PMID int64 35.7M 36.4M | Title/Abstract stringlengths 22 8.78k | MeshTerms stringlengths 7 101 | SemanticTypes stringlengths 4 64 |
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36,293,406 | chemiluminesc combin organ photosensit beyond light penetr depth limit photodynam therapi photodynam therapi pdt promis noninvas medic technolog approv treatment varieti diseas includ bacteri fungal infect skin diseas sever type cancer recent decad mani photosensit develop appli pdt howev pdt still limit light penetr d... | D010778;D009369 | T061;T191 |
36,293,405 | develop method produc oxldl character effect hpv posit head neck cancer cell cardiovascular diseas cvd cancer two main caus death worldwid initi progress atherosclerosi larg part caus oxid low densiti lipoprotein oxldl interest oxldl may also play role cancer cell metabol migrat oxldl general obtain tedious ultracentri... | D030361;D006258 | T047;T191 |
36,293,404 | advanc genet studi powderi mildew resist tgr cucurbit powderi mildew cpm one main limit factor melon cultiv worldwid resist race report african access tgr whose resist control domin recess epistasi domin recess quantit trail loci qtl previous locat chromosom respect use sever dens genotyp bc famili deriv cross tgr susc... | D001203 | T004 |
36,293,403 | human papillomavirus e apoptosi induc protein cancer treatment systemat review human papillomavirus type hpv well known etiolog factor cervic oropharyng cancer e protein product earli transcrib gene hpv postul caus death cancer cell via p depend p independ pathway main aim present systemat review studi hpv e protein ap... | D009856;D030361;D009959;D002583 | T123;T047;T191;T116 |
36,293,402 | transcriptom metabolom analysi color chang fruit develop pepper capsicum baccatum fruit color one critic characterist pepper studi pepper capsicum baccatum l fruit four tran color period use experiment materi explor color convers mechan pepper fruit transcriptom metabolom analysi identifi total flavonoid metabolit caro... | D002212 | T168;T002 |
36,293,401 | singl cell transcriptom wet amd patient deriv endotheli cell angiogen sprout age relat macular degener amd global lead caus visual impair older popul wet amd common subtyp diseas occur patholog angiogenesi infiltr subretin space choroid neovascular caus hemorrhag retin damag gold standard anti vascular endotheli growth... | D020256;D057135 | T047;T046 |
36,293,400 | zearalenon induc mechan damag intestin barrier via rhoarock signal pathway ipec j cell zearalenon zen widespread contamin cereal agricultur product caus food safeti issu ingest food feed contamin zen disrupt intestin epitheli barrier function rhoarock signal pathway play key role regul epitheli barrier function studi r... | D009219;D015025 | T131;T126;T116;T109 |
36,293,399 | platelet deriv exosom atherosclerosi atherosclerosi main caus mani cardiovascular diseas cvds progress inflammatori diseas character accumul lipid fibrous element calcif innermost layer arteri result thicken clog vessel wall sever cell type direct involv patholog progress among platelet repres link inflamm thrombosi in... | D055354;D055252;D050197;D013927 | T026;T047;T046 |
36,293,398 | individu variabl adipos stem cell prolifer gene express respons lipopolysaccharid stimul adipos stem cell asc report play role normal physiolog well inflamm diseas object work elucid inter individu differ growth gene express respons inflammatori stimuli asc differ donor human asc male donor asc femal donor purchas lonz... | D008070;D016178 | T129;T116;T109 |
36,293,397 | kidney cyst line epitheli cell resist low dose cisplatin induc dna damag preclin model autosom domin polycyst kidney diseas increas dna damag respons ddr signal kidney cyst line epitheli cell cec may provid opportun cell specif therapeut target autosom domin polycyst kidney diseas adpkd hypothes inhibit ataxia telangie... | D016891;D003560 | T019;T047;T190 |
36,293,396 | role tunnel nanotub nervous system cellular communic transfer inform one cell anoth crucial cell viabil homeostasi last decad tunnel nanotub tnts attract scientif attent mean direct intercellular communic also possibl system transport biolog cargo distant cell peculiar tnt characterist make abl increas cellular surviv ... | D019636;D043942 | T047;T073 |
36,293,395 | potenti antifung target aspergillus sp calcineurin heat shock protein pathway aspergillus speci especi fumigatus lesser extent other flavus niger terreus although rare pathogen healthi human aggress immunocompromis patient opportunist pathogen although surviv rate infect improv recent decad follow introduct azol deriv ... | D005659;D009701 | T131;T126;T116 |
