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26,700 | [Prognostic value of left bundle brunch block in patients with acute coronary
syndrome]. | AIM: to assess rognostic value of ECG signs of left bundle brunch block (LBBB)
using database of registries of acute coronary syndromes (ACS) RECORD 1
(2007-2008) and 2 (2009-2011).
MATERIAL AND METHODS: Total number of included patients was 2452, 2321 patients
(94.9%) had no signs of LBBB, for 5 patients (0.2%) the... |
26,701 | [Chronic heart failure in patients with arterial hypertension and ischemic heart
desease: age and gender characteristics]. | AIM: to study prevalence of chronic heart failure (CHF) among patients with
arterial hypertension (AH) and ischemic heart disease (IHD), and specific
features of CHF in patients with different sex and age.
MATERIAL AND METHODS: We carried out retrospective analysis of CHF prevalence in
2048 patients with AH and/or I... |
26,702 | [Assessment of results of transesophageal echocardiography in patients with
atrial flutter]. | We performed 89 transesophageal electric cardiac stimulation procedures (TEECS)
in order to restore sinus rhythm in 75 (84.3%) men and 14 (15.7%) women with
type I atrial flutter (AF) due to coronary heart disease (n=59, 66.3%) and
cardiosclerosis after myocarditis (n=30, 33.7%). Before cardioversion all
patients u... |
26,703 | [Arterial stiffness in patients with chronic obstructive lung disease in the
presence and absence of ischemic heart disease]. | Aim of the study was assessment of arterial stiffness in patients with chronic
obstructive lung disease (COPD) with or without ischemic heart disease (IHD). We
included in this open study 130 COPD patients older than 40 years (mean age
60.2+/-8.3 years). Patients with clinical signs of exacerbation of other severe
... |
26,704 | [Analysis of approaches to assessment of persistent loss of capacity to work in
patients who had undergone coronary bypass surgery]. | Aim of the study was to assess factors influencing decisions about persistent
disability of patients after coronary bypass surgery (CBS). By method of
continuous sampling (registry study) we examined 427 working age patients who
had undergone CBS. Although surgical treatment was effective rehabilitating
factor most... |
26,705 | [The differences between the guidelines of the European Society of Cardiology
and the American College of Cardiology/ American Heart Association for oral
P2Y12 inhibitor therapy in the management of patients with acute coronary
syndromes]. | The analysis of the evidence that formed the basis for the current guidelines of
the European Society of Cardiology (ESC) on oral therapy by antithrombotic drugs
for acute coronary syndromes (ACS), and a comparison with the U.S. guidelines.
The ESC guidelines, published during 2011-2012, declared the superiority of ... |
26,706 | [Comorbidity in cardiac pathology: clinical-organizational and epidemiological
problems]. | Scientific (analytical) approach directs researcher to the study of nosology in
isolated native view. The phenomenon under consideration- comorbidity becomes
significant and to a substantial degree is able to affect all aspects of the
process of medical care. This is shown in this review along such directions as
fr... |
26,707 | [Comparison of data from registries of acute coronary syndromes RECORD and
RECORD-2: management of patients and its results in noninvasive hospitals]. | Positive changes are declared to occur during recent years in management of
hospitalized patients with acute coronary syndromes (ACS) in Russia. Most of
these changes are related to availability of invasive treatment. But
considerable portion of patients (pts) are still treated in hospitals without
facilities for i... |
26,708 | [The role of multifocal atherosclerosis in realization of new cardiovascular
complications during one year after non ST-elevation acute coronary syndrome]. | STUDY AIM: to assess prognostic value of multifocal atherosclerosis (MFA)
relative to risk of new cardiovascular catastrophes in patients with non ST
elevation acute coronary syndrome (NSTEACS) during one year follow-up.
MATERIAL AND METHODS: atients with NSTEACS (n=266) subjected to coronary
angiography and color d... |
26,709 | [Prophylactic use of VFS in patients with coronary artery disease in the
perioperative coronary artery bypass grafting]. | Tachyarrhythmias (TA) - dangerous postoperative complications of coronary artery
bypass grafting, threatening the lives of patients and found, according to
different authors, in 13-40% of cases. VFS - an antiarrhythmic drug that belongs
to a class 1C, is effective in the treatment and prevention of a variety of
car... |
26,710 | [Variants of remodeling of left ventricular myocardium in patients with arterial
hypertension and disturbances of carbohydrate metabolism]. | AIM: to study special characteristics of left ventricular (LV) myocardial
remodeling in patients with arterial hypertension (AH) and disturbances of
carbohydrate metabolism.
