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5,900 | [Plasma endothelin level in hypertensive patients receiving standard anti-hypertensive therapy with or without statins]. | To observe the association between plasma endothelin (ET) concentration and blood pressure level in essential hypertensive (EH) patients with or without complications and possible impact of statins on ET concentration.</AbstractText>From Sep 2007 to Mar 2009, 149 patients with EH were analyzed [44 EH, 40 EH complicated... |
5,901 | Recurrent left ventricular myxoma presenting as cerebrovascular accidents in a teenage girl. | Myxoma cordis is the most frequent primary cardiac tumour in adults. Paediatric primary cardiac tumours are rare, the most common type being rhabdomyoma. Atrial and ventricular myxomas occur infrequently in the paediatric age group. Intracardiac myxomas are seen with an estimated incidence of 0.5 per million population... |
5,902 | Atrial electroanatomical remodeling as a determinant of different outcomes between two current ablation strategies: circumferential pulmonary vein isolation vs pulmonary vein isolation. | The purpose of this study was to investigate the relationship between the efficacy of the 2 different ablation techniques of atrial fibrillation (AF) and left atrial (LA) size.</AbstractText>A total of 81 patients with paroxysmal AF (n = 58) or persistent AF (n = 23) refractory to antiarrhythmic drugs underwent circumf... |
5,903 | Recent advances in the pharmacological treatment of cardiac arrythmias. | Atrial and ventricular arrhythmias are associated with substantial morbidity and mortality and thus are a significant economic burden for healthcare systems. Currently available pharmacological agents have limited efficacy or the risk of relevant side effects, such as drug toxicity and proarrhythmic potential. Recent s... |
5,904 | Ganglionic plexus ablation during pulmonary vein isolation--predisposing to ventricular arrhythmias? | Catheter ablation is increasingly used to treat patients with atrial fibrillation (AF). Ablation of ganglionic plexi is often performed to reduce vagal innervation and has been shown to confer a better long-term outcome in terms of AF recurrence. We report a case of a patient having AF ablation with a profound vagal re... |
5,905 | Congenital short QT syndrome. | The Short QT Syndrome is a recently described new genetic disorder, characterized by abnormally short QT interval, paroxysmal atrial fibrillation and life threatening ventricular arrhythmias. This autosomal dominant syndrome can afflict infants, children, or young adults; often a remarkable family background of cardiac... |
5,906 | Fracture of epicardial resynchronization lead caused by deceleration injury. | A 50-year-old man with heart failure, systolic dysfunction, and abnormal septal motion underwent ventricular resynchronization. Postoperative clinical and echocardiographic improvement was observed. Several months later, he complained of worsening functional class after a traffic accident. Pacing lead fracture was diag... |
5,907 | Imaging and atrial fibrillation: the role of multimodality imaging in patient evaluation and management of atrial fibrillation. | Atrial fibrillation (AF) is the most common cardiac arrhythmia, and is associated with an increased risk of cardiac morbidity and mortality. In this review, the role of multimodality imaging in the evaluation and treatment of AF is discussed in two main parts. First, an overview of the initial assessment of an AF patie... |
5,908 | A spontaneous Type 1 electrocardiogram pattern in lead V2 is an independent predictor of ventricular fibrillation in Brugada syndrome. | Risk stratification for Brugada syndrome remains controversial. We investigated the relationships between episodes of ventricular fibrillation (VF) and various clinical, electrocardiographic, electrophysiologic, and genetic parameters both retrospectively and prospectively.</AbstractText>Fifty-two patients with Brugada... |
5,909 | Predictors of survival from out-of-hospital cardiac arrest: a systematic review and meta-analysis. | Prior studies have identified key predictors of out-of-hospital cardiac arrest (OHCA), but differences exist in the magnitude of these findings. In this meta-analysis, we evaluated the strength of associations between OHCA and key factors (event witnessed by a bystander or emergency medical services [EMS], provision of... |
5,910 | Improving outcome after out-of-hospital cardiac arrest by strengthening weak links of the local Chain of Survival; quality of advanced life support and post-resuscitation care. | Survival after out-of-hospital cardiac arrest (OHCA) depends on a well functioning Chain of Survival. We wanted to assess if targeted attempts to strengthen the weak links of our local chain; quality of advanced life support (ALS) and post-resuscitation care, would improve outcome.</AbstractText>Utstein data from all O... |
5,911 | Transthoracic defibrillation potential gradients in a closed chest porcine model of prolonged spontaneous and electrically induced ventricular fibrillation. | The purpose of this study was to measure the local electrical field or potential gradient, measured with a catheter-based system, required to terminate long duration electrically or ischaemically induced ventricular fibrillation (VF). We hypothesized that prolonged ischaemic VF would be more difficult to terminate when... |
