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26,800 | [Myocardial deformation and rotation in hypertensive men with different degrees
of left ventricular hypertrophy]. | PURPOSE: to assess parameters of myocardial deformation and rotation in
untreated hypertensive men depending on presence and degree of left ventricular
hypertrophy (LVH).
MATERIAL AND METHODS: We examined 98 hypertensive men aged 51 (46-58) years.
Examination included clinical evaluation, conventional transthoracic ... |
26,801 | [Fixed irbesartan/amlodipine combination: efficacy and safety of the use of four
dosing regimens in patients with arterial hypertension]. | AIM: to assess efficacy, safety, and tolerability of 4 fixed
irbesartan/amlodipine combinations in hypertensive patients resistant to
monotherapy with 150 mg irbesartan or 5 mg amlodipine in a 16 week prospective
open uncontrolled randomized multicenter study.
MATERIAL AND METHODS: We included in this study 158 pati... |
26,802 | [Postregistration study of comparative assessment efficacy of the use of fixed
combination of nebivolol and amlodipine for the treatment of patients with
moderate and high degree of arterial hypertension]. | AIM: of the study was to assess efficacy of the use of fixed combination of
nebivolol and amlodipine in patients with moderate and high degree of arterial
hypertension (AH).
MATERIAL AND METHODS: Patients with diagnosis of primary AH (n=124) were divided
into 2 groups by random sample method. Patients of group 1 (n=... |
26,803 | [Lipoprotein-associated phospholipase A2: relation to development of ischemic
stroke in patients with essential hypertension]. | AIM: to investigate association of lipoprotein-associated phospholipase A2
(Lp-PLA2) level (mass) with ischemic stroke in patients with essential
hypertension (EH) with or without dyslipidemia.
MATERIAL AND METHODS: We examined 60 patients with EH without complications and
90patients with EH and history of ischemic ... |
26,804 | [Detection of early markers of atherosclerosis in men with various levels of
risk of cardiovascular complications]. | AIM: to assess rate of additional risk factors, and to elucidate association of
early markers of atherosclerosis with total cardiovascular risk in a cohort of
working age men.
MATERIAL AND METHODS: We examined 200 men aged 40-55 years without overt
cardiovascular (CV) diseases and with various levels of CV risk. Acc... |
26,805 | [Proaterogenic metabolic disorders in patients with chronic kidney disease
nondiabetic origin: possibility of statin therapy]. | PURPOSE AND MATERIAL: In order to study the state of coronary arteries, and
dynamics of parameters of kidney function, lipid metabolism, levels of glycated
hemoglobin (HbA1c), uricemia during administration of atorvastatin in a complex
of standard cardioprotective treatment, we examined 54 patients with chronic
kid... |
26,806 | [Concentration of osteoprotegerin and RANKL in blood serum of patients with
aortic stenosis]. | PURPOSE: to compare blood serum levels of osteoprotegerin (OPG) and soluble
receptor activator of nuclear factor B ligand (sRANKL) in patients with
different morphological variants of stenosis.
MATERIAL AND METHODS: We included in this study 57 patients with aortic
stenosis: 29 with bicuspid aortic valve (BAV) and 2... |
26,807 | [Dynamics of risk of fatal cardiovascular diseases evaluated with the SCORE
scale in men with disorders of fat metabolism]. | In 141 apparently healthy working men aged 55 years (mean) we assessed body mass
index (BMI), states of lipid, carbohydrate and purine metabolism, morphological
and functional state of the cardiovascular system (transthoracic
echocardiography), carotid artery intima-media complex (IMC) (ultrasound
investigation). T... |
26,808 | [Calcification of coronary arteries and dyslipidemia in women with rheumatoid
arthritis]. | OBJECTIVE: to identify features of lipid profile in women with rheumatoid
arthritis (RA) depending on calcification of coronary arteries (CA).
MATERIAL AND METHODS: We examined 40 women with RA (mean age 48.6 ± 1.4 years,
average duration of RA 7.77 ± 1 years) and 22 women of control group. Coronary
artery calcifica... |
26,809 | [Populational characteristics of metabolic syndrome in open male population]. | OBJECTIVE: to assess prevalence of various clusters of metabolic syndrome (MS)
in open male population aged 25- 64 years.
METHODS: This cross sectional epidemiological study was conducted on a
representative population sample formed from lists of male voters in one of
administrative districts in Tumen. NCEP ATP III ... |
26,810 | [Rational approach to administration of combination therapy in arterial
hypertension: modern recommendations and personal experience]. | Modern treatment of arterial hypertension (AH) in based on concept of necessity
of arterial pressure (AP) lowering to target levels for prevention of
cardiovascular (CV) diseases (D) and reduction of cardiovascular mortality. AP
<140/90 and <140/80-85 mm Hg are target levels for general population and
patients with... |
26,811 | [Twelve months results of percutaneous coronary interventions in patients with
ischemic heart disease combined with diabetes mellitus using sirolimus and
everolimus covered stents]. | We included into this study 112 patients with ischemic heart disease (IHD) and
concomitant type 2 diabetes mellitus (DM) subjected to percutaneous coronary
interventions with stenting. Everolimus and sirolimus eluting stents (EES and
SES) were implanted in 54 (group 1) and 58 (group 2) patients, respectively.
After... |
26,812 | [The role of subclinical inflammation in progression of multifocal
atherosclerosis during one year after myocardial infarction]. | AIM: To elucidate role of subclinical inflammation in progression of
atherosclerotic process in magistral noncoronary arteries in patients during one
year after ST-elevation myocardial infarction (MI).
