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27,100 | [Content of microelements in left ventricular myocardium of patients with
ischemic heart disease. Data of roentgenofluorescent analysis with the use of
synchrotron irradiation]. | Contents of 11 microelements (Se, Rb, K, Sr, Ca, Cr, Mn, Fe, Cu, Ni, Zn) in
various parts (zone of infarction, of scar, periinfaction zone) of left
ventricular myocardium of patients with ischemic heart disease was studied with
method of rentgenofluorescent analysis with the use of synchrotron irradiation
(overall ... |
27,101 | [Effect of eprosartan on psychophysiological functions of drivers with arterial
hypertension]. | Antihypertensive drug eprosartan from the group of angiotensin II receptor
blockers was studied from the position of its effect on professionally
significant psychophysiological qualities of train drivers, which were assessed
with the help of psychophysiological tests. One hundred drivers with arterial
hypertension... |
27,102 | [Peculiarities of interval QT changes and its prognostic role in patients with
acute myocardial infarction]. | Prognostic significance of duration and dispersion of interval QT as well as
relationship of these parameters to other clinical and instrumental signs were
studied in 220 survivors of acute myocardial infarction (MI). These patients
were examined on days 10-14 of MI and then followed for 12-36 months. Values of
cor... |
27,103 | [Special features of pathogenesis and pharmacotherapy of chronic heart failure
in women]. | At present in Europe number of deaths due to diseases of cardiovascular system
in women has exceeded number of deaths in men. It has been established that
process of cardiac remodeling proceeds differently in women and men. This
determines different prognosis of the course of chronic heart failure. So after
acute m... |
27,104 | [On the possibility of amiodarone use in some cases of persistent atrial
fibrillation]. | Aim of the study was to investigate mechanisms of amiodarone action on atrial
and ventricular rhythm during persistent atrial fibrillation (PAF), and to
assess efficacy of amiodarone as monotherapy or in combination with digoxin.
Holter ECG monitoring and registration of high resolution ECG with construction
of per... |
27,105 | [Torasemide--new generation loop diuretic: clinical pharmacology and therapeutic
application]. | Peculiarities of clinical pharmacology of new generation loop diuretic
torasemide and its possible place in the treatment of arterial hypertension,
chronic heart failure (CHF) and liver cirrhosis are considered. Main advantage
of torasemide over loop diuretics of furosemide and bumetamide type is that in
addiction ... |
27,106 | [Nitrates in the practice of treatment of cardiovascular diseases]. | Mechanisms of emergence of endothelial dysfunction underlying development of
ischemic heart disease with peculiarities of its 24-hour cycles are considered
in detail. Data on metabolism of organic nitrates, determining basis of
"replacement" therapy with nitrates in deficit of nitric oxide (endothelium
dependent fa... |
27,107 | [Neoangiogenesis and coronary atherosclerosis: diagnostic value of a novel
biochemical marker placenta growth factor in patients with ischemic heart
disease]. | BACKGROUND: Placenta growth factor (PlGF), a member of the vascular endothelial
growth factor family, promotes neoarteriogenesis and triggers intraplaque
inflammation thereby stimulating atherosclerotic plaque progression and plaque
rupture.
OBJECTIVE: To investigate prognostic significance of circulating placenta g... |
27,108 | [Echocardiography of operated heart. Assessment of results of mitral
valvuloplasty]. | AIM: To assess results of surgery and to elaborate criteria of noninvasive
diagnosis of cardiac function in patients with rheumatic mitral disease after
reconstructive interventions on mitral valve.
MATERIAL: Patients (n=192, mean age 41.2+/-1.2 years) with pure mitral stenosis
(76%) and combined mitral valve diseas... |
27,109 | [Efficacy of the use of sirolimus covered stents in the treatment of diffuse
atherosclerotic lesions of coronary arteries]. | Aim of the study was to compare efficacy of sirolimus covered (116 patients,
group 1) and bare (117 patients, group 2) stents. Groups were comparable
according to main characteristics. Proportion of patients with diabetes was 19
and 13.7%, with multivessel lesions--87.1 and 80.4%, with arterial diameter
<2.75 mm--4... |
27,110 | [QT rate dependence in norm and myocardial infarction]. | AIM: To assess QT/RR relationship in healthy subjects and in patients with acute
myocardial infarction (AMI) using long term 12-lead ECG monitoring.
MATERIAL AND METHODS: We studied separately diurnal and nocturnal QT interval
rate-dependence using a linear model "QT=beta+alphaxRR" in 42 patients with AMI
on 2-nd we... |
27,111 | [Syndrome of white coat hypertension in pregnant women]. | Among 127 pregnant women with hypertension 17 (13.4%) were found to have white
coat hypertension because they had elevated blood pressure (BP) according to
office measurements and normal BP during 24-hour BP monitoring. Investigation of
b-adrenoreception of erythrocyte membranes and analysis of calculated parameters... |
27,112 | [Possibilities of myocardial cytoprotection in complex treatment of patients
with chronic heart failure]. | Efficacy of metabolic therapy with trimetazidine MR and
3-(2,2,2-trimethylhydrazyn) propionatodihydratum (3-TMHP) was compared in
patients with chronic heart failure (CHF) of ischemic genesis.