MATERIAL AND METHODS: We examined 241 patients with 1-2 degree AH and comparable
age and sex: 100 patients had type 2 diabetes mellitus (DM) (g... |
26,711 | [Oxygen supply to the brain in chronic disturbances of cerebral circulation in
patients with pathology of brachiocephalic arteries]. | We assessed objective parameters of cerebral oxygen supply in 469 patients with
multifocal atherosclerosis, hemodynamically significant lesions in
brachiocephalic arteries in dependence on degree of severity of vascular
cerebral insufficiency according to A.V. Pokrovsky classification of chronic
disturbances of cer... |
26,712 | [Clinical course and outcomes of myocardial infarction in women]. | We selected all case histories of patients living in the area served by the
Syktyvkar policlinic #3 and treated in Republican Cardiological Dispensary in
2003-2009 with diagnosis of myocardial infarction (MI). Data on survival of
patients after MI (mean duration of follow-up 4.6 years) was derived from
information ... |
26,713 | [The use of implantable devices for long-term monitoring of cardiac rhythm after
surgical treatment of atrial fibrillation in patients with ischemic heart
disease]. | We present in this paper experience of the use of implantable devices for
long-term monitoring of cardiac rhythm after one stage operation of coronary
artery bypass grafting (CABG) and radiofrequency ablation of atrial fibrillation
(AF) source and results of a prospective randomized study, in which we included
pati... |
26,714 | [Effect of an educational program on effectiveness and safety of anticoagulant
therapy in patients with prostheses of cardiac valves]. | We analyzed effectiveness and safety of anticoagulant therapy in patients with
prostheses of cardiac valves at the background of educational program and
without special training. We revealed positive effect of educational program
during participation in which in 80 cases (67.8%) patients determined
international no... |
26,715 | [Informativeness of genetic factors for optimization of personalized therapy
with clopidogrel]. | We studied occurrence of allele variants *1, *2, *3, and *17 of CYP2C19 gene and
polymorphic variants of ABCB1 gene in clopidogrel treated patients from West
Siberian and Far Eastern regions and determined contribution of these
polymorphisms to laboratory efficacy of clopidogrel. In dependence on magnitude
of chang... |
26,716 | [Successful treatment of bradyarrhythmia associated with obstructive sleep apnea
syndrome by continuous positive airway pressure]. | Obstructive Sleep Apnea Syndrome (OSAS) is an additional independent factor of
growth of cardiovascular mortality. Special role disturbances of respiration
during sleep play in development of nocturnal cardiac arrhythmias. Approaches to
correction of OSAS associated nocturnal bradyarrhythmias have substantially
cha... |
26,717 | [Influence of intensive hypolipidemic therapy on blood concentration of
lipoprotein-associated phospholipase A2 in patients with ischemic heart
disease]. | AIM: To assess the impact of combined treatment with simvastatin and ezetimibe
or treatment with simvastatin only on lipoprotein-associated phospholipase A2 in
patients with ischemic heart disease.
METHODS: One hundred patients with angiographically documented coronary
atherosclerosis took part in the investigation.... |
26,718 | [Erythrophagocytosis: a new diagnostic marker of immunologic myocardial damage
in ischemic heart disease]. | Using data of epidemiological and clinical examination of women of reproductive
and menopausal age we studied the processes of erythrophagocytosis (EF) in 46
women with ischemic heart disease (IHD) aged 20-59 years in comparison with a
group of healthy individuals. We found that women with IHD had almost 10-fold
in... |
26,719 | [Abnormal glucose tolerance and long-term prognosis in patients with acute
myocardial infarction]. | STUDY AIM: to assess clinical outcomes and cardiovascular events during
long-term follow-up after acute myocardial infarction (AMI) in patients (pts)
with newly detected abnormal glucose tolerance (AGT).
MATERIAL AND METHODS: Consecutive AMI pts (n=391, 24.3% with diabetes mellitus
[DM]) were enrolled in the study. ... |
26,720 | [Association between structure of atherosclerotic plaques in carotid arteries
and myocardial infarction]. | Aim of this study was to investigate association between structure of
atherosclerotic plaque (AP) in internal carotid artery and myocardial infarction
(MI), as well as to elucidate factors which may determine expansion of APs into
coronary arteries.
MATERIAL AND METHODS: We studied 655 patients (148 with MI and 507 ... |
26,721 | [Role of renal dysfunction and multifocal atherosclerosis in assessment of
prognosis of patients presenting with ST-elevation acute coronary syndrome]. | AIM: To assess incidence and severity of renal dysfunction as well as its
prognostic value in patients with ST elevation myocardial infarction (STEMI) and
multifocal atherosclerosis (MFA).
MATERIAL AND METHODS: We enrolled in this study 529 patients with STEMI in whom
we estimated creatinine clearance rate (eGFR) an... |
26,722 | [Magnesium orotate in treatment of chronic hypertension in pregnant women]. | We examined 150 pregnant women with essential hypertension (EHT), EHT and
connective tissue dysplasia (CTD), and healthy. Presence of CTD aggravated
clinical picture of EHT and was associated with pronounced cardialgic,
neurological, asthenic, vertebrogenic, visceral, and other syndromes. The use of
antihypertensiv... |
26,723 | [Heart rate turbulence and T-wave alternans as markers of risk of sudden cardiac
death in patients with hypertrophic cardiomyopathy]. | AIM: to study microvolt T-wave alternans (mTWA) and heart rate turbulence (HRT)
in patients with hypertrophic cardiomyopathy (HCMP).
