PMID int64 35.7M 36.4M | Title/Abstract stringlengths 22 8.78k | MeshTerms stringlengths 7 101 | SemanticTypes stringlengths 4 64 |
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36,234,903 | phytochem red onion grown eco sustain fertil protect mammalian cell oxid stress increas viabil red onion speci great econom import rich phytochem bioactiv compound known medicin properti fertil sulphur bentonit enrich orang residu oliv pomac aim produc onion enrich health benefici compound worldwid great demand minim process food food ingredi function properti new awar import healthi function nutrit life phytochem capac regul metabol process result health benefit red onion bioactiv compound quantiti qualiti vari accord cultiv practic main aim current research determin chemic characterist crude extract red onion bulb differ fertil evalu biolog activ normal oxid stress condit lyophil onion bulb test vitro two cellular model ie hc rat cardiomyoblast cell line primari human dermal fibroblast term viabil oxygen radic homeostasi result evidenc differ phytochem composit antioxid activ extract obtain red onion differ fertil sulphur bentonit fertil contain orang wast oliv pomac posit affect red onion qualiti respect red onion control evidenc sulphur bentonit organ fertil abl stimul plant secondari metabol induc product phytochem healthi function posit effect extract red onion treat fertil particular contain orang wast reduct oxid stress induct cell viabil hc human fibroblast observ show concentr time depend profil result evidenc posit effect relat phenol particular chlorogen p coumar acid flavonol kaempferol present red onion treat low orang residu treat one | D000074385;D031658 | T168;T002 |
36,234,901 | encapsul bromelain combin sodium algin amino acid carrier experiment design simplex centroid mixtur digest evalu bromelain potenti analges anti inflammatori cancer treatment despit therapeut effect protein undergo denatur administ oral microencapsul process shown potenti protein protect control releas system thus paper aim develop encapsul system use sodium algin carrier materi posit charg amino acid stabil agent control releas bromelain vitro test system produc experiment design centroid simplex mixtur character perform ftir show bromelain encapsul system xrd analys show system semi crystallin solid sem analysi morpholog form system follow pattern rough microparticl applic statist analysi show system present behavior evalu quadrat special cubic model p valu lt interact amino acid bromelainalgin evalu free bromelain show reduct protein content enzymat activ end gastric digest furthermor reduct protein content enzymat activ observ end intestin digest lis system show better interact due increas stabil bromelain term amount protein end intestin phase enzymat activ thus studi propos develop ph control releas system aim increas stabil bioavail bromelain intestin system | D000464;D001963 | T116;T122;T121;T109;T126 |
36,234,900 | improv effici organ solar cell methionin electron transport layer interfac modif import way get better perform organ solar cell osc natur biomolecular materi methionin success appli electron transport layer etl invert osc work seri optic morpholog electr character thin film devic use analyz surfac modif effect methionin zinc oxid zno analysi result show surfac modif zno methionin caus signific reduc surfac defect zno optim surfac morpholog zno improv compat etl activ layer better match energi level etl acceptor reduc interfac resist reduc charg recombin enhanc charg transport collect power convers effici pce osc base pm btp ec improv modifi zno methionin work show great applic potenti natur biomolecul methionin osc | D015034 | T121;T197 |
36,234,899 | remedi enzym activ plant tea wast modifi improv effici growth helianthus annuus contamin soil remedi plant enzymat activ cd contamin soil monitor tea wast tea extens use beverag worldwid releas high quantiti tea wast util grow condit helianthus annuus cd metal contamin soil studi plan natur environment condit greenhous purpos four set plant cultiv triplic mark control ii cd stress plant iii dri tea wast cd stress iv fresh tea wast cd stress improv effici biochem reaction plant cd stress tea wast treatment consequ block cd movement soil adsorpt tea wast show tea wast effect control mobil cd soil root plant scan electron microscopi sem valid recoveri leav plant remedi plant growth enzym activ amylas peroxidas nitrat reductas nr nitrit reductas nir cd metal contamin soil tea wast investig sourc tea wast contamin soil result recoveri photosynthet process improv amylas nr nir peroxidas activ therebi result recoveri pigment coupl increas biomass plant suggest tea wast act good biosorb cd energi provid plant normal enzym activ cd stress may use farmer futur safe healthi crop cost effect technolog | D006368;D012989 | T131;T002 |
36,234,898 | hydrogel dress contain basic fibroblast growth factor acceler chronic wound heal age mous model due decreas self repair abil elder peopl easier form chronic wound suffer slow difficult wound heal desir develop novel wound dress acceler chronic wound heal elder subject decreas pain patient save medic resourc work heparin basic fibroblast growth factor bfgf dissolv mix solut arm acryl polyethylen glycol dithiothreitol form hydrogel dress vitro room temperatur without catalyst conveni easi handl clinic applic vitro leas test show bfgf could continu releas least day wherea dress surfac integr maintain day degrad pbs solut three group treatment includ bfgf gel bfgf sol control without treatment appli full thick wound month old mice back wound closur rate histolog immunohistochem stain illustr bfgf gel display better wound heal effect two group thus prepar hydrogel dress seem supe rior current clinic treatment effect elder subject show promis potenti appli clinic | D016222;D020100 | T123;T116;T122 |
36,234,897 | phytochem composit antibacteri antioxid antidiabet potenti cydonia oblonga bark cydonia oblonga medicin plant use treat number health complic tradit medic system object studi evalu phytochem composit antibacteri antioxid ant diabet potenti methanol extract cydonia oblonga bark cydonia oblonga bark extract fraction hplc seven purifi fraction label f f f f f f f obtain hplc uv analysi methanol extract show presenc number possibl compound gc ms hplc analysi confirm presenc follow bioactiv compound crude extract purifi fraction malic acid mandel acid quercetin caffeic acid catechin hydrat morin hplc analysi bis ethylhexyl phthalat diisooctyl phthalat f carbamid f use fertil octasiloxan dimethylsiloxanecyclictrim f silic acid cyclotrisiloxan f ah camp h cyclopropa benz azul chlorophenyl morpholinepyrol yl butenedio acid f isopropyamin f propylhydrazin f extract purifi fraction test biolog activ purifi fraction methanol extract show effect antibacteri activ howev highest activ record methanol extract staphylococcus aureus streptococcus pneumonia antioxid evalu methanol extract purifi fraction dpph show strong inhibit synthet free radic methanol extract exhibit inhibit wherea fraction show f f f f f f f inhibit ascorb acid standard use control inhibit maximum concentr gml glucosidas inhibit assay methanol extract purifi fraction maximum concentr gml show activ methanol extract f f f f f f f inhibit amylas inhibit methanol extract purifi fraction note methanol extract f f f f f f f highest concentr gml acarbos standard show inhibit glucosidas inhibit amylas highest concentr gml found biolog activ methanol extract purifi fraction might attribut fact rich sourc phenol flavonoid along bioactiv compound total phenol flavonoid content methanol extract record higher compar purifi fraction tpc tfc amongst purifi fraction fraction exhibit highest tpc valu purifi fraction exhibit highest valu tfc recent research demonstr cydonia oblonga may consid antibacteri medicin plant result present studi reveal might util isol bioactiv phytochem lead new opportun discoveri new antibiot | D002392;D027824 | T121;T109;T002 |
36,234,896 | peroxyacet acid pretreat potenti promis strategi toward lignocellulos biorefineri stubborn complex structur lignocellulos hinder valor compon cellulos hemicellulos lignin biorefineri industri therefor effici pretreat essenti prerequisit step lignocellulos biorefineri recent consider number studi focus peroxyacet acid paa pretreat lignocellulos fraction breakthrough achiev recent decad articl aim highlight challeng paa pretreat propos roadmap toward lignocellulos fraction paa futur research novel promis pretreat method toward lignocellulos fraction paa strong oxid agent select remov lignin hemicellulos lignocellulos retain intact cellulos downstream upgrad paa lignocellulos pretreat divid commerci paa chemic activ paa enzymat situ generat paa paa lignocellulos fraction show advantag disadvantag meet theme green chemistri enzymat situ generat paa arous great deal enthusiasm lignocellulos fraction furthermor mass balanc techno econom analys discuss order evalu feasibl paa pretreat lignocellulos fraction ultim perspect opportun propos address exist limit paa pretreat toward biomass biorefineri valor summari view green chemistri enzymat situ generat paa becom cut edg topic research lignocellulos fraction futur | D008031;D010463 | T109;T123;T130 |
36,234,894 | optim identif singl mutat hemoglobin variant trifluoroethanol modifi digest method nano lc coupl maldi msms background hemoglobin hb variant aris due point mutat globin chain patholog treatment reli heavili identif natur locat mutat globin chain tradit method diagnosi hplc electrophoresi limit therefor present studi aim develop optim specif method sampl process could lead improv sequenc coverag analysi hb variant nano lc maldi msms method studi primarili standard various sampl process method convent digest trypsin follow acetonitril treatment digest multipl proteas like trypsin glu c lys c trypsin digest subsequ trifluoroethanol tfe treatment final peptid identifi lc maldi msms sampl process step primarili test recombin hb sampl initi optim found tfe method suitabl one effici method appli hb variant identif base high sequenc coverag result develop optim method use organ solvent tfe heat denatur prior digest result sequenc coverag chain sequenc coverag chain help identif hb mutat hb variant protein sequenc databas creat specifi search reduc search time conclus mutat identifi use bottom non target approach therefor sensit robust reproduc method develop identifi singl substitut mutat hb variant sequenc entir globin chain biolog signific infant born annual hemoglobinopathi major caus morbid mortal earli childhood hb variant general aris due point mutat globin chain high sequenc homolog normal hb hb variant chain due high homolog two form identif variant mass spectrometri difficult requir full sequenc coverag chain need suitabl method provid sequenc coverag globin chain variant analysi mass spectrometri studi provid simpl robust reproduc method suitabl lc maldi provid near complet sequenc coverag globin chain method may use near futur routin diagnosi hb variant analysi | D053719;D014270 | T109;T063 |
36,234,893 | effici method birch ethanol lignin sulfat sulfaic acid urea mixtur first time process birch ethanol lignin sulfat sulfam acid urea mixtur dioxan medium optim experiment numer high yield sulfat ethanol lignin contain wt sulfur produc process temperatur c h sampl highest sulfur content wt obtain temperatur c h structur molecular weight distribut sulfat birch ethanol lignin establish ftir h c nmr spectroscopi gel permeat chromatographi introduct sulfat group lignin structur confirm ftir appear absorpt band characterist vibrat sulfat group bond accord nmr spectroscopi data alcohol phenol hydroxyl group ethanol lignin subject sulfat sulfat birch ethanol lignin weight averag molecular weight kda polydispers index obtain optimum process condit differ structur phenylpropan unit birch ethanol lignin syringyl type predomin abi ethanol lignin guaiacyl type predomin manifest fact sulfat former proceed complet moder temperatur latter contrast sulfat abi ethanol lignin sulfat birch ethanol lignin bimod wider molecular weight distribut well less thermal stabil introduct sulfat group ethanol lignin reduc thermal stabil | D029662;D008031 | T109;T123;T002 |
