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27,400 | [Alcohol septal ablation and prevention of sudden cardiac death in patients with
hypertrophic cardiomyopathy. A case report]. | We discuss approaches to the treatment of patients with hypertrophic
cardiomyopathy, problems of prevention of sudden cardiac death in subjects with
this pathology, and present results of multicenter study assessing efficacy of
cardioverter defibrillator implantation in patients with hypertrophic
cardiomyopathy. Sp... |
27,401 | [Registry of acute coronary syndromes RECORD. Characteristics of patients and
results of inhospital treatment]. | PURPOSE: As contemporary information on real life management of hospitalized
patients (pts) with acute coronary syndromes (ACS) in Russia is lacking we
initiated limited ACS registry using no financial and no or minimal
administrative support.
METHODS: REgistry of acute CORonary synDromes - RECORD is a
participants... |
27,402 | [The use of tirofiban in invasive treatment of patients with non-ST-elevation
acute coronary syndrome]. | The study assessed 123 patients with non-ST-elevation acute coronary syndrome
who were randomized into two groups: percutaneous coronary intervention (PCI)
(62 patients) and PCI against background of tirofiban injection (61 patients).
The results of the study were estimated during the early (up to 30 days) and the
... |
27,403 | [An experience of the use of stem cells in the treatment of patients with
myocardial infarction and low ejection fraction]. | We present our own experience of assessment of effect of cell therapy on
functional state of the myocardium in patients with lowered contractile capacity
of the left ventricular myocardium. Intracoronary administration of stem cells
in acute myocardial infarction is a safe method of treatment. It does not cause
add... |
27,404 | [Effect of angiotensin converting enzyme inhibitors on oxidative stress,
endothelial function in patients with myocardial infarction]. | We examined 50 patients with acute myocardial infarction (MI) who in dependence
on prescription in the content of basic therapy of sulfhydric group containing
angiotensin converting enzyme inhibitors (ACEI) zofenopril and captopril were
divided into 2 groups each comprizing 25 patients. We studied dynamics of lipid ... |
27,405 | [Efficacy of therapy with bisoprolol and ivabradine in patients with ischemic
heart disease combined with chronic obstructive pulmonary disease assessment of
parameters of 24-hour ECG monitoring]. | Effect of therapy with 1-adrenoblocker bisoprolol and inhibitor of If channels
ivabradine on parameters of 24-hour ECG monitoring (24hECGM) was studied in 64
patients with ischemic heart disease (stable angina) and chronic obstructive
pulmonary disease (COPD). At the first stage all patients received bisoprolol.
Pa... |
27,406 | [Right ventricular cardiac failure in hospitalized patients with chronic
obstructive pulmonary disease: prevalence and clinical and instrumental
characteristics]. | The prevalence of right ventricular cardiac failure (CF) and its characteristics
were analysed in 326 hospitalized elderly patients with chronic obstructive
pulmonary disease (COPD) (average age 70+/-11 years). At admission right
ventricular CF was diagnosed in 107 (33%) patients with COPD; its prevalence did
not d... |
27,407 | [Association of Sp4 gene polymorphism with pathological tortuosity of internal
carotid arteries]. | Aim of the study was identification of genes and their polymorphisms associated
with pathological tortuosity (PT) of internal carotid arteries (ICA) for
elucidation of etiological causes of this anomaly taking into consideration its
high prevalence and clinical significance. We invited for examination 61
families o... |
27,408 | [Efficacy and safety of bisoprolol in pregnant women with chronic arterial
hypertension do not depend on genetic CYP2D6 polymorphism]. | The investigation has been conducted with the aim of studying association
between polymorphic marker G1846A of CYP2D6 gene and efficacy and safety of
bisoprolol in 64 pregnant women with chronic stage I and II hypertension. These
women have been under observation during trimesters II and III of pregnancy.
Results o... |
27,409 | [Arterial hypertension, echocardiographically determined left ventricular
hypertrophy and N-terminal pro-B type natriuretic peptide levels in women
population aged 56-65 years]. | Aim of the study was to investigate relationship between arterial hypertension
(AH), left ventricular myocardial mass (LVMM), and levels of N-terminal pro-B
type natriuretic peptide (pro-NT BNP) in a population of women inhabitants of
Tallinn aged 56-65 years. Of 163 women aged 50-59 years who had participated in
e... |
27,410 | [Quality of life of patients with Wolff-Parkinson-White syndrome before and
during one year after radiofrequency catheter ablation of accessory pathways]. | The paper contains presentation of complex analysis of quality of life (QL) of
140 patients with Wolff-Parkinson-White (WPW) syndrome before and during one
year after radiofrequency catheter ablation (RFCA) of accessory pathways (AP) .