MATERIAL AND METHODS: We examined 50 patients with HCMP: 15 (28%) with
obstructive form, 23 (46%) with major risk factors of sudden cardiac death
(SCD), 7 (14%) with left ventricular t... |
26,724 | [Variability of glycemia and ventricular rhythm disturbances in patients with
chronic heart failure and type 2 diabetes mellitus]. | Aim of this observational study was assessment of effect of variability of
glycemia on ventricular ectopic activity in patients with chronic heart failure
(CHF) and type 2 diabetes mellitus (n=80). According to study protocol 24-hour
Holter ECG monitoring was carried out at baseline, and after 3 and 6 months.
Measu... |
26,725 | [Histological and ultrastructural characteristics of myocardium in heart
failure]. | Endomyocardial biopsies performed in patients with various forms of
cardiomyopathies (CMP) and chronic myocarditis in the presence of heart failure
identified changes indicative of reduction of functioning cardiomyocytes (CMC)
at the account of their destruction, dedifferentiation and inefficient
hypertrophy". Ener... |
26,726 | [Hybrid revascularization: a combined approach to multivessel coronary artery
lesions]. | Analysis of effectiveness and feasibility of hybrid approach to multivessel
coronary artery disease and problems of interaction between cardiac surgeons and
interventional cardiologists in deciding on the choice of revascularization
method is performed in the article. Hybrid approach to multivessel disease
defined ... |
26,727 | [Quality of life of patients after coronary bypass surgery: effect of age and
personality type D]. | AIM: To study effect of age and presence of personality type D on quality of
life (QL) of patients in one year after coronary bypass surgery (CBS).
MATERIAL AND METHODS: Assessment of QL before and after surgery was carried out
in 408 patients. Two groups were formed: patients younger than 60 years (n=233)
and older... |
26,728 | [The diagnostic efficiency of the methods of separate and combined registration
of oronasal airflow and pulse oximetry for detection of the obstructive sleep
apnea/hypopnea syndrome]. | The diagnostic efficiency of the methods of separate and combined registration
of oronasal airflow and pulse oximetry in order to identify the obstructive
sleep apnea/hypopnea syndrome (OSAHS) is studied in this work. Patients with
cardiovascular diseases with complaints on sleep disorders were included in the
stud... |
26,729 | [Cardioprotective effect of remote postconditioning: mechanisms and possibility
of clinical application]. | Experimental data indicate that postconditioning at distance is an effective
method of cardiac protection against reperfusion injury. Remote postconditioning
prevents reperfusion necrosis and apoptosis of cardiomyocytes, decreases
probability of postinfarction remodeling of the heart. Cardioprotective effect
of rem... |
26,730 | [Efficacy of percutaneous coronary intervention in patients with ST elevation
myocardial infarction and impaired glucose tolerance or diabetes mellitus]. | PURPOSE: To assess the role of percutaneous coronary intervention (PCI) for
in-hospital and one-year prognosis of ST elevation (STE) myocardial infarction
(MI) patients with impaired glucose tolerance (IGT) or type 2 diabetes mellitus
(T2DM).
MATERIAL AND METHODS: This registry study included 601 STEMI patients admi... |
26,731 | [Efficiency of meldonium in the complex therapy of acute coronary syndrome]. | We examined 140 patients (mean age 54.8±3.1 years) with ST elevation acute
coronary syndrome resulting in Q-wave myocardial infarction of the left
ventricle. From the first hours complex therapy of these patients comprised
meldonium (1 g/day intravenously for 2 weeks then orally until 1.5 months).
Therapy with meld... |
26,732 | [Effect of combination antihypertensive therapy on circadian blood pressure and
metabolic parameters in patients with type 2 diabetes mellitus]. | AIM: To assess effect of combined antihypertensive therapy with lisinopril and
amlodipine on circadian blood pressure (BP), insulin resistance (IR),
carbohydrate and lipid metabolism in patients with arterial hypertension (AH)
and type 2 diabetes mellitus (DM).
MATERIAL AND METHODS: Combination of amlodipine (6.0±0.... |
26,733 | [Direct comparison of endothelial and metabolic effects of perindopril
combination with indapamide retard or hydrochlorothiazide]. | OBJECTIVE: Our aim was to compare changes of vascular and metabolic parameters
in patients with essential hypertension on treatment with combination of
perindopril with either indapamide retard or hydrochlorothiazide.
METHODS: The study involved 40 patients who were randomly assigned to
perindopril 5-10 mg/day in co... |
26,734 | [Test with torasemide in the differential diagnosis of dyspnea in patients with
cardiovascular diseases]. | We included into this study 21 patients with a cardiovascular disease and effort
dyspnea of at least one month duration. In accordance with result of tissue
Doppler echocardiography all patients were divided in 2 groups: 14 patients with
confirmed chronic heart failure (CHF) and 7 patients without CHF. All patients ... |
26,735 | [Correction of sinus rate by inhibitors of If-channels in patients with acute
decompensated heart failure]. | The aim of the study was to assess heart rate reduction for a acute
decompensated heart failure in patients with reduced left ventricular systolic
function and in patients with heart failure without significant reduction in
ejection fraction. Were examined 79 patients with an ejection fraction less than
40%. 38 of ... |
26,736 | [Invasive methods of detection of unstable atherosclerotic plaques in coronary
arteries]. | In most cases direct cause of acute coronary syndrome and sudden death is an
intracoronary thrombus formed on a surface of unstable atherosclerotic plaque
(UAP). The following are main characteristics of UAP: active inflammation; large
lipid rich nucleus occupying a 40% of plaque volume; thin (< 65 mm) fibrous cap; ... |
26,737 | [Atrial fibrillation as consequence and cause of structural changes of atria]. | Changes of atrial structure and function are the contributors of atrial
fibrillation clinical course, complications and treatment effectiveness. Effects
of inflammation and mechanical stretch on atrial structural remodeling leading
to atrial fibrillation are reviewed in the article. Contemporary invasive and
non-in... |
26,738 | [ATLANTIC trial and feasibility of early administration of ticagrelor in
myocardial infarction]. | The ATLANTIC trial compared effects of initiation of ticagrelor at the
prehospital (ambulance) or hospital (in the catheterization laboratory) stage of
treatment of patients with ST-segment elevation myocardial infarction.
