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biomedical-topic-categorization-validation

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36,273,195
fraction order differenti equat chronic liver cirrhosi frequent hospit liver cirrhosi consid termin stage liver diseas becom life threaten among non communic diseas world viral hepat hepat b c major risk factor develop progress chronic liver cirrhosi asymptomat stage cirrhosi consid compens cirrhosi wherea symptomat stage consid decompens cirrhosi latter stage character complex disord affect multipl system liver organ frequent hospit paper formul system fraction differenti equat chronic liver cirrhosi frequent hospit investig dynam diseas fundament properti includ exist posit solut posit invari set biolog feasibl discuss use general mean valu theorem establish exist posit solut adam type predictor evalu corrector evalu approach use present numer scheme fraction erder model
D008103;D006509
T047
36,273,194
acinar atpblpc pathway promot macrophag efferocytosi clearanc inflamm chronic pancreat develop noninflammatori clearanc die cell profession phagocyt term efferocytosi fundament homeostasi inflammatori fibrosi diseas confirm occur chronic pancreat cp investig whether efferocytosi constitut novel regulatori target cp mechan prss transgen prss tg mice treat caerulein mimic cp develop phospholipid metabolit profil epigenet assay perform prss tg cp model potenti function atpb cp model clarifi use atpb overexpress adeno associ virus immunofluoresc enzym link immunosorb assay elisa lipid metabolom approach atac seq combin rna seq use identifi transcript factor bind atpb promot chip qpcr luciferas assay use confirm identifi transcript factor bound atpb promot identifi specif bind site flow cytometri perform analyz proport pancreat macrophag decreas efferocytosi aggrav inflamm identifi cp lysophosphatidylcholin lpc pathway obvious dysregul phospholipid pathway lpc atpb express gradual decreas cp develop hkme chip seq show increas atpb promot methyl led transcript inhibit atpb complement substanti increas lpc concentr improv cp outcom bhlha identifi transcript factor bind atpb promot regul phospholipid metabol studi indic acinar atpblpc pathway act import find signal macrophag play protect role cp atpb transcript promot acinar cell specif transcript factor bhlha bhlha atpb lpc could clinic translat valuabl therapeut target overcom limit current cp therapi
D000251;D008244;D008264;D050500
T116;T025;T109;T126;T047
36,273,193
heparin induc thrombocytopenia follow shiga toxin associ hemolyt urem syndrom case report case shiga toxin produc escherichia coli hemolyt urem syndrom occur adult clinic present variabl microbiolog analys must perform patient thrombot microangiopathi identifi shiga toxin produc escherichia coli even absenc diarrhea
D006463;D054323;D057049;D000743;D004927
T047;T007
36,273,190
reliabl valid japanes version weight bias intern scale weight bias intern scale wbis wide use sever languag howev japanes version wbis purpos studi develop japanes version wbis verifi reliabl valid translat origin version wbis approv scale develop adult perceiv obes complet onlin baselin survey n two week follow survey n use japanes wbis scale obes relat qualiti life self esteem self efficaci depress calcul cronbach alpha intra class correl coeffici icc assess reliabl wbis conduct confirmatori factor analysi cfa correl analysi assess valid
D011788;D000079322
T078;T054
36,273,189
dexmedetomidin allevi inflammatori respons oxid stress injuri vascular smooth muscl cell via argsk mkp nrf axi intracrani aneurysm vascular smooth muscl cell vsmc phenotyp modul regul initi progress intracrani aneurysm ia dexmedetomidin dex suggest play neuroprotect role patient craniocerebr injuri therefor investig biolog function dex mechan ia format progress current studi rat primari vsmcs isol spragu dawley rat ia superfici tempor arteri sta tissu sampl obtain patient ia flow cytometri conduct identifi characterist isol vsmcs hydrogen peroxid h use mimic ia like condit vitro cell viabil detect use cck assay wound heal transwel assay perform detect cell motil ros product determin immunofluoresc use dcfh da probe western blot rt qpcr carri measur gene express level inflamm respons determin measur inflammatori cytokin immunohistochemistri stain conduct measur adrenerg receptor level tissu sampl dex allevi h induc cytotox attenu promot effect h cell malign protect vsmcs h induc oxid damag inflamm respons dex regul gsk mkp nrf pathway via ar dex allevi inflammatori respons oxid damag vsmcs regul gsk mkp nrf pathway via ar ia
D020927;D002532
T121;T190;T109;T047;T046
36,273,187
cognit behaviour therapi optim post oper fractur recoveri cope protocol random control trial chronic non cancer pain affect approxim popul north america europ australia surgeri trauma frequent cite incit event prospect studi fractur patient demonstr associ somat pre occup poor cope low recoveri expect follow surgeri persist pain function limit lower rate return work psycholog intervent cognit behaviour therapi cbt design modifi unhelp belief behaviour potenti reduc persist post surgic pain associ effect among trauma patient
D015928;D050723;D005596;D059350
T061;T184;T047;T037
36,273,186
high dose intens modul proton therapi versus standard dose intens modul radiat therapi esophag squamous cell carcinoma hi siri studi protocol random control clinic trial chemoradiotherapi standard care esophag cancer neoadjuv treatment surgeri definit treatment unresect diseas intens modul radiotherapi imrt consid standard radiat techniqu howev patient suffer treatment relat toxic die diseas progress recurr emerg technolog advanc proton therapi theoret advantag imrt offer appar dosimetr benefit allow dose escal target better spare surround tissu lung heart liver spinal cord purpos studi protocol investig surviv benefit proton therapi use modern intens modul proton therapi impt compar standard imrt esophag cancer
D002294;D004938;D000077277;D061766;D050397
T061;T191
36,273,185
identifi child anxieti school identif intervent icat ii protocol cluster randomis control trial compar screen feedback intervent child anxieti problem usual school practic systemat screen child anxieti problem offer deliv brief evid base intervent children identifi like benefit would minimis common barrier famili experi access treatment develop short parent report child anxieti screen questionnair procedur administ screen questionnair share screen outcom famili offer deliv brief parent led onlin intervent osi onlin support intervent child anxieti school trial aim evalu clinic health econom outcom children age screen posit anxieti problem baselin target popul wider popul children particip class total popul school random alloc receiv identif intervent procedur usual school practic screen intervent compar assess usual school practic usual school practic method trial design parallel group superior cluster randomis control trial school cluster randomis screen intervent usual school practic arm ratio stratifi accord level depriv within school recruit school particip two phase pilot phase phase phase progress criteria assess prior progress phase total trial recruit primaryjunior school england children per arm screen posit anxieti problem baselin target popul school alloc screen intervent parentscar complet brief parent report child anxieti screen questionnair baselin receiv feedback child screen outcom randomis class receiv lesson manag fear worri staff provid inform intervent parentscar children screen posit anxieti problem target popul offer osi osi also avail parentscar children particip class total popul request collect child parent teacher report measur target popul total popul baselin randomis month month month post randomis primari outcom proport children screen posit anxieti problem baselin target popul screen negat anxieti problem month post randomis
D012574;D001007
T184;T073;T092;T041;T048
36,273,184
advanc sex dispar cancer immunotherapi unveil dilemma yin yang wide sex dispar demonstr cancer incid tumor aggress prognosi treatment respons differ type cancer sex specif cancer appear relev issu manag diseas studi investig role sex gender becom extrem urgent immunotherapi play lead role cancer treatment offer new perspect advanc malign gender consid standard cancer treatment suggest increas recognit sex differ cancer research clinic manag paper provid overview sex gender dispar cancer immunotherapi efficaci anti cancer immun respons predict biomark focus molecular differ male femal patient across broad rang cancer type arous attent practic clinician research sex perspect new cancer treatment strategi
