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26,900 | [Cognitive impairment in postmenopausal women with arterial hypertension]. | The aim of the study was to assess relationship between organ damage and changes
of cognitive function in postmenopausal women with arterial hypertension during
3 years of follow-up. A total of 55 women (aged 69 ± 9,5 years) with stable
course of hypertension were included. During period of observation and treatment... |
26,901 | [Cardiotropic action of oxacom in experimental heart failure]. | Prolonged hypotensive effect of oxacom (dinitrosyl iron complexes with ligand
glutathione) has been well documented in animals and healthy volunteers, but
effect on the heart is not defined. In this work, the blood pressure (BP), and
the pressure in the left ventricle (LV) were recorded in rats. Intravenous bolus
i... |
26,902 | [Microvolt T-wave alternans in adolescent elite athletes]. | Microvolt T-wave alternans (MTA) is one of markers of electrical myocardial
instability.
STUDY AIM: To elucidate normal range of MTA parameters during bicycle exercise
test (ET) in adolescent elite athletes.
MATERIAL AND METHODS: We examined 500 athletes aged 9-18 (mean 16.1 ± 2.2) years
members of national teams of... |
26,903 | [The use of novel technologies for assessment of myocardial function in clinical
practice]. | Key factors defining the prognosis of patients with heart failure (HF) are
cardiac remodeling and myocardial contractility. New methods of visualization of
myocardial motion gave impulse to research in the area of heart physiology and
pathology. However in clinical practice these methods are still rarely used.
Eval... |
26,904 | [To the centennial of Norman Holter (1914-1983)]. | The article is devoted to the centennial of the founder of ambulatory ECG
monitoring Norman Jeffrey Holter (1914-1983). It contains brief history of the
scientist's family, and depiction of his own educational way from magister of
chemistry and physics to specialist in nuclear research. His activity during
World Wa... |
26,905 | [The role of markers of organ damage in patients with chronic heart failure]. | This review is devoted to the studies of the role of modern markers of
myocardial and renal damage (high sensitivity troponin T [hsTnT] and urinary
neutrophil gelatinase-associated lipocain [NGA/lipocalin-2] in patients with
chronic heart failure (CHF). It contains description of nature, mechanism of
synthesis, and... |
26,906 | [Novel algorithms in treatment of dyslipidemia: comparative analysis of new
American and European recommendations]. | This analytical review is devoted to analysis of discrepancies between new
American and European recommendations/Significance of level of cardiovascular
risk, taget levels of lipids, intensity of therapy, application of therapy with
statins and/or expedience of the use of other lipid lowering drugs. Main
difference... |
26,907 | [Transcatheter treatment of degenerative critical aortic valve stenosis in a
patient with severe heart failure and chronic lymphocytic leukemia]. | Surgical aortic valve replacement is the standard therapy for severe aortic
valve stenosis, however one third of patients are rejected because of high
surgical risk. Under medical treatment alone these patients have a very poor
prognosis with a high mortality rate. We present a case of 70-year-old male
patient with... |
26,908 | [Comparison of Atherosclerotic Lesions in Patients With Acute Myocardial
Infarction and Stable Angina Pectoris Using Intravascular Ultrasound]. | AIM: to compare noninfarct-related lesions in patients with acute myocardial
infarction (MI) with culprit and non-culprit lesions in patients with stable
angina pectoris (SAP) using intravascular ultrasound virtual histology
(VH-IVUS).
MATERIAL AND METHODS: Overall 70 patients were enrolled: 38 with ST elevation
(S... |
26,909 | [First Experience of Clinical Application of LCZ696 an AT1-angiotensin Receptors
and Neprilysin Inhibitor in Patients With Chronic Heart Failure and Reduced
Ejection Fraction]. | Simultaneous inhibition of the renin-angiotensin-aldosterone system and the
system of degradation of natriuretic peptides can potentially provide unique
therapeutic effects in patients with chronic heart failure (CHF) with reduced
ejection fraction (EF). Aim of this study was to assess tolerability of therapy
with ... |
26,910 | [Pleiotropic Effects of Rosuvastatin in Patients With High Cardiovascular Risk]. | hronic obstructive pulmonary disease (COPD) is the third leading cause of death
in the list of common causes of mortality after cardiovascular diseases. The
processes of atherogenesis and cardiovascular diseases are accelerated in
patients with COPD. The key mechanisms of COPD pathogenesis are oxidative
stress, dep... |
26,911 | [Comparative Assessment of Effects of Isosorbide Dinitrate,
Isosorbide-5-Mononitrate and Nicorandil on the Frequency of Angina Attacks and
Vasoregulating Endothelial Function in Patients With Ischemic Heart Disease]. | to compare effects of isosorbide dinitrate, isosorbide-5-mononitrate and
nicorandil on frequency of angina attacks and vasoregulating endothelial
function in patients with ischemic heart disease (IHD). MATERIAL AND METHODS. In
117 patients with stable II-III functional class angina we analyzed frequency of
angina a... |
26,912 | [Effect of Fixed Lercanidipine/Enalapril Combination on 24-Hour Blood Pressure
Proffie in Elderly Patients With Arterial Hypertension]. | We studied effect of therapy with fixed combination of lercanidipine and
enalapril on 24-hour blood pressure (BP) profile in 34 elderly patients (mean
age 76.4±5.2 years, 14 men, 20 women) with degree I hypertension. After clinical
examination patients were given lercanidipine/ enalapril combination (10/10
mg/day).... |
26,913 | [Biomarkers in Heart Failure: Apelin Level Is Not Associated With Presence and
Severity of the Disease]. | We tested possibility of the use of apelin-12 as a biomarker of chronic heart
failure (CHF). The study comprised 108 patients with I-IV functional class CHF
of various etiology (ischemic heart disease, dilation cardiomyopathy) and 40
healthy volunteers. Blood samples were taken at hospital admission before
prescrip... |
26,914 | [First Results of Analysis of Russian Part of the European Register on Cardiac
Rehabilitation EuroCaReD (European Cardiac Rehabilitation Database)]. | The joint European Registry of patients with cardiovascular diseases
participating in cardiac rehabilitation programs (European Cardiac
Rehabilitation Database, EuroCaReD) is conducted in collaboration between the
ESC and EACPR). It's main goals were to improve the routine use of cardiac
rehabilitation, to develop ... |
26,915 | [Assessment of Risk of Development of Diabetes Mellitus Among Physicians of
Therapeutic Proffle: Results of a Screening Study]. | AIM: to assess risk of development of diabetes mellitus (DM) and detection of
other metabolic derangements among physicians-internists.