Initiation of therapy with ticagrelor at prehospital stage short before
percutaneous coronary... |
26,739 | [Treatment of hypertensive emergencies and malignant hypertension: the
possibility of using urapidil]. | The review considers the possibility of using parenteral urapidil for treatment
of hypertensive crises. The drug having a dual mechanism of action and
properties of combining α-blocker and a centrally acting drug, has a high
efficiency, comparable to that of the other groups of drugs, and a good
tolerability. In a ... |
26,740 | [Secondary prevention in the clinical management of patients with cardiovascular
diseases. Core components, standards and outcome measures for referral and
delivery]. | Despite major improvements in diagnostics and interventional therapies,
cardiovascular diseases remain a major health care and socio-economic burden
both in western and developing countries, in which this burden is increasing in
close correlation to economic growth. Health authorities and the general
population hav... |
26,741 | [Novel class III antiarrhythmic agent niferidile: review of experimental and
clinical studies]. | This article reviews experimental and clinical studies of a novel antiarrhythmic
agent niferidile. Niferidile, a class III antiarrhythmic agent, blocks potassium
outward currents, prolongs repolarization and refractory periods predominantly
in atria than in ventricles. Intravenous Niferidile was efficient for
inter... |
26,742 | [Efficiency and safety of allapinin in short- and long-term treatment of
patients with normal heart and ventricular premature beats]. | Allapinin, class 1C antiarrhythmic drug, is highly effective in treatment of
patients with ventricular premature beats (VPB). The purpose of work was
retrospective assessment of efficacy and safety of allapinin in patients with
benign ventricular arrhythmias. 73 patients with VPB and no structural heart
disease wer... |
26,743 | [Level of mannose-binding lectin and phagocytic activity of leukocytes in
patients with acute coronary syndrome]. | Mannose-binding lectin (MBL) is a key component of innate immunity that starts
one of the ways of complement activation. Factors of neutrophil activation are
cell factors of innate and acquired immunity.
AIM: to study MBL levels and factors of neutrophil activation in patients with
acute coronary syndrome (ACS).
MET... |
26,744 | [Economic efficiency of renal denervation in patients with resistant
hypertension: results of Markov modeling]. | Aim of this study was to evaluate the cost-effectiveness of renal denervation
(RD) in resistant arterial hypertension (AH) in Russia. Modeling of Markov
conducted economic impact of RD on the Russian population of patients with
resistant hypertension in combination with optimal medical therapy (OMT)
compared with O... |
26,745 | [Efficacy and safety of bisoprololal in hypertensive patients with
cardiovascular disease and chronic obstructive pulmonary disease]. | Efficacy and safety of bisoprolol in hypertensive patients with cardiovascular
disease and chronic obstructive pulmonary disease. A comparative study on the
efficacy and safety of bisoprolol and sustained release metoprolol succinate in
patients with arterial hypertension (AH), cardiovascular disease (CVD) and
chro... |
26,746 | [Clinical profile and treatment of left main coronary artery disease in a
real-world practice]. | Aim of this study was to assess clinical profile, treatment and long-term
results in patients with left main coronary artery disease in a real-world
practice. 225 cases were analyzed. Long-term results were evaluated from 213
(97.7%) patients. Median follow-up period was 49 months. Fifty two (23.9%)
patients receiv... |
26,747 | [Revascularization or conservative strategy in patients with stable coronary
heart disease: a contemporary view]. | Choice between revascularization and conservative strategy in patients with
stable coronary heart disease (CHD) is an important clinical problem, especially
when the need for revascularization is not urged by severe ischemic symptoms.
Revascularization aimed to improve prognosis is most justified in patients
having... |
26,748 | [Visit-to-visit blood pressure variability: clinical and prognostic
significance]. | The phenomenon of variability of blood pressure (BP) was studied for a long
time, but recently it has received increased attention, with the focus shifted
from short-term BP variability, estimated at daily monitoring for clinical blood
pressure variability from visit to visit, which can be regarded as one of the
in... |
26,749 | [Electrocardiogram in acute period of myocardial infarction: from ischemia
severity and size of myocardial injury to clinical outcome]. | Electrocardiogram (ECG) registered in acute period of myocardial infarction (MI)
can be used not only for diagnostic purposes, but also for prediction of extent
of myocardial injury and assessment of prognosis. This review covers assessment
of acute ischemia in MI using Sclarovsky-Birnbaum classification and
Anders... |
26,750 | [Effect of 6-month therapy with perindopril A on structural-functional state of
arterial vascular bed in patients with chronic heart failure]. | In patients with chronic heart failure (CHF) endothelial dysfunction of large
vessels is an independent predictor of repeated hospitalizations because of CHF
aggravation and cardiac death.