D014408;D009369
T123;T191
36,273,183
strategi improv qualiti wheat flour bread chain iran perspect differ stakehold bread constitut signific energi sourc provid protein essenti micronutri larg popul worldwid includ iran qualiti characterist import health studi aim identifi view experi various stakehold involv wheat flour bread chain factor affect qualiti chain strategi improv iran
D001939;D005433
T168
36,273,182
statist analysi plan step wedg clinic trial heal right way enhanc rehabilit servic aborigin australian brain injuri aborigin australian known suffer high level acquir brain injuri stroke traumat brain injuri yet experi signific barrier access rehabilit servic aim heal right way trial evalu cultur secur intervent aborigin peopl newli acquir brain injuri improv rehabilit experi qualiti life follow public trial protocol paper outlin statist analysi plan prior lock databas method trial involv step wedg design four step year particip adult aborigin australian admit one eight hospit four rural four urban western australia within week onset new stroke traumat brain injuri consent follow week hospit site start control phase intervent assign pair site one metropolitan one rural everi week site receiv intervent two compon intervent involv train cultur safe care hospit site enhanc support provid particip aborigin brain injuri coordin hospit stay discharg primari outcom qualiti life measur euro qol l vas mix effect linear regress model use assess group differ week post injuri model control injuri type sever age recruit time sinc commenc trial fix effect recruit site particip includ random effect secondari outcom includ measur function independ anxieti depress carer strain alli health occas servic receiv hospit complianc minimum process care base clinic guidelin best practic model care
D000070642;D020521
T047;T037
36,273,181
efficaci safeti jiu wei xi feng granul treat tic disord children studi protocol random control equival trial tic disord td neuropsychiatr diseas twitch main manifest childhood jiu wei xi feng granul market china treat children td long gu os draconi composit chines patent medicin rare expens medicin materi protect chines govern therefor consid replac mu li concha ostrea effect cheaper studi design evalu clinic equival jiu wei xi feng granul os draconi replac concha ostrea jwxfd jiu wei xi feng granul origin formula jwxfo children td consumpt renal yin liver wind stir intern syndrom
D020323;D013981
T184;T047;T037;T048
36,273,180
efficaci emot focus therapi among spanish speak coupl studi protocol random clinic trial argentina costa rica guatemala mexico spain coupl relationship distress common associ poor physic psycholog relat outcom partner emot focus therapi coupl eft short term structur approach base attach theori integr humanist experienti approach restructur emot experi system structur approach restructur interact model shown effect treatment coupl distress support research howev conduct english speak coupl despit spanish second spoken languag meaning cultur differ english spanish speak countri efficaci eft examin cultur context studi examin efficaci eft particular context advanc understand potenti mechan chang
D000071441;D019546
T061
36,273,179
interact factori randomis clinic stepcar trial potenti effect conclus protocol simul studi randomis clinic trial factori design may assess effect multipl intervent popul factori trial carri assumpt trial intervent interact outcom present protocol simul studi investig consequ differ level interact trial intervent outcom futur factori design randomis clinic sedat temperatur pressur cardiac arrest resuscit stepcar trial comatos patient hospit cardiac arrest
D012107;D058687
T062;T096;T170;T081;T046;T169
36,273,177
identif dna methyl regul differenti express gene ra integr analysi dna methyl rna seq data identifi novel dna methyl regul differenti express gene medeg ra integr analysi dna methyl rna seq data
D001172;D019175
T047;T044
36,273,174
shp knockdown suppress mitochondri biogenesi aggrav mitochondria depend apoptosi induc tran retin stingampk pathway oxid stress caus damag retin pigment epithelium rpe under onset progress age relat macular degener amd impair mitochondri biogenesi sensit rpe cell mitochondri dysfunct energi insuffici death src homolog domain contain phosphatas shp import regul immun respons cell surviv howev role cell surviv alway consist effect shp rpe dysfunct especi mitochondri homeostasi remain elucid sought clarifi effect shp rpe cell respons atral induc oxid stress determin regulatori mechan involv
D008268;D008928;D055213;D012172
T026;T123;T121;T127;T109;T023;T043;T047
36,273,173
xanthohumol microbiom signatur adult crohn diseas xmas trial protocol phase ii tripl mask placebo control clinic trial xanthohumol xn bioactiv flavonoid humulus lupulus anti inflammatori properti potenti benefit patient crohn diseas cd type inflammatori bowel diseas recent complet publish result placebo control phase clinic trial demonstr safeti toler mg xn daili week present studi aim evalu safeti toler dose xn adult clinic activ cd placebo control phase ii clinic trial addit aim assess impact xn inflammatori biomark platelet function cd clinic activ stool microbi composit metabol xn also evalu articl provid model protocol consider investig xn natur product diseas state
D003424;D064307;D001688
T123;T121;T032;T028;T047;T001
36,273,172
genom scale analysi arabidopsi splice relat protein kinas famili reveal role abiot stress adapt near intron contain plant gene undergo altern splice respons either stress plant development cue rna splice perform larg ribonucleoprotein complex call spliceosom conjunct associ subunit serin arginin sr protein undergo extens phosphoryl plant three main protein kinas famili suggest phosphoryl core spliceosom subunit relat splice factor base ortholog human splice relat kinas serinearginin protein kinas srpk arabidopsi fus complement afc pre mrna process factor prpk protein kinas better defin conserv role kinas plant perform genom scale analysi three famili across photosynthet eukaryot follow extens transcriptom bioinformat analysi arabidopsi thaliana srpk afc prpk protein kinas elucid biolog function unexpect reveal exist srpk afc phylogenet group distinct promot element pattern transcript respons abiot stress prpks possess phylogenet sub divis suggest function redund also reveal splice relat kinas famili diel photoperiod regul implic differ ortholog discret time day rna splice regul foundat work establish number new hypothes regard revers spliceosom phosphoryl contribut diel plant cell regul abiot stress adapt plant
D017360;D029681
T116;T002
36,273,171
patient specif model stroma mediat chemoresist pancreat cancer use three dimension organoid fibroblast co cultur system cancer associ fibroblast caf consid play fundament role pancreat ductal adenocarcinoma pdac progress chemoresist patient deriv organoid demonstr great potenti tumor avatar drug respons predict pdac yet disregard influenc stromal compon chemosensit
D010190;D021441;D000072645;D000970
T121;T191;T025;T109
36,273,170
size select placement pedicl screw use robot assist versus fluoroscopi guid techniqu thoracolumbar fractur possibl implic screw loosen rate increas develop robot technolog accuraci percutan pedicl screw placement howev remain unclear whether robot realli optim select screw size enhanc screw stabil purpos studi compar size diamet length placement accuraci loosen rate pedicl screw use robot assist versus convent fluoroscopi approach thoracolumbar fractur
D065289;D012371;D013123;D050723;D007738
T061;T090;T190;T037;T074
36,273,169
tetrandrin amelior cognit deficit mitig tau aggreg cell anim model tauopathi tauopathi neurodegen diseas associ patholog accumul tau contain tangl brain tauopathi impair cognit motor function observ alzheim diseas ad frontotempor dementia ftd aetiolog tauopathi remain mysteri howev recent studi suggest autophag endolysosom function play essenti role degrad transmiss patholog tau previous demonstr tetrandrin could amelior memori function clear amyloid plaqu transgen ad mice restor autophag endolysosom function howev efficaci tetrandrin associ therapeut mechan tauopathi evalu elucid
D024801;D000544
T047;T048
36,273,168
growth differenti factor associ glycem control patient type diabet mellitus treat metformin post hoc analysi aim studi growth differenti factor gdf newli discov promis target metformin studi aim investig relationship gdf glycem control metformin treatment patient type diabet mellitus
D003924;D055436;D007004;D008687
T129;T121;T116;T109;T039;T047
