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https://en.wikipedia.org/wiki/Sirna
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Sirna may refer to:
Sírna, legendary High King of Ireland
Șirna, a commune in Prahova County, Romania
Sirna, Iran, a village in Markazi Province, Iran
Small interfering RNA (siRNA)
Syrna, also spelled Sirna, Greek village
Syrna (island), also spelled Sirna, Greek island
Sirna Therapeutics
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https://en.wikipedia.org/wiki/BasicX
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BasicX is a free programming language designed specifically for NetMedia's BX-24 microcontroller and based on the BASIC programming language. It is used in the design of robotics projects such as the Robodyssey Systems Mouse robot.
Further reading
Odom, Chris D. BasicX and Robotics. Robodyssey Systems LLC,
External links
NetMedia Home Page
BasicX Free Downloads
Sample Code
, programmed in BasicX
Videos, Sample Code, and Tutorials from the author of BasicX and Robotics
BASIC compilers
Embedded systems
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https://en.wikipedia.org/wiki/Division%20No.%205%2C%20Saskatchewan
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Division No. 5 is one of eighteen census divisions in the province of Saskatchewan, Canada, as defined by Statistics Canada. It is located in the east-southeastern part of the province, bordering Manitoba. The most populous community in this division is Melville.
Demographics
In the 2021 Census of Population conducted by Statistics Canada, Division No. 5 had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
Census subdivisions
The following census subdivisions (municipalities or municipal equivalents) are located within Saskatchewan's Division No. 5.
Cities
Melville
Towns
Bredenbury
Broadview
Churchbridge
Esterhazy
Fleming
Grenfell
Kipling
Langenburg
Lemberg
Moosomin
Rocanville
Saltcoats
Wapella
Whitewood
Wolseley
Villages
Atwater
Bangor
Dubuc
Duff
Fenwood
Gerald
Glenavon
Goodeve
Grayson
Killaly
MacNutt
Neudorf
Spy Hill
Stockholm
Tantallon
Waldron
Welwyn
Windthorst
Yarbo
Resort villages
Bird's Point
Melville Beach
West End
Rural municipalities
RM No. 121 Moosomin
RM No. 122 Martin
RM No. 123 Silverwood
RM No. 124 Kingsley
RM No. 125 Chester
RM No. 151 Rocanville
RM No. 152 Spy Hill
RM No. 153 Willowdale
RM No. 154 Elcapo
RM No. 155 Wolseley
RM No. 181 Langenburg
RM No. 183 Fertile Belt
RM No. 184 Grayson
RM No. 185 McLeod
RM No. 211 Churchbridge
RM No. 213 Saltcoats
RM No. 214 Cana
RM No. 215 Stanley
Indian reserves
Cowessess Fir
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https://en.wikipedia.org/wiki/Division%20No.%206%2C%20Saskatchewan
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Division No. 6 is one of eighteen census divisions in the province of Saskatchewan, Canada, as defined by Statistics Canada. It is located in the south-central part of the province. The most populous community in this division is Regina, the provincial capital.
Demographics
In the 2021 Census of Population conducted by Statistics Canada, Division No. 6 had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
Census subdivisions
The following census subdivisions (municipalities or municipal equivalents) are located within Saskatchewan's Division No. 6.
Cities
Regina
Towns
Balcarres
Balgonie
Cupar
Fort Qu'Appelle
Francis
Grand Coulee
Indian Head
Lumsden
Pilot Butte
Qu'Appelle
Regina Beach
Rouleau
Sintaluta
Southey
Strasbourg
White City
Villages
Abernethy
Belle Plaine
Bethune
Briercrest
Buena Vista
Bulyea
Chamberlain
Craven
Dilke
Disley
Drinkwater
Dysart
Earl Grey
Edenwold
Findlater
Holdfast
Kendal
Lebret
Lipton
Markinch
McLean
Montmartre
Odessa
Pense
Sedley
Silton
Vibank
Wilcox
Resort villages
Alice Beach
B-Say-Tah
Fort San
Glen Harbour
Grandview Beach
Island View
Kannata Valley
Katepwa
Lumsden Beach
North Grove
Pelican Pointe
Saskatchewan Beach
Sunset Cove
Wee Too Beach
Rural municipalities
RM No. 126 Montmartre
RM No. 127 Francis
RM No. 128 Lajord
RM No. 129 Bratt's Lake
RM No. 130 Redburn
RM No. 156 Indian Head
RM No. 157 South Qu'Appelle
RM N
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https://en.wikipedia.org/wiki/Division%20No.%207%2C%20Saskatchewan
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Division No. 7 is one of eighteen census divisions in the province of Saskatchewan, Canada, as defined by Statistics Canada. It is located in the south-central part of the province. The most populous community in this division is Moose Jaw.
