PMID int64 35.7M 36.4M | Title/Abstract stringlengths 22 8.78k | MeshTerms stringlengths 7 101 | SemanticTypes stringlengths 4 64 |
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36,229,876 | predict model breast cancer relat lymphedema systemat review critic apprais develop risk predict model breast cancer lymphedema increas studi focus qualiti model applic therefor studi aim systemat review critic evalu predict model develop predict breast cancer relat lymphedema | D000072656;D001943;D008209 | T191;T047;T046 |
36,229,875 | sphingosin phosphat receptor mediat earli stage pancreat system inflammatori respons via nf kappa b activ acut pancreat acut pancreat activ inflammatori signal includ nuclear factor kappa b nf b pathway within acinar cell known earli intracellular event occur parallel patholog trypsinogen activ sphingosin phosphat receptor spr play critic role endotheli inflamm previous studi report spr defici signific reduc inflammatori respons liver injuri cholestasi condit howev role spr inflammatori signal activ within acinar cell inflammatori respons acut pancreat elucid report spr upregul whole pancrea acut pancreat blockad spr pharmacolog inhibit spr jte aav mediat knockdown spr improv sever pancreat injuri indic signific reduct inflamm acinar cell death acut pancreat mice moreov spr predomin sprs express pancreat acinar cell mediat nf b activ earli inflammatori respons within acinar cell acut pancreat condit via rock signal pathway extracellular signal regul kinas pathway p mitogen activ protein kinas pathway addit spr mediat macrophag nf b activ migrat polar toward phenotyp therefor result demonstr spr mediat earli inflammatori respons acinar cell promot progress acut pancreat success link local event systemat inflammatori respons lead novel therapeut target acut pancreat aim halt progress inflammatori respons video abstract | D016328;D010195 | T047;T046;T116;T129 |
36,229,873 | neomorph dna bind enabl tumor specif therapeut gene express fusion addict childhood sarcoma chimer fusion transcript factor oncogen hallmark sever devast cancer entiti includ pediatr sarcoma ewe sarcoma ew alveolar rhabdomyosarcoma arm despit exquisit specif driver oncogen consid larg undrugg due lack enzymat activityher show ew model capit neomorph dna bind prefer addict respect fusion transcript factor ewsr fli leverag express therapeut genesw genet engin de novo enhanc base synthet high potent express cassett elicit ewsr fli depend express therapeut payload evidenc episom crispr edit genom report assay combin silico screen immunohistochemistri identifi gpr high specif cell surfac antigen target transduct strategi ew function experi demonstr anti gpr pseudotyp lentivirus harbor express cassett specif transduc ew cell promot express viral thymidin kinas sensit ew treatment otherwis relat non toxic val ganciclovir lead strong anti tumorigen advers effect vivo prove similar vector design appli pax foxo driven arm express immunomodulatori cytokin il xcl tumor entiti typic consid immunolog coldcollect result generat pediatr sarcoma indic exploit rather suppress neomorph function chimer transcript factor may open inroad innov person therapi high versatil approach may translat cancer addict oncogen transcript factor uniqu dna bind properti | D012509;D012512 | T191 |
36,229,872 | comput phenotyp obstruct airway diseas protocol systemat review last decad comput scienc contribut immens character phenotyp airway diseas difficult compar deriv phenotyp across studi perhap result differ decis fed phenotyp exercis aim perform systemat review studi use comput approach phenotyp obstruct airway diseas children adult | D001249;D029424 | T047 |
36,229,871 | evalu biofilm format acryl resin use fabric dental temporari restor use print technolog temporari implant retain restor requir support function esthet masticatori system final restor complet deliv acryl resin common use prosthet dentistri late use three dimension print technolog sinc technolog fair new number studi suscept microbi adhes low restor place even short period time may becom reservoir microorgan may affect peri implant tissu trigger inflamm endang procedur aim studi test biofilm format acrylamid resin use fabric temporari restor print technolog assess post process impact microbi adhes | D000180;D005840 | T121;T109;T130;T122 |
36,229,869 | health relat qualiti life mental health famili children adolesc affect rare diseas high diseas burden perspect affect children sibl advanc genet pharmaceut technolog pediatr care enabl treatment option increas number rare diseas affect children howev current treatment option primarili palliat natur health relat qualiti life hrqol mental health impair popul sibl increas import among children adolesc rare diseas technolog depend carri high diseas burden select target popul studi cross section observ design children hrqol assess disabkid dcgm well kidscreen mental health assess strength difficulti questionnair sdq affect children parent sibl | D008603;D011788 | T078;T041 |
36,229,868 | comorbid phenotyp risk mortal patient osteoarthr uk latent class analysi osteoarthr oa common chronic condit associ chronic condit mortal larg unknown studi aim use latent class analysi lca comorbid patient oa match control without oa identifi cluster comorbid examin associ cluster opioid use mortal | D000701;D020370 | T121;T047;T109;T131 |
36,229,867 | role educ level chang endors medic treatment perceiv public stigma toward psychosi hong kong comparison three popul base survey studi aim investig chang perceiv public stigma pps toward psychosi endors medic treatment hong kong chines populationth role educ level chang pps endors medic treatment psychosi also examin | D011618;D057545 | T048;T033 |
36,229,865 | cardiac target piasi gene silenc mediat desumoyl caveolin prevent ischemiareperfus induc na v downregul ventricular arrhythmia abnorm myocardi na v express function caus lethal ventricular arrhythmia myocardi ischemia reperfus ir protein inhibitor activ stat piasi mediat caveolin cav sumo modif affect cav bind voltag gate sodium channel na v piasi activ increas myocardi ir unclear whether attribut plasma membran na v downregul ventricular arrhythmia | D000889;D051244 | T121;T116;T192 |
36,229,862 | molecular insight heat shock protein human parasit blood fluke schistosoma mansoni heat shock protein hsps evolutionarili conserv protein produc cell respons hostil environment condit vital organ homeostasi undertook first detail molecular bioinformat analysi import protein map tissu express human parasit blood fluke schistosoma mansoni one causat agent neglect tropic diseas human schistosomiasi | D010271;D012550 | T204 |
36,229,861 | impact cardiovascular risk diagnost accuraci ultrasound halo score giant cell arter evalu impact cardiovascular risk cvr diagnost accuraci ultrasonograph us halo score patient suspect giant cell arter gca | D002318;D013700 | T047 |