5,912 | Discriminating the effect of accelerated compression from accelerated decompression during high-impulse CPR in a porcine model of cardiac arrest. | Piston based mechanical chest compression devices deliver compressions and decompressions in an accelerated pattern, resulting in superior haemodynamics compared to manual compression in animal studies. The present animal study compares haemodynamics during two different hybrid compression patterns to a standard compre... |
5,913 | Efficacy of a novel bipolar radiofrequency ablation device on the beating heart for atrial fibrillation ablation: a long-term porcine study. | Over recent years, a variety of energy sources have been used to replace the traditional incisions of the Cox maze procedure for the surgical treatment of atrial fibrillation. This study evaluated the safety and efficacy of a new bipolar radiofrequency ablation device for atrial ablation in a long-term porcine model.</... |
5,914 | Clinical characteristics and outcomes of heart failure with preserved ejection fraction: lessons from epidemiological studies. | Recent epidemiological studies have demonstrated that nearly half of all patients with heart failure (HF) have preserved left ventricular ejection fraction (HFPEF). Compared to those with reduced EF, patients with HFPEF are older, more likely to be women, less likely to have coronary artery disease, and more likely to ... |
5,915 | Catheter ablation of atrial fibrillation guided by complex fractionated atrial electrogram mapping of atrial fibrillation substrate. | Cardiologists and physicians have witnessed a significant change in the management of atrial fibrillation (AF): antiarrhythmic agents are no longer considered more effective than just merely using compounds that control ventricular response of the arrhythmia with anticoagulation in high-risk patients. Catheter ablation... |
5,916 | Delayed thrombolysis in a patient presenting after 12 hours of chest pain, cardiogenic shock and life-threatening arrhythmias. | This 63 years old man presented to the emergency room with chest pain of more than 12 hours duration. The initial electrocardiogram showed as ST segment elevation inferior and right ventricular infarction. He developed signs and symptoms consistent with cardiogenic shock, followed by life threatening ventricular fibril... |
5,917 | [Stress cardiomyopathy, a topical cardiac disorder]. | Stress cardiomyopathy (Tako-Tsubo, Broken Heart syndrome, or apical ballooning syndrome) was recently recognized as a distinct clinical entity. The aims of this review are to define this acute and reversible cardiomyopathy and to list its major clinical, biological and angiographic features. We performed a Medline scan... |
5,918 | Current review of Brugada syndrome: from epidemiology to treatment. | Brugada syndrome is a genetic cause of sudden cardiac arrest characterized by abnormal electrocardiographic (ECG) pattern in the right precordial leads either at rest or after provocation. In this condition, sudden death may occur due to polymorphic ventricular tachycardia or ventricular fibrillation. In approximately ... |
5,919 | Coupled pacing improves left ventricular function during simulated atrial fibrillation without mechanical dyssynchrony. | Electrical stimulation [coupled pacing (CP)] applied near the end of the T-wave is able to create a retrograde activation of the atrioventricular (AV) node in turn to prevent rapid ventricular conduction during atrial fibrillation (AF). The impact of this pacing modality associated with cardiac resynchronization therap... |
5,920 | The development of heart failure in patients with diabetes mellitus and pre-clinical diastolic dysfunction a population-based study. | The purpose of this study was to evaluate the outcomes of pre-clinical diastolic dysfunction in diabetic patients.</AbstractText>Studies have reported a high prevalence of pre-clinical diastolic dysfunction among patients with diabetes mellitus.</AbstractText>We identified all diabetic patients with a tissue Doppler im... |
5,921 | A critical decrease in dominant frequency and clinical outcome after catheter ablation of persistent atrial fibrillation. | Termination of persistent atrial fibrillation (AF) by radiofrequency ablation (RFA) is associated with a high probability of freedom from AF but requires extensive ablation and long procedure times.</AbstractText>The purpose of this study was to determine whether a critical decrease in the dominant frequency (DF) of AF... |
5,922 | Cardiac manifestations of neuromuscular disorders in children. | Cardiac abnormalities occur in association with many of the neuromuscular disorders that present in childhood. Genetic defects involving the cytoskeleton, nuclear membrane, and mitochondrial function have all been described in patients with skeletal myopathy and cardiac involvement. The most common classes of neuromusc... |
5,923 | Successful cardiopulmonary resuscitation in pregnancy: a case report. | The management of cardiac arrest in pregnancy is an important task for the emergency physicians. The clinical outcome of mother or fetus will often depend on the successful resuscitation of the first few minutes. Furthermore, the resuscitation team leader should consider the necessity of emergency hysterotomy (cesarean... |
5,924 | Catheter ablation of stable ventricular tachycardia before defibrillator implantation in patients with coronary heart disease (VTACH): a multicentre randomised controlled trial. | In patients with ventricular tachycardia (VT) and a history of myocardial infarction, intervention with an implantable cardioverter defibrillator (ICD) can prevent sudden cardiac death and thereby reduce total mortality. However, ICD shocks are painful and do not provide complete protection against sudden cardiac death... |