MATERIAL AND METHODS: In an open clinical screening study participated 117 male
and 167 female physicians mostly cardiologists and internists from various
regions of Russia. All par... |
26,916 | [Efficacy and Safety of Rosuvastatin in Patients of Different Risk Groups of
Developing Cardiovascular Diseases]. | The purpose of the review - analysis of randomized clinical trials to evaluate
the efficacy and safety of rosuvastatin in respect of primary and secondary
prevention of cardiovascular events, as well as in patients with acute coronary
syndrome. As a primary pathogenetic therapy aimed at reducing the risk of
cardiov... |
26,917 | [ADVANCE-ON Trial; How to Achieve Maximum Reduction of Mortality in Patients
With Type 2 Diabetes]. | Of 10,261 patients with type 2 diabetes who survived to the end of a randomized
ADVANCE trial 83% were included in the ADVANCE-ON project for observation for 6
years. The difference in the level of blood pressure which had been achieved
during 4.5 years of within trial treatment with fixed perindopril/indapamide
co... |
26,918 | [The State of Hemostasis and Immune System in Patients With Acute Coronary
Syndrome Combined With Anxiety-Depressive Disorder]. | Anxiety-depressive disorders (DD) have a negative impact on the course and
prognosis of patients with ischemic heart disease, but the mechanisms of their
correlation are not studied enough. The purpose of this study was to elucidate
special characteristics of hemostasis and immune system in patients with acute
coro... |
26,919 | [Thiotriazoline in the Treatment of Stable Angina IIIII Functional Class]. | Trimetazidine is a metabolic agent of proven efficacy in improving myocardial
ischemia and angina. A comparative international multicenter randomized trial,
assessed anti-anginal anti ischemic efficacy and safety of Trimetazidine (60
mg/d) and Thiotriazoline (600 mg/d) in symptomatic patients with chronic
ischemic ... |
26,920 | [Effects of Meldonia in Early Postmyocardial Infarction Period]. | The aim of PMICS (Postmyocardial Infarction Cardiosclerosis) patients therapy
within the dispensary supervision is CCI (Chronic Cardio Insufficiency)
progression prevention, life quality improvement, hospitalization number
decrease and life prognosis improvement. Despite the developed approaches to the
given patien... |
26,921 | [Cardio-Nephroprotection the Most Important Goal of Antihypertensive Therapy in
Patients With Type 2 Diabetes]. | AIM: to study the opportunities for cardio and nephroprotection by 6-month
combined antihypertensive therapy with lisinopril and amlodipine in hypertensive
patients with diabetes mellitus (DM) type 2.
MATERIALS AND METHODS: 30 patients with arterial hypertension (AH) stage II-III,
chronic kidney disease (CKD) stages... |
26,922 | [Effect of L-Carnitine on QT Dispersion in Patients With Acute Coronary
Syndrome]. | to evaluate the impact of L-carnitine on the dispersion of the interval QT
(AQTc) in patients with acute coronary syndrome (ACS). In a prospective,
randomized, double-blind, placebo-controlled study included 58 patients with ACS
who have not had surgery (29 in group receiving L-carnitine, and 29 in the
placebo grou... |
26,923 | [Correlation of Endothelial Dysfunction With Course of Essential Arterial
Hypertension in Adolescence]. | AIM: to study laboratory parameters of endothelial dysfunction (ED) and their
correlation with risk factors (RF) of cardiovascular diseases at early stages of
essential arterial hypertension (AH) in adolescents.
MATERIAL AND METHODS: We examined 299 adolescents aged 12-18 years with EAH.
According to results of 24-h... |
26,924 | [Economic Evaluation of Riociguat in Patients with Inoperable or Residual
Chronic Thromboembolic Pulmonary Hypertension]. | OBJECTIVE: to undertake economic evaluation of riociguat in comparison with
standard practice of treating patients with inoperable or residual chronic
thromboembolic pulmonary hypertension (CTEPH) in Russian healthcare. METHODS.
