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5,800
Unusual features of apical hypertrophic cardiomyopathy.
Apical hypertrophic cardiomyopathy (HC) is commonly regarded as a relatively benign condition of young to middle-aged Japanese men. Apical HC in a predominantly Caucasian population is not well characterized. The cardiovascular characteristics, morbidity, and mortality of a series of elderly, predominantly Caucasian su...
5,801
Relationships between emerging measures of heart failure processes of care and clinical outcomes.
Previous studies have not confirmed associations between some current performance measures for inpatient heart failure processes of care and postdischarge outcomes. It is unknown if alternative measures are associated with outcomes.</AbstractText>Using data for 20,441 Medicare beneficiaries in OPTIMIZE-HF from March 20...
5,802
The prognostic impact of shocks for clinical and induced arrhythmias on morbidity and mortality among patients with implantable cardioverter-defibrillators.
Recent investigations have demonstrated that the occurrence of implantable cardioverter-defibrillator (ICD) shocks is associated with adverse long-term outcomes. These studies have emphasized that the risk is most reasonably due to arrhythmias rather than to the shock itself. We sought to compare the impact of shock de...
5,803
Periodic acceleration (pGz) prior to whole body ischemia reperfusion injury provides early cardioprotective preconditioning.
Periodic acceleration (pGz) is a method that applies repetitive sinusoidal head-to-foot motion to the horizontally positioned body. pGz adds pulses to the circulation as a function of frequency, thereby increasing shear stress to the endothelium. Pulsatile shear stress increases release of cardioprotective endothelial-...
5,804
Intra-arrest selective brain cooling improves success of resuscitation in a porcine model of prolonged cardiac arrest.
We have previously demonstrated that early intra-nasal cooling improved post-resuscitation neurological outcomes. The present study utilizing a porcine model of prolonged cardiac arrest investigated the effects of intra-nasal cooling initiated at the start of cardiopulmonary resuscitation (CPR) on resuscitation success...
5,805
The relationship between time to arrival of emergency medical services (EMS) and survival from out-of-hospital ventricular fibrillation cardiac arrest.
We examined the relationship between time from collapse to arrival of emergency medical services (EMS) and survival to hospital discharge for out-of-hospital ventricular fibrillation cardiac arrests in order to determine meaningful interpretations of this association.</AbstractText>We calculated survival rates in 1-min...
5,806
Vagal tone augmentation to the atrioventricular node in humans: efficacy and safety of burst endocardial stimulation.
Control of atrioventricular (AV) nodal conduction by endocardial stimulation of efferent AV nodal vagal fibers [atrioventricular nodal vagal stimulation (AVNS)] is a promising approach for long-term device-based modulation of ventricular rate during atrial fibrillation (AF). However, few data on the efficacy of AVNS de...
5,807
High prevalence of early repolarization in short QT syndrome.
Short QT syndrome (SQTS) is characterized by an abnormally short QT interval and sudden death. Due to the limited number of cases, the characteristics of SQTS are not well understood. It has been reported recently that early repolarization is associated with idiopathic ventricular fibrillation and the QT interval is sh...
5,808
Pilsicainide.
Pilsicainide is a class Ic antiarrhythmic agent used for the treatment of supraventricular and ventricular tachycardia. The pharmacodynamic effects of pilsicainide are achieved via selective sodium channel blockade. In randomized, multicentre trials in patients with atrial fibrillation, restoration of sinus rhythm was ...
5,809
Use of the wearable external cardiac defibrillator in children.
The wearable cardiac defibrillator (WCD) is an alternative to the implantation of cardioverter defibrillator (ICD) for patients at risk for sudden death who do not fulfill standard criteria for ICD implantation or in whom the risk:benefit ratio is equivocal. Published data pertaining to the WCD in children is sparse. W...
5,810
Atrial-selective sodium channel block as a novel strategy for the management of atrial fibrillation.
Safe and effective pharmacologic management of atrial fibrillation (AF) is one of the greatest challenges facing an aging society. Currently available pharmacologic strategies for rhythm control of AF are associated with ventricular arrhythmias and in some cases multi-organ toxicity. Consequently, drug development has ...
5,811
Chaotic atrial tachycardia-related ventricular fibrillation in a 2-month-old baby with Wolff-Parkinson-White syndrome.
A 2-month-old baby was resuscitated from ventricular fibrillation attributed to a concurrent chaotic atrial tachycardia with Wolff-Parkinson-White syndrome. He underwent successful radiofrequency catheter ablation of an accessory pathway. Throughout the 4-year follow-up after the procedure, the boy remained free of any...
5,812
Same morphology of ventricular premature complexes triggering repeated ventricular fibrillation.
Episodes ventricular fibrillation (VF) initiated by ventricular premature complexes (VPCs) of a single morphology have been reported. However, the characteristics of the VPCs over long periods of time are unknown.</AbstractText>To compare the morphologies and coupling intervals of VPCs that initiate episodes of VF that...