5,925 | Ventricular fibrillation initiated by an electrocution injury and terminated by an implantable cardioverter-defibrillator. | A 52-year-old man with an implantable cardioverter-defibrillator (ICD) was accidentally electrocuted when a flagpole he was erecting contacted an overhead electrical power line. The electrocution injury initiated ventricular fibrillation. The ICD sensed the arrhythmia and delivered therapy, converting his rhythm to sin... |
5,926 | [Which therapy for which patient? In daily practice]. | Although the important progress in the curative treatment of atrial fibrillation, the indications of the regularisation of the first episode and of the preventive treatment remain difficult. Without real proofs on the interest of maintain in sinus rhythm, the indications depend on the age of the patient, the clinical t... |
5,927 | [Rate control in patients with atrial fibrillation]. | The objectives of rate control in patients with atrial fibrillation is to reduce symptoms, improve quality of live and minimize the risk of heart failure development. Based upon results of large randomized studies, this strategy can be chosen as a first line therapy in some patients including those with heart failure. ... |
5,928 | [Silent atrial fibrillation]. | Asymptomatic atrial fibrillation (AF) is common, may adversely affect quality of life, and above all can be as serious as symptomatic AF. The prevalence of AF reported in epidemiological studies is significantly underestimated, as asymptomatic AF is often not known about. The efficacy of pharmacological or non-pharmaco... |
5,929 | Prediction of appropriate defibrillator therapy in heart failure patients treated with cardiac resynchronization therapy. | The necessity of implantable cardioverter-defibrillator (ICD) implantation in patients with systolic heart failure (HF) who undergo cardiac resynchronization therapy (CRT) may be questioned. The aim of this study was to identify patients at low risk for sustained ventricular arrhythmia. One hundred sixty-nine consecuti... |
5,930 | Intraoperative defibrillation threshold testing during implantable cardioverter-defibrillator insertion: do we really need it? | The assessment of defibrillation efficacy using a safety margin of 10 J has long been the standard of care for insertion of implantable cardioverter-defibrillator (ICD), but physicians are concerned about complications related to induction test. Therefore, the need for testing has been recently questioned. The aim of o... |
5,931 | Hypertrophic cardiomyopathy in the elderly. | Hypertrophic cardiomyopathy (HCM) is a relatively common genetic cardiac disorder with heterogeneous morphological, functional and clinical features. Although the risk of sudden death and incapacitating symptoms in young patients has been focused upon, the disease has been found with increasing frequency in elderly pat... |
5,932 | Cardiac arrest caused by undersensing of a temporary epicardial pacemaker. | The R-on-T phenomenon is a well-known entity that predisposes to dangerous arrhythmias. Typically, a premature ventricular complex occurring at the critical time during the T wave of the preceding beat precipitates ventricular tachycardia and fibrillation. This phenomenon can occur not only in asynchronous ventricular ... |
5,933 | Long-term prognosis of patients diagnosed with Brugada syndrome: Results from the FINGER Brugada Syndrome Registry. | Brugada syndrome is characterized by ST-segment elevation in the right precordial leads and an increased risk of sudden cardiac death (SCD). Fundamental questions remain on the best strategy for assessing the real disease-associated arrhythmic risk, especially in asymptomatic patients. The aim of the present study was ... |
5,934 | Severe lactic acidosis after an iatrogenic propylene glycol overdose. | Propylene glycol is a diluent found in many intravenous and oral drugs, including phenytoin, diazepam, and lorazepam. Propylene glycol is eliminated from the body by oxidation through alcohol dehydrogenase to form lactic acid. Under normal conditions, the body converts lactate to pyruvate and metabolizes pyruvate throu... |
5,935 | Mechanical mitral valve thrombosis and giant left atrial thrombus: comparison of transesophageal echocardiography and 64-slice multidetector computed tomography. | We report on the use of multidetector computed tomography (MDCT) in the diagnosis of prosthetic heart valve thrombosis and a giant left atrial (LA) thrombus extending into the LA appendage (LAA), in comparison with findings of transesophageal echocardiography (TEE). A 52-year-old woman with an eight-year history of mec... |
5,936 | [Cardiac arrest due to accidental hypothermia and prolonged cardiopulmonary resuscitation]. | In cardiac arrest produced by accidental hypothermia, cardiopulmonary resuscitation must be prolonged until normal body temperature is achieved. There are different rewarming methods. In theory, the more invasive ones are elective in patients with cardiac arrest because of their higher rewarming speed. However, it has ... |
5,937 | [Results of the first year of experience of the cardiopulmonary resuscitation program "Juan Ramón Jiménez" Hospital (Huelva)]. | To present the results of the first year of the functioning of a Cardiopulmonary Resuscitation (CPR) Hospital Plan and to describe the characteristics of the patients with cardiopulmonary arrest (CPA) in hospital units with no monitoring facilities (HU).</AbstractText>An observational, prospective study in a cohort of ... |