36,234,892 | kribbellichelin b two new antibiot kribbella sp ca activ sever human pathogen current need find new antibiot emerg multidrug resist superbug push scientif communiti come back natur discoveri novel activ structur recent survey halophil actinomyect salin substrat el saladar del margen cllar baza depress granada spain led us isol identif strain rhizospher endem plant limonium majus evalu potenti strain produc new anti infect agent superbug pathogen perform ferment differ cultur media use osmac approach assess antibacteri antifung properti aceton extract studi allow isol two novel antibiot compound kribbellichelin b along known metabolit sandramycin coproporphyrin iii kribellosid c bioassay guid fraction scale activ extract kribbella sp ca strain structur new molecul elucid esi qtof msms nmr marfey analysi determin absolut configur amino acid residu compound assay panel relev antibiot resist pathogen strain evalu cytotox versus human hepatoma cell line hepg atcc hb kribbellichelin b show antimicrobi activ versus candida albican atcc weak potenc acinetobact baumannii mb pseudomona aeruginosa mb atyp dose depend concentr profil aspergillus fumigatus atcc sandramycin confirm previous report excel growth inhibit activ mrsa mb also present clear antifung activ c albican atcc fumigatus atcc associ lower cytotox observ hepg wherea kribellosid c display high antifung activ fumigatus atcc herein describ process follow isol structur elucid potenc evalu two new activ compound panel human pathogen well first time character antifung activ sandramycin | D000192;D000890 | T007;T121 |
36,234,891 | toward predict partit enzym macromolecular phase effect polydispers phase behavior nonaddit hard sphere solut abil separ enzym cell virus mixtur import realiz incorpor mixtur macromolecular solut incorpor may lead spontan phase separ one phase contain major one speci interest inspir phenomenon studi theoret phase behavior model system compos asymmetr binari mixtur hard sphere smaller compon monodispers larger compon polydispers interact model term second virial coeffici could addit hard sphere hs nonaddit hard sphere nah interact polydispers compon subdivid two subcompon averag size ten three time size monodispers compon gave set equat defin phase diagram mixtur two compon solvent calcul theoret liquid liquid phase separ boundari two phase separ binod three phase separ plait point spinod vari distribut polydispers compon skew polydispers vari nonaddit subcompon well main compon compar phase behavior polydispers mixtur binari monodispers mixtur averag size binari monodispers mixtur effect interact found compat polydispers subcompon decreas three phase separ becam possibl shape posit phase boundari depend nonaddit subcompon well size distribut conclud phase enrich polydispers compon demix addit phase incompat subcompon increas | D046911 | T104;T116 |
36,234,890 | theoret studi vinyl sulfon monom effect dopant polyanilin dimer establish structur properti relationship monom polym via theoret chemistri vital design new polym structur specif applic develop bifunct monom select polymeriz site one strategi employ obtain complex polymer system work theoret studi anilinium acrylamid methyl propanesulfon ani amp anilinium styrenesulfon ani ss monom respect dope polyanilin dimer pani amp pani ss perform studi focus understand suscept vinyl group radic attack conform chang result coordin coval bond sulfon aniliniun appli densiti function theori blyp function basi set g p structur ani amp ani ss pani amp pani ss optim differ chemic descriptor determin simul show reactiv vinyl group ani amp slight higher sulfon group undergo conform chang bond pani amp pani ss compar respect bifunct monom addit electroneg pani depend dopant structur thus bond spacer vinyl sulfon group dopant play notabl role final characterist ani amp ani ss pani amp pani ss | D000814;D011108 | T104;T109;T122 |
36,234,889 | product siamenosid mogrosid iv siraitia grosvenorii use immobil glucosidas siraitia grosvenorii type fruit use tradit chines medicin previous studi shown convers saponin often carri chemic hydrolysi problemat environment hazard may caus low yield produc therefor purpos studi establish continu bioreactor immobil enzym produc siamenosid mogrosid iv result show immobil process glucosidas exhibit best relat activ glutaraldehyd ga concentr carrier activ time h bind enzym time h immobil ga linkag highest relat activ glucosidas record reaction substrat c ph subsequ glass microspher immobil glucosidas fill reactor maintain optim activ environ aqueous solut siraitia grosvenorii extract introduc control flow rate highest concentr siamenosid mogrosid iv obtain flow rate mlmin respect develop immobil enzym system siamenosid mogrosid iv prepar larg quantiti industri applic | D019662;D012503;D014315 | T109;T168;T002 |
36,234,888 | recent progress multicompon synthesi pyran deriv sustain catalyst green condit pyran one signific skeleton oxygen contain heterocycl molecul exhibit broad spectrum medicin applic constitu divers natur product analogu various biolog applic pyran analogu contribut growth advanc oxygen contain molecul green one pot methodolog synthesis heterocycl molecul receiv signific attent review focus recent develop synthesis pyran ring deriv use reusabl catalyst emphasis multicompon reaction strategi use green protocol advantag catalyst term yield reaction condit recycl discuss | D001688;D011714 | T121;T109;T123 |
36,234,887 | pyrethroid resist situat across differ eco epidemiolog set cameroon rapid emerg spread pyrethroid resist anophel gambia popul among main factor affect malaria vector control cameroon still enough data exact pyrethroid resist status across cameroon present studi assess pyrethroid resist profil differ eco epidemiolog set cameroon suscept bioassay test perform f gambia femal age three five day mosquito suscept permethrin deltamethrin assess speci gambia sl complex identifi use molecular diagnost tool target site mutat confer resist detect use taqman assay quantit revers transcript real time pcr qrt pcr plex taqman assay use quantif detoxif gene implic pyrethroid resist gambia coluzzii arabiensi identifi differ set gambia domin santchou kkem blabo bertoua njomb coluzzii abund tibati kal high frequenc kdr lf allel rang record almost site ls kdr allel detect low frequenc mosquito popul njomb tibati ny mutat record kal santchou tibati bertoua frequenc vari six cytochrom p gene cypp cypm cypk cypp cypz cypg found overexpress least one popul analysi cuticular hydrocarbon lipid indic signific increas chc content mosquito popul kal njomb compar kkem blabo bertoua popul studi indic high pyrethroid resist across differ ecolog set cameroon differ profil resist across countri present situat call action order mitig impact insecticid resist vector control measur | D000852;D007306;D008288;D011722 | T047;T109;T131;T204 |
36,234,886 | effect black cumin cake addit chemic composit glycem index antioxid activ cook qualiti durum wheat pasta pasta good carrier plant enrich substanc due popular among consum purpos studi investig function potenti optim recip pasta made durum semolina addit black cumin cake level use black cumin cake result statist signific p increas content protein fat ash fiber includ insolubl solubl fraction reduct digest carbohydr content vitro starch hydrolysi index hi observ pasta reduc glycem index gi compar semolina control obtain content polyphenol includ flavonoid cake enrich pasta increas signific p result higher antioxid activ dpph increas iron content time higher sampl addit black cumin cake control sampl function addit signific p increas loss dri matter influenc cook time pasta | D014150;D031881 | T121;T002;T039 |
36,234,885 | brasesquilignan e five new furofuran lignan selaginella braunii baker five new furofuran lignan brasesquilignan e isol aqueous ethanol extract selaginella braunii baker structur elucid extens analysi nmr hresim data absolut configur determin cd spectra enzymat hydrolysi gcms analysi furthermor compound evalu anti prolif activ various human cancer cellsin vitro compound exhibit weak inhibitorypot five human cancer cell | D017705;D032503 | T109;T002 |
36,234,884 | detect verif key intermedi enantioselect peptid catalyz acyl reaction intermedi respons acyl transfer high enantioselect tetrapeptid organocatalyst kinet resolut tran cycloalkan diol never direct observ propos comput methylhistidin moieti acyl intermedi step catalyt cycl studi set investig whether detect character key intermedi use nmr spectroscopi mass spectrometri differ mass spectrometr experi use nano electrospray ionize esi sourc tandem ms techniqu allow identif tetrapeptid acylium ion use differ acyl reagent complex tran cyclohexan diol tetrapeptid also detect addit abl detect acyl tetrapeptid solut use nmr spectroscopi monitor acetyl reaction tran cyclohexan diol find import step toward understand high enantioselect organocatalyst | D003516;D008762 | T109;T116 |
36,234,883 | ocimum speci review chemic constitu antibacteri activ infect bacteria one main problem health use commerci antibiot still one treatment overcom problem howev high level consumpt lead antibiot resist sever type antibiot report experi resist one solut given use natur antibacteri product mani studi report potenti antibacteri activ ocimum plant ocimum known one medicin plant use tradit local peopl plant contain compon secondari metabolit phenol flavonoid steroid terpenoid alkaloid therefor paper discuss five type ocimum speci name americanum basilicum gratissimum campechianum sanctum five speci known contain mani chemic constitu good antibacteri activ sever pathogen bacteria | D031339;D018649;D009822 | T109;T002 |
36,234,882 | cytotox effect rosmarinus officinali extract glioblastoma rhabdomyosarcoma cell line rosmarinus officinali well studi plant known therapeut properti howev biolog activ sever diseas known detail aim studi present new data regard cytotox activ hydroethanol extract rosmarinus officinali glioblastoma rhabdomyosarcoma te cancer cell line chemic composit extract evalu use liquid chromatographi combin time flight mass spectrometri alongsid total phenol content antioxid activ extract show promis time dose depend cytotox activ cell line lowest ic valu cell line calcul h treatment correspond mgml te cell line mgml cell line extract present high phenol content equal mg gaeg dri materi well strong antioxid activ ic valu antioxid assay estim gml dpph assay gml abt assay compound detect abund carnosol phenol diterpen follow polyphenol rosmarin acid presenc phenol compound rhamnetin glucosid hesperidin cirsimaritin notabl preliminari result suggest r officinali potenti altern sourc bioactiv compound examin abil glioblastoma rhabdomyosarcoma | D014150;D005909;D006569;D012208;D027542 | T002;T121;T191;T109;T127;T039 |
36,234,881 | compar investig differ chemic compound raw process mume fructus use plant metabolom combin chemometr method mume fructus well known herbal medicin food long histori process applic differ process method impact intrins qualiti mume fructus thus great signific investig chang chemic compon process ie raw compar pulp charcoal form studi plant metabolom method base mass spectrometri detect establish analyz chemic ingredi mume fructus comprehens chemometr strategi combin analyz profil differ mume fructus differ process method establish strategi identifi volatil non volatil compound mume fructus gas chromatographi mass spectrometri gc ms ultra high perform liquid chromatographi coupl quadrupol time flight mass spectrometri uhplc q tof msms respect moreov orthogon partial least squar discrimin analysi opl da indic raw mume fructus mume fructus pulp charcoal distribut three region subsequ volatil non volatil compon select potenti chemic compon marker variabl import project use vip gt criterion accuraci verifi back propag neural network bp nn understand differ content mume fructus process non volatil chemic compon marker quantit determin ultra high perform liquid chromatographi mass spectrometri uhplc msms result reveal compar raw mume fructus total content compon pulp mume fructus increas decreas charcoal therefor studi use gc ms uhplc q tof msms uhplc msms modern technolog analyz differ chemic compon process mume fructus provid materi basi research qualiti evalu efficaci mume fructus | D004365;D053719 | T121;T123;T063 |
36,234,880 | antioxid activ kinet character chlorella vulgari growth flask level photoheterotroph growth condit c vulgari unicellular microalga whose growth depend condit found synthes primari secondari metabolit differ proport therefor analyz establish condit possibl increas yield metabolit obtain flask level could scale photobioreactor level methodolog screen design appli evalu three factor type substrat sodium acet glycerol substrat concentr exposur time red light photoperiod lightdark respons variabl cell divis biomass substrat consumpt antioxid activ intracellular metabolit abt dpph result sodium acet condit gl photoperiod h light present doubl time td h higher rate divis h final biomass concentr gl addit higher concentr metabolit antioxid activ found sodium acet trolox equival mgl abt trolox equival mgl dpph glycerol photoperiod h light h dark doubl time td h maximum divis rate h biomass concentr end kinet gl sodium acet long photoperiod therefor ideal growth c vulgari scale photobioreactor level | D048408;D058086 | T002;T204 |