Standard practice was revealed by means of peer interview. It comprised bosentan
monoth... |
26,925 | [Detection of Signs of Thrombus Formation in Patients With Typical Atrial
flutter]. | AIM: to assess rate of detection of markers of thrombi formation and to
determine whether transthoracic echocardiography data or clinical
characteristics predict severe left atrial appendage [LAA] dysfunction (low LAA
velocity, severe spontaneous echo contrast [SEC], LAA thrombus) in patients with
typical atrial fl... |
26,926 | [Detection of Determinants of Functional Aortic Regurgitation in Patients With
Ascending Aorta Aneurism by Transesophagea1 Echocardioscopy]. | We used transesophageal echocardioscopy for the study of effects of linear
parameters of the aortic root and characteristics of its subvalvular space (area
of subvalvular space of the aortic root during diastole and aortic cusps
coaptation height) on severity of aortic regurgitation in patients with aneurism
of asc... |
26,927 | [Comparative Randomized Study of the Effects of Long-Term Therapy With
Rosuvastatin and Combination of Atorvastatin and Ezetimibe on Carbohydrate
Metabolism and Adipokines Levels in Patients With Coronary Artery Disease and
Diabetes Mellitus]. | OBJECTIVE: This open randomized study compares the effects of 24-week-long
treatment with rosuvastatin and with atorvastatin coadministered with ezetimibe
on the parameters of carbohydrate metabolism and the plasma levels of adipokynes
in patients with coronary artery disease and type 2 diabetes mellitus or
impaire... |
26,928 | [The Optimal Allies in the Control Strategy of Hypertension]. | to review the available results of clinical trials on the efficacy and safety of
a fixed combination of an angiotensin-converting enzyme (ACE) inhibitor
lisinopril and the calcium antagonist amlodipine, including an analysis of the
actual antihypertensive effect and organoprotective action in the russian
population... |
26,929 | [Efficiency of Pulmonary Ventilation in Remote Period After Surgery in Patients
With Hronic Pulmonary Thromboembolism]. | AIM: to assess efficiency of pulmonary ventilation in remote period after
surgical treatment of chronic pulmonary thromboembolism (CPTE).
MATERIAL AND METHODS: We examined 29 patients with CPTE with median age 49
(38-60) years. Pulmonary ventilation was studied by body plethysmography and its
efficiency was evaluate... |
26,930 | [Carriage of A Allele of Polymorphic Marker G(-238)A of TNF-alfa Gene Is
Associated With Unfavorable Prognosis in Patients With Chronic Systolic Heart
Failure]. | AIM: to elucidate association between polymorphic markers of interleukin- 6
(Il-6) and tumor necrosis factor (TNF) genes and unfavorable outcomes in
patients with chronic heart failure (CHF).
MATERIAL AND METHODS: We determined levels of TNF and Il-6 and genotypes of
polymorphic markers G(-238)A of TNF gene (rs36152... |
26,931 | [HAS-BLED and HEMORR2HAGES Scales in Assessment of Bleeding Risk in Patients on
Long-Term Warfarin Therapy]. | Aim of the study was to elucidate value of HAS-BLED and HEMORR2HAGES scales for
prediction bleedings in patients receiving long-term warfarin (W) therapy.
MATERIAL AND METHODS: The study involved 119 patients (72 men) aged 60.9+/-9.6
years with atrial fibrillation or venous thromboembolic complications. Follow up
pe... |
26,932 | [Results of Russian Hospital Chronic Heart Failure Registry in Three Subjects of
Russian Federation]. | Aim of the RUssian hoSpital Heart Failure Registry (RUS-HFR) was to analyze
clinical and epidemiological characteristics, application of modern drug and
non-drug therapy among hospitalized patients with systolic chronic heart failure
(CHF) in 3 subjects of Russian Federation.
MATERIAL AND METHODS: We conducted a pro... |
26,933 | [Arterial Hypertension Complicated by Myocardial Hypertrophy and Heart Failure
Is Associated With Lower Serum Levels of Vascular Endothelium Growth Factor
(VEGF-A165)]. | AIM: To study relationships of serum levels of vascular endothelium growth
factor with left ventricular (LV) myocardial hypertrophy (H) and signs of heart
failure (HF) in patients with arterial hypertension (AH).
METHODS: We examined 47 patients with AH and by echo established thickening (
more or equal 16 mm) of LV... |
26,934 | [Combined Antihypertensive Therapy in Patients at High Risk]. | Presents opportunities to increase the effectiveness of combination
antihypertensive therapy (AHT) in patients with arterial hypertension (AH) and
high cardiovascular risk. Displaying increase in the proportion of patients with
target blood pressure up to 82.4%; high commitment combined AHT (96%) and
medical recomm... |
26,935 | [Pharmacoepidemiology of Statins in Patients With Hypertension and
Dyslipidemia]. | Aim of the study was to analyze the validity of pharmacoepidemiological purpose
and structure of lipid-lowering therapy (LLT) in patients with hypertension and
dyslipidemia in clinical practice. Demonstrated commitment to the basic
principles of medical verification of cardiovascular events with an adequate
definit... |
26,936 | [Pharmaco-invasive Approach Aimed at Preserved Left Ventricular Function in
Patients With Stable Coronary Heart Disease Background Carbohydrate Metabolism
Disorders]. | Performed an open, prospective, randomized, controlled clinical trial, including
63 patients stable coronary artery disease on the background of carbohydrate
metabolism disorders. All patients underwent elective coronary stenting.
Patients of the main group (n=32) within 2 weeks before the intervention
received tri... |
26,937 | [Chronic Obstructive Pulmonary Disease as a Factor of Unfavorable Cardiovascular
Prognosis After Percutaneous Coronary Interventions in Ischemic Heart Disease]. | AIM: to elucidate effect of concomitant chronic obstructive pulmonary disease
(COPD) on remote results of percutaneous coronary intervention (PCI) with stent
implantation in patients with ischemic heart disease (IHD).