36,273,167
role whole brain radiotherapi wbrt primari central nervous system lymphoma altern asct consolid follow hd methotrex base induct low incom set primari central nervous system lymphoma pcnsl rare aggress malign although potenti curabl prognosi remain dismal treatment base high dose methotrex hd mtx rituximab follow consolid therapi whole brain radiotherapi wbrt autolog stem cell transplant asct current consensus best consolid strategi better outcom asct obtain condit regimen base thiotepa high cost drug restrict use resourc constrain set latin american data clinic outcom prognost factor therapeut manag pcnsl virtual unknown
D018380;D016543;D008223
T061;T191
36,273,166
health status associ factor middl age older adult cancer survivor india result longitudin age studi india number person surviv cancer increas india elsewher due advanc detect treatment diseas howev evid standardis number cancer survivor characterist complex health challeng nation level exist due data limit studi therefor examin profil cancer survivor health status use recent releas longitudin age studi india lasi survey data
D000073116;D009369;D012893
T201;T191;T047;T101;T048
36,273,165
clinic review hiv integras strand transfer inhibitor insti prevent treatment hiv infect integras strand transfer inhibitor insti improv treatment human immunodefici virus hiv current four approv use treatment nave individu live hiv includ first generat raltegravir elvitegravir second generat dolutegravir bictegravir recent insti cabotegravir approv treatment hiv infect adult replac current antiretrovir therapi individu maintain virolog suppress stabl antiretrovir regimen without histori treatment failur known resist compon pre exposur prophylaxi individu risk acquir hiv infect cabotegravir administ intramuscular month bi month inject depend indic long act combin associ treatment satisfact clinic studi may help individu difficulti take daili oral medic worldwid second generat insti prefer treatment nave individu advantag insti includ high genet barrier resist limit drug drug interact excel rate virolog suppress favor toler insti resist associ mutat report clinic trial involv dolutegravir bictegravir cabotegravir advantag specif insti includ use various popul infant children acut hiv infect individu childbear potenti common advers event observ clinic studi involv insti includ diarrhea nausea insomnia fatigu headach low rate treatment discontinu versus compar group long term clinic implic weight gain associ second generat insti dolutegravir bictegravir warrant studi review summar key clinic consider insti term clinic pharmacolog drug drug interact resist provid perspect clinic decis make addit summar major clinic trial evalu efficaci safeti insti treatment nave patient live hiv well individu risk acquir hiv infect
D015658;D019427;D019428;D015497
T121;T116;T005;T126;T047
36,273,164
design valid theori base percept concern physic literaci questionnair pregnant women plq pw evid physic literaci play essenti role understand import maintain appropri physic activ therebi prevent ill pregnanc present studi aim design valid physic literaci questionnair focus pregnant women
D037841;D057220
T098;T041
36,273,163
leptospira seropreval associ risk factor healthi swedish dog leptospirosi emerg zoonot infect worldwid caus life threaten diseas dog seropreval swedish dog unknown aim present studi estim seropreval pathogen leptospira healthi dog sweden use microagglutin test mat rapid point care enzym link immunosorb assay elisa evalu risk factor leptospira exposur swedish dog
D007919;D004283;D007922
T047;T007
36,273,162
brief internet deliv cognit behaviour intervent children adolesc symptom anxieti depress covid pandem randomis control trial protocol covid pandem major impact mani differ sphere includ mental health children adolesc especi vulner central nervous system still develop fewer cope resourc adult increas preval depress anxieti symptomatolog report worldwid howev access mental health care limit especi paediatr popul low middl incom countri therefor develop brief internet deliv cognit behaviour intervent children adolesc symptom anxieti depress aim propos studi test efficaci intervent
D015928;D000086382;D000079382
T061;T047;T058;T067
36,273,161
impact random outlier auto segment target radiotherapi treatment plan glioblastoma save time consist contour fulli automat segment target organ risk oar valuabl asset radiotherapi though current deep learn dl base model par manual contour perfect typic error fals posit occur frequent unpredict possibl solv oar far straightforward target structur order tackl problem studi analyz occurr possibl dose effect autom delin outlier
D005909;D050397
T061;T191
36,273,160
comparison differ concentr povidon iodin dilut sitz bath prevent perian infect patient undergo chemotherapi hematolog malign studi protocol random control trial infect one common caus death patient hematolog malign chemotherapi due special locat local warmth humid repeat pollut stool urin characterist wrinkl anatom structur within bacteria hide perian becom site high incid infect infect also high recurr rate high mortal increas econom burden patient delay time treatment reduc qualiti life sever case sepsi occur endang patient life previous studi confirm effect povidon iodin pi prevent perian infect patient hematolog malign chemotherapi report document detail advers event associ sitz bath lack random control trial differ concentr dilut povidon iodin sitz bath therefor evid insuffici henc object paper determin whether povidon iodin diluent sitz bath reduc incid perian infect compar convent perian clean care observ incid perian infect sever perian infect complic relat sitz bath among group treat differ concentr povidon iodin diluent especi high risk patient prone perian infect screen optim concentr
D011206;D019337
T121;T191;T109
36,273,159
analges efficaci local versus proxim nerv block hallux valgus surgeri systemat review hallux valgus hv surgeri orthopaed procedur common caus mild moder postop pain effect manag pain becom import element modern hallux valgus surgic treatment local anaesthet la antinocicept effect control pain howev relat paper evalu strategi depth object current systemat review address demand compar efficaci proxim local block control postop pain follow hallux valgus surgeri
D006215;D009407
T061;T190
36,273,158
simplifi regimen combin low dose rituximab autoimmun enceph neuron surfac antibodi autoimmun enceph ae neuron surfac antibodi nsab present pathogenesi mediat b cell secret antibodi rituximab second line choic treatment ae nsab caus b cell deplet via target cd howev optim protocol dosag rituximab combin first line therapi nsab associ ae remain unclear far studi explor efficaci safeti low dose rituximab combin first line treatment nsab associ ae
D004660
T047
36,273,157
dissect super enhanc driven transcript depend reveal novel therapeut strategi target group subtyp medulloblastoma medulloblastoma common malign pediatr brain tumor group subtyp medulloblastoma g mb exhibit worst prognosi super enhanc ses larg cluster enhanc play import role cancer transcript control cell ident gene oncogen tumor depend gene dissect se driven transcript depend cancer lead identif novel oncogen mechan therapeut strategi target
D008527;D001932;D002528
T191
36,273,156
mitochondri transplant opportun challeng treatment obes diabet nonalcohol fatti liver diseas metabol diseas includ obes diabet nonalcohol fatti liver diseas nafld rise incid preval remain major global health socioeconom burden twenti first centuri despit increas understand diseas lack effect treatment remain ongo challeng mitochondria key player intracellular energi product calcium homeostasi signal apoptosi emerg evid show mitochondri dysfunct particip pathogenes metabol diseas exogen supplement healthi mitochondria emerg promis therapeut approach treat diseas articl review recent advanc use mitochondri transplant therapi mrt treatment
D065626;D003920
T047
36,273,155
hao fountain syndrom genit disord report new possibl associ hao fountain syndrom neurodevelopment disord character global development delay variabl impair intellectu develop signific speech delay male patient report associ hypogonad present less case report literatur
D008607
T048
36,273,154
use cryotherapi treat obstruct papilloma accessori tracheal bronchus case report tracheal papillomatosi relat rare condit limit data success treatment modal knowledg first report describ papilloma aris accessori bronchus furthermor case report demonstr success treatment clinic patient center improv use spray cryotherapi