36,234,879 | thermochem transit low molecular weight substanc exampl silybin flavonoid silybin complex organ molecul high bioactiv extract plant silybum pharmaceut substanc silybin bioactiv drawn consider attent properti eg thermodynam properti thermal stabil less studi silybin report exhibit melt point valu heat fusion provid work differenti scan calorimetri thermogravimetri includ deriv thermogravimetri infrar spectroscopi microscopi use provid evid silybin exhibit thermochem transit ie soften occur simultan decomposit data avail literatur combin critic discuss result general framework suggest thermochem transit broad effect exhibit various form matter small molecul macromolecul natur synthet organ inorgan increas format hydrogen bond contribut behavior dual influenc inhibit melt b facilit decomposit due weaken chemic bond | D005419 | T121;T109;T127 |
36,234,878 | bioactiv diarylpentanoid insight biolog effect beyond antitumor activ structur activ relationship diarylpentanoid class natur product synthet analog structur relat chalcon gain increas attent due wide array biolog activ includ antitumor anti infect antioxid anti inflammatori antidiabet anti hyperuricem neuroprotect properti previous review diarylpentanoid promis antitumor activ howev view wide rang biolog activ describ class compound purpos review provid detail overview synthet bioactiv diarylpentanoid describ last two decad beyond simpli antitumor effect total compound found highlight main synthet methodolog use synthesi well structur activ relationship studi structur featur activ report collect review highlight diarylpentanoid scaffold promis start point develop new therapeut agent | D001688;D047188 | T121;T109;T123 |
36,234,877 | evalu function characterist certain insect flour non defatteddefat flour protein prepar edibl insect altern sourc protein gain increas attent lead new opportun use food process studi function properti water oil hold capac foam emulsifi properti popular insect form flour defat flour protein prepar gryllus asimilli acheta domesticus zophoba morio studi moreov proxim analysi protein extract yield effici sensori analysi evalu defat flour yield highest protein content insect form test rang signific reduc calorif valu z morio general protein prepar exhibit best function properti among studi form signific differ notic foam capac near higher flour furthermor sampl score well sensori test overal score except z morio flour may exclud use food industri result show insect form studi due good function properti becom valuabl compon food recip posit impact characterist design food | D005433;D005511 | T057;T168 |
36,234,876 | chemic divers essenti oil korean nativ popul agastach rugosa korean mint agastach rugosa baechohyang one import aromat plant nativ republ korea rugosa fragranc use prepar incens sinc goryeo dynasti korea present studi aim explor variat composit essenti oil rugosa among nativ popul korea seed rugosa collect differ site korea seedl rais nurseri essenti oil extract popul steam distil extract method chemic composit analyz gc ms yield essenti oil rugosa rang total compon identifi popul rugosa compon compon common individu rugosa compon select princip compon analysi pca basi essenti oil composit six chemotyp estragol pulegon methyl eugenol menthon isopulegon nepetalacton distinguish accord major compon result cluster analysi individu rugosa could classifi three group estragol methyl eugenol pulegon rugosa exhibit signific chemic divers among individu distribut chemotyp associ collect seed suggest genet divers may influenc variat chemic composit concentr within speci chemic divers serv background select cultivar cultiv industri applic rugosa cultivar high essenti oil yield concentr chemic compon | D031327;D027541;D009822 | T109;T002 |
36,234,875 | homolog model molecular dock molecular dynam simul drug like modifi alpha mangostin tubulin protein acanthamoeba kerat acanthamoeba speci capabl caus amoeb kerat ak monotherapi alpha mangostin effect treatment ak howev bioavail quit poor moreov efficaci therapi conting parasit virul strain improv readi ak necessari find deriv accur target identif beta tubulin bt use target anti acanthamoeba kerat work therefor model bt protein kerat construct homolog model util amino acid sequenc ncbi genbank jq ramachandran plot respons valid protein pdb verifi bt pdb use dock specifi ligand base improv dock score compar alpha mangostin two modifi compound identifi dihydroxi methoxi bis methylbut en yl h xanthen one c dihydroxi bis methylbut en yl h xanthen one c addit molecular dynam simul conduct analyz interact characterist two bound bt new compound complex simul trp arg val gln residu bt c align ident residu bt generat consist hydrogen bond interact howev bt c complex differ bind site tyr ile ser form hydrogen bond rang therefor studi reveal c c inhibit bt addit synergist effect howev vitro vivo studi need | D000048;D015823 | T047;T204 |
36,234,874 | temperatur resist intrins high dielectr constant polyimid flexibl dipol larger permitt materi high dielectr constant polym wide studi concern modern industri induct polar group confirm effect high permitt howev way connect polar group polym backbon mechan effect dielectr properti unclear rare report studi three polyimid c spi c spi c spi rigid backbon differ link group dipol design synthes rigid structur polyimid show excel thermal stabil increas flexibl link group dielectr constant c spi c spi c spi enhanc turn show valu hz respect studi shown flexibl polar group affect dipol polar posit relat dielectr constant base high permitt high temperatur resist polyimid exhibit outstand energi storag capac even c discoveri reveal behavior dipol polym provid effect strategi design high dielectr constant materi | D011108 | T104;T122 |
36,234,873 | phytochem properti vitro biolog activ phenol compound flower clitoria ternatea l phenol compound flower clitoria ternatea l pcfctl extract use high speed shear extract techniqu purifi ab macropor resin phytochem composit purifi phenol compound flower clitoria ternatea l ppcfctl analyz subsequ bioactiv includ antioxid properti enzym inhibitori activ antiprolif activ sever tumor cell line evalu result indic content total phenol flavonoid flavonol flavanol phenol acid ppcfctl increas fold respect compar purifi ab macropor resin result show ppcfctl signific antioxid abil measur reduc power rp ferric reduc antioxid power method frap good dpph abt superoxid anion radic scaveng activ also signific inhibit lipas amylas glucosidas addit morpholog chang hela hepg nci h tumor cell demonstr superior antitumor perform ppcfctl howev acetylcholinesteras inhibitori activ relat weak find suggest ppcfctl import potenti natur antioxid antilipidem anti glycem antineoplast agent health promot food | D031292 | T002 |
36,234,872 | influenc epoxyacid stoichiometri cure behavior mechan properti epoxi vitrim bisphenol epoxi resin cure mixtur dimer trimer fatti acid first epoxi vitrim extens studi howev cure behavior thermal mechan properti epoxi vitrim depend epoxyacid stoichiometri address issu epoxi vitrim three epoxyacid stoichiometri prepar recycl four time differenti scan calorimetri dsc use studi cure behavior origin epoxi vitrim dynam mechan properti mechan perform origin recycl epoxi vitrim investig use dynam mechan analysi dma univers test machin furthermor reaction mechan epoxi vitrim differ epoxyacid stoichiometri interpret increas epoxyacid ratio reaction rate swell ratio glass transit temperatur mechan properti origin epoxi vitrim decreas wherea gel content increas recycl decreas swell ratio elong break origin epoxi vitrim moreov elong break recycl epoxi vitrim decreas epoxyacid ratio recycl time howev gel content tensil strength tough origin epoxi vitrim increas recycl mechan properti epoxi vitrim tune variat epoxyacid stoichiometri | D000143;D004853 | T103;T122 |
36,234,871 | novel chloro n phenyl h indol carboxamid deriv brain type glycogen phosphorylas inhibitor potenti therapeut effect cerebr ischemia brain type glycogen phosphorylas inhibitor potenti new drug treat ischem brain injuri previous studi report compound novel brain type glycogen phosphorylas inhibitor cardioprotect properti also found compound high blood brain barrier permeabl admet predict websit studi deepli analyz protect effect compound hypox ischem brain injuri find compound could allevi hypoxiareoxygen hr injuri astrocyt improv cell viabil reduc ldh leakag rate intracellular glucos content post ischem ros level time compound could reduc level atp brain cell ischemia improv cellular energi metabol downregul degre extracellular acidif improv metabol acidosi could also increas level mitochondri aerob energi metabol brain cell reperfus reduc anaerob glycolysi inhibit apoptosi express apoptosi relat protein result indic compound involv regul glucos metabol control cell apoptosi protect potenti therapeut effect cerebr ischemia reperfus injuri provid new refer possibl develop novel drug treatment ischem brain injuri | D001930;D002545;D020925;D015427 | T047;T046;T037 |
36,234,870 | keratin base composit bioactiv film preserv effect cherri tomato studi keratin extract pig nail wast reduct method use l cystein reduct curcumin success incorpor mix solut includ keratin gelatin glycerin prepar differ kind keratingelatinglycerincurcumin composit film morpholog keratin gelatinglycerincurcumin composit film examin use scan electron microscopi structur molecular interact curcumin keratin pectin examin use fourier transform infrar spectroscopi x ray diffract thermal properti determin thermogravimetr analysi tensil strength keratingelatinglycerincurcumin keratingelatincurcumin composit film mpa respect respect elong break addit compar control group film wrap surfac tomato ratio weight loss keratin gelatin glycerin curcumin experiment group hard valu tomato wrap composit film kgcm final composit film superior antibacteri effect staphylococcus aureus escherichia coli addit curcumin concentr curcumin reach antibacteri activ effect film signific improv diamet inhibit zone e coli mm aureus mm multifunct keratingelatinglycerincurcumin bioactiv film great potenti applic food packag industri | D003474;D018551 | T002;T121;T109;T168;T130 |
36,234,869 | screen humic substanc extract leonardit free radic scaveng activ use dpph method humic substanc hss research long time still manag surpris human today accord latest research addit previous well known effect also antioxid properti howev previous research examin differ antioxid effect fraction extractedproduc differ process consid light absorpt hss falsifi analysi base measur color chang time present work hs fraction obtain leonardit extract process also implement industri scale fraction character elementari analysi uv vis ft ir spectroscopi prove self extract sampl similar characterist intern humic substanc societi ihss standard sampl differ method hs fraction affect element composit spectral characterist antioxid effect investig use dpph method screen antioxid effici humic fulvic himatomelan acid addit compar result ihss standard sampl obtain comprehens pictur antioxid effect hss extract differ way accord dpph method base result extract method affect physico chemic properti also free radic scaveng activ fraction | D000975;D006812 | T121;T109;T123;T044;T039 |
36,234,868 | pilot aquaphotom studi effect audibl sound water molecular structur sound affect medium propag studi biolog system shown various properti aris phenomenon compress media collect mirror water influenc intern extern influenc chang molecular structur accord water molecular structur chang observ whole measur electromagnet emg spectrum use near infrar spectroscopi aquaphotom pilot studi aim better describ understand sound water interact result purifi miner water report similar effect appli hz hz frequenc sound signific reduct spectral variat increas stabil water shown sound perturb general sound rearrang initi water molecular conform chang sampl properti increas strong bound ice like water decreas small water cluster solvat shell even though hz differ appli sound frequenc chang absorb water absorb band specif frequenc also water type depend also mean sound could effect use perturb tool togeth spectroscopi identifi type bio aqueous sampl test well identifi even chang water function | D008900;D014867 | T121;T197 |
