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27,300 | [Molecular mechanisms of effects of rosuvastatin on systemic oxidative stress
and endogenous inflammation in patients with atherosclerosis]. | Aim of the study was to investigate peculiarities of effects of rosuvastatin on
the state of oxidative stress and endogenous inflammation in patients with
extensive atherosclerosis. Patients with extensive atherosclerosis included into
the study (n=46, mean age 56.5 +/- 2.2 years) were distributed to 2 equivalent
a... |
27,301 | [The influence of purine nucleotides and adenosine on bioelectrical activity of
bat (Pipistrellus nathusii) heart]. | The aim of work was to investigate effects of adenosine, AMP, GMP and ADP-ribose
on bioelectric activity of bat heart. Purine nucleotides decreased action
potential duration at level of 90% (APD90) repolarization in bat ventricular
myocardium. When preparation of right ventricle was paced with frequency of 6
Hz, AP... |
27,302 | [Mitochondrial energy conversion disturbance with decrease in ATP production as
a source of systemic arterial hypertension]. | This review deals with the cellular mechanisms underlying decreased energy
status documented in different tissues from experimental rat models of primary
and secondary hypertension as well as the involvement of these abnormalities in
the pathogenesis of the disease. Such analyses allow us to hypothesize that
dysfun... |
27,303 | [Pleiotropic effects of statins]. | Systematization of pleiotropic actions of statins is presented with special
stress on effects important for prevention of atherosclerotic diseases,
nonatherosclerotic cardiovascular diseases, and diseases of noncardiovascular
origin. Dependence of pleiotropic effects of statins on dose and duration of
administratio... |
27,304 | [Efficacy of an educational preventive technology in patients with stable angina
in ambulatory conditions]. | Aim of the study was to assess efficacy of educational technology--School for
patients with stable angina--in conditions of practical health care. We
randomized 100 patients with ischemic heart disease (IHD) and stable FC I-III
angina into 2 groups one of which went through learning in a School for patients
with IH... |
27,305 | [Heart rate variability dynamics during treatment of arterial hypertension]. | Investigation of the dynamics of heart rate variability (HRV) in
anti-hypertension therapy can facilitate the evaluation of the effectiveness of
treatment.
AIM OF INVESTIGATION: to compare anti-hypertension effect of monotherapy with
nebivolol and dilatrend with dynamics of HRV and the estimation of the state of
pa... |
27,306 | [The experience of the use of intracardiac echocardiography during puncture of
atrial septum]. | We analyzed results of 175 intracardiac ultrasound studies (ICUS) in 113 men
(mean age 54,6 +/- 11,0 years) and 62 women (mean age 49,7 +/- 8,9 years) with
atrial fibrillation (n=146) and WPW syndrome (n=29). ICUS was used for guidance
of catheters or electrodes from right to left atrium through atrial septum in
16... |
27,307 | [Prognostication of results of coronary artery bypass surgery in men living in
the North]. | We analyzed immediate and remote results of coronary artery bypass surgery and
prognostication of outcome of the intervention in dependence on various risk
factors in 576 men aged 29 - 71 years living in the North. We formed a model
with strong prognostic effect on lethal outcome during in-hospital postoperative
pe... |
27,308 | [Effect of nibentan on dispersion of repolarization of ventricular myocardium in
the rabbit]. | Among factors determining development of polymorphic ventricular tachycardia
torsades de pointes under influence of class III antiarrhythmic drugs great
value is attributed to enhanced heterogeneity of repolarization of ventricular
myocardium which can cause functional conduction blocks and development of
re-entry ... |
27,309 | [Index of myocardial injury CIIS and mortality of patients with chronic
obstructive pulmonary disease]. | Aim of the study was to assess informative power of the Cardiac Infarction
Injury Score (CIIS) in patients with chronic obstructive pulmonary disease
(COPD) to determine the role of CIIS in prognosis of death of patients with
COPD. We examined 124 patients with COPD and followed 76 of them for 4 years.
During follo... |
27,310 | [Interval training in patients with chronic heart failure]. | Training sessions with constant level of work load are most often used in
cardiological rehabilitation. They are beneficial in secondary prevention of
ischemic heart disease and to some or other extent are familiar to practical
physicians. At the same time interval training appearing as sequence of short
periods of... |
27,311 | [A case of spontaneous closure of left main coronary artery false aneurysm and
stent thrombosis 11 years after coronary artery stenting]. | This is the presentation of a case of formation of traumatic iatrogenic false
aneurysm of left main coronary artery and its spontaneous closure combined with
acute thrombosis of the stented segment of anterior interventricular artery
(AIA) 11 years after initial procedure. False aneurysm was a consequence of
dissec... |
27,312 | [Multiple abscessing of valvular apparatus of the heart in a patient with
secondary infectious endocarditis]. | Progressive growth of infectious endocarditis morbidity has been noted in the
world during recent 10 years. Among secondary forms of endocarditis rate of
congenital heart defects is 21%. According to data of M.K. Rybakova (2007) the
highest risk of development of infectious endocarditis (74%) is noted on
bicuspid a... |
27,313 | [Comparative assessment of antiinflammatory action of atorvastatin in ischemic
heart disease and rheumatoid arthritis]. | AIM: To assess dynamics of marker of inflammation (C-reactive protein - CRP) and
parameters of lipid metabolism at the background of 3-months course application
of 2 standard variants of therapy with atorvastatin (40 and 10 mg/day) in
patients with rheumatoid arthritis (RA) compared with patients with ischemic
hear... |
27,314 | [Novel possibilities in the treatment of patients with heart failure. The method
of external counterpulsation]. | AIM OF THE WORK: To assess effect of programmed external counterpulsation (ECP)
on clinico-functional status, quality of life of patients with chronic heart
failure (CHF) of ischemic origin, stable functional class (FC) II-IV angina
refractory to drug therapy.
