture predominantly occurs in areas with large
lipid core rich in cholesterol and thin fibrous cap. Features of unstable
atheromas are mostly described in patients with acute coronary syndromes (ACS).
The ai... |
26,451 | [High lipoprotein(a) in children of patients with premature coronary artery
disease: relation to own and parental factors]. | AIM: To elucidate associations between high level of lipoprotein(a) [Lp(a)] in
children of persons with premature (onset <55 years, men; <60 years, women)
coronary heart disease (PCHD) with own and parental characteristics.
MATERIAL AND METHODS: We surveyed 133 families: probands (n=122, 80.7% men) with
PCHD, spouse... |
26,452 | [Resting heart rate and one year mortality association in patients with coronary
heart disease]. | Heart rate is one of widely investigated new risk factors for the progression of
coronary heart disease. Aim of this study was to assess association between
admission resting heart rate (HR) and one-year survival in patients with
coronary heart disease in dependence on gender, age and clinical expression of
coronar... |
26,453 | [Myocardial revascularization in correction of electrical instability of the
heart in patients with postinfarction cardiosclerosis]. | We have assessed parameters of myocardial electrical instability in patients
with postinfarction atherosclerosis before and in one year after coronary bypass
surgery. Inclusion criteria were history of myocardial infarction, surgical
myocardial revascularization between 1 and 2 years before; stable course of
corona... |
26,454 | [The PATRIARCH study: effect of passive training on long term treatment results
with myocardial infarction]. | In order to study long term results of passive training sessions in myocardial
infarction in older patients with the use of electromyostimulation (EMS) of
skeletal muscles (the PATRIARCH Study) we examined 94 patients with acute
myocardial infarction (IM) older than 60 years. Among patients subjected to EMS
trainin... |
26,455 | [Polymorphism Gly460Trp of alpha-adducin gene and predisposition to essential
hypertension. The role of gene-environment interactions in the development of
the disease in Russian population]. | In this study we for the first time in Russian population elucidated association
between G460W polymorphism of -adducin gene (ADD1) and risk of development of
hypertensive disease (HD). DNA samples from 205 patients with HD and 207 healthy
nonrelated individuals of Russian nationality were genotyped for G460W
polym... |
26,456 | [The role of hypotension as a factor of unfavorable prognosis in patients with
chronic heart failure]. | Despite obvious achievements during last decades in studies of pathogenesis and
search for effective ways of treatment of chronic heart failure (CHF) it remains
one of most severe and prognostically unfavorable diseases of the cardiovascular
system. Thereby determination of predictors of death and detection of high ... |
26,457 | [Detection of risk factors and early manifestations of cardiovascular diseases
during ambulatory examination of working age persons]. | We have studied prevalence of risk factors (RF) of cardiovascular diseases (CVD)
recorded for statistical purposes in subjects of able bodied age during 10 year
period of observation in a policlinic as well as prevalence of early and/or
oligosymptomatic CVD manifestations in 11762 subjects of working age with RF of ... |
26,458 | [Risk and benefit of oral anticoagulants in atrial fibrillation]. | Thromboembolism is the main cause of death and disability of patients with
atrial fibrillation. Indirect anticoagulants are effective means of primary and
secondary prevention of thromboembolic complications. However in a number of
patients risk associated with therapy with indirect anticoagulants might exceed
pote... |
26,459 | [Pregnancy in women with heart defects: outlook on the problem]. | Modern approach to management of pregnancy and delivery in women with heart
defects is presented in this paper. The 3-level system of observation of this
contingent of patients is based on stratification of risk of development of
cardiological complications which allows to form an algorithm of physicians
actions, a... |
26,460 | [The use of multi-spiral computer tomography for early diagnosis of coronary
artery stenoses in patients with high risk of development ischemic heart
disease]. | Results of the study of clinico-diagnostic value of multispiral computed