MATERIAL AND METHODS: We examined 168 men with MI (mean age 59.5 years). All
patients during hospitalization underw... |
26,813 | [Clinical aspects of vaso-and cardioprotection in patients with primary and
recurrent myocardial infarction]. | The paper is devoted to characteristics of vascular and cardiac remodeling in
patients with primary and recurrent myocardial infarction (MI). Data on
multifocal atheroslerotic involvement of vessels in these patients associated
with development of multivascular involvement of coronary arteries are
presented. Emphas... |
26,814 | [Analysis of 24-hour blood pressure profile, heart rate variability and carotid
atherosclerosis in hypertensive patients among native and nonnative population
living in Yamalo-Nenets autonomous district]. | OBJECTIVE: To study special characteristics of the course of arterial
hypertension (AH) among native and nonnative population of Yamalo-Nenets
autonomous district.
MATERIAL AND METHODS: We examined 100 residents of Far North with AH (men and
women aged 21-55, mean age 44.08 ± 1.15 years). All patients were divided i... |
26,815 | [Effect of atorvastatin on pro-inflammatory status (in vivo and in vitro) in
patients with essential hypertension and metabolic syndrome]. | AIM: To study effect of atorvastatin on spontaneous production of cytokines and
reactive oxygen species by mononuclear leukocytes of blood of hypertensive
patients with metabolic syndrome in vivo and in vitro.
MATERIAL AND METHODS: We conducted an 8-week open prospective study on 36
patients with essential stage II ... |
26,816 | [Predictors of high-grade ventricular arrhythmias in patients referred for the
coronary angiography]. | Ventricular arrhythmias (VA) are still the leading cause of sudden cardiac death
(SCD). Therefore identification of predictors of high-grade (hg) VA and
stratification of risk of fatal events remain important problems of cardiology.
We analyzed data of 993 patients with and without hgVA according to 24 hours
Holter... |
26,817 | [Cerebral oxygen supply in patients with chronic pulmonary artery embolism]. | Aim of this study was to assess brain oxygen supply in patients with chronic
pulmonary embolism (CPE) for elucidation of factors of risk of neurological
complications in early postoperative period. We examined 34 patients with
diagnosis of CPE. Mean duration of the disease was 3 (1.4-4.2) years. Data on
baseline ce... |
26,818 | [Actual problems of cardiovascular risk in urban population of Ukrain]. | AIM: To study cardiovascular (CV) risk in urban population of Ukraine.
MATERIAL AND METHODS: In a framework of Ukrainian-Russian study conducted in
2009-2013 we registered levels of 20 factors of CV risk in a sample of
population of Dnepropetrovsk (n = 1000, 468 men, 532 women, age 30-69 years) and
assessed prevalen... |
26,819 | [Signs of diabetic cardiomyopathy in patients with controlled arterial
hypertension and early postprandial hyperglycemia]. | AIM: To study signs of diabetic cardiomyopathy (DCM) in nondiabetic patients
with controlled arterial hypertension (AH) and glycemic response during first
hour of glucose tolerance test (GTT).
MATERIAL AND METHODS: Patients (n = 47) with controlled AH were divided into 2
groups according to results of GTT with 75 g ... |
26,820 | [Assessment and reduction of risk of cardiac complications of noncardiac
surgery]. | One of actual problems of modern cardiology is assessment and correction of risk
of cardiac complications of noncardiac surgery. Recommendations on this issue
propose reduction of preoperative examination and wide use of drug therapy,
primarily statins and β-blockers. However, new data accumulated in recent years,
... |
26,821 | [Perioperative therapy with thienopyridines in coronary artery bypass surgery]. | The number of patients taking dual antiplatelet therapy is growing with high
cardiovascular risk associated with even short-time antiplatelets cessation in
some clinical scenarios (e.g., after acute coronary syndrome or percutaneous
coronary interventions). However, sometimes, it is required to hold
antiplatelets p... |
26,822 | [Carnitine as a marker of atherosclerosis and other risks of cardiovascular
diseases]. | L-carnitine was first isolated from the extracts of muscle tissue in 1905 by the
employees of the department of medicinal chemistry at Moscow University. Later
the role of L-carnitine in both the oxidation of long chain fatty acids and the
metabolism of carbohydrates was discovered. Today L-carnitine is not just a d... |
26,823 | [Single Nucleotide Polymorphisms in T-Cadherin Gene (CDH13) Have Cumulative
Effect on Body Mass in Patients With Ischemic Heart Disease]. | BACKGROUND: Low adiponectin concentration observed in obese patients is
associated with a high risk of metabolic disorders and cardiovascular diseases
and could be related to single nucleotide polymorphisms (SNPs) in T-cadherin
gene (CDH13). T-cadherin is a receptor for adiponectin and low-density
lipoprotein. Aim ... |
26,824 | [Cardio-Ankle Vascular Index and Subclinical Peripheral Atherosclerosis in
Patients With Stable Coronary Artery Disease]. | AIM: To study relationship between cardio-ankle vascular index (CAVI) and
subclinical manifestations of noncoronary atherosclerosis in patients with
stable ischemic heart disease (IHD).