MATERIAL AND METHOD: We analyzed data of long term follow-up of 346 IHD patients
after PCI with ste... |
26,938 | [Comparison of Novel Oral Anticoagulants and Warfarin in Elderly Patients With
Nonvalvular Atrial Fibrillation]. | We compared efficacy and safety of warfarin with those of direct thrombin
inhibitor dabigatran, factor Xa inhibitors rivaroxaban and apixaban used for
stroke prevention in 280 patients aged 65-80 years with non-valvular atrial
fibrillation. Treatment for two years with dabigatran (110 mg twice daily),
apixaban (5 m... |
26,939 | [Perfusion, Metabolism and Regional Myocardial Contractility in Patients With
Valvular Heart Disease: a Long-Term Follow-Up After Valve Replacement]. | AIM: To perform complex assessment of myocardial perfusion, metabolism, and
regional contractility in patients with valvular heart disease (VHD) in remote
period after surgical correction of heart defects.
MATERIAL AND METHODS: We examined 30 patients with VHD in 1-8 years after heart
valve replacement because of mi... |
26,940 | [Safety and Efficacy of Amlodipine, Lisinopril and Rosuvastatin Therapy in
Patients With Metabolic Syndrome and Nonalcoholic Fatty Liver Disease]. | AIM: To evaluate the efficacy and safety of amlodipin, lisinopril and
rosuvastatin therapy in metabolic syndrome and high cardiovascular risk patients
with nonalcoholic fatty liver disease (NAFLD).
PATIENTS AND METHODS: 6 months randomized study of fixed combination of
amlodipin and lisinopril with or without rosuva... |
26,941 | [Predisposition to Psychological Distress in Patients After Coronary Bypass
Surgery: Relation to One Year Prognosis]. | AIM: to assess effect of type D personality (TDP) on one year prognosis after
coronary artery bypass grafting (CABG).
MATERIAL AND METHODS: Personality type was evaluated using the DS-14 scale in
683 patients before and in 1 year after CABG; 152 patients had TDP, 531 had not.
After 1 year of follow-up we assessed fu... |
26,942 | [Smoking, Telomere Length and Cardiovascular Diseases]. | The role of smoking in the development of various diseases, including
cardiovascular system is widely known and proven. At the same time, given the
multi-component composition of tobacco smoke, many mechanisms of its damaging
effect on the target organs remain unknown. Effect of smoking on duration of
life and risk... |
26,943 | [Psychosocial Aspects in Cardiac Rehabilitation: From Theory to Practice. A
Position Paper From the Cardiac Rehabilitation Section of The European
Association of Cardiovascular Prevention and Rehabilitation of the European
Society of Cardiology]. | A large body of empirical research shows that psychosocial risk factors (PSRFs)
such as low socio-economic status, social isolation, stress, type-D personality,
depression and anxiety increase the risk of incident coronary heart disease
(CHD) and also contribute to poorer health-related quality of life (HRQoL) and
... |
26,944 | [Quality of Life of Patients With Ischemic Heart Disease and Pronounced
Dysfunction of Left Ventricular Myocardium With Medical and Surgical
Treatments]. | We assessed quality of life in 80 patients with ischemic heart disease and
pronounced dysfunction of left ventricular myocardium. Forty patients underwent
coronary bypass surgery and 40 patients received only medical therapy. Duration
of follow-up was 7 years. Baseline quality of life was low in both groups.
Degree... |
26,945 | [Influence of Endothelial Dysfunction on Prognosis of Patients With Non
ST-Segment Elevation Acute Coronary Syndrome]. | We studied relationship between markers of endothelial dysfunction and
multifocal atherosclerosis and adverse coronary events in 82 patients with
non-ST segment elevation acute coronary syndrome (NSTEACS). Eighteen patients
(21.9%) had adverse events during one year of observation. Patients with adverse
coronary ev... |
26,946 | [Stiffness of the Arterial Wall and Central Hemodynamics During Long-Term
Combination Antihypertensive Therapy]. | Aim of the METR study - to assess effect of antihypertensive therapy with fixed
combination of angiotensin converting enzyme inhibitor lisinopril (10 mg) and
calcium antagonist amlodipine (5 mg) on parameters of arterial wall stiffness
and central hemodynamics in patients with stage I-II essential hypertension (EH) ... |
26,947 | [The Use of Dabigatran for Prevention of Thromboembolic Complications in
Patients Underwent Atrial Fibrillation Catheter Ablation]. | The aim of the study was to estimate the efficacy and safety of dabigatran in
comparison with warfarin after atrial fibrillation (AF) catheter ablation (CA).
METHODS: 228 consecutive patients, having undergone AF CA, were enrolled in
retrospective trial. In group I (n=170) warfarin was administered by modified
inter... |
26,948 | [The Use of Rivaroxaban in Perioperative Period of Pulmonary Vein Antrum
Isolation in Patients With Paroxysmal Atrial Fibrillation]. | Results of an observational study. devoted to prevention of thromboembolic
complications in patients with atrial fibrillation undergoing catheter pulmonary
vein atrium isolation are discussed. Patients (n= 199) were divided into two
comparable groups depending on the anticoagulant (rivaroxaban or warfarin) used.