36,234,867 | fabric cr znfe g c n heterojunct enrich charg separ sunlight respons photocatalyt perform antibacteri studi lot interest manufactur stabl high effici photocatalyst studi initi cr dope znfe nanoparticl nps made via surfact assist hydrotherm techniqu cr znfe nps modifi incorpor g c n enhanc photocatalyt effici morpholog structur bond aspect analyz xrd ftir sem techniqu photocatalyt effici function cr znfe g c n zfg heterostructur photocatalyst examin mb sunlight produc zfg composit best photocatalyt perform time better znfe g c n respect experi reveal enhanc photocatalyt activ zfg nanocomposit caus effect transfer separ photo induc charg zfg photocatalyst use sunlight treat pollut water propos modif znfe use cr g c n effici afford environment benign visibl light gram posit gram negat bacteria employ zfg ncs antimicrobi activ zfg ncs also exhibit excel antibacteri potenti | D000900;D013472 | T121;T070;T195 |
36,234,866 | vitro antimelanoma properti verbena officinali fraction verbena officinali common use tradit medicin treat mani ailment extract plant therapeut agent potenti treatment differ diseas includ colorect liver cancer explor anti melanoma potenti far goal current work prepar methanol extract fraction use hexan chloroform ethyl acet butanol aceton get semi purifi product semi purifi fraction studi potenc melanoma cell line three potent fraction ha vo ea demonstr inhibit concentr ic valu low gml lox imvi cell line three fraction show similar potenc inhibit growth b cell murin melanoma cell line base high resolut mass spectrometri hrms data first time report lupulon plant lc ms data also indic presenc hedergon acid serjan acid compound v officinali extract | D032412 | T002 |
36,234,865 | erianin load photo respons dendrim mesopor silica nanoparticl explor psoriasi treatment method psoriasi chronic inflammatori skin disord accompani excess keratinocyt prolifer erianin eri ideal drug candid inhibit prolifer induc apoptosi treatment psoriasi howev eri poor water solubl low penetr activ across skin hinder applic local medicin studi develop novel photo respons dendrit mesopor silica nanoparticl base carrier deliv erianin improv bioavail achiev sustain releas effect spiropyran sp aminopropyltriethoxysilan apt perfluorodecyltriethoxysilan pfdtes conjug outer surfac allow eri releas respons uv radiat physicochem properti photo respons dendrit mesopor silica nanoparticl eri dmsn fsp character via multipl techniqu use fourier transform infrar spectromet high resolut transmiss electron microscop nuclear magnet reson nmr spectroscopi anti prolif properti light trigger releas erianin load photo respons dendrit mesopor silica nanoparticl assess via mtt assay drug releas studi vitro erianin load photo respons dendrit mesopor silica nanoparticl uv exhibit signific enhanc hacat cell inhibit efficaci compar formul demonstr extrem low cell viabil concentr mgml indic capabl releas drug respond uv radiat cellular uptak photo respons dendrit mesopor silica nanoparticl dmsn fsp observ via confoc laser scan microscopi clsm experiment result show eri dmsn fsp could effect endocytos cell respond ultraviolet light releas eri achiev effect psoriasi treatment therefor drug deliveri system may promis strategi address question eri deliveri psoriasi therapi | D050091;D053758;D011565 | T047;T104;T073;T122 |
36,234,864 | extract prepar feed supplement contain wood lignan improv intestin health strengthen barrier integr reduc inflamm lignan known exhibit broad spectrum biolog activ indic potenti constitu feed supplement studi investig two extract deriv feed supplement roi protect contain wood lignan magnolol honokiol roi solubl tannin addit aforement lignan protect impact select paramet intestin function antioxid anti inflammatori properti extract determin measur effect reactiv oxygen speci ros pro inflammatori cytokin product vitro impact intestin barrier integr evalu caco cell drosophila melanogast examin leaki gut format furthermor feed trial use infect piglet conduct studi impact level superoxid dismutas glutathion lipid peroxid protect extract lower ros product caco cell revers stress induc weaken barrier integr roi extract inhibit express secret interleukin il interleukin il interleukin il tumor necrosi factor tnf moreov roi extract decreas leaki gut format mortal rate drosophila melanogast dietari supplement protect improv antioxid status barrier integr intestin infect piglet conclus wood lignan enrich feed supplement valuabl tool support intestin health exert antioxid anti inflammatori barrier strengthen effect | D016209;D017705 | T109;T116;T129 |
36,234,863 | head tail head head molecular chain poli p anisidin combin experiment theoret evalu poli p anisidin ppa polyanilin deriv present methoxi och group para posit phenyl ring consid import role conjug polym novel technolog applic systemat combin experiment theoret investig perform obtain insight crystal process ppa convent oxid polymer p anisidin monom base central composit rotat design ccrd effect concentr monom ammonium persulf ap hcl percentag crystallin consid sever experiment techniqu x ray diffract xrd scan electron microscopi sem multifract analysi nuclear magnet reson c nmr fourier transform infrar spectroscopi ftir complex imped spectroscopi analysi addit densiti function theori dft employ perform systemat investig ppa experiment treatment result differ crystal structur percentag crystallin rang ppa ht ppa ht hh broad halo ppa ht hh pattern suggest reduc crystallin needl globular particl morpholog observ sampl needl morpholog might relat crystallin contribut multifract analysi show ppa surfac becam complex crystallin reduc propos molecular structur ppa support high resolut c nmr result allow us access percentag head tail ht head head hh molecular structur compar calcul experiment ftir spectra pronounc chang observ c h n h c c n c due influenc counterion polym backbon well differ mechan polymer final signific differ electr conduct observ rang scm scm respect ppa ht ppa ht hh | D011108 | T104;T122 |
36,234,861 | associ region lactat stage odd chain fatti acid profil triglycerid breast milk china odd chain fatti acid ocfa potenti valu grow infant report breast milk associ locat lactat stage profil content ocfa breast milk studi analyz breast milk sampl collect area china infant formula differ brand purchas local supermarket content sn c signific decreas colostrum matur stage c signific increas lactat stage p gt content c c signific decreas dramat colostrum period content c highest matur stage level c c human milk gansu xinjiang signific higher area similar trend observ level sn c c wherea content sn c c signific higher breast milk shandong base pds la analysi differ among infant formula stage human milk human milk differ locat differ research need determin health benefit associ ocfa | D005227;D008895 | T109;T123;T031;T168 |
36,234,860 | vitro vivo anti arthrit potenti caralluma tuberculata n e brown chemic character present research plan assess vitro vivo anti arthrit potenti caralluma tuberculata n e brown methanol ctme aqueous ctaq extract chemic character done high perform liquid chromatographi gas chromatographi mass spectrometri analysi complet freund adjuv cfa inject left hind paw rat day dose mgkg start th day via oral gavag group except normal diseas control rat given distil water wherea methotrex intraperiton mgkgml administ standard control ctme ctaq exert signific p lt vitro anti arthrit action extract notabl reduc paw edema restor weight loss immun organ weight arthrit score rbcs esr platelet count rheumatoid factor rf c reactiv protein wbcs treat rat plant extract show signific p lt downregul tumor necrosi factor interleukin nf b cyclooxygenas notabl upregul il il b contrast diseas control rat plant extract notic p lt restor superoxid dismutas catalas activ mda level treat rat extract exhibit signific anti arthrit potenti promis potenti exhibit extract probabl due phenol flavonoid compound | D029062;D001169 | T050;T002 |
36,234,859 | synthesi crystal structur theoret calcul antibacteri activ electrochem behavior molecular dock ni ii cu ii complex pyridox semicarbazon new ni ii cu ii complex pyridox semicarbazon synthes structur solv x ray crystallographi analysi show bis ligand octahedr structur ni plsc h h dimer octahedr structur cu plsc h h hirshfeld surfac analysi employ determin import intermolecular interact crystallograph structur structur complex examin use densiti function theori natur bond orbit analysi photocatalyt decomposit methylen blue presenc compound investig compound activ toward e coli aureus minimum inhibit concentr similar chloramphenicol obtain complex led format free radic speci demonstr experi dichlorofluorescein diacet postul mechanist pathway antibacteri photocatalyt activ cyclic voltammogram compound show peak reduct metal ion molecular dock studi show ni ii complex exhibit promis activ toward janus kinas jak potenti therapi inflammatori diseas cancer immunolog disord | D056831;D012664 | T104;T109 |
36,234,857 | thermodynam comput dft studi non coval interact mechan charg transfer complex linagliptin dichloro dicyano benzoquinon ddq chloranil acid cha studi describ non coval interact charg transfer complex ct respons synthesi linagliptin lng dichloro dicyano benzoquinon ddq chloranil acid cha complex acetonitril mecn temperatur c uv vis spectrophotomet util identifi linagliptin lng complex quantit measur linagliptin bulk form uv vis techniqu develop valid accord ich criteria sever aspect includ select linear accuraci precis lod loq robust optim complex synthesi base solvent polar ratio molecul complex associ constant gibb energi g experiment work support comput investig complex util densiti function theori well qtaim nci index rdg accord optim condit beer law observ correl coeffici lgn ddq lgn cha complex respect lgn ddq lgn cha complex lod loq respect approach success use measur lgn bulk form high precis accuraci | D016227;D000069476 | T121;T109 |
36,234,856 | chang fruit qualiti phytochem late matur peach yonglian storag studi chang qualiti paramet sensori influenc paramet peel red flesh white flesh yonglian peach fruit analyz cold storag result indic content total solubl solid tss solubl sugar organ acid vitamin c total anthocyanin phenol flavonoid well good fruit rate vari depend storag stage storag treatment peach fruit map store day favor exterior qualiti good fruit rate higher content total solubl solid tss map signific effect maintain fruit firm content tss solubl sugar organ acid vitamin c total anthocyanin phenol flavonoid among deriv anthocyanin cyanidin pelargonidin found peel content mgkg fw mgkg fw respect howev cyanidin detect flesh content mgkg fw present work differ regard phytochem profil physic properti main correl storag stage storag treatment peach fruit yonglian higher level health promot compound storag maintain favor qualiti | D000872;D000068239 | T121;T109;T168;T002 |
36,234,855 | matur stage discrimin camellia oleifera fruit use visibl near infrar hyperspectr imag matur camellia oleifera fruit one import indic optim harvest day turn result high yield good qualiti produc camellia oil hyperspectr imag hsi system rang visibl near infrar nm employ assess matur stage camellia oleifera fruit hyperspectr imag sampl collect five differ matur stage acquir spectrum sampl extract identifi region interest roi hyperspectr imag spectral princip compon analysi pca reveal first three pcs show potenti discrimin sampl differ matur stage two classif model includ partial least squar discrimin analysi pls da princip compon analysi discrimin analysi pca da base raw pre process full spectra develop perform compar use pls da model base second order nd deriv pre process spectra achiev highest result correct classif rate ccrs calibr cross valid predict set respect key wavelength select pc load two dimension correl spectroscopi cos uninform variabl elimin success project algorithm uvespa appli input pls da model uve spa pls da built optim model highest ccr term predict set confus matrix optim simplifi model satisfactori sensit specif precis acquir misclassif like occur sampl matur stage two three four overal hsi effect select variabl coupl pls da could provid accur method refer simpl system rapid discrimin matur stage camellia oleifera fruit sampl | D028244 | T002 |
36,234,854 | canavalia gladiata pod extract mitig ovalbumin induc asthma onset male balbc mice via suppress mapk asthma one common inflammatori diseas lung worldwid consider progress recent studi treat prevent allerg asthma howev various side effect still observ clinic practic six week old male balbc mice oral administ either sword bean pod extract sbp mgkg dexamethason dex mgkg daili week follow ovalbumin sensit ovaalum intraperiton administr g mgper mous score lung inflamm perform observ patholog chang respons sbp treatment compar ovaalum induc lung injuri addit inflammatori cytokin quantifi serum bronchoalveolar lavag fluid balf lung tissu use elisa western blot analys sbp treatment signific reduc infiltr inflammatori cell releas histamin immunoglobulin e leukotrien serum balf moreov therapeut effect sbp also assess analyz inflammatori chang lung tissu sbp mark suppress activ mapk signal pathway express key inflammatori protein eg tnf th type cytokin il il sbp effect amelior allerg inflamm ovaalum induc asthma suppress pulmonari inflamm | D001249;D011014 | T050;T047 |