Assessment of QL was based on the use of nonspecific and specific
questionnaires... |
27,411 | [The use of beta-adrenoblockers in the treatment of arterial hypertension in
pregnant women]. | We reviewed literature on the application of beta-adrenoblockers for the
treatment of arterial hypertension during pregnancy. Decisions concerning
administration of various preparations from this group in pregnant women should
be taken with consideration of efficacy in correction of hypertension and safety
for fetu... |
27,412 | [Endothelial dysfunction and oxygen binding properties of hemoglobin]. | According to results of analysis of literature and carried out studies
endothelial dysfunction is associated with impaired formation of NO-derivatives
of hemoglobin. This affects not only NO release in various parts of vascular bed
but also affinity of hemoglobin to oxygen, and therefore optimal course of blood
oxy... |
27,413 | [Oxidized fibrinogen and its relationship with hemostasis disturbances and
endothelial dysfunction during coronary heart disease and myocardial
infarction]. | The highest oxidative modification of fibrinogen was found in acute myocardial
infarction (MI) men and it was 1.26 and 1.56 times higher in comparison with
coronary heart disease (CHD) men with anamnesis of MI and with men without CHD,
respectively. Increased oxidized fibrinogen level correlated with increased
leve... |
27,414 | [Factors associated with low ankle-brachial index in patients with type 2
diabetes and prediabetes]. | PURPOSE: To elucidate factors associated with an established marker of occlusive
atherosclerosis of lower extremities - low ankle-brachial index (ABI) - in
patients with diabetes mellitus or prediabetes.
METHODS: We examined 182 patients with diabetes (n=158), impaired glucose
tolerance (n=17), or impaired fasting g... |
27,415 | [Structural-functional changes of walls of common carotid and brachial arteries
in hypertensive disease and ischemic heart disease]. | With the help of ultrasound methods of investigation we carried out comparison
of structural-functional and hemodynamic properties of common carotid and
brachial arteries in patients with hypertensive disease (HD) including those
with concomitant ischemic heart disease (IHD) and in subjects of control group.
Patien... |
27,416 | [The use of atorvastatin in patients with rheumatoid arthritis with
hyperlipidemia]. | AIM: To assess efficacy and tolerability of atorvastatin and its lipid lowering
and antiinflammatory effects as well as action on function of endothelium and
elastic properties of arteries in patients with rheumatoid arthritis (RA) and
hyperlipidemia.
MATERIAL: Patients with RA (n=50) were divided into 2 groups. The... |
27,417 | [Comparative transcriptome analysis of human aorta atherosclerotic lesions and
peripheral blood leukocytes from essential hypertension patients]. | One of the major cardiovascular risk factor which predisposes to and accelerates
atherosclerosis is arterial hypertension (AH). To determine the molecular basis
of the crosslink between AH and atherosclerosis for the development of new
treatment strategies large-scale transcriptome analysis of the cells implicated
... |
27,418 | [Possibilities of dopplerography in assessment of functional state of the heart
in patients with arterial hypertension with impaired diastolic cardiac
function]. | The search for reliable Dopplerographic markers of incipient diastolic cardiac
failure became especially actual in recent years. We examined 71 patients with
II degree arterial hypertension (AH) with Dopplerographical signs of diastolic
left ventricular (LV) dysfunction. For the assessment of severity of diastolic
... |
27,419 | [Effect of arterial hypertension on sexual health of men and their quality of
life. Resuts of BOLERO study]. | Analysis of results of epidemiological BOLERO study showed that 2/3 of men with
uncontrolled arterial hypertension noted problems in sexual life. Severity of
problems in this sphere of life of men correlated positively with age, as well
as with presence of difficulties at work, increased fatigability, impossibility ... |
27,420 | [Disturbances of primary hemostasis in patients with dilation cardiomyopathy]. | We studied morphological characteristics of platelets and parameters of platelet
aggregation in patients with dilation cardiomyopathy. Augmented aggregatory
activity of platelets was found in 76% of patients. In blood of majority of
patients we found circulating leukocyte-platelet aggregates. This evidenced for
dev... |
27,421 | [Clinical and prognostic significance of left bundle branch block in patients
with severe chronic heart failure]. | Clinical and prognostic significance of left bundle branch block (LBBB) was
investigated in 62 elderly patients with severe chronic heart failure (CHF). In
comparison to 93 patients with CHF but without intra-ventricular blocks patients
with LBBB demonstrated more frequently atrial fibrillation and left ventricular ... |
27,422 | [Left bundle of his brunch block as a manifestation of the syndrome of
dromotropic insufficiency in patients with chronic heart failure]. | Left bundle brunch block (LBBB) is met in approximately 20% of hospitalized
patients and in 1/3 of outpatients with chronic heart failure (CHF).
Abnormalites of impulse conduction in LBBB promote dyssynchronization, which
represent a pathophysiological process which not only worsens ventricular
function but also fa... |
27,423 | [Diagnosis and treatment of disturbances of lipid metabolism in children and
adolescents]. | It has been demonstrated in prospective and epidemiological studies that
excessive consumption of saturated and trans-fats, refined carbohydrates,
epidemic of obesity and metabolic syndrome in children and adolescents have
prognostic value in relation to development of cardiovascular diseases (CVD) in
adults. Pedia... |
27,424 | [Heart rate and acute coronary syndrome: crosslink mechanisms and possibilities
of drug intervention]. | Studies in general population, in elderly people, and in groups of patients with
arterial hypertension, myocardial infarction, stable coronary heart disease,
diabetes mellitus, and after coronary bypass surgery have shown that elevated
heart rate (HR) is prognostically unfavorable factor of cardiovascular and total ... |
27,425 | [The efficacy of external counterpulsation depending on severity of coronary
artery lesion]. | The aim of our investigation was to assess the efficacy of enhanced external
counterpulsation (EECP) in ischemic heart disease (IHD) patients depending on
previous by-pass surgery. 30 IHD patients (pts) were treated with EECP using
standard protocol (35 hours, 1 hour each procedure). All patients were divided
into ... |
27,426 | [An experience of the use of a fixed atenolol amlodipine combination in real
clinical practice: results of multicenter Russian study]. | AIM: To assess clinical, hemodynamic efficacy and tolerability of a Fixed
Atenolol Amlodipine Combination (FAAC) in patients with arterial 1-3 degree
arterial hypertension as mono- or combination therapy.