OBJECTIVE: To evaluate the effect of perindopril A (5-10 mg/day) on endothelial
function of large vessels in patients with CHF.
... |
26,751 | [Risk factors of development of hypertension and metabolic abnormalities in
practically healthy]. | In a group of 492 apparently healthy working men (mean aged 55 years) we
measured body mass index (BMI), and assessed states of lipid, carbohydrate and
purine metabolism, morphological and functional state of cardiovascular system
(by transthoracic echocardiography), thickness of intima-media complex of common
caro... |
26,752 | [Prevalence and risk factors of extra-coronary artery disease in patients with
diabetes which confirmed atherosclerosis of coronary arteries]. | AIM: To assess prevalence and risk factors of extra-coronary artery disease
(peripheral artery (PA) disease (D) of lower extremities (LE), brachiocephalic
arterial (BCA) stenosis (S), renal arterial (RA) S in type 1 and 2 (T1 and T2)
diabetes (D) patients (P) with confirmed atherosclerosis of coronary arteries
(CA)... |
26,753 | [Predictors of survival after heart transplantation: role of pretransplantation
and posttransplantation factors]. | Objective of this study was to assess the impact of pre- and posttransplantation
factors on 12-month survival after orthotopic heart transplantation (OHT).
Annual survival after OHT was 79.2%. The following factors were significantly
negatively associated with annual survival: recipient's serum C-reactive protein
(... |
26,754 | [Brachial artery endothelial function in teenagers with obesity depending on
severity of clinical, trophological and metabolic disorders]. | We carried out complex examination of 68 adolescents aged 11-17 years with
primary obesity which in addition to assessment of clinical-anamnestic,
laboratory data and functional parameters of cardiovascular system included
registration of reaction of brachial artery endothelium to reactive hyperemia.
Vascular endot... |
26,755 | [Purine receptors and associated signaling systems in regulation of platelet
function]. | Purine receptors of platelets play key role in hemostasis and thrombogenesis and
they are used as targets for antiplatelet therapy. Platelets express three
subtypes of purine receptors--P2X1, P2Y1 and P2Y12. The expression, ligands and
sensitivity of purine receptors of platelets and their role in thrombogenesis
ar... |
26,756 | [Effect of design of standard metallic stents on neointimal hyperplasia and
restenosis]. | Coronary stents became an integral part of treatment of ischemic heart disease
(IHD). Number of percutaneous coronary interventions (PCI) in patients with IHD
in Russia constantly growing. At a certain stage of development of
interventional cardiology drug eluting stents (DES) were created and became
actively used.... |
26,757 | [Characteristics of coronary artery involvement and probability of appropriate
discharges of cardioverter-defibrillator implanted for primary prevention of
sudden cardiac death]. | PURPOSE: To assess characteristics of involvement of coronary vascular bed in
patients with ischemic heart disease and cardioverter defibrillator (CD)
implanted for primary prevention of sudden cardiac death (SCD) with and without
history of appropriate implantable (I) CD therapies.
MATERIAL AND METHODS: We examined... |
26,758 | [Blood viscosity in patients with ischemic heart disease]. | AIM: To elucidate relation of blood viscosity to development of a hypoxic state
of microcirculation in patients with ischemic heart disease (IHD).
MATERIAL AND METHODS: We examined 42 patients with postmyocardial infarction
cardiosclerosis and 30 healthy persons (control group). Measurements were made
by rotatory vi... |
26,759 | [Results of the Russian EKSPERT program: post-marketing supervision over
efficacy and influence of the preparation Ekvator on quality of life at
out-patients with arterial hypertension]. | Results of an open multicenter prospective postmarketing observational program
EKSPERT (post-marketing surveillance of the effectiveness and impact of the
EKVATOR treatment on quality of life in patients with arterial hypertension in
ambulatory practice). Observation of 10 000 patients conducted in 300 medical
cent... |
26,760 | [Renin-angiotensin-aldosterone system in hypertrophic cardiomyopathy]. | Keeping in mind an important role of renin-angiotensin aldosterone system (RAS)
in developing of cardiac remodeling and fibrosis, genetic polymorphisms coding
its components could have influence with clinical variants of the course.
