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8,400 | High plasma levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) and interleukin-8 (IL-8) characterize patients prone to ventricular fibrillation complicating myocardial infarction. | Atherosclerotic plaques prone to cause thrombotic complications and plaque rupture account for the majority of fatal myocardial infarctions (MI), which may be complicated by ventricular fibrillation (VF). Matrix-degrading metalloproteinases (MMPs) and their inhibitors (TIMPs) are expressed in atherosclerotic lesions an... |
8,401 | Cardiac memory induced by QRS widening due to propafenone toxicity. | Propafenone toxicity can cause significant QRS widening and markedly abnormal ventricular activation pattern. Aberrant ventricular activation upon its resolution is known to produce persistent T-wave changes known as "cardiac memory" (CM). A 74-year-old woman presented with a severely abnormal electrocardiogram consist... |
8,402 | Shocking truths about implantable cardioverter defibrillator monitoring zones. | A 36 year-old man with hypertrophic cardiomyopathy and an ATLAS + DR implantable cardioverter defibrillator (ICD) (St. Jude Medical, Inc., St. Paul, MN, USA) for primary prevention received a shock while cycling. The ventricular fibrillation detection threshold was 182 beats/min. An additional monitoring zone was progr... |
8,403 | An approach to ablate and pace:AV junction ablation and pacemaker implantation performed concurrently from the same venous access site. | Atrioventricular junction (AVJ) ablation combined with permanent pacemaker implantation (the "ablate and pace" approach) remains an acceptable alternative treatment strategy for symptomatic, drug-refractory atrial fibrillation (AF) with rapid ventricular response. This case series describes the feasibility and safety o... |
8,404 | Biventricular upgrading in patients with conventional pacing system and congestive heart failure: results and response predictors. | There are few studies on cardiac resynchronization therapy (CRT) in heart failure (HF) patients with preexisting right ventricular (RV) pacing. The purpose of this study was to determine the efficacy of CRT upgrading in RV-paced patients and the predictivity of electromechanical dyssynchrony parameters (EDP) evaluated ... |
8,405 | Sustained polymorphic arrhythmias induced by programmed ventricular stimulation have prognostic value in patients receiving defibrillators. | Patients with ischemic cardiomyopathy (ICM) who have monomorphic ventricular tachycardia (VT) induced by programmed ventricular stimulation (PVS) are at increased risk of sudden cardiac death (SCD). Among a primary prevention population, the prognostic significance of induced polymorphic ventricular arrhythmias is unkn... |
8,406 | [The application of 4-aminopyridine in calcium channel inhibitors acute poisoning]. | Calcium channel inhibitors have been extensively used to treat arterial hypertension, ischaemic heart disease and supraventricular rhythm irregularities. The poisonings by that category of drugs are extremely dangerous, particularly when accompanied by intoxication with other drugs affecting the circulatory function. T... |
8,407 | Can the direct cardiac effects of the electric pulses generated by the TASER X26 cause immediate or delayed sudden cardiac arrest in normal adults? | There is only a small amount of experimental data about whether the TASER X26, a nonlethal weapon that delivers a series of brief electrical pulses to cause involuntary muscular contraction to temporarily incapacitate an individual, can initiate ventricular fibrillation to cause sudden cardiac arrest either immediately... |
8,408 | Electrocardiographic and electrophysiologic characteristics in patients with Brugada type electrocardiogram and inducible ventricular fibrillation: single center experience. | The study examined the electrocardiographic and electrophysiologic characteristics in relation to programmed ventricular stimulation (PVS)-induced ventricular fibrillation (VF) in patients with Brugada syndrome.</AbstractText>Thirty-four patients with a Brugada-type electrocardiogram (ECG) were enrolled. Twelve patient... |
8,409 | Predictors of congestive heart failure in patients on maintenance hemodialysis. | Cardiovascular disease is a major cause of death in patients on maintenance hemodialysis (HD). Predictors of congestive heart failure (CHF) events in patients on HD were investigated, focusing on left ventricular (LV) function.</AbstractText>One hundred consecutive patients on HD were followed for at least 5 years afte... |
8,410 | Exercise training normalizes beta-adrenoceptor expression in dogs susceptible to ventricular fibrillation. | Previous studies demonstrated an enhanced beta(2)-adrenoceptor (AR) responsiveness in animals susceptible to ventricular fibrillation (VF) that was eliminated by exercise training. The present study investigated the effects of endurance exercise training on beta(1)-AR and beta(2)-AR expression in dogs susceptible to VF... |
8,411 | Autologous right atrial wall patch for closure of atrial septal defects. | We used the right atrial free wall as a patch to close atrial septal defects (ASD) and report its results.</AbstractText>Between July 1998 and April 2006, 87 patients (mean age, 21.9 +/- 13.9 years; range, 7 months to 54 years), underwent closure of ASD with an autologous right atrial free wall patch. The underlying di... |