MATERIAL AND METHODS: Antihypertensive efficacy and tolerability of FAAC was
investigated in open noncomparative... |
27,427 | [Prognostic value of plasma levels of N-terminal pro-brain natriuretic peptide
and proinflammatory cytokines in patients with heart failure of ischemic
etiology]. | We included 63 patients with chronic heart failure of ischemic origin (32 with
left ventricular ejection fraction less than 40%) into prospective study with
average duration of follow-up 27+/-10 months. Relative risk of lethal outcome
was significantly increased in patients with initial endsystolic left
ventricular... |
27,428 | [Holter monitoring in healthy children during first days of life]. | Aim of the study was to determine dynamics of main parameters of heart rhythm in
children during first days of life. Material and methods. We examined 30 healthy
newborns (14 boys and 16 girls) aged 1-4 days (2,6+/-1,3 days). Criteria of
inclusion were healthy mother, normal course of pregnancy and delivery,
gestat... |
27,429 | [Ser49gly polymorphism as predictor of development of hereditary sick sinus node
syndrome]. | We demonstrated for the first time on clinico-genetic material an association of
hereditary sick sinus node syndrome (SSNS) with polymorphism of
beta-adrenorecetor gene. We found that heterozygous variant of Ser49gly of
beta-adrenoreceptor gene was significantly more often met in patients with SSNS
and their health... |
27,430 | [Pathogenesis of myocardial hypoxia in patients with metabolic syndrome]. | Aims of the study were to determine main pathophysiologic mechanisms of
decreased exercise tolerance in patients with metabolic syndrome (MS); to prove
the state of hypoxemia by ergospirometry in patients with MS; to reveal with the
help of echocardiography lowering of functional activity of the myocardium in
MS; t... |
27,431 | [Normal values of temporal parameters of ECG in children according to results of
clinico-epidemiological study ECG-screening of children and adolescents in
Russian federation]. | In order to obtain reliable information about time-domain ECG parameters in
Russian children and to analyse their links with physiological changes the
Project "ECG screening of children and adolescents of the Russian Federation"
was carried out in 2003-2008. Time domain ECG parameters were studied in the
representa... |
27,432 | [Protective effect of mitochondrial antioxidant SkQl at cardiac ischemia and
reperfusion]. | Mitochondria are believed to be both main origin and target of oxidative stress
in cells. In the present study we used novel mitochondria-targeted antioxidant
SkQ1 using triphenylphosphonium cation as a driver. The substance was alimentary
given to rats daily during 3 weeks in varying doses, from 0.5 to 250 mol/kg/d... |
27,433 | [Wolff--Parkinson--White syndrome: classification, clinical manifestations,
diagnosis, and treatment]. | Main etiological factors, mechanisms of arrhythmogenesis, and classification of
Wolff-Parkinson-White (WPW) syndrome are presented and
clinico-electrocardiographical and electrophysiological peculiarities of
atrioventricular reciprocal tachycardia in this syndrome are described. Main
diagnostic measures, principles... |
27,434 | [Thienopyridines in the treatment and prevention of cardiovascular diseases.