MATERIAL AND METHODS: Patients (n=30) with ischemic hear... |
27,315 | [Effect of strict glycemic control on clinical state and course of the disease
in patients with chronic heart failure and type II diabetes mellitus. Results of
the REMBO "rational effective multicomponent therapy in the struggle against
diabetes mellitus in patients with congestive heart failure" study]. | With the aim to investigate influence of glycemic control on clinical state and
course of disease, renal function, and neurohormonal profile of patients with
chronic heart failure (CHF) and type 2 diabetes mellitus (DM) we studied 81
patients with NYHA functional class (FC) II - III CHF, left ventricular ejection
f... |
27,316 | [Effect of perindopril on cognitive functions in young and middle aged patients
with hypertensive disease]. | We studied 40 men aged 26 - 59 years (mean age 49.0 +/- 1.9 years) with
hypertensive disease (HD) and found that therapy based on the use of angiotensin
converting enzyme inhibitor perindopril in young and middle aged patients with
stage I and II HD appeared to be not only one of effective methods of correction
of ... |
27,317 | [Gene expression analysis in myocytes of right atrial appendages in patients
with atrial fibrillation using cDNA microarray technique]. | Gene expression level of 2900 genes was studied by cDNA microarray in patients
with atrial fibril-lation (AF) or sinus rhythm. Gene transcripts were analysed
in samples of right atrial appendages from 47 patients undergoing surgery for
valve repair or coronary artery bypass. Standard correlation analysis and two
di... |
27,318 | [Guidelines of the American College of Cardiology/American Heart Association
2007 for the Management of Patients With Unstable Angina/Non-ST-Elevation
Myocardial Infarction. Part VI]. | This is the sixth part of translation of Guidelines of the American College of
Cardiology/American Heart Association 2007 for the Management of Patients With
Unstable Angina/Non-ST-Elevation Myocardial Infarction. The present Guidelines
represent a revision of ACC/AHA 2002 Guideline Update for the Management of
Pat... |
27,319 | [Effect of hypotensive drugs on painless ischemia of the myocardium and
diastolic function of the left ventricle]. | Aim of the study was comparative assessment of hypotensive, antiischemic
efficacy and effect on left ventricular (LV) diastolic function of calcium
antagonists, angiotensin converting enzyme inhibitor and blockers of
beta-adrenoreceptors.
RESULTS: The data obtained evidence that at monotherapy most pronounced loweri... |
27,320 | [Vegetative disturbances and dysfunction of the endothelium in patients with
postinfarction cardiosclerosis]. | We assessed vegetative status and parameters of endothelial function in 53
patients with postinfarction cardiosclerosis. Balance of autonomic nervous
system was characterized by the Kerdo index and heart rate variability at Holter
monitoring, endothelial function - by quantity of desquamated endotheliocytes in
bloo... |
27,321 | [Dynamics of pulse pressure in orthostatic test: interrelationships with risk
factors and involvement of the heart and vessels in elderly patients with
arterial hypertension]. | We studied dynamics of arterial pulse pressure (APP) during active orthostatic
test (AOT) in relation to cardiac and vascular involvement in 198 elderly
patients with arterial hypertension. We measured and compared parameters of
hemodynamics, rate of detection of risk factors, signs of affection of the heart
and ve... |
27,322 | [Assessment of total cardiovascular risk in adult persons of able-bodied age:
lessons of the CROSSWORD study]. | AIM: To assess level of total risk of cardiovascular diseases (CVD) in a cohort
of adults of ablebodied age and to study peculiarities of main risk factors (RF)
and their combinations in subjects with different total risk of CVD.