8,412 | Atrial cardiomyocyte tachycardia alters cardiac fibroblast function: a novel consideration in atrial remodeling. | Atrial fibrillation (AF) causes tachycardia-induced atrial electrical remodeling, contributing to the progressive nature of the arrhythmia. Ventricular dysfunction due to a rapid response to AF can cause structural remodeling, but whether AF itself directly promotes atrial fibrosis is controversial. This study investig... |
8,413 | Risk factors and predictors of Torsade de pointes ventricular tachycardia in patients with left ventricular systolic dysfunction receiving Dofetilide. | The purpose of this study was to identify risk factors of Torsade de pointes (TdP) ventricular tachycardia in patients medicated with a class III antiarrhythmic drug (dofetilide) and left ventricular systolic dysfunction with heart failure (HF) or recent myocardial infarction (MI). The 2 Danish Investigations of Arrhyt... |
8,414 | Impact of ramipril on the incidence of atrial fibrillation: results of the Heart Outcomes Prevention Evaluation study. | We evaluated the effect of angiotensin-converting enzyme (ACE) inhibitor ramipril on the incidence of atrial fibrillation (AF) in patients enrolled in the Heart Outcomes Prevention Evaluation trial.</AbstractText>Atrial fibrillation is the most common arrhythmia affecting the general population and is associated with i... |
8,415 | Near death and neurocardiogenic syncope. | We report the case of an 18-year-old female who presented as an out-of-hospital ventricular fibrillation cardiac arrest. She required ICD insertion and recovered without deficit. Following recurrent syncopal episodes we diagnosed the co-existence of Neurocardiogenic syncope. |
8,416 | Acute myocardial infarction following the combined use of cocaine and alcohol. | We describe the case of a 37-year-old man who presented with inferior wall myocardial infarction shortly after the concomitant use of cocaine and ethanol. The patient showed prompt ST resolution after thrombolytic therapy. Within two hours from his arrival at the hospital the patient had an episode of ventricular fibri... |
8,417 | QT interval prolongation and ventricular fibrillation in childhood end-stage renal disease. | Ventricular arrhythmia is a major cause of death in end-stage renal disease (ESRD). Corrected QT (QTc) interval prolongation, which is one of the predictors of ventricular arrhythmia, may be associated with ESRD. We report an 11-year-old boy who had ESRD with marked QTc interval prolongation and developed torsade de po... |
8,418 | [Effects of defibrillation in the multiple-lead cardiac defibrillation systems on left ventricular function in animal model]. | This study evaluates the immediate effects of the endocardial electrical defibrillation delivered by two transvenous defibrillation systems on left ventricular (LV) function in the animal model. Automatic cardiac defibrillation systems with bipolar leads (group I) and tripolar leads (group II) were placed in the hearts... |
8,419 | Varicella zoster induced cardiac dysfunction: a case report. | A case is presented of cardiac arrhythmia associated with varicella zoster infection, affecting a 34-year-old man. The patient presented with episodes of seizure-like activity, which were subsequently shown to be caused by ventricular fibrillation. The literature regarding this unusual complication of varicella zoster ... |
8,420 | [Same genotype and different phenotypes in a family with PRKAG2 gene mutation]. | The gamma(2) subunit of AMP-activated protein kinase (PRKAG2) located in chromosome 7 plays an important role in regulating metabolic pathways, and patients with PRKAG2 mutations are associated with familial ventricular pre-excitation, hypertrophic cardiomyopathy and AV block. We observed the difference on the phenotyp... |
8,421 | [Transcoronary ablation of septal hypertrophy versus dual-chamber cardiac pacing for the treatment of aged patients with hypertrophic obstructive cardiomyopathy]. | To compare the safety and efficacy of transcoronary ablation of septal hypertrophy (TASH) versus dual-chamber cardiac pacing (PM) for the treatment of aged > 60 years old) patients with hypertrophic obstructive cardiomyopathy (HOCM).</AbstractText>Medically uncontrolled symptomatic aged patients with hypertrophic ob... |
8,422 | Novel electrode design for potentially painless internal defibrillation also allows for successful external defibrillation. | Implantable cardioverter defibrillators (ICDs) save lives, but the defibrillation shocks delivered by these devices produce substantial pain, presumably due to skeletal muscle activation. In this study, we tested an electrode system composed of epicardial panels designed to shield skeletal muscles from internal defibri... |
8,423 | Specific antivenom for Bungarus candidus. | Bungarus candidus (Malayan krait) snake is a neurotoxin snake. Previous treatment after snakebite was mainly respiratory support until the patient had spontaneous breathing. Recently specific antivenom for the Bungarus candidus snake was produced by the Queen Saovabha Memorial Institute and distributed in June 2004. Th... |
8,424 | Ventricular arrhythmias during Tako-tsubo syndrome. | Tako-tsubo syndrome is a recently described form of cardiomyopathy. Its pathophysiology remains unknown. However, the main demographic, clinical, electrocardiographic and biologic characteristics of the disease have been described by previous reports. Retrospective studies are essential to help describe this rare disea... |