Part II. Clinical pharmacology of clopidogrel]. | In a series of articles the authors consider clinical pharmacology and
experience of clinical application of blockers of platelet P2Y12 receptors, most
well known representatives of which ticlopidine and clopidogrel according to
chemical structure belong to thienopyridine derivatives. In the second
communication we... |
27,435 | [Value of telemetric support organization in prehospital management of patients
with myocardial infarction for delays shortening of thrombolytic therapy]. | Aim of the study was to assess efficacy of the use of telemetric support of
prehospital thrombolytic therapy (TLT) of myocardial infarction. We observed 206
patients with ST-elevation myocardial infarction (MI). These patients were
divided into 2 groups: in one TLT was initiated after admission to hospital, in
the ... |
27,436 | [Efficacy of strict glycemic control in first 24 hours of myocardial infarction
in patients with type 2 diabetes mellitus]. | The study evaluated the influence of strict glycemic control during first 24
hours of myocardial infarction on 6-months mortality and systolic function of
the left ventricle. Of 65 patients with type 2 diabetes mellitus and acute
myocardial infarction 30 received 24-hour infusion of short acting insulin and
35 serv... |
27,437 | [Provision of complex cardioprotection with the help of carvedilol in 1-2 degree
arterial hypertension combined with metabolic syndrome]. | In an open prospective 16-week study we carried out assessment of clinical
efficacy, vaso- and cardioprotective properties of nonselective alpha and
beta-adrenoblocker carvedilol used as monotherapy and in combination with
nifedipine or as combination of these drugs with metformin and simvastatin. We
have shown tha... |
27,438 | [Sudden out of hospital cardiac death in children, adolescents, and subjects
younger than 45 years]. | Aim of this study was determination of incidence and structure of sudden out of
hospital cardiac death (SCD) in subjects aged 1-45 years in Moscow. We analyzed
rate and structure of SD among persons who had succumbed in 2005-2007 in several
districts of Moscow with population of 2,502,836. Of the total number of 19,... |
27,439 | [Dietary SkQ1 supplement reduces myocardial ischemia- reperfusion injury in rats
in vivo]. | To examine whether nutritional supplementation with SkQ1 can reduce myocardial
ischemia-reperfusion injury in vivo, Wistar rats were fed a regular diet
supplemented with different doses of SkQ1 for two or three weeks. Control groups
of rats were fed the same diet supplemented with NaBr. Anaesthetized rats were
subj... |
27,440 | [Prevention and correction of cognitive disorders in arterial hypertension]. | In this review we systematized literature data illuminating problems of
prevention and correction of cognitive disorders in patients with arterial
hypertension (AH). On the basis of results of multicenter randomized studies we
have demonstrated close interrelationship between cardiac and cerebral pathology
and valu... |
27,441 | [The syndrome of mitral regurgitation in patients with chronic heart failure]. | Functional mitral regurgitation is a frequent complication of severe course of
ischemic heart disease and plays a role of no small importance in origin and
progression of chronic heart failure (CHF). Severe degree of mitral
regurgitation is found in 18.9%, moderate - in 29.7% of patients with systolic
left ventricu... |
27,442 | [Immediate and remote results after percutaneous transluminal coronary
angioplasty and coronary bypass surgery in patients with multivascular
involvement of coronary arteries]. | Relatively little time has passed since elaboration and introduction of coronary
angioplasty however interventional cardiology in these years has made a swift
leap in its development. Initially coronary interventions were carried out only
on isolated proximal stenoses but later interventions became to be performed o... |
27,443 | [Effect of myocardial revascularization on dynamics of factors of angiogenesis
in patients with ischemic heart disease]. | Aim of the study was to assess effect of myocardial revascularization on levels
of factors of angiogenesis in early and remote period after intervention. Main
group comprised 228 patients with ischemic heart disease (n=228, 194 men, 34
women, mean age 57+/-8.7 years). Coronary bypass surgery was carried out in 29
p... |
27,444 | [Effect of arterial stiffness on development of cardio-vascular complications in
ischemic heart disease]. | With the aim to assess effect of arterial wall stiffness on prognosis of
patients with stable form of ischemic heart disease (IHD) we included 224 men
(mean age 56.2+/-8.9 years) with confirmed IND in a long-term prospective study.
Pulse wave velocity was measured with brachial-ankle method (PWVba), presence of
lef... |
27,445 | [Reactions of sympatho-adrenal system in patients with ischemic heart disease
during emotional stress in dependence on the personality type]. | The object of the study was to show the relationship between emotional stress
and excitation of the sympathoadrenal system in healthy subjects and patients
with coronary heart disease (CHD). Seventy eight healthy subjects and 40 CHD
patients of the II-III functional class were under medical observation.
Emotional t... |
27,446 | [Phenotypes of arterial pressure in young men]. | AIM: To study with the use of repetitive clinical measurements and 24-hour
arterial pressure (AP) monitoring phenotypes of AP in young men aged 18-25 years
with history of elevation of AP at accidental determination.
MATERIAL AND METHODS: We examined 194 young men (mean age 21.1+/-2.1 years)
because of detection of ... |
27,447 | [N-terminal pro-brain natriuretic peptide and cardiac involvement in patients
with hypertensive disease]. | The purpose of this study was to define a correlation between N-terminal proBNP
level and extent of cardiac abnormalities. A total of 40 patients with
hypertension were included in the study (60.5+/-7.6 years of age; 18 men, 22
women). It was found that patients with hypertension had increased plasma
N-terminal pro... |
27,448 | [Aorto-coronary bypass grafting in patients with pronounced left ventricular
dysfunction: long-term results and value of detection of viable myocardium]. | Aim of the study was to investigate effect of volume of viable myocardium as
detected by stress-echocardiography on functional class and survival of patients
with pronounced left ventricular dysfunction after aorto-coronary bypass
grafting (ACBG). We made retrospective analysis of clinical and
echocardiographic dat... |
27,449 | [Effects of dinitrosyl iron complex on metabolism and cellular membranes in
ischemic rat heart]. | Effects of exogenous NO donor--dinitrosyl iron complex with reduced glutathione
(DNIC-GS) on functional recovery of isolated perfused rat heart subjected to
global ischemia and reperfusion have been studied. DNIC-GS administration after
ischemia substantially improved contractile and pump function recovery within a ... |
27,450 | [Intravascular ultrasound investigation with virtual hystology in the study of
coronary artery lesions]. | Spectral analysis of radiofrequency data obtained at intravascular ultrasound
study allows to carry out more detailed analysis and morphological assessment of
plaque components. In the course of preliminary investigations in vitro 4 types
of reflected signals were revealed. According to results of spectral analysis ... |
27,451 | [Thienopyridines in the treatment and prevention of cardiovascular diseases.