METHODS: In CROSSWORD (assessment of total cardiovascular risk in adult persons
of able... |
27,323 | [Possibility of optimization of hypertension control in operators of trains on
the basis of automatic system of pre-work examination]. | We have investigated possibility of the use of automatic systems for controlling
arterial pressure in a specific occupational group - train\'s operators. This
method is based on measurement and analysis of parameters of arterial pressure
and pulse during pre-work (pre-haul) medical examinations of train\'s operators... |
27,324 | [Identification of pacemaker cells from atrial natriuretic peptide expressing
embryonic stem cells]. | At present there exists a limited understanding of mechanisms of differentiation
and specialization of cardiac conduction system in mammals. For characterization
of its development and differentiation on early stages we used as experimental
model murine embryonic stem cells expressing enhanced green fluorescent prot... |
27,325 | [Comparative assessment of inotropic reaction of isolated myocardium of patients
with ischemic and rheumatic heart disease after short-term periods of rest at
the background of amiodarone]. | We studied inotropic reaction of isolated myocardium of patients with heart
failure induced by ischemic and rheumatic cardiac involvement after periods of
rest at the background of amiodarone. The studies were carried out on muscular
trabeculi separated from right atrial auricle during surgery. It was shown that
in... |
27,326 | [Takotsubo cardiomyopathy: origin and variants]. | This literature review is devoted to the " tako-tsubo " cardiomyopathy - rare
type of cardiomyopathy characterized by transient myocardial stunning. In acute
phase the disease resembles myocardial infarction. However no involvement of
coronary arteries is found at angiography. Echocardiography and ventriculography
... |
27,327 | [Connective tissue dysplasia, magnesium, and nucleotide polymorphisms]. | Undifferentiated connective tissue dysplasia (UCTD) is one of most common
diseases of the connective tissue. High frequency of UCTD in population along
with the fact that it can provoke a number of other diseases make UCTD an
important object of the modern biomedical research in the areas of cardiology,
neurology, ... |
27,328 | [Myxoma of the cor triatriatum]. | We present a rare case of myxoma in a patient with cor triatriatum. This
pathology was symptomless and was revealed at transthoracic echocardiographic
examination in a patient with ischemic heart disease. The patient was
successfully subjected to surgery which consisted in removal of the tumor
together with accesso... |
27,329 | [Disproportionately high left ventricular myocardial mass in patients with
arterial hypertension]. | BACKGROUND: Increase of myocardial mass of left ventricle (MMLV) to a greater
extent than required by hemodynamic load by elevated arterial pressure (AP) is
reflected in concepts of " disproportionately " high (DH) MMLV and resistant to
antihypertensive treatment LV hypertrophy (LVH).
AIM: To study in patients with ... |
27,330 | [Genetic aspects of development of microalbuminuria in patients with
hypertensive disease]. | Aim of the study was to investigate association of gene candidate polymorphisms
encoding elements of the renin-angiotensin system and participating in
regulation of vascular tone with development of microalbuminuria in patients
with hypertensive disease. We examined 93 patients (52 women, 41 men, mean age
58.3+/-1.... |
27,331 | [Metabolic peculiarities of dyslipoproteinemias unrelated to high level of blood
cholesterol]. | The aim of this study was to reveal whether atherogenic or nonatherogenic
properties of dyslipoproteinemias (DLP) not related to high level of blood total
cholesterol (C) and low density lipoprotein C (LDL C) are determined only by
shifts in serum triglycerides (TG) and/or high density lipoprotein cholesterol
(HDL ... |
27,332 | [Influence of ADP-ribose, AMP and adenosine on bioelectric activity of
hibernating ground squirrel atrium and papillary muscle]. | The aim of work was to investigate effects of adenosine, AMP and ADP-ribose
(1x10(-5)) on bioelectric activity of atrium and papillary muscle of
nonhibernating (rat) and hibernating (Yakutian ground squirrel) animals. Action
potential (AP) was registered with use of standard microelectrode technique. AP
duration (A... |
27,333 | [The use of angiotensin converting enzyme inhibitors in patients after
myocardial infarction]. | Nowadays angiotensin-converting enzyme inhibitors (ACE-Is) are considered to be
a cornerstone in the treatment of congestive heart failure (CHF). These agents
have been shown to improve survival and functional status of patients with CHF.
It is logical to start therapy with ACE-Is in the first hours or days of acute... |
27,334 | [Arterial hypertension in persons older than 80 years: the problem can be
successfully solved]. | It has been noted in recommendations of the European Society of Hypertension
(ESH) and of the European Society of Cardiology (2007) that there are no data on
effects of antihypertensive therapy on risk of development of cardiovascular
complications in patients older than 80 years. In the recently completed study
HY... |
27,335 | [Significance of stress echocardiography in patients with angiographically
intact coronary arteries]. | With the aim of assessment of the significance of stress echocardiography in
patients with unchanged coronary arteries we analyzed data from 75 patients in
whom coronary angiography (CAG) detected no hemodynamically significant
narrowing of coronary arteries. In 38 patients coronary syndrome X (CSX) was
revealed. I... |
27,336 | [Economics of nephroprotection in arterial hypertension and type 2 diabetes
mellitus]. | Based on results of large-scale controlled trials of irbesartan (I), valsartan
(V) and amlodipine (A) (PRIME and MARVAL) we carried out the Markov s modeling
of their pharmacoeconomic parameters in arterial hypertension (AH) combined with
diabetes mellitus type 2 (DM 2) and microalbuminuria (MAU) projected for 8-yea... |
27,337 | [Adiponectin: lowering in metabolic syndrome and independent relation to
hypertriglyceridemia]. | Aim of the study was to elucidate possible role of adiponectin in development of
clinico-metabolic derangements in metabolic syndrome (MS). We examined 35 men
and 45 women (mean age 58.0+/-8.8 years). Adiponectin level was significantly
lower (p<0.01) in patients with MS (5.8+/-4.6) compared with subjects without MS... |
27,338 | [Initial experience in Russia of excimer laser extraction of endocardial leads]. | PURPOSE: To assess effectiveness and safety of excimer laser extraction of
chronically implanted transvenous pacing leads using countertraction technique.