5,938 | A case of fatal caffeine poisoning. | Caffeine is a natural alkaloid methylxanthine that is found in various plants such as coffee or tea. Symptoms of a severe overdose may present with hypokalemia, hyponatremia, ventricular arrhythmias, hypertension followed by hypotension, respiratory failure, seizures, rhabdomyolysis, ventricular fibrillation and finall... |
5,939 | [A simulation study of the effects of ischemia on spiral waves in 2D human ventricular tissue]. | Based on human ventricular single cell mathematical model, a two-dimensional mesh of ventricular wall tissue was constructed. Through the increasing of the concentration of extracellular K+, we simulated the propagation of spiral wave in a condition under the influence of ischemia in 2-D human ventricular tissue. The r... |
5,940 | Self assessment exercises in Intensive Care Medicine. | Intensive Care Medicine (ICM) is no longer the exclusive preserve of anaesthetists as both emergency medicine and general medicine trainees now also train in this increasingly important speciality. This edition of the JRAMC self assessment question series serves to cover some of the current 'hot topics' in ICM and enab... |
5,941 | Transmural dispersion of repolarization in failing and nonfailing human ventricle. | Transmural dispersion of repolarization has been shown to play a role in the genesis of ventricular tachycardia and fibrillation in different animal models of heart failure (HF). Heterogeneous changes of repolarization within the midmyocardial population of ventricular cells have been considered an important contributo... |
5,942 | Efficacy of continuous positive airway pressure on arrhythmias in obstructive sleep apnea patients. | The purpose of this study was to determine the relationship between obstructive sleep apnea (OSA) and cardiovascular disorders in a large Japanese population, and to assess the efficacy of continuous positive airway pressure (CPAP) in the treatment of OSA-associated arrhythmias. The study population comprised 1394 Japa... |
5,943 | Stenting and surgery for coronary vasospasm : the wrong solution fails to solve the problem. | A 55-year-old man, with a history of medically uncontrolled coronary vasospasm, presented for evaluation of chest pain 6 months after implantation of left internal mammary artery. Due to recurrent episodes of vasospastic angina and serious complications of coronary spasm (ventricular fibrillation, myocardial infarction... |
5,944 | [Ventricular tachycardias originating in the his-purkinje system. Bundle branch reentrant ventricular tachycardias and fascicular ventricular tachycardias]. | Ventricular tachycardias (VT) associated with the His-Purkinje system may occur in patients with and without organic heart disease. The former may encounter bundle branch reentrant VT, a macroreentrant VT utilizing the specific conduction system. It frequently occurs in patients with preexisting conduction disturbance ... |
5,945 | [Limits and scopes of invasive risk stratification. Do we still need programmed ventricular stimulation?]. | Patients with ischemic heart disease and left ventricular systolic dysfunction (ICM), dilated (DCM), hypertrophic (HCM), or arrhythmogenic right ventricular cardiomyopathy (ARVCM) carry a high risk of sudden cardiac death (SCD). Ventricular tachyarrhythmias are most often the cause of SCD, which can be treated with int... |
5,946 | Correlates of NT-proBNP concentration in patients with essential hypertension in absence of congestive heart failure. | N-terminal proBNP (NT-proBNP) is widely used as a diagnostic biomarker and for the risk stratification of patients with heart failure (HF). Its role in the evaluation of patients with essential hypertension (EHT) is less clear. We examined the relationship between NT-proBNP concentrations and various clinical character... |
5,947 | A Dutch case of a takotsubo cardiomyopathy after pacemaker implantation. | An 83-year-old female patient with symptomatic atrial fibrillation was referred to the Department of Cardiology for a scheduled electrocardioversion. Because of a junctional escape rhythm after the electrocardioversion she received a DDD pacemaker which was complicated by dyspnoea and ST-segment elevations in the infer... |
5,948 | A clinical comparison between a new dual-chamber pacing mode-AAIsafeR and DDD mode. | The aim of this study was to compare the cross-follow-up results in DDD or AAISafeR mode and to describe the safety and effectiveness of this pacing mode.</AbstractText>The Symphony 2450/2550 cardiac pacemakers were implanted in 30 patients with sick sinus syndrome between February 2006 and September 2006. They were ra... |
5,949 | Intermediate-term effects of transcatheter secundum atrial septal defect closure on cardiac remodeling in children and adults. | The study aimed to investigate the intermediate-term effects of transcatheter atrial septal defect (ASD) closure on cardiac remodeling in children and adult patients. Between December 2003 and February 2009, 117 patients (48 males, 50 adults) underwent transcatheter ASD closure with the Amplatzer septal occluder (ASO).... |