tomography in patients with suspected ischemic heart disease (IHD) are described
in this paper. We have used 64-slice spiral computer tomography in examination
of 49 patients with high IHD risk referred to the cardiological hospital for IHD
ex... |
26,461 | [Early and postponed percutaneous coronary interventions in acute period of
myocardial infarction]. | Aim of the study was elaboration of indications to the application of postponed
percutaneous coronary interventions (PCI) in acute period of myocardial
Infarction (Ml) in patients without prior thrombolytic therapy. We fulfilled
comparative assessment of efficacy of 3 strategies of treatment of 810 patients
admitte... |
26,462 | [Acute coronary syndromes in hospitalized patients with diabetes. Data from the
RECORD registry]. | BACKGROUND: Diabetes is an acknowledged risk factor of unfavorable outcome in
patients with acute coronary syndromes (ACS). According to modern guidelines
patients with ACS and diabetes should be treated more aggressively than patients
of lower risk. However systematic data on treatment of ACS patients with
diabete... |
26,463 | [Three years experience of catheter treatment of patients with acute coronary
syndrome in conditions of 24-hour work of endovascular service]. | In this work we have summarized 3-years experience of the treatment of acute
coronary syndrome with the use of endovascular methods and presented
organizational basis allowing to realize 24-hour work of the endovascular
service, and algorithm of examination and treatment of patients admitted with
diagnosis of acute... |
26,464 | [The study of hypotensive action of dinitrosyl-iron complex with glutathione
containing drug oxacom in healthy volunteers]. | On the basis of earlier executed studies of hypotensive effect of dinitrosyl
iron complexes (DNIC) with glutathione, the drug has been created in industrial
conditions named oxacom. Preliminary pharmacological studies of oxacom have not
revealed negative qualities. The drug has been now tested in 14 healthy men in
... |
26,465 | [Efficiency perindopril at patients with arterial hypertension and obesity]. | We gave perindopril (10 mg/day) for 24 weeks to 30 patients with arterial
hypertension and obesity and proved its ability to effectively lower arterial
pressure, exert cardio-, angio-, and nephro-protection, improve parameters of
lipid, carbohydrate and purine metabolisms in these patients. Moreover
perindopril in ... |
26,466 | [Estimation of antihypertension efficiency and use of fixed combination
perindopril+amlodipin by uncontrollable hypertension patients within the limits
of routine treatment]. | The results of observational investigation by prescription of the fixed
combination perindopril + amlodipin produced by to the uncontrollable
hypertension patients by the previous therapy are described in the given
article. In Kazan population 50 patients at the age of 32 to 92 with essential
hypertension having bl... |
26,467 | [Prevalence of distress and coronary behaviour in patients with atherosclerosis
of various localization]. | Prevalence of distressor personality traits and coronary behavioral type was
studied in 943 patients (774 men and 169 women) with clinical forms of
atherosclerosis of various localization. Intermediate behavioral type AB
prevailed (69.9%), while types A (25.3%) and B (4.8%) were less frequent.
Patients with type B ... |
26,468 | [Mitochondrial antioxidant SkQl decreases intensity of ventricular arrhythmias
caused by epinephrine]. | Preventive action of new antioxidant SkQ1 has been studied in rats on model of
cardiac arrhythmia caused by epinephrine. The SkQ1 substance was given in
dosages from 0.02 up to 20 moles/kg per os 2 weeks prior to experiment.
Intravenous bolus introduction of epinephrine (10 or 6 mkg/kg in different
experimental ser... |
26,469 | [Stratification of risk of cardiovascular complications in government employees
and results of 10-year prospective observation]. | We investigated prognostic value of the SCORE scale in working age government
employees with 3 or more risk factors (RF) of cardiovascular diseases (CVD) and
metabolic syndrome (MS, 2001 criteria) according to results of 10-year
prospective observation in a policlinic. The study comprised 268 practically
healthy me... |
26,470 | [Interdisciplinary problems of male health: point of view of a cardiologist]. | Demographic situation in male population of Russia is analyzed in this review.