36,229,860 | period still occur continu drug deliveri parkinson diseas continu drug deliveri cdd use moder advanc late stage parkinson diseas pd control motor non motor fluctuat period transderm rotigotin indic earli fluctuat subcutan apomorphin infus levodopa carbidopa intestin gel utilis advanc pd three strategi consid exampl continu dopaminerg stimul achiev cdd central premis cdd achiev stabl control parkinsonian motor non motor state avoid emerg period howev data suggest despit efficaci reduc number durat period strategi still prevent period middl late stage pd thus contradict wide held concept continu drug deliveri continu dopaminerg stimul emerg period still occur unknown review analys potenti reason persist contribut drug devic relat involv problem relat site specif drug deliveri analys propos chang dopaminerg non dopaminerg mechan basal ganglia might render persist period unrespons dopaminerg therapi deliv via cdd | D002230;D010300 | T121;T047;T109 |
36,229,859 | ten area icu clinician awar help retain nurs icu shortag nurs icu new phenomenon exacerb covid pandem under reason relat well recogn includ excess workload moral distress percept inappropri care lead burnout increas intent leav set vicious circl wherebi fewer nurs result increas pressur stress remain nurs shortag impact patient care qualiti work life icu staff effort made manag nurs leader icu clinician understand amelior factor lead nurs leav highlight broad area icu clinician awar may improv qualiti work life thus potenti help critic care nurs retent | D002055;D009726;D009741;D010820 | T097;T048 |
36,229,858 | two case spindl cell tumor cd co express show novel raf fusion recent novel group cd co express spindl cell tumor distinct stromal perivascular hyalin harbor recurr gene fusion involv ret raf braf ntrk gene identifi | D048493;D012983 | T191;T126;T116 |
36,229,856 | pge promot macrophag recruit neovascular murin wet type amd model age relat macular degener amd progress chronic diseas central retina lead caus blind worldwid activ macrophag recruit injur eye great contribut pathogenesi choroid neovascular cnv exud amd wet amd studi describ effect cyclooxygenas cox prostaglandin e pge signal macrophag activ cnv format wet amd mous model laser induc wet amd mice receiv intravitr inject celecoxib select cox inhibitor optic coher tomographi oct fundus fluorescein angiographi ffa choroid histolog cnv lesion biochem marker assess level pge express high laser induc cnv lesion macrophag recruit cnv develop signific less celecoxib treatment e prostanoid receptor ep r protein kinas c pkc signal involv macrophag activ interleukin il product bone marrow deriv macrophag bmdms vitro addit il found induc prolifer migrat human choroid microvascular endotheli cell hcec thus pge ep r signal network serv potenti therapeut target cnv wet type amd video abstract | D020256;D016753 | T046;T116;T129 |
36,229,855 | dna methyl signatur vascular differenti gene aberr vessel human cerebr arterioven malform nidus arterioven malform avm tangl arteri vein ruptur result catastroph hemorrhag vulner site brain cerebr avm associ high mortal rate human causat factor stimulus arteri venous junction molecular basi develop progress cerebr avm remain unknown known aberr hemodynam forc arteri vein junction contribut develop avm mechanist pathway unclear given various environment stimuli modul epigenet modif chromatin cell specul misregul dna methylom could lead cerebr avm develop identifi aberr epigenet signatur use avm nidus tissu analyz global dna methylom use infinium dna methylom array observ signific alter dna methyl gene associ vascular development pathway valid dna hypermethyl dna bisulfit sequenc analysi select gene human cerebr avm nidus taken togeth provid first experiment evid aberr epigenet signatur gene vascular develop pathway human cerebr avm nidus | D019175;D002538 | T044;T019 |
36,229,854 | arida defici revers respons anti pd l therapi egfr mutant lung adenocarcinoma enhanc autophagi inhibit type interferon product egfr mutat non small cell lung cancer nsclc associ poor respons immun checkpoint inhibitor ici nsclc patient harbor egfr mutat benefit immunotherapi novel biomark therapeut need predict nsclc prognosi enhanc efficaci ici nsclc patient harbor egfr mutat especi lung adenocarcinoma luad patient account approxim nsclc case | D000077192;D002289;D007370;D008175 | T191;T121;T116;T129 |
36,229,853 | overcom high level adenosin mediat immunosuppress dzd potent select aar antagonist adenosin potent immunosuppress whose level tumor microenviron tme often much higher normal tissu bind adenosin receptor aar activ cascad gene lead immunosuppress addit immun checkpoint blockag mark increas aar express cell could dampen anti tumor respons sever aar antagonist clinic develop limit clinic benefit report far aar antagonist show much diminish activ high adenosin level found tme may explain clinic underperform report discoveri earli clinic develop dzd novel aar antagonist fulli block aar mediat immunosuppress common found tme adenosin stimul phosphoryl cyclic amp respons element bind protein creb cell inhibit anti tumor cytokin secret pbmcs dose depend manner dzd abl revers immunosuppress induc high concentr adenosin demonstr inhibit creb phosphoryl cell restor th cytokin secret pbmcs stimul dendrit cell dcs matur singl agent dzd show anti tumor growth multipl syngen mous tumor model profound anti tumor effect observ dzd combin immun checkpoint inhibitor radiotherapi chemotherapi good pkpd relationship observ anim model phase clinic studi downregul pcreb detect human cell consist preclin predict data support clinic develop dzd patient cancer | D000241;D009369 | T121;T191;T109;T123;T114 |
36,229,851 | sleep postur monitor base capacit coupl electrod deep recurr neural network capacit coupl electrod cc electrod non contact unobtrus technolog measur physiolog signal wide appli sleep monitor scenario common implement capacit electrocardiogram cecg could provid use clinic inform assess cardiac function detect cardiovascular diseas current studi sought explor anoth potenti applic cecg sleep monitor ie sleep postur recognit | D011187;D012890 | T040;T033 |
36,229,849 | evalu hybrid automat plan solut rectal cancer script base plan knowledg base plan two kind automat plan solut hybrid automat plan may integr advantag solut provid robust automat plan solut clinic studi evalu compar commerci avail hybrid plan solut manual plan script base plan | D050397;D012004 | T191;T061 |
36,229,848 | nationwid molecular survey dirofilaria immiti dirofilaria repen companion dog cat unit state america heartworm dirofilaria immiti known widespread dog cat usa countri wide preval studi perform date also larg scale studi determin whether close relat speci dirofilaria repen occur usa | D002371;D004183;D060348;D004184;D004283 | T047;T204 |