MATERIAL AND METHOD: We included into this study 511 patients with IHD examined
within framework of a register of patients before a... |
26,825 | [The Impact of Renal Dysfunction on Outcomes of In-Hospital and Remote Periods
in Patients With ST-Elevation Myocardial Infarction Combined With Type 2
Diabetes Mellitus]. | PURPOSE. To elucidate association of renal dysfunction (RD) with unfavorable
outcomes of in-hospital and long-term (1 year) treatment stages of patients with
ST-elevation (STE) myocardial infarction (M) and concomitant diabetes mellitus
(DM).
MATERIAL AND METHODS: We enrolled in this register study 954 patients (65%... |
26,826 | [Atrial Fibrillation in Patients With Chronic Obstructive Pulmonary Disease Is
Associated With Polymorphism of Interleukin 6 Gene]. | It can be suggested that development of atrial fibrillation (AF) in patients
with chronic obstructive pulmonary disease (COPD) is directly related to the
system of inflammation. Genetic polymorphism of factors of this system can be
one of components of mechanism of AF in COPD. Aim: to elucidate polymorphic
markers ... |
26,827 | [Left Atrial Remodeling and Thromboembolic Risk in Patients With Recurrent
Atrial Fibrillation]. | PURPOSE: To assess the relationship between left ventricular and left atrial
(LA) structural and functional characteristics and thromboembolic (TE) risk in
patients (pts) with recurrent atrial fibrillation (AF).
MATERIAL AND METHODS: Sixty pts (mean age 65 [61; 72] years, 42% men) with
nonvalvular paroxysmal and per... |
26,828 | [The Possibilities of Pharmacological Correction of Endothelial Dysfunction in
Patients With Arterial Hypertension]. | OBJECTIVE: To assess the possibility of a fixed combination of perindopril
arginine and amlodipine in the correction of endothelial dysfunction (ED) in
patients with arterial hypertension (AH).
MATERIAL AND METHODS: The study included 49 patients with hypertension and ED
receiving any antihypertensive therapy and ha... |
26,829 | [Comparative Clinical Biochemical Assesment of the State of Mycardium After
Coronary Artery Bypass Surgery Performed Using Various Techniques]. | We compared parameters of the state of myocardium after coronary artery bypass
surgery (CABS) performed according to the following techniques--with complete
cardiopulmonary bypass (CABS-CBP), beating heart bypass grafting with parallel
normothermic perfusion (CABS- BH-NP), and beating heart bypass grafting
(CABS-BH... |
26,830 | [Immediate Results of Mitral Valve Surgery in Asymptomatic Patients With Severe
Mitral Regurgitation Due to Degenerative Mitral VaIve Disease]. | Degenerative mitral valve disease nowadays is the most common cause of mitral
insufficiency in developed countries and is associated with high morbidity and
mortality. In the last decades repairing the mitral valve has become the
operation of choice for treatment of the mitral valve prolapse, enabling to
improve th... |
26,831 | [Proignostic Factors of Cardiovascular Complications After Ischemic Stroke]. | We included into prospective cohort observational study 148 patients with
ischemic stroke aged 60 [52; 68] years. Duration of a prospective follow-up was
35 [28; 40] months. Cardiovascular events (CVE) registered during follow-up were
recurrent stroke, transient ischemic attack, myocardial infarction, unstable
angi... |
26,832 | [Predictive Value of Renal Dysfunction for Early and Long-Term Outcomes of
Coronary Artery Bypass Grafting]. | AIM: to assess value of renal dysfunction for immediate and long-term prognosis
after coronary artery bypass grafting (CABG).
MATERIAL AND METHODS: We examined 657 patients (419 men and 238 women) aged
54-68 (60.6 ± 5.3) years before and after coronary artery bypass grafting
(CABG). Patients with baseline glomerular... |
26,833 | [Inflammatory Markers and Their RoIe in Assessing Prognosis of patients With
Stable Coronary Artery Disease After Coronary Stenting]. | In recent years, expanded data have demonstrated the association between
increased inflammatory markers and risk of adverse cardiovascular events in
patients undergoing percutaneous coronary intervention (PCI) with stent
implantation. Particularly, several studies have demonstrated association
between increased C-r... |
26,834 | [The Results of Long-Term Observation of Patients Who Participated in the
ADVANCE Trial]. | We present in this article data on the prevalence and risk of complications in
patients with diabetes and hypertension. From the standpoint of current
guidelines on the management of arterial hypertension we consider problems of
target blood pressure levels and choice of antihypertensive drugs in patients
with diab... |
26,835 | [Relationship Between Respiratory Function and Myocardial Structure and Function
in Patients With Type 2 Diabetes Mellitus and Ischemic Heart Disease]. | PURPOSE: to analyze main parameters of respiratory dysfunction in patients with
type 2 diabetes mellitus (DM) with and without concomitant ischemic heart
disease (IHD).
MATERIAL AND METHODS: We examined 104 patients with DM without (n= 64, 61.5%)
and with (n=40, 38.5%) concomitant IHD. Examination included taking me... |
26,836 | [Anxiety and Polymorphism Val66Met of BDNF gene Predictors of Depression
Severity in Ischemic Heart Disease]. | In a framework of search for early predictors of depression in patients with
ischemic heart disease (IHD) we studied effect of molecular- genetic factors
(polymorphism of brain-derived neirotrophic factor - BDNF), personality traits
(anxiety, neuroticism), IHD severity, and psychosocial stressors on
manifestations ... |
26,837 | [Renal Dysfunction in Patients With Ischemic Heart Disease]. | We studied effects of various forms of coronary heart disease on the progression
of renal dysfunction. Three groups of patients were examined: 1 - patients with
exertional angina (n=29), 2 - patients with old myocardial infarction
(postinfarction cardiosclerosis) and exertional angina (n=22), 3 - patients with
atri... |
26,838 | [Cognitive Impairment in Postmenopausal Women With Arterial Hypertension]. | The aim of the study was to assess relationship between organ damage and changes
of cognitive function in postmenopausal women with arterial hypertension during
3 years of follow-up. A total of 55 women (aged 69+/-9,5 years) with stable
course of hypertension were included. During period of observation and treatment... |
26,839 | [Microvolt T-Wave Alternans in Adolescent Elite Athletes]. | Microvolt T-wave alternans (MTA) is one of markers of electrical myocardial
instability.