36,293,394 | gpi anchor protein thi cd promot wound heal upon injuri skin enhanc skin perfus wound heal high regul multi step process involv plethora signal blood perfus crucial wound heal abnorm format new blood vessel defin outcom wound heal process thi implic angiogenesi silenc thi gene retard wound heal process howev role thi b... | D012867;D014945 | T022;T040 |
36,293,393 | physiolog transcriptom analys reveal effect elev root zone co metabol sugar starch root orient melon seedl root zone co major factor affect crop growth develop nutrient uptak metabol orient melon affect root zone gase growth microstructur sugar starch content enzymat activ relat sugar starch metabol gene express root o... | D036226;D028463 | T168;T002 |
36,293,392 | blood reflux induc epigenet factor hdac dnmts associ develop human chronic venous diseas blood reflux metabol regul play import role chronic venous diseas cvd develop histon deacetylas hdac dna methyltransferas dnmts serv repressor inhibit metabol signal induc proatherogen flow promot aortic endotheli cell ec dysfunct ... | D006655;D014648 | T026;T047;T126;T116 |
36,293,391 | ration mutagenesi lid domain ribokinas e coli result order magnitud increas activ toward arabinos develop effici approach product medic import nucleosid high relev challeng biotechnolog particular cascad synthesi arabinosid would allow relat easi product various cytostat antivir drug howev biocatalyst necessari approac... | D001089;D054697 | T121;T109 |
36,293,390 | gut microbiota metabol disord breast cancer could berberin turn transvers nutraceut tool narrat analysi metabol disord main character mark alter lipid carbohydr profil addit clinic presenc direct consequ alter patholog condit consider increas preval recent year direct link onset various patholog includ cancer particula... | D000069196;D001599;D001943;D008659 | T121;T007;T109;T191;T047;T001 |
36,293,389 | isol peptid inhibit sgc cell prolifer aspongopus chinensi dalla aspongopus chinensi dalla use tradit chines medicin well edibl insect although anti tumor effect observ anti tumor activ compon hemolymph chinensi remain unknown studi combin usag ultrafiltr gel filtrat chromatographi fplc rp hplc separ purifi activ peptid... | D013274;D020062;D013111 | T123;T116;T131;T191;T204 |
36,293,388 | lipid droplet lung cancer crucial cell growth starvat surviv rapid unlimit cell growth prolifer cancer cell requir larg quantiti nutrient mani metabol pathway nutrient uptak system frequent reprogram upregul meet demand cancer cell includ demand lipid lipid adult normal cell main acquir circulatori system whether diffe... | D013217;D008175 | T033;T191 |
36,293,387 | sox promot invas human bladder cancer mmp upregul foxo downregul sox member sri relat hmg box sox famili abnorm express mani tumor associ cancer stem cell like properti previous report shown sox biomark cancer stem cell human bladder cancer bc recent studi indic inhibit sox anticanc compound chla f attenu human bc cell... | D001749;D035683 | T123;T191;T114 |
36,293,386 | antimicrobi photoantimicrobi activ chitosancnppv nanocomposit multidrug resist bacteria repres global health econom burden urgent call new technolog combat bacteri antimicrobi resist develop novel nanocomposit ncps base chitosan display differ degre acetyl das conjug polym cyano substitut poli p phenylen vinylen cnppv ... | D048271;D053761 | T121;T073;T109 |
36,293,385 | use diamagnet coeffici estim reduc effect mass layer perovskit new insight high magnet field spectroscopi work current state research concern determin effect mass layer perovskit present avail experiment report reduc effect mass direct measur use magneto absorpt spectroscopi interband landau level review compar result ... | D060526 | T070 |
36,293,384 | impact placent slca defici first half gestat rumin placenta glucos uptak transfer mediat facilit glucos transport slca glut slca glut slca locat basolater trophoblast membran wherea slca locat sole matern face apic trophoblast membran slca less abund slca slca five fold greater affin transport capac base locat slca lik... | D007003;D061385 | T121;T047 |
36,293,383 | deodor garlic decreas oxid stress caus lipopolysaccharid rat heart hydrogen sulfid preliminari find deodor garlic dg may favor activ antioxid enzym promot synthesi hydrogen sulfid h object test dg favor increas h decreas oxid stress caus lipopolysaccharid lps rat heart total rat divid group group control c group lps gr... | D006862;D005737;D012643 | T123;T121;T131;T197;T168;T196;T130 |
36,293,382 | mnhr function molt macrobrachium nipponens regul e synthesi mediat e signal hr member nuclear receptor famili extens studi insect molt develop report crustacean still lack current studi mnhr gene identifi macrobrachium nipponens improv molt molecular mechan nipponens studi investig whether mnhr function molt process ni... | D018978;D033541 | T040;T204 |