5,950 | Abnormal restitution property of action potential duration and conduction delay in Brugada syndrome: both repolarization and depolarization abnormalities. | This study sought to examine the action potential duration restitution (APDR) property and conduction delay in Brugada syndrome (BrS) patients. A steeply sloped APDR curve and conduction delay are known to be important determinants for the occurrence of ventricular fibrillation (VF).</AbstractText>Endocardial monophasi... |
5,951 | Increase in pre-shock pause caused by drug administration before defibrillation: an observational, full-scale simulation study. | The importance of circulation during cardiopulmonary resuscitation has led to efforts to decrease time without chest compressions ("no-flow time"). The no-flow time from the interruption of chest compressions until defibrillation is referred to as the "pre-shock pause". A shorter pre-shock pause increases the chance of... |
5,952 | Monitoring in resuscitation: comparison of cardiac output measurement between pulmonary artery catheter and NICO. | The cardiac output and coronary perfusion pressure generated from chest compressions during resuscitation manoeuvres can predict effectiveness and successful outcome. Until now, there is no good method for haemodynamic monitoring during resuscitation. Noninvasive partial carbon dioxide rebreathing system (NICO, Novamet... |
5,953 | Deaths in custody: are some due to electronic control devices (including TASER devices) or excited delirium? | Deaths have occurred after law-enforcement incidents involving applications of electronic control devices (ECDs) (including TASER devices). An "excited delirium" syndrome (reported in the literature prior to the development of ECDs currently in use), however, includes several factors that may be related to such deaths ... |
5,954 | Diabetes is associated with impaired myocardial performance in patients without significant coronary artery disease. | Patients with diabetes mellitus (DM) have high risk of heart failure. Whether some of the risk is directly linked to metabolic derangements in the myocardium or whether the risk is primarily caused by coronary artery disease (CAD) and hypertension is incompletely understood. Echocardiographic tissue Doppler imaging was... |
5,955 | Advanced age, low left atrial appendage velocity, and factor V promoter sequence variation as predictors of left atrial thrombosis in patients with nonvalvular atrial fibrillation. | Atrial fibrillation (AF) renders individual patients at risk for development of an atrial thrombus. The aim of this study was to determine clinical and echocardiographic factors influencing the risk of left atrial thrombosis (LAT) in patients with persistent nonvalvular AF. Genetic variants encoding haemostatic factors... |
5,956 | Novel pharmacological approaches for antiarrhythmic therapy. | Arrhythmias are caused by the perturbation of physiological impulse formation, impaired conduction, or disturbed electrical recovery. Currently available antiarrhythmic drugs-perhaps with exception of amiodarone-are not sufficiently effective and are burdened by cardiac and extracardiac side effects that may offset the... |
5,957 | The usefulness of minimal ventricular pacing and preventive AF algorithms in the treatment of PAF: the 'MinVPace' study. | The beneficial effects of atrial pacing on the incidence, duration and symptomatology of paroxysmal atrial fibrillation (PAF) may be negated by increased ventricular pacing. This prospective randomised study evaluates the effect of pacing algorithms that minimise ventricular pacing (MinVP) with and without anti-AF algo... |
5,958 | A case report of central extracorporeal membrane oxygenation after implantation of a left ventricular assist system: femoral vein and left atrium cannulation for ECMO. | The left ventricular assist system (LVAS) is often used for end-stage heart failure. However, in severe lung disorder, the patient needs extracorporeal membrane oxygenation (ECMO) because oxygenation using only a ventricular assist system (VAS) is insufficient. We report a successful case of combining the use of LVAS a... |
5,959 | Survival and neurological outcomes after nasopharyngeal cooling or peripheral vein cold saline infusion initiated during cardiopulmonary resuscitation in a porcine model of prolonged cardiac arrest. | We have previously demonstrated that nasopharyngeal cooling initiated during cardiopulmonary resuscitation improves the success of resuscitation. In this study, we compared the effects of nasopharyngeal cooling with cold saline infusion initiated during cardiopulmonary resuscitation on resuscitation outcome in a porcin... |
5,960 | Leaning during chest compressions impairs cardiac output and left ventricular myocardial blood flow in piglet cardiac arrest. | Complete recoil of the chest wall between chest compressions during cardiopulmonary resuscitation is recommended, because incomplete chest wall recoil from leaning may decrease venous return and thereby decrease blood flow. We evaluated the hemodynamic effect of 10% or 20% lean during piglet cardiopulmonary resuscitati... |
5,961 | Correlation between myocardial fibrosis and the occurrence of atrial fibrillation in hypertrophic cardiomyopathy: a cardiac magnetic resonance imaging study. | Cardiac magnetic resonance imaging (CMR) in hypertrophic cardiomyopathy (HCM) often shows delayed contrast enhancement (DE) representing regions of focal myocardial fibrosis. Atrial fibrillation (AF) is a commonly reported complication of HCM. We determined the relationship between the presence of left ventricular myoc... |