We operated upon 10 patients (female 2), mean age 56.1+/-11.7 years. Average
time of lead placement was 7.7+/-4.2 years. Indications included erosion of
device p... |
27,339 | [Spatiotemporal characteristics of activation of the heart of hibernating and
non-hibernating mammals during hypothermia]. | The heart of hibernating mammals is known to demonstrate the nature\'s model of
resistance to rhythm disturbances, including ventricular arrhythmias, during
hypothermia. However, electrophysiological mechanism of this phenomenon is not
completely understood. Using optical mapping technique with voltage-sensitive
dy... |
27,340 | [Protective effect of lornoxicam on development of myocardial infarction in rats
under conditions of ischemia and ischemia-reperfusion]. | Activation of inflammation and enzyme cyclooxygenase with formation of
proinflammatory prostaglandins is a key element of development of myocardial
infarction in patients with acute coronary syndrome. Basing on literature data
and own experience we suggested that single intravenous injection of 230 mg/kg
of nonsele... |
27,341 | [Coronary angioplasty in diabetic patients]. | The authors present a review of clinical studies conducted and completed in
2001-2005. The review contains data on clinical trials of sirolimus- and
paclitaxel-eluting stents in patients with diabetes mellitus and coronary artery
disease. The authors analyze experimental data on mechanism of neointima
formation in ... |
27,342 | [The role of inflammatory factors in pathogenesis of ischemic heart disease]. | PURPOSE: To study mechanisms of immune derangements in coronary heart disease
(CHD).
MATERIAL AND METHODS: We measured basic markers of immune activation in 43
patients with CHD and NYHA I-IV class heart failure (HF). There were 41 men and
2 women aged 33 - 64 years (mean 48 +/- 8 years). Concentrations of hsCRP, Ig... |
27,343 | [Assessment of the course of ischemic heart disease after placement of stents
with drug covering and uncovered metal stents: data of 3 years follow-up]. | The placement of sirolimus-eluting stents decreases the frequency of repeat
revascularization procedures in patients undergoing percutaneous coronary
intervention (PCI) in randomized clinical trials. However, there is uncertainty
about the effectiveness of sirolimus-eluting stents, and increasing concern
about thei... |
27,344 | [Prognostic value of atrial fibrillation in patients--survivors of acute
coronary syndrome]. | For the study of contribution of atrial fibrillation (AF) during acute coronary
syndrome (ACS) in long-term prognosis after clinical stabilization we examined
453 patients admitted to Moscow hospitals and followed them for 2.07 +/- 0.48
years. The following events were registered: fatal and nonfatal myocardial
infa... |
27,345 | [Admission and predischarge levels of NT pre brain natriuretic peptide in
patients hospitalized because of worsening heart failure. relation to risk of
death in the next 6-12 months]. | Inhospital treatment of patients with heart failure (HF) can cause changes of
N-terminal pro-brain natriuretic peptide (NT proBNP) levels. It has not been
established yet which NT proBNP value (before or at height of treatment
activation) is closer related to prognosis of unfavorable outcome after
discharge.
AIM: T... |
27,346 | [Radiofrequency ablation of chronic atrial fibrillation by combined isolation of
pulmonary veins and anatomical modification of arrhythmia substrate]. | Primary procedure of radiofrequency ablation (RFA) of chronic atrial
fibrillation (AF) using nonfluoroscopic mapping system was carried out in 49
patients (mean age 52.2 +/- 11.3 years, 6 women). Etiology of AF was coronary
artery disease, cardiosclerosis after myocarditis, dilated cardiomyopathy in 32,
11 and 2 pa... |
27,347 | [The study of effects of a novel acetylcholinesterase inhibitor on electrical
activity of the heart]. | We have investigated effect of a representative of the novel class of selective
acetylcholinesterase inhibitors A 1,3-bis[5(diethyl-o-nitrobenzyl ammonio)
penthyl]-6-methyluracildibromide (compound 547) on duration and rhythm of
sequence of right atrial action potential (AP) as well as on kinetics of
acetylcholines... |
27,348 | [The role of adiponectin in development and progression of cardiovascular
diseases]. | Arterial hypertension, insulin resistance, diabetes mellitus are associated with
obesity. However exact mechanisms of this association have not been determined
yet. Biologically active substances produced by adipose tissue participate in
pathogenesis of cardiovascular diseases and complications. In this review we
p... |
27,349 | [Clinical value of the study of stiffness of arterial wall. Part I]. | In this review we present concise historical background of formation of the
interest to investigation of properties of arterial wall in this review. We
consider in detail interrelation of arterial functions with their structure,
main mechanisms of action of elastic properties of arteries on systemic
hemodynamics. D... |
27,350 | [Diagnosis of malignant pericardial mesothelioma]. | Continuing growth of rate of detection of primary tumors of the heart has been
noted recently. Prevalence of cardiac tumors in European population according to
data of different authors varies from 25 to 5500 cases per 1 million of
autopsies. Malignant mesothelioma belongs to most rarely met tumors. In most
cases p... |
27,351 | [Immune mechanisms of inflammation in dilated cardiomyopathy]. | AIM: To study immune mechanisms of inflammation in dilated cardiomyopathy (DCM).