The role of diseases of cardiovascular system and urogenital diseases including
sexual disorders and androgen deficiency state in lowering of quality and
duration of life of reproductive age men is shown. Modern outlook on metabolic
synd... |
26,471 | [Priorities of secondary prevention of ischemic heart disease in conditions of a
depressive region: preliminary results of the North Caucasian project]. | AIM OF THE STUDY: was detection of behavioral factors, main risk factors of
development of cardiovascular diseases (CVD), assessment of adequacy of their
management, as well as assessment of quality of life in a cohort of patients
with ischemic heart disease from three republics of the North Caucasian region.
METHOD... |
26,472 | [Six months results of the Russian independent registry of acute coronary
syndromes RECORD]. | In 6 months after inclusion into the Russian independent registry of patients
with acute coronary syndromes (ACS) RECORD fate of 43% of participants (n=340)
was elucidated by telephone contacts. After discharge after index
hospitalization there were 15 deaths (4.8%) and 15 novel myocardial infarctions
(MI) (4.8%). ... |
26,473 | [One-stage PCI of left main stenosis and infarct-related left main major
branches in STEMI patients]. | AIMS: to determine immediate and long-term results, safety and efficacy of
one-stage PCI of LMCA and infarct-related LAD or CxA in STEMI.
METHODS: 81 patients with STEMI treated with one-stage PCI of LMCA and
infarct-related LAD or CxA were included into the study. LAD was infarct-related
in 53 (65.4%) patients, cir... |
26,474 | [Level of nitrous oxide in peripheral blood serum in patients with various
severity of arterial hypertension]. | AIM: To elucidate the role of nitrous oxide (NO) in development of severe
primary arterial hypertension (AH) including malignant hypertension and
concomitant ischemic heart disease (IHD).
MATERIAL AND METHOD: Patients with diagnosis of primary 1-3 degree AH (n=62, 21
men, 41 women aged 39-87 years, mean age 63.7+/-2... |
26,475 | [The study of circulating endothelial precursor cells in patients with chronic
heart failure]. | We examined 41 patients with ischemic heart disease (n=26) and dilated
cardiomyopathy (DCM) (n=15). Control group comprised 15 practically healthy
subjects. We found no substantial differences in the presence of CD34+CD133- and
CD34+CD133-VEGFR-2+ cells in peripheral blood of patients with chronic heart
failure (CH... |
26,476 | [Possibilities of recanalization of chronic coronary occlusions with penetration
catheter <<Tornus>>]. | Percutaneous coronary interventions (PCI) for chronic total occlusions (CTO)
remain one of most difficult parts of interventional cardiology. Introduction of
novel devices and methods of recanalization of CTO have facilitated fulfillment
of these interventions and increased number of successful procedures. Howere a ... |
26,477 | [Tissue engineering of heart valves: new opportunities and challenges]. | Replacement of heart valves appears to be prevailing method of surgical
correction of end stage valvular heart defects. Main drawback of contemporary
artificial valves is lack of growth, potential for remodeling, and inclination
to degeneration. To overcome these limitations the modern science in the last
decade fo... |
26,478 | [Nephroprotection diabetes mellitus type 2: lessons from the ADVANCE trial]. | Based on the results of the ADVANCE study, the article considers the issues of
medication nephroprotection in patients with type 2 diabetes mellitus, including
patients with uncontrolled arterial hypertension. Potentials for use of fixed
combination of perindopril + indapmide, which provides therapeutic effect at al... |
26,479 | [Factors determining prognosis of patients with stable ischemic heart disease
(results of a five years prospective study)]. | Risk stratification seems to be very important in patients with stable coronary
artery disease (CAD). However, the prognostic scales are now available only for
the early risk assessment in patients with acute coronary syndromes and in
patients undergoing percutaneous coronary interventions. Aim of the study was to
... |
26,480 | [Efficacy of ivabradine in patients with stable angina and comorbid chronic
obstructive pulmonary disease]. | We investigated impact of ivabradine on exercise capacity and quality of life in
patients with stable angina and comorbid chronic obstructive pulmonary disease
during treatment with -blockers. Ivabradine with -blockers reduced heart rate,
increased exercise capacity and improved angina more effective than -blockers ... |
26,481 | [Assessment of psychological status of patients with effort angina]. | AIM: Assessment of psychological status including levels of anxiety and
depression as well as susceptibility to chronic stress of men and women with
ischemic heart disease (IHD) and effort angina.