III. therapeutic application of clopidogrel as monotherapy (without
acetylsalicylic acid)]. | In a series of articles the authors consider clinical pharmacology and
experience of clinical application of blockers of platelet P2Y12 receptors, most
well known representatives of which ticlopidine and clopidogrel according to
chemical structure belong to thienopyridine derivatives. In the third
communication we ... |
27,452 | [Thienopyridines in the treatment and prevention of cardiovascular diseases.
Part IV. therapeutic application of clopidogrel in combination with
acetylsalicylic acid in acute coronary syndromes and percutaneous coronary
interventions]. | In a series of articles the authors consider clinical pharmacology and
experience of clinical application of blockers of platelet P2Y12 receptors, most
well known representatives of which ticlopidine and clopidogrel according to
chemical structure belong to thienopyridine derivatives. In the forth
communication we ... |
27,453 | [Adipose tissue inflammation and atherosclerosis]. | Adipose tissue is an endocrine organ secreting more than 30 various adipokines
which regulate wide spectrum of metabolic and immune processes. Obesity is
associated with development of adipose tissue inflammation. This inflammation is
characterized by infiltration with macrophages, alterations of adipokine
secretio... |
27,454 | [Mitral valve remodeling in patients with acute myocardial infarction and
ischemic mitral regurgitation]. | We have studied alterations of mitral valve geometry and quantitative parameters
of mitral regurgitation in 130 patients with acute myocardial infarction in
acute and subacute stages of the disease. Quantitative data of mitral
regurgitation have been assessed using two quantitative Doppler
techniques--proximal isov... |
27,455 | [Parameters of heart rhythm variability and QT-interval in patients with
ischemic heart disease and type 2 diabetes]. | We studied parameters of heart rhythm variability and QT intervals in 141
patients (mean age 52.4 +/- 7.3 years) with unstable angina and acute myocardial
infarction; 101 of these patients (71.6%) had type 2 diabetes. We found that in
patients with diabetes parameters RRNN, LF and LF/HF were significantly lower.
In... |
27,456 | [Causes of reoperations and their outcomes in patients with the Marfan's
syndrome after correction of the ascending aorta aneurysm and aortic
insufficiency]. | Aim of the study was to elucidate causes of repeat operations and their outcomes
in patients with the Marfan's syndrome. Between December 1972 and January 2009
60 patients with Marfan's syndrome were operated for aneurysm of the ascending
aorta and aortic insufficiency. All patients were subjected to ascending aorta... |
27,457 | [Unfavorable effect of the period of new year holidays on total and
cardiovascular mortality]. | We studied effect of the period of new year holydays on parameters of total and
cardiovascular mortality. We analyzed all registered deaths in Kemerovo from
01.01.1998 to 31.12.2001 using data of the Kemerovo registry office (ZAGS). In
time interval from 21 December to January 10 of each year there were 1830 deaths ... |
27,458 | [Dynamics of prevalence of arterial hypertension and other risk factors of
development of cardiovascular diseases in female population of Tallin (10 year
prospective study)]. | Aim of the study was to assess dynamics of prevalence of arterial hypertension
(AH) and main cardiovascular risk factors (RF) in a women population of Tallin
during 10 years of follow up. In 2008-2009 we repeated measurements of arterial
pressure (AP), electrocardiographic, echocardiographic, and complex laboratory ... |
27,459 | [Comparative clinical and anatomic characteristic of patients with patent
foramen ovale in cryptogenic and noncryptogenic stroke]. | In order to study anatomical and functional characteristics of patent foramen
ovale (PFO) in patients with cryptogenic stroke and with other stroke subtypes
we examined 56 stroke patients (male--35, female--21, age 46.7 +/- 16.5 years)
with PFO and ischemic stroke. Diagnosis of PFO was made by transesophageal
echoc... |
27,460 | [Value of pleiotropic effects of angiotensin-converting enzyme inhibitors]. | Recently the pleiotropic effects of angiotensin-converting enzyme inhibitors
which lay beyond their pure antihypertensive effects are widely discussed.