Cl... |
26,949 | [Results of Surgical Treatment of Infective Valvular Endocarditis]. | Immediate and long-term results of surgical treatment of infective valvular
endocarditis (IVE) in 438 patients during the period from 1978 to 2013 are
presented. Overall hospital mortality was 9.1% (11.2 and 6.7% among patients
operated in the active stage of IVE and in remission, respectively) Depending on
the sit... |
26,950 | [Effect of Statins on Development of Early Cognitive Dysfunction After Coronary
Artery Bypass Grafting]. | We studied the effect of rosuvastatin on the development of early postoperative
cognitive dysfunction (POCD) in patients after coronary artery bypass grafting
(CABG). One hundred nine men aged 45-70 year was divided into two groups. Group
1 comprised 69 patients (mean age 56.8 ± 5.2 years) who were given 20 mg of
r... |
26,951 | [The Evolution of Views on Lipoprotein(a): From Biomarker to the Therapeutic
Target]. | Series of experimental, epidemiological, and genetic studies have demonstrated
that elevated lipoprotein(a) [Lp(a)] level is associated with cardiovascular
disease independently from traditional risk factors of atherosclerosis. This
review covers the basics of Lp(a) pathogenicity in atherothrombosis and
scrutinizes... |
26,952 | [Congenital Cardiac Conduction Abnormalities]. | Abnormalities in cardiac conduction can occur due to a variety of factors. So
called "idiopathic", conduction system degeneration develops without evident
causes and may have hereditary basis. In the majority of cases it has no
clinical manifestation, do not require treatment and have overall good
prognosis. In thi... |
26,953 | [Capabilities of Multidetector Computed Tomography in Assessment of
Atherosclerosis of Coronary Arteries]. | The prevalence of ischemic heart disease (IHD) as well as high mortality from
its exacerbations led to an active search and study of diagnostic methods to
predict the possible development of acute coronary events. At the moment, it is
proved that the morphological properties of atherosclerotic plaque largely
determ... |
26,954 | [Comparative Clinical Biochemical Assessment of the State of Myocardium After
Coronary Artery Bypass Surgery Performed Using Various Techniques]. | We compared parameters of the state of myocardium after coronary artery bypass
surgery (CABS) performed according to the following techniques - with complete
cardiopulmonary bypass (CABS-CBP), beating heart bypass grafting with parallel
normothermic perfusion (CABS-BH-NP), and beating heart bypass grafting
(CABS-BH... |
26,955 | [Immediate Results of Mitral Valve Surgery in Asymptomatic Patients With Severe
Mitral Regurgitation Due to Degenerative Mitral Valve Disease]. | Degenerative mitral valve disease nowadays is the most common cause of mitral
insufficiency in developed countries and is associated with high morbidity and
mortality. In the last decades repairing the mitral valve has become the
operation of choice for treatment of the mitral valve prolapse, enabling to
improve th... |
26,956 | [Prognostic Factors of Cardiovascular Complications After Ischemic Stroke]. | We included into prospective cohort observational study 148 patients with
ischemic stroke aged 60 [52; 68] years. Duration of a prospective follow-up was
35 [28; 40] months. Cardiovascular events (CVE) registered during follow-up were
recurrent stroke, transient ischemic attack, myocardial infarction, unstable
angi... |
26,957 | [Inflammatory Markers and Their Role in Assessing Prognosis of Patients With
Stable Coronary Artery Disease After Coronary Stenting]. | In recent years, expanded data have demonstrated the association between
increased inflammatory markers and risk of adverse cardiovascular events in
patients undergoing percutaneous coronary intervention (PCI) with stent
implantation. Particularly, several studies have demonstrated association
between increased C-r... |
26,958 | [First Open Study of Syndrome of Acute Decompensation of Heart Failure and
Concomitant diseases in Russian Federation: Independent Registry ORAKUL]. | Aim of the study was to assess mortality and rate of repetitive hospital
admissions on days 30, 90, 180, 360, of observation as well as prevalence of
concomitant diseases in patients with congestive heart failure (CHF). The
register was formed in 41 centers of 20 cities of Russian Federation. Number of
included pat... |
26,959 | [Prognostic Value of Central Aortic Pressure in Pregnant Women With
Hypertension]. | Prognostic value of central aortic pressure and peripheral blood pressure in
relation to the development of pre-eclampsia was assessed in pregnant women with
different forms of hypertension. It was shown that development of pre-eclampsia
was associated with higher mean 24-hour systolic blood pressure (BP), time inde... |
26,960 | [Blood Lipid Parameters In Populations of Russia, Poland And Czech Republic: The
Hapiee Study]. | PURPOSE: to analyze population values of blood lipid parameters in general
populations of Russia, Poland and Czech Republic.
MATERIALS AND METHODS: In the frame of international project HAPIEE
representative samples of general population were examined in Novosibirsk
(Russia), Krakow (Poland) and six centers in the C... |
26,961 | [Atrial Contractile Function in Patients With Paroxysmal Atrial Fibrillation]. | The aim of study was to investigate atrial contractile function in patients with
paroxysmal atrial fibrillation (AF) in sinus rhythm using transthoracic
echocardiography.
METHODS: 35 patients with paroxysmal AF and arterial hypertension (mean age 62 ±
10 years, 43% males) were enrolled in the study. Control group wa... |
26,962 | [Adherence to Therapy as a Factor Determining Prognosis of Coronary Artery
Bypass Grafting]. | AIM: to study the influence of the patients adherence to the recommended therapy
after coronary artery bypass grafting (CABG) on prognosis of postoperative
period.