Clinico-functional examination included dobutamine stress echocardiography
single photon emission computer tomography (SPEC... |
27,113 | [Preventive efficacy of propafenone, its effect on functional state of the heart
during long-term treatment of patients with paroxysmal atrioventricular
arrhythmias]. | Efficacy and tolerability of propafenone were studied in the process of
long-term treatment of patients with various forms of paroxysmal
atrioventricular arrhythmias. It was established that propafenone appears to be
highly effective remedy for prophylaxis of paroxysms of atrioventricular
reciprocal nodal tachycard... |
27,114 | [Changes of parameters of hemodynamics and systems of neurohumoral regulation in
patients with implanted cardiac pacemakers after switching from DDD to VVI
pacing mode]. | To study complex of pathogenetic changes arising during VVI mode single chamber
ventricular pacing we temporarily (for 1 hour) switched pacing mode from dual
(DDD) to single (VVI) chamber stimulation in 11 patients. Parameters studied
were cardiac output (CO), total peripheral vascular resistance (TPVR), levels of
... |
27,115 | [Angiotensin converting enzyme inhibitor moexipril in the treatment of arterial
hypertension. Possibilities of moexipril in the treatment of postmenopausal
women]. | Data on efficacy and safety of angiotensin converting enzyme inhibitor moexipril
in the treatment of arterial hypertension are reviewed. Such advantages of this
preparation as 24-hour duration of action, lack of loss of hypotensive effect
during long term administration, metabolic neutrality, and low rate of side
e... |
27,116 | [Computed tomography of coronary arteries]. | The review covers possibilities of modern techniques of computer tomography (CT)
of coronary arteries: electron beam tomography and 4-, 16-, 64-slice
multi-spiral CT. Main studies conducted in this area are analyzed. Results of
these studies (values of sensitivity and specificity, numbers of included
patients, numb... |
27,117 | [Heart rate variability in chronic heart failure and its role in prognosis of
the disease.]. | Aim. To assess role of 24 hour heart rate variability (HRV) for prognosis of
patients with chronic heart failure (CHF) and systolic dysfunction in the era of
wide use of b-adrenoblockers. Material. Patients (n=135) with symptomatic CHF
and ischemic (68%) or nonischemic cardiomyopathy (32%) with systolic left
ventri... |
27,118 | [Short Term Simvastatin Use in Patients With Systolic Heart Failure of Ischemic
Origin Did Not Preclude Elevation of N-Terminal pro-Brain Natriuretic Peptide
Level.]. | Effect of statins on N-terminal pro-brain natriuretic peptide (NT-proBNP) in
patients with heart failure has not been well elucidated. Purpose. To assess
changes of NT-proBNP during short term use of simvastatin in patients with
coronary heart disease (CHD) and chronic systolic heart failure. Patients and
methods. ... |
27,119 | [Efficacy and Safety of a Domestic Non-selective b-adrenoblocker Possibilities
of the Use of Proxodolol in the Treatment of Patients With Chronic Heart
Failure.]. | Novel (made in Russia) nonselective b-blocker with a1-blocking properties
proxodolol was given to 30 patients with ischemic heart disease, NYHA class
II-III chronic heart failure (CHF) and left ventricular ejection fraction (LVEF)
<40%. Methods of control included clinical examination, registration of
hemodynamic a... |
27,120 | [Effect of Type 2 Diabetes on Results of Endovascular Treatment of Ischemic
Heart Disease With Drug Covered Stents (Results of 1 Year Follow-up).]. | Aim of the study was to determine the impact of sirolimus-eluting stents (SES)
on clinical outcomes in patients with type 2 diabetes mellitus (DM) undergoing
coronary revascularisation. The study enrolled 99 diabetic patients with de novo
lesions in native coronary arteries. Medically treated DM was present in 61
p... |
27,121 | [Dynamics of Fatty Acid binding protein and pro-brain natriuretic Peptide levels
in patients with ischemic heart disease at the background of stress test and
balloon coronary angioplasty.]. | Dynamics of fatty acid binding protein (FABP) and pro-brain natriuretic peptide
(pro-BNP) levels was studied in patients with ischemic heart disease at rest,
during transitory myocardial ischemia, and before and after balloon angioplasty.
Forty patients were included: 25 patients with stable angina comprised the stu... |
27,122 | [Expediency of the use of fibrates for primary and secondary prevention of
cardiovascular complications.]. | Fibrates primarily cause lowering of triglycerides and elevation of high density
cholesterol levels. In WHO, HHS and VA-HIT trials fibrates were shown to
decrease development of complications of cardiovascular diseases. Efficacy of
fenofibrate in subjects with moderate risk and type 2 diabetes combined with
mild dy... |
27,123 | [Echocardiographic assessment of results of single stage mitral and aortic
valvuloplasty]. | Echocardiographic assessment of results of single stage mitral and aortic
valvuloplasty was carried out in 29 patients (mean age 44.1+/-1.2 years) with
combined rheumatic mitral and aortic valve disease. Dynamics of most of
ultrasound parameters of the heart after double intervention on mitral and
aortic valves was... |
27,124 | [Visceral obesity as a pathogenetic factor of ischemic heart disease]. | Relationship between visceral obesity and development of ischemic heart disease
(IHD) has been widely studied during last years. Fat tissue is considered to be
endocrine and secretory organ liberating wide spectrum of protein and signal
factors-adipokines. We studied 27 healthy subjects and 55 patients (including 39... |
27,125 | [Peculiarities of regulatory mechanisms of autonomic nervous system in patients
with arterial hypertension and disturbed 24-hour blood pressure profile]. | BACKGROUND: Insufficient nocturnal blood pressure (BP) decline is associated
with elevated risk of complications of hypertensive disease. Heart rate
variability (HRV) reflects activity of sympathetic and parasympathetic parts of
autonomic nervous system.