Biomarkers could appear predictors of adverse. To examine the contribution of
the R... |
26,761 | [Degenerative aortic stenosis: prediction of poor prognosis by 2D left
ventricular longitudinal strain in non-operated patients]. | AIM: To investigate relationship between global longitudinal peak strain (GLPS)
of the left ventricle (LV) and clinical routine echocardiographic (ECHO) and
electrocardiographic (ECG) parameters in patients with non-operated aortic
stenosis (AS) of all degrees. Also we evaluated the prognostic value of GLPS in
pati... |
26,762 | [Clinical management of patients with abdominal aortic aneurysms combined with
coronary artery disease and multifocal atherosclerosis]. | We have analyzed clinical management of 137 patients with atherosclerotic
aneurysms of the abdominal aorta combined with coronary artery disease treated
during last 10 years in the First Cardiac Surgery Department (Surgery of the
Aorta and its Branches) of the Petrovsky National Research Center of Surgery.
All pati... |
26,763 | [Effect of psychosocial stress on the level of anxiety, depression and
behavioral risk factors of cardiovascular diseases in men]. | AIM: To elucidate peculiarities of risk factors (RF) of cardiovascular diseases
and frequency of arterial hypertension (AH) at place of work in men with various
level of psychosocial stress.
MATERIAL AND METHODS: We examined 224 men (and their assistants) aged 22-55
years. Examination included analysis of risk facto... |
26,764 | [Complex study of the rat heart at isoproterenol damage]. | Introduction of isoproterenol (an agonist of beta-adrenoreceptors) to rats is
one of the widespread experimental models of cardiac failure. It is caused by
damage of cardiomyocytes with the subsequent development of substitutive
fibrosis. The purpose of the given work was the complex characteristic of
cardiac funct... |
26,765 | [Lipoprotein-associated phospholipase A2 serum levels in patients from different
categories of cardiovascular risk]. | AIM: To compare levels of lipoprotein-associated phospholipase A2 (Lp-PLA2) in
blood serum of patients from different cardiovascular risk categories.
MATERIAL AND METHODS: Patients from Moscow prospective study database (n = 519)
were divided into 4 cardiovascular risk categories according to present clinical
recomm... |
26,766 | [Cardiovascular diseases and mannose-binding lectin]. | The role of innate immunity factors in the pathogens of ACS is not well studied,
although there is evidence in the literature about their impact on the course of
cardiovascular diseases. Mannose-binding lectin (MBL)--one of the key factors of
the humoral innate immune system that activates one of complement activati... |
26,767 | [Analysis of the effect of antihypertensive drugs on left ventricular
hypertrophy regression]. | In a review article reflects the leading role of combined treatment of blockers
of the renin-angiotensin-aldosterone system and dihydropyridine calcium
antagonists in reducing left ventricular mass. The advantages of fixed
combinations in the treatment of hypertensive patients, including those with
left ventricular... |
26,768 | [Dynamics of cardiovascular mortality among men and women in subjects of Russian
Federation (2002 to 2011)]. | OBJECTIVE: to study the dynamics of CVD mortality in men and women in the
Russian Federation (RF) for the period from 2002 to 2011.
METHODS: The study was performed on the basis of official statistics "Rosstat".
Results. In 2011 the average death rate from CVD for the regions of the Russian
Federation among men and ... |
26,769 | [Effect of cascade plasma filtration on spectrum of subfractions of low density
lipoproteins in blood plasma of patients with ischemic heart disease]. | We studied effect of cascade plasma filtration on subfractions of low density
lipoproteins (LDL) in 16 patients with ischemic heart disease (IHD) and
hyperlipidemias refractory to drug therapy. The procedure caused 37.6 ± 1.4%,
43.1 ± 2.5%, and 50.9 ± 1.4% lowering of total, low density lipoprotein
cholesterol, and... |
26,770 | [Natural dynamics of blood pressure, body mass index and lipid levels in the
elderly (the results of 17-year follow-up)]. | AIM: to study natural dynamics of mean levels of systolic and diastolic arterial
pressure (SAP, DAP), body mass index (BMI), total cholesterol (TC), high density
lipoprotein cholesterol (HDLC), and triglycerides (TG) in elderly people using
data of 17-year cohort prospective observation.
MATERIAL AND METHODS: Primar... |
26,771 | [Effects of coronary angioplasty on clinical status, perfusion myocardial
contractility in patients with ischemic chronic heart failure]. | Chronic heart failure (CHF) remains widespread and prognostically unfavorable
complication of various cardiovascular diseases. Most patients with CHF have
atherosclerosis of coronary arteries. Main method of treatment of this condition
is endovascular revascularization. In this study we conducted detailed analysis
... |
26,772 | [Idiopathic arrhythmias: possibilities of complex nosological diagnosis, and
differentiated treatment]. | AIM: of the study was to elucidate nosological nature of "idiopathic"
arrhythmias by means of complex clinical-morphological examination and to assess
efficacy of differentiated (including etiotropic and pathogenetic) treatment.
MATERIAL AND METHODS: We examined 190 patients (117 women, mean age 45.33 ±
14.84 years)... |
26,773 | [Approximation of mathematical scanning simulation data and clinical results f
radiofrequency ablation of perimitral atrial flutter. Condition of existence of
perimitral atrial flutter]. | AIM: 1) to create Perimitral Atrial Flutter (PMAFL) model and estimate
theoretical probability of elimination of perimital reetntry using left atrial
geometry two-dimensional mathematical modeling and ablative formatting; 2) to
compare clinical results of PMAFL ablation by means of mitral vs inferioseptal
isthmus a... |
26,774 | [Clinical experience of application mildronate at recovery treatment of patients
with displazia connecting fabric]. | In order to evaluate the effectiveness mildronate in rehabilitative treatment in
connective tissue dysplasia examined 240 patients (24,41 ± 7,62 years, 130 men).