36,234,853 | mof high activ catalyst diastereoselect reduct substitut cyclohexanon zr contain mof excel heterogen catalyst diastereoselect meerwein ponndorf verley reduct substitut cyclohexanon presenc substitu posit cyclohexanon ring strong drive reaction toward format one two possibl isom methyl cyclohexanon avail space insid mof pore allow format bulkier transit state lead thermodynam stabl cis cyclohexanol methyl cyclohexanon reaction rate much slower final diastereoselect depend size alcohol use final reduct phenyl cyclohexanon consider faster mof catalyst report far larg size phenyl favor select format select cis alcohol goe less hinder transit state | D003511;D003512 | T121;T109 |
36,234,852 | new insight dietari pterostilben sourc metabol health promot effect pterostilben pts compound abund found blueberri natur analog resveratrol sever plant speci peanut grape produc pts resveratrol extens studi antioxid properti recent evid also point divers therapeut potenti pts sever studi identifi robust pharmacodynam featur pts includ better intestin absorpt elev hepat stabil resveratrol inde due higher bioavail pair reduc toxic compar stilben pts becom attract drug candid treatment sever diseas condit includ diabet cancer cardiovascular diseas neurodegen disord age review articl provid extens summari nutraceut potenti pts various diseas condit discuss crucial mechanist pathway implic particular share insight studi nrf mediat effect pts diabet associ complic moreov elucid import sourc pts discuss detail pharmacokinet rang formul rout administr use across experiment studi human clinic trial furthermor review also summar strategi success use improv dietari avail bio access pts | D051267;D013267 | T109;T123;T116 |
36,234,851 | direct electrooxid selenylationcycl alkyn access function benzo b furan mild practic metal oxid free methodolog synthesi various c selenyl benzo b furan deriv develop intramolecular cyclize alkyn promot diselenid via electrooxid wide rang selenium substitut benzo b furan deriv obtain good excel yield high regioselect constant current undivid cell equip carbon platinum plate anod cathod respect moreov converg approach exhibit good function group toler could easili scale good effici provid rapid access divers rang selenyl benzo b furan deriv simpl readili avail start materi | D000480;D012643 | T121;T109;T123;T196 |
36,234,850 | glucan techno function ingredi dairi milk base product review articl systemat inform sourc glucan technolog function practic aspect use dairi milk base product accord analysi scientif inform main characterist glucan classif consid sourc origin chemic structur method obtent establish popular food technolog dairi product glucan oat barley cereal exhibit pronounc technolog function composit dairi product gel format high moistur bind capac increas yield finish product format textur origin sensori indic expedi use glucan yeast mushroom sourc biolog activ substanc ensur function orient finish product reveal first time inform use glucan various origin common group dairi milk base product systemat analyt review scientif practic signific scientist specialist field food product particular dairi product increas nutrit valu | D008892;D047071 | T121;T109;T168;T031 |
36,234,849 | electrochem investig iron catalyz atom transfer radic polymer use iron base catalyst atom transfer radic polymer atrp interest abund metal biocompat although mechan action well understood yet iron halid salt usual use catalyst often presenc nitrogen phosphor ligand l studi electrochem mediat atrp e atrp methyl methacryl mma catalyz fecl absenc presenc addit ligand investig dimethylformamid electrochem behavior fecl fecl l deepli investig show speciat fe iii fe ii role play ad ligand shown amin ligand form stabl iron complex wherea phosphin act reduc agent e atrp mma catalyz fecl investig differ condit particular effect temperatur catalyst concentr catalyst initi ratio halid ion excess ad ligand investig general polymer moder fast difficult control surpris best result obtain fecl without ligand electrogener fe ii effect activ dormant chain deactiv propag radic fe iii speci less effici result dispers gt unless high concentr fecl use | D007501;D019163 | T121;T123;T130;T196 |
36,234,848 | lysozym applic antibacteri agent food industri lysozym hydrolyt enzym character abil cleav glycosid bond peptidoglycan major structur compon bacteri cell wall hydrolysi action compromis integr cell wall caus lysi bacteria year role antibacteri defens anim renown also use preserv food pharmaceut order improv antimicrobi efficaci lysozym extens research intend modif manuscript review natur antibiot compound lysozym refer catalyt non catalyt mode antibacteri action lysozym type suscept resist bacteria modif lysozym molecul applic food industri | D000890;D009113 | T121;T126;T116 |
36,234,847 | gastrodin amelior cognit dysfunct vascular dementia rat suppress ferroptosi via regul nrfkeap gpx signal pathway gastrodia elata bl long edibl histori consid import function food raw materi gastrodin gas one main function substanc g elata bi use health care product elder enhanc resist delay age studi investig amelior effect mechan gas cognit dysfunct vascular dementia vad rat provid theoret basi develop util function food water maze test show gas improv learn memori impair vad rat meanwhil gas signific decreas level fe malondialdehyd mda increas content glutathion gsh signific regul express nuclear factor erythroid relat factor nrf glutathion peroxidas gpx key regulatori factor ferroptosi regul express kelch like ech associ protein keap cyclooxygenas cox howev gas direct regul gpx cox inhibit ferroptosi furthermor compar gas alon gas combin bardoxolon agonist nrf affect increas gpx level decreas cox level affect regul gas biochem paramet ferroptosi ht hypoxia injuri find reveal gas inhibit ferroptosi hippocamp neuron activ nrfkeap gpx signal pathway suggest possibl applic function food improv vascular dementia inhibit ferroptosi | D060825;D015140;D000079403 | T047;T043;T048 |
36,234,846 | stabil effect induc trehalos creatin aqueous solut investig infrar spectroscopi creatin popular amino acid wide util sport world due function main relat muscl build increas perform present work investig behavior creatin aqueous solut creatin aqueous presenc trehalos function time chang mean infrar spectroscopi infrar spectra gather studi time full spectrum intramolecular oh stretch region two mixtur latter region studi specif use cut edg techniqu call spectral distanc sd analysi spectral featur investig sampl emerg trehalos signific stabil effect creatin aqueous solut | D003401;D014199 | T121;T109;T123;T116 |
36,234,845 | mechanist aspect modul enzym reaction dna scaffold cell develop intellig system implement complex effici enzym cascad reaction via strategi organell bacteri microcompart enzym complex scaffold membran protein cell believ assist co local enzym enhanc enzymat reaction inspir natur enzym locat wide varieti carrier among dna scaffold attract great interest programm address integr properti versatil dna protein conjug method enabl spatial arrang enzym dna scaffold precis control interenzym distanc enzym stoichiometri review survey reaction singl type enzym dna scaffold discuss propos mechan catalyt enhanc dna scaffold enzym also review current progress enzym cascad reaction dna scaffold discuss factor enhanc enzym cascad reaction effici review highlight mechanist aspect modul enzymat reaction dna scaffold | D004247;D011506 | T123;T116;T114 |
36,234,844 | design novel irak inhibitor use molecular dock dynam simul qsar studi treatment sever autoimmun diseas type cancer intens area research past two decad mani signal pathway regul innat andor adapt immun well induc overexpress mutat protein kinas target drug discoveri one serinethreonin kinas interleukin receptor associ kinas irak regul signal various toll like receptor tlrs interleukin receptor ilr control divers cellular process includ inflamm apoptosi cellular differenti myd gain function mutat overexpress irak implic various type malign waldenstrm macroglobulinemia b cell lymphoma colorect cancer pancreat ductal adenocarcinoma breast cancer etc moreov activ irak also associ sever autoimmun diseas signific role irak make interest target discoveri develop potent small molecul inhibitor potent irak inhibitor pf ra bay recent enter phase iii clinic trial studi nevertheless still need select inhibitor treatment cancer various autoimmun diseas great need intrigu us perform molecular model studi diaminonicotinamid deriv irak inhibitor perform molecular dock dynam simul ns one activ compound dataset also carri mm pbsa bind free energi calcul identifi activ site residu interact contribut total bind energi final ns conform activ compound select perform dataset align qsar studi generat rf comfa q onc r model reveal reason statist result overal result molecular dynam simul mm pbsa bind free energi calcul rf comfa model reveal import activ site residu irak necessari structur properti ligand design potent irak inhibitor design irak inhibitor base result possess higher activ predict pic activ compound dataset select studi moreov admet properti inhibitor reveal promis result need valid use experiment studi | D001327;D021281 | T047;T081 |
36,234,843 | remov amoxicillin aqueous media fenton like sonolysish process use zero valent iron nanoparticl high concentr antibiot identifi aqueous media diminish qualiti water resourc compound usual high toxic low biodegrad report mutagen carcinogen effect aim studi appli zero valent iron oxid nanoparticl presenc hydrogen peroxid sonolysi process remov amoxicillin antibiot aqueous media studi zero valent iron nanoparticl prepar iron chlorid reduct method presenc sodium borohydrid nabh obtain nanoparticl character scan electron microscopi sem transmiss electron microscopi tem x ray diffract xrd vibrat sampl magnetometri vsm use fenton like process synthet wastewat contain mgl amoxicillin antibiot investig effect differ paramet frequenc khz contact time min concentr hydrogen peroxid dose zero valent iron nanoparticl gl ph thorough studi ph hydrogen peroxid concentr ultrason wave frequenc khz zero valent iron nanoparticl gl contamin concentr mgl obtain optim condit combin ushonzvi process optim condit combin process zero valent iron nanoparticl hydrogen peroxid presenc ultrason wave remov effici amoxicillin achiev min result show combin ushonzvi process could success use remov environment contamin includ antibiot amoxicillin high remov percentag | D053758;D014874 | T131;T073 |
36,234,842 | silver nanoparticl formul flower head polyphenol cynara scolymus l promis candid prostat pc cancer cell line apoptosi activ cynara scolymus l famili composita artichok nutriti edibl plant wide use hepatoprotect effect crude extract flower bract stem prepar evalu vitro antioxid activ phenol content flower crude extract exhibit highest phenol content mg gaegm well best vitro antioxid activ use total antioxid capac tac ferric reduc antioxid power feap diphenyl picrylhyazyl dpph scaveng assay compar ascorb acid phenol fraction crude extract differ part separ identifi use high perform liquid chromatographi hplc dad analysi silver nanoparticl phenol fraction establish test cytotox apoptot activ result show silver nanoparticl polyphenol fraction flower extract nano tpflower exhibit potent cytotox prostat pc lung cancer cell line ic valu gml gml respect compar doxorubicin standard apoptosi induct nano tpflower exhibit apoptosi pc higher ratio cell induc total prostat apoptot cell death fold chang induc apoptosi cell fold chang nano tpflower upregul pro apoptot marker downregul antiapoptot gene use rt pcr henc extract may serv promis sourc anti prostat cancer candid | D031943;D053768;D009369 | T191;T168;T073;T002 |