8,425 | Rhythms of high-grade block in an ionic model of a strand of regionally ischemic ventricular muscle. | Electrical alternans, a beat-to-beat alternation in the electrocardiogram or electrogram, is frequently seen during the first few minutes of acute myocardial ischemia, and is often immediately followed by malignant cardiac arrhythmias such as ventricular tachycardia and ventricular fibrillation. As ischemia progresses,... |
8,426 | Antiarrhythmic effect of newly synthesized compound 44Bu on model of aconitine-induced arrhythmia -- compared to lidocaine. | The antiarrhythmic action of the newly developed compound 44Bu (an original compound that was synthesized at our Faculty of Pharmacy) was tested on a model of aconitine-induced arrhythmia and compared with the effect of lidocaine. Both tested substances were administered either as therapeutic or prophylactic agents. 44... |
8,427 | [Electrotherapy of cardiac failure]. | Intracardiac conduction disturbances, mostly manifested as a left bundle branch block (LBBB), are common findings in cardiac failure and associated with a poor prognosis. LBBB is a marker of disease progression and also leads to worsened cardiac hemodynamics by dyssynchronous contraction that can accelerate progression... |
8,428 | Role of maximum rate of depolarization in predicting action potential duration during ventricular fibrillation. | During ventricular fibrillation (VF) only 39% of the variation in action potential duration (APD) is accounted for by the previous diastolic interval [DI((n-1))], i.e., restitution, and the previous APD [APD((n-1))], i.e., memory. We tested the hypothesis that a characteristic of the AP upstroke, the maximum rate of de... |
8,429 | Spatial distribution of fibrosis governs fibrillation wave dynamics in the posterior left atrium during heart failure. | Heart failure (HF) commonly results in atrial fibrillation (AF) and fibrosis, but how the distribution of fibrosis impacts AF dynamics has not been studied. HF was induced in sheep by ventricular tachypacing (220 bpm, 6 to 7 weeks). Optical mapping (Di-4-ANEPPS, 300 frames/sec) of the posterior left atrial (PLA) endoca... |
8,430 | Valvular aortic stenosis in the elderly. | Elderly patients with valvular aortic stenosis have an increased prevalence of coronary risk factors, of coronary artery disease, and evidence of other atherosclerotic vascular diseases. Statins may reduce the progression of aortic stenosis (AS). Angina pectoris, syncope or near syncope, and congestive heart failure ar... |
8,431 | Activation patterns of Purkinje fibers during long-duration ventricular fibrillation in an isolated canine heart model. | The roles of Purkinje fibers (PFs) and focal wave fronts, if any, in the maintenance of ventricular fibrillation (VF) are unknown. If PFs are involved in VF maintenance, it should be possible to map wave fronts propagating from PFs into the working ventricular myocardium during VF. If wave fronts ever arise focally dur... |
8,432 | Comparison of N-terminal pro-brain natriuretic peptide versus electrophysiologic study for predicting future outcomes in patients with an implantable cardioverter defibrillator after myocardial infarction. | The aim of the study was to examine the predictive value of N-terminal pro-brain natriuretic peptide (NT-pro-BNP) versus electrophysiologic study in patients with implantable cardioverter-defibrillators (ICDs) after myocardial infarction (MI). We prospectively studied 99 consecutive patients with a history of MI who un... |
8,433 | Sternal fracture and osteomyelitis: an unusual complication of a precordial thump. | Out of hospital cardiac arrest is generally managed by cardiopulmonary resuscitation (CPR) and defibrillation. The precordial thump can also be used in the initial management of witnessed cardiac arrest whilst awaiting direct current cardioversion. However, complications are associated with a precordial thump. We repor... |
8,434 | Levosimendan improves the initial outcome of cardiopulmonary resuscitation in a swine model of cardiac arrest. | Cardiac arrest remains the leading cause of death in Western societies. Advanced Life Support guidelines propose epinephrine (adrenaline) for its treatment. The aim of this study was to assess whether a calcium sensitizer agent, such as levosimendan, administered in combination with epinephrine during cardiopulmonary r... |
8,435 | Torsades de pointes and self-terminating ventricular fibrillation in a prescription methadone user. | Methadone is known to prolong the QT interval and precipitate torsades de pointes. A 54-year-old prescription methadone user with hypokalaemia was referred to Critical Care with acute confusion and respiratory distress. Alcohol withdrawal was the presumed precipitant. The real precipitant only became evident on analysi... |
8,436 | Noninvasive ECG as a tool for predicting termination of paroxysmal atrial fibrillation. | Atrial fibrillation (AF) is the most common cardiac arrhythmia and entails an increased risk of thromboembolic events. Prediction of the termination of an AF episode, based on noninvasive techniques, can benefit patients, doctors and health systems. The method described in this paper is based on two-lead surface electr... |
8,437 | Reduced thyrotropin in euthyroid goitrous patients suggesting subclinical hyperthyroidism. | Subclinical hyperthyroidism, a biochemical finding of low serum thyrotropin (TSH) with the serum levels of thyroxine (T4) and triiodothyronine (T3) within the reference range, could easily be ignored by clinicians, as it, usually, does not manifest with any thyroid specific symptoms. It is of two types: endogenous and ... |