Antiproliferative, antiatherosclerotic, antiproliferative and antiarrhythmic
properties, as well as positive effects on hemostasis and endothelial function
allows a... |
27,461 | [Antianginal efficacy and tolerability of ivabradine in the therapy of patients
with stable angina: results of the CONTROL study]. | Control of heart rate (HR) is an important target during treatment of patients
with stable angina. In a number of cases it can be achieved by the use of
beta-adrenoblockers. But often a necessity arises to enhance pulse slowing
therapy with the use of combinations of drugs exerting negative chronotropic
effect. We ... |
27,462 | [Detection of erectile dysfunction and peculiarities of its treatment in men
with high cardiovascular risk]. | It has been demonstrated in a series of studies that erectile dysfunction (ED)
appears to be one of risk factors and predictors of ischemic heart disease
(IHD). According to the SSRC PM data in a cohort of 300 men with high
cardiovascular risk ED was diagnosed in 61% of cases, while among 300 men with
verified diag... |
27,463 | [Modern aspects of war against smoking: are there any opportunities left?]. | The war against smoking requires taking immediate measures because of the
growing spread and severe consequences. All minuses and pluses of the Mass Media
are underlined in this article. Anti-smoking technical means should to meet the
following requirements: (1) each inhalation of cigarette smoke should be carried
... |
27,464 | [Antiarrhythmic activity of omega-3 polyunsaturated fatty acids in patients with
stable ischemic heart disease and ventricular rhythm disturbances]. | The purpose of this investigation is to evaluate the influence of purified
highly-concentrated omega-3 polyunsaturated fatty acids (90% omega-3
polyunsaturated fatty acids 1 g/day) on the severe ventricular arrythmias in
patients with stable coronary heart disease (CHD) without concomitant left
ventricular contract... |
27,465 | [Dynamics of biochemical markers of reparative fibrosis in uncomplicated course
of myocardial infarction]. | Dynamics of biochemical markers of reparative fibrosis in patients with
myocardial infarction (MI) with complicated course did not differ from that in
the group of patients without complications. Development of complications was
associated with elevation of blood serum content of glucosaminoglycans in phase
3 of re... |
27,466 | [Efficacy of shock-wave therapy in the treatment of chronic ischemic heart
failure]. | INTRODUCTION: Shock-wave therapy (SWT) has proved its efficacy and safety in a
number of studies in stable effort angina.
METHODS: Twenty-four patients (20 men, 4 women; mean age 63.3 +/- 6.1 years)
with chronic heart failure (CHF) of ischemic origin (>6 months after AMI) and
left ventricular (LV) ejection fraction ... |
27,467 | [Qualitative and quantitative changes of circulating in blood endotheliocyte
precursor cells in patients with hypercholesterolemia]. | Aim of this study was elucidation of diagnostic value of qualitative and
quantitative parameters of circulating endotheliocyte precursor cells (EPC), in
the state of apoptosis (apoptotic endotheliocytes A AE), as well as effect of
main risk factors on the studied parameters in patients with coronary
atherosclerosis... |
27,468 | [Neonatal gastroenteritis triggers long-term cardiomyocyte atrophy, remodeling
and irreversible hyperpolyploidization]. | Growth retardation, inflammation and cardiac overload in early childhood are
linked with hypertension and infarction in adults. This link was termed as
developmental programming. Exact mechanisms and critical time frames for
development of the heart are still unknown. To elucidate these questions, we
developed a mo... |
27,469 | [Acute and postponed action of adriamycin on the contractile function and
antioxidant status of the myocardium]. | Functional, biochemical and morphological studies of rat cardiac muscle after
single injection of adriamycin (2.2 mg/kg) were carried out. The myocardium was
taken for studies in 2 hours and in 2-3 weeks after adriamycin injection. The
isolated heart was perfused retrogradely with Krebs solution and left
ventricula... |
27,470 | [Independent predictors of deep vein thrombosis (results of prospective 18
months study)]. | We followed for 18 months 90 patients who had had deep vein thrombosis (DVE)
and/or pulmonary embolism (PE) and received therapy with anticoagulants either
for 3-12 months or for indefinitely long time. During follow-up rate of
recurrent DVE was 16.7%, no recurrences of PE were registered. Predictors of
recurrent P... |
27,471 | [Interrelationship between antibodies to enzymes of antioxidant system and
cardiac involvement in patients with systemic scleroderma]. | In blood of patients with systemic scleroderma we detected antibodies to the
antioxidant system enzymes. Level of specific immunoglobulins rose with increase
of the disease activity. Antioxidant system of the body is represented by a
number of enzymes called to negate pathogenic effect of active forms of oxygen.
In... |
27,472 | [Evolution of oral drug forms of metoprolol: advantages of long acting modified
release forms with modified release]. | Review oral modified release drug forms of beta-adrenoblocker metoprolol which
is used in arterial hypertension and ischemic heart disease is presented.