MATERIAL: We examined 197 consecutive patients with stable coronary artery
disease (CAD) who had undergone CABG. Age of patients was 38-75 years.
RESULTS... |
26,963 | [The Relationship of Obesity to the Character of Nutrition]. | The aim of the investigation was to study pathogenesis of abdominal obesity on
the model of experimental fatty dystrophy in rats; to assess the state of lipid
and protein metabolism and to elucidate morpho-biochemical interrelations
between pathogenesis of fatty liver dystrophy and character of nutrition.
MATERIAL A... |
26,964 | [Age-related Changes of Left Ventricular Diastolic Function, NT-proBNP Level and
Their Association With Leukocyte Telomere Length]. | With advancing age the left ventricle (LV) undergoes structural and functional
changes, thereby creating the substrate for the development of diseases. One
possible mechanism of the ageing of the heart is cellular senescence. Leukocyte
telomere length (LTL) is a marker of replicative ageing. The purpose of this
stu... |
26,965 | [The Effectiveness of Russian Public Health Recommendations for Sanogennykh
Behavior in the Heatwave]. | There is an urgent need to create adapted for the Russian population of the
recommendations in order to improve the efficiency and automation of the process
of informing patients about the correct (sanogennykh) behavior in the heat. The
proposed health WHO recommendations in 2010 year are difficult to perception,
u... |
26,966 | [Noninvasive Methods of Detection of Vulnerable Atherosclerotic Plaques in
Coronary Arteries]. | In most cases direct cause of acute coronary syndrome and sudden death is an
intracoronary thrombus formed on a surface of unstable atherosclerotic plaque
(UAP). The following are main characteristics of UAP: active inflammation; large
lipid rich nucleus occupying a40% of plaque volume; thin (< 65 mm) fibrous cap;
... |
26,967 | [To the Problem of Selection of Antihypertensive Therapy Scheme From Position of
Cost of Treatment]. | The article is devoted to pharmacoeconomic aspects of treatment of arterial
hypertension including its combination with diabetes mellitus. Data of four
studies of comparison of clinical and economical effectiveness of treatment with
original enalapril and its fixed combination with hydrochlorothiazide with some
gen... |
26,968 | [Brugada Syndrome: Possibilities of the Use of Noninvasive Electrocardiographic
Mapping. A Case Report]. | Patient P., 50 years old, male, with type I Brugada syndrome was examined. The
patient had aborted sudden death event (2006) in his clinical history, ICD Gem
III VR was implanted in 2006, ICDLumax DR was reimplanted in 2012. The patient
had coved type pattern in right precordial ECG-leads. The p.E553X mutation in
S... |
26,969 | [Effect of 12-Months Therapy With Perindopril A on Structural-Functional State
of the Microcirculatory Vascular Bed in Patients With Chronic Heart Failure]. | BACKGROUND: Experimental and clinical data confirm that endothelial dysfunction
(ED) of microvessels is one of mechanisms of progression of chronic heart
failure (CHF).
PURPOSE: To assess the impact of 12-month treatment with perindopril A (5-10
mg/day) on structural and functional state of microcirculatory vascular... |
26,970 | [The Fixed Combination of Amlodipine and Bisoprolol Eliminates the Effect of
-Blockers on Central Pulse Wave in Patients With Arterial Hypertension]. | AIM: to assess effect of -blockers in the characteristics of the central pulse
wave and the effect of switching to a fixed bisoprolol/amlodipine (B/A)
combination.
MATERIAL AND METHODS: Untreated patients (n=28, age 53.6+/-5.7 years, 19 men)
with uncomplicated hypertension without diabetes were given bisoprolol 5-10... |
26,971 | [The Role of Transcriptional Factor Gene TBX5 in Development of Disorders of
Cadiac Conduction]. | In order to study relationship between development of idiopathic
atrioventricular (AV) and intraventricular disorders of cardiac conduction (DCC)
with single nucleotide polymorphism (SNP) of TBX5 gene we examined 260 persons
with primary DCC (71 patients with abnormal AV conduction, 84 and 105 patients
with disorde... |
26,972 | [Early Systolic Dysfunction of Left Ventricular Myocardium Is Reflected On
Electrocardiogram of Patients With Aortic Stenosis]. | AIM: to study relation between electrocardiographic (ECG) criteria of left
ventricular hypertrophy (LVH) and parameters of tissue Doppler (TD) and LV
strain in patients with aortic stenosis (AS) with preserved LV ejection
fraction.
MATERIAL AND METHODS: We examined 80 patients with degenerative AS of all
degrees of... |
26,973 | [Results of Coronary Artery Bypass Surgery Combined With Endarterectomy and
Reconstruction of Anterior Descending Artery in Patients With Diabetes
Mellitus]. | AIM: To assess results of coronary artery bypass surgery combined with
endarterectomy (EAE) in patients with ischemic heart disease (IHD) and diabetes
mellitus (DM), and impact of DM on clinical outcomes.
MATERIAL AND METHODS: We recruited in this study 152 patients with IHD (43 with
and 109 without DM) subjected to... |
26,974 | [Association of Atrial Fibrillation With Mortality From Various Causes in
Population of Russian Federation]. | AIM: to elucidate contribution of atrial fibrillation (AF) to mortality from
various causes among men and women in Russia.