MATERIALS AND METHODS: The study of main markers of immune activation was
conducted in 44 patients with DCM with stage I - IIB and NYHA functional class
(FC) I - IV chronic heart failure (CHF). Among them there were 42 men (95%) and
2 w... |
27,352 | [Rosuvastatin and fenofibrate in patients with diabetes and low high density
lipoprotein cholesterol: comparison of changes of lipid levels and some markers
of inflammation]. | PURPOSE: To compare lipid lowering profile and effects on markers of
inflammation of rosuvastatin and fenofibrate in patients with type 2 diabetes
with low high density lipoprotein (HDL) cholesterol (CH).
METHODS: We enrolled into randomized open comparative study 30 pts (20 women)
aged 62.5 +/- 7.2 (47-74) years wi... |
27,353 | [Clinical-pharmacoeconomic aspects of trimetazidine modified release use in
patients with ischemic heart disease undergoing coronary artery bypass
grafting]. | The aim of this study was to evaluate clinical and pharmacoeconomic effects of
long-term use of trimetazidine MR in patients with ischemic heart disease (IHD)
undergoing coronary artery bypass grafting (CABG). Patients with IHD (n=306)
were included in open, prospective, randomized clinical trial. One group (group
... |
27,354 | [Stenting of unprotected left main coronary artery: complications during 3 years
follow up]. | Aim of investigation was to study complications during 3 years follow up of
patients after implantation of standard metal stents (SMS) in unprotected left
main coronary artery (LMCA). Patients with high risk of surgery (n=124) with
stenting of unprotected LMCA performed between August 2002 and November 2004
were in... |
27,355 | [Effect of hypotensive therapy on metalloproteinase activity of the blood in
patients with arterial hypertension]. | Aim of the study--investigation of dynamics of levels of serum markers of
myocardial fibrosis matrix metalloproteinase-1 (MMP-1), tissue inhibitor of
matrix metalloproteinase-1 (TIMP-1)--at the background of 3 months hypotensive
therapy in 39 patients with arterial hypertension and paroxysmal form of atrial
fibrill... |
27,356 | [Prevalence and predictors of masked inefficacy of treatment of arterial
hypertension during use of various groups of antihypertensive drugs]. | Prevalence and predictors of masked arterial hypertension (AH) in patients
receiving antihypertensive therapy (concealed treatment inefficacy--CTI) was
studied on material of data base comprising 219 observations. Drugs from 5
groups were used. Prevalence of CTI AH with the use of various definitions was
8.1-17.4%.... |
27,357 | [Association of genetic factors with clinical peculiarities of hypertensive
disease in patients with burdened familial anamnesis]. | With the aim to investigate association of polymorphisms of candidate genes with
clinical peculiarities of hypertensive disease in patients having burdened
familial anamnesis we examined 413 (229 men and 184 women, mean age 60.3 +/-
0.59 years) patients with essential arterial hypertension (AH). Determination of
al... |
27,358 | [The process of remodeling of left chambers of the heart and dysfunction of
endothelium of peripheral vessels in hypertensive premenopausal women]. | Results of ultrasound study of 230 premenopausal women with I-II stage essential
hypertension (EH) in relation to functional state of endothelium of peripheral
arteries are presented. Endothelial dysfunction in hypertensive premenopausal
women can be one of factors contributing to remodeling of left cardiac chamber.... |
27,359 | [Epidemiological studies as an instrument for assessment of society welfare and
quality of medical service (examplified by of analysis of myocardial infarction
morbidity)]. | Dynamics of incidence of myocardial infarction among adult (older than 20 years)
population of Seversk in 1998-2006 was studied according to WHO program
"Myocardial Infarction Register" updated in concordance with criteria of Joint
European Society of Cardiology/American College of Cardiology Committee for the
Rede... |
27,360 | [Effects of insulin and acidosis on metabolism and function of postischemic rat
heart]. | Isolated perfused hearts of male Wistar rats were subjected to 25-min
normothermic (37 degrees C) global ischemia, then 5-min infusion of a modified
perfusate (pH=7.4) and 25-min reperfusion (control). Experimental groups were
treated after ischemia with: a perfusate of the same composition (pH=6.0, RA), a
perfusat... |
27,361 | [Implantable cardioverters-defibrillators: prevention of sudden death]. | The paper is devoted to review of results of clinical application of implantable
cardioverters-defibrillators (ICD) as a method of prevention of sudden cardiac
death (SCD). In this work definition, epidemiology, mechanism, and nosological
causes of SCD are presented, followed by historical review of development of
... |
27,362 | [Pressor modification of pacemaker stress-echocardiograghy with the use of
moderate diagnostic doses of dobutamine]. | Supplementary infusion of moderate doses of dobutamine is proposed for obtaining
inotropic hyperkinetic response in the process of pacemaker stress
echocardiography with transesophageal electrical atrial pacing. With the aim of
approbation of technology and assessment of diagnostic reliability of the
suggested comb... |
27,363 | [Peculiarities of variability of complex of parameters of hemodynamics in
patients with arterial hypertension]. | We carried out spectral analysis of variability of 6 parameters of hemodynamics
(cardiac rhythm, stroke volume, ejection fraction, amplitude of pulsation of the
aorta, amplitude of pulsation of microvessels of foot, systolic arterial
pressure). We created a classification of oscillatory activity of these
parameters... |
27,364 | [Combination therapy of arterial hypertension combined with liver pathology. The
place of angiotensin converting enzyme inhibitors]. | It is necessary to take into account presence of concomitant pathology while
prescribing hypotensive therapy to patients with arterial hypertension (AH).