Metoprolol has salts such as tartrate which is used for production of immediate
release (IR) and sustained release (SR) forms and succinate used for production
of ... |
27,473 | [Myocardial hypertrophy in patients with hypertensive disease: the role of
genetic polymorphism of beta-adrenoreactive structures]. | Aim of the study was investigation of association of polymorphic markers
Gly389Arg and Ser49Gly of ADRB1 gene, Gly1l6Arg and Glu27Gln of ADRB2 gene,
Trp64Arg of ADRB3 gene, and 825 of GNB3 gene with structural and functional
peculiarities of the left ventricular (LV) myocardium in patients with
hypertensive disease... |
27,474 | [Evaluation of long-term therapy influence with angiotensin converting enzyme
inhibitor lisinopril on morphofunctional parameters of the left ventricle,
peripheral artery endothelium disfunction and painless myocardial ischemia in
premenopausal women with hypertension]. | Aim of the study was to assess influence of long-term therapy with angiotensin
converting enzyme inhibitor lisinopril on morphofunctional parameters of the
left ventricle (LV) and painless myocardial ischemia in 109 premenopausal women
with stage II hypertension depending on functional state of peripheral artery
en... |
27,475 | [Comparison of transthoracic, transesophageal, and intracardiac echocardiography
sensitivity for guiding transseptal puncture during radiofrequency ablation in
the left atrium]. | The paper contains comparison of sensitivity and rates of false negative results
of transthoracic (TT), transesophageal (TE), and intracardiac (IC)
echocardiography (echoCG) during transseptal puncture in the run of the
procedure of radiofrequency ablation of atrial fibrillation. In the work
fulfilled we analyzed r... |
27,476 | [Stromal progenitor cells and blood leukocytes after implantation of
drug-eluting stents]. | Aim of the study was to assess participation in development of restenosis of
circulating in blood progenitor cells of stromal line of differentiation and
polymorphonuclear granulocytes. We compared levels of osteonectin positive
progenitor cells, neutrophils, eosinophils, and basophils in blood of patients
with isc... |
27,477 | [Disturbances of homocysteine metabolism as a risk factor of cardiovascular
diseases development: effect on prognosis and possibilities of correction with
drugs]. | Classical risk factors of development of cardiovascular diseases does not allow
to detect all persons needing active prevention. Because of this reason great
attention is given to novel biomarkers one of which is homocysteine. Most
widely-spread causes of elevation of homocysteine level are such factors as
deficit ... |
27,478 | [Acute coronary syndrome with ST segment depression on ECG: novel outlook of an
old problem]. | The lecture is devoted to morphological manifestations, clinical and prognostic
features of acute coronary syndrome (ACS) with ST segment depressions on ECG. We
have studied peculiarities of clinical course of this variant of ACS and its
outcomes in 501 patients and suggested a scheme for stratification of patients ... |
27,479 | [Contemporary approaches to echocardiographic assessment of left heart ventricle
diastolic function]. | Recommendations on echocardiographic diagnosis of diastolic function of the left
ventricle of the heart are analyzed in this paper. Possibilities of
echocardiography for early detection of disturbances of left ventricular
relaxation and of pronounced derangements of diastolic function are shown.
Difficulties of dia... |
27,480 | [Spousal concordance for factors related to metabolic syndrome in families of
patients with premature coronary heart disease]. | PURPOSE: To elucidate risk factors concordance between spouses in families of
patients with "premature" coronary heart disease (CHD).
METHODS: We examined 174 spouse pairs. There were 174 probands with "premature"
(onset before 55 years) CHD aged 32-63 years and 174 their spouses aged 28-63
years. Among probands 18.... |
27,481 | [Analysis of polymorphism of three positions of promoter region of TNF- gene in
patients with ischemic heart disease, unstable angina and myocardial
infarction]. | We studied polymorphism of three positions of promoter region of TNF alpha gene
in patients with ischemic heart disease (IHD), development of unstable angina
(UA) and acute myocardial infarction (MI). Analysis of frequencies of genotypes
in position A308 showed that heterozygotness in patients with cardiovascular
d... |
27,482 | [Peculiarities of dynamics and prognostic value of NT-proBNP level in different
variants of treatment of patients with acute coronary syndrome]. | Aim of the study was to assess dynamics of NT proBNP in ACS as well as to
analyze effect of different methods of treatment on the level of the parameter
and its prognostic value.
MATERIAL AND METHODS: Patients aged 30-70 years were included into the study: 52
patients with ST segment elevation ACS (STEACS), 61 patie... |
27,483 | [Non-ST-elevation acute coronary syndrome. Comparison of effects of atorvastatin
and rosuvastatin on blood levels of lipids and markers of inflammation]. | Data on rapid effects of statins in patients (pts) with acute coronary syndrome
(ACS) are mostly from trials of atorvastatin (ATO). We hypothesized that due to
high potency 10 mg of rosuvastatin (ROS) would produce same changes of lipids
and inflammation markers as 40 mg ATO.
METHODS: We openly randomized 53 pts (69... |
27,484 | [Prognostic value of cardiovascular autonomic neuropathy in patients with
combination type 2 diabetes mellitus and chronic heart failure]. | Type 2 diabetes mellitus (DM) is often combined with chronic heart failure
(CHF). Cardiovascular autonomic neuropathy (CAN) is widely spread complication
of DM. In this work we studied effect of CAN on the course of CHF in patients
with type 2 DM. We have shown unfavorable effect of CAN on the rate of
development o... |
27,485 | [Application of methods of renal replacement therapy for abolishment of
hyperhydration in patients with decompensated chronic heart failure]. | Slow continuous ultrafiltration (SCUF), continuous veno venous haemofiltration
(CVVHF) are alternative to diuretics methods of treatment of patients with
chronic heart failure (CHF), edematous syndrome.