Demographics
In the 2021 Census of Population conducted by Statistics Canada, Division No. 7 had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
Census subdivisions
The following census subdivisions (municipalities or municipal equivalents) are located within Saskatchewan's Division No. 7.
Cities
Moose Jaw
Towns
Central Butte
Craik
Herbert
Morse
Villages
Aylesbury
Beechy
Brownlee
Caronport
Chaplin
Coderre
Ernfold
Eyebrow
Hodgeville
Keeler
Lucky Lake
Marquis
Mortlach
Riverhurst
Rush Lake
Shamrock
Tugaske
Tuxford
Waldeck
Resort villages
Beaver Flat
Coteau Beach
Mistusinne
South Lake
Sun Valley
Rural municipalities
RM No. 131 Baildon
RM No. 132 Hillsborough
RM No. 133 Rodgers
RM No. 134 Shamrock
RM No. 135 Lawtonia
RM No. 136 Coulee
RM No. 161 Moose Jaw
RM No. 162 Caron
RM No. 163 Wheatlands
RM No. 164 Chaplin
RM No. 165 Morse
RM No. 166 Excelsior
RM No. 191 Marquis
RM No. 193 Eyebrow
RM No. 194 Enfield
RM No. 222 Craik
RM No. 223 Huron
RM No. 224 Maple Bush
RM No. 225 Canaan
RM No. 226 Victory
RM No. 255 Coteau
RM No. 256 King George
Other communities
Hamlets
Bateman
Birsay
Bushell Park
Car
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https://en.wikipedia.org/wiki/Division%20No.%208%2C%20Saskatchewan
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Division No. 8 is one of eighteen census divisions in the province of Saskatchewan, Canada, as defined by Statistics Canada. It is located in the west-southwestern part of the province, bordering Alberta. The most populous community in this division is Swift Current.
Demographics
In the 2021 Census of Population conducted by Statistics Canada, Division No. 8 had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
Census subdivisions
The following census subdivisions (municipalities or municipal equivalents) are located within Saskatchewan's Division No. 8.
Cities
Swift Current
Towns
Burstall
Cabri
Eatonia
Elrose
Eston
Gull Lake
Kyle
Leader
Villages
Abbey
Fox Valley
Golden Prairie
Hazlet
Lancer
Mendham
Pennant
Prelate
Richmound
Sceptre
Shackleton
Stewart Valley
Success
Tompkins
Webb
Rural municipalities
RM No. 137 Swift Current
RM No. 138 Webb
RM No. 139 Gull Lake
RM No. 141 Big Stick
RM No. 142 Enterprise
RM No. 167 Saskatchewan Landing
RM No. 168 Riverside
RM No. 169 Pittville
RM No. 171 Fox Valley
RM No. 228 Lacadena
RM No. 229 Miry Creek
RM No. 230 Clinworth
RM No. 231 Happyland
RM No. 232 Deer Forks
RM No. 257 Monet
RM No. 259 Snipe Lake
RM No. 260 Newcombe
RM No. 261 Chesterfield
Indian reserves
Carry the Kettle Nakoda Nation
Carry the Kettle 76-33
Carry the Kettle 76-37
Carry the Kettle 76-38
Unincorporated communities
Ham
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https://en.wikipedia.org/wiki/Division%20No.%209%2C%20Saskatchewan
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Division No. 9, Canada, is one of the eighteen census divisions within the province of Saskatchewan, as defined by Statistics Canada. It is located in the eastern part of the province, bordering Manitoba. The most populous community in this division is Yorkton.
Demographics
In the 2021 Census of Population conducted by Statistics Canada, Division No. 9 had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
Census subdivisions
The following census subdivisions (municipalities or municipal equivalents) are located within Saskatchewan's Division No. 9.