5,813
A prospective 1-year study of changes in neuropsychological functioning after implantable cardioverter-defibrillator surgery.
The testing of the implantable cardioverter-defibrillator (ICD), through the induction of repeated episodes of ventricular fibrillation, has been associated with disturbances in cerebral activity and increased levels of cytoplasmic enzymes. However, the neuropsychological outcomes of cerebral changes and their quality-...
5,814
Type 2 diabetes mellitus and the risk of sudden cardiac arrest in the community.
The reduction of mortality from sudden cardiac arrest (SCA) in the setting of coronary heart disease (CHD) remains a major challenge, especially among patients with type 2 diabetes. Diabetes is associated with an increased risk of SCA, at least in part, from an increased presence and extent of coronary atherosclerosis ...
5,815
Abnormal action potential duration restitution property in the right ventricular outflow tract in Brugada syndrome.
Although patients with Brugada syndrome (BS) are at risk of ventricular fibrillation (VF) and ensuing death, the action potential duration (APD) restitution properties of the right ventricular outflow tract (RVOT) in patients with BS remain undetermined.</AbstractText>Endocardial monophasic action potentials (MAPs) wer...
5,816
Strategies to reduce the risk of transvenous lead extraction: an example using a hybrid approach in a patient with a haemodialysis fistula.
Haemodialysis (HD) patients are at increased risk of vascular access complications with device therapy. We report a case of transvenous defibrillator lead extraction from the ipsilateral side as an HD fistula. The procedure was successfully performed using a hybrid approach, with extraction of the lead with a powered s...
5,817
Loss of biventricular pacing due to T-wave oversensing.
The benefits obtained with cardiac resynchronization therapy are directly related to the occurrence of continuous biventricular pacing. We report a case of intermittent loss of biventricular pacing due to ventricular oversensing that worsened the functional status of the patient.
5,818
Usefulness of statins in preventing atrial fibrillation in patients with permanent pacemaker: a systematic review.
Patients with permanent pacemakers (PM) are at high risk of developing atrial fibrillation (AF). Minimal ventricular pacing modalities have been demonstrated to reduce AF in such patients, although they are not suitable for patients with advanced atrioventricular conduction disease. Recent evidences suggest that 3-hydr...
5,819
Ischaemia-modified albumin predicts the outcome of cardiopulmonary resuscitation: An experimental study.
Ischaemia-modified albumin (IMA) has recently been shown to be an early and sensitive marker of ischaemia. It is generally accepted that cardiac arrest causes the most severe form of global ischaemia. The aim of the present study was to identify whether IMA is an independent predictor of return of spontaneous circulati...
5,820
Circadian variation of late potentials in idiopathic ventricular fibrillation associated with J waves: insights into alternative pathophysiology and risk stratification.
The presence of J waves on ECGs is related to idiopathic ventricular fibrillation (VF).</AbstractText>The purpose of this study was to investigate the pathophysiology of J waves by assessing risk markers that reflect electrophysiologic abnormalities.</AbstractText>The study enrolled 22 idiopathic VF patients (17 men an...
5,821
Electrophysiological characteristics of the Marshall bundle in humans.
Marshall bundles (MBs) are the muscle bundles within the ligament of Marshall.</AbstractText>This trial sought to the electrophysiological characteristics of the MB and the anatomical connections between MB and left atrium (LA) in patients with persistent atrial fibrillation (AF).</AbstractText>We enrolled 72 patients ...
5,822
Epicardial Catheter Ablation of Atrial Fibrillation.
Atrial fibrillation (AF) can cause significant symptoms despite control of ventricular rate, and for some patients a rhythm-control strategy is more appropriate. Because antiarrhythmic drugs have limited efficacy for treating AF and can cause significant side effects, nonpharmacologic therapy has found a growing role i...
5,823
Medtentia double helix mitral annuloplasty system evaluated in a porcine experimental model.
: To further develop and improve minimally invasive surgical procedures, dedicated appropriate surgical devices are mandatory. In this study, the safety and feasibility of implanting the novel Medtentia double helix mitral annuloplasty ring, which uses the key-ring principle to potentially allow faster and sutureless i...
5,824
Dilated cardiomyopathy and role of antithrombotic therapy.
There is no consensus as to whether anticoagulation has a favorable risk:benefit in reducing thromboembolic events in patients with heart failure (HF) secondary to dilated cardiomyopathy who do not suffer from atrial fibrillation or primary valvular disease.</AbstractText>The literature reviewed on this topic included ...
5,825
Noncompaction of ventricular myocardium associated with hypertrophic cardiomyopathy and polycystic kidney disease.
Noncompaction of ventricular myocardium (NVM), a relatively new diagnostic entity, is described as an arrest in the process of compaction of myocardial fibers, which results in a prominent trabecular network and deep intertrabecular recesses. Its coexistence with other cardiac anomalies like hypertrophic obstructive ca...