All patients were treated with 5 ml of mildronate 10% intravenously for 10 days,
then 1 capsule (250 mg), 2 times per day for 4 months. The therapy showed ... |
26,775 | [Microvascular angina]. | Microvascular angina is a rather widely spread disease which is associated with
high rate of unfavorable outcomes and substantial economical cost of examination
and treatment. However problems of noninvasive diagnostics of the disease have
not been entirely solved as well as clear-cut algorithm of management has not... |
26,776 | [Telomeres and chronic heart failure]. | With age, a person's cardio-vascular system changes gradually formed at
different functional levels, which are the basis for the development of chronic
heart failure. While aging itself does not lead to chronic heart failure, it is
likely that age-related changes in the human body can accelerate the time onset
of s... |
26,777 | [Practical aspects of therapy with new oral anticoagulants in patients with
impaired renal function]. | The article deals with renal dysfunction, methods of assessment and monitoring
in patients receiving anticoagulant therapy. Due to the negative impact of renal
impairment on the incidence of thromboembolic and hemorrhagic complications in
patients with atrial fibrillation problem identifying renal failure and its
d... |
26,778 | [Modern tactics antihypertensive therapy: a place of Angiotensin converting
enzyme inhibitors]. | In a review article we presents an analysis of the new recommendations of the
European Society of hypertension (ESH) and the European Society of Cardiology
(ESC) on the management of arterial hypertension (2013). Main attention is paid
to the tactics of antihypertensive therapy and the choice of drugs in the
treatm... |
26,779 | [Adenosine triphosphate stress (99m)Tc-MIBI single-photon emission computed
tomography in the diagnosis Miocardial Iscemia in patients with Microvascular
Angina]. | PURPOSE: To assess diagnostic potential of (99m)Tc-MIBI-single-photon emission
computed tomography (SPECT) with intravenous adenosine triphosphate (ATP)
infusion in comparison with exercise stress (EX) SPECT in patients with
microvascular angina.
MATERIAL AND METHODS: Patients with angina, positive exercise test and... |
26,780 | [Special characteristics of progression of myocardial remodeling in patients
with various forms of unstable angina]. | AIM: To study special characteristics and prognostic value of cardiac remodeling
in patients with unstable angina (UA).
MATERIAL: Throughout 2 years we performed repetitive echocardiographic
examinations of 166 patients with Braunwald class IB and IIB-IIIB UA for
assessment of left ventricular (LV) structural-functi... |
26,781 | [Perspectives of application of evidence-based measures of blood pressure
control in patients with arterial hypertension]. | AIM: of the study was to assess advantages and disadvantages of existing
measures of adequacy blood pressure (BP) control and their appropriateness in
Russian population of patients with arterial hypertension (AH).
MATERIAL AND METHODS: Two indicators were studied with the help of American
College of Cardiology/Amer... |
26,782 | [Endothelial and metabolic effects of perindopril in patients with essential
hypertension]. | OBJECTIVE: To elucidate endothelial and metabolic effects of perindopril and
their interaction in patients with uncomplicated essential hypertension.
METHODS: The study involved 30 patients treated with perindopril (5-10 mg/day)
for 3 months. The following parameters were registered at baseline and at the
end of the... |
26,783 | [Uric acid and factors of cardiometabolic risk in adolescents with arterial
hypertension]. | AIM: To elucidate links of blood serum uric acid level (SUAL) with
cardiometabolic risk factors (CMR) in adolescent boys with arterial hypertension
(AH).
MATERIAL AND METHODS: We examined 261 adolescent boys (mean age 15.8+/-1.3
years) with primary AH. Examination included 24-hour blood pressure (BP)
monitoring, an... |
26,784 | [Cost-effectiveness of apixaban compared to other new oral anticoagulants in
patients with non-valvular atrial fibrillation]. | BACKGROUND: Atrial fibrillation is associated with development of thromboembolic
events. New oral anticoagulants (apixaban, rivaroxaban and dabigatran) are
recommended for antithrombotic therapy in patients with non-valvular atrial
fibrillation (NVAF) with moderate and high risk of stroke.