Cities
Yorkton
Towns
Canora
Kamsack
Norquay
Preeceville
Springside
Sturgis
Villages
Arran
Buchanan
Calder
Ebenezer
Endeavour
Hyas
Invermay
Lintlaw
Pelly
Rama
Rhein
Sheho
Stenen
Theodore
Togo
Rural municipalities
RM No. 241 Calder
RM No. 243 Wallace
RM No. 244 Orkney
RM No. 245 Garry
RM No. 271 Cote
RM No. 273 Sliding Hills
RM No. 274 Good Lake
RM No. 275 Insinger
RM No. 301 St. Philips
RM No. 303 Keys
RM No. 304 Buchanan
RM No. 305 Invermay
RM No. 331 Livingston
RM No. 333 Clayton
RM No. 334 Preeceville
RM No. 335 Hazel Dell
Indian reserves
Cote First Nation
Cote 64
Keeseekoose First Nation
Keeseekoose 66
Keeseekoose 66A
Keeseekoose 66-CA-04
Keeseekoose 66-CA-05
Keeseekoose 66-CA-06
Keeseekoose 66-KE-04
Keeseekoose 66-KE-05
The Key First Nation
The Key 65
See also
List of cens
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https://en.wikipedia.org/wiki/Division%20No.%2010%2C%20Saskatchewan
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Division No. 10 is one of eighteen census divisions in the province of Saskatchewan, Canada, as defined by Statistics Canada. It is located in the east-central part of the province. The most populous community in this division is Wynyard.
Demographics
In the 2021 Census of Population conducted by Statistics Canada, Division No. 10 had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
Census subdivisions
The following census subdivisions (municipalities or municipal equivalents) are located within Saskatchewan's Division No. 10.
Cities
none
Towns
Foam Lake
Ituna
Leroy
Raymore
Wadena
Watson
Wynyard
Villages
Elfros
Hubbard
Jansen
Kelliher
Leross
Lestock
Margo
Punnichy
Quill Lake
Quinton
Semans
Resort villages
Chorney Beach
Leslie Beach
Rural municipalities
RM No. 246 Ituna Bon Accord
RM No. 247 Kellross
RM No. 248 Touchwood
RM No. 276 Foam Lake
RM No. 277 Emerald
RM No. 279 Mount Hope
RM No. 307 Elfros
RM No. 308 Big Quill
RM No. 309 Prairie Rose
RM No. 336 Sasman
RM No. 337 Lakeview
RM No. 338 Lakeside
RM No. 339 Leroy
Source: Statistics Canada 2002 2001 Community Profiles
Indian reserves
Beardy's and Okemasis 96 and 97A
Day Star 87
Fishing Lake 89
Fishing Lake 89A
Gordon 86
Muskowekwan 85
Muskowekwan 85-1
Muskowekwan 85-10
Muskowekwan 85-12
Muskowekwan 85-15
Muskowekwan 85-17
Muskowekwan 85-22
Muskowekwan 85-23
Muskowekwan
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https://en.wikipedia.org/wiki/Division%20No.%2011%2C%20Saskatchewan
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Division No. 11 is one of eighteen census divisions in the province of Saskatchewan, Canada, as defined by Statistics Canada. It is located in the central part of the province and includes the largest city in the province, Saskatoon.
Demographics
In the 2021 Census of Population conducted by Statistics Canada, Division No. 11 had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
Census subdivisions
The following census subdivisions (municipalities or municipal equivalents) are located within Saskatchewan's Division No. 11.
Cities
Martensville
Saskatoon
Warman
Towns
Allan
Colonsay
Dalmeny
Davidson
Dundurn
Govan
Hanley
Imperial
Langham
Lanigan
Nokomis
Osler
Outlook
Watrous
Villages
Bladworth
Bradwell
Broderick
Clavet
Drake
Duval
Elbow
Glenside
Kenaston
Liberty
Loreburn
Hawarden
Meacham
Plunkett
Simpson
Strongfield
Viscount
Young
Zelma
Resort villages
Etters Beach
Manitou Beach
Shields
Thode
Rural municipalities
RM No. 250 Last Mountain Valley
RM No. 251 Big Arm
RM No. 252 Arm River
RM No. 253 Willner
RM No. 254 Loreburn
RM No. 280 Wreford
RM No. 281 Wood Creek
RM No. 282 McCraney
RM No. 283 Rosedale
RM No. 284 Rudy
RM No. 310 Usborne
RM No. 312 Morris
RM No. 313 Lost River
RM No. 314 Dundurn
RM No. 340 Wolverine
RM No. 341 Viscount
RM No. 342 Colonsay
RM No. 343 Blucher
RM No. 344 Corman Park
Indian reserves
Whitecap
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https://en.wikipedia.org/wiki/Division%20No.%2012%2C%20Saskatchewan
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Division No. 12 is one of the eighteen census divisions in the province of Saskatchewan, Canada, as defined by Statistics Canada. It is located in the west-central part of the province. The most populous community in this division is Battleford.