5,826
Ventricular fibrillation during anesthesia in a Wenchuan earthquake victim with crush syndrome.
We cared for a victim of the Wenchuan earthquake who was rescued after being buried in rubble for 52 hours. On admission to the hospital, the patient had severe hyperkalemic acidosis and necrosis of both legs, requiring bilateral amputation. In the operating room, the patient developed ventricular fibrillation. The pat...
5,827
Cyanide poisoning and cardiac disorders: 161 cases.
Inhalation of hydrogen cyanide from smoke in structural fires is common, but cardiovascular function in these patients is poorly documented.</AbstractText>The objective was to study the cardiac complications of cyanide poisoning in patients who received early administration of a cyanide antidote, hydroxocobalamin (Cyan...
5,828
Differences in effects of electrical therapy type for ventricular arrhythmias on mortality in implantable cardioverter-defibrillator patients.
Implantable cardioverter-defibrillator (ICD) shocks have been associated with an increased risk of death. It is unknown whether this is due to the ventricular arrhythmia (VA) or shocks and whether antitachycardia pacing (ATP) termination can reduce this risk.</AbstractText>The purpose of this study was to determine whe...
5,829
Loss of pace capture on the ablation line: a new marker for complete radiofrequency lesions to achieve pulmonary vein isolation.
Catheter ablation procedures for atrial fibrillation (AF) often involve circumferential antral isolation of pulmonary veins (PV). Inability to reliably identify conduction gaps on the ablation line necessitates placing additional lesions within the intended lesion set.</AbstractText>This pilot study investigated the re...
5,830
Prognostic importance of atrial fibrillation in implantable cardioverter-defibrillator patients.
This study aimed to assess the prevalence of different types of atrial fibrillation (AF) and their prognostic importance in implantable cardioverter-defibrillator (ICD) patients.</AbstractText>The prevalence of AF has taken epidemic proportions in the population with cardiovascular disease. The prognostic importance of...
5,831
High-frequency ventricular ectopy can increase sympathetic neural activity in humans.
Sudden cardiac death is usually caused by ventricular arrhythmias and in many cases, is preceded by frequent ventricular ectopy. It is known that ectopic beats cause transient increases in sympathetic nerve activity (SNA).</AbstractText>Because high SNA is known to be arrhythmogenic, we hypothesized that high rates of ...
5,832
Causes of ventricular oversensing in implantable cardioverter-defibrillators: implications for diagnosis of lead fracture.
Implantable cardioverter-defibrillator (ICD) ventricular oversensing may result in inappropriate therapy, which may be triggered by lead/connection issues that require surgical revision or physiologic oversensing that may be resolved with reprogramming. The sensing integrity counter (SIC) is an oversensing diagnostic t...
5,833
Deglutition syncope associated with ventricular asystole in a patient with permanent atrial fibrillation.
Deglutition syncope is a situational syncope that is diagnosed only by a detailed history. We report deglutition syncope in a 62-year-old man, who had permanent atrial fibrillation. The patient had no structural or functional abnormalities of the esophagus. During syncopal attacks, his electrocardiography showed ventri...
5,834
A hypokalemic muscular weakness after licorice ingestion: a case report.
A 21-year-old male presented to the emergency department with the complaint of muscle weakness. The patient had used a powderized over-the-counter product named 'Tekumut' for 2 weeks to quit smoking. The granulated product was studied and determined to contain 'licorice' containing glycyrrhizic acid.Licorice (a plant w...
5,835
Eosinophilic myocarditis mimicking acute coronary syndrome secondary to idiopathic hypereosinophilic syndrome: a case report.
Eosinophilic myocarditis is a rare form of myocarditis. It is characterized pathologically by diffuse or focal myocardial inflammation with eosinophilic infiltration, often in association with peripheral blood eosinophilia. We report a case of eosinophilic myocarditis secondary to hypereosinophilic syndrome.</AbstractT...
5,836
Canine atrial fibrillation.
Atrial fibrillation (AF) is the most commonly diagnosed supraventricular tachyarrhythmia in dogs. It typically develops when atrial enlargement occurs secondary to underlying cardiovascular disease. Electrocardiographically, AF is characterized by disorganized atrial electrical activity resulting in an absence of P wav...
5,837
New developments in atrial antiarrhythmic drug therapy.
Atrial fibrillation (AF) is a growing clinical problem associated with increased morbidity and mortality. Currently available antiarrhythmic drugs (AADs), although highly effective in acute cardioversion of paroxysmal AF, are generally only moderately successful in long-term maintenance of sinus rhythm. The use of AADs...
5,838
Influence of co-existing atrial fibrillation on the efficacy of atorvastatin treatment in patients with dilated cardiomyopathy: a pilot study.