Hydrophilic angiotensin converting enzyme inhibitors (ACEI) (lisinopril) which
are not metabolized in the liver are theoretically safest in liver cirrhosis. We
ha... |
27,365 | [Echocardiographic evaluation in patients with idiopathic ventricular
arrhythmias originating from right ventricular outflow tract before and one year
after radiofrequency catheter ablation]. | PURPOSE: To estimate echocardiographic measurements in patients with idiopathic
ventricular arrhythmias originating from right ventricular outflow tract (RVOT)
before and one year after radiofrequency ablation (RFA) comparing with healthy
volunteers.
MATERIALS AND METHODS: The study consisted of 30 patients (7 women... |
27,366 | [Genetics of atrial fibrillation]. | We carried out examination of 103 probands with atrial fibrillation (AF) and 301
their 1st, 2nd, and 3rd degree relatives (main group). In addition we examined
82 probands without clinical electrocardiographic signs of heart disease and 163
their 1st and 2nd degree relatives (control group). We found accumulation of... |
27,367 | [Physical training at ambulatory-polyclinical stage in complex rehabilitation
and secondary prevention of patients with ischemic heart disease after acute
incidents. Effect on physical working capacity, hemodynamics, blood lipids,
clinical course and prognosis (Russian cooperative study)]. | AIM: To investigate efficacy of early and long term physical training (PT) of
moderate intensity in conditions of practical health care in Russia in patients
with ischemic heart disease (IHD) of able to work age - survivors of acute
coronary events.
MATERIAL AND METHODS: Three hundred ninety two patients were enroll... |
27,368 | [Changes of activation sequence in a rabbit sinoatrial node induced by
cholinergic influences]. | We used high resolution optical mapping for the study of activation sequence in
a rabbit sinoatrial node in normal state and during artificial stimulation as
well as changes of excitation chronotopography under cholinergic influences. In
the norm excitation originates in central region of sinoatrial node. During
ac... |
27,369 | [Hyperglycemia in patients with acute coronary syndrome: contemporary state of
the problem. A scientific statement from the American Heart Association diabetes
committee]. | Hyperglycemia in patients with acute coronary syndrome (ACS) is one of main
predictors of cardiovascular complications. Despite increasing number of proofs
of prognostic value of elevated glycemia in patients with ACS and lowering of
rate of clinical outcomes at the background of control of glycemia in patients
wit... |
27,370 | [Changes of the first electrocardiographic derivative in patients with ischemic
heart disease]. | Timely recognition of ischemic heart disease (IHD) is one of the main tasks of
cardiology. As a result the search for ways of early recognition of pathologic
changes of the myocardium is continuing. Analysis of the first
electrocardiographic derivative allows making more detailed assessment of
repolarization proces... |
27,371 | [Comparative characteristics of quality of life and physical status of patients
with ischemic heart disease and aortic valve disease]. | For comparison of physical status and quality of life of patients we analyzed 2
clinical groups: patients with ischemic heart disease (IHD) and aortic valve
disease. Using original methodology of bringing results of questionnaire "
Nottingham Health Profile " to functional classification we had a possibility to
com... |
27,372 | [Distributions of polymorphisms of genes of some components of hemostasis in
patients with ischemic heart disease]. | We have studied structure of polymorphisms of genes of blood clotting factors
II, V, VII, platelet membrane glycoprotein IIIa (GPIIIa) and enzyme
methylenetetrahydrofolate reductase (MTHFR) in patients with ischemic heart
disease (IHD). In this cohort of patients most prevalent are polymorphism
PLAA1/A2 of GPIIIa g... |
27,373 | [Antioxidant status and restenosis after stenting of coronary arteries]. | AIM: To investigate possibility of effect of antioxidant status on severity of
restenosis of coronary arteries after transluminal coronary angioplasty with
stenting.
MATERIAL AND METHODS: Men with ischemic heart disease and coronary angiography
performed in 6 months after coronary artery stenting with bare stents we... |
27,374 | [Structure of risk factors, damages of target organs, and metabolic changes in
patients with arterial hypertension of various age groups]. | AIM of the study consisted in investigation of structure of risk factors and
pathological changes of morphological and functional parameters of
cardiovascular system, parameters of carbohydrate and lipid metabolism and their
relationship with arterial hypertension (AH) in age groups younger than 35
years, 35 - 55, ... |
27,375 | [Echocardiography and magnetic resonance tomography of the heart in diagnosis of
noncompaction of left ventricular myocardium]. | Left ventricular (LV) noncompaction (NC) is a rare form of cardiomyopathy which
initially was diagnosed by transthoracic echocardiography (EchoCG). This paper
presents description of 15 patients with diagnosis of LVNC. Aim of the study was
to compare results of EchoCG with data of magnetic resonance tomography (MRT)... |
27,376 | [The study of peculiarities of immunotropic action of statins in chronic heart
failure of various etiology]. | AIM: To study features of statin therapy in patients with heart failure (HF) of
different etiology on immune system.