36,229,847 | classif accuraci blood base neurophysiolog marker differenti diagnosi alzheim diseas frontotempor lobar degener last decad non invas blood base neurophysiolog biomark shown great potenti discrimin sever neurodegen disord howev clinic workup patient cognit impair high unlik biomark achiev highest potenti predict accuraci owe multifactori natur alzheim diseas ad frontotempor lobar degener ftld | D000544;D057180;D057174 | T047;T048 |
36,229,844 | laparoscop versus open emerg colectomi ischem coliti propens score match comparison laparoscop colectomi rare perform ischem coliti aim propens score match studi compar preoper characterist intraop detail short term outcom emerg laparoscop colectomi versus tradit open approach patient ischem coliti | D017091;D010535 | T061;T047;T060 |
36,229,843 | associ adult onset still diseas collaps glomerulopathi case report collaps glomerulopathi character mark hypertrophi hyperplasia podocyt eventu collaps glomerular tuft import caus end stage renal diseas among mani caus collaps glomerulopathi autoimmun diseas system lupus erythematosus implic also rare report adult onset still diseas autoinflammatori condit character fever rash inflammatori arthriti associ collaps glomerulopathi | D007674;D007676;D016706 | T047 |
36,229,842 | ctpathway crosstalk base pathway enrich analysi method cancer research pathway enrich analysi pea common method explor function hundr gene identifi diseas risk pathway moreov differ pathway exert function crosstalk howev exist pea method suffici integr essenti pathway featur includ pathway crosstalk molecular interact network topolog result mani risk pathway remain uninvestig | D009369;D015398 | T191;T043;T044 |
36,229,841 | overal surviv individu metastat cancer sweden nationwid studi consist improv overal surviv os report individu metastat cancer swedish popul base regist allow nation coverag long follow time aim studi estim explor long term os individu diagnos metastat cancer use swedish nationwid health regist | D009369;D016609 | T191 |
36,229,840 | uterin choriocarcinoma aris serous carcinoma postmenopaus woman analysi next generat sequenc pd l immunochemistri uterin somat choriocarcinoma rare clinic aggress malign tumor frequent concur cancer howev molecular pathogenesi somat choriocarcinoma concurr carcinoma rare address date | D002277;D002822;D018284 | T191 |
36,229,839 | fatti liver index predictor incid type diabet communiti dwell adult longitudin find year diagnos fatti liver identifi diseas status import fatti liver relat diseas prevent fatti liver index fli easili avail clinic practic use manag fatti liver prevent relat diseas larg scale long term follow prospect studi investig relationship fli incid type diabet tdm independ baselin insulin resist status therefor studi aim evalu associ fli incid tdm determin whether fli could use indic tdm use larg sampl communiti base korean cohort year | D003924;D005234 | T047 |
36,229,838 | foxd depend rala anxa src complex promot ctc format breast cancer earli metastasi key factor contribut poor breast cancer bc prognosi circul tumor cell ctcs regard precursor cell metastasi ultim respons main caus death bc howev date molecular mechan under ctc format bc insuffici defin | D017306;D001943;D009360 | T191;T025;T123;T116 |
36,229,837 | sex differ patient recoveri follow acut achill tendon ruptur larg cohort studi incid achill tendon ruptur atr increas past decad treatment may individualis base upon multipl factor includ age pre injuri activ level separ ruptur tendon end sever studi indic women may poorer self report clinic outcom compar men number women studi often small due differ incid atr gender | D000125;D016512;D013708 | T023;T037 |
36,229,836 | type densiti healthi food outlet univers foodscap geograph map characteris food resourc ghanaian univers campus food environ view interfac individu interact wider food system procur andor consum food institut food environ characterist associ health outcom includ obes nutrit relat non communic diseas nr ncds studi high incom countri object studi map characteris food outlet within ghanaian univers campus assess healthi food outlet | D005523;D000073296 | T047;T081 |
36,229,835 | explor biomed knowledg recurr glioblastoma use natur languag process deep learn model effici explor knowledg treatment recurr glioblastoma gbm critic clinician research howev due larg number clinic trial publish articl search knowledg labor intens current studi use natur languag process nlp analyz medic research corpora relat recurr glioblastoma find potenti target treatment | D000077321;D005909 | T191;T066 |
36,229,834 | pm air pollut co exposur temperatur effect modif pre matur mortal advanc age longitudin cohort studi china discours whether air pollut mixtur air pollut compon causal link increas mortal particular uncertainti whether associ mortal independ fine particul matter pm furthermor effect modif temperatur air pollut relat mortal also need evid | D000393;D000397 | T069;T131;T080 |
36,229,832 | combin deep sequenc convent molecular approach reveal broad divers distribut flea bartonella rodent shrew arctic subarct ecosystem bartonella intracellular bacteria transmit via anim scratch bite hematophag arthropod rodent associ flea play key role mainten bartonella worldwid speci identifi rodent host studi address occurr divers bartonella speci vector small mammal arctic subarct ecosystem increas impact invas speci climat chang | D001473;D001474;D058267;D005423 | T007;T047;T204 |
36,229,831 | pattern use advers event report among person regular inject buprenorphin systemat review given ongo opioid crisi novel intervent treat sever opioid use disord oud urgent need inject opioid agonist therapi ioat diacetylmorphin hydromorphon effect treatment sever treatment refractori oud howev barrier implement persist intraven buprenorphin treatment oud bup ioat sever possibl advantag tradit ioat includ safeti profil might enabl take home dose aim character inject practic among real world popul person regular inject buprenorphin well associ advers event report order inform possibl futur bup ioat intervent | D002047;D009293 | T121;T109;T048 |
36,229,830 | scope review unassist physic exam conduct synchron audio video telemedicin scope review aim provid broad overview research unassist virtual physic exam perform synchron audio video telemedicin identifi gap knowledg guid futur research | D017216 | T058 |
36,229,826 | risk factor delay hemorrhag ligasur hemorrhoidectomi one popular method treat hemorrhoid diseas hemorrhoidectomi ligasur devic proven less postop pain gain popular among surgeon howev previous studi found higher incid delay post hemorrhoidectomi bleed dphb patient underw ligasur hemorrhoidectomi compar underw tradit ferguson method follow studi aim reveal relationship dphb surgeon experi | D061865;D006484 | T061;T047 |
36,229,825 | deep brain stimul neurolog disord protocol systemat review meta analysi trial sequenti analysi randomis clinic trial deep brain stimul use sinc neurolog disord usa europ approv parkinson diseas essenti tremor dystonia epilepsi previous review assess effect deep brain stimul differ neurolog disord review methodolog limit | D046690;D004421;D020329;D010300 | T061;T047;T184 |