36,234,841 | synthesi character silver nanoparticl rhizophora apiculata studi wound heal antioxid anti inflammatori cytotox activ silver nanoparticl agnp recent gain interest medic field biolog featur present studi aim screen rhizophora apiculata secondari metabolit quantifi flavonoid total phenol content green synthesi character r apiculata silver nanoparticl addit assess vitro cytotox antioxid anti inflammatori wound heal activ r apiculata synthes agnp carri powder plant materi leav subject soxhlet extract obtain r apiculata aqueous extract r apiculata extract use reduc agent synthes agnp silver nitrat synthes agnp character uv vis sem edx xrd ftir particl size analyz zeta potenti aqueous leaf extract r apiculata agnp subject vitro antioxid anti inflammatori wound heal cytotox activ skin cancer lung cancer kb oral cancer cell line experi repeat three time n result given mean sem flavonoid total phenol content r apiculata extract mgg quercetin mgg gallic acid respect sem analysi reveal r apiculata agnp diamet rang nm xrd confirm synthes silver nanoparticl crystallin natur cytotox cell viabil assay reveal agnp less toxic ic gml compar r apiculata extract ic gml non cancer fibroblast l cell line antioxid anti inflammatori cytotox test reveal agnp signific activ plant extract agnp inhibit protein denatur mean percentag equival standard anti inflammatori medic diclofenac agnp show consider cytotox effect percentag cell viabil skin cancer lung cancer oral cancer cell line respect r apiculata agnp demonstr stronger cell migrat percentag wound closur compar plant extract overal result reveal r apiculata agnp exhibit potenti antioxid anti inflammatori wound heal cytotox properti futur r apiculata explor unmask therapeut potenti mechanist pathway agnp studi detail vivo anim model | D000970;D053768;D009062;D043982 | T073;T002;T121;T191;T109 |
36,234,840 | effect ultra high pressur endogen enzym activ protein properti qualiti characterist shrimp litopenaeus vannamei ice storag present studi aim explor effect ultra high pressur uhp cathepsin b h l activ protein oxid degrad properti well qualiti characterist ice shrimp litopenaeus vannamei fresh shrimp vacuum pack treat uhp mpa min store c day result show l lumin b yellow w white e color differ hard shear forc gummi chewi resili shrimp signific improv uhp treatment moreov content surfac hydrophob myofibril fragment index mfi trichloroacet acid tca solubl peptid carbonyl dityrosin free sulfhydryl myofibrillar protein mp signific promot uhp treatment addit uhp mpa treatment enhanc mitochondri membran permeabl inhibit lysosom membran stabil cathepsin b h l activ uhp treatment notabl inhibit activ cathepsin delay protein oxid degrad well textur soften shrimp storag general uhp treatment mpa min effect delay protein qualiti deterior caus endogen enzym prolong shelf life shrimp day | D007053;D033561 | T197;T204 |
36,234,838 | comparison atr ftir ptir imag techniqu characteris zinc type degrad product paint cross section atr ftir attenu total reflect fourier transform infrar microscopi imag wide use heritag field characteris complex composit paint cross section howev limit includ need atr crystal contact sampl inabl resolv particl size ir diffract limit recent novel ptir optic phototherm infrar spectroscopi techniqu claim open new avenu non invas effici reliabl analysi sub micron resolut ptir produc transmiss like ftir spectra interpret without need touch sampl high favour attribut analys heritag sampl paper report comparison ptir atr ftir techniqu appli cross section embed thin paint fragment delamin late th earli th centuri oil portrait hazi paint fragment consist zinc soap crystallin amorph gordait nazn cl oh h zinc lactat could well resolv atr ftir imag ptir analysi degrad compound could resolv sub micron resolut equival better signal nois ratio case studi show two techniqu use obtain comprehens inform broad level atr ftir detail level ptir | D010150;D012915 | T073 |
36,234,837 | antifung activ lavandula angustifolia essenti oil candida albican time kill studi pediatr sputum isol aim studi determin suscept candida albican sputum isol fluconazol caspofungin well antifung potenti lavandula angustifolia essenti oil laeo commerci laeo analyz use gas chromatographi mass spectrometri antifung activ evalu use eucast protocol kill assay perform evalu kinet laeo within min treatment laeo major constitu linalool linalyl acet effect inhibit grow c albican concentr rang fluconazol activ note isol mic rang gml surpris isol non wild type non wt mic wt rang gml signific differ laeo mic among fluconazol resist fluconazol suscept sputum strain p neither among caspofungin non wt wt isol p laeo rapid achiev growth reduct test strain min within min laeo concentr exhibit reduct isol studi demonstr solut laeo show signific antifung activ equal effect fluconazol caspofungin suscept less suscept strain | D027523;D009822 | T109;T002 |
36,234,836 | current analyt strategi antibodi drug conjug biomatric antibodi drug conjug adc new class biotherapeut consist cytotox payload coval bound antibodi linker ligand bind assay lba liquid chromatographi mass spectrometri lc ms favor techniqu analysi adc biomatric goal review provid current strategi relat seri bioanalyt assay pharmacokinet pk anti drug antibodi ada assess furthermor strength limit lba lc ms platform compar final potenti factor affect perform develop assay also provid hope review provid valuabl insight bioanalyt scientist use integr analyt strategi involv lba lc ms bioanalysi adc relat immunogen evalu | D018796 | T121;T129 |
36,234,835 | electrochem catalyt properti carbon dioxid activ graphit felt commerci graphit felt gfa subject activ process use co c min pristin heat treat materi character use various method low temperatur n adsorpt sem ed voltammetr measur gfa sampl activ work electrod carri voltammogram record aqueous solut chlorophenol sodium sulfat support electrolyt catalyt activ gfa sampl process chlorophenol oxid use h also investig influenc graphit felt thermal activ co atmospher electrochem catalyt behavior analyz discuss result investig indic gfa activ co appli electrod materi catalyt materi remov organ compound industri wastewat howev corros resist gfa decreas activ need refin | D006108 | T109;T196 |
36,234,834 | azo group function porous aromat framework achiev high effici captur iodin strong radioact iodin compound deriv nuclear power plant wast motiv develop high effici adsorb porous aromat framework paf attract much attent due low densiti divers structur work azo group contain paf solid denot lnu prepar suzuki polymer tris tetramethyl dioxaborolan yl phenyl amin dibromoazobenzen build monom base specif polar proper azo group electron rich aromat fragment hierarch architectur effici captur iodin molecul adsorpt capac mg g wt gaseous iodin mg g wt dissolv iodin iodin uptak per specif surfac area wt g achiev highest level among porous adsorb work illustr success prepar new type porous adsorb expect appli field practic iodin adsorpt | D007455 | T121;T123;T196 |
36,234,833 | situ swell formul glycerol monool deriv lyotrop liquid crystal propos local vagin applic hydrogel extens investig identifi innov formul fulfil necessari purpos improv local vagin therapi mucosa herein propos situ form lyotrop liquid crystal llcs deriv cheap gras general recogn safe ingredi intravagin deliveri system system consist precursor solut load sertaconazol nitrat model drug abl easili swell stabl three dimension structur absorb simul vagin fluid polar light microscopi precursor solut form phase llcs show typic textur belong anisotrop isotrop mesophas respect deep rheolog investig kinexus pro prove stabil strength cubic phase well potenti mucoadhes vitro degrad studi show slow matrix eros consist data obtain lipophil drug releas studi simul vagin fluid therefor suggest cubic phase base lyotrop liquid crystal could repres valid propos vagin drug deliveri system due characterist resist adhes possibl provid slow control releas drug direct administr site | D050866 | T104;T073 |
36,234,832 | essenti oil variabl iranian popul heracleum persicum desf ex fischer rich sourc hexyl butyr octyl acet heracleum persicum desf ex fischer seed rich sourc essenti oil eo high antimicrobi antioxid effect order determin phytochem variabl various iranian h persicum popul seed sampl collect differ climat locat current studi indic hexyl butyr octyl acet hexyl methylbutyr octyl methyl butyr major compon eo maximum minimum content hexyl butyr obtain kaleibar sari popul respect moreov octyl acet content rang mahdasht torghabeh popul ca pca analysi divid iranian h persicum popul three major group popul khanghah kaleibar shebeilo showt mahdasht amin abbad show distinct separ comparison popul high content hexyl butyr low content octyl acet chemotyp ii accord correl analysi highest correl coeffici among habitat elev hexyl butyr content addit mean annual precipit negat correl content hexyl butyr although octyl acet content show high correl soil ec mean annual temperatur statist signific general order plant high content hexyl butyr recommend harvest plant region high altitud low rainfal kaleibar | D000890;D030002;D009822 | T121;T109;T002 |
36,234,831 | detect aflatoxin b peanut fourier transform near infrar transmiss diffus reflect spectroscopi aflatioxin b afb recogn intern agenc research cancer group carcinogen anim human fast batch real time control chemic pollut method develop discrimin quantif predict afb infect peanut appli fourier transform near infrar ft nir coupl chemometr initi near infrar transmiss nirt diffus reflect nirr modul appli collect spectra sampl princip compon analysi pca method employ extract characterist wavelength follow differ preprocess method seven method build effect linear discrimin analysi lda classif partial least squar pls quantif model result show nirt nirr modul lda classif model satisfactorili distinguish peanut infect afb infect extern valid show correct identif rate misjudg rate addit combin concentr afb peanut determin enzym link immunoassay assay best partial least squar pls model establish combin first deriv norri deriv filter smooth pretreat r c rmsecv rpd nirr nirt respect correl coeffici predict valu refer valu extern verif respect studi highlight spectral acquisit modul meet requir onlin rapid accur identif peanut afb infect earli stage | D016604;D010367 | T131;T109;T196;T002 |
36,234,830 | backbon success p n hybrid ligand recent develop organophosphorus ligand invalu famili compound continu underpin import role disciplin coordin chemistri catalysi success routin trace back facil tuneabl thus enabl high degre control exampl electron steric properti diphosphin phosphorus compound bear two separ p iii donor atom also high valu impart uniqu featur exampl excel chelat properti upon metal complex mani classic ligand type backbon connect base carbon spacer grow interest embed donor atom addit nitrogen nh nr site review collat import exampl ligand field illustr role ligand coordin chemistri highlight reactiv applic shown incorpor nitrogen base group impart unusu reactiv import catalyt applic | D002614;D009584 | T121;T123;T130;T196 |
36,234,829 | mass spectrometr identif licania rigida benth leaf extract evalu therapeut effect lipopolysaccharid induc inflammatori respons licania rigida benth evalu altern drug treat diseas associ inflammatori process studi evalu anti inflammatori effect aqueous hydroalcohol leaf extract l rigida inflamm induc lipopolysaccharid vitro vivo inflamm model phytochem profil extract analyz ultra fast liquid chromatographi coupl tandem mass spectrometri reveal presenc gallic ellag acid extract wherea isovitexin ferul bulki amino acid eg phenylalanin pheophorbid lactic acid pyridoxin detect hydroalcohol extract extract display abil modul vitro vivo inflammatori respons reduc approxim pro inflammatori cytokin secret tnf il il inhibit product leukocyt migrat approxim gml respect overal result highlight identifi first time abil l rigida leaf extract modul inflammatori process data suggest leaf extract plant potenti develop herbal formul treatment inflamm | D045469 | T002 |
36,234,828 | electrocatalyt depolymer self immol poli dithiothreitol deriv report use electrogener anthraquinon radic anion aq trigger fast catalyt depolymer polym deriv poli dithiothreitol pdtt self immol polym sip backbon dithiothreitol connect disulfid bond end cap via disulfid bond pyridyl group pdtt deriv studi includ polym simpl thiohexyl end cap modifi aq methyl group steglich esterif polym shown depolymer use catalyt amount electron deliv aq pdtt littl electron per polym chain need achiev complet depolymer hypothes reaction proceed aq electron carrier either molecular pendant group transfer electron disulfid bond polym dissoci manner generat thiyl radic thiolat rapid catalyt depolymer driven thiyl radic attack disulfid bond intern pdtt chain chain reaction electrochem trigger work general method initi depolymer pdtt deriv may like also use depolymer disulfid polym | D004220;D011108 | T104;T122 |