MATERIAL AND METHODS: We included in this study 530 patients with IHD and
functional class I+/-III effort angina (300 me... |
26,482 | [Level of glycemia as a marker of prognosis in patients with myocardial
infarction with ST segment elevation]. | High mortality of patients with myocardial infarction (MI) determines pursuit of
novel markers of risk as well as predictors of development of unfavorable
outcome. The question of the role glycemia in development of cardiovascular
complications in patients with acute coronary syndrome remains open. Analysis of
in h... |
26,483 | [Combined low-dose antihypertensive therapy in pregnant women with hypertension
and preeclampsia]. | The effect of low-dose combination antihypertensive therapy in fixed form,
containing 2.5 mg of bisoprolol and 6.25 mg of hydrochlorothiazide, the clinical
condition, the daily profile of blood pressure, body adrenoreactivity structural
and functional parameters of the left ventricle in 28 pregnant women with
preec... |
26,484 | [Newly developed atrial fibrillation among patients under active observation by
an outpatient clinic]. | We carried out prospective cohort study of incidence of new cases of atrial
fibrillation (AF) in a sample of Moscow population (patients under observation
in our policlinic). Total incidence of AF between 2003 and 2009 was 7.7 per 1000
patient/years, it was higher among men than among women. Incidence of AF
progres... |
26,485 | [Two years experience of the use of a penetration catheter (Tornus)
recanalization during percutaneous coronary interventions on chronic total
occlusions]. | We included in this study 43 patients chronic total occlusions (CTO) subjected
percutaneous coronary interventions (PCI) with the use of penetration catheter
(Tornus) in 2009-2010. Penetration catheter was applied only in those cases when
it was not possible to introduce low profile coronary dilatation catheter into... |
26,486 | [Left main coronary artery stenosis and progression of coronary artery
atherosclerosis after angioplasty and stenting in patients directed to coronary
artery bypass surgery]. | Recent investigations demonstrated appearance of left main coronary artery
stenosis after PTCA. We performed a retrospective study of specific
characteristics of development of coronary lesions after percutaneous coronary
interventions (PCI) in patients subjected to coronary artery bypass grafting
(CABG) because of... |
26,487 | [Long-term results of vascular surgery of Lerish syndrome in patients with type
II diabetes Mellitus]. | We analyzed long-term results of vascular surgery in 199 patients with diabetes
and chronic limb ischemia. At the time of the study mean age of patients was
64.7+1.2 years. They all had severe course of disease. Results showed that in
the majority of patients good clinical effect after aorto-femoral
reconstructions... |
26,488 | [Comparative evaluation of antiplatelet efectiveness drugs of original and
reproduced enteric forms of acetylsalicylic acid (clinical study ICAR))]. | The purpose of the study was a comparative study of antiplatelet activity of
acetylsalicylic acid drugs, produced in gastro-resistant form trombopol 75 mg
and aspirin cardio 100 mg in patients with high risk of cardiovascular events.