METHODS: Patients of both sexes aged 30-82 years with functional class II-IV CHF
were included because of decompen... |
27,486 | [Characteristics of central pulse wave in young men with various phenotypes of
arterial pressure]. | In this work we compared parameters of central arterial pressure (AP) on the
basis of analysis of pulse wave in young men in dependence of AP phenotype
determined by repetitive clinical measurements and 24 hour AP monitoring
(24HAPM). Comparison of characteristics of central pulse wave was carried out in
12 men wit... |
27,487 | [ATR1 gene polymorphism in patients with hypertrophic cardiomyopathy and
hypertensive heart]. | Aim of the study was analysis of dependence of clinical picture and degree of
severity of left ventricular hypertrophy (LVH) on polymorphism A/C of ATR1 gene
in patients with hypertrophic cardiomyopathy (HCMP) and hypertensive disease
(HD). With the method of polymerase chain reaction genotyping for polymorphic
mar... |
27,488 | [Relationship between activity of fibrinolysis, parameters of lipid spectrum and
carbohydrate metabolism]. | In this work analysis of results of a prospective populational cohort study
"Stress and health in Russia" is presented. We included in the study inhabitants
of Moscow randomly sampled from the population of men and women aged > or =55
years. Aim of the present work consisted in the study of relationship of
activity... |
27,489 | [Mechanism of stimulation of angiogenesis in ischemic myocardium with the help
of adipose tissue stromal cells]. | Stromal cells from subcutaneous adipose tissue (adipose derived stromal cells -
ASCs) are perspective for cell therapy of ischemic states because of ability to
stimulate growth of vessels. For the elucidation of mechanisms of angiogenic
action of ASCs we used the model of co-cultivation of ASCs with cells isolated
... |
27,490 | [Optimal method of revascularization in patients with multivessel coronary
artery involvement for application of drug eluting stents: percutaneous coronary
interventions in comparison with coronary bypassing]. | Drug eluting stents (DES) which appeared in the beginning of 21-st century
allowed to elevated percutaneous coronary interventions (PCI) to a novel level.
High efficacy of DES has been proven in a row of conducted clinical studies:
after their implantation low percentage of in stent restenosis and low rate of
repet... |
27,491 | [In-hospital and long-term (to 3 years) results of using bare-metal stents in
patients with coronary artery disease and chronic kidney disease]. | Patients (n=727) who had been subjected to implantation of one or several
standard stents in 2004 were included into this study. These patients were
divided into 3 groups according to initial level of glomerular filtration rate
(GFR, MDRD equation): group 1 - 466 patients with GFR >60 ml/min/1,73 m(2),
group 2 - 23... |
27,492 | [Effect of beta-adrenoblockers on remodeling of myocardium and adhesive function
of endothelium in patients with ischemic heart disease, complicated with chronic
heart failure and atrial fibrillation]. | AIM: To elucidate effect of adrenoblockers on remodeling of myocardium and
adhesive function of endothelium in with ischemic heart disease with chronic
heart failure (CHF) and addition of atrial fibrillation (AF).
MATERIAL AND METHODS: We included into the study 77 patients with functional
class II-III CHF and AF of... |
27,493 | [Right ventricular remodeling after myocardial infarctions of different
location]. | AIM: To study dynamic dimensional and functional changes of both ventricles
after myocardial infarctions (MI) of different locations.
MATERIAL AND METHODS: Patients with first acute ST elevation MI (n=180) were
distribution to 3 groups: anterior (AMI), inferior (IMI), and posterolateral
(PLMI). EchoCG dimensional pa... |
27,494 | [Own and parental predictors of arterial prehypertension and hypertension in
children of persons with premature coronary heart disease]. | AIM: to elucidate own and parental predictors of arterial prehypertension
(PreHT) and hypertension (HT) in children of patients with premature manifested
before 55 years in men or before 60 years in women) coronary heart disease
(CHD).
METHODS: We surveyed 276 families: 258 probands parents with premature CHD,
thei... |
27,495 | [Comparison of dysrhythmias in women with hypertension in the period of
premenopause and in late fertile period with altered hormonal background in
dependence on the variant of left ventricular modeling]. | We carried out 24 hour Holter ECG monitoring in 106 women with hypertension in
the period of premenopause and in late fertile period with altered hormonal
background. Comparative analysis of character and structure of dysrhythmias
showed that supraventricular premature beats including rapid and allorhythmic
extrasy... |
27,496 | [Pulmonary involvement in patients with hypertensive disease]. | METHODS: Parameters of spirometry, body plethysmography, and pulmonary diffusion
capacity were measured in 46 patients (age 35-60 years, 40 men, 6 women) with
stage I-II hypertensive disease (HD) without bronchial and pulmonary diseases,
systolic dysfunction of left ventricular myocardium, obesity, current or past
... |
27,497 | [Possibilities of atorvastatin in complex management of extensive psoriasis in
patients with arterial hypertension]. | Efficacy and safety of the use of atorvastatin in complex treatment of extensive
psoriasis was studied in 63 patients with psoriasis and arterial hypertension
(AH). Complex clinical functional examination was carried out at study entry and
after 6 months of treatment. Psoriasis severity was evaluated with PASI scale... |
27,498 | [Functional state of arterioles in patients with essential hypertension and
arterial hypertension developed at the background of diabetes mellitus]. | With the aim of studying linear velocity characteristics of arteriolar blood
flow and reactivity of arterioles we examined 80 patients with essential
arterial hypertension (AH), 83 patients with type 2 diabetes mellitus (DM) with
concomitant AH, and 63 healthy people. In all patients examination included
ultrasound... |
27,499 | [Clinical-morphological changes of venous system of the heart in dependence on
the stage of chronic heart failure]. | Cardiac venous system (CVS) in chronic heart failure (CHF) undergoes whole row
of morpho functional changes, but investigations of CVS are practically absent.
We studied CVS of patients with Doppler echocardiography and magnetic computer
tomography of the heart. The state of peripheral venous system was assessed by ... |
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