Demographics
In the 2021 Canadian census conducted by Statistics Canada, Division No. 12 had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
Census subdivisions
The following census subdivisions (municipalities or municipal equivalents) are located within Saskatchewan's Division No. 12.
Cities
none
Towns
Battleford
Biggar
Delisle
Rosetown
Zealandia
Villages
Asquith
Conquest
Dinsmore
Harris
Kinley
Macrorie
Milden
Perdue
Tessier
Vanscoy
Wiseton
Rural municipalities
RM No. 285 Fertile Valley
RM No. 286 Milden
RM No. 287 St. Andrews
RM No. 288 Pleasant Valley
RM No. 315 Montrose
RM No. 316 Harris
RM No. 317 Marriott
RM No. 318 Mountain View
RM No. 345 Vanscoy
RM No. 346 Perdue
RM No. 347 Biggar
RM No. 376 Eagle Creek
RM No. 377 Glenside
RM No. 378 Rosemount
RM No. 408 Prairie
RM No. 438 Battle River
Indian reserves
Grizzly Bear's Head 110 and Lean Man 111
Mosquito 109
Red Pheasant 108
Sweet Grass 113
Sweet Grass 113-M16
See also
List of census divisions of Saskatchewan
List of communities in Saskatchewan
Notes
References
Division No. 12, Saskatchewan Statistics Canada
12
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https://en.wikipedia.org/wiki/Division%20No.%2013%2C%20Saskatchewan
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Division No. 13 is one of eighteen census divisions in the province of Saskatchewan, Canada, as defined by Statistics Canada. It is located in the western part of the province, bordering Alberta. The most populous community in this division is Kindersley.
Demographics
In the 2021 Census of Population conducted by Statistics Canada, Division No. 13 had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
Census subdivisions
The following census subdivisions (municipalities or municipal equivalents) are located within Saskatchewan's Division No. 13.
Cities
none
Towns
Cut Knife
Kerrobert
Kindersley
Luseland
Macklin
Scott
Unity
Wilkie
Villages
Brock
Coleville
Denzil
Dodsland
Flaxcombe
Landis
Major
Marengo
Marsden
Neilburg
Netherhill
Plenty
Ruthilda
Senlac
Smiley
Tramping Lake
Rural municipalities
RM No. 290 Kindersley
RM No. 292 Milton
RM No. 319 Winslow
RM No. 320 Oakdale
RM No. 321 Prairiedale
RM No. 322 Antelope Park
RM No. 349 Grandview
RM No. 350 Mariposa
RM No. 351 Progress
RM No. 352 Heart's Hill
RM No. 379 Reford
RM No. 380 Tramping Lake
RM No. 381 Grass Lake
RM No. 382 Eye Hill
RM No. 409 Buffalo
RM No. 410 Round Valley
RM No. 411 Senlac
RM No. 439 Cut Knife
RM No. 440 Hillsdale
RM No. 442 Manitou Lake
Indian reserves
Indian Reserve - Little Pine 116
Indian Reserve - Poundmaker 114
See also
List of census divisions of Saskat
|
https://en.wikipedia.org/wiki/Division%20No.%2014%2C%20Saskatchewan
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Division No. 14 is one of eighteen census divisions in the province of Saskatchewan, Canada, as defined by Statistics Canada. It is located on the northern portion of Southeast Saskatchewan, bordering Manitoba. The most populous community in this division is the city of Melfort. Other important communities are the towns of Nipawin and Tisdale.
Demographics
In the 2021 Census of Population conducted by Statistics Canada, Division No. 14 had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
Census subdivisions
The following census subdivisions (municipalities or municipal equivalents) are located within Saskatchewan's Division No. 14.