The aim of the study was to assess the influence of co-existing atrial fibrillation (AF) on inflammatory condition factors, left ventricular function, clinical course and the efficacy of statin treatment of congestive heart failure in the course of dilated cardiomyopathy (DCM).</AbstractText>In a prospective, randomize...
5,839
A randomized comparison of cardiocerebral and cardiopulmonary resuscitation using a swine model of prolonged ventricular fibrillation.
Cardiocerebral resuscitation (CCR) is reportedly superior to cardiopulmonary resuscitation (CPR) for primary cardiac arrest in the prehospital setting. This study was done using a swine model of prolonged ventricular fibrillation (VF) to quantify the effect of the emergency medical services component of CCR with intrao...
5,840
Protective effects of estrogen against reperfusion arrhythmias following severe myocardial ischemia in rats.
Female sex hormones may have protective effects against arrhythmias, including reperfusion arrhythmias (RAs), but the mechanisms are still not completely known.</AbstractText>Serial changes in rat hearts (rhythm, apoptosis and the its infuencing factors; cardiac vinculin mRNA expression and connexin43 (Cx43) dephosphor...
5,841
Pediatric out-of-hospital cardiac arrest in Korea: A nationwide population-based study.
Our objective was to describe the incidence and demographics of pediatric out-of-hospital cardiac arrest (OHCA) in Korea.</AbstractText>We identified non-traumatic OHCA patients aged less than 20 years from a Korean nationwide OHCA registry (2006-2007). Data from emergency medical service (EMS) run-sheets and hospital ...
5,842
The E-wave delayed relaxation pattern to LV pressure contour relation: model-based prediction with in vivo validation.
The transmitral Doppler E-wave "delayed relaxation" (DR) pattern is an established sign of diastolic dysfunction (DD). Furthermore, chambers exhibiting a DR filling pattern are also expected to have a prolonged time-constant of isovolumic relaxation (tau). The simultaneous observation of a DR pattern and normal tau in ...
5,843
Left main coronary artery occlusion after percutaneous aortic valve implantation.
Left main coronary artery occlusion occurred immediately after transfemoral aortic valve implantation in an 87-year-old woman, which resulted in ventricular fibrillation and hemodynamic collapse. This life-threatening complication was promptly diagnosed with transesophageal echocardiography, which showed the disappeara...
5,844
[Effects of hypertension state induced by norepinephrine on liver in a swine model of cardiopulmonary resuscitation].
To study the effects of norepinephrine (NE)-induced hypertension (HT) on hepatic function and pathology after restoration of spontaneous circulation (ROSC) by cardiopulmonary resuscitation (CPR) in swine.</AbstractText>After 4 minutes of induced ventricular fibrillation (VF), standard CPR was carried out, and then the ...
5,845
[The influence of hypothermia therapy on enzymology and pathology of lung after cardiac arrest].
To study the effect of hypothermia on pro-inflammatory mediators in serum, the enzymology and pathology of lung tissue.</AbstractText>Ventricular fibrillation for 4 minutes was induced in 10 domestic pigs. Standard cardiopulmonary resuscitation was given to them. They were then divided into two groups according to the ...
5,846
Influence of coffee and caffeine consumption on atrial fibrillation in hypertensive patients.
Coffee and caffeine are widely consumed in Western countries. Little information is available on the influence of coffee and caffeine consumption on atrial fibrillation (AF) in hypertensive patients. We sought to investigate the relationship between coffee consumption and atrial fibrillation with regard to spontaneous ...
5,847
On the reliability of frequency components in systolic arterial pressure in patients with atrial fibrillation.
Atrial fibrillation (AF) is characterized by desynchronization of atrial electrical activity causing a consequent irregular ventricular response. In AF, the beat-to-beat variation of blood pressure is increased because of variations in filling time and contractility. However, only a few studies have analyzed short-term...
5,848
Late sinus and atrial tachycardia after pediatric heart transplantation might predict poor outcome.
Our objective was to examine clinical/electrocardiogram (ECG) predictors and outcomes of arrhythmias beyond 1 year after pediatric heart transplantation (HTx). We performed a retrospective chart review of 94 1-year HTx survivors, 1988-2006. Clinical records identified patients with arrhythmias occurring &gt;1 year afte...
5,849
Changes in interleukin-10 mRNA expression are predictive for 9-day survival of pigs in an emergency preservation and resuscitation model.
This study aimed at evaluating (I) the impact of different intra-arrest hypothermia levels on the expression of selected cytokines and (II) their prognostic value for 9-day survival.</AbstractText>Female Large White pigs (n=21, 31-38 kg) were subjected to 15 min of ventricular fibrillation, followed by intra-arrest car...
5,850
Fatty acid percentage in erythrocyte membranes of atrial flutter/fibrillation patients and controls.