Effect of trombopol 75 mg versus 100 mg aspirin cardio on platelet aggregation
in ... |
26,489 | [The pulse wave velocity and fatal events rate in hypertensive patients have
gone through acute coronary syndrome]. | There are several stratification scales of major cardiovascular events rate for
patients have gone through acute coronary syndrome (ACS). None of them is
perfect one. Arterial hypertension is included into some scales for post ACS
patients but the features of it and its impact on coronary artery disease after
ACS h... |
26,490 | [Factors associated with inhospital severe bleeding in noninvasively treated
patients with non ST elevation acute coronary syndrome]. | Risk factors of bleeding in acute coronary syndrome (ACS) were derived from data
of clinical trials and registers with high proportion of invasively treated
patients. Aim of this study was to elucidate factors associated with severe
bleeding in patients with non ST-elevation (NSTE) ACS treated in a noninvasive
hosp... |
26,491 | [Dynamics of changes of blood inflammatory-oxidative biomarkers in acute
coronary syndrome]. | Some inflammatory cytokines and parameters of low density lipoproteins (LDL)
oxidative modification were studied in blood of 250 acute coronary syndrome
(ACS) patients--Siberian inhabitants, men and women with myocardial infarction
(MI) or unstable angina on first, tenth and thirtieth days of disease. The
inflammat... |
26,492 | [Manifestations of painless myocardial ischemia in patients with chronic
obstructive pulmonary disease]. | Aim of the study was to investigate prevalence and special characteristics of
manifestations of painless myocardial ischemia (PMI) in patients with chronic
obstructive pulmonary disease (COPD) at exacerbation stage with various degree
of severity and to assess risk of cardiovascular events in this group of
patients... |
26,493 | [Effect of ivabradine on pulmonary hypertension in chronic obstructive pulmonary
disease]. | In order to assess effect of If-channel blocker ivabradine on severity of
pulmonary hypertension in chronic obstructive pulmonary disease (COPD) we
studied 60 patients with III-IV stage COPD. We divided these patients into 2
groups with similar clinical characteristics and therapy. Patients of one of
these groups r... |
26,494 | [Influence of new III class antiarrhythmic drug Niferidil (RG-2) on
bioelectrical activity of rat pulmonary veins myocardium]. | Myocardial cells in pulmonary veins are thought to play a major role in the
initiation and maintenance of atrial arrhythmias, including atrial fibrillation.
In experiments on rat pulmonary veins, antiarrhythmic drug niferidil (RG-2)
produced increase of APD90% and functional refractory period and decrease of
action... |
26,495 | [Development of main disturbances of hemostasis in patients with obesity]. | According to current views obesity especially with increased amount of visceral
fat is characterized by prothrombogenic changes of hemostasis and fibrinolysis.
This combined with insulin resistance, compensatory hyperinsulinemia,
disturbances of carbohydrate metabolism, atherogenic dyslipidemia and
hypertension sub... |
26,496 | [Assessment of characteristics of myocardial deformation in healthy subjects of
various age groups by the X-STRAIN echocardiography]. | Aim of the study was to master XStrain software and to obtain values of left
ventricular (LV) myocardial velocity, longitudinal, circumferential, radial
strain, and strain rate in a population of healthy subjects from various age
groups. Sixty healthy volunteers were divided into 2 groups: aged 19-30 years (n
= 35,... |
26,497 | [The use of computer pulse oximetry monitoring for screening of sleep apnea in
patients of a hospital cardiology department]. | In order to assess the overall prevalence of sleep apnea of obstructive and
central origin in of patients hospital cardiology department we performed
continuous pulse oximetry monitoring during sleep in all patients admitted over
2 months. Of the 139 patients reliable results were obtained in 125 (89.9%). In
72% of... |
26,498 | [Painless myocardial ischemia in patient with extensive constrictive
atherosclerosis of coronary arteries]. | We describe in this article a clinical case of a patient with arterial
hypertension, painless myocardial ischemia and extensive constrictive
atherosclerosis of coronary arteries. Coronary heart disease (painless ischemia)
was suspected basing on results of transesophageal electrostimulation coupled
with stress echo... |
26,499 | [Prognostic value of markers of inflammation in patients with stable ischemic
heart disease after implantation of stents with drug covering at the background
of long-term therapy with statins (inhospital period)]. | The objective of this study was to examine the prognostic value of C-reactive
protein, erythrocyte sedimentation rate (ESR), white blood count, phospholipase
A2 in patients with stable ischemic disease on long-term statin therapy
undergoing percutaneous coronary intervention (PCI) with drug-eluting stent
implantati... |
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