AIM: To elucidate special characteristics of HRV in patients w... |
27,126 | [Prevention of ischemic stroke in middle aged patients with atrial fibrillation.
Effect of sinus rhythm maintenance, aspirin, warfarin, and simvastatin]. | Patients (n=263, age 49-64 years) with persistent nonvalvular atrial
fibrillation were subjected to controlled treatment aimed at restoration and
maintenance of sinus rhythm (n=134) or slowing of rate of ventricular
contractions. Efficacy of complementary use of combination of simvastatin with
aspirin, warfarin and... |
27,127 | [Effect of corticosterone and plasma lipoproteins on working capacity and
ultrastructure of isolated rat heart]. | Blood lipoproteins (very low density--VLDL, low density--LDL and high
density--HDL) penetrate into the myocardium through capillary endothelial layer
via receptor mediated endocytosis (all lipoproteins), nonreceptor uptake, or
along interendothelial gaps (LDL). In the myocardium lipoproteins are captured
by interst... |
27,128 | [Bone marrow stem cells in the treatment of ischemic heart disease]. | Cardiac cells possess limited ability to regeneration. Therefore acute
myocardial infarction results in replacement of "perished" cardiomyocytes by
scar tissue. The consequence of this is lowering of myocardial contractile
function and development of heart failure. Novel approach to improvement of
blood supply, con... |
27,129 | [Inflammation and chronic heart failure. The role of statins]. | Immune inflammation is an important link in pathogenesis of chronic heart
failure (CHF). It has been proven that hyperproduction of proinflammatory
cytokines (TNFa, IL-6, IL-1, etc) with associated endothelial dysfunction and
oxidative stress affect unfavorably clinico-hemodynamic parameters and prognosis
of life o... |
27,130 | [Effect of therapy with atorvastatin on parameters of postprandial lipemia and
factors of inflammation in patients with ischemic heart disease]. | Reaction of parameters of lipid transport system to standard fat load (J.Patsch
method), C-reactive protein (CRP) and fibrinogen levels were studied in 30
patients with ischemic heart disease before and after 3 months of therapy with
atorvastatin (10 mg/day). Atorvastatin therapy resulted in 25, 34, 17 and 16%
lowe... |
27,131 | [Insulin-glucose parameters in healthy women and patients with arterial
hypertension and ischemic heart disease in dependence on age and
follicle-stimulating hormone levels]. | Insulin-glucose parameters in healthy women do not significantly change with
changes of functional state of ovaries. Women with hypertension and normal
levels of glycemia have significantly higher values of basal insulinemia and
HOMA-R index reflecting presence of moderate insulin resistance degree of which
is more... |
27,132 | [Immediate results of endovascular treatment of coronary arteries in patients
with ischemic heart disease]. | AIM: To assess immediate results of percutaneous coronary interventions (PCI)
and finding the predictors of the successful outcomes in various subgroups of
patients with coronary artery disease (CAD).
MATERIAL: Patients (n=1066, (average age 55.7+/-9.2 years, women 12%) treated
with coronary artery stenting between ... |
27,133 | [Derangements of contractility of left ventricular myocardium in patients
subjected to coronary bypass surgery. Methods of their correction]. | Coronary bypass grafting with the use of cardiopulmonary bypass was performed in
119 patients (age 41-75 years) with stable angina. In addition to standard
therapy in pre and post operative periods patients of group 1 (n=40) received
mildronate (750 mg/day for 3 days then 750 mg twice weekly), patients of group 2
(... |
27,134 | [Randomized FARVATER study. Part 2. Effect of atorvastatin on endothelial
function, distensibility and stiffness of vascular wall]. | AIM: To elucidate effect of two doses of atorvastatin (10 and 20 mg/day) on
endothelial function, distensibility and stiffness of vascular wall.
MATERIAL AND METHODS: Patients (n=50) with documented ischemic heart disease and
hyperlipidemia were randomized to 10 or 20 mg/day of atorvastatin (Atoris,
KRKA). Endotheli... |
27,135 | [Effect of cardiac resynchronization therapy on quality of life of patients with
chronic heart failure]. | AIM: To study quality of life of heart failure patients who underwent cardiac
resynchronization therapy.