D001982;D014133;D015619;D010212
T019;T047;T191
36,273,153
exploit dna ligas iii addict multipl myeloma flavonoid rhamnetin dna ligas crucial dna repair cell replic sinc catalyz final step dna break join dna ligas iii lig exert pivot role altern non homolog end join repair alt nhej error prone dna repair pathway often regul genom unstabl cancer multipl myeloma mm base three dimension lig structur perform comput screen identifi lig target natur compound potenti candid counteract alt nhej activ mm
D000072481;D004260;D005419;D009101
T121;T116;T127;T109;T191;T045;T126
36,273,151
person diseas prevent pdp studi protocol cluster random clinic trial us prevent servic task forc recommend primari prevent servic middl age adult difficult
D057286;D011314
T058;T170;T073
36,273,150
linear conform determin viscer leishmaniasi diagnost antigen rk rk recombin antigen rk base kinesin sequenc rk compris kinesin haspb sequenc mainstay serolog diagnosi viscer leishmaniasi vl howev key epitop signific structur conform clear defin particular relat report cross reactiv sera patient malaria schistosomiasi tuberculosi
D007898
T047
36,273,149
effect laparoscop roux en gastric bypass one anastomosi gastric bypass glycem control remiss type diabet mellitus studi protocol multi center random control trial diabar trial metabol surgeri induc rapid remiss type diabet mellitus tdm pauciti high level evid compar efficaci laparoscop roux en gastric bypass rygb laparoscop one anastomosi gastric bypass oagb glycem control also mechan drive convers tdm sever obes subject euglycemia poor understood
D003924;D015390;D009767
T061;T047
36,273,148
presenc ovarian endometrioma advers affect ovarian reserv respons stimul oocyt qualiti ivficsi outcom retrospect cohort studi possibl impact ovarian endometrioma oma vitro fertil ivf outcom remain controversi therefor studi aim assess impact oma ivf cycl paramet includ ovarian reserv respons stimul embryo qualiti pregnanc outcom
D065851;D004715;D007247
T191;T042;T033;T047;T046
36,273,147
clinic characterist plasmodium falciparum infect among symptomat patient present major urban militari hospit cameroon urban malaria receiv insuffici attent literatur preval clinic characterist plasmodium falciparum infect amongst patient present suspect malaria investig major urban hospit douala cameroon particular focus anaemia
D016778;D000740;D008288
T047
36,273,146
fidel vari symbiosi gutless marin worm microbi consortium mani anim live intim associ speci rich microbiom key factor maintain benefici associ fidel defin stabil associ host microbiota multipl host generat fidel well studi terrestri host particular insect longer macroevolutionari time contrast littl known fidel marin anim speci rich microbiom short microevolutionari time scale level singl host popul given natur select act direct local popul studi microevolutionari partner fidel import reveal ecolog evolutionari process drive intim benefici associ within anim speci
D059013;D013559;D000845
T040;T070;T204;T001
36,273,145
role trigger receptor express myeloid cell trem central nervous system diseas trigger receptor express myeloid cell trem member immunoglobulin superfamili main express surfac myeloid cell monocyt macrophag neutrophil play import role trigger amplif inflammatori respons involv develop various infecti non infecti diseas autoimmun diseas cancer recent year trem also found particip patholog process sever central nervous system cns diseas target trem may promis strategi treat diseas paper aim character trem term structur signal pathway express regul ligand pathophysiolog role cns diseas
D002493;D008264;D009000;D009504;D000073871
T047;T116;T025
36,273,144
stori paediatr palliat care qualit studi explor health care profession understand concept share patient stori health care profession hcps may communic attitud valu belief care treatment previous qualit research shown hcps usual associ paediatr palliat care ppc death die find concept challeng understand difficult implement attend hcps stori may provid richer account understand ppc thus aim studi explor ppc stori narrat hcps gain increas insight understand ppc entail
D010166;D013727
T061;T058
36,273,143
consumpt culinari prepar ultra process food associ handgrip strength teenag nutrient poor hypocalor diet may associ lower handgrip strength hgs wherea high qualiti balanc diet may associ higher hgs howev studi use nova system classifi food degre process
D018737;D004038
T081;T040;T061
36,273,142
predictor shorter longer term mortal covid present among dialysi patient parallel use machin learn model latin north american countri develop machin learn model understand predictor shorter intermedi longer term mortal among hemodialysi hd patient affect covid four countri america
D000086382
T047;T067
36,273,141
patient want clinician ask social need includ inform medic record social need screen primari care may valuabl address non medic health relat factor hous insecur interfer optim medic care yet unclear patient welcom screen comfort inform includ electron health record ehr
D057286;D003695
T058;T170;T073;T093
36,273,140
circ promot ovarian cancer develop via regul hsamir pslca axi circular rnas circrna appear import modul ovarian cancer aim explor role mechan circ ovarian cancer
D035683;D010051;D000079962
T123;T191;T114
36,273,139
intern depict cost function independ limit among older adult live communiti systemat review cost impair studi function independ limit restrict older adult self suffici reduc qualiti life systemat review cost impair studi examin cost function independ limit among communiti dwell older adult societi health care system person
D000085542;D011788
T033;T078
36,273,138
clinic effect patellar resurfac resurfac select resurfac primari total knee replac systemat review meta analysi intervent observ evid patellar resurfac option total knee replac tkr surgeon alway resurfac patella never resurfac other select resurfac resurfac strategi provid optim outcom unclear assess effect patellar resurfac resurfac select resurfac primari tkr
D010329;D019645
T061;T023
36,273,137
transcriptom popul structur glassi wing sharpshoot homalodisca vitripenni vari insecticid resist southern california homalodisca vitripenni germar glassi wing sharpshoot invas insect california critic threat agricultur transmiss plant pathogen xylella fastidiosa quarantin broad spectrum insecticid biolog control use popul manag h vitripenni sinc invas subsequ prolifer throughout california recent wide spread neonicotinoid resist detect popul h vitripenni southern portion california central valley order better understand potenti mechan h vitripenni neonicotinoid resist perform rna sequenc wild caught insecticid resist relat suscept sharpshoot profil transcriptom popul structur
D006430;D007306
T131;T204
36,273,136
studi compar outcom obes nonobes patient lumbar disc herniat undergo surgeri studi swedish nation qualiti registri patient studi aim evalu whether increas grade obes associ inferior outcom lumbar disc herniat ldh surgeri
D007405
T047
36,273,135
quantit analysi transcriptom dynam provid novel insight development state transit embryogenesi development potenti initi pluripot cell becom progress restrict transit lineag restrict state pluripot cell xenopus blastula stage embryo ideal system studi cell state transit development decis make gene express dynam follow high tempor resolut
D059467;D018507
T081;T045;T086
36,273,134
foxp express retin pigment epitheli cell transcript factor potenti relev patholog age relat macular degener forkhead box protein p foxp transcript factor marker regulatori cell convert naiv cell treg downregul effector function cell previous detect express foxp retin pigment epitheli rpe cell form outer blood retina barrier immun privileg eye
D008268;D055213
T047;T023
36,273,133
rare case report recurr atyp meningioma multipl metastas treat anti pd anti vegf therapi meningioma common type primari intracrani tumor primari meningioma report develop metastas howev proven therapeut strategi multipl metastas meningioma
D008579;D008577;D001932
T191
36,273,132
compar biolog effect guid plan optim strategi cranial proton therapi potenti challeng introduc compar multipl biolog effect guid bg proton plan optim strategi minim variabl relat biolog effect rbe induc dose burden organ risk oar maintain plan qualiti constant rbe
D061766
T061
36,273,131
novel signatur model base mitochondri relat gene predict surviv colon adenocarcinoma colon cancer foremost reason cancer relat mortal worldwid colon adenocarcinoma constitut colon cancer patient colon adenocarcinoma coad identifi advanc stage emerg increas number novel pathogen mechan treatment role mitochondria develop cancer studi report increas frequenc