36,229,824 | interplay transcript factor mrtf matrix stiff control mammari acinar structur protrus format ongo differenti process character mammari gland sexual develop reproduct contrast defect remodel assum causal breast tumorigenesi shown recent myocardin relat transcript factor mrtf essenti form regular hollow acinar structur moreov mrtf activ known depend biochem physic properti surround extracellular matrix studi analys mutual interact differ matrix stiff mrtf activ format mainten mammari acini | D042361 | T023;T024 |
36,229,823 | postop clinic function outcom patient tumor tumor like lesion foot ankl tumor tumor like lesion foot ankl relat rare postop clinic outcom well report | D001859;D012983 | T191 |
36,229,822 | implement standard surgic techniqu robot assist restor rectal cancer resect singl center cohort studi despit increas focus technic perform total mesorect excis recent decad anastomot leakag al continu serious complic mani patient even hand experienc surgic team studi describ implement standard surgic techniqu effort reduc variabl decreas risk anastomot leakag improv associ short term outcom rectal cancer patient undergo robot assist restor rectal resect rrr | D012004;D012371 | T191;T090 |
36,229,820 | design principl fulli onlin flip learn health profess educ systemat review research covid pandem covid pandem instructor transit cours fulli onlin environ adopt flip learn context review examin challeng fulli onlin flip learn identifi use cours design element practic instruct approach health profess educ | D000086382;D020375 | T047;T067;T065 |
36,229,819 | comparison vivo hindfoot joint motion chang stanc phase non flatfoot stage ii adult acquir flatfoot compar kinemat characterist hindfoot joint stage ii adult acquir flatfoot deform aafd non flatfoot registr technolog singl fluoroscop imag system | D005413;D013628 | T023;T190;T019 |
36,229,818 | stakehold analysi covid manag control case iran covid pandem multi facet phenomenon mani polit econom social consequ success manag control pandem depend coordin effort mani organ institut therefor studi aim identifi analyz actor stakehold relat manag control pandem iran | D000086382 | T047;T067 |
36,229,816 | non invas assess hfpef mous model current gap futur direct heart failur hf preserv eject fraction hfpef preval increas larg clinic trial fail reduc mortal major reason outcom failur translat result basic research clinic evalu hfpef mous model requir assess three major key featur defin complex syndrom presenc preserv left ventricular eject fraction lvef diastol dysfunct develop hf addit hfpef associ multipl comorbid system arteri hypertens chronic obstruct pulmonari diseas sleep apnea diabet obes thus non cardiac disord assess crucial complet phenotyp character non invas procedur present unquestion advantag maintain anim welfar enabl longitudin analys howev unequivoc determin presenc hfpef use method remain challeng | D006333;D016277 | T042;T047;T046 |
36,229,815 | public belief consequ live obes republ ireland northern ireland studi aim captur public belief live obes examin belief chang time explor whether certain characterist associ nation repres sampl adult republ ireland roi northern ireland ni | D009765;D050177 | T047;T033 |
36,229,814 | risk thyroid dysfunct associ mrna inactiv covid vaccin popul base studi million vaccin recipi view accumul case report thyroid dysfunct follow covid vaccin evalu risk incid thyroid dysfunct follow inactiv coronavac mrna bntb covid vaccin use popul base dataset | D000086382;D000086663;D006980;D007037 | T047;T200;T067 |
36,229,813 | reproduct endocrin effect artemisinin piperaquin artemisinin piperaquin combin rat recommend artemisinin base combin regimen uncompl plasmodium falciparum malaria one combin artemisinin piperaquin tablet atq atq outstand advantag anti malari good efficaci fewer side effect easi promot applic depriv region howev data reproduct endocrin toxic atq remain insuffici thus assess potenti effect atq individu compon artemisinin art piperaquin pq reproduct endocrin system wistar rat | D000962;D037621;D006940 | T121;T047;T109;T046 |
36,229,811 | cistanch tubulosa phenylethanoid glycosid suppress adipogenesi l adipocyt improv obes insulin resist high fat diet induc obes mice cistanch tubulosa edit medicin tradit chines herb phenylethanoid glycosid major compon shown various benefici effect anti tumor anti oxid neuroprotect activ howev anti obes effect c tubulosa phenylethanoid glycosid ctpg regulatori effect gut microbiota still unclear present studi investig anti obes effect regulatori effect gut microbiota l cell model obes mous model | D031671;D007333;D061385 | T121;T046;T002 |
36,229,810 | healthcar utilis among patient stress induc exhaust disord treat multimod rehabilit programm longitudin observ studi stress induc exhaust disord major challeng swedish work life despit increas preval still limit knowledg effect differ rehabilit method studi aim describ healthcar utilis patient stress induc exhaust disord multi modal rehabilit mmr programm well health relat qualiti life work abil sick leav level psycholog measur possibl relat | D002055;D011788 | T078;T048 |
36,229,809 | calcan interlock nail treatment calcan fractur multipl center retrospect studi minim invas treatment calcan fractur outcom fewer complic howev technic demand lack reduct tool overcom problem calcan interlock nail system develop make reduct fixat minim invas effect retrospect studi calcan fractur variabl intraop follow evalu outcom patient treat calcan interlock nail system | D002111;D050723;D000072836 | T023;T037 |
36,229,808 | social inequ women expos obstetr gyneco obstetr violenc ecuador cross section studi obstetr gyneco obstetr violenc ov gov concern public health problem particular latin america studi aim determin preval ov gov assess socio geograph distribut ecuador | D014754 | T048 |
36,229,806 | establish evalu modul base immun associ gene signatur predict overal surviv patient colon adenocarcinoma patient colon adenocarcinoma coad exhibit signific heterogen overal surviv current tumor node metastasi stage system insuffici provid precis predict prognosi identif evalu new risk model use big cancer data may provid good way identifi prognosi relat signatur | D000230;D003110 | T191 |
36,229,805 | risk factor prolong preoper wait time intertrochanter fractur patient undergo oper treatment intertrochanter fractur common fractur older adult observ case characterist intertrochanter fractur analyz risk factor prolong preoper wait time base patient data year period investig post admiss treatment intertrochanter fractur | D006620;D014850 | T170;T037 |
36,229,804 | leverag million respons us covid trend impact survey examin vaccin hesit vaccin mask wear januari februari urgenc covid pandem call upon joint effort scientif privat sector work togeth track vaccin accept prevent behavior | D000086382;D014612 | T047;T116;T121;T129;T067 |