MATERIAL AND METHODS: Cardiac resynchronization devices were implanted to 27
consecutive patients (69.7+/-11.9 years of age) with severe heart failure (NYHA
class III-IV). Follow up period was 11.6+/-4.9 months. ... |
27,136 | [Pulmonary hypertension and right ventricular failure. Part VII. Epidemiology,
risk factors, and pathogenesis of primary (idiopathic) pulmonary arterial
hypertension]. | In a series of articles the authors discuss literature data concerning
epidemiology of pulmonary arterial hypertension (PAH), its modern
classification; peculiarities of its pathogenesis and analysis of results of
epidemiological and cohort studies. Rate of new cases of PAH is 1-2, prevalence
- approximately 15 cas... |
27,137 | [ Psychological stress and acknowledgement of its value as a first order
cardiovascular risk factor]. | The paper contains analysis of results of recent studies of relationships
between stress and cardiovascular morbidity and mortality. A variety of stress
reactions are depicted: acute stress, chronic stress, as well as models of work
stress. Pathophysiologic mechanisms of links between stress and cardiovascular
morb... |
27,138 | [Sensitization of lymphocytes to insulin as one of risk factors of ischemic
heart disease]. | Prevalence and character of sensitization of lymphocytes to insulin and its
prognostic significance were studied in 71 patients with ischemic heart disease
and 55 healthy people. Direct overt sensitization of lymphocytes to insulin was
found in 14 of 71 patients (p<0.01 compared with control group). This type of
re... |
27,139 | [Ischemic heart disease in patients with schizophrenia (clinico-epidemiological
study)]. | We carried out a multicenter controlled study of case histories of patients with
schizophrenia and acute myocardial infarction (AMI) or postinfarction
cardiosclerosis (PIC) from cardiological (n=44), psychosomatic (n=19) and
psychiatric (n=23) hospitals was. In hospital mortality, ischemic heart disease
(IHD) risk ... |
27,140 | [Clinico-epidemiological program of the study of depression in cardiological
practice in patients with arterial hypertension and ischemic heart disease
(COORDINATA)]. | COORDINATA - first Russian multicenter prospective (3 year long) study having
the aim to elucidate prevalence of symptoms of anxiety and depression among
patients with arterial hypertension (AH) and ischemic heart disease (IHD) and
their influence on cardiovascular (CV) prognosis. Results of baseline
epidemiologica... |
27,141 | [Problems of a physician-patient interaction and control of arterial
hypertension in Russia. Main results of scientific-practical program ARGUS-2]. | OBJECTIVE: To study the problems of physician-patient cooperation, patient- and
physician related barrieres to target blood pressure (BP) achievement and to
demonstrate improvement of BP control with indapamide SR 1.5 mg, when given to
patients remaining uncontrolled while receiving antihypertensive therapy without ... |
27,142 | [The efficacy and safety of nibentan for pharmacological cardioversion in
patients with persistent atrial fibrillation and flutter: the role of dose
limitation and magnesium sulfate administration]. | The aim of the study was to evaluate the influence of magnesium sulfate on the
efficacy and safety of pharmacological cardioversion with nibentan (NB) in doses
up to 0,125 mg/kg in patients with persistent atrial fibrillation (AF) and
flutter (AFL). Calculated dose of NB was 0.125 mg/kg. It was administered as 2
bo... |
27,143 | [Chronic asymptomatic hyperuricemia as a marker of atherogenic risk in
children]. | A cross-sectional study of a representative sample of boys aged 7-17 years
(n=569) was carried out in Arkhangelsk. The rate of asymptomatic hyperuricemia
was 27.59 %. Serum level of uric acid correlated with levels of triglycerides,
total cholesterol, low density lipoprotein cholesterol, fasting glycemia,
systolic ... |
27,144 | [Pulmonary hypertension and right ventricular failure. Part VIII. Diagnosis,
course, and prognosis of primary (idiopathic) pulmonary arterial hypertension]. | In a series of articles the authors discuss literature data concerning
epidemiology of pulmonary hypertension (PH), its modern classification;
peculiarities of its pathogenesis and treatment in various diseases and
conditions. In the eight communication they describe presentations of PH and
methods of its instrumen... |
27,145 | [Experimental and theoretical analysis of the role of cholinergically induced
local non-excitability in atrial fibrillation and flutter]. | Excitation of vagal nerves results in the emergence of temporarily inexcitable
regions in atria. The fact is shown using microelectrode techniques and the
mapping of excitation on frog atria isolated together with vago-sympathetic
trunks. These regions serve as unidirectional block and functional obstacle
provoking... |
27,146 | [Role of tissue Doppler echocardiography in the diagnosis of right ventricular
dysfunction in patients with chronic functional class I-IV heart failure]. | A left or/and right ventricular (LV, RV) defection can cause chronic heart
failure (CHF). It is well known that patients with pronounced RV CHF have worse
prognosis and need serious intervention including heart transplantation. But RV
non-invasive methods for diastolic dysfunctions are limited. Some of them, for
in... |
27,147 | [Oxygen-transport function of the blood and endothelial dysfunction in patients
with angina pectoris and arterial hypertension]. | Parameters of oxygen-transport function of the blood and function of the
endothelium were studied in 49 patients with stable angina pectoris of I and II
functional class with or without concomitant 2nd degree arterial hypertension.
All patients received pathogenetic therapy. Signs of endothelial dysfunction
were fo... |
27,148 | [Comprehensive assessment of ischemic episodes and vasomotor function of
vascular endothelium in patients with type II diabetes mellitus]. | Value of functional state of endothelium in assessment of episodes of ischemia
was studied in 93 patients (52 men and 41 women, mean age 58.3 +/- 4.8 years)
divided into 2 groups. Group 1 comprised 47 patients with ischemic heart disease
(IHD) and type II diabetes, group 2 comprised 46 patients with IHD without
dis... |
27,149 | [Functional state of endothelium and oxidant activity of leucocytes in patients
with ischemic heart disease after coronary bypass surgery]. | Relationship between disorders of endothelial function, proinflammatory activity
of leucocytes and effects of therapy with simvastatin or its combination with
ezetimibe was studied in 72 patients with ischemic heart disease subjected to
coronary artery bypass grafting (CABG). Vascular endothelial function was
asses... |
27,150 | [Effect of atorvastatin therapy on the level of secretory phospholipase A2 group
IIA and on the modification of low density lipoproteins in patients with
ischemic heart disease]. | We studied effect of atorvastatin on secretory phospholipase A2 group IIA
(sPLA2-IIA) in blood serum of patients with ischemic heart disease (IHD), lipid
composition of low density lipoproteins (LDL) and process of modification of LDL
induced by sPLA2-IIA in 20 patients taking 20 mg/day of atorvastatin for 3
months... |
27,151 | [Indapamide retard and enalapril in patients with arterial hypertension:
hypotensive effectiveness and effect on endothelial function]. | AIM: To find out what type of therapy was better for restoration of 24 hour
blood pressure (BP) rhythm and impaired function of vascular endothelium, and to
determine preferential therapy for patients with severe endothelial dysfunction.