36,293,381 | antifung effect nanoparticl covid link black fungus perspect biomed applic sever acut respiratori syndrom coronavirus sar cov high transmiss pathogen coronavirus caus coronavirus diseas covid pandem multipl wave threaten human health public safeti pandem patient covid acquir secondari infect mucormycosi also known blac... | D000086382;D009091;D015034;D009090;D053758 | T121;T073;T067;T197;T004;T047 |
36,293,380 | deubiquitin enzym usp interact retin degener associ protein unca arl protein relat ubiquitin proteasom system play import role differenti ciliogenesi photoreceptor cell mutat sever gene involv ubiquitin proteostasi identifi causat inherit retin dystrophi ird ciliopathi usp deubiquitin enzym whose role retina still unex... | D046988;D058499 | T047;T126;T116 |
36,293,379 | advanc manag central nervous system metastas breast cancer central nervous system cns metastas common breast cancer bc patient particular relev new treatment bc prolong surviv review advanc treatment cns metastas bc includ radiotherapi system therapi evolv role immunotherapi use radiotherapi chemotherapi cornerston tre... | D001943;D016543;D016609;D018796;D001932 | T121;T129;T191 |
36,293,378 | reactiv centr loop mutagenesi serpinb target tmprss furin inhibit sar cov cell entri replic sar cov virus util host cell proteas facilit cell entri wherebi spike protein cleav two specif site enabl membran fusion furin transmembran proteas serin tmprss cathepsin l catl major proteas implic thus target anti viral therap... | D015843;D000086382 | T123;T121;T116;T067;T047 |
36,293,377 | global proteom profil aluminum induc hippocamp impair rat low dose aluminum realli safe hippocampus brain area aluminum al accumul abund wide associ learn memori present studi evalu behavior tissu proteom chang hippocampus wistar rat caus exposur dose mimic human consumpt aluminum chlorid alcl urban area male wistar ra... | D000535;D040901 | T121;T196;T091 |
36,293,376 | annexin improv osteogen differenti mesenchym stem cell expos high glucos condit lessen senesc osteoporosi frequent found chronic diabet patient result increas risk bone fractur occur under mechan osteoporosi diabet patient still larg unknown annexin anxa famili calcium bind protein report involv mani biolog process inc... | D017306;D059630;D010024 | T123;T047;T116;T025 |
36,293,375 | identif investig genet variat candid gene respons seed weight via gwas paper mulberri seed direct determin surviv popul size woodi plant genet basi seed weight woodi plant remain poor explor identifi genet variat candid gene respons seed weight natur woodi popul investig hundr seed weight paper mulberri individu differ... | D031625;D044783 | T116;T002 |
36,293,374 | assess evalu scope constraint idylla molecular assay use differ sourc materi routin diagnost set cancer treatment diagnost concern tumor type determin molecular marker short tat critic fulli autom real time pcr base molecular diagnost idylla assay well establish mani laboratori qualit detect short tat routin screen cli... | D009369 | T191 |
36,293,373 | eraphla c kir genet profil coupl recurr implant failur proper embryo implant depend toler matern immun system fetus foreign patern antigen implant earli pregnanc domin leukocyt uterus uterin nk cell express killer immunoglobulin like receptor kir kir recogn human leukocyt antigen hla c human trophoblast inherit father ... | D015236;D000076610 | T129;T034;T116 |
36,293,372 | thyroid hormon receptor knockdown reduc suppress progestin activ mtor pathway endometri cancer cell progestin resist major obstacl conserv therapi patient endometri cancer ec endometri atyp hyperplasia eah howev relat induc factor yet unclear studi thyroid hormon receptor tr tr patient assay thrb silenc rl kle ec cell ... | D011372;D016889 | T125;T121;T039;T191 |
36,293,371 | mulberri compon kuwanon c exert potent therapeut efficaci vitro covid block sar cov spike rbd ace receptor interact immens effort global pharmaceut compani develop anti covid drug includ small molecul base rna replic inhibitor via drug reposit antibodi base spike protein blocker relat cell entri sar cov howev sever lim... | D000086382;D031625;D001688 | T121;T123;T067;T047;T002 |
36,293,370 | updat innat immun acut kidney injuri lesson taken covid serious clinic cours sar cov infect usual accompani acut kidney injuri aki worsen prognosi increas mortal aki covid consequ system dysregul lead inflamm thrombosi vascular endotheli damag necrosi process reli interact innat immun element includ circul blood cell r... | D000086382;D058186 | T047;T037;T067 |