MATERIAL AND METHODS: The basic markers of immune activation in 43 patients with
chronic heart disease (CHD) and HF in New York Heart Association (NYHA) class I
to IV were studied. Mine age was 48 +/-... |
27,377 | [Prevalence and structure of anemia in patients with chronic heart failure in a
therapeutic hospital]. | We carried out retrospective analysis of 219 case histories of patients with
chronic heart failure admitted to a general medical hospital. Anemia (hemoglobin
level below 130 g/l in men and below 120g/l in women) was found in 23.3% of
cases. Anemia was classified as iron deficiency in 23.5% and as B12 deficiency
in ... |
27,378 | [Atherosclerotic lesion of the vessels in patients with stable coronary artery
disease: relations with concentration of C-reactive protein]. | AIM: To study value of C reactive protein (CRP) in development of
atherosclerotic lesion of vascular wall and its relation to extent of
pathological process in patients with stable coronary artery disease.
MATERIAL AND METHODS: We studied 307 patients with stable coronary artery
disease (278 men, 29 women) aged 33 -... |
27,379 | [Sudden cardiac death and polymorphism of genes-candidates of cardiovascular
diseases]. | Aim of the study was to elucidate genetic markers associated with elevated risk
of sudden cardiac death (SCD). We collected autopsy material during 1999 - 2001
in a process of forensic medical pathologo-anatomical examination of corpses of
182 men who had died suddenly in Octyabrsky district of Novosibirsk in the ag... |
27,380 | [Polymorphism of ACE, angiotensin II, NO-synthase, estrogen receptor genes and
gender differences in their effects on development of cardiovascular pathology]. | Genetic factors determine resistance or susceptibility to development of many
cardiovascular diseases. The study of polymorphisms of gene candidayes is a
perpective approach in detection of risk and prognosis of outcomes of
cardiovascular diseases. Most studied with the help of proven base genes are:
ACE gene, angi... |
27,381 | [Thienopyridines in the treatment and prevention of cardiovascular diseases.
Part I. Ticlopidine]. | In a series of articles the authors consider clinical pharmacology and
experience of clinical application of blockers of platelet P2Y12 receptors, most
well known representatives of which ticlopidine and clopidogrel according to
chemical structure belong to thienopyridine derivatives. In the first
communication pha... |
27,382 | [Modern tendencies in the treatment of patients with high risk of development of
cardiovascular complications and intolerance to angiotensin converting enzyme
inhibitors: value of results of TRANSCEND trial for clinical practice]. | Clinical value of pharmacologic blockade of renin angiotensin aldosterone system
for deceleration of cardiovascular continuum is strongly proved. Up to 20% of
population is intolerant to ACE inhibitors. There are no strong evidences that
ACE inhibitors differ from angiotensin receptors blockers in influence on main ... |
27,383 | [Transection of secondary chordae of anterior mitral valve leaflet as a method
of correction of functional mitral insufficiency during resection of left
ventricular aneurism]. | Dominating factor of development of functional mitral insufficiency in patients
with ischemic heart disease and dilated cardiomyopathy is deformation of
atrioventricular valve leaflets due to traction by chordae apparatus. In
patients candidates for left ventricular reconstruction because of its
postinfarction aneu... |
27,384 | [Effect of various approaches to therapy with statins in high risk patients from
the point of view of vascular endothelium]. | In a framework of multicenter study ATLANTIKA in a group of patients we carried
out noninvasive ultrasound test of endothelium dependent vasodilatation (EDVD)
of brachial artery before and at the background of therapy with atorvastatin.
Aim of the study was to assess and compare effects of incremental (10-80 mg/day)... |
27,385 | [Effect of therapy with rosuvastatin on circulating endothelial progenitor cells
in patients with chronic heart failure]. | We assessed effect of therapy with HMG--CoA reductase inhibitor rosuvastatin on
the number of circulating hemopoietic stem CD34+, CD133+ cells in peripheral
blood of patients with systolic left ventricular dysfunction of ischemic
genesis. Number of circulating hemopoietic stem CD34+, CD133+ cells in patients
with c... |
27,386 | [Structural-functional peculiarities of the heart and survival of elderly
patients with chronic heart failure and left bundle branch block]. | AIM: To study structural-functional characteristics of the heart and survival of
elderly patients with chronic heart failure (CHF) and left bundle branch block
(LBBB).
MATERIAL AND METHODS: We examined and followed-up 108 patients aged 60-85 years
with NYHA class II-IV CHF with and without LBBB.