5,962 | Ablation vs medical therapy in the setting of symptomatic atrial fibrillation and left ventricular dysfunction. | Small, single-center studies suggest that catheter ablation of atrial fibrillation (AF) can improve ventricular function and reduce symptoms in patients with left ventricular (LV) dysfunction. However, ablation has not been compared with a pharmacologic strategy for AF. The authors evaluated patients with AF and sympto... |
5,963 | The atrial fibrillation paradox of heart failure. | The prevalence of atrial fibrillation (AF) in patients with heart failure (HF) is high, but longitudinal studies suggest that the incidence of AF is relatively low. The authors investigated this paradox prospectively in an epidemiologically representative population of patients with HF and persistent AF. In all, 891 co... |
5,964 | The usefulness of microvolt T-wave alternans in the risk stratification of patients with hypertrophic cardiomyopathy. | Patients with hypertrophic cardiomyopathy are prone to ventricular arrhythmias and sudden death. Identifying patients at risk of sudden death is difficult.</AbstractText>To determine whether microvolt T-wave alternans detected during exercise or rapid atrial pacing can identify patients with HCM who are at risk of vent... |
5,965 | Intrapericardial ranolazine prolongs atrial refractory period and markedly reduces atrial fibrillation inducibility in the intact porcine heart. | Extensive experimental studies and clinical evidence (Metabolic Efficiency with Ranzolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndrome Thrombolysis in Myocardial Infarction-36 [MERLIN TIMI-36] trial) indicate potential antiarrhythmic efficacy of the antianginal agent ranolazine. Delivery of agents in... |
5,966 | Distribution of pre-course BLS/AED manuals does not influence skill acquisition and retention in lay rescuers: a randomised study. | The present study aims to investigate whether the distribution of the Basic Life Support and Automated External Defibrillation (BLS/AED) manual, 4 weeks prior to the course, has an effect on skill acquisition, theoretical knowledge and skill retention, compared with courses where manuals were not distributed.</Abstract... |
5,967 | Prevention of atrial fibrillation in cardiac surgery: time to consider a multimodality pharmacological approach. | Atrial fibrillation (AF) is very common within the first 5 days of cardiac surgery. It is associated with significant morbidity including stroke, ventricular arrhythmias, myocardial infarction, heart failure, acute kidney injury, prolonged hospital stay, and also short- and long-term mortality. The underlying mechanism... |
5,968 | Palliative atrial switch operation in a 22-year-old patient with transposition of the great arteries. | A 2-year-old boy was diagnosed as having transposition of the great arteries (TGA) and ventricular septal defect (VSD) and underwent pulmonary artery banding. The patient showed slow progression of cyanosis and dyspnea on exertion. Oxygen saturation was 70-75 % and cardiac catheterization showed severe pulmonary hypert... |
5,969 | Detrended fluctuation analysis predicts successful defibrillation for out-of-hospital ventricular fibrillation cardiac arrest. | Repeated failed shocks for ventricular fibrillation (VF) in out-of-hospital cardiac arrest (OOHCA) can worsen the outcome. It is very important to rapidly distinguish between early and late VF. We hypothesised that VF waveform analysis based on detrended fluctuation analysis (DFA) can help predict successful defibrilla... |
5,970 | Electrical storm in patients with implantable cardioverter-defibrillators: can it be forecast? | The aim of this retrospective study was to determine the prevalence and predictors of electrical storm in 227 patients who had received implantable cardioverter-defibrillators (ICDs) and had been monitored for 31.7 +/- 15.6 months. Of these, 174 (77%) were men. The mean age was 55.8 +/- 15.5 years (range, 20-85 yr), an... |
5,971 | [Role of ACE-inhibitors in preventing atrial fibrillation relapses in normotensive patients]. | Atrial fibrillation (AF) is the most common chronic cardiac arrhythmia and a major public health problem, leading to high rates of morbidity and mortality. The most prevalent cause of AF in the western world is hypertensive heart disease. Blood pressure increase leads to hemodynamic modifications which usually have dir... |
5,972 | 2-year survival of patients undergoing mild hypothermia treatment after ventricular fibrillation cardiac arrest is significantly improved compared to historical controls. | Therapeutic hypothermia has been proven to be effective in improving neurological outcome in patients after cardiac arrest due to ventricular fibrillation (VF). Data concerning the effect of hypothermia treatment on long-term survival however is limited.</AbstractText>Clinical and outcome data of 107 consecutive patien... |
5,973 | Estimating the probability that the Taser directly causes human ventricular fibrillation. | This paper describes the first methodology and results for estimating the order of probability for Tasers directly causing human ventricular fibrillation (VF). The probability of an X26 Taser causing human VF was estimated using: (1) current density near the human heart estimated by using 3D finite-element (FE) models;... |
5,974 | Therapeutic hypothermia with immunosuppressive drugs for a comatose renal transplant patient who survived out-of-hospital cardiac arrest. | A 31-year-old man suddenly collapsed at work. His colleagues witnessed the event, applied basic life support, and called for an ambulance. After the ambulance arrived, the initial rhythm was confirmed as ventricular fibrillation (VF) and he was defibrillated with an automated external defibrillator. Spontaneous circula... |