METHODS: We performed ambulatory blood pressure monitoring and assessments of
e... |
27,152 | [Specifics of distribution of polymorphic markers of the
renin-angiotensin-system genes, relation to ventricular hypertrophy in patients
with essential hypertension of Uzbek nationality]. | AIM: To study distribution of polymorphisms of angiotensin converting enzyme
(ACE), angiotensin II type 1 receptor (AT1R), aldosterone synthase (CYP11B2)
genes, and their association with processes of left ventricular remodeling in
men of uzbek nationality with essential hypertension (EH).
MATERIAL AND METHODS: Pati... |
27,153 | [Effect of treatment with amiodarone on sinus node function]. | Treatment with amiodarone is often associated with sinus bradycardia. We studied
477 patients (mean age 48.7 +/- 0.7 years) with various cardiac rhythm
disturbances. Most patients had ischemic heart disease. Average saturation dose
of amiodarone was 809.4 +/- 13.4 mg/day, average maintenance dose - 263.2 +/-
5.4 mg... |
27,154 | [Ultrasound assessment of hemodynamic parameters in patients with coarctation of
the aorta in the immediate and remote postoperative period]. | We examined 97 patients aged 14 days - 21 years with coarctation of the aorta
(CA) and studied effect of high pressure and pressure gradient in the region of
CA (DeltaP(CA)) on cardiac pump function and reserve capacity of the left
ventricle. Children with left ventricular (LV) ejection fraction (EF) below 30%
(n=2... |
27,155 | [Pulmonary hypertension and right ventricular failure. Part IX. Traditional
therapy of primary pulmonary arterial hypertension]. | In a series of articles the authors discuss literature data concerning
epidemiology of pulmonary hypertension (PH), its modern classification;
peculiarities of its pathogenesis and treatment in various diseases and
conditions. In the nine communication they describe presentations of PH and
methods of its instrument... |
27,156 | [Revascularization of the myocardium in patients with ischemic heart disease.
Experience of the use of sirolimus eluting stents]. | The author presented a review of clinical research works conducted and completed
in 2001 - 2005. The review contains data on clinical trials of sirolimus-eluting
stents in patients with coronary artery disease. The author analyzed
experimental data on the mechanism of action of rapamycin on the cell and also
analyz... |
27,157 | [Possibilities of early surgical correction of postinfarction remodeling of the
heart]. | Postinfarction remodeling of the heart (PIRH) has unfavorable prognostic value
because is associated with elevated risk of fatal arrhythmias, emergence and
progression of heart failure. Reversibility of PIRH in early period after
myocardial infarction causes interest. We followed dynamics of
echocardiographical par... |
27,158 | [The role of brain natriuretic peptide in diagnosis of diastolic myocardial
dysfunction in patients with predialysis chronic kidney disease]. | Aim of the study was to elucidate possibility of the use of brain and atrial
natriuretic peptide (BNP) as a diagnostic marker of diastolic dysfunction (DD)
of the left ventricular myocardium in 37 patients with predialysis chronic
kidney disease (CKD). We used data of echocardiography and Doppler
echocardiography f... |
27,159 | [Clinico-diagnostic significance of cytokine activation and changes of
morphofunctional parameters of the heart in patients with chronic heart failure
and possibilities of correction of revealed disturbances with simvastatin]. | AIM: To study clinico-diagnostic significance of cytokine activation, changes of
levels of inflammatory cytokines in blood serum and main morphofunctional
parameters of the heart in patients with chronic heart failure (CHF) of ischemic
origin at the background of therapy with simvastatin.
MATERIAL AND METHODS: We ex... |
27,160 | [Dynamics of QT interval dispersion in patients with ischemic heart disease
during stress test as possible reflection of changes of terminal part of the
T-wave]. | Changes of QT and QTa interval dispersion during stress test on treadmill and
possible dependence of these changes on results of stress test and severity of
coronary atherosclerosis were studied in 82 patients with effort angina. All
patients were subjected to stress test on treadmill and selective coronary
angiogr... |
27,161 | [Dobutamine stress-echocardiography in prognostication of risk of cardiovascular
complications in patients with atherosclerosis obliterans with forthcoming
surgery on the aorta and large arteries]. | Aim of the study was to analyze efficacy of the use of stress echocardiography
for assessment of degree of risk of cardiovascular complications in patients
with atherosclerosis obliterans of the aorta and large arteries of lower
extremities scheduled for surgery. Dobutamine-atropine stress echocardiography
was carr... |
27,162 | [Detection of left atrial auricular thrombus in patients with atrial
fibrillation and risk factors of thromboembolic complications: the role of
transesophageal echocardiography and multispiral computer tomography]. | Transesophageal echocardiography (TEE) is routinely used for visualization of
left auricular thrombi in patients with atrial fibrillation (AF). Multispiral
computed tomography (MSCT) with the use of contrast preparations is a novel
method of visualization of intracardiac structures. Forty three patients (27
men, 16... |
27,163 | [Effect of radiofrequency ablation of accessory atrio-ventricular junctions on
electromechanical coupling of the myocardium in children with manifesting
Wolf-Parkinson-White syndrome]. | Aim of the study was to assess immediate and remote hemodynamic and
electromechanical effects of radiofrequency ablation of accessory
atrio-ventricular pathways in children with manifesting Wolf-Parkinson-White
(WPW) syndrome. Radiofrequency ablation of accessory atrio-ventricular pathways
resulted in diminishment ... |
27,164 | [Cardiac natriuretic peptides in patients with hypertrophic cardiomyopathy]. | AIM: To study interrelation of main clinico-hemodynamic parameters and levels of
natriuretic peptides (NUP) in patients with hypertrophic cardiomyopathy (HCMP).