STUDY AIM: to elucidate normal range of MTA parameters during bicycle exercise
test (ET) in adolescent elite athletes.
MATERIAL AND METHODS: We examined 500 athletes aged 9-18 (mean 16.1+/-2.2) years
members of national teams of... |
26,840 | [The Use of Novel Technologies for Assessment of Myocardial Function in Clinical
Practice]. | Key factors defining the prognosis of patients with heart failure (HF) are
cardiac remodeling and myocardial contractility. New methods of visualization of
myocardial motion gave impulse to research in the area of heart physiology and
pathology. However in clinical practice these methods are still rarely used.
Eval... |
26,841 | [To the Centennial of Norman Holter (19141983)]. | The article is devoted to the centennial of the founder of ambulatory ECG
monitoring Norman Jeffrey Holter (1914-1983). It contains brief history of the
scientists family, and depiction of his own educational way from magister of
chemistry and physics to specialist in nuclear research. His activity during
World War... |
26,842 | [Comparative Assessment of Effects of Isosorbide Dinitrate,
Isosorbide-5-Mononitrate and Nicorandil on the Frequency-of Angina Attacks and
Vasoregulating Endothelial Function in Patients With Ischemic Heart Disease]. | AIM: to compare effects of isosorbide dinitrate, isosorbide-5-mononitrate and
nicorandil on frequency of angina attacks and vasoregulating endothelial
function in patients with ischemic heart disease (IHD).
MATERIAL AND METHODS: In 117 patients with stable II-III functional class angina
we analyzed frequency of angi... |
26,843 | [Type of Thrombolytic Agent and Rate of Acute Kidney Injury in Patients With
Myocardial Infarction]. | Aim of this study was to assess incidence and severity of acute kidney injury
(AKI) in patients with ST-elevation (STE) myocardial infarction (MI) after
thrombolytic therapy with alteplase or streptokinase. Among 292 included
patients (227 men, 65 women, mean age 58+/-11 years) 170 received streptokinase,
122 - alt... |
26,844 | [Plasma Renin Activity and Potential of Indapamide Retard to Improve Control of
Hypertension]. | PURPOSE: to study plasma renin activity (PRA) as a predictor of antihypertensive
response to addition of diuretic to combination of angiotensin-converting enzyme
inhibitor (ACEI) and calcium antagonist (CA).
MATERIAL AND METHODS: The study included 72 patients (39% men, mean age
62.0+/-8.3 years) with uncontrolled d... |
26,845 | [Structural and Functional Remodeling of Vascular Wall in Persons With Family
History of Hypertension]. | Aim of investigation - to study parameters of structural and functional
remodeling of vascular wall in persons with family history of hypertension (with
burdened or positive hypertensive heredity). We examined 95 persons (aged 17 -
28 years) with family history of hypertension (positive hypertensive heredity)
and d... |
26,846 | [Effect of Fixed Lercanidipine/Enalapril Combination on 24-Hour Blood Pressure
Profile in Elderly Patients With Arterial Hypertension]. | We studied effect of therapy with fixed combination of lercanidipine and
enalapril on 24-hour blood pressure (BP) profile in 34 elderly patients (mean
age 76.4+/-5.2 years, 14 men, 20 women) with degree II hypertension. After
clinical examination patients were given lercanidipine/enalapril combination
(10/10 mg/day... |
26,847 | [Biomarkers in Heart Failure: Apelin Level Is not Associated With Presence and
Severity of the Disease]. | We tested possibility of the use of apelin-12 as a biomarker of chronic heart
failure (CHF). The study comprised 108 patients with I-IV functional class CHF
of various etiology (ischemic heart disease, dilation cardiomyopathy) and 40
healthy volunteers. Blood samples were taken at hospital admission before
prescrip... |
26,848 | [Prediction of Subclinical Carotid Atherosclerosis With Parameters of Negative
for Ischemia Exercise Testing]. | AIM: to elucidate relationship between parameters of negative ischemic stress
test and subclinical atherosclerosis of carotid arteries.
MATERIAL AND METHODS: Electrocardiographic stress test on treadmill and
ultrasound study of carotid arteries (CA) were carried out in 204 patients
(100women and 104 men, mean age 54... |
26,849 | [First Results of Analysis of the Russian Part of the European Register on
Cardiac Rehabilitation EuroCaReD (European Cardiac Rehabilitation Database)]. | The joint European Registry of patients with cardiovascular diseases
participating in cardiac rehabilitation programs (European Cardiac
Rehabilitation Database, EuroCaReD) is conducted in collaboration between the
ESC and EACPR). Its main goals were to improve the routine use of cardiac
rehabilitation, to develop j... |
26,850 | [Chronic Mitral Regurgitation in Postmyocardial Infarction Patients: Gender
Differences]. | There are two mechanisms of mitral regurgitation formation in postmyocardial
infarction patients: local myocardial remodeling with changing of mitral chord
tethering, and global myocardial remodeling with dilatation of mitral ring.