8,438 | What cardioversion protocol for ventricular fibrillation should be followed for patients who arrest shortly post-cardiac surgery? | A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was how many cardioversion attempts should be performed for patients who have gone into ventricular fibrillation post-cardiac surgery prior to performing chest reopening. Using the reported search, 1183 paper... |
8,439 | Out-of-hospital cardiac arrest caused by transient left ventricular apical ballooning syndrome. | We describe a case of out-of-hospital cardiac arrest due to ventricular fibrillation in a patient with transient left ventricular apical ballooning syndrome. Our report confirms that left ventricular apical ballooning may have the same complications of myocardial infarction, adding the early ventricular fibrillation to... |
8,440 | Bradycardia pacing-induced short-long-short sequences at the onset of ventricular tachyarrhythmias: a possible mechanism of proarrhythmia? | The purpose of this study was to characterize interactions between normal pacing system operation and the initiating sequence of ventricular tachycardia (VT)/ventricular fibrillation (VF).</AbstractText>Abrupt changes in ventricular cycle lengths (short-long-short, S-L-S) might initiate VT/VF. The S-L-S sequences might... |
8,441 | Surgical treatment of arrhythmias in adults with congenital heart defects. | Supraventricular and ventricular arrhythmias are a major cause of morbidity and mortality in adult patients with congenital heart disease (CHD). Intraoperative ablation offers an alternative to the complex surgical Cox-Maze procedure for these patients. We present the results of our preliminary experience with intraope... |
8,442 | Real-time monitoring of cardiac metabolism using biosensors shows myocardial protection during ischemia-reperfusion injury with glucose-insulin-potassium administration. | Systemic infusion of glucose-insulin-potassium (GIK) is thought to confer myocardial protection during ischemia-reperfusion injury. Our laboratory has experience with real-time monitoring of glucose and pH levels using needle-mounted biosensors. We tested the hypothesis that GIK enhances myocardial metabolism as displa... |
8,443 | [Epidemiology and new predictors of atrial fibrillation after coronary surgery]. | Postoperative atrial fibrillation (PAF) is a frequent complication of coronary artery bypass grafting (CABG). Our aims were to study its epidemiology and to identify predictors in everyday clinical practice, while taking into account statin use, extracorporeal circulation, and new biomarkers of inflammation and ventric... |
8,444 | [Risk stratification of asymptomatic subjects using resting ECG and stress ECG]. | The resting electrocardiogram (ECG) and stress ECG are established tests in the array of cardiovascular diagnostic modalities. In addition to their diagnostic value for structural heart disease and rhythm disorders, ECGs at rest or during stress also contain prognostically relevant information. Several ECG abnormalitie... |
8,445 | The effect of angiotensin receptor blockers for preventing atrial fibrillation. | Atrial fibrillation is the most common sustained cardiac arrhythmia in clinical practice, and causes significant burden to patients and health care systems. Clinicians treat existing atrial fibrillation with anticoagulation and/or drugs that utilize either a rate or rhythm control strategy. It remains unclear how best ... |
8,446 | [Takotsubo cardiomyopathy associated with torsades de pointes and long QT interval: a case report]. | A 77-year-old man was admitted to our hospital for pneumonia. On admission, electrocardiography showed ST segmental elevation and echocardiography showed abnormal movement of the left ventricular walls. Emergent coronary angiography was not performed because of his high C-reactive protein values and negative troponin T... |
8,447 | [Primary aldosteronism with ventricular fibrillation: a case report]. | A 60-year-old female had sudden onset of syncope. The emergency service noticed that she suffered cardiopulmonary arrest (ventricular fibrillation: VF). After defibrillation in the ambulance, she was transported to our emergency department. Electrocardiography monitoring showed QT prolongation. Serum potassium level wa... |
8,448 | [Assessment of pathophysiology based on the left ventricular shape in five patients with midventricular obstructive hypertrophic cardiomyopathy]. | The pathophysiology of midventricular obstructive hypertrophic cardiomyopathy (MVO) is unknown. Patients with MVO and MVO-like cardiomyopathy were classified into three groups based on the cardioimaging morphological characteristics of the left ventricle to investigate their complications and treatment.</AbstractText>F... |
8,449 | Digoxin and mortality in atrial fibrillation: a prospective cohort study. | The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study showed that rhythm-control treatment of patients with atrial fibrillation (AF) offered no survival advantage over a rate-control strategy. In a subgroup analysis of that study, it was found that digoxin increased the death rate [relativ... |