36,229,803 | effect salienc reward effort base decis make psychot disord although motiv negat symptom account reduc function qualiti life individu psychot disord under mechan yet fulli understood neuroimag studi suggest impair percept reward cue could result lack incent valu lead decreas goal direct behavior therefor aim studi test effect increas salienc reward cue goal direct behavior | D011618;D012559 | T048 |
36,229,802 | coronari arteri bypass graft patient malign singl institut case seri eight patient surgic strategi among patient malign coronari arteri diseas cad remain controversi studi present experi coronari arteri bypass graft cabg patient malign analyz treatment outcom | D047549;D003324;D009369 | T191;T061;T047 |
36,229,801 | associ metabol healthi obes risk atrial fibril take physic activ consider modif physic activ pa metabol status relat atrial fibril af obes remain unknown aim investig independ joint associ metabol status pa risk af obes popul base data uk biobank studi use cox proport hazard model analys metabol status categor metabol healthi obes mho metabol unhealthi obes muo pa categor four group accord level moder vigor pa mvpa none low medium high total obes particip includ analys mho signific associ reduc af risk compar muo hr ci signific modif pa af risk among individu mho found among muo particip individu medium high pa signific lower af risk compar mvpa hr ci hr ci medium high pa respect sever muo increas modif pa af risk elev accord conclud mho signific associ reduc risk af compar muo obes particip pa could signific modifi relationship metabol status risk af among muo particip particular benefit pa associ reduc af risk muo sever elev | D001281;D024821;D000067329 | T047;T046;T184 |
36,229,800 | rusti pipe syndrom case report review literatur painless bloodi nippl discharg often classifi patholog due associ malign lesion howev also complet harmless condit rusti pipe syndrom rare caus benign self limit bloodi nippl discharg late pregnanc earli lactat given rusti pipe syndrom describ convent textbook thought would appropri bring benign diseas notic reader | D004485;D009558 | T047;T023 |
36,229,799 | new onset relaps liver diseas follow covid vaccin systemat review liver diseas post covid vaccin extrem rare occur grow bodi evid indic portal vein thrombosi autoimmun hepat rais liver enzym liver injuri etc may potenti consequ covid vaccin | D000086382;D000086663;D019693;D017114;D020246 | T047;T046;T200;T067 |
36,229,797 | protect effect l carnitin testosteron synthesi pathway spermatogenesi monosodium glutam induc rat monosodium glutam msg food ingredi increas use commerci msg lead oxid stress consequ suppress steroid hormon product caus defect male reproduct system studi aim evalu effect l carnitin antioxid testicular damag msg induc male rat | D000074385;D012970 | T121;T168;T116 |
36,229,796 | dyadic survey studi partner engag patient receipt guidelin recommend colorect cancer surveil investig whether partner spous intim partner engag colorect cancer crc surveil associ patient receipt surveil | D015179 | T191 |
36,229,795 | cellular messeng involv inhibit arabidopsi primari root growth bacteri quorum sens signal n decanoyl l homoserin lacton n acyl homoserin lacton ahl use quorum sens signal gram negat bacteria also affect plant growth diseas resist n decanoyl l homoserin lacton c hsl ahl shown inhibit primari root growth arabidopsi mechan under effect root architectur unclear investig signal compon involv c hsl mediat inhibit primari root growth arabidopsi interplay use pharmacolog physiolog genet approach | D017360 | T002 |
36,229,794 | clinic analysi women ovarian pregnanc retrospect case control studi address clinic featur potenti risk factor ovarian pregnanc op | D011271;D065172;D011274 | T046 |
36,229,793 | applic machin learn model predict osteoporosi base abdomin comput tomographi imag psoa muscl retrospect studi rapid econom develop world averag life expect increas lead increas preval osteoporosi worldwid howev due complex high cost dual energi x ray absorptiometri dxa examin dxa wide use diagnos osteoporosi addit studi shown psoa index measur third lumbar spine l level close relat bone miner densiti bmd excel predict effect osteoporosi therefor studi develop varieti machin learn ml model base psoa muscl tissu l level unenhanc abdomin comput tomographi ct predict osteoporosi | D010024;D016658 | T047;T023 |
36,229,792 | parent valu prefer underpin treatment decis make poor prognosi childhood cancer scope review parent children diagnos poor prognosi cancer want involv make treatment relat decis child often make repeat decis depend child respons treatment experi decision regret consequ understand parent valu prefer make treatment relat decis may help enhanc discuss healthcar profession identifi addit way provid support parent popul | D003657;D009369 | T191;T041 |
36,229,791 | neck circumfer cut point detect overweight obes among school children northern cyprus neck circumfer one anthropometr paramet wide use practic applic clinic epidemiolog studi children aim determin neck circumfer cut point use detect overweight obes children live northern cyprus | D050177;D063766 | T047;T033 |
36,229,790 | health worker perspect smart triag digit triag platform qualiti improv referr hospit uganda qualit analysi effect triag hospit improv outcom children global help identifi priorit care risk death paper base pediatr triag guidelin develop support frontlin health worker low resourc set guidelin challeng implement smart triag digit triag platform qualiti improv qi aim address challeng smart triag repres major cultur behaviour shift term manag patient health facil low middl incom countri purpos studi understand user perspect usabl feasibl accept smart triag inform ongo futur implement | D058996;D014218 | T061;T057 |
36,229,789 | feasibl accept preliminari effect adapt namast care program deliv caregiv communiti dwell older person moder advanc dementia mix method feasibl studi caregiv consider respons support person advanc stage dementia howev receiv littl educ namast care multisensori program origin design deliv healthcar provid long term care home person advanc dementia program yet adapt evalu use caregiv person moder advanc dementia live home purpos feasibl studi determin feasibl accept preliminari effect adapt namast care program use caregiv communiti dwell older person moder advanc dementia | D017028;D003704 | T098;T097;T099;T048 |