D003110;D000230
T191
36,273,130
dynam predict life threaten event patient intens care unit earli predict patient deterior help earli intervent patient greater risk deterior intens care unit icu studi aim appli machin learn approach heterogen clinic data predict life threaten event patient icu
D007362;D000069550
T066;T073;T093
36,273,129
identif novel pathogen tbck variant chines patient infantil hypotonia psychomotor retard characterist faci type ihprf case report infantil hypotonia psychomotor retard characterist faci type ihprf omim autosom recess disord caus biallel pathogen variant tbck gene date diseas report rather limit number describ case caucasian
D009135;D009139
T019;T047
36,273,128
associ fluid balanc mortal heart failur sepsi propens score match analysi fluid resuscit necessari correct sepsi induc hypoperfus contradictori treatment heart failur studi explor associ fluid balanc fb first h icu admiss mortal critic ill patient heart failur sepsi
D018805;D006333
T047;T046
36,273,127
impact addit domin inbreed depress effect genom evalu combin two snp chip canadian yorkshir pig bred china begin genom select chines compani genotyp pig differ singl nucleotid polymorph snp array obtain genom data combin sever imput strategi develop usual addit genet effect consid genet evalu howev domin effect may import trait fit mix linear model either classic genotyp domin effect influenc genom evalu rare studi thus object studi use dataset canadian yorkshir pig compar differ strategi combin data two snp array affymetrix k illumina k identifi appropri strategi genom evalu evalu impact domin effect classic genotyp inbreed depress effect genom predict abil averag daili gain adg backfat thick bf loin muscl depth lmd day kg age total number piglet born tnb first pariti
D000071422
T070
36,273,126
associ triglycerid high densiti lipoprotein cholesterol ratio prediabet cross section studi chines non obes peopl normal rang low densiti lipoprotein cholesterol evid relationship triglycerid high densiti lipoprotein cholesterol tghdl c ratio prediabet pre dm chines non obes peopl normal rang low densiti lipoprotein cholesterol ldl c limit therefor present studi undertaken explor link tghdl c ratio pre dm among non obes chines popul normal rang ldl c
D011236
T047
36,273,125
multipl cerebr infarct due calcifi amorph tumor grow rapid anteced infect decreas rapid detach fibrin antithrombot drug case report calcifi amorph tumor cat heart rare non neoplast intracardiac mass calcium deposit surround amorph fibrous tissu possibl caus cerebr embol even rarer cat associ infect cat anteced infect report knowledg addit although cat patient hemodialysi report grow rapid case report cat grew diminish rapid short period time report case year old japanes woman normal renal function develop multipl cerebr infarct due cat grew rapid associ inflamm anteced infect diminish rapid detach fibrin mass surfac antithrombot drug
D006338;D002114
T047;T191;T046
36,273,124
non communic diseas matern health scope review non communic diseas ncds lead caus ill health among women reproduct age increas import caus matern morbid mortal worldwid reliabl data ncds necessari accur measur respons howev inconsist definit ncds make reliabl data collect challeng aim map current global literatur understand ncds defin operation discuss pregnanc childbirth postnat period method scope review conduct comprehens global literatur search ncds matern health cover year eleven electron databas five region databas exhaust grey literatur search without languag restrict use chart approach synthes interpret data result seven includ sourc defin ncds ncds often defin chronic vari tempor broad spectrum condit includ ncds includ pregnanc specif condit infecti diseas common includ condit hypertens diabet epilepsi asthma mental health condit malign public academ institut high incom countri hic focus pre concept period pregnanc public hic discuss ncds context pre concept care medic contracept health dispar qualiti care contrast public focus low middl incom countri discuss ncds context ncd prevent take life cycl approach advoc integr ncd matern health servic
D000073296;D003920;D011248
T047;T046
36,273,123
associ oral intak magnesium sarcopenia cross section studi sarcopenia common skelet muscl disord elder popul patient sarcopenia increas cost care risk hospit magnesium defici might increas reactiv oxygen speci protein damag purpos studi demonstr relat oral intak magnesium sarcopenia european work group sarcopenia older peopl ewgsop definit
D055948
T047
36,273,122
regul evaa mir p promot hepatocellular carcinoma cell prolifer migrat evaa eva homolog novel protein involv autophagi apoptosi function tumor suppressor human primari cancer includ hepatocellular carcinoma hcc consist downregul sever cancer involv hepatocarcinogenesi still larg unknown
D006528;D008113;D035683
T123;T191;T114
36,273,121
systemat review meta analysi epidemiolog characterist covid children sever individu studi specif countri report rise number pediatr covid case inconsist report clinic symptom includ respiratori gastrointestin symptom well divers report mean age household exposur children epidemiolog characterist covid children fulli understood henc comprehens meta analys need provid better understand characterist
D000086382
T047;T067
36,273,120
complet chloroplast genom sorbus sensu stricto rosacea compar analys phylogenet relationship sorbus sensu stricto sorbus ss genus import econom valu beauti leav flower especi color fruit belong tribe malea famili rosacea compris speci main distribut china go disput infragener classif speci delimit speci morpholog similar aim shed light circumscript taxa within genus phylogenet analys perform use sorbus ss chloroplast cp genom newli sequenc repres two subgenera eight section
D054628;D031994;D027824
T002;T028
36,273,119
integr analysi mirna mrna profil reveal potenti role mirna sheep hair follicl develop merino sheep exhibit high wool product excel wool qualiti fleec merino sheep predomin compos wool fiber grown hair follicl hfs hf complex biolog system involv dynam process govern gene regul gene express regul microrna mirna mirna inhibit posttranscript gene express specif bind target messeng rna mrna play import role regul gene express cell cycl biolog develop sequenc purpos studi examin mrna mirna bind identifi key mirna target gene relat hf develop provid new import insight fundament mechan regul cellular activ cell fate decis within outsid skin
D020869;D035683
T063;T123;T059;T114
36,273,118
function status caregiv burden patient mainten haemodialysi cameroon two centr cross section studi data function status fs patient mainten haemodialysi mhd caregiv burden cgb ssa patient fewer week dialysi session pay pocket dialysi relat cost spars object assess function status patient mhd cameroon burden caregiv determin factor associ function status impair fsi high caregiv burden hcgb method consecut enrol patient mhd bamenda region yaound general hospit period month includ patient mhd month caregiv patient andor caregiv document dementia exclud face face interview fs assess combin self report instrument basic activ daili live use lawton brodi katz lbkq scale cgb assess use zarit caregiv burden scale zcgbs defin function status impair fsi score lbkq scale high cgb zcgbs score data analys use ibm spss version result total patient caregiv cgs enrol mean age patient year n male wherea mean age cgs year n femal total patient function status impair fsi n caregiv experienc burden classifi moder high anaemia aor ci p high daili pill burden aor ci p independ associ fsi age caregiv year aor ci p independ associ high cgb strong posit correl fs cgb
D000084802;D000203
T056;T080;T041;T048
36,273,117
genet paramet colostrum calf serum antibodi swedish dairi cattl suffici igg content colostrum essenti newborn calf provid passiv immun substanti affect probabl surviv rear failur passiv transfer fpt occur calf absorb enough antibodi colostrum defin igg concentr calf serum lower gl apart delay access colostrum fpt due low product igg mother poor igg absorpt calf aim studi estim genet background antibodi level indic trait antibodi colostrum calf serum correl milk product
D003126;D007074
T129;T121;T116;T031
36,273,116
preval prediabet diabet vari ethnic among us asian adult healthi weight overweight obes rang electron health record studi asian adult develop type diabet lower bodi mass index bmi compar racialethn group examin variat preval prediabet diabet among asian ethnic group within weight strata compar middl age chines filipino south asian white adult receiv care integr healthcar deliveri system