36,234,827 | respons adult hypera rumici l synthet plant volatil blend behavior respons hypera rumici l adult vari blend synthet plant volatil spvs various concentr lieu singl compound report first time studi rumex confertus plant treat two blend spvs differ quantiti act either attract repel insect blend b consist five green leaf volatil glvs name z hexen e hexen z hexenol e hexenol z hexen yl acet blend b contain six plant volatil name z ocimen linalool benzyl acet methyl salicyl caryophyllen e farnesen blend made avail four differ amount volatil correspond compound ad l hexan amount ng effect two blend differ concentr insect evalu use tube olfactomet sex insect found signific repel highest volatil level b two level b ng femal also observ repel use b ng volatil attract observ sex b three lower volatil level ng addit experi use attract unmat femal found attract male wherea mate femal attract b unmat mate male previous observ copula attract femal | D055549;D048889 | T109;T204 |
36,234,825 | anion contain tripoid conjug n system salt substitut amino triazolo c oxadiazol ium ide well synthesi structur thermal stabil strategi synthesi cyanoethyl x amino triazolo c oxadiazol ium ide x h ch ch cn cn b co et c start amino azido oxadiazol develop key step strategi intramolecular thermolyt cyclize azido group bis cyanoethyl triazen group remov cyanoethyl protect group amid c gave potassium salt correspond nitramid sodium salt cyano ethoxycarbonylamid structur thermal stabil synthes compound studi experiment use multinuclear nmr spectroscopi x ray crystallographi thermogravimetri differenti scan calorimetri | D009585;D012492 | T104;T131;T197 |
36,234,824 | simpl high throughput method analysi vicin convicin faba bean faba bean one earliest domest crop econom environment benefit like legum faba bean high protein use contribut balanc diet meat substitut howev also produc anti nutrit compound vicin convicin v c enzymat degrad reactiv aglycon potenti lead hemolyt anemia favism current method analysi use lc uv suitabl high concentr thus lack select sensit accur quantit low v c genotyp current develop develop fulli valid rapid high throughput lc ms method analysi v c faba bean optim extract protocol assess method linear limit detect limit quantit accuraci precis matrix effect method use time less start materi remov use buffer acid organ chemic improv precis accuraci compar current method | D005236;D031307 | T047;T002 |
36,234,823 | green extract process complex sampl veget matric coupl line detect system critic review detect analyt complex organ matric requir seri analyt step obtain reliabl analysi sampl prepar time consum prolong error prone step reduc reliabl investig review aim discuss advantag limit extract bioactiv compound sampl prepar techniqu autom coupl line detect review also evalu public topic longitudin bibliometr analysi appli statist mathemat method analyz trend perspect hot topic research area furthermor state art green extract techniqu complex sampl veget matric coupl analysi system present among extract techniqu liquid sampl solid phase extract common combin system scientif literatur contrast line extract system appli solid sampl supercrit fluid extract ultrasound assist extract microwav assist extract pressur liquid extract frequent green extract techniqu | D025924;D014675 | T059;T168 |
36,234,820 | analyz effect steam chemic constitu defec liver injuri polygonum multiflorum radix heshouwu multipl analysi techniqu combin multivari statist steam characterist pharmaceut skill tradit chines medicin tcm polygonum multiflorum radix pm steam product use asia centuri raw polygonum multiflorum radix rpm common use promot defec exert toxic especi liver injuri howev rpm made convert polygoni multiflori radix praeparata pmp steam consid good method reduc defec liver injuri caus pm asia chemic constitu tcm key action systemat analyz effect steam pm constitu defec liver injuri identifi main constitu pm pmp result show steam two constitu tsg catechin decreas six constitu procyanidin b b disappear four constitu emodin physcion increas emodin glucosid remain unchang pmp pharmacolog experi show pm could promot defec howev obvious effect respons pmp high dose pm day caus degre liver injuri although injuri disappear day drug withdraw network pharmacolog molecular dock studi show tsg emodin physcion effect promot defec caus liver injuri collect find show steam reduc effect pm promot defec reduc liver injuri tsg may one import constitu pm promot defec caus liver injuri | D002392;D004365;D004642;D000068676;D028502 | T121;T109;T123;T002 |
36,234,819 | molecular character bacteri isol soil sampl evalu antibacteri potenti mdrs soil microb divers inhabit biolog activ metabolit endospor format gave characterist predomin recognit among microbi communiti present studi collect ten soil sampl green land agricultur marshi soil site khyber pakhtunkhwa pakistan cultur describ media bacteri isol identifi phenotyp biochem phylogenet analysi phylogenet analysi reveal three bacteri isol show nucleotid sequenc similar brevibacillus formosus bacillus subtili paenibacillus dendritiformi crude extract prepar bacteri isol assess anti bacteri potenti various target multidrug resist strain mdrs includ acinetobact baumannii atcc methicillin resist staphylococcus aureus mrsa baa klebsiella pneumonia atcc pseudomona aeruginosa baa staphylococcus aureus atcc escherichia coli atcc salmonella typhi atcc analysi reveal bacteri extract possess activ gram negat gram posit bacteria concentr mgml effici restrict growth e coli compar posit control ciprofloxacin studi conclud identifi speci potenti produc antimicrobi compound use control differ microbi infect especi mdrs moreov analysi bacteri extract gc ms indic presenc differ antimicrobi compound propano acid oxal acid phenol hexadecano acid | D055624 | T007 |
36,234,818 | protect effect pollenaid plus soft gel capsul hydroalcohol extract isol prostat ovari expos lipopolysaccharid pollen extract repres innov approach manag clinic symptom relat prostat pelvic inflammatori diseas pid context aim present work analyz phenol composit hydroalcohol extract pollenaid plus soft gel capsul evalu extract cytotox effect human prostat cancer pc cell human ovari cancer ovcar cell addit protect effect investig isol prostat ovari specimen expos lipopolysaccharid lps phytochem investig identifi catechin chlorogen acid gentis acid hydroxytyrosol promin phenol extract exert relev cytotox effect pc ovcar cell howev extract show dose depend inhibit pro inflammatori il tnf gene express prostat ovari specimen extract effect prevent lps induc upregul cat sod gene express deepli involv tissu antioxid defens system final dock approach suggest capabl catechin chlorogen acid interact trpv receptor play master role prostat inflamm overal present find demonstr anti inflammatori antioxid effect formul thus suggest capabl manag clinic symptom relat prostat pid | D002392;D010051;D011472 | T121;T047;T109;T191 |
36,234,817 | polyphenol metabol diseas polyphenol pps larg group phytochem contain phenol ring two hydroxyl group possess power antioxid properti multipl therapeut effect possibl health benefit vivo vitro well report clinic studi consid free radic scaveng anti inflammatori properti substanc use treat differ kind condit associ metabol disord mani symptom metabol syndrom mts includ obes dyslipidemia atherosclerosi elev blood sugar acceler age liver intox hypertens well cancer neurodegen disord substanti reliev dietari pps present studi explor bioprotect properti associ under mechan pps detail understand natur compound open new opportun produc uniqu natur pp rich dietari medicin plan ultim affirm health benefit | D024821;D059808 | T121;T047;T109 |
36,234,816 | phenanthraquinon dope polymethyl methacryl photopolym holograph record phenanthraquinon dope polymethyl methacryl pqpmma photopolym consid promis holograph storag media due uniqu properti high stabil simpl prepar process low price volumetr shrinkag paper review develop process pqpmma photopolym incept present summar process look develop potenti pqpmma practic applic | D006696;D019904 | T060;T109;T122 |
36,234,814 | synthesi novel pyrazol deriv contain phenylpyridin moieti herbicid activ discov new compound favor herbicid activ rang phenylpyridin moieti contain pyrazol deriv design synthes identifi via nmr hrms herbicid activ six speci weed evalu greenhous via pre post emerg treatment g aihm bioassay reveal compound exhibit moder herbicid activ digitaria sanguinali abutilon theophrasti setaria viridi post emerg treatment instanc compound c demonstr inhibit activ setaria viridi slight superior pyroxasulfon thus compound c may serv new possibl lead compound discoveri post emerg herbicid | D006540 | T131 |
36,234,813 | renew schiff base ionic liquid lignocellulos biomass pretreat grow interest sustain sourc chemic energi renew reliabl sourc stimul design synthesi renew schiff base iminium ionic liquid il replac fossil deriv il studi report synthesi three uniqu iminium acet il lignin deriv aldehyd sustain futur lignocellulos biorefineri synthes il contain imin imin along amin structur il imin group exhibit better pretreat efficaci achiev gt sugar releas various analyt comput tool employ understand pretreat efficaci il first studi demonstr eas synthesi renew il therefor open door new class schiff base il investig could also design task specif | D052578;D008031 | T103;T109;T123;T120 |
36,234,812 | authent citrus spp cold press essenti oil oxygen heterocycl compon citrus essenti oil routin adulter lack regul reliabl authent method unfortun relat simpl chemic makeup tremend price variat among citrus varieti encourag interspeci adulter citrus oil studi sensit uplc msms method quantit coumarin furanocoumarin develop valid method appli screen essenti oil differ citrus speci studi knowledg repres comprehens investig coumarin furanocoumarin profil across commerci scale citrus oil date result show lowest amount detect calamansi oil express oil italian bergamot show highest furanocoumarin content highest level individu furanocoumarin bergamottin notabl differ observ coumarin furanocoumarin level among oil differ crop varieti origin within speci potenti correl observ bergapten xanthotoxin match known biosynthet pathway found pattern furanocoumarin profil line known variat among citrus ancestr taxa howev contrari literatur also detect xanthotoxin sweet orang member mandarin taxon use multivari analysi abl divid citrus oil main group correl coumarin composit | D002957;D011564;D009822 | T121;T109;T168;T002 |
36,234,811 | synthesi isomer benzazecin decor endocycl allen moieti exocycl conjug doubl bond evalu anticholinesteras activ transform methoxymethylethynyl substitut isoquinolin trigger termin alkyn alcohol studi new benzazecin contain compound synthes methoxymethyl benzazecin incorpor endocycl c c allen fragment yliden deriv methoxymethylen benzazecin reaction mechan investig preliminari vitro screen potenti inhibitori activ human acetyl butyrylcholinesteras ach bche monoamin oxidas b mao mao b show allen compound potent correspond yliden one select ach inhibitor among allen e r ch ome found competit ach inhibitor low micromolar inhibit constant valu k equipot correspond phenyl deriv n r ph k fold water solubl | D002800;D008996 | T121;T109 |
36,234,810 | develop novel disubstitut thiohydantoin analogu potent anti inflammatori activ vitro silico assess inflamm main caus sever autoimmun diseas includ type diabet rheumatoid arthriti bullous pemphigoid paraneoplast pemphigoid multipl sclerosi current urgent demand discoveri novel anti inflammatori drug potent activ also safe long term applic toward aim present studi report design synthesi character set novel disubstitut thiohydantoin deriv anti inflammatori activ synthes compound assess murin leukemia cell line raw evalu cytotox activ potenc prevent nitric oxid product result reveal synthes compound possess consider cytotox activ togeth abil reduc product murin leukemia cell line raw among synthes compound compound exhibit potent cytotox activ ic gml compar celecoxib drug ic valu gml demonstr signific abil diminish product six fold reduct explor mode action respons anti inflammatori activ reveal compound display signific dose depend inhibitori effect express pro inflammatori cytokin il furthermor compound demonstr abil signific reduc express inflammatori cytokin il tnf gml compar celecoxib final detail molecular model studi indic compound exhibit substanti bind affin toward bind pocket cyclooxygenas enzym taken togeth studi reveal disubstitut thiohydantoin could consid promis scaffold develop potent anti inflammatori agent | D007938;D013867 | T191;T109 |
36,234,809 | broadband multidimension spectroscopi identifi amid ii vibrat silkworm film use two dimension infrar spectroscopi disentangl broad infrar band amid ii vibrat region bombyx mori nativ silk film identifi singl amid ii mode correl specif secondari structur amid amid ii mode strong vibrat coupl manifest cross peak infrar spectra frequenc determin amid amid ii frequenc secondari structur cross referenc well known amid assign determin amid ii n h absorb around cm helic sheet structur respect also observ peak cm could easili assign amid ii mode instead tentat assign tyrosin sidechain result stand contrast previous find linear infrar spectroscopi highlight abil multidimension spectroscopi untangl convolut spectra suggest need caution assign silk amid ii spectra | D012831 | T204 |