36,229,788 | stabil spatiotempor krige method diseas map applic male oral cancer femal breast cancer taiwan map spacetim diseas rate provid depth understand distribut trend tradit spatiotempor krige method break constraint geopolit boundari time interv still diseas rate dens spars popul area stabil degre result map oversmooth place undersmooth other stabil spatiotempor krige method propos studi overcom problem allow nonconst varianc space time spatiotempor map standard incid ratio oral cancer men taiwan reveal high risk area oral cancer midwestern southeastern region taiwan spread toward center north persist cold spot northern southwestern urban region howev correspond map breast cancer women taiwan reveal high risk area breast cancer concentr dens popul urban region west spatiotempor map facilit understand diseas risk dynam recommend use propos stabil spatiotempor krige method map diseas rate across space time | D001943;D009062 | T191 |
36,229,787 | address racial dispar perinat care african americanblack individu chicago communiti health set qualit studi persist dispar matern infant perinat outcom experienc black birth person compar non hispan white nhw individu us differ outcom aris socioeconom factor individu health behavior also structur racism recent research begin elucid benefit patient navig support underserv minorit individu experi constel barrier equit care qualit research util experi black birth individu expert opinion healthcar provid work serv guid patient navig intervent decreas dispar perinat outcom | D001741;D063505 | T098;T054 |
36,229,786 | diagnost accuraci multiplex respiratori pathogen panel influenza respiratori syncyti virus infect systemat review meta analysi respiratori syncyti virus rsv influenza virus import global caus morbid mortal evalu diagnost accuraci luminex nxtag respiratori pathogen panel rpps index rpps compar detect rsv influenza virus studi compar human clinic respiratori sampl test index least one compar test includ random effect latent class meta analysi perform assess specif sensit index test rsv influenza risk bias assess use quada tool certainti evid use grade ten studi includ rsv predict sensit credibl interv cri specif cri influenza b predict sensit cri cri respect specif cri cri respect evid low certainti although index sensit specif excel compar perform vari research clear patient recruit strategi could ascertain perform across differ populationsprotocol registr prospero crd | D009980;D007251;D018357;D018113 | T047;T005 |
36,229,785 | cultur adapt flowchart obstetr emerg participatori action research studi matern mortal health problem develop countri result sever factor sociodemograph econom inequ difficulti access health servic addit train strategi obstetr emerg target non medic personnel tradit midwiv scarc focus studi develop learn communic bridg manag obstetr emerg polici patient referr biomed health system rural area | D008880;D011225 | T091;T097;T046 |
36,229,784 | histolog molecular respons vigna angulari uromyc vigna infect advanc understand adzuki bean vigna angulari resist infect rust caus fungus uromyc vigna uv comprehens analyz histolog event transcriptom uv infect adzuki bean | D002688;D000070658 | T126;T116;T002 |
36,229,783 | day hospit readmiss mortal surgeri colorect cancer patient hospit readmiss first week follow surgeri common expens associ increas mortal among colorect cancer patient studi design assess day hospit readmiss colorect cancer surgeri evalu risk factor affect hospit readmiss | D015179;D013505 | T191;T061 |
36,229,782 | previous caesarean deliveri presenc caesarean scar defect could affect pregnanc outcom vitro fertil frozen thaw embryo transfer retrospect cohort studi due various iatrogen social factor global caesarean deliveri cd rate risen sharpli past year complic danger women scar uterus experi pregnanc women previous vagin deliveri vd studi investig impact previous caesarean deliveri cd caesarean scar defect csds pregnanc outcom vitro fertil frozen thaw embryo transfer ivf fet | D011256;D047928 | T046;T033 |
36,229,781 | vitaminmineralmicronutri supplement autism spectrum disord research survey vitamin miner supplement wide use children adult diagnos autism spectrum disord asd sever studi report benefit supplement resolv nutrit defici treat various metabol problem improv symptom overal qualiti life | D000067877;D018977 | T123;T048 |
36,229,780 | joint use pool imput genotyp snps despit continu technolog advanc cost larg scale genotyp high number sampl prohibit purpos studi design cost save strategi snp genotyp suggest make use pool group test techniqu drop amount snp array need believ greatest import non model organ limit resourc term cost effici larg scale chip high qualiti refer genom applic wildlif monitor plant anim breed essenc speci agnost propos approach consist group mix individu dna sampl pool test pool bead chip number pool less number individu sampl present statist estim algorithm base pool outcom infer marker wise like genotyp everi sampl pool final input estim genotyp exist imput algorithm compar imput perform pool data beagl algorithm local likelihood awar phase algorithm close model mach implement | D016678;D020641 | T086;T028 |
36,229,779 | psycholog health wellb primari healthcar worker covid pandem malaysia longitudin qualit studi primari healthcar worker phcws frontlin deal viral pandem may experi signific psycholog stress hitherto examin depth aim explor impact covid pandem psycholog health wellb frontlin phcws malaysia | D000086382;D058873 | T047;T067 |
36,229,778 | role microglia blood pressur respiratori respons acut hypox exposur rat microglia modul cardiorespiratori activ chronic hypoxia clarifi whether microglia involv cardiorespiratori respons acut hypoxia investig issu compar cardiorespiratori respons two level acut hypoxia min min conscious unrestrain rat system inject minocyclin mino inhibitor microglia activ mino increas blood pressur lung ventil control normox condit acut hypoxia stimul cardiorespiratori respons mino untreat rat mino fail signific affect magnitud hypoxia induc blood pressur elev contrast mino tend suppress ventilatori respons hypoxia conclud microglia differenti affect cardiorespiratori regul depend level blood oxygen microglia suppress contribut blood pressur regul normoxia help maintain ventilatori augment hypoxia underscor dichotomi central regulatori pathway system | D017628;D008911 | T121;T025;T109;T195 |
36,229,777 | social distanc causal impact spread sar cov us nationwid event studi assess causal impact social distanc spread sar cov us use quasi natur experiment set creat spontan relax social distanc behavior brought protest erupt across nation follow georg floyd tragic death may use differ differ specif balanc sampl cover day event window center onset protest document increas case per day per popul sar cov incid rate protest counti relat propens score match non protest counterpart repres increas incid rate relat week preced protest find treatment effect manifest onset protest placebo test rule possibl find attribut chanc research inform polici maker provid insight regard use social distanc intervent minim spread sar cov | D000086382;D000086402 | T047;T067;T005 |
36,229,776 | clinic prognost analysi children malign rhabdoid tumor kidney year retrospect multi center studi discuss clinic prognost indic pediatr malign rhabdoid tumor kidney mrtk increas understand occurr develop mrtk | D007680;D018335 | T191 |