8,450 | Defibrillation testing of the implantable cardioverter defibrillator: when, how, and by whom? | The implantable cardioverter-defibrillator (ICD) has become an integral part of treatment for a variety of patients with symptomatic, or at risk for, ventricular tachyarrhythmias. The ICD's effectiveness is attributed to its ability to promptly detect and terminate ventricular tachycardia (VT) and fibrillation (VF). Th... |
8,451 | Evolution of left atrial systolic and diastolic functions in different stages of hypertension: distinct effects of blood pressure control. | To evaluate the left atrial (LA) volume, and LA systolic (contractile) and diastolic (expansion) functions in different stages of hypertension with or without atrial fibrillation (AF), as well as the effects of good blood pressure control.</AbstractText>A prospective observational study. Individuals including 22 normot... |
8,452 | Effects of protein kinase C activation on cardiac repolarization and arrhythmogenesis in Langendorff-perfused rabbit hearts. | Cardiac arrhythmias are still a major cause of mortality in western countries. Currently available antiarrhythmic drugs are limited by a low efficacy and proarrhythmic effects. The role of the protein kinase C (PKC) signalling pathway in arrhythmogenesis is still unclear. The goal of the present study was to test the e... |
8,453 | The BRIGHT study: bifocal right ventricular resynchronization therapy: a randomized study. | The BRIGHT study evaluated bifocal right ventricular (RV) (apex and outflow tract) pacing in a single, blind, randomized crossover study in patients eligible for cardiac resynchronization therapy (CRT). Forty-two patients were enrolled with the following characteristics: chronic drug refractory heart failure New York H... |
8,454 | [Cardioversion and atrial stunning]. | Stunned atrium is defined as a state of temporary mechanic atrial dysfunction with preserved bioeletrical function. It may follow up to 38-80% successful cardioversions performed to convert atrial fibrillation to regular sinus rhythm. Lack of effective atrial contractility leads to hemodynamic changes, which may result... |
8,455 | [Clinical variants of Churg-Strauss eosinophilic vasculitis]. | The purpose of the study was to analyze clinical variants of eosinophilic vasculitis (EV). The authors observed 12 EV patients (five men and seven women; mean age 43 +/- 5.7) during a ten-year period. Two of the patients died of ventricular fibrillation due to myocarditis and of mesenterial thrombosis. Clinical variant... |
8,456 | Ventricular fibrillation in late recovery after dobutamine stress echocardiography. | A 62-year-old man with multiple cardiac risk factors, including diabetes mellitus type II, treated hypertension, and hyperlipidemia, had a dobutamine stress echocardiogram performed as part of a preoperative evaluation. At peak stress the patient developed an apical regional wall motion abnormality. Approximately 12 mi... |
8,457 | Can atrial vagal denervation influence ventricular function in a failing heart? | Atrial fibrillation (AF) and congestive heart failure (CHF) often coexist (AF-CHF), and each adversely affects the other with respect to management and prognosis. Therapy with antiarrhythmic drugs to maintain sinus rhythm was disappointing. Ablation is more successful than antiarrhythmic drug therapy for the prevention... |
8,458 | Inflammatory biomarkers are not predictive of intermediate-term risk of ventricular tachyarrhythmias in stable CHF patients. | Elevated levels of inflammatory biomarkers and brain natriuretic peptide (BNP) are associated with increased mortality in patients with heart failure (HF).</AbstractText>: The aim of the current study was to assess the correlation between circulating biomarkers and ventricular tachyarrhythmias among patients with HF.</... |
8,459 | Prevention of ventricular fibrillation requires central beta-adrenoceptor blockade in rabbits. | To study whether and how a lipophilic and a hydrophilic beta-adrenoceptor antagonist affects ventricular fibrillation (VF) after coronary artery occlusion in a rabbit model with high sympathetic and low cardiac vagal activation.</AbstractText>Rabbits were treated for 3 weeks (series 1) or 2 hours (series 2) with metopr... |
8,460 | Novel mutation in the SCN5A gene associated with arrhythmic storm development during acute myocardial infarction. | Ventricular tachycardia (VT) and ventricular fibrillation (VF) complicating Brugada syndrome, a genetic disorder linked to SCN5A mutations, and VF complicating acute myocardial infarction (AMI) both have been linked to phase 2 reentry.</AbstractText>Given the mechanistic similarities in arrhythmogenesis, the purpose of... |
8,461 | Spatially discordant voltage alternans cause wavebreaks in ventricular fibrillation. | Ventricular fibrillation (VF) is characterized by complex ECG patterns emanating from multiple, short-lived, reentrant electrical waves. The incessant breakup and creation of new daughter waves (wavebreaks) perpetuate VF. Dispersion of refractoriness (static or dynamic) has been implicated as a mechanism underlying wav... |
8,462 | Atrial fibrillation is common after ablation of isolated atrial flutter during long-term follow-up. | Previous studies have shown that the incidence of atrial fibrillation after atrial flutter ablation is approximately 20% among patients presenting with typical atrial flutter and no history of fibrillation. However, studies involving this population have been small, with follow-up typically less than 2 years.</Abstract... |