MATERIAL AND METHODS: We measured concentrations of N-terminal fragments of
precursors of plasma brain and atrial natriuretic peptides (NT-proBNP and
NT-pro... |
27,165 | [RELIPH--REgularnoye Letcheniye I ProPHylaktika (regular treatment and
prevention)--the key to improvement of situation with cardiovascular diseases in
Russia: results of multicenter study. Part I]. | The paper presents first results of the conducted in Russia large-scale study "
REgularnoye Letcheniye I ProPHylaktika (Regular Treatment and Prevention)--the
key to improvement of situation with cardiovascular diseases in Russia--RELIPH"
on assessment of conformity of recommended by medical practitioners treatment ... |
27,166 | [Age related changes of regulatory mechanisms of cardio-vascular system and
significance of nitric oxide synthase in the norm and pathology]. | The article sums up results of thirty-year period of studies of ontogenesis of
autonomic nervous system conducted in laboratory of neuromorphology and electron
microscopy. It contains discussion of pre- and postnatal ontogenesis of
cardiovascular innervation and content of NO-synthase in cardiac ganglia at
normal a... |
27,167 | [Antiatherogenic effects of angiotensin converting enzyme inhibitors from the
point of view of evidence based medicine]. | In a series of articles the authors analyze literature data concerning
controlled studies in which cardio-, cerebro-, and vasoprotective effects of
angiotensin converting enzyme inhibitors (ACEI) have been assessed. In the
second communication they discuss the results of three recently completed major
randomized pl... |
27,168 | [Von Willebrand factor and soluble P-selectin in patients with non ST-Elevation
acute coronary syndrome during treatment with glycoprotein IIb/IIIa antagonist
eptifibatide]. | Soluble P-selectin (marker of activation of platelets) and von Willebrand factor
(marker of activation of endothelium) were measured in 44 patients with non
ST-Elevation acute coronary syndrome (NSTEACS) 21 of whom received glycoprotein
IIb/IIIa antagonist eptifibatide (two 180 mg/kg boluses with 10 min interval
fo... |
27,169 | [Anxiety-depressive disorders in patients with type 2 diabetes mellitus
complicated with acute coronary syndrome]. | Psychological status of 140 patients with type 2 diabetes mellitus (DM) and
acute coronary syndrome (ACS) was studied on the 12-th day after the moment of
admission to the cardioreanimation department and in 6 months after discharge
from hospital. Spielberger questionnaire was used for assessment of level of
person... |
27,170 | [Immunoinflammatory factors in unstable angina. Possibility of influence of
atorvastatin]. | In 101 patients with ischemic heart disease (unstable angina class I and II-III)
with hypercholesterolemia at the background of standard therapy (51 patients)
and after administration of atorvastatin (50 persons) prescribed from first day
of hospitalization in mean dose 10.8 +/- 0.1 mg/day immune status was studied ... |
27,171 | [Prognostic value of parameters of diastolic left ventricular function and
muscular status in elderly patients - survivors of myocardial infarction]. | Aim of the study was to assess prognostic value of intraventricular filling
flows and parameters of muscular status in patients of elder age group who had
survived myocardial infarction. Patients (n=96) aged more than 60 years with
Q-wave myocardial infarction were subjected to echocardiographical examination
with ... |
27,172 | [Combined reperfusion in patients with acute myocardial infarction]. | Three schemes of treatment were used in the management of 230 patients with
acute myocardial infarction: immediate thrombolysis (group 1, n=71), immediate
thrombolysis followed by angioplasty in 12 hours-7 days depending of the
clinical picture of the disease (group 2, n=65), primary angioplasty not later
than 12 h... |
27,173 | [Effect of acenocoumarol and aspirin on platelet function, markers of
thrombinemia, and intracardiac thrombosis in patients with atrial fibrillation]. | Patients with atrial fibrillation taking either indirect anticoagulant
acenocumarol or most often prescribed antiaggregant aspirin were followed for 1
year. The results have shown that therapy with acenocumarol lowers content of
D-dimer, prevents formation and promotes lysis of left auricular thrombi and
lowers ris... |
27,174 | [A cross-sectional study of lipid metabolism in postmenopausal women]. | AIM: To assess frequency of atherogenic dyslipidemia in postmenopausal residents
of Ekateringurg.
METHODS: Cross-sectional study included 1100 female patients of outpatient
menopausal clinic. All were residents of Ekaterinburg aged from 28 to 64 years.