D011236;D003924
T047
36,273,115
medium chain triglycerid may improv memori non dement older adult systemat review random control trial ketosi exploit neuroprotect impact treatment neurolog condit via keton product exogen medium chain triglycerid mct supplement may induc nutrit ketosi aim systemat review explor effect mcts memori function older adult without cognit impair
D007657;D007662
T123;T109;T033;T047;T046
36,273,106
singl cell sequenc deconvolut cellular respons exercis human skelet muscl skelet muscl adapt exercis associ rang health relat benefit cell type specif adapt within muscl incomplet understood use singl cell sequenc determin effect exercis cellular composit cell type specif process human skelet muscl intens exercis fifteen cluster origin six differ cell popul identifi cell popul remain quantit stabl exercis larg transcript respons observ mesenchym endotheli myogen cell suggest cell specif involv skelet muscl remodel found three subpopul myogen cell character differ matur stage base express marker pax myod tnni tnni exercis acceler trajectori myogen progenitor cell toward matur increas transcript featur fast slow twitch muscl fiber transcript regul contractil element upon differenti valid vitro primari myoblast cell cell type specif adapt mechan induc exercis present contribut understand skelet muscl adapt trigger physic activ may ultim implic physiolog patholog process affect skelet muscl sarcopenia cachexia glucos homeostasi
D018482;D009119
T039;T023;T067;T024
36,273,102
effect mine water growth characterist ryegrass soil matrix properti irrig mine water improv water resourc util rate allevi water shortag also promot crop growth yield howev long term irrig mine water signific chang physicochem properti soil due uniqu miner content studi two group experi conduct pot experi soilless cultiv use mine water fushun mine area explor effect physiolog photosynthet characterist ryegrass well soil properti mine water irrig inhibit indic evalu studi wherea mixtur clean water mine water stimulatori effect interest stimulatori effect weaken proport mine water increas reach maximum ratio moreov inhibitori effect irrig water weaken proport clean water increas content k na ca mg soil higher soil matrix content nutrient element n p k metal cation increas gradual mine water ratio increas electr conduct increas signific moreov ph soil decreas steadili ie acid increas increas soil salin find indic mixtur mine water fushun mine area clean water ratio could improv physiolog growth photosynthet characterist ryegrass enhanc soil qualiti studi thus provid experiment preced util mine water ecolog restor agricultur irrig could therefor serv basi develop novel strategi environment restor util water resourc
D008129;D012989
T131;T002
36,273,101
singl molecul microscopi profil effect zinc status transcript factor dynam regul transcript complex process involv bind transcript factor tfs specif sequenc recruit cofactor chromatin remodel assembl pre initi complex recruit rna polymeras ii increas evid suggest tfs high dynam interact transient dna singl molecul microscopi techniqu power approach track individu tf molecul diffus nucleus interact dna employ multifocus microscopi high inclin lamin optic sheet microscopi track tf dynam respons perturb labil zinc insid cell sought defin whether zinc depend tfs sens chang labil zinc pool determin whether dynam dna bind modul zinc use fluoresc tag version glucocorticoid receptor gr two c zinc finger domain ccctc bind factor ctcf eleven ch zinc finger domain found gr larg insensit perturb zinc wherea ctcf signific affect zinc deplet dwell time affect zinc elev result indic least transcript factor sensit zinc dynam reveal potenti new layer transcript regul
D014157;D011965
T123;T116;T192
36,273,098
effect aspirin primari prevent cardiovascular diseas mortal among patient chronic kidney diseas chronic kidney diseas associ increas risk cardiovascular bleed event data regard effect risk aspirin therapi primari prevent high risk group patient chronic kidney diseas scant controversi retrospect studi includ patient chronic kidney diseas particip divid accord aspirin use outcom includ non fatal cardiovascular event major bleed event caus mortal among patient met inclus criteria includ propens score match final cohort includ patient mean age year estim glomerular filtrat rate mlminm follow year signific differ caus mortal bleed event odd ratio confid interv p odd ratio confid interv p respect incid cardiovascular event higher aspirin user versus non user univari analysi p compar control possibl risk factor ci p chronic aspirin use primari prevent cardiovascular diseas associ lower mortal cardiovascular event increas bleed among patient chronic kidney diseas result unexpect prompt research field
D002318;D051436
T047
36,273,097
neuromodul depend synapt tag captur retroact control neural code spike neural network event import individu life trigger neuromodul releas brain area respons cognit behavior function well known presenc neuromodul dopamin norepinephrin requir memori consolid impact neuromodul concentr howev less understood recurr spike neural network model featur neuromodul depend synapt tag captur studi synapt memori consolid depend amount neuromodul present minut hour learn find storag rate base spike time base inform control level neuromodul specif find better recal tempor inform high level neuromodul find better recal rate code spatial pattern lower neuromodul mediat select differ group synaps consolid henc result indic minut hour learn level neuromodul may alter process synapt consolid ultim control type inform becom consolid recurr neural network
D008959;D004298
T121;T123;T170;T109
36,273,096
genom sequenc character streptomyc phage pablito repres new speci within genus janusvirus streptomycet ubiquit soil bacteria report complet annot genom sequenc character streptomyc phage pablito isol soil sampl haarlem netherland use streptomyc lividan host phage abl infect divers rang streptomyc strain none belong sister genus kitasatospora phage pablito doubl strand dna genom length base pair encod putat protein could predict presenc serin integras protein indic lysogen natur phage pablito phage remain stabl wide rang temperatur c ph lost infect temperatur c ph drop newli isol phage close relat streptomyc phage janus hank consid new speci classifi genus janusvirus within subfamili arquattrovirina
D001435;D013302
T005;T007
36,273,094
intraop ct assist sacroiliac screw fixat treatment posterior pelvic ring injuri compar studi convent intraop imag pelvic injuri refer disrupt inher structur mechan integr pelvic ring sacroiliac screw fixat techniqu often appli treatment posterior pelvic ring injuri prone iatrogen injuri studi compar intraop postop variabl patient underw sacroiliac screw fixat intraop ct convent imag evalu effect thirti two patient posterior pelvic ring injuri treat sacroiliac screw fixat januari decemb enrol retrospect studi patient divid two group accord differ assist intraop imag subsequ correl data compar analys statist twelv case assign intraop ct group remain twenti case assign convent group signific differ durat surgeri fractur heal time time ambul complic matta radiolog score statist signific differ p sacroiliac screw insert time length incis intraop blood loss qualiti screw posit adjust maje function score especi sexual intercours part assist intraop ct less misposit function impair could achiev satisfactori curat effect could develop sacroiliac screw fixat intraop ct accur ideal method treat posterior pelvic ring injuri
D010384;D050723
T023;T037
36,273,093
cortic midfront theta dynam follow foot strike may index respons adapt reactiv step reactiv balanc recoveri often requir step respons regain postur stabil follow sudden chang postur monitor postur stabil link neuroelectr marker n potenti midfront theta frequenc dynam investig role cortic midfront theta dynam balanc monitor follow foot land reactiv step respons recov whole bodi balanc perturb hypothes midfront theta dynam reflect engag behavior monitor system therefor theta would increas time lock moment foot strike step respons coincid assess postur balanc determin addit step necessari record high densiti eeg kinemat data healthi young particip stood platform deliv multi direct balanc perturb particip instruct recov balanc singl step util either left right leg separ block use target spatial filter general eigen decomposit combin time frequenc analysi eeg data investig whether theta dynam increas follow foot strike event line hypothesi result indic foot strike event elicit midfront theta power increas though backward step counter expect howev theta power increas posit correl margin stabil foot strike suggest differ role foot strike relat theta monitor stabil post hoc analysi suggest midfront theta dynam follow foot land may instead facilit adapt stabil margin subsequ step respons specul increas theta power follow foot strike relat stabil monitor instead may indic cortic dynam relat perform monitor balanc respons