36,229,775 | screen novel risk factor relat high myopia use machin learn high myopia relat complic becom major caus irrevers vision loss evalu associ potenti factor high myopia provid insight pathophysiolog mechan intervent target myopia progress | D001249;D009216 | T047 |
36,229,774 | efficaci aerob exercis versus strength train treatment migrain systemat review network meta analysi clinic trial multipl clinic trial differ exercis protocol demonstr efficaci manag migrain howev head head comparison efficaci differ exercis intervent | D008881;D055070 | T061;T047 |
36,229,773 | estim effect size hidden causal factor snps continu trait mediat model approach observ studi mendelian random experi use identifi mani causal factor complex trait human given set causal factor import understand extent causal factor explain none genet herit measur singl nucleotid polymorph snps associ trait use mediat model framework snps exposur trait interest outcom known causal factor mediat hypothes unexplain associ snps outcom trait mediat addit unobserv hidden causal factor | D057182;D020641 | T062;T086 |
36,229,772 | comparison safeti immunogen bnt b vaccin chadox vaccin solid organ transplant recipi prospect studi sever acut respiratori syndrom coronavirus sar cov infect result diseas coronavirus diseas covid spread million peopl worldwid preliminari data organ transplant recipi shown reduc seroconvers rate administr differ sar cov vaccin platform howev unknown whether differ vaccin platform provid differ level protect sar cov answer question prospect studi kidney liver transplant recipi kidney n liver n receiv either chadox vaccin n bnt b vaccin n underw assess immunoglobulin mimmunoglobulin g spike antibodi level primari object studi direct compar efficaci two differ vaccin platform solid organ transplant recipi measur immunoglobulin g igg antibodi rbd spike protein anti rbd two week first second dose secondari endpoint solicit specif local system advers event within day receipt dose vaccin differ primari outcom two vaccin platform patient receiv two vaccin dose unrespons main link diabet rate respons first dose among younger older patient signific larger howev second dose differ persist p side effect similar observ pivot trial | D000086382;D000086663;D016377 | T061;T047;T200;T067 |
36,229,771 | aldh knockout protect aortic dissect incid mortal aortic dissect ad increas patholog studi macrophag lymphocyt dendrit cell found tunica media aorta acetaldehyd dehydrogenas aldh gene polymorph associ high incid hypertens asian popul howev clear evid relationship aldh aortic dissect asian aim studi investig incid aortic dissect differ aldh genotyp explor chang vasculatur | D000784;D017545;D001019;D060766 | T047;T046;T167 |
36,229,769 | retin microvasculatur cerebr hemodynam patient intern carotid arteri stenosi investig relationship retin microvasculatur cerebr hemodynam patient intern carotid arteri ica stenosi | D016893 | T047;T020 |
36,229,768 | insight perform phenotyp test versus genotyp test detect carbapenemas produc gram negat bacilli resourc limit set carbapenemas produc gram negat cpgn bacteria impos life threaten infect limit treatment option rigor rapid detect cpgn associ infect usual associ proper treatment better diseas prognosi accord studi aim evalu phenotyp method versus genotyp method use detect pathogen determin sensitivityspecif valu | D000900;D015780 | T121;T109;T195 |
36,229,767 | differenti associ simpl physic perform test global specif cognit function cognit normal mild cognit impair cross section cohort studi asian communiti dwell older adult physic perform declin execut dysfunct predictor dementia howev associ well understood asian older adult without dementia cognit normal cn mild cognit impair mci especi singl studi | D060825;D003704 | T048 |
36,229,752 | folfirinox pharmacodynam interact pancreat cancer cell cultur multi drug combin regim folfirinox standard care chemotherapeut therapi pancreat cancer patient howev systemat evalu potenti pharmacodynam interact among multi drug therapi report previous pharmacodynam interact folfirinox agent fluorouracil fu oxaliplatin oxa sn activ metabolit irinotecan assess across panel primari establish pancreat cancer cell inhibit cell prolifer quantifi drug alon combin obtain quantit drug specif interact paramet assess natur drug interact experiment data analys assum bliss independ interact nonlinear regress model fit conduct sas estim drug interact term psi reveal oxasn combin appear synergist panc ci modest synergist close addit miapaca ci assay tripl combin strong synergist miapaca ci modest synergisticborderlin addit panc ci tripl combin show antagonist interact primari pin panc model quantit pharmacodynam interact describ folfirinox regimen analysi suggest complex interplay among three chemotherapeut agent extens pharmacodynam analysi approach clinicaltransl studi folfirinox combin could reveal addit pharmacodynam interact guid refin regimen achiev optim clinic respons | D000970;D010190 | T121;T109;T191 |
36,229,747 | intracellular extracellular local switch acid lipas enterobact cloaca multi object medium optim aqueous two phase purif activ kinet physiolog impair requir replac therapi continu increas also need improv product acid lipas new microbi sourc enterobact cloaca strain uccm produc novel acid lipas kernel oil process wast basal broth extracellular intracellular local ratio research direct enzym local extracellular milieu reduc recoveri cost use multi object respons surfac optim medium paramet result reveal extracellular intracellular lipas ratio product format kinet model luedek piret function show signific switch complet growth associ intracellular product predomin non growth associ extracellular local medium optim aqueous two phase system purif condit extract lipas puriti v max molmin k mmol enzym activ enhanc k ca ion stabl mani organ solvent except aceton ph temperatur optima c respect | D016972;D008049 | T007;T126;T116;T121 |
36,229,746 | deriv wetland cover type wcts integr multispectr indic base earth observ data wetland cover defin spatial homogen region wetland attribut under biophys condit veget turbid hydric soil amount water present novel method deriv wetland cover type wcts combin three common use multispectr indic ndvi mndwi ndti three larg ramsar wetland locat differ geomorph climat set across india wetland includ kaabar tal floodplain wetland east ganga plain chilika lagoon coastal wetland eastern india nal sarovar semi arid western india novelti approach deriv wcts stabl space time therefor given wct across differ wetland within differ zone larg wetland impli similar under biophys attribut wcts therefor provid novel tool monitor chang detect wetland cover type autom propos wct algorithm use googl earth engin gee environ develop arcgi tool method implement wetland use multispectr imageri dataset visibl nir band propos methodolog simpl yet robust easi implement therefor hold signific import wetland monitor manag | D004784;D053833 | T057;T083;T070 |