Several epidemiological published data support the protective role of omega-3 consumption in coronary artery disease, sudden cardiac death and ventricular arrhythmias, but interestingly, this is not the case for atrial arrhythmias. The purpose of this study is to evaluate different fatty acid profile between AF/AFL sub...
5,851
Determinants of delayed preconditioning against myocardial stunning in chronically-instrumented pigs.
To test the hypothesis that a critical stenosis prevents delayed preconditioning against stunning, studies were conducted in pigs chronically-instrumented with occluders and segment-shortening crystals. In the setting of a critical stenosis, a preconditioning stimulus of repetitive brief occlusions resulted in infarcti...
5,852
Outcomes from low versus high-flow cardiopulmonary resuscitation in a swine model of cardiac arrest.
Return of spontaneous circulation (ROSC) is improved by greater vital organ blood flow during cardiopulmonary resuscitation (CPR). We tested the hypothesis that myocardial flow above the threshold needed for ROSC may be associated with greater vital organ injury and worse outcome.</AbstractText>Aortic and right atrial ...
5,853
Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation.
Hypothermia improves survival and neurological recovery after cardiac arrest. Pro-inflammatory cytokines have been implicated in focal cerebral ischemia/reperfusion injury. It is unknown whether cardiac arrest also triggers the release of cerebral inflammatory molecules, and whether therapeutic hypothermia alters this ...
5,854
Epilepsy or syncope? An analysis of 55 consecutive patients with loss of consciousness, convulsions, falls, and no EEG abnormalities.
Patients with loss of consciousness and convulsion often have the diagnosis of epilepsy despite normal electroencephalograms (EEGs).</AbstractText>To evaluate the proportion of patients referred to neurologists with presumed epilepsy and normal EEGs who have an alternative cause of syncope.</AbstractText>It was a cross...
5,855
Ablation of severe drug-resistant tachyarrhythmia during pregnancy.
The goal of this study was to describe mapping and ablation of severe arrhythmias during pregnancy, with minimum or no X-ray exposure. Treatment of tachyarrhythmia in pregnancy is a clinical problem. Pharmacotherapy entails a risk of adverse effects and is unsuccessful in some patients. Radiofrequency ablation has been...
5,856
Extracorporeal membrane oxygenation as a rescue of intractable ventricular fibrillation and bridge to heart transplantation.
Extracorporeal membrane oxygenation (ECMO) systems have undergone rapid technological improvements and are now feasible options for medium-term support of severe cardiac or pulmonary failure. Intractable ventricular arrhythmia is a rare but well-established indication for heart transplantation. We report a case of pers...
5,857
Plasma levels of von Willebrand factor are increased in patients with hypertrophic cardiomyopathy.
Hypertrophic cardiomyopathy (HCM) is characterised by inappropriate hypertrophy, small-vessel coronary artery disease, myocyte disarray and increased interstitial fibrosis. Microvascular dysfunction is a common finding in HCM and its extent has been proposed as an important prognostic marker. Plasma von Willebrand fact...
5,858
Ion channel trafficking: a new therapeutic horizon for atrial fibrillation.
Atrial fibrillation (AF) is a common cardiac arrhythmia with potentially life-threatening complications. Drug therapies for treatment of AF that seek long-term maintenance of normal sinus rhythm remain elusive due in large part to proarrhythmic ventricular actions. Kv1.5, which underlies the atrial specific I(Kur) curr...
5,859
Atrioventricular nodal ablation predicts survival benefit in patients with atrial fibrillation receiving cardiac resynchronization therapy.
Cardiac resynchronization therapy (CRT) benefits patients with advanced heart failure. The role of atrioventricular nodal (AVN) ablation in improving CRT outcomes, including survival benefit in CRT recipients with atrial fibrillation, is uncertain.</AbstractText>The purpose of this study was to assess the impact of AVN...
5,860
Microvolt T-wave alternans and electrophysiologic testing predict distinct arrhythmia substrates: implications for identifying patients at risk for sudden cardiac death.
Better risk stratification of patients receiving an implantable cardioverter-defibrillator (ICD) for primary prevention of sudden cardiac death (SCD) is needed. Although microvolt T-wave alternans (MTWA) and electrophysiologic study (EPS) are independent markers for SCD, the Alternans Before Cardioverter Defibrillator ...
5,861
Assessment of ECG interval and restitution parameters in the canine model of short QT syndrome.
The short QT syndrome (SQTS) is characterized by a short QT interval resulting from accelerated ventricular repolarization, and may be associated with ventricular fibrillation but not torsades de pointes. There are abundant data on the adverse effects of long QT, but knowledge of SQTS is sparse. The aim of this study w...
5,862
Infliximab attenuates early myocardial dysfunction after resuscitation in a swine cardiac arrest model.
Left ventricular dysfunction after successful cardiopulmonary resuscitation contributes to early death after resuscitation. Proinflammatory cytokines are known to decrease myocardial function, and tumor necrosis factor-alpha has been shown to increase after successful resuscitation. We hypothesized that blocking the ef...