36,293,369 | characterist exosom vascular landscap regul exosom sequestr peripher tissu brain exosom mediat intercellular communic shuttl messag cell tissu explor whether exosom tissu sequestr determin exosom tissu use ten radiolabel exosom human murin cancer noncancer cell line measur sequestr exosom liver kidney spleen lung intra... | D055354 | T026 |
36,293,368 | boadhbna effici uv maldi matrix high sensit auto tag glycom matrix select critic factor success glycom studi use matrix assist laser desorptionion mass spectrometri maldi ms studi evalu optim new solid ionic matrix benzylhydroxylamin boa dihydroxybenzo acid dhb na contain boa small amount sodium counter salt dhb concen... | D054794;D011134 | T090;T121;T109 |
36,293,367 | revers platelet integrin iib activ thrombus instabl integrin iib activ essenti platelet aggreg accord hemostasi arteri thrombosi iib integrin high express platelet requir activ step bind fibrinogen fibrin von willebrand factor vwf current model assum process integrin activ reli actomyosin forc depend molecular chang be... | D019039;D013927 | T129;T046;T116;T192 |
36,293,366 | landscap genom alter pd l express earli stage non small cell lung cancer nsclc singl center retrospect observ studi precis oncolog immunotherapi revolution treatment advanc non small cell lung cancer nsclc emerg studi show target therapi also benefici patient driver alter epiderm growth factor receptor egfr mutat earli... | D002289;D008175;D055752 | T191 |
36,293,365 | betula alba bark extract empetrum nigrum fruit juic natur altern niacinamid skin barrier benefit scandinavian region home uniqu biom endem plant speci aim studi explor natur divers identifi plant extract provid posit skin barrier effect six plant extract identifi start materi follow biochem screen two candid outperform... | D029791;D024301 | T002 |
36,293,364 | methyl chh context allow predict recombin rice dna methyl studi epigenet trait consid key factor regul plant develop physiolog associ regul sever genom featur includ transposon silenc regul gene express recombin rate nonetheless understand relat dna methyl recombin rate remain challeng work explor associ recombin rate ... | D012275 | T168;T002 |
36,293,363 | role notch signal pathway recoveri cardiac function myocardi infarct myocardi infarct mi patholog process evidenc massiv death cardiomyocyt associ hypox oxid stress format area fibrosi ultim lead heart failur mechan contribut function repair heart mammal includ human notch signal pathway cardioprotect effect involv for... | D009203 | T047 |
36,293,362 | molecular dissect tdp lead caus alsftld tar dna bind protein tdp dnarna bind protein involv pivot cellular function especi rna metabol hyperphosphoryl ubiquitin tdp posit neuron cytoplasm inclus identifi brain spinal cord case amyotroph later sclerosi al substanti proport frontotempor lobar degener ftld case tdp dysfun... | D057174;D000690;D057180;D011328 | T047;T005;T116;T048 |
36,293,361 | genet basi increas preval metabol syndrom among post traumat stress disord patient post traumat stress disord ptsd high debilit psychiatr disord trigger exposur extrem trauma even ptsd primarili psychiatr condit also character advers somat comorbid one ill common co occur ptsd metabol syndrom met defin set health riskr... | D013313;D024821 | T047;T048 |
36,293,360 | differ rna element control viral protein synthesi polerovirus isol evolv separ geograph region plant virus lack cap poli structur common host mrnas crucial translat initi thus altern translat initi mechan identifi viral mrnas one control rna element end abl enhanc mrna cap independ translat cite cite modular transfer r... | D052679 | T005 |
36,293,359 | assess salt stress arabidopsi base detect hydrogen peroxid releas leav use electrochem sensor salt stress serious inhibitori effect various metabol process plant cell lead excess accumul reactiv oxygen speci ros hydrogen peroxid h type ros sever damag plant cell larg amount exist method assess content h releas leav sal... | D017360;D037742 | T104;T073;T002 |
36,293,358 | target cxcr cd receptor overview new old molecul biolog person anticanc therapi biolog therapi multifacet applic revolution treatment tumor main due abil exclus target cancer cell reduc advers effect normal tissu review focus therapi target cxcr cd receptor survey result earli clinic trial test compound classifi nonpep... | D051928;D009369 | T129;T191;T116 |
36,293,357 | third extracellular loop mammalian odor receptor involv ligand bind mammal recogn chemic air via g protein coupl odor receptor or addit orthoster bind site segment receptor modul ligand recognit focus human hora consid prototyp class ii or use combin molecular model site direct mutagenesi vitro function assay show thir... | D018035 | T116;T192 |