D005528;D004856
T023;T040
36,273,092
fabric character optic properti au decor bi se nanoplatelet au decor bi se nanoplatelet heterostructur fabric two step process thermal cvd c magnetron sputter room temperatur crystal structur bind energi rhombohedr bi se fcc au determin xrd hrtem xps raman spectroscopi xps raman spectroscopi reveal interact au bi se shift bind energi au au au se bi se bond wavenumb g e g mode au decor bi se nanoplatelet heterostructur observ use fesem confirm xps raman spectroscopi hrtem imag optic band gap au decor bi se nanoplatelet heterostructur increas au thick fold much pristin bi se ev owe burstein moss effect optic absorpt au decor bi se nanoplatelet heterostructur reveal increment wavelength nm decrement increas wavelength nm
D013059
T070;T059
36,273,091
ambigu control simul diazotroph world ocean nitrogen fixer diazotroph play key role nitrogen carbon cycl world ocean diazotroph capabl utilis atmospher dinitrogen competit advantag general faster grow ordinari phytoplankton nitrogen deplet condit sun lit surfac ocean studi argu addit competit advantag must play order explain dynam distribut diazotroph global ocean back grow publish evid test effect preferenti graze zooplankton part avoid diazotroph high affin diazotroph phosphorus uptak earth system model intermedi complex result illustr fundament differ model assumpt result similar match observ base estim nitrogen fixat time impli differ trajectori warm futur latter appli biomass fixat rate well ratio two conclud comprehens understand competit ordinari diazotroph phytoplankton reduc uncertainti model base project ocean n cycl
D009586;D010839
T040;T002
36,273,090
larg volum deep brain imag rabbit monkey use compact two photon microscopi vivo imag wide use investig structur function neuron typic locat within cortic surfac due light scatter absorpt difficult perform vivo imag neuron deep cortic subcort region larg anim two photon microscopi combin thin wall quartz capillari grin len attach prism larg volum structur calcium imag neuron locat mm surfac rabbit monkey brain field view great expand rotat chang depth imag probe insid quartz capillari calcium imag layer neuron rabbit motor cortex reveal differenti activ neuron quiet wake slow wave sleep method describ provid import tool studi structur function neuron locat deep brain larg anim
D008853;D002118
T123;T196;T121;T059
36,273,085
hemispher two channel code account binaur unmask human sound nois better detect understood target mask sourc origin differ locat mammalian physiolog suggest neurocomput process under binaur unmask base two hemispher channel encod interaur differ relat neuron activ introduc mathemat formul two channel model complex valu correl coeffici show formul quantifi amount tempor fluctuat interaur differ suggest underli binaur unmask appli model extens librari psychoacoust experi account varianc across eight studi combin physiolog plausibl success explain behavior data propos mechan signific step toward unifi understand binaur unmask encod interaur differ general
D010470;D009622
T067;T069;T041
36,273,080
ponderomot forc system two nanoparticl mechan consequ electromagnet interact two nanoparticl model simul shown local field enhanc effect studi system caus appear local field gradient consequ local field gradient lead ponderomot forc act nanoparticl near surfac work model describ phenomena develop model base near field interact self consist system effect suscept concept use model distribut local field system two differ size nanoparticl calcul ponderomot forc direct valu simul shown system two differ size nanoparticl forc act main surfac bigger nanoparticl system valu densiti per volum unit may acquir sever ten nano newton possibl applic result studi biolog system also discuss
D053758
T073
36,273,079
hunt persecut drive mammal declin iran negat impact human activ biodivers well document howev extinct risk studi incorpor direct human threat particular direct kill remain limit evalu potenti role direct kill hunt persecut indirect human threat via land use chang environment speci trait reproduct rate trophic level among other may play drive mammal speci extinct base data mammal speci iran appli general linear model investig correl extinct risk mammalian speci larg small bodi speci show hunt vulner import predictor affect extinct risk across speci also found small bodi speci impact indirect human influenc wherea larg speci high affect direct kill overal extrins environment factor intrins speci trait lower import model studi give insight domin role direct kill mammal speci declin extinct emphas need account differ sourc threat analys correl extinct risk
D053476;D000090262
T056;T070
36,273,077
effici remov heavi metal ion industri electropolish wastewat use natur materi heavi metal present wastewat generat industri sector pose threat environ includ surfac groundwat resourc mind grow interest find altern yet effect method remov heavi metal ion industri wastewat sorption one techniqu readili appli due simplic high effici product small amount sludg low invest feasibl process wide rang ph temperatur paper deal treatment industri wastewat electropolish stainless steel contain high concentr metal ion fe iii cr iii ni ii cu ii take account effect avail applic biosorb acid wastewat orang peel alga eclipta alba eggshel select studi sorption test carri eclipta alba result obtain show best fit second order kinet model r langmuir isotherm model r maximum adsorpt capac mgg mixtur metal ion potenti use dri calcin eggshel establish materi achiev high remov rate iron chromium remov solut first respect follow nickel copper ion ft ir sem ed measur use character materi togeth laboratori test use real industri effluent made possibl determin mechan action specif surfac area determin test materi valu g eclipta alba dri eggshel calcin eggshel respect result provid ground optim applic select materi industri wastewat treatment
D019216;D014874
T131;T196
36,273,074
ephrina mimet peptid impair fear condit memori reconsolid later amygdala fear memori may undergo process memori reactiv call reconsolid examin role ephrina fear memori reconsolid inhibitori ephrina mimet peptid pep ephrina target epha bind site inhibit epha activ use pep ephrina microinject later amygdala la fear condit rat h train min tone cs memori retriev memori retriev unaffect pep ephrina howev anim impair fear memori test h h afterward compar control fear condit anim inject pep ephrina la immedi long term memori retriev unaffect test h afterward microinject la peptid origin ephrina site interact epha affect fear memori reconsolid rat administr pep ephrina system h fear condit min cs memori retriev impair long term fear condit memori test h afterward compar control peptid result show ephrina bind site need long term fear memori reconsolid la may serv target treatment fear relat disord block reconsolid
D000679;D066272
T023
36,273,073
context depend choic evalu real world consum behavior bodi work span neurosci econom psycholog indic decis make context depend mean valu option depend option question also option choic set context context effect observ primarili small scale laboratori studi tight constrain artifici construct choic set remain determin whether context effect take hold real world choic problem choic set larg decis driven rich histori direct experi investig whether valuat context depend real world choic analyz massiv restaur rate dataset well two independ replic dataset provid complementari operation restaur choic find user make fewer rate maxim choic choic set higher rate option hallmark context depend choic post choic restaur rate also vari systemat rate unchosen restaur furthermor follow laboratori experi use hypothet choic set match real world data find support idea subject valuat restaur scale accord choic context provid corrobor evid general mechanist level account effect taken togeth result provid potent demonstr context depend choic real world choic set manifest decis subject valuat option
D003258;D002755
T055;T054;T080
36,273,072