The participants of the study were divided into 3 groups; the 1s... |
27,175 | [Activity of lipid peroxidation and functional state of the myocardium in
remodeling of rat heart after experimental myocardial infarction]. | It was shown in experiments on Wistar rats that the processes of postinfarction
remodeling of the heart in animals that survived myocardial infarction were
characterized by lowering of excitability of cardiac muscle, impairment of
ability of sarcoplasmic reticulum to accumulate calcium ions. High level of
content o... |
27,176 | [Level of hormones of pituitary-gonadal axis, penile blood flow and sexual
function in men with arterial hypertension during monotherapy with bisoprolol
and nebivolol]. | Measurement of levels of hormones of the pituitary-gonadal system,
dopplerography of penile arteries and questioning after Vasiltchenko were
carried out in 30 men (age 35-55 years) with I-II degree arterial hypertension
who received monotherapy with bisoprolol and nebivolol for 2 months. Treatment
with both superse... |
27,177 | [Secular trends in blood lipid disorders among adolescents: population study in
Novosibirsk (1989-2003)]. | Hyperlipidemia is a known risk factor of coronary artery disease. The reduction
of elevated serum total cholesterol (TC) and low-density lipoprotein cholesterol
(LDL-C) levels in childhood may reduce cardiovascular morbidity and mortality in
adulthood. Aim of the study was to assess prevalence and trends in lipid pr... |
27,178 | [Pulmonary hypertension and right ventricular failure. Part X. Prostanoids in
the treatment of primary pulmonary arterial hypertension]. | In a series of articles the authors discuss literature data concerning
epidemiology of pulmonary arterial hypertension (PAH), its modern
classification; peculiarities of its pathogenesis and treatment in various
diseases and conditions. The tenth communication contains consideration of
results of controlled trials ... |
27,179 | [Perspectives of the use of antihyperglycemic preparations in patients with
metabolic syndrome and prediabetes]. | The state of prediabetes comprises two types of impairment of carbohydrate
metabolism: impaired fasting glycemia and impaired glucose tolerance. According
to International Diabetes Federation at present number of patients with
prediabtes is almost 2 times greater than that of patients with diabetes. Risk
of develop... |
27,180 | [Safety of magnetic resonance imaging after coronary stenting]. | Magnetic resonance imaging (MRI) is contraindicated to some patients with
certain types of metallic devices and implants (e.g. cerebral surgical clips,
defibrillators). There are some controversies concerning safety of MRI in
patients with metallic coronary stents in cases when MRI examination is
performed earlier ... |
27,181 | [Current approaches to echocardiographic assessment of systolic function of the
heart]. | Among modern methods of visualization of the heart echocardiography is most
often used for assessment of systolic function of the heart. The reasons for
this are noninvasive character of investigation, absence of ionizing radiation,
quickness of carrying out, availability and wide dissemination of
echocardiography.... |
27,182 | [Novel diagnostic possibilities of transesophageal stress echocardiography with
electrical atrial pacing]. | In order to develop simple technique of combination of transesophageal
echocardiography (TEE) and transesophageal pacing, to create algorithm and
protocol of transesophageal stress-echocardiography, and to study possible
complications and methods of their elimination we examined 39 subjects (mean age
50 +/- 7.2 yea... |
27,183 | [Comparative characteristics of intervals Q-T and J-T in patients with unstable
angina and myocardial infarction based on standard electrocardiography and
electrocardiotopography]. | We examined 94 patients (mean age 61,7 +/- 9,9 years) with unstable angina and
myocardial infarction. Comparative characterization of prognostic value of Q-T
and J-T intervals obtained at conventional 12-lead electrocardiography and
35-lead electrocardiotopography in assessment of risk of repetitive coronary
events... |
27,184 | [Correction of episodes of transitory myocardial ischemia with trimetazidine in
patients with ischemic heart disease combined with type 2 diabetes mellitus]. | Data of treatment of 45 patients with stable angina combined with type 2
diabetes mellitus are presented. Supplementation of standard anti-ischemic
therapy with cytoprotective preparation trimetazidine MB (Preductal MB) revealed
greater efficacy of treatment manifesting not only by decrease of functional
class in o... |
27,185 | [Recurrent myocardial infarctions: specific changes in biomarkers and in
myocardial remodeling (case-control study)]. | Basing on a case-control study (n=81) with the use of standard methods of
myocardial infarction verification, examination of hemogram, troponin T,
C-reactive protein, echocardiography data it was established that markers of
myocardial infarction (troponin T level) and inflammation (C reactive protein
level, lymphop... |
27,186 | [Genetic risk factors for development of myocardial infarction in young men
living in North-West region of Russia]. | With the aim to detect genetic factors of risk of development of early
myocardial infarction (MI) we studied 29 allele variants of 19 genes in 206 men
who had survived MI in the age before 45 years and in 195 men of similar age
without cardiovascular diseases. All subjects were inhabitants of North-West
region of R... |
27,187 | [PRIVILEGIYA (Privilege) study - Prestarium in the treatment of arterial
hypertension: antihypertensive effectiveness and safety in comparison with
enalapril]. | Collaborators: Sulim IuN, Kichigina OA, Kalabushkina NA, Kuziakina MV, Savinkin
AIu, Mamuchashvili VG, Shcherbakova NA, Pankratova EK, Agarkov EF, Zubanova IuN,