36,293,356 | manufactur xeno feeder free clinic grade human embryon stem cell line first step cell therapi human embryon stem cell hesc increas use clinic trial chang outcom treatment mani human diseas use start materi differenti specif cell type achiev desir result cell therapi thus qualiti hesc taken account therefor current good... | D000066449 | T025 |
36,293,355 | applic ftir spectroscopi detect chang skelet muscl composit due obes insulin resist stz induc diabet age obes diabet mellitus pathophysiolog interconnect factor signific contribut global burden non communic diseas metabol condit associ impair insulin function disrupt metabol carbohydr lipid protein lead structur functi... | D007333;D003921 | T046;T050 |
36,293,354 | transgener toler salt osmot stress induc plant virus infect follow pathogen infect plant develop divers mechan direct immun system toward robust induct defens respons recurr environment stress induc resist could inherit progeni render toler stress event although within generat induct toler abiot stress well document ph... | D017801;D017863 | T005 |
36,293,353 | genom wide associ express analysi lipoxygenas gene famili passiflora eduli reveal pelox might involv fruit ripe ester format aroma import factor fruit qualiti passiflora eduli passion fruit popular among consum rich flavor nutrit valu ester main compon volatil aroma passion fruit lipoxygenas lox first key enzym upstrea... | D029598 | T121;T168;T002;T109 |
36,293,352 | intact type interferon receptor signal prevent hepatocellular necrosi enceph dose depend manner rift valley fever virus infect mice rift valley fever rvf zoonot emerg diseas caus rvf virus rvfv rumin lead abort storm enhanc mortal rate young anim wherea human caus symptom like sever hemorrhag fever enceph role innat ad... | D012296;D006528;D008113;D004660;D007370 | T121;T129;T116;T191;T005;T047 |
36,293,351 | molecular mechan divers auxin respons plant growth develop plant hormon auxin act signal molecul regul numer development process throughout stage plant growth understand auxin regul various physiolog development process hot topic intrigu field recent studi unveil molecular detail divers auxin respons function everi asp... | D007210;D010937 | T125;T123;T116;T109 |
36,293,350 | molecular mechan mous uterin smooth muscl regul embryo implant myometrium play critic role multipl process embryo space peristalsi mous implant indic vital role smooth muscl success establish qualiti implant actin key element cytoskeleton structur play import role movement contract smooth muscl cell smcs howev function... | D000199;D011980 | T123;T116;T192 |
36,293,349 | isomir eqtl cancer specif express quantit trait loci databas mirna isoform identif express quantit trait loci eqtl import compon effort understand genet variant influenc diseas risk microrna mirna short noncod rna molecul capabl regul express sever gene simultan recent sever novel isom mirna isomir differ slight length... | D035683;D009369 | T123;T191;T114 |
36,293,348 | mayo clinic florida microdosimetr kinet model clonogen surviv applic various repair compet rodent human cell line relat biolog effect rbe calcul use plan ion therapi treatment general base microdosimetr kinet model mkm local effect model lem mayo clinic florida mkm mcf mkm recent develop overcom limit previous mkms rep... | D012377 | T015 |
36,293,347 | electr stimul human adipos deriv mesenchym stem cell plasma treat ito glass promot osteogen differenti electr signal repres essenti form cellular communic decad electr stimul use effect clinic practic enhanc bone heal howev detail mechan electr stimul bone heal well understood addit mani difficulti set stabl effici ele... | D010012;D059630 | T025;T042 |
36,293,346 | respons urotheli carcinoma cell line cisplatin cisplatin cddp base chemotherapi standard care patient muscl invas bladder cancer howev larg number case diseas becom resist respond cddp thus progress dissemin case prognosi patient poor cddp manifest cytotox effect main dna damag induct henc respons cddp main depend dna ... | D002295;D001749;D000970 | T121;T191;T109 |
36,293,345 | accuraci fib detect elev liver stiff measur patient non alcohol fatti liver diseas cross section studi referr center identif advanc fibrosi appli noninvas test still key compon diagnost algorithm nafld aim studi assess concord fib liver stiff measur lsm patient refer two liver center ultrasound base diagnosi nafld fibr... | D065626 | T047 |