5,863
Obstructive sleep apnea is common and independently associated with atrial fibrillation in patients with hypertrophic cardiomyopathy.
Hypertrophic cardiomyopathy (HCM) is associated with arrhythmias and cardiovascular death. Left atrial enlargement and atrial fibrillation (AF) are considered markers for death due to heart failure in patients with HCM. Obstructive sleep apnea (OSA) is independently associated with heart remodeling and arrhythmias in o...
5,864
[Prognostic factors of mortality in a cohort of patients with in-hospital cardiorespiratory arrest].
To define the prognostic factors related with mortality of patients who suffer cardiorespiratory arrest (CRA) in the hospital, according to Utstein style guidelines.</AbstractText>A descriptive and prospective study covering a 30-month consecutive period of all the patients who suffered at least one episode of in-hospi...
5,865
J wave syndromes.
The J wave, also referred to as an Osborn wave, is a deflection immediately following the QRS complex of the surface ECG. When partially buried in the R wave, the J wave appears as J-point elevation or ST-segment elevation. Several lines of evidence have suggested that arrhythmias associated with an early repolarizatio...
5,866
Biventricular pacing improves cardiac function and prevents further left atrial remodeling in patients with symptomatic atrial fibrillation after atrioventricular node ablation.
Randomized trials have demonstrated benefits of biventricular (BiV) pacing in patients with advanced heart failure, intraventricular conduction delay, and atrial fibrillation (AF) post-atrioventricular (AV) node ablation. The AV Node Ablation with CLS and CRT Pacing Therapies for Treatment of AF trial (AVAIL CLS/CRT) w...
5,867
Influence of dedicated heart failure clinics on delivery of recommended therapies in outpatient cardiology practices: findings from the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF).
National guidelines recommend heart failure (HF) disease management programs to facilitate adherence to evidence-based practices. This study examined the influence of dedicated HF clinics on delivery of guideline-recommended therapies for cardiology practice outpatients with HF and reduced left ventricular ejection fra...
5,868
Extracorporeal membrane oxygenation as a resuscitation measure in the emergency department.
A 53-year-old man presented to the ED with refractory ventricular fibrillation secondary to an occluded proximal left anterior descending coronary artery. We report the first case of extracorporeal membrane oxygenation instituted in our ED. It is one of the few reports in the literature of extracorporeal membrane oxyge...
5,869
Benefits of thyrotropin suppression versus the risks of adverse effects in differentiated thyroid cancer.
Despite clinical practice guidelines for the management of differentiated thyroid cancer (DTC), there are no recommendations on the optimal serum thyrotropin (TSH) concentration to reduce tumor recurrences and improve survival, while ensuring an optimal quality of life with minimal adverse effects. The aim of this revi...
5,870
Transcatheter implantation of an aortic valve: anesthesiological management.
Transcatheter aortic valve implantation (TAVI) is an emergent alternative technique to surgery in high-risk patients with aortic stenosis. Here, we describe the anesthesiological management of patients undergoing TAVI at our institution over an 18-month period.</AbstractText>After a proper assessment of surgical risk a...
5,871
Case report: nonarrhythmogenic right ventricular dysplasia presenting with severe right ventricular failure in an adolescent.
Right ventricular dysplasia is usually discovered by the presence of ventricular arrhythmia. As arrhythmia is an epiphenomenon, the first presentation of some cases can be primarily heart failure. We describe an adolescent girl who presented with progressive right heart failure and whose hallmark was fibrofatty replace...
5,872
Management and comorbidities of atrial fibrillation in patients admitted in cardiology service in Kosovo-a single-center study.
Atrial fibrillation (AF) is the most important risk factor for ischemic stroke. Anticoagulation therapy can substantially decrease the risk of stroke in patients with AF. The aim of our study was to investigate the patient's comorbidities and management of patients with AF on the discharge.</AbstractText>From 5382 cons...
5,873
Comparative study of nifekalant versus amiodarone for shock-resistant ventricular fibrillation in out-of-hospital cardiopulmonary arrest patients.
In Japan, intravenous nifekalant (NIF) was often used for direct current cardioversion-resistant ventricular fibrillation (VF), until the use of intravenous amiodarone (AMD) was approved in 2007. The defibrillatory efficacy of NIF and AMD has thus far not been compared for resuscitation.</AbstractText>Between August 20...
5,874
Clinical applications and acute hepatotoxicity of intravenous amiodarone.
This cross-sectional, retrospective study was designed to evaluate the current clinical applications and acute hepatotoxicity of intravenous amiodarone administration at a hospital in China. Clinical data were collected from 1214 patients receiving intravenous amiodarone treatment between October 2003 and September 200...
5,875
Optimization of repolarization during biventricular pacing: a new target in patients with biventricular devices?