5,975 | Unusual presentation of thyrotoxicosis as complete heart block and renal failure: a case report. | Thyrotoxicosis is a clinical entity often very difficult to diagnose without biochemical confirmation as its clinical features can be highly varied. The most common cardiac manifestations of thyrotoxicosis are resting sinus tachycardia, supraventricular tachycardia including atrial fibrillation and atrial flutter with ... |
5,976 | Repair of ventricle free wall rupture after acute myocardial infarction: a case report. | Acute myocardial infarction (AMI) may culminate in sudden death by ventricular fibrillation, cardiogenic shock, and cardiac rupture. We present a case of postinfarction rupture treated by direct closure and coronary artery bypass grafting after thrombolytic therapy.</AbstractText>A 67-year-old woman with cardiac risk f... |
5,977 | Genetic variation in SCN10A influences cardiac conduction. | To identify genetic factors influencing cardiac conduction, we carried out a genome-wide association study of electrocardiographic time intervals in 6,543 Indian Asians. We identified association of a nonsynonymous SNP, rs6795970, in SCN10A (P = 2.8 x 10(-15)) with PR interval, a marker of cardiac atrioventricular cond... |
5,978 | Purkinje activation precedes myocardial activation following defibrillation after long-duration ventricular fibrillation. | While reentry within the ventricular myocardium (VM) is responsible for the maintenance of short-duration ventricular fibrillation (SDVF; VF duration <1 minute), Purkinje fibers (PFs) are important in the maintenance of long-duration ventricular fibrillation (LDVF; VF duration >1 minute).</AbstractText>The purpos... |
5,979 | Left ventricular ejection fraction and absence of ACE inhibitor/angiotensin II receptor blocker predicts appropriate defibrillator therapy in the primary prevention population. | Implantable cardioverter defibrillators (ICD) significantly reduce mortality in patients with left ventricular (LV) dysfunction. However, little is known of the predictors of appropriate device activation in the primary prevention population. The aim of the present study was to determine predictors of appropriate devic... |
5,980 | High efficacy of disopyramide in the management of ventricular fibrillation storms in a patient with Brugada syndrome. | The patient was a 57-year-old man with Brugada syndrome, who had been implanted with a implantable cardioverter defibrillator (ICD). The frequency of ventricular fibrillation (VF) started to increase about 4 years after ICD implantation, occurring, at worst, six times in one night. Immediately after starting oral admin... |
5,981 | A decrease in serum aldosterone level is associated with maintenance of sinus rhythm after successful cardioversion of atrial fibrillation. | The activation of the renin-angiotensin-aldosterone system has been implicated in the progression of atrial structural remodeling during atrial fibrillation (AF). However, consequences of the changes of aldosterone in AF have not been evaluated.</AbstractText>This study's aim was to evaluate changes of serum aldosteron... |
5,982 | Twiddling with an implantable cardioverter-defibrillator. | A 64-year-old woman underwent implantation of a single-chamber implantable cardioverter-defibrillator. The active fixation lead was positioned in the right ventricular apex and the generator in a left pre-pectoral pocket. Device interrogation 4weeks after implantation revealed inappropriate sensing and failure of pacin... |
5,983 | Novel use of a subcutaneous shock lead to create an epicardial implantable cardioverter/defibrillator system via a limited thoracotomy. | We report the case of a novel use of a subcutaneous shock lead to create an epicardial implantable cardioverter/defibrillator (ICD) system via a limited thoracotomy in a patient with poor vascular access. Performance of the system is comparable to the conventional ICD system without the disadvantages of other available... |
5,984 | Does time delay between the primary cardiac arrest and PCI affect outcome? | In patients with acute ST-segment elevation acute myocardial infarction (AMI), no data are available on the prognostic value of cardiac arrest (CA) due to ventricular fibrillation (VF) before, during, and after percutaneous coronary intervention (PCI). The aim of our study was to determine differences in prognosis betw... |
5,985 | CaMKII-dependent diastolic SR Ca2+ leak and elevated diastolic Ca2+ levels in right atrial myocardium of patients with atrial fibrillation. | Although research suggests that diastolic Ca(2+) levels might be increased in atrial fibrillation (AF), this hypothesis has never been tested. Diastolic Ca(2+) leak from the sarcoplasmic reticulum (SR) might increase diastolic Ca(2+) levels and play a role in triggering or maintaining AF by transient inward currents th... |
5,986 | Ventricular safety pacing, ventricular sense response, and ventricular tachycardia. | The ventricular sense response (VSR) algorithm enforces biventricular pacing on ventricular sensing to maximize biventricular pacing in patients with atrial fibrillation. This report describes a case of recurrent ventricular tachycardia that may be facilitated by this enforced pacing algorithm. |