8,463 | Prognostic significance of atrial fibrillation is a function of left ventricular ejection fraction. | Atrial fibrillation (AF) has been reported to be associated with decreased survival in population-based studies. Its prognostic importance in end-stage heart failure is not clear.</AbstractText>We investigated the prognostic implications of AF as function of left ventricular (LV) ejection fraction (EF) in 8,931 consecu... |
8,464 | Treatment of ventricular dysrhythmias and sudden cardiac death: a guideline-based approach for patients with chronic left ventricular dysfunction. | With the rise in the use of device therapy implants, we are better identifying appropriate chronic heart failure patients for primary implantable defibrillator therapy who are at risk of ventricular arrhythmia. As our knowledge expands, however, controversial issues emerge. Guidelines have been endorsed by the major in... |
8,465 | Optimal myocardial protection strategy for coronary artery bypass grafting without cardioplegia: prospective randomised trial. | Although hypothermia and ischaemic preconditioning (IP) are independently recognised mechanisms of cardioprotection, interactions between myocardial temperature and preconditioning have not been investigated. Therefore, this study explored the possibility of inducing IP during hypothermia and quantifying its effects at... |
8,466 | Brain natriuretic peptide elevation and the development of atrial fibrillation following coronary artery bypass surgery. | The study was designed to determine whether the development of atrial fibrillation is associated with post-operative left ventricular dysfunction and subsequent left atrial stretch. We recruited 133 patients with well preserved pre-operative left ventricular function undergoing bypass surgery. Brain natriuretic peptide... |
8,467 | Detection of atrial arrhythmia in superconducting quantum interference device magnetocardiography; preliminary result of a totally-noninvasive localization method for atrial current mapping. | Map-guided surgery is the goal for treatment of atrial fibrillation (AF), because it minimizes unnecessary incisions or procedures. We propose a totally-noninvasive and even non-contact method to detect atrial arrhythmia with a superconducting quantum interference device magnetocardiography (MCG) system, and report the... |
8,468 | Preoperative predictive factors for mortality in acute type A aortic dissection: an institutional report on 217 consecutives cases. | Surgical treatment of type A acute aortic dissection remains a challenge, especially in elderly patients or in patients with a critical preoperative status. We have retrospectively assessed our series over a 15-year period starting in 1990, including patients operated under cardiac massage for preoperative cardiac arre... |
8,469 | The safety and efficacy of ibutilide in children and in patients with congenital heart disease. | The safety and efficacy of ibutilide in the cardioversion of atrial flutter and atrial fibrillation in children and in patients with congenital heart disease (CHD) is unknown.</AbstractText>Data from 19 patients (age 6 months to 34 years, median 16 years) who received ibutilide for atrial flutter or atrial fibrillation... |
8,470 | Myocardial protection by erythropoietin during resuscitation from ventricular fibrillation. | Human recombinant erythropoietin (rhEPO) can protect the myocardium during ischemia and reperfusion. We investigated whether rhEPO could ameliorate previously identified functional myocardial abnormalities that develop during resuscitation from cardiac arrest, using a rat model of ventricular fibrillation (VF) and clos... |
8,471 | The effect of vernakalant (RSD1235), an investigational antiarrhythmic agent, on atrial electrophysiology in humans. | To determine the acute effects of vernakalant (RSD1235) on electrophysiologic (EP) properties in humans.</AbstractText>Vernakalant is an investigational mixed ion channel blocker that can terminate acute atrial fibrillation (AF) in humans at 2 to 5 mg/kg and may be more "atrial-selective" than available agents.</Abstra... |
8,472 | Effect of pacing the right ventricular mid-septum tract in patients with permanent atrial fibrillation and low ejection fraction. | Permanent right ventricular (RV) pacing leads have been traditionally implanted in the right ventricular apex (RVA). Nowadays, some deleterious effects of RVA pacing have been recognized. The aim of this study was to evaluate the effect of different sites of RV pacing in patients with permanent atrial fibrillation (AF)... |
8,473 | Prevalence of paroxysmal atrial fibrillation depending on the regression of left ventricular hypertrophy in arterial hypertension. | Arterial hypertension (HTN) represents one of the major causes of atrial fibrillation, a cardiac arrhythmia with high prevalence and comorbidity. The aim of this study was to investigate whether paroxysmal atrial fibrillation can be treated by the regression of left ventricular hypertrophy achieved by antihypertensive ... |
8,474 | Comparative study of methods for ventricular activity cancellation in atrial electrograms of atrial fibrillation. | Atrial fibrillation is a very common cardiovascular disease in clinical practice. One relevant issue to understand its pathophysiological mechanisms is the analysis and interpretation of atrial electrograms (AEG). To study these signals properly, ventricular activity has to be removed from the AEG. In this work, a new ... |