Evaluation of repolarization during sequentional biventricular pacing.</AbstractText>Patients with biventricular devices, and left ventricular leads placed to the basal part of lateral left ventricular wall were enrolled. QRS, QTc, JTc, and corrected Tpeak-Tend intervals were compared during sequentional biventricular,...
5,876
Right ventricular histological substrate and conduction delay in patients with Brugada syndrome.
The reported pathogenesis of Brugada syndrome is phase 2 reentry resulting from shortening of the epicardial action potential duration at the right ventricular outflow tract (RVOT). However, several studies have revealed a high incidence of ventricular late potentials and high rate of ventricular fibrillation (VF) indu...
5,877
[Morphology of acute myocardial infarction at prenecrotic stage].
We studied morphological changes of myocardium and content of glucose, potassium, calcium, sodium in pericardial fluid in persons who died suddenly of myocardial infarction at its prenecrotic stage at prehospital phase. It was established that acute myocardial infarction at prenecrotic stage can run in 2 morphological ...
5,878
Patient expectations from implantable defibrillators to prevent death in heart failure.
Indications for implantable cardioverter-defibrillators (ICDs) in heart failure (HF) are expanding and may include more than 1 million patients. This study examined patient expectations from ICDs for primary prevention of sudden death in HF.</AbstractText>Study participants (n = 105) had an EF &lt;35% and symptomatic H...
5,879
Reducing QT liability and proarrhythmic risk in drug discovery and development.
Drug-induced torsades de pointes (TdP), a rare, life-threatening, polymorphic, ventricular tachycardia associated with prolongation of the QT interval, has been the main safety reason for the withdrawal of medicines from clinical use over the last decade. Most often, drugs that prolong the action potential and delay ve...
5,880
[Severe coronary artery spasm immediately after aortic valve replacement].
We report a case of 72-year-old man with severe manifestations of coronary artery spasm immediately after aortic valve replacement (AVR), which was associated with hemodynamic and arrhythmic instability. The AVR was performed under mild hypothermic cardiopulmonary bypass (34 degrees C), and retrograde blood cardioplegi...
5,881
MMP-2 and TIMP-2 gene polymorphisms and susceptibility to atrial fibrillation in Chinese Han patients with hypertensive heart disease.
MMP-2 and TIMP-2 play important roles in the pathogenesis of arrhythmogenic atrial remodeling, and may contribute to the development and persistence of atrial fibrillation (AF). Functional polymorphisms in the promoter of MMP-2 and TIMP-2 gene may modulate an individual's susceptibility to AF.</AbstractText>A total of ...
5,882
Left atrial electromechanical conduction time can predict six-month maintenance of sinus rhythm after electrical cardioversion in persistent atrial fibrillation by Doppler tissue echocardiography.
The purpose of this study was to determine whether atrial electromechanical conduction time (EMT) measured by echocardiography can predict 6-month maintenance of sinus rhythm (SR) after electrical cardioversion in patients with atrial fibrillation (AF).</AbstractText>Fifty-three patients with persistent AF (&gt;1 month...
5,883
[Cardiac manifestations of patients with mitochondrial disease].
To analyze the cardiac manifestations of mitochondriopathy patients.</AbstractText>We retrospectively analyzed the clinical (Electrocardiogram, Holter monitoring, echocardiogram and laboratory examinations) and pathological data of 90 mitochondriopathy patients diagnosed within recent 20 years. The cardiac involvement ...
5,884
[Efficacy of cardiac resynchronization therapy for patients with refractory congestive heart failure].
To observe the efficacy of cardiac resynchronization therapy for patients with refractory congestive heart failure.</AbstractText>Thirty-one patients with refractory congestive heart failure received cardiac resynchronization therapy. Before operation, all patients received standard drug therapy (28 cases) or integrate...
5,885
Low-dose amiodarone for the prevention of atrial fibrillation after coronary artery bypass grafting in patients older than 70 years.
Atrial fibrillation (AF) is one of the most common arrhythmia after coronary artery bypass grafting (CABG), which not only increases the suffering of the patients, but also prolongs hospital stay and enhances cost of care, especially for patients older than 70 years. This study was designed to evaluate the efficacy and...
5,886
Survival after prolonged resuscitation with 99 defibrillations due to Torsade De Pointes cardiac electrical storm: a case report.
A 48-year-old previously healthy woman suffered witnessed cardiac arrest in hospital. She achieved return of spontaneous circulation and was transferred to the intensive care unit. During the following 3 hours, she suffered a cardiac electrical storm with 98 episodes of Torsade de Pointes ventricular tachycardia rapidl...
5,887
Perventricular closure of a large ventricular septal defect in congenitally corrected transposition of the great arteries.
We report the case of a 30 year-old male with congenitally corrected transposition of the great arteries, atrial, and ventricular septal defects (VSD), and pulmonary stenosis. He previously underwent three palliative surgical procedures before undergoing intracardiac repair at age 20 with a left ventricular to pulmonar...