5,987 | [Case of myocardial infarction during emergency clipping surgery of a cerebral aneurysm]. | An 80-year-old woman with subarachnoid hemorrhage underwent emergency neck clipping of a cerebral aneurysm. She had previously undergone surgery for an abdominal aortic aneurysm 10 years before. Anesthesia was induced with propofol and maintained with a combination of fentanyl and sevoflurane (0.5-1.5%) in air and oxyg... |
5,988 | Ventricular fibrillation associated with use of synephrine containing dietary supplement. | As the prevalence of obesity increases in the United States, military personnel are turning to unregulated dietary supplements to aid in weight loss. Some of these supplements may cause more harm than benefit. We report the case of a 27-year-old active duty female who experienced an episode of ventricular fibrillation ... |
5,989 | Reduction of CPR artifacts in the ventricular fibrillation ECG by coherent line removal. | Interruption of cardiopulmonary resuscitation (CPR) impairs the perfusion of the fibrillating heart, worsening the chance for successful defibrillation. Therefore ECG-analysis during ongoing chest compression could provide a considerable progress in comparison with standard analysis techniques working only during "hand... |
5,990 | QRS complex abnormalities in subjects with idiopathic ventricular fibrillation. | Recent data point to a high incidence of early repolarization abnormalities among patients with idiopathic ventricular fibrillation (IVF). ECG data from 11 patients with idiopathic IVF were evaluated for the presence of initial (slurring or notching of the ascending limb of the R-wave that resembles a "pseudo" delta-wa... |
5,991 | Honoring Leslie A. Geddes - farewell .. | Honor thy father and thy mother, say the Holy Scriptures1, for they at least gave thee this biological life, but honor thy teachers, too, for they gave thee knowledge and example.Leslie Alexander Geddes took off on a long, long trip, Sunday October 25, 2009, leaving his body for medical and research use. The departing ... |
5,992 | Conduction delay in right ventricle as a marker for identifying high-risk patients with Brugada syndrome. | To evaluate the significance of conduction delay (CD) in the right ventricle (RV) in Brugada syndrome (BS) as a marker for risk stratification of sudden death.</AbstractText>Twenty-five patients with BS (7 with documented ventricular fibrillation (VF), 8 with syncope, and 10 without symptoms) and 10 control subjects we... |
5,993 | Assessment of reperfusion following thrombolysis with mean fibrillation and amplitude spectrum area in patients with sustained ventricular fibrillation. | Improved microcirculatory reperfusion in patients with ventricular fibrillation (VF) enhances the electrical activity of the fibrillation process and increases the likelihood of successful defibrillation.</AbstractText>Changes in amplitude spectrum area (AMSA) and mean fibrillation (MF) in patients with sustained VF we... |
5,994 | Caveat anicula! Beware of quiet little old ladies: demographic features, pharmacotherapy, readmissions and survival in a 10-year cohort of patients with heart failure and preserved systolic function. | To determine whether heart failure with preserved systolic function (HFPSF) has different natural history from left ventricular systolic dysfunction (LVSD).</AbstractText>A retrospective analysis of 10 years of data (for patients admitted between 1 July 1994 and 30 June 2004, and with a study census date of 30 June 200... |
5,995 | Performance of chest compressions by laypersons during the Public Access Defibrillation Trial. | Increasing evidence indicates that health professionals often may not achieve guideline standards for cardiopulmonary resuscitation (CPR). Little is known about layperson CPR performance.</AbstractText>The investigation was a retrospective cohort study of cardiac arrest patients treated by layperson CPR and one model o... |
5,996 | Treatment of patients with supraventricular tachyarrhythmias in a medical intensive care unit. | Direct-current cardioversion has a higher success rate than does medical therapy in converting supraventricular tachyarrhythmias to sinus rhythm and should be performed immediately in patients with hemodynamic instability. Hemodynamically stable patients with atrial fibrillation or atrial flutter, a rapid ventricular r... |
5,997 | Does syncope require rhythmic and non-rhythmic evaluation in patients with previous MI? | Multiple factors, in addition to left ventricular ejection fraction (LVEF) influence the risk of mortality in coronary artery disease. The purpose of this study was to evaluate the main causes of syncope after myocardial infarction (MI) and to propose an algorithm of management.</AbstractText>356 patients consecutively... |
5,998 | Dronedarone in the management of atrial fibrillation. | Atrial fibrillation is the most common type of tachyarrhythmia caused by multiple re-entrant wave forms within the atria and bombarding the atrioventricular node several times making it beat in a rapid, disorganized fashion termed "fibrillation". In atrial fibrillation, atria beat more than 300 times per minute. The ar... |
5,999 | Effects of α-methylnorepinephrine on cardiac function and myocardium at early stage of resuscitation in rabbits. | Recent studies have shown that α2-adrenergic agonists can reduce postresuscitation myocardial injury. This study was undertaken to observe changes of hemodynamics, myocardial injury markers cTnT and cardiac morphology by establishing a cardiopulmonary resuscitation model with rabbits, and to detect whether α... |
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