Analysis of data of the "Register of provided coronary angiography" showed that
the ... |
26,851 | [Assessment of Risk of Development of Diabetes Mellitus Among Physicians of
Therapeutic Profile: Results of a Screening Study]. | AIM: to assess risk of development of diabetes mellitus (DM) and detection of
other metabolic derangements among physicians-internists.
MATERIAL AND METHODS: In an open clinical screening study participated 117 male
and 167 female physicians mostly cardiologists and internists from various
regions of Russia. All par... |
26,852 | [Efficacy and Safety of Rosuvastatin in Patients of Different Risk Groups of
Developing Cardiovascular]. | The purpose of the review - analysis of randomized clinical trials to evaluate
the efficacy and safety of rosuvastatin in respect of primary and secondary
prevention of cardiovascular events, as well as in patients with acute coronary
syndrome. As a primary pathogenetic therapy aimed at reducing the risk of
cardiov... |
26,853 | [Cardiac Resynchronization Therapy in the Treatment of Heart Failure in
Children]. | Cardiac resynchronizing therapy (CRT) is currently a leading approach to the
treatment of heart failure in adults. However, data regarding application of CRT
in children remain limited and indications for CRT are unclear. There is
evidence that the best treatment outcomes result from the administration of CRT
to th... |
26,854 | [ADVANCE-ON Trial: How to Achieve Maximum Reduction of Mortality in Patients
With Type 2 Diabetes]. | Of 10 261 patients with type 2 diabetes who survived to the end of a randomized
ADVANCE trial 83% were included in the ADVANCE-ON project for observation for 6
years. The difference in the level of blood pressure which had been achieved
during 4.5 years of within trial treatment with fixed perindopril/indapamide
co... |
26,855 | [Prevalence of cardiiovascular risk factors in Russian population of patients
with arterial hypertension]. | We studied prevalence of arterial hypertension (AH) and its association with
major cardiovascular (CV) risk factors among unorganized adult population aged
25-64 years in 10 Russian cities (Volgograd, Voronezh, Ivanovo, Irkutsk,
Krasnoyarsk, Orenburg, Vladikavkaz, Samara, Tomsk, Tyumen) with different
climatic, geo... |
26,856 | [Approaches potentiating cardioprotective effect of ambulatory physical training
in patients with ischemic heart disease and multivessel coronary artery
involvement after coronary stenting]. | Cardiorehabilitation of patients with multivessel coronary lesions is an
obligatory component of ambulatory stage of care. With the aim of potentiating
cardioprotective and antiischemic impact of rehabilitative preventive measures
in 36 patients with ischemic heart disease (IHD) and multivessel coronary artery
invo... |
26,857 | [Polymorphic alele variants of eNOS gene in patients with disorders of cardiac
conduction]. | We studied the role of endothelial nitric oxide synthase gene polymorphism 4a/4b
in development of such disturbances of cardiac conduction as atrioventricular
(AV) block and sick sinus node syndrome (SSNS). We examined 69 subjects (36 men,
33 women) with AV block and 90 subjects (33 men and 57 women) with SSNS. They... |
26,858 | [What physicians think and know about antithrombotic therapy in atrial
fibrillation]. | We conducted an anonymous survey among 382 physicians (58% internists, 42%
cardiologists) in order to obtain information on their opinion on various
aspects of antithrombotic therapy in atrial fibrillation. The survey revealed
low level of awareness about algorithms of stratification of risks of stroke,
systemic em... |
26,859 | [Prognosis of unfavorable cardiac events in patients with severe chronic heart
failure with preserved coronary myocardial reserve]. | OBJECTIVE: To elucidate predictors of unfavorable cardiac events in patients
with non-ischemic cardiomyopathy (CMP) complicated by congestive heart failure
(CHF) with preserved myocardial coronary reserve (MCR).
MATERIAL: We followed 114 patients with non-ischemic MCP and NYHA class III-IV
CHF. MCR was estimated by ... |
26,860 | [Strategy of sinus rhythm restoration after single stage correction of mitral
valve defect and maze procedure for improvement of efficacy and safety of
anticoagulant therapy]. | We analyzed clinical efficacy of a strategy of sinus rhythm (SR) restoration
after single stage correction of mitral valve defect and failed radiofrequency
maze procedure elaborated and realized in the Research Institute for Complex
Issues of Cardiovascular Diseases, and assessed its value for increase of
efficacy ... |
26,861 | [The ability to use meldonium as adaptogen in winter in patients with
cardiovascular disease]. | Given that the effects of frost can play the role of independent stress factor
influencing the course of cardiovascular disease (CVD), it is reasonable to
supplementation of drugs that increase the body's resistance to cold stress.
Aim: To evaluate the possibility of using meldonium to prevent unwanted seasonal
cha... |
26,862 | [Diagnostics of magnesium deficiency and measurements of magnesium
concentrations in biosubstrates in norm and in various pathologies]. | In accordance with the evidence from large-scale studies magnesium deficiency
has a significant negative impact on the cardiovascular system, carbohydrate and
fat metabolism. Diagnosis of magnesium deficiency should be based on clinical
symptoms of magnesium deficit and confirmed by additional diagnostic
methods--E... |
26,863 | [Optimization of organizational approaches to management of patients with
atherosclerosis]. | Despite undoubted achievements of modern cardiology in prevention and treatment
of atherosclerosis, cardiologists, neurologists, and vascular surgeons are still
facing severe stenotic atherosclerotic lesions in different vascular regions,
both symptomatic and asymptomatic. As a rule hemodynamically significant
sten... |
26,864 | [Role of kidney injury molecule-1 (KIM-1) for inhospital event risk assessment
after coronary artery bypass surgery]. | AIM: To assess value of kidney injury molecule-1 (KIM-1) for prediction of
inhospital events in CAD patients undergoing coronary artery bypass graft (CABG)
surgery.