Pavlova ML, Lomteva SP, Pepelysheva TA, Shlaganova AA, Svidova NS, Tukanova LV,
Pankratova TM, Golubeva OB, Polovnikova TV, Chernozemova AV, Belkina NM,
Ga... |
27,188 | [Prediction of results of antiarrhythmic drug therapy in patients with malignant
ventricular tachyarrhythmias, based on the prognostic value of left ventricular
contractility parameters]. | In 44 patients (3 women and 41 men, mean age 54 +/- 11 years) with malignant
ventricular tachyarrhythmias (MVT) we assessed dependence of results of testing
of antiarrhythmic drugs and efficacy of their long term use for prevention of
recurrences of MVT on topography of derangement of local left ventricular (LV)
co... |
27,189 | [Drug-eluting stent thrombosis and its pharmacological prevention]. | The problem of drug eluting stents (DES) safety has been actively discussed
throughout 2006 because of increase of frequency of development of late stent
thromboses which were noted during almost 2 years after stenting. In December
2006 US Food and Drug Administration (FDA) advisory panel acknowledged increase
of d... |
27,190 | [Pulmonary hypertension and right ventricular failure. Part XI. Endothelin
receptor blockers in the treatment of primary pulmonary arterial hypertension]. | In a series of articles the authors discuss literature data concerning
epidemiology of pulmonary arterial hypertension (PAH), its current
classification; peculiarities of its pathogenesis and treatment in various
diseases and conditions. In the eleventh communication the authors discuss
literature data related to t... |
27,191 | [Detection and surgical treatment of induced ventricular tachycardia in
postinfarction left ventricular aneurysm]. | A clinical case of a patient aged 56 years with postinfarction left ventricular
aneurysm not complicated with ventricular tachyarrhythmias is presented
electrophysiological investigation. Left ventricular aneurysmectomy supplemented
with endocardial cryodestruction was carried out. At electrophysiological
investiga... |
27,192 | [Effect of statin therapy on dynamics of vascular endothelial growth factor and
fibroblast growth factor in patients with ischemic heart disease]. | The aim of our study was to assess the influence of rosuvastatin on coronary
angiogenesis. 30 male patients with chronic coronary heart disease and total
cholesterol level > 5.2 mmol/l were treated with rosuvastatin 10 mg daily during
3 months. The serum level of total cholesterol (TC), LDL-cholesterol (LDL-C),
HDL... |
27,193 | [About dyslipidemic states characteristic for various forms of ischemic heart
disease and cerebrovascular damages]. | We examined 4 groups of patients younger than 70 years with atherosclerosis of
coronary and/or cerebral arteries. In 98 patients the disease began as acute
myocardial infarction, 65 patient from the very beginning suffered from angina
of effort, 33 had ischemic cerebral stroke, and in 26 dyscirculatory
encephalopat... |
27,194 | [Cholesterol and glucose levels belong to independent predictors of death and
hospitalizations in patients with chronic systolic heart failure]. | PURPOSE: To elucidate relationship of total cholesterol (TC) level to results of
follow-up of patients (pts) with systolic chronic heart failure (CHF).
METHODS: In a framework of various international and local trials we
prospectively followed up 130 patients (pts) with stable NYHA class II-IV HF and
ejection fracti... |
27,195 | [Effect of hemodialysis on parameters of heart failure in patients with chronic
heart disease]. | Clinical presentations of chronic heart failure (CHF) and structural-functional
changes of the myocardium were studied in 65 patients (29 men, 36 women, mean
age 43,1 +/- 11,1 years) with stage IV - V of chronic renal disease in the
predialysis period and during first year of programmed hemodialysis. According
to c... |
27,196 | [Dynamics of parameters of heart rate variability after radiofrequency ablation
in patients with paroxysmal supraventricular tachycardia: holter ECG monitoring
data]. | Changes of parameters of heart rate variability (HRV) in patients with
supraventricular tachycardia (SVT) immediately after radiofrequency ablation
(RFA) have been demonstrated earlier. However dynamics of HRV parameters after
RFA has not been sufficiently studied. For elucidation of dynamics of HRV
parameters in p... |
27,197 | [Diagnostic significance of some clinico-functional parameters in vasospastic
angina]. | In a clinical study we have compared rates of detection of clinico-functional
parameters in 24 patients with vasospastic angina (VA) with intact coronary
arteries and 40 patients with ischemic heart disease (IHD) with anatomical
stenoses of coronary arteries with the aim of formation of a complex of most
informativ... |
27,198 | [Prognosis of patients with Q wave myocardial infarction of inferior or anterior
localization]. | The aim of the study was to determine clinical and demographic features that are
significant for prognosis after the first-ever myocardial infarction (MI).
Kaunas men and women aged 25 - 64 years, admitted to Kaunas hospitals due to
their first-ever MI during 1983 - 1992 and with the first coded
electrocardiogram (... |
27,199 | [Effect of a fixed combination of perindopril and indapamide on 24-hour blood
pressure profile, morpho-functional parameters of the heart, heart rate
variability, functional state of the kidney, and quality of life in patients
with arterial hypertension combined with metabolic syndrome]. | Therapy with the use of a fixed combination of perindopril and indapamide was
prescribed to 22 patients with metabolic syndrome and I - II degree hypertension
for 16 weeks. Examination at baseline and after treatment included 24-hour blood
pressure (BP) monitoring, echocardiography, biochemical analysis of blood, st... |
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