8,475 | Comparison of optical and electrical mapping of fibrillation. | Optical recordings with transmembrane potential (Vm)-sensitive fluorescent dye, or extracellular potential (Ve) recordings are used to map spatiotemporal patterns of cardiac excitation during ventricular fibrillation (VF). While the optical and electrical methods are accepted, there has not been a test of whether they ... |
8,476 | Regression of electrocardiographic left ventricular hypertrophy during antihypertensive therapy and reduction in sudden cardiac death: the LIFE Study. | Sudden cardiac death (SCD) occurs more often in patients with ECG left ventricular (LV) hypertrophy. However, whether LV hypertrophy regression is associated with a reduced risk of SCD remains unclear.</AbstractText>The Losartan Intervention for End Point Reduction in Hypertension (LIFE) study included 9193 patients 55... |
8,477 | Repolarization characteristics and incidence of Torsades de Pointes in patients with acquired complete atrioventricular block. | Torsades de pointes (TdP) during bradyarrhythmias have been reported to be associated with gender, degree of QT prolongation and duration of bradyarrhythmia. We sought to investigate the repolarization characteristics on 12-lead electrocardiogram (ECG) and the incidence of TdP in patients with acquired complete atriove... |
8,478 | Changes in ionic currents and reduced conduction velocity in hypertrophied ventricular myocardium of Xin alpha-deficient mice. | mXin alpha, a downstream target gene of Nkx2.5 transcription factor, was shown to encode a proline-rich and Xin repeats-containing protein which localizes to the intercalated disc of adult hearts. Our previous voltage-clamp studies have shown that the ventricular myocytes of mXin alpha -deficient mice exhibited a signi... |
8,479 | Clinical impact of surface electrocardiography of cardiac arrhythmias in pacemaker-ICD patients. | Cardiologists often are called to explain electrocardiograms of pacemaker/ implantable cardioverter (PMK/ICD) patients during arrhythmic events. The most frequent arrhythmia is atrial fibrillation (AF) whether in PMK or in ICD patients. Generally, it is not difficult to diagnose, it can affect the quality of life of th... |
8,480 | Magnetocardiography provides non-invasive three-dimensional electroanatomical imaging of cardiac electrophysiology. | More than two decades of research work have shown that magnetocardiographic mapping (MCG) is reliable for non-invasive three-dimensional electroanatomical imaging (3D-EAI) of arrhythmogenic substrates. Magnetocardiographic mapping is now become appealing to interventional electrophysiologists after recent evidence that... |
8,481 | Importance of body surface potential field representation fidelity: analysis of beat-to-beat repolarization measurements. | According to previous studies, the complex substrate of malignant arrhythmias needs a detailed spatio-temporal noninvasive characterization of low-amplitude dynamic changes in beat-to-beat cardiac repolarization.</AbstractText>Body surface potential map (BSPM) records were taken on 14 healthy male and female subjects (... |
8,482 | Enhanced heterogeneity of myocardial conduction and severe cardiac electrical instability in annexin A7-deficient mice. | Annexin A7 is involved in cardiomyocyte membrane organization and Ca(2+)-dependent signalling processes. We investigated the impact of annexin A7 on cardiac electrophysiological properties using an annexin A7-deficient mouse strain (annexin A7(-/-)).</AbstractText>Nineteen adult annexin A7(-/-) and 14 wild-type mice we... |
8,483 | Hemangioma located just above the left main coronary artery, in a subject who had cardiac arrest due to ventricular fibrillation, led to a diagnosis of Brugada syndrome. | We report the case of a 38-year-old Asian man with a pericardial hemangioma on the left main coronary artery. The patient presented initially at our hospital after cardiopulmonary resuscitation following an episode of ventricular fibrillation (VF). Because of spontaneous coved-type ST segment elevation on the higher in... |
8,484 | [Clinical characteristics of patients diagnosed of chronic heart failure attended in Primary Care. The CARDIOPRES study]. | Scarce information is available on the clinical characteristics and risk factors of patients with chronic heart failure (CHF) attended in Primary Care (PC) setting. The aim of this study was to analyze the clinical characteristics of this population in PC.</AbstractText>Multicenter, cross-sectional study in patients wi... |
8,485 | Circadian rhythms in cardiac arrhythmias and opportunities for their chronotherapy. | It is now well established that nearly all functions of the body, including those that influence the pharmacokinetics and pharmacodynamics of medications, exhibit significant 24-hour variation. The electrical properties of the heart as well as cardiac arrhythmias also vary as circadian rhythms, even though the suboptim... |
8,486 | Predictors of mortality after aortic valve replacement. | Aortic valve replacement (AVR) is recommended as a standard surgical procedure for aortic valve disease. Still the evidence for commonly claimed predictors of post-AVR prognosis, in particular mortality, appears scant. This systematic review reports on the evidence for predictors of post-AVR mortality, and may be helpf... |