MATERIAL AND METHODS: We analyzed postoperative course of 719 patients subjected
to CABG in Research Institute for Complex Issues of Cardiovascular Dise... |
26,865 | [The features of myocardial deformation of left ventricle in patients with
ischemic heart disease defined by the two dimensional strain method]. | Aim of this study was to assess qualitative and quantitative features of
deformation parameters of left ventricular myocardium in patients with ischemic
heart disease (IHD) with and without history of myocardial infarction (MI) using
two-dimensional strain imaging. We examined 30 patients with clinical IHD with
(gr... |
26,866 | [Evaluating the effectiveness of a fixed combination of amlodipine and
bisoprolol in ambulatory patients with arterial hypertension and ischemic heart
disease]. | To evaluate the efficacy and safety of a fixed-term combination of β-blocker
bisoprolol and the calcium antagonist amlodipine in the outpatient treatment of
patients with arterial hypertension (AH) and coronary heart disease (CHD). The
study involved 100 patients with hypertension 1-3 first degree and CHD, which
pr... |
26,867 | [Efficacy and safety of allapinine and quinidine bisulphate in the treatment of
patients with persistent atrial fibrillation after cardioversion]. | OBJECTIVE: To assess and compare the safety and efficacy of allapinine and
quinidine bisulphate in the treatment of patients with persistent atrial
fibrillation after cardioversion. Design--Prospective, randomised, open study.
Patients--73 consecutive patients (men only, mean age 44 ± 11 years) with
persisnent atri... |
26,868 | [Corrective effect of olmesartan on parameters of the local rigidity using the
echo-tracking technology]. | Purpose of this study was to determine clinical value of intima-media thickness
(IMT) and indicators of local stiffness obtained by ultrasonography of the
carotid arteries by echo-tracking technology in patients with hypertension and
coronary artery disease (CAD), and to assess vasoprotective effect of 24-week
trea... |
26,869 | [One-stage carotid and coronary artery surgeries in the treatment of multifocal
atherosclerosis]. | One of the most severe forms of multifocal atherosclerosis often accompanied by
heart attacks and strokes is concomitant coronary and carotid artery disease.
Unfortunately to date there have been no qualitative randomized trials allowing
us to develop a unified optimal approach to the treatment of this pathology. We... |
26,870 | [Extracellular matrix remodeling myocardium of the left ventricle rats with
experimental heart failure after perindopril and melatonin administration]. | The aim of the study was to examine the reorganization of extracellular matrix
left ventricular myocardium (LVM) rats (n = 38) with experimental heart failure
(EHF) as affected by perindopril and melatonin administration. Rats LVM was
studied using the methods of light microscopy, immunocytochemistry and
morphometr... |
26,871 | [Heart and liver fibrosis: the components of a single equation]. | Myocardial fibrosis plays a key role in the pathogenesis of cardiovascular
diseases. The chronic pressure overload of the heart activates collagen that
leads to its excessive accumulation, fibrosis and cardiac hypertrophy.
Myocardial injury is often accompanied by liver damage. These two processes are
closely linke... |
26,872 | [The use of dabigatran for prevention of ischemic stroke in patiets with atrial
fibrillation: special features of treatment in different clinical situations]. | Atrial fibrillation (AF) is extremely highly prevalent both in Russia and in the
world. Ischemic stroke is a severe complication of AF often resulting in
disability or death. Therefore important role is given to conduct of primary and
secondary prevention of development of thromboembolic complications which is
real... |
26,873 | [The place of pharmacoinvasive management in patients with ST-elevation acute
coronary syndrome in Russia]. | The present article reviews the issues of medical healthcare provision for acute
coronary syndrome (ACS) in the Russian Federation from the perspective of
benefits of pharmacoinvasive management for these patients. A brief analysis of
clinical trials, promoting and defining pharmacoinvasive management as a
preferre... |
26,874 | [Possibilities of Correction of Endothelial Dysfunction at the Background of
Combined Antihypertensive Therapy in Patients With Arterial Hypertension and
Type 2 Diabetes]. | AIM: To evaluate the impact of a 12-week combined antihypertensive therapy with
enalapril + indapamide on endothelial dysfunction in patients with arterial
hypertension (AH) and diabetes mellitus (DM) type 2.
MATERIALS AND METHODS: 30 patients with AH stage II-III and DM type 2 age from
40 to 65 years were included ... |
26,875 | [Correlation of Endothelial Dysfunction With Course of Essential Arterial
hypertension in Adolescence]. | AIM: to study laboratory parameters of endothelial dysfunction (ED) and their
correlation with risk factors (RF) of cardiovascular diseases at early stages of
essential arterial hypertension (AH) in adolescents.
MATERIAL AND METHODS: We examined 299 adolescents aged 12 - 18 years with EAH.