36,293,344 | tryptophan modulatori role european seabass dicentrarchus labrax immun respons acut inflamm stress condit present work aim studi role dietari tryptophan supplement modul european seabass dicentrarchus labrax immun condit stress rear condit ie day exposur high densiti well immun respons acut inflamm intraperiton inject ... | D001492 | T013 |
36,293,343 | import fawrki strawberri fragaria ananassa fruit ripen wrki transcript factor play nonneglig role plant growth develop littl known involv wrki transcript factor regul fruit ripen studi fawrki identifi close relat fruit matur octoploid strawberri fawrki protein local nucleus respond cold salt low phosphat aba light qual... | D031985 | T168;T002 |
36,293,342 | earli doxorubicin myocardi injuri inflammatori oxid stress apoptot role galectin doxorubicin doxo effect drug use treatment larg number cancer regardless import chemotherapeut characterist usag restrict serious side effect obvious cardiotox manifest acut year complet treatment lead left ventricular dysfunct dilat cardi... | D037502;D006333 | T129;T047;T046;T116 |
36,293,341 | aphid bcr structur activ uncov new defensin peptid superfamili aphid hemiptera aphidoidea among detriment insect agricultur plant manag great challeng agronom research new class protein call bacteriocyt specif cystein rich bcr peptid provid altern chemic insecticid pest control bcrs initi identifi pea aphid acyrthosiph... | D001042;D007306 | T131;T204 |
36,293,340 | role cryoprotect agent liposom stabil preserv improv liposom usag drug deliveri vehicl cryoprotect util prevent constitu leakag liposom instabl cryoprotect agent cpas cryoprotect protect liposom mechan stress ice vitrifi specif temperatur form glassi matrix major studi cryoprotect demonstr concentr cryoprotect increas ... | D003451;D008081 | T121;T039;T109 |
36,293,339 | insight carbapenem resist vibrio speci current status futur perspect increas preval resist carbapenem escal concern carbapenem reserv last line antibiot although indiscrimin antibiot usag consid primari caus resist develop increas evid reveal inconsequenti strain without direct clinic relev carbapenem usag harbor carba... | D001618;D014733 | T007;T126;T116 |
36,293,338 | citrus flavonoid nobiletin downregul angiopoietin like protein angptl express exhibit lipid modul effect hepat cell adult zebrafish model nobiletin dietari citrus flavonoid exert biolog activ hyperlipidemia obes atherosclerot cardiovascular diseas ascvd aim studi explor lipid lower effect nobiletin under molecular mech... | D000091303;D002957 | T123;T168;T116;T002 |
36,293,337 | long term advers effect liver stiff glycaem control type diabet patient nonalcohol fatti liver diseas pilot studi current limit data regard long term effect liver stiff glycaem control patient type diabet mellitus tdm nonalcohol fatti liver diseas nafld prospect follow outpati sampl consecut postmenopaus women tdm nafl... | D065626;D003924 | T047 |
36,293,336 | rapid remov toxic remazol brilliant blue r dye aqueous solut use juglan nigra shell biomass activ carbon potenti adsorb optim isotherm kinet thermodynam investig recent treatment effluent agricultur wast biomass signific attract wide interest among research due avail efficaci low cost remov toxic remazol brilliant blue... | D031324;D014874 | T131;T002 |
36,293,335 | molecular genet event determin soften fleshi fruit comprehens review fruit soften occur fruit ripen postharvest storag determin fruit qualiti shelf life commerci valu make fruit attract seed dispers addit soften result fruit eventu decay render fruit suscept invas opportunist pathogen mani studi conduct reveal fruit so... | D005638;D010937 | T125;T168;T116;T002 |
36,293,334 | pyramid gna gs ipa exhibit complementari addit effect rice yield pyramid quantit trait loci qtls power approach breed super high yield varieti howev perform qtls improv rice yield vari specif genet background previous studi employ crisprca system target three yield relat gene gna gs ipa japonica zhonghua mutant featur ... | D012275 | T168;T002 |
36,293,333 | microb deriv antioxid reduc lipopolysaccharid induc inflammatori respons activ nrf pathway inhibit rosnlrpil signal pathway inflamm play import role innat immun respons yet overproduct inflamm lead varieti chronic diseas associ innat immun system therefor modul excess inflammatori respons consid major strategi treatmen... | D051267;D000071199 | T123;T116 |
36,293,332 | antithrombin therapeut intervent sepsi induc coagulopathi dissemin intravascular coagul lesson learn covid associ coagulopathi recent research contribut signific understand pathogenesi acut dissemin intravascular coagul covid consid new under condit dissemin intravascular coagul narrat review current evid present regar... | D004211;D000086382;D001778;D018805 | T047;T046;T067 |