MATERIAL AND METHODS: We analyzed data from samples of population of Moscow and
Petersburg (Leningrad) aged 35-74 years examined in different years. Total
number of subjects was 20045 (15107 men... |
26,975 | [Hormonal and Metabolic Differences in Patients With Coronary Artery Disease]. | To prove the involvement of the autonomic nervous system in the formation of
thrombotic status of the patients. 24 patients with myocardial infarction were
enrolled in the study. Catecholamines levels were compared duing pain episodes
and at rest. Patients were divided in to 2 groups according to the level of
norep... |
26,976 | [Monitoring the Secondary Prevention of Coronary Artery Disease in Europe and
Russia: Results of the Russian Part of the International Multicenter Study
EUROASPIRE IV]. | The results of the Russian part of the EUROASPIRE IV study show that we have a
large room for improvement of traditional risk factors management in CAD
patients hospitalized for acute myocardial infarction, acute coronary syndromes,
PCI or CABG (at average in 1.7 years of follow-up after index events). It is
also t... |
26,977 | [Personal Telemonitoring: Perspectives of Development in Arhythmology and
Cardiology]. | Sudden cardiac death (SCD) persists as one of challenging problems in cardiology
and cardiac surgery, only in Russia costing more than 350,000 deaths annually.
Arrhythmias and ischemic heart disease (IHD) prevail as SCD immediate direct
mechanisms. Unfortunately, timely diagnostics of heart diseases is far below the... |
26,978 | [Pulmonary Hypertension in Takayasu Arteritis]. | Takayasu arteritis is well-known rare form of large vessel vasculitis. Pulmonary
involvement is observed in 50% of cases. However, pulmonary hypertension is a
rare complication of pulmonary artery stenosis. In this article we present a
rare clinical case of Takayasus arteritis with typical stenosis of subclavian,
c... |
26,979 | [Noninvasive Electrophysiological Predictors and Biomarkers of Malignant
Arrhythmias in Patients With Ischemic Heart Disease: a 2-Year Prospective
Follow-up]. | AIM: to assess prognostic value of clinical and instrumental parameters, results
of noninvasive electrophysiological tests and biomarkers as predictors of
malignant ventricular arrhythmias in patients with ischemic heart disease (IHD)
during long-term follow-up as well as during myocardial revascularization
surgery... |
26,980 | [Predictors of Efficacy of Radiofrequency Ablation of Pulmonary Veins Performed
During Coronary Bypass Surgery in Patients With Ischemic Heart Disease and
Paroxysmal Atrial Fibrillation]. | We performed simultaneous coronary artery bypass grafting (CABG) and
radiofrequency ablation (RFA) ostia of pulmonary veins in 254 patients (147 men
and 107 women) with ischemic heart disease and paroxysmal atrial fibrillation
(AF). In-hospital mortality in patients with early recurrence of AF was 8.4%, in
patients... |
26,981 | [The Antihypertensive Effect of the Fixed Combination of Lisinopril and
Amlodipine in Patients With Coronary Heart Disease After Coronary Artery Bypass
Grafting]. | Literature data and results of our own register have indicate that hypertension
is one of the most common risk factor in patients with ischemic heart disease
(IHD) who have undergone coronary artery bypass grafting (CABG). But despite
proven benefits of control of hypertension after CABG adherence of patients to
co... |
26,982 | [An Association Between T455C Polymorphism of Apolipoprotein C-III Gene, Insulin
Resistance and Metabolic Syndrome Components]. | AIM: to study an association between T455C apolipoprotein C-III (apo C-III) gene
polymorphism, insulin resistance (IR), metabolic syndrome (MS) and its
components in a Kyrgyz ethnic group.
MATERIAL AND METHODS: 259 persons: 162 patients with MS and 97 sex and age
matched controls without MS, diabetes mellitus and ca... |
26,983 | [The Action of Apelin-12 and Its Analog on Hemodynamics and Cardiac Contractile
Function of Rats With Isoproterenol-Induced Myocardial Lesion]. | Introduction of isoproterenol (beta-adrenoreceptor agonist) into rats is one of
the widespread experimental models of heart failure. It is caused by diffuse
ischemic damage of cardiomyocytes, followed by development of substitutive
fibrosis. Apelin is a natural regulator of the myocardial contractility. The
effects... |
26,984 | [The Relationship Between Level of End-Products of Tissue Glycation and Pulse
Wave Velocity in Non-diabetic Patients With Cardiovascular Disease]. | AIM: of the study was to assess the relationship between advanced glycation
end-products measured by skin autofluorescence (AGEs) and pulse wave velocity
(PWV) in non-diabetic patients with cardiovascular disease (CVD).
MATERIAL AND METHODS: Skin autofluorescence (AGE--reader, DiagnOptic) and PWV in
humero-malleolar... |
26,985 | [Analysis of Efficiency of the Standard of Sanatorium Care of Patients With
Arterial Hypertension]. | Analysis of efficiency of the standard of sanatorium care of patients with
arterial hypertension is presented. Rates of arbitrary use of methods of care
and their use in accordance with requirements of the standard were compared in
patients with diferent results of treatment. It was found that existing standard
was... |
26,986 | [Opportunities Provided by Stress Echocardiography and Stress Speckle tracking
for the Evaluation of Myocardial Reserve Among Patients With Heart Defects]. | Heart failure risk factors research as well as studies of myocardial dysfunction
to identify subclinical heart disease are important problems that can be solved
with stress echocardiography and new methods of myocardial function analysis.