According to results of 24... |
26,876 | [Activity of Vegetative Nervous System and Levels of Inflammatory Cytokines
During Glucose Tolerance Test in Subjects With Optimal and High Normal Blood
Pressure]. | Fourteen patients with high normal (main group) and 15 subjects with optimal
(control group) blood pressure (BP) were examined. Fasting and postprandial (60
and 120 min after oral intake of glucose) levels of glucose, insulin,
interleukin (IL)-1, tumor necrosis factor (TNF)-, and C-reactive protein were
measured. A... |
26,877 | [Clinical and Economic Analysis Riotsiguata in Patients With Unresectable or
Residual Chronic Thromboembolic Pulmonary Hypertension]. | OBJECTIVE: to undertake economic evaluation of riociguat in comparison with
standard practice of treating patients with inoperable or residual chronic
thromboembolic pulmonary hypertension (CTEPH) in Russian healthcare.
METHODS: Standard practice was revealed by means of peer interview. It comprised
bosentan monothe... |
26,878 | [Blood Content of Markers of Inflammation and Cytokines in Patients With
Alcoholic Cardiomyopathy and Ischemic Heart Disease at Various Stages of Heart
Failure]. | We conducted a comparative study of content proinflammatory cytokines,
biomarkers of inflammatory process, biochemical indicators of congestive heart
failure (CHF) and hemodynamic parameters in patients with alcoholic
cardiomyopathy (ACMP) and ischemic heart disease (IHD) with various NYHA
classes. We examined 62 m... |
26,879 | [Clinical and Economic Efficacy of Ivabradine in Patients Suffered Myocardial
Infarction]. | OBJECTIVE: to assess the clinical and cost-effectiveness of the addition to the
treatment of patients with coronary artery disease, myocardial infarction (MI)
If current blocker ivabradine.
MATERIAL AND METHODS: as a basis for pharmacoeconomic research results of the
program are taken battleships, in which 1226 pati... |
26,880 | [Detection of Signs of Thrombus Formation in Patients With Typical Atrial
Flutter]. | AIM: to assess rate of detection of markers of thrombi formation and to
determine whether transthoracic echocardiography data or clinical
characteristics predict severe left atrial appendage [LAA] dysfunction (low LAA
velocity, severe spontaneous echo contrast [SEC], LAA thrombus) in patients with
typical atrial fl... |
26,881 | [Detection of Determinants of Functional Aortic Regurgitation in Patients With
Ascending Aorta Aneurism by Transesophageal Echocardioscopy]. | We used transesophageal echocardioscopy for the study of effects of linear
parameters of the aortic root and characteristics of its subvalvular space (area
of subvalvular space of the aortic root during diastole and aortic cusps
coaptation height) on severity of aortic regurgitation in patients with aneurism
of asc... |
26,882 | [Comparative Randomized Study of the Effects of Long-Term Therapy With
Rosuvastatin and With Combination of Atorvastatin and Ezetimibe on Carbohydrate
Metabolism and Adipokynes Levels in Patients With Coronary Artery Disease and
Diabetes Mellitus]. | OBJECTIVE: This open randomized study compares the effects of 24-week-long
treatment with rosuvastatin and with atorvastatin coadministered with ezetimibe
on the parameters of carbohydrate metabolism and the plasma levels of adipokynes
in patients with coronary artery disease and type 2 diabetes mellitus or
impaire... |
26,883 | [Personalized Risk Assessment of Adverse Cardiovascular Events in Young Patients
With Connective Tissue Dysplasia]. | Adverse cardiovascular manifestations (ACVM) were registered during 7-year
follow-up of young patients with undifferentiated connective tissue dysplasia
(CTD). ACVM developed in 28.42% of patients. Most frequent ACVMs were
extension/aneurysm of the thoracic aorta (10.75%), cerebral vascular syndrome
(10.56%), and a... |
26,884 | [Possible Choice of New Oral Anticoagulants With Non-Valvular Atrial
Fibrillation: a Review of Meta-Analyzes]. | This review presents the results of a meta-analysis including data from all four
studies of new oral anticoagulants for the prevention of stroke or systemic
embolism in patients with non-valvular atrial fibrillation. It was found that
all of the drugs had a favorable risk profile/efficiency, and provides a
signific... |
26,885 | [Optimal Control Strategy Allies in Blood Pressure]. | OBJECTIVE: to review the available results of clinical trials on the efficacy
and safety of a fixed combination of an angiotensin-converting enzyme (ACE)
inhibitor lisinopril and the calcium antagonist amlodipine, including an
analysis of the actual antihypertensive effect and organoprotective action in
the russian... |
26,886 | [Comparison of Empiric and Pharmacogenetic Approaches in Assessment of Efficacy
of Anticoagulant Therapy]. | We compared pharmacogenetic (PG) and standard approaches to selection of
individual dose of warfarin on 2 groups of patients each comprising 17 persons.