36,293,331 | sensit cutan cell lymphoma cell mcl inhibitor correl lack bcl w express long term curat treatment cutan cell lymphoma ctcl remain major challeng therapi resist often base apoptosi defici may depend antiapoptot bcl protein bcl bcl x l bcl w mcl target sever antagonist generat mimic bcl homolog domain bh mimet dysregul o... | D000970;D016410 | T121;T191;T109 |
36,293,330 | chitosan hydroxycinnam acid conjug emerg biomateri rise applic biomedicin past thirti year research shown huge potenti chitosan biomed applic drug deliveri tissu engin regener cancer therapi antimicrobi treatment among other one major advantag interest polysaccharid modifi facilit use tailor made applic way molecular s... | D048271;D000890 | T121;T109 |
36,293,329 | tspo pet imag potent non invas biomark diffus intrins pontin glioma patient deriv orthotop rat model diffus intrins pontin glioma dipg first caus cerebr pediatr cancer death great benefit specif non invas biomark patient follow monitor drug efficaci sinc biopsi challeng brain tumor molecular imag may techniqu choic tar... | D005910;D000080443;D020295;D001254 | T191 |
36,293,328 | extracellular vesicl isol malign mesothelioma cancer associ fibroblast induc pro oncogen chang healthi mesotheli cell malign mesothelioma aggress tumour pleura mpm peritoneum clinic present advanc stage diseas current therapi margin improv surviv urgent need identifi new treatment carcinoma associ fibroblast caf repres... | D000086002;D000072645;D008654;D000067128 | T026;T191;T025 |
36,293,327 | quantit nmr base lipoprotein analysi identifi elev hdl triglycerid serum alzheim diseas patient alzheim diseas ad common form dementia elder associ chang lipoprotein metabol perform quantit lipoprotein analysi local cohort cognit impair elder control subject use standard nuclear magnet reson nmr spectroscopi commerci a... | D000544 | T047;T048 |
36,293,326 | mtor potenti target treatment microbi infect inflammatori bowel diseas colorect cancer mammalian target rapamycin mtor major control number import cellular activ includ protein synthesi cell expans multipl autophagi lysosom function cellular metabol mtor interact specif adaptor protein form two complex mtor complex mto... | D015212;D015179 | T047;T191 |
36,293,325 | treatment liquid smoke certain chemic constitu preval smoke reduc phloem vascular sectori sunflow improv growth mani higher plant possess physiolog organ base upon carbon economi part photosynth partit accord relat strength plant sink tissu mani speci also close relationship partit phyllotaxi vascular connect give rise... | D052585;D006368 | T002 |
36,293,324 | mother fetus immun cross talk coordin extrins intrins embryo gene express nois growth stabil development instabl di thought invers relat capac organ buffer develop random genet environment perturb di repres trait inter intra individu variabl inter individu variabl invers refer canal indic capabl organ reproduc trait in... | D009035;D016228 | T092;T099;T116;T123 |
36,293,323 | rhfgf protect epiderm cell uvb induc apoptosi activ ampk mediat autophagi ultraviolet irradi especi ultraviolet b uvb irradi increas risk various skin diseas sunburn photo age cancer howev drug avail treat skin lesion therefor discoveri drug improv health irradi skin urgent need fibroblast growth factor fgf metabol fac... | D055372;D001343 | T126;T116;T043 |
36,293,322 | assess dna damag effect ioniz radiat use plasmid dna plasmid dna use investig dna damag effect ioniz radiat studi explor feasibl plasmid dna base detector assess dna damag effect two radiotherapi x ray beam qualiti undergo return shipment km two institut detector consist amp nbsp l pbr dna enclos aluminum seal nine cyl... | D000535;D004249 | T121;T196;T049 |
36,293,321 | alter gene pair correl potenti diagnost marker colon cancer colorect cancer crc lead caus death cancer canada earli detect crc remain crucial manag diseas prognosi improv patient surviv also facilit prevent screen treatment diseas progress chronic stage studi develop strategi identifi colon cancer biomark gene express ... | D003110 | T191 |
36,293,320 | kdf novel variant caus uniqu dental oral epitheli defect keratinocyt differenti factor kdf recent identifi rare candid gene human tooth agenesi howev kdf relat morpholog characterist patholog chang dental tissu oral epithelium remain larg unknown employ whole exom sequenc wes sanger sequenc screen suspect variant cohor... | D000848 | T019 |
36,293,319 | identif prognost gene signatur develop scrna seq base integr approach predict recurr chemotherapi benefit stage ii iii colorect cancer prospect identif robust biomark relat prognosi adjuv chemotherapi becom necessari critic step predict benefit adjuv therapi patient stage ii iii colorect cancer crc clinic treatment pro... | D014408;D015179 | T123;T191 |