5,888
Long-term follow up of secundum atrial septal defect closure with the amplatzer septal occluder.
During the past 15 years, closure of a secundum atrial septal defect (ASD) has moved from a surgical to a percutaneous transcatheter approach. Few long-term studies of the efficacy and safety of closure of an ASD by an Amplatzer septal occluder (ASO) exist.</AbstractText>To examine the long-term results of secundum ASD...
5,889
[Specific features of cardiac insufficiency in elderly patients with chronic renal disease].
To evaluate clinical features of chronic cardiac insufficiency (CCI) in elderly patients with renal dysfunction.</AbstractText>260 patents (143 men and 117 women) aged above 60 (mean 68.7 +/- 6.6) yr with I-IV FC CCI. 25 patients had hypertensive disease (HD), 30 coronary heart disease (CHD), 205 HD+CHD. Glomerular fil...
5,890
Ensuring the continuity of care of cardiorespiratory diseases at home. Monitoring equipment and medical data exchange over semantically annotated web services.
A significant portion of care related to cardiorespiratory diseases is provided at home, usually but not exclusively, after the discharge of a patient from hospital. It is the purpose of the present study to present the technical means which we have developed, in order to support the adaptation of the continuity of car...
5,891
Left atrial strain and strain rate in patients with paroxysmal and persistent atrial fibrillation: relationship to left atrial structural remodeling detected by delayed-enhancement MRI.
Atrial fibrillation (AF) is a progressive condition that begins with hemodynamic and/or structural changes in the left atrium (LA) and evolves through paroxysmal and persistent stages. Because of limitations with current noninvasive imaging techniques, the relationship between LA structure and function is not well unde...
5,892
Right coronary artery occlusion during RF ablation of typical atrial flutter.
Right coronary artery (RCA) occlusion and acute myocardial infarction are rare during radiofrequency (RF) ablation of the cavotricuspid isthmus. Ventricular fibrillation (VF) or cardiac arrest in the periprocedural period may be the initial or only clinical manifestation. Septal or lateral RF delivery may increase the ...
5,893
Plasma NT-proANP in patients with persistent atrial fibrillation who underwent successful cardioversion.
Atrial fibrillation (AF) decreases quality of life and significantly increases risk of stroke, congestive heart failure and death. Atrial overload and stretch also result in increased production of natriuretic peptide type A (ANP). The biologically inactive prohormone NT-proANP is released to plasma in the same amounts...
5,894
Availability of automated external defibrillators in the city of Warsaw - status for May 2009.
The most frequent cause of sudden cardiac arrest (SCA) is ventricular fibrillation and ventricular tachycardia. Despite many efforts the prognosis in this patient group is poor. According to the European Resuscitation Council (ERC) recommendations, early defibrillation, preferably in the first 3-5 min, is a key link in...
5,895
Hyperbaric oxygen preconditioning improves myocardial function, reduces length of intensive care stay, and limits complications post coronary artery bypass graft surgery.
The objective of this study was to determine whether preconditioning coronary artery disease (CAD) patients with HBO(2) prior to first-time elective on-pump cardiopulmonary bypass (CPB) coronary artery bypass graft surgery (CABG) leads to improved myocardial left ventricular stroke work (LVSW) post CABG. The primary en...
5,896
Attenuated recovery of heart rate turbulence early after myocardial infarction identifies patients at high risk for fatal or near-fatal arrhythmic events.
Autonomic dysfunction tends to improve over time after acute myocardial infarction (MI), but the clinical significance of autonomic remodeling is not well known.</AbstractText>The purpose of this study was to test the hypothesis that the amount of recovery of autonomic function early after MI is associated with a risk ...
5,897
Atrial electrophysiological and structural remodeling in high-risk patients with Brugada syndrome: assessment with electrophysiology and echocardiography.
Atrial fibrillation (AF) often occurs in Brugada syndrome (BrS), and BrS patients with spontaneous AF often experience ventricular fibrillation (VF) attacks. Atrial vulnerability providing a substrate for AF is known to be enhanced in BrS, but there are no data on atrial structural attributes.</AbstractText>The objecti...
5,898
In-flight automated external defibrillator use and consultation patterns.
Limited information exists about the in-flight use and outcomes associated with automated external defibrillators (AEDs) on commercial airlines.</AbstractText>To describe the characteristics and outcomes of AED use during in-flight emergencies including in-flight cardiac arrest and the associated ground medical consult...
5,899
[Defibrillation efficacy of a newly developed automated external defibrillator in a swine ventricular tachycardia/fibrillation model].
The aim of this study was to evaluate the recognition and defibrillation efficiency of a newly developed automated external defibrillator (AED).</AbstractText>Ventricular tachycardia (VT)/ventricular fibrillation (VF) was induced by alternating current (50 Hz) through an electrode placed on apex of right ventricle in 2...