8,487 | Increased prevalence of ventricular fibrillation in patients with type 2 diabetes mellitus. | Diabetes mellitus (DM) is an independent risk for cardiovascular disease. Furthermore, patients with DM have increased risk for ventricular arrhythmia that is thought to be secondary to coronary artery disease (CAD) or congestive heart failure (CHF). We hypothesized that DM may cause ventricular arrhythmias independent... |
8,488 | Comparative study of intravenous amiodarone and procainamide in the treatment of atrial fibrillation of recent onset. | The aim of the present study was to compare the safety and efficacy of amiodarone and procainamide in the acute cardiology setting.</AbstractText>The study population consisted of 223 patients with symptomatic atrial fibrillation (AF). After administration of digoxin for ventricular rate control, all patients who faile... |
8,489 | Endocardial electrograms from the right ventricular outflow tract after induced ventricular fibrillation in patients with Brugada syndrome. | The pathogenesis of Brugada syndrome (BS) is reported to be phase 2 reentry resulting from shortening of the action potential duration at the epicardial site of the right ventricular outflow tract (RVOT). However, several reports have shown a high incidence of ventricular late potentials (LPs) and a high rate of induct... |
8,490 | Endothelin receptor antagonist CPU0213 suppresses ventricular fibrillation in L-thyroxin induced cardiomyopathy. | Arrhythmias correlate with disorders of either K(2+) channels in sarcolemma or calcium modulating system in sarcoplasmic reticulum which handles Ca(2+) intracellularly. We hypothesized that an activated endothelin (ET) signaling pathway, which may be associated with an alteration of K(+) channels and Ca(2+) uptake acti... |
8,491 | Nandrolone potentiates arrhythmogenic effects of cardiac ischemia in the rat. | Anabolic steroid abuse has been associated with thrombosis and arteriosclerosis, both of which predispose to myocardial ischemia and infarction. However, there are reports of sudden cardiac death in the absence of thrombus and atheroma following anabolic steroid use. Although treatment with the commonly abused steroid,... |
8,492 | Implantable cardioverter-defibrillators and prevention of sudden cardiac death in hypertrophic cardiomyopathy. | Recently, the implantable cardioverter-defibrillator (ICD) has been promoted for prevention of sudden death in hypertrophic cardiomyopathy (HCM). However, the effectiveness and appropriate selection of patients for this therapy is incompletely resolved.</AbstractText>To study the relationship between clinical risk prof... |
8,493 | [Surgical ablation therapy - lessons learned]. | Atrial fibrillation (AF) is the most frequent sustained arrhythmia affecting more than 5% of the population above 65 years resulting in loss in quality of life and life expectancy. Since the introduction of the MAZE procedure, an increasing number of surgical approaches have been implemented for the treatment of AF. Du... |
8,494 | Surgical treatment of atrial fibrillation : a systematic review. | The recently published overwhelming number of publications on the surgical treatment of AF, using a wide variety of techniques, blurred any precise appreciation of the nowadays surgical treatment of AF. As a consequence, the "state of the art" of the surgical technique of AF is ill-defined.</AbstractText>In this review... |
8,495 | [History of rhythm surgery with focus on surgical ablation procedures to treate atrial fibrillation]. | Rhythm surgery, which was initiated many years ago, has fundamentally changed by the development of sparing interventional treatment procedures and the successful introduction of the implantable defibrillator.A cornerstone in the history was the first successful treatment of a patient with Wolff-Parkinson-White-Syndrom... |
8,496 | [Endovascular treatment of coronary arterial fistulae in children and adults]. | The authors report their experience of endovascular treatment of coronary fistulae in 25 patients aged 2 to 77 years (median 29 years) who underwent 30 interventional catheterisation procedures. The origin of the fistulae was variable: left coronary (14 cases), right coronary (6 cases) and bilateral (5 cases) as were t... |
8,497 | Clinical trials update from Heart Rhythm 2007 and Heart Failure 2007: CARISMA, PREPARE, DAVID II, SAVE-PACE, PROTECT and AREA-IN-CHF. | This article provides information and a commentary on trials relevant to the pathophysiology, prevention and treatment of heart failure, presented at Heart Rhythm 2007 organised by the Heart Rhythm Society which was held in Denver, USA and Heart Failure 2007 organised by the Heart Failure Association of the European So... |
8,498 | Rescue shock outcomes during out-of-hospital cardiac arrest. | Questions remain about the optimal timing and method for treating ventricular fibrillation (VF) during out-of-hospital cardiac arrest, and a variety of treatment protocols are used. Detailed description of rescue shock outcomes during actual patient care under different protocols would allow rational comparison of trea... |
8,499 | Myocardial performance index following electrically induced or ischemically induced cardiac arrest. | We sought to investigate the echocardiographic myocardial performance index (MPI) to assess post-resuscitation myocardial function following electrically and ischemically induced ventricular fibrillation (VF).</AbstractText>VF was induced in fourteen anesthetized pigs weighing 38+/-4 kg. VF was induced electrically in ... |
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