36,234,807 | first discoveri cholesterol lower activ parthenolid npcl inhibitor elev cholesterol signific increas risk develop atherosclerosi coronari heart diseas key treat hypercholesterolemia lower plasma cholesterol level studi cholesterol lower potenti parthenolid ptl natur occur small molecul tanacetum parthenium first put forth ptl cholesterol lower abil inhibit cellular uptak cholesterol dose depend manner perform par posit control drug ezetimib niemann pick c like npcl identifi potenti therapeut target hypercholesterolemia interact ptl npcl could explain result molecular dock filipin stain reinforc hypothesi furthermor ptl reduc express npcl hepg cell concentr depend manner suggest ptl function potenti npcl inhibitor therapeut potenti hypercholesterolemia | D000924;D006937;D006949 | T121;T047;T033 |
36,234,806 | simultan preconcentr triazol fungicid residu use situ coacerv extract base doubl solvent supramolecular system prior high perform liquid chromatograph analysi situ coacerv extract cae base doubl solvent supramolecular system coupl liquid liquid microextract investig extract enrich triazol fungicid format doubl solvent supramolecular system generat situ format use extract solvent coacerv extract method dispers solvent requir new doubl solvent supramolecular system higher extract abil compon alon differ factor could affect extract capabl studi optim includ type doubl extract volum salt addit vortex time centrifug time optimum extract condit method provid high enrich factor ef low limit detect lod g l limit quantit loq g l addit propos method prosper appli determin triazol fungicid water fruit juic soy milk sampl | D005659;D059627 | T059;T131 |
36,234,805 | c nmr chemic shift benzazol tautomer ratio criterion benzimidazol import heterocycl fragment present mani biolog activ compound great varieti therapeut purpos benzimidazol activ explain exist tautomer equilibrium bind affin tautom protein target depend establish bioactiv conform effect tautom ligand protein bind mechan determin work search analyz seri report c nmr spectra benzazol benzazolidin thion purpos estim tautomer equilibrium herein sever approach determin problem present make good initi introduct non expert reader chemic shift differ cc signal benzimidazolidin thion methyl thiomethylbenzimidazol refer use work quantit calcul solut pyrrol pyridin tautomer ratio equilibrium analysi help research correct assign chemic shift benzimidazol calcul intracycl exocycl tautomer ratio well mesomer proport benzimidazol | D001562;D013871 | T109 |
36,234,804 | small molecul enhanc precis safeti genom edit cluster regular interspac short palindrom repeat crispr base genom edit technolog revolution biolog biotechnolog medicin spur develop new therapeut modal howev remain sever barrier safe use crispr technolog unintend target dna cleavag small molecul import resourc solv problem given facil deliveri fast action enabl tempor control crispr system provid comprehens overview small molecul precis modul crispr associ cas nucleas guid rnas grnas also discuss small molecul control emerg genom editor eg base editor anti crispr protein molecul could use precis investig biolog system develop safer therapeut modal | D064113;D000072669 | T063;T040 |
36,234,803 | adenosin receptor antagonist improv cognit impair inhibit neuroinflamm excitatori neurotox chronic periodont mice adenosin receptor antagonist sch report anti inflammatori effect howev role chronic periodont cp induc cognit impair associ porphyromona gingivali lipopolysaccharid p gingivali lps remain unclear studi investig role sch mice cp induc cognit impair cblj mice use develop cp model inject mgkg p gingivali lps palat gingiv sulcus maxillari first molar twice week four week mice divid control p gingivali lps p lps p lps sch sch group passiv avoid test pat morri water maze mwm use assess cognit mice furthermor cdadenosin neuroinflamm glutam transport glutam assess compar p lps group mgkg sch increas latenc decreas error time pat increas platform cross number mwm sch inhibit microgli activ decreas pro inflammatori cytokin glutam level increas glt psd express hippocampus first report sch treatment cp induc cognit impair may relat anti inflammatori activ anti glutam excitatori neurotox suggest sch use novel agent treat cognit impair | D055113;D060825;D020258 | T047;T037;T048 |
36,234,802 | isol molecular identif amino acid profil singl cell protein produc phototroph bacteria isol oil contamin soil sampl current studi soil sampl gather differ place petrol diesel fill station locat isol photosynthet bacteria anaerob condit use paraffin wax overlay pour plate method biebl pfennig medium three isol strain name rhodopseudomona palustri smr mallapur rhodopseudomona palustri nr mppr nacahram rhodopseudomona faecali n raju mppr karolbagh morpholog bacteria examin scan electron microscop sem phylogenet relationship r palustri strain examin mean rrna gene sequenc analysi use ncbi blast search phylogenet tree sequenc data r palustri deposit nation centr biotechnolog research ncbi total amino acid produc isol bacteria determin hplc total amino acid deriv produc r palustri smr strain among carnosin found highest concentr ngml follow isoleucin ngml anserin ngml r palustri nr mppr found produc amino acid thirteen amino acid deriv found produc r faecali n raju mppr concentr carnosin ngml found highest follow isoleucin ngml anserin ngml microb explor scale process along biohydrogen singl cell protein product | D000596;D002336 | T121;T109;T123;T116 |
36,234,801 | structur character cis tran pt nh cl conjug chitosan nanoparticl conjug chitosan kd anticanc drug cis tran pt nh cl abbrevi cis pt tran pt studi ph use multipl spectroscop method thermodynam analysi character natur drug chitosan interact potenti applic chitosan nanoparticl drug deliveri analysi show hydrophob hydrophil contact involv drug polym interact chitosan size charg play major role stabil drug polym complex overal bind constant k ch cis pt k ch cis pt k ch tran pt k ch tran pt stabl complex form cis pt tran pt chitosan adduct stronger bind observ chitosan comparison chitosan kd studi indic polym chitosan stronger drug carrier chitosan kd vitro | D000970;D048271;D053758 | T121;T109;T073 |
36,234,800 | polyphenol composit antioxid antiprolif antidiabet activ coronopus didymus leaf extract coronopus didymus brassicacea common known lesser swine cress report use pharmacolog activ studi aim evalu medicin potenti c didymus extract cancer diabet infecti bacteria oxid stress identif bioactiv compound present extract effect use differ solvent extract c didymus content major polyphenol biolog activ investig plant sampl shade dri ground fine powder soak pure aceton ethanol methanol highest content major polyphenol found methanol base extract ie chlorogen acid hb acid kaempferol ferul acid quercetin benzoic acid mgg dri weight respect follow ethanol aceton base extract methanol base extract also result highest antioxid activ wherea highest antiprolif alpha glucosidas inhabit demonstr ethanol base extract antibacteri properti c didymus observ test strain bacteria studi focus identif specif bioactiv compound respons pharmacolog activ | D019607;D029686 | T002 |
36,234,799 | fast non destruct profil commerci coffe aroma three condit bean powder brew use gc im flavor coffe affect prepar paramet investig flavor profil three coffe brand three condit bean powder brew analyz gas chromatographi ion mobil spectrometri gc im electron nose e nose flavor result studi use multipl factor analysi mfa total peak identifi coffe sampl gc im princip compon analysi pca show coffe sampl could group separ total volatil organ compound voc select biomark distinguish coffe sampl includ aldehyd keton alcohol acid ester furan compound comparison e nose gc im data use partial least squar regress plsr mfa show gc im could present close sampl space compar e nose gc im could use classifi coffe sampl short time also provid voc bio marker discrimin coffe sampl | D009812;D055549 | T109;T120;T070 |
36,234,798 | adsorpt photocatalyt degrad pesticid nanocomposit review extens use pesticid agricultur signific impact environ human health pollut inadequ dispos water bodi addit pesticid caus advers effect human aquat anim due incomplet remov aqueous medium convent wastewat treatment therefor process heterogen photocatalysi adsorpt nanocomposit receiv special attent scientif communiti due uniqu properti abil degrad remov sever organ pollut includ pesticid report review use nanocomposit pesticid adsorpt photocatalyt degrad aqueous solut bibliograph search perform use sciencedirect american chemic societi ac royal societi chemistri rsc index use boolean logic follow descriptor pesticid degrad photocatalysi nanocomposit nanocomposit pesticid adsorpt search limit research articl document last ten year januari june result made possibl verifi danger pesticid common degradedremov wastewat time potenti support nanocatalyst nanoadsorb decontamin wastewat contain pesticid confirm present reduc bandgap energi occur wide rang wavelength moreov due great affin support nanocatalyst pesticid better charg separ high remov degrad valu report organ compound thus class nanocomposit investig work magnet character suitabl nanomateri potenti uniqu properti use heterogen photocatalyst adsorpt pesticid | D053761;D010575;D014874 | T131;T073 |
36,234,797 | assess qualiti burkina faso soybean base fatti acid composit pesticid residu contamin soybean wide use food industri high fatti acid protein content howev increas use pesticid control pest cultiv addit public health concern may influenc nutrit qualiti soybean studi aim assess nutrit qualiti soybean respect fatti acid profil pesticid residu contamin level fatti acid pesticid soybean varieti g g determin gas chromatographi quecher method respect result show signific variat quantit qualit fatti acid composit two varieti g g fatti acid detect g varieti g g fatti acid g varieti respect addit activ pesticid compound found among imazalil quintozen cyfluthrin lindan exceed maximum limit g varieti better nutrit profil compar g profil fatti acid content pesticid residu use import determin soybean util human nutrit | D010573;D010575 | T131 |
36,234,796 | water solubl leggero pillar aren studi aqueous phase molecular recognit artifici receptor one frontier supramolecular chemistri sinc biochem process reaction take place aqueous medium heavili reli work water solubl version leggero pillar aren bear eight posit charg pyridinium moieti cwp l design synthes exhibit good bind affin certain aliphat sulfon speci aqueous solut signific control experi demonstr guest bind perform cwp l superior counterpart water solubl macrocycl receptor tradit pillararen | D047250;D062165 | T121;T109;T192 |
36,234,795 | shionon target pneumolysin amelior acut lung injuri induc streptococcus pneumonia vivo vitro streptococcus pneumonia pneumonia gram posit bacterium caus sever bacteri pneumonia result high morbid mortal infect peopl meanwhil isol drug resist pneumonia grow rais concern strategi combat pneumonia infect disturb pneumonia pathogen drug resist develop novel anti infect strategi compound urgent studi anti infect effect shionon explor minimum inhibitori concentr mic assay growth curv determin perform evalu effect tetracycl triterpenoid compound shionon pneumonia hemolysi test western blot oligomer inhibit assay molecular dock carri explor anti infect mechan shionon moreov protect effect shionon also confirm mousepneumonia model result show excel hemolyt inhibitori activ shionon observ less gml meanwhil shionon could disturb oligomer pneumolysin pli interfer pli express less gml molecular dock suggest shionon target asp ile thr phe asn amino acid site reduc pneumonia pathogen furthermor shionon allevi lung histopatholog injuri decreas lung bacteri colon vivo result show shionon could bind pli activ pocket concentr gml neutral pli hemolysi activ reduc pneumonia pathogen vitro vivo | D055371;D014315 | T109;T037 |
36,234,794 | site specif radioiodin oligonucleotid phenol element programm approach radioiodin oligonucleotid provid extra modal nucleic acid base theranost potenti applic herein report design synthesi phosphoramidit embed phenol moieti demonstr oligonucleotid readili function phenol precursor general dna synthesi identifi introduct precursor block specif aptam radioiodin applic dna rna oligonucleotid site specif approach commerci kit | D009696;D009841 | T123;T114 |
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