36,293,318 | genom basi individu differ suscept neurotox effect diesel exhaust air pollut known environment health hazard major sourc air pollut includ diesel exhaust de initi research de focus respiratori morbid howev recent exposur de associ neurolog development disord neurodegener studi investig effect sub chronic inhal exposur ... | D000393;D020258 | T131;T037 |
36,293,317 | critic overview hepat factor link non alcohol fatti liver diseas acut kidney injuri physiolog therapeut implic non alcohol fatti liver diseas nafld defin combin group progress diseas present differ structur featur liver differ stage diseas accord epidemiolog survey live standard improv global preval nafld increas acut ... | D065626;D058186 | T047;T037 |
36,293,316 | estim similar protein pocket exponenti increas public avail protein structur comparison protein bind site natur emerg scientif topic explain observ generat hypothes ligand design notabl predict ligand select target explain polypharmacolog design target focus librari current review summar state art comput method appli p... | D015195;D011506 | T090;T116;T123 |
36,293,315 | identif matur plasma cell index high sensit droplet digit pcr assay gene express signatur valid newli diagnos multipl myeloma patient dna microarray rna base sequenc approach consid import discoveri tool clinic medicin howev cross platform reproduc studi undertaken far highlight microarray abl accur measur gene express... | D010950;D009101 | T191;T025 |
36,293,314 | origin effici antibiot adjuv strategi enhanc activ macrolid antibiot gram negat resist strain gram negat bacteria report signific caus infect communiti nosocomi set consid one greatest threat public health spread bacteria drug resist lack effect altern treatment option remain problemat herein report promis strategi com... | D000900;D006090 | T121;T007;T195 |
36,293,313 | potenti use autogen tendon graft inject bone marrow aspir rabbit meniscectomi model bone marrow aspir bma excel sourc cell growth factor use success bone cartilag soft tissu heal studi aim investig histolog biomechan properti autogen tendon graft inject bma protect effect degen chang rabbit model menisc defect adult wh... | D000074403;D002358 | T061;T024 |
36,293,312 | molecular character plasma hdl ldl vldl lipid cargo atherosclerot patient advanc carotid lesion preliminari report carotid atherosclerosi repres relev healthcar problem sinc unstabl plaqu respons approxim neurolog event name transient ischem attack stroke although statin treatment proven effect reduc ldl cholesterol on... | D019161;D050197;D058226 | T121;T109;T020;T047;T046;T031 |
36,293,311 | nrd mediat cell senesc mous heart deriv sca cd cell sca cd cell resid cardiac progenitor cell found mani mammalian tissu includ heart abl differenti cardiomyocyt vitro vivo previous work indic heart deriv sca cd cell increas nrd mrna level nrd age howev nrd affect senesc sca cd cell | D000950;D008565 | T129;T116;T123;T192 |
36,293,310 | mutat hotspot chang substrat specif n acetylhexosaminidas librari glcnacas n acetylhexosaminidas talaromyc flavus tf hex ec exo glycosidas dual activ cleav n acetylglucosamin glcnac n acetylgalactosamin galnac unit carbohydr target mutat hotspot activ site residu glu prepar librari ten mutant variant substrat specif si... | D001619;D000117 | T121;T126;T116;T109 |
36,293,309 | corticosteron glucocorticoid receptor apcreb axi inhibit lutein hormon receptor express mous granulosa cell stress condit lutein hormon lh mediat ovul inhibit result insuffici oocyt product excret follicular develop bodi stress larg amount corticosteron cort generat lead disord bodi endocrin system damag bodi previous ... | D011974;D003345 | T121;T116;T109;T192;T125 |
36,293,308 | involv il signal pathway anti anhedon effect antidepress agomelatin chronic mild stress model depress neuroinflamm emerg import factor molecular underpin major depress disord mdd pathophysiolog mechan action antidepress among inflammatori mediat dysregul depress patient interleukin il recent propos play crucial role il... | D015850;D003865 | T129;T116;T048 |
36,293,307 | drug resist dapson rifampicin ofloxacin resist relat gene mutat featur leprosi patient systemat review meta analysi dapson dds rifampicin rif ofloxacin ofl drug recommend world health organ treatment leprosi context leprosi resist drug occur main due mutat target gene folp rpob gyra import monitor antimicrobi resist pa... | D012293;D007918 | T121;T047;T195;T109 |
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