36,229,744 | make anoth life possibl bacteria global regul architect bacteri biofilm biofilm structur main mode evolutionari reproduct adapt bacteria even featur alon suffici make focus genet physiolog studi life form multicellular like life form coordin genet physiolog program quit differ plankton form bacteri biofilm often compos one speci natur clear divis labor nutrient channel languag signal establish cell form biofilm hand biofilm especi form pathogen caus import industri clinic problem due high resist environment stress condit obtain new data molecular basi bacteri evolut understand intra inter speci ecosystem relat context well find perman solut serious problem creat direct relat detail understand genet regul bacteri biofilm structur today becom increas certain environment signal effect transit plankton form biofilm form receptorrespons molecul general manag similar system global regul molecul bacteria sens besid quorum sens qs system cyclic adenosin monophosph catabolit suppressor protein camp crp bis cyclic dimer guanosin monophosph c di gmp signal molecul critic import review articl current inform bacteri biofilm summar interpret base framework | D017753;D015964 | T082;T045;T070 |
36,229,735 | role effect base method address water qualiti monitor south africa develop countri struggl water import resourc worldwid struggl provid water good qualiti whole popul despit good govern law guidelin set place help protect water resourc ensur good qualiti various consum water qualiti south africa worsen due lack manag deterior infrastructur becom progress wors due corrupt insuffici fund ever increas number toxic well identif emerg chemic concern also challeng south africa face chemic analysi determin total biolog effect mixtur chemic compound shortcom address ad effect base method ebm water qualiti monitor programm paper current status water qualiti monitor south africa discuss well capac countri add ebm water qualiti monitor programm protect improv human anim life creat biorendercom | D060753;D003906 | T080;T033 |
36,229,730 | altern approach combin lockdown open fight covid pandem covid pandem enter third year omicron variant becom domin propos altern strategi deal covid call hybrid lockdown combin lockdown central organ lockdown high risk popul free mobil normal mobil low risk popul approach enabl countri region especi high popul densiti achiev signific prevent control effect covid pandem least cost | D000086382 | T047;T067 |
36,229,720 | analysi eutroph wetland use data driven model eutroph major problem intern anzali wetland northern iran present research initi aim determin trophic state index tsi ten sampl site main part anzali wetland western eastern central siahkeshim part determin tsi wetland data driven method classif tree model j algorithm implement predict trophic condit wetland base set water qualiti physic structur variabl one hundr twenti sampl relat chlorophyl model output environment variabl model input measur month year studi period base tsi calcul western siahkeshim eastern central part wetland classifi eutroph super eutroph hyper eutroph hyper eutroph respect environment variabl introduc model five time random effort prune confid factor seven fold cross valid eight variabl bicarbon ph water temperatur electr conduct dissolv oxygen total phosphorus water depth water turbid predict model model predict increas total phosphat water turbid electr conduct concentr may contribut hyper eutroph state wetland contrast hyper eutroph wetland associ decreas water depth dissolv oxygen ph concentr accord anova test trophic condit wetland affect spatial tempor pattern anthropogen pressur influx chemic particular nutrient phosphorus nitrogen main caus water enrich eutroph problem main part anzali wetland ecosystem | D017753;D053833 | T082;T083;T070 |
36,229,717 | local thermal effect power set monopolar coagul three dimension electrotherm coupl finit element studi three dimension electrotherm coupl finit element fe model use simul analyz effect electrosurg power set temperatur distribut thermal damag biolog tissu coagul discuss paramet includ power durat contact distanc electrosurg blade tissu surfac inclin angl blade cut result indic condit constant input electr energi maxim temperatur decreas power time shorten power paus durat increas two contact distanc blade tissu mm show signific temperatur differ howev tissu temperatur increas increas blade inclin angl conclud use normal cut angl set multipl shorter time power intermitt power oper procedur reduc risk thermal damag monopolar electrosurgeri | D004598;D013525 | T061;T074 |
36,229,713 | sea lamprey alarm cue compris water chloroform solubl compon divers aquat organ manag predat risk avoid water activ conspecif alarm cue chemic mixtur releas injuri sea lamprey petromyzon marinus nocturn migratori speci reli alarm cue navig around area predat risk move river channel identif cue chemistri would allow manag har innat behavior respons guid migrat sea lamprey trap invas popul laurentian great lake fish passag devic dam block migrat nativ rang pursu isol sea lamprey alarm cue behavior guid fraction fraction alarm cue water solubl chloroform solubl fraction elicit substanti avoid respons recombin two fraction restor full reactiv suggest alarm cue mixtur contain compon exhibit high solubl water eg nitrogen compound chloroform eg lipid perhap materi dissolv readili either solvent screen individu compound pure isol sub fraction water solubl fraction found one pure isol isoleucin evok avoid respons consist found mixtur third experi observ behavior respons recombin compound isol identifi water solubl fraction result confirm suggest process elucid alarm cue constitu challeng howev suggest pursuit worthwhil given strong evid util alarm cue use conserv manag fish aquat organ | D048428 | T013 |
36,229,706 | stage structur continu discret time popul model persist spatial spread popul persist spatial propag depend demographi dispers great import spatial ecolog mani speci high structur life cycl invad new habitat dispers organ earli life stage eg seed larva etc develop stage structur continuousdiscret time hybrid model describ spatiotempor dynam speci reaction diffus equat describ random movement dispers individu two differ equat describ demographi sedentari individu obtain formula spread speed popul term model paramet show spread speed character slowest wave speed class travel wave solut provid explicit formula critic domain size separ popul persist extinct compar stage structur model physic unstructur model find structur model reduc unstructur one special case accord result spread speed critic domain size unstructur model repres special case structur one highlight signific includ stage structur studi spatial dynam speci complex life cycl | D055641;D008954 | T075;T081 |
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