In the group with PG selection we took into consideration the result of
preliminary genotyping of polymorphisms of VKORC1 and CYP2C9 genes known to be
associated w... |
26,887 | [Evolution of Lipoprotein(a): From Biomarker to the Therapeutic Target]. | Series of experimental, epidemiological, and genetic studies have demonstrated
that elevated lipoprotein(a) [Lp(a)] level is associated with cardiovascular
disease independently from traditional risk factors of atherosclerosis. This
review covers the basics of Lp(a) pathogenicity in atherothrombosis and
scrutinizes... |
26,888 | [Evaluation of the Antianginal Efficacy of Ivabradine In Patients With Ischemic
Heart Disease Complicated by Heart Failure]. | Results of the multicenter open observational program NACHALO (evaluation of
therapy in patients with combined coronary artery disease and heart failure as
part of daily clinical practice), in which 569 doctors in 58 regions of the
Russian Federation participated, were presented. The program included 2751
patients ... |
26,889 | [Age-related Changes of Left Ventricular Diastolic Function, NT-proBNP Level and
Their Association with Leukocyte Telomere Length]. | With advancing age the left ventricle (LV) undergoes structural and functional
changes, thereby creating the substrate for the development of diseases. One
possible mechanism of the ageing of the heart is cellular senescence. Leukocyte
telomere length (LTL) is a marker of replicative ageing. The purpose of this
stu... |
26,890 | [Brugada Syndrome: Possibilities of the Use of Noninvasive Electrocardiographic
Mapping]. | Patient P., 50 years old, male, with type I Brugada syndrome was examined. The
patient had aborted sudden death event (2006) in his clinical history, ICD Gem
III VR was implanted in 2006, ICDLumax DR was reimplanted in 2012. The patient
had coved type pattern in right precordial ECG-leads. The p.E553X mutation in
S... |
26,891 | [Noninvasive Electrophysiological Predictors and Biomarkers of Malignant
Arrhythmias in Patients With Ischemic Heart Disease: a 2-Year Prospective
Follow-Up]. | AIM: to assess prognostic value of clinical and instrumental parameters, results
of noninvasive electrophysiological tests and biomarkers as predictors of
malignant ventricular arrhythmias in patients with ischemic heart disease (IHD)
during long-term follow-up as well as during myocardial revascularization
surgery... |
26,892 | [Therapy of Arterial Hypertension in Patients With Chronic Heart Failure and
Signs of Chronic Kidney Disease With Fixed Perindopril/Amlodipine Combination]. | PURPOSE: to assess efficacy of a fixed combination of perindopril arginine and
amlodipine besylate in the treatment of hypertensive patients with chronic heart
failure (CHF) and signs of chronic kidney disease (CKD).
MATERIAL AND METHODS: Persons with CKD (n=53, age 64.5+/-8.2years) were selected
from 118 patients w... |
26,893 | [The Antihypertensive Effect of the Fixed Combination of Amlodipine and
Lisinopril in Patients With Coronary Heart Disease After Coronary Artery Bypass
Grafting]. | Literature data and results of our own register have indicate that hypertension
is one of the most common risk factor in patients with ischemic heart disease
(IHD) who have undergone coronary artery bypass grafting (CABG). But despite
proven benefits of control of hypertension after CABG adherence of patients to
co... |
26,894 | [What Are the Realities of Prescription and Control of Antithrombotic Therapy in
Atrial Fibrillation in Outpatient Practice?]. | We analyzed documentation of 648 outpatients with nonvalvular atrial
fibrillation receiving ambulatory care in 3 cities in Russia (Moscow, Krasnodar,
and Bryansk). Frequency of use of any anticoagulant in patients with AF and high
risk of stroke and systemic embolism was low (30.9% overall, novel oral
anticoagulant... |
26,895 | [Changes in Cerebral Blood Flow and Cognitive Function in Patients Undergoing
Coronary Bypass Surgery With Cardiopulmonary Bypass]. | PURPOSE: to study effect of coronary artery bypass graft (CABG) surgery with
cardiopulmonary bypass (CPB) on regional cerebral blood flow and cognitive
function in patients with ischemic heart disease (IHD).
MATERIAL AND METHODS: We included into this study 22 patients with IHD subjected
to CABG surgery with CPB. Al... |
26,896 | [Association Between T455C Polymorphism of Apolipoprotein C-III Gene, Insulin
Resistance and Metabolic Syndrome Components]. | AIM: to study an association between T455C apolipoprotein C-III (apo C-III) gene
polymorphism, insulin resistance (IR), metabolic syndrome (MS) and its
components in a Kyrgyz ethnic group.
MATERIAL AND METHODS: 259 persons: 162 patients with MS and 97 sex and age
matched controls without MS, diabetes mellitus and ca... |
26,897 | [Relationship between respiratory function and myocardial structure and function
in patients with type 2 diabetes mellitus and ischemic heart disease]. | PURPOSE: To analyze main parameters of respiratory dysfunction in patients with
type 2 diabetes mellitus (DM) with and without concomitant ischemic heart
disease (IHD).
MATERIAL AND METHODS: We examined 104 patients with DM without (n = 64, 61.5%)
and with (n = 40, 38.5%) concomitant IHD. Examination included taking... |
26,898 | [Anxiety and polymorphism Val66Met of BDNF gene--predictors of depression
severity in ischemic heart disease]. | In a framework of search for early predictors of depression in patients with
ischemic heart disease (IHD) we studied effect of molecular-genetic factors
(polymorphism of brain-derived neirotrophic factor--BDNF), personality traits
(anxiety, neuroticism), IHD severity, and psychosocial stressors on
manifestations of... |
26,899 | [Content of circulating endothelial progenitor cells in patients with chronic
ischemic heart failure with preserved left ventricular ejection fraction]. | PURPOSE: To assess content of various subpopulations of endothelial progenitor
cells (EPC) with CD45-CD34+, CD14+CD309+ and CD14+CD309+Tie2+ phenotypes in
patients with chronic heart failure (CHF) of ischemic origin with preserved left
ventricular ejection fraction.
MATERIAL AND METHODS: We included into the study 1... |
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