RESULTS: Patients of... |
27,387 | [Morphological prerequisites of heart ventricles fibrillation in sudden cardiac
death]. | We studied morphological changes in the myocardium and content of glucose,
magnesium, calcium, sodium in pericardial fluid of victims of out of hospital
sudden death due to acute coronary insufficiency and prenecrotic stage of
myocardial infarction. We established that both in regions of ischemic injury
appearing a... |
27,388 | [Effect of antihypertensive drugs on some humoral parameters of endothelial
function]. | We assessed effect of antihypertensive drugs from various classes on humoral
parameters of endothelial function - levels of asymmetrical dimethyl-arginine
(ADMA) and metabolites of nitrous oxide (MNO) - in 106 patients with I-II degree
arterial hypertension before and after 2 weeks of treatment. Two weeks treatment ... |
27,389 | [Comparative assessment of a calcium antagonist with controlled release of
nifedipine and enalapril in arterial hypertension in subjects older than 60
years]. | We compared antihypertensive effects and organoprotective action of a calcium
antagonist nifedipine RD and angiotensin converting enzyme (ACE) inhibitor
enalapril in subjects older than 60 years with systolic diastolic (group 1) and
isolated (group 2) I-II degree arterial hypertension. Subgroups of patients
receivi... |
27,390 | [Novel approaches to assessment of rehabilitative-preventive quality measures in
patients with ischemic heart disease]. | Cardiorehabilitation and secondary prevention in patients with ischemic heart
disease (IHD) are at present actively introduced in practical health care.
However problems of standardization of methods of cardiorehabilitation and
secondary prevention remain unsolved and criteria of efficacy of conducted
measures in p... |
27,391 | [Action of a nitric oxide donor dinitrosyl complex of iron with glutathione on
hemodynamics in rats and monkeys]. | We studied action of a nitric oxide donor, dinitrosyl complex of iron (DNIC)
with glutathione as a ligand on the hemodynamics of normotensive Wistar rats,
spontaneously hypertensive rats (SHR), and monkeys. Intravenous DNIC
introduction (2-120 mg/kg) rendered fast (1-2 min) hypotensive effect combined
with increase... |
27,392 | [Percutaneous coronary interventions on unprotected left main coronary artery:
contemporary outlook of the problem]. | Coronary bypass surgery in patients with lesions in unprotected left main
coronary artery (LMCA) remains gold standard of treatment. However there is a
tendency to more frequent use of percutaneous coronary interventions (PCI) in
patients with such lesions. Is PCI of LMCA justified, what is complication rate
of PCI... |
27,393 | [Safety and efficacy of the use of glycoprotein IIb/IIIa inhibitors in the
invasive treatment of patients with ST-elevation acute coronary syndrome]. | The purpose of the study was to estimate the safety and the efficacy of the use
of tirofiban, its influence on the function of the left ventricle of the heart
and the clinical outcome of the patients with ST elevation acute coronary
syndrome (ACS) during the rescue coronary angioplasty after the unsuccessful
thromb... |
27,394 | [Effective treatment of arterial hypertension in women reduces frequency of
calls for medical aid due to emergency indications. Data from the AFINA study]. | Results of the study of efficacy of 12 weeks antihypertensive therapy of women
with uncontrolled arterial hypertension (AH) in ambulatory conditions are
presented. It has been shown that therapy comprising controlled release
indapamide allows to achieve greater lowering of arterial pressure (AP) as well
as higher f... |
27,395 | [Professional stress and development of stress-induced hypertension]. | to elucidate rates of development of arterial hypertension (AH) at working place
(wp), risk factors of cardiovascular diseases (CVD), anxiety depressive
disorders in persons with professional stress. We carried out monitoring of
arterial pressure during working hours and hours of rest, assessed risk factors
of CVD ... |
27,396 | [Repetitive hospitalizations of patients with chronic heart failure according to
data of one year follow-up study]. | Patients with chronic heart failure (CHF) represent a group with high risk of
repetitive hospitalizations. In order to assess frequency of repetitive
hospitalizations and elucidate their risk factors we included in this study 962
patients with stage IIA-III and functional class II-IV CHF hospitalized in a
multiprof... |
27,397 | [Treatment of patients with long nocturnal asystoles and obstructive sleep apnea
syndrome by creating continuous positive air pressure in the upper respiratory
tract]. | AIM: To study prevalence of obstructive sleep apnea syndrome (OSAS) in patients
with nocturnal asystoles, and assess therapeutic efficiency of constant positive
air pressure (CPAP) applied to upper respiratory tract in this category of
patients.
METHODS: The study incorporated 37 patients (33 men and 4 women, averag... |
27,398 | [Changes in proinflammatory cytokine and destructive metalloproteinase levels
during formation of unstable atherosclerotic plaque]. | We studied men with coronary atherosclerosis without acute coronary syndrome and
determined typical valuable parameters of inflammatory (tumor necrotic factor,
antagonist of receptor to interleukin [IL] 1, IL 6, IL 8, monocytes chemotactic
protein 1, endothelial monocytes activating protein II), and destructive (mat... |
27,399 | [Changes in the activation sequence in the rabbit sinoatrial node induced by
adrenergic stimulation]. | We used high resolution optical mapping for the study of changes of activation
sequence of a rabbit sinoatrial node induced by adrenergic stimulation during
natural and paced rhythm. Activation of adrenoreceptors with isoproterenol (10,
100 nanoM, 1 microM) as well as stimulation of intramural postganglionic
sympat... |
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