Key factors defining the prognosis of patients with valvular diseases are hear... |
26,987 | [Effect of Antihypertensive Drugs on Regression of Left Ventricular
Hypertrophy]. | In this review we show that combination treatment with blockers of
renin-angiotensin-aldosterone system and dihydropyridine calcium antagonists
plays the leading role in lowering of left ventricular myocardial mass. We also
demonstrate benefits of the use of fixed combinations of drugs for the treatment
of patients... |
26,988 | [First Experience of Clinical Application of LCZ696--an AT1-angiotensin
Receptors and Neprilysin Inhibitor--in Patients With Chronic Heart Failure and
Reduced Ejection Fraction]. | Simultaneous inhibition of the renin-angiotensin-aldosterone system and the
system of degradation of natriuretic peptides can potentially provide unique
therapeutic effects in patients with chronic heart failure (CHF) with reduced
ejection fraction (EF). Aim of this study was to assess tolerability of therapy
with ... |
26,989 | [Rate of Detection of Atherosclerosis in Patients With ST Elevation Myocardial
Infarction and Concomitant Chronic Obstructive Pulmonary Disease of Light or
Moderate Degree of Severity]. | PURPOSE: to study frequency of detection of atherosclerosis among patients with
ST elevation myocardial infarction (STEMI) and concomitant chronic obstructive
pulmonary disease (COPD) of light or moderate degree of severity, and to
elucidate its relation to lung function and level of C-reactive protein (CRP).
MATERI... |
26,990 | [Pleiotropic Effects of Rosuvastatin in Chronic Obstructive Pulmonary Disease
Patients With High Cardiovascular Risk]. | Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
in the list of common causes of mortality after cardiovascular diseases. The
processes of atherogenesis and cardiovascular diseases are accelerated in
patients with COPD. The key mechanisms of COPD pathogenesis are oxidative
stress, de... |
26,991 | [Risk of Cerebral Complications of Surgical Treatment of Patients With Chronic
Pulmonary Embolism]. | Aim of the study was to assess risk of cerebral complications at the background
of various methods of brain protection during surgery in patients with chronic
pulmonary embolism (PE). We examined 61 patients aged 39-54 years operated
because of chronic PE. Monitoring of cerebral oxygenation (rSO2, %) was
performed ... |
26,992 | [Survival of Overweight Patients After Coronary Artery Bypass Surgery. Does the
"Obesity Paradox" Play a Role?]. | Although excessive body mass and obesity are considered risk factors of a number
of diseases and conditions numerous results of studies evidence for the
existence of the "obesity paradox"--higher long-term survival of overweight and
obese patients. Aim of this study was to elucidate impact of body mass index
(BMI) ... |
26,993 | [Application of CAVI Index in Clinical Practice: Calculated Vascular Age as a
Tool for Decision on Additional Examination of Patients With Cardiovascular
Diseases]. | OBJECTIVE: to analyze correspondence between determination of vascular age of
patients with cardiovascular diseases by volumetric sphygmography and their
chronological age, and to assess the influence of lipid factors and
atherosclerotic lesions in carotid arteries (CA) on parameters associated with
the cardio-ankl... |
26,994 | [Radionuclide Methods in the Assessment of Anthracycline-Induced
Cardiotoxicity]. | PURPOSE: To compare diagnostic efficacy of multigated acquisition (MUGA) scan
and Tc-99m MIBI gated SPECT for evaluation and forecast of anthracycline-induced
cardiotoxicity.
MATERIAL AND METHODS: We included into this study 80 patients (72 women and 8
men, mean age 43 ± 4.2 years) with malignant tumors without over... |
26,995 | [Mechanisms of Vascular Remodeling Following Arterial Injury]. | Arterial remodeling is the process of adaptation of the vessel comprising
multiple structural and functional alterations of the vascular wall that occur
in disease, trauma or aging. Arterial remodeling is accelerated in conditions
that adversely affect the structural and functional balance of the vascular
system, s... |
26,996 | [Sudden Cardiac Death of Young Persons: Risk Factors, Causes, Morphological
Equivalents]. | The article contains literature review on the problem of causes of sudden
cardiac death (SCD) among young people as well as results of author's own
retrospective study of deaths of persons before 39 years based on forensic
autopsies performed during 10 year period. The study of structure and dynamics
of causes of d... |
26,997 | [Assessment of Coronary Plaques in Patients With Acute Coronary Syndrome Without
Persistent ST-Segment Elevation]. | AIM: to analyze morphological features of atherosclerotic plaques in culprit and
non-culprit coronary lesions in patients with non ST-elevation acute coronary
syndrome (NSTE-ACS) by multidetector spiral computed tomography (MDCT). RESULTS.
In culprit lesions (n = 70) compared to non-culprit lesions (n = 144) frequen... |
26,998 | [The State of Hemostasis and Immune System in Patients' With Acute Coronary
Syndrome Combined With Anxiety-Depressive Disorder]. | Anxiety-depressive disorders (ADD) have a negative impact on the course and
prognosis of patients with ischemic heart disease, but the mechanisms of their
correlation are not studied enough. The purpose of this study was to elucidate
special characteristics of hemostasis and immune system in patients with acute
cor... |
26,999 | [Evaluation of Anti-Ischemic and Cardioprotective Effects of Nicorandil in
Patients With Stable Angina]. | The aim of our study was to assess the anti-ischemic and cardiouprotective
efficiency of the activator of potassium channels nicorandil in patients with
stable angina during long-term intake on the background of standard therapy of
coronary heart disease (CHD), including aspirin, rosuvastatin, valsartan and
bisopro... |
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