OBJECTIVES: The objective ... |
26,785 | [Using meldonium to improve the adaptation of patients with cardiovascular
disease to the effects of heat and correction of associated oxidative stress]. | Given that prolonged exposure to extreme climatic situations may play a role
independent of stress factors, influencing the course of the underlying disease,
the authors considered appropriate assessment of the effectiveness of additional
prophylactic administration of drugs that increase the body's resistance to
s... |
26,786 | [Cardioprotective capabilities of drug meldonium in secondary prevention after
percutaneous coronary intervention in patients with documented myocardial
ischemia]. | The purpose of research — analysis of capabilities in cytoprotective drug
mеldonium, in complex in the cardioprotective effect of secondary prevention
after percutaneous coronary intervention (PCI). Patients with stable coronary
heart disease (n=35 ) aged ≤65 years with incomplete revascularization at 6
months afte... |
26,787 | [Pharmacogenetic aspects of antiarrhythmic drug therapy]. | It is known for a long time that individuals vary widely in their responses to
therapy with different drugs. Variability in drug response may be due to
variability in the relationship between drug dose and concentrations of the drug
at target sites (pharmacokinetic variability). Another mechanism is that
individual... |
26,788 | [Tissue Doppler imaging and ultrasonic methods for evaluating myocardial
deformation in the diagnosis of hypertrophic cardiomyopathy]. | Hypertrophic cardiomyopathy (HCM) is a genetic cardiovascular disease caused by
mutations in genes that encode components of the sarcomere. Standard
echocardiography is not always capable to identify regional systolic dysfunction
of the left ventricle (LV), and to detect the disease on its preclinical stage.
Geneti... |
26,789 | [Antiplatelet therapy before coronary artery bypass surgery. Is the bridging
therapy possible?]. | The number of patients with coronary artery disease undergoing percutaneous
coronary interventions (PCI) with stenting is growing. Stenting is associated
with dual antiplatelet given until endothelization of stent. In some clinical
situations surgery is required, e.g. coronary bypass, before stent is
endothelized o... |
26,790 | [Assessment of clinical-instrumental, morphological data and expression of
coxsackie adenovirus receptor in patients with inflammatory cardiac pathology]. | In 22 patients with heart failure and/or ventricular arrhythmias presumably of
inflammatory etiology the results of clinical and instrumental investigation
were analyzed and compared to the endomyocardial biopsy data. In the subgroup of
patients with left bundle branch block (LBBB) we revealed features indicative of... |
26,791 | [Value of Fatty acids in formation of thrombotic status in patients with
ischemic heart disease]. | Interrelation between fatty acids and platelet aggregation has been a subject of
interest for cardiologists in the terms of thrombogenic status. In order to
study this problem we observed 42 patients with ischemic heart disease and 30
healthy persons. In patients we found elevation of arachidonic acid and lowering
... |
26,792 | [Hronic heart failure and concomitant diseases in elderly patients: anemia and
cardio-renal anemic syndrome]. | to assess impact of anemia on chronic heart failure (CHF) course in elderly
patients in primary care setting. Methods. We examined 164 outpatients (n=164)
aged 60-85 years with clinically stable CHF due to ischemic heart disease and
arterial hypertension. All patients underwent clinical, laboratorial evaluation,
EC... |
26,793 | [Functional state of right ventricular myocardium in patients with acute
pulmonary embolism before and after thrombolytic therapy]. | We present in this paper results of assessment of functional state of right
ventricular (RV) myocardium in 38 patients with acute pulmonary embolism (PE)
before and after endovascular recanalization of pulmonary arteries supplemented
with thrombolytic therapy. According to echocardiography data RV dysfunction was
d... |
26,794 | [Pulse wave velocity and pulse pressure in patients with arterial hypertension]. | The article is devoted to assessment of pulse pressure (PP) in female
postmenopausal patients and patients with arterial hypertension (AH) older than
55 years. It is shown that in postmenopausal women even aged 55 years or less PP
is one of most important parameters associated with target organ damage.
Conclusion a... |
26,795 | [Role of multidetector computed tomography and stress- echocardiography in
assessment of risk of cardiological complications of non-cardiac surgery]. | AIM: to compare results of coronary angiography with data of multi-slice
computed tomography (MSCT) - angiography, and analyze rate of detection of
hemodynamically significant coronary artery lesions during preoperative
examination of patients.
MATERIAL AND METHODS: We analyzed case histories of 92 patients (median ... |
26,796 | [Possible applications bisoprolol for heart rate control in young patients with
connective tissue dysplasia]. | To assess the efficacy and safety of bisoprolol to monitor heart rate (HR) in
young patients with connective tissue dysplasia (CTD) examined 58 patients (22,3
+ 3,47 years, 38 men). Bisoprolol drug was administered at an initial dose of
1.25 mg/day, with a further increase to 2.5 mg/day in 2 weeks, etc. to achieve
... |
26,797 | [Possibilities of primary prevention of stroke: elaboration of a population
level strategy]. | This review is devoted to principles of primary prevention of cerebral stroke.
Prevalence of stroke and its contribution to development of complications and
lethal outcomes is analyzed in detail. Main principles of prevention of stroke
are delineated and contemporary international guidelines on correction risk
fact... |
26,798 | [The role of modern echocardiography methods in diagnosis of pulmonary
hypertension]. | The review contains presentation of diagnostic possibilities of contemporary
echocardiographic techniques for investigation of structural functional state of
the right ventricle and various methods of estimation of pulmonary artery
pressure. Normative values of various parameters are adduced according to last
recom... |
26,799 | [Autoantibodies against lipoprotein(a) in patients with coronary heart disease]. | OBJECTIVE: Lipoprotein(a) - Lp(a) is an independent risk factor of
atherosclerosis and its complications. In spite of the long period of Lp(a)
research there is no complete understanding of its physiological role and
atherogenic action. The goal of this study was to investigate the presence in
human plasma of circu... |
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