noxa mcl express influenc sensit bh mimet target bcl xl patient deriv glioma stem cell recurr glioblastoma part attribut high resist subpopul glioma stem cell novel therapeut approach focus restor apoptot program cancer stem cell often deregul bh mimet target anti apoptot bcl famili member emerg promis compound sensit cancer cell antineoplast treatment herein determin abund express anti apoptot bcl famili member bcl xl mcl relev regul patient deriv glioma stem cell surviv expos cell routin use chemotherapeut drug bh mimet abt wehi observ combin bh mimet target bcl xl chemotherapeut agent caus mark increas cell death sensit bcl xl inhibit correl noxa express level interest wherea co target bcl xl mcl led massiv cell death test cell line regul noxa promot cell surviv cell line express higher level bh therefor glioma stem cell efficaci bcl xl inhibit close associ mcl activ noxa express henc potenti effect strategi would consist combin bcl xl inhibitor chemotherapeut agent capabl induc noxa take advantag pro apoptot factor
D000970;D005910
T121;T191;T109
36,273,071
epitheli mesenchym transit inhibit metformin reduc melanoma lung metastasi murin model melanoma aggress cancer fast metastat spread reduc surviv time one common event neoplast progress epitheli mesenchym transit emt enhanc invas cell migrat metastasi studi investig effect metformin emt melanoma cell line b f vitro impact emt downregul melanoma progress vivo metformin cell treatment reduc migrat potenti vitro reduc develop pulmonari metastas express n cadherin vimentin zeb zeb metastas site vivo result indic metformin promot emt downregul impair metastat potenti melanoma cell
D008687;D008545;D008175
T121;T191;T109
36,273,070
environment rna tool marin communiti biodivers assess microscop organ often overlook tradit divers assess due difficulti identifi base morpholog metabarcod method rapid identifi organ environment dna edna use templat howev legaci dna problemat detect organ longer environ sampl environment rna erna produc live organ also collect environment sampl use metabarcod aim studi determin differ communiti composit divers erna edna templat metabarcod use mesocosm contain field collect communiti estuari rna dna co extract sediment librari prepar two loci coi sequenc use illumina miseq result show higher number uniqu sequenc detect erna marker higher divers compar edna signific differ erna edna divers metric also detect studi first demonstr communiti differ detect erna compar edna estuarin system illustr broad applic erna tool assess benthic communiti divers particular environment conserv manag applic
D000080309
T114
36,273,068
wave speed critic patch size integro differ equat strong alle effect simplifi condit given exist posit wave speed integro differ equat strong alle effect unbound habitat result use obtain exist critic patch size equat bound habitat shown wave speed posit exist critic patch size habitat size critic patch size solut persist space wave speed negat solut alway approach zero analyt integr formula develop determin critic patch size laplac dispers kernel use formula show exist multipl equilibrium solut numer simul provid demonstr connect among wave speed critic patch size alle threshold
D008954;D017753
T082;T070;T075
36,273,063
urban dust pollut toler indic select plant speci develop urban greeneri delhi rise urban led increas dust pollut hazard health live be role roadsid plant speci intercept particul matter improv air qualiti well report henc studi carri determin abil various plant speci intercept atmospher dust withstand abiot stress trigger dust deposit present investig three site viz control commerci industri differ anthropogen activ veget select sixteen plant speci entail tree shrub common occur three site select estim dust intercept capac dic impact dust pollut foliag biochemistri toler winter summer season analyz base biochem biolog socio econom paramet air pollut toler index apti anticip perform index api evalu dust load dic found two time higher winter summer season terminalia arjuna ficus benghalensi plumeria alba best dust accumul prosopi juliflora accumul least highest dic observ industri site terminalia arjuna mgcm winter plumeria alba mgcm summer season photosynthet pigment show negat correl dust load ph ascorb acid electrolyt leakag el prolin content show posit correl present studi apti api valu highest ficus religiosa ficus benghalensi alstonia scholari dalbergia sissoo terminalia arjuna plant speci wide canopi larg rough leaf surfac area perfor vein found suitabl henc recommend develop greeneri improv air qualiti urban area like delhi
D000393;D000397
T131;T069;T080
36,273,053
ekc hypothesi valid five high global countri european union empir investig smooth structur shift studi analyz impact global incom ecolog footprint period five high global countri european union rank kof index end studi use fourier autoregress distribut lag cointegr fourier toda yamamoto causal method studi examin effect global environment degrad often neglect structur chang lead bias result use fourier approxim studi first conduct environment assess incorpor smooth structur chang five high global countri european union result show cointegr exist switzerland sweden netherland austria denmark ii ekc hypothesi valid switzerland denmark sweden austria u shape relationship incom ecolog footprint iii turn point incom improv environment qualiti switzerland denmark countri exceed per capita incom level iv global factor promot environment sustain switzerland netherland order regul manag environment issu effect polici maker take advantag econom develop switzerland denmark well global netherland switzerland
D002245;D004784
T123;T197;T057
36,273,041
potenti effect metal ion induc two state allosteri regulatori mechan add adenin riboswitch riboswitch normal regul gene express structur chang respons specif bind cellular metabolit metal ion take add adenin riboswitch exampl explor influenc metal ion especi k mg ion structur dynam riboswitch aptam without ligand use molecular dynam md simul result show two state transit mark structur deform connect j p c j p relat bind cognat ligand also strong coupl chang metal ion environ moreov deform structur c j p transmit p direct connect express platform multipl way affect structur stabil p vari degre final chang regul state riboswitch
D058928;D052157
T123;T114
36,273,038
use bioelectrohydrogenesi left residu futur potenti fertil soil amend current research left residu collect dark ferment microbi electrolysi cell df mec integr system sole biocatalyz activ sludg bioconvers agricultur straw wast hydrogen energi investig feasibl use potenti altern biofertil common cost inorgan one result reveal electrohydrogenesi left residu enrich various plant growth promot microbi communiti includ enterobact paenibacillus mycobacterium pseudomona bradyrhizobium azospirillum mesorhizobium general known abil produc differ essenti phytohormon indol acet acidindol acet acid iaa gibberellin plant growth moreov also contain phosphat solubil nitrogen fix microbi communiti remark provid adequ amount assimil phosphorus nitrogen requir enhanc plant crop growth furthermor macro micronutri includ n p k etc analyz residu detect adequ appreci concentr requir plant growth promot direct applic mec effluent fertil current studi conspicu promot plant growth solanum lycopersicum l tomato capsicum annuum l chilli solanum melongena l brinjal speed flower fruit generat process base find electrohydrogenesi residu could undoubt consid potenti biofertil thus technolog provid new approach agricultur residu control concomit provid sustain cheap eco friend biofertil could replac chemic cost fertil
D005308;D018551
T168;T073;T002
36,273,037
effect plastic fragment plant perform mediat soil properti drought recent year effect plastic contamin soil plant receiv grow attent plastic affect soil water content thus may interact effect drought soil plant howev effect plastic soil high context depend interact drought hard test conduct two greenhous experi test combin effect plastic fragment vari size concentr water avail soil textur soil water content perform plant arabidopsi thaliana plastic fragment stronger negat effect soil water content low water avail shape respons linear vs unimod mediat soil textur convers increas concentr plastic posit effect plant growth suggest plastic fragment introduc fractur point within soil aggreg increas number size soil pore favor water loss also facilit root growth result suggest complex interact effect plastic drought may lead decoupl plant soil respons process taken account ecolog studi agricultur practic
D055864;D017360
T070;T002