Cities
Melfort
Towns
Arborfield
Carrot River
Choiceland
Hudson Bay
Kelvington
Naicam
Nipawin
Porcupine Plain
Rose Valley
Star City
Tisdale
Villages
Archerwill
Aylsham
Bjorkdale
Codette
Fosston
Love
Mistatim
Pleasantdale
Ridgedale
Smeaton
Spalding
Valparaiso
Weekes
White Fox
Zenon Park
Resort villages
Tobin Lake
Rural municipalities
RM No. 366 Kelvington
RM No. 367 Ponass Lake
RM No. 368 Spalding
RM No. 394 Hudson Bay
RM No. 395 Porcupine
RM No. 397 Barrier Valley
RM No. 398 Pleasantdale
RM No. 426 Bjorkdale
RM No. 427 Tisdale
RM No. 428 Star City
RM No. 456 Arborfield
RM No. 457 Connaught
RM No. 458 Willow Creek
RM No. 486 Moose Range
RM No. 487 Nipawin
RM No. 488 Torch River
Indian reserves
Carrot River
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https://en.wikipedia.org/wiki/Division%20No.%2015%2C%20Saskatchewan
|
Division No. 15 is one of eighteen census divisions in the province of Saskatchewan, Canada, as defined by Statistics Canada. It is located in the north-central part of the province. The most populous community in this division is Prince Albert.
Demographics
In the 2021 Census of Population conducted by Statistics Canada, Division No. 15 had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
Census subdivisions
The following census subdivisions (municipalities or municipal equivalents) are located within Saskatchewan's Division No. 15.
Cities
Humboldt
Prince Albert
Melfort
Towns
Aberdeen
Birch Hills
Bruno
Cudworth
Duck Lake
Hague
Kinistino
Rosthern
St. Brieux
Vonda
Wakaw
Waldheim
Villages
Albertville
Alvena
Annaheim
Beatty
Christopher Lake
Englefeld
Hepburn
Laird
Lake Lenore
Meath Park
Middle Lake
Muenster
Paddockwood
Pilger
Prud'Homme
St. Benedict
St. Gregor
St. Louis
Weirdale
Weldon
Resort villages
Candle Lake
Wakaw Lake
Rural municipalities
RM No. 369 St. Peter
RM No. 370 Humboldt
RM No. 371 Bayne
RM No. 372 Grant
RM No. 373 Aberdeen
RM No. 399 Lake Lenore
RM No. 400 Three Lakes
RM No. 401 Hoodoo
RM No. 402 Fish Creek
RM No. 403 Rosthern
RM No. 404 Laird
RM No. 429 Flett's Springs
RM No. 430 Invergordon
RM No. 431 St. Louis
RM No. 459 Kinistino
RM No. 460 Birch Hills
RM No. 461 Prince Albert
RM No. 463 Duck Lake
RM No. 490 Garden
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https://en.wikipedia.org/wiki/Division%20No.%2016%2C%20Saskatchewan
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Division No. 16 is one of eighteen census divisions in the province of Saskatchewan, Canada, as defined by Statistics Canada. It is located in the north-central part of the province. The most populous community in this division is North Battleford.
Demographics
In the 2021 Census of Population conducted by Statistics Canada, Division No. 16 had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
Census subdivisions
The following census subdivisions (municipalities or municipal equivalents) are located within Saskatchewan's Division No. 16.
Cities
North Battleford
Towns
Big River
Blaine Lake
Hafford
Radisson
Shellbrook
Spiritwood
Villages
Borden
Canwood
Debden
Denholm
Krydor
Leask
Leoville
Marcelin
Maymont
Medstead
Parkside
Richard
Ruddell
Shell Lake
Speers
Resort villages
Big Shell
Echo Bay
Pebble Baye
Rural municipalities
RM No. 405 Great Bend
RM No. 406 Mayfield
RM No. 434 Blaine Lake
RM No. 435 Redberry
RM No. 436 Douglas
RM No. 437 North Battleford
RM No. 464 Leask
RM No. 466 Meeting Lake
RM No. 467 Round Hill
RM No. 493 Shellbrook
RM No. 494 Canwood
RM No. 496 Spiritwood
RM No. 497 Medstead
RM No. 555 Big River
Crown colonies
North Battleford Crown Colony
Unorganized areas
Prince Albert National Park
Indian reserves
Indian Reserve --Ahtahkakoop 104
Indian Reserve --Big River 118
Indian Reserve --Chitek Lake 191
Indian Reser
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https://en.wikipedia.org/wiki/Division%20No.%2017%2C%20Saskatchewan
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Division No. 17 is one of eighteen census divisions in the province of Saskatchewan, Canada, as defined by Statistics Canada. It is located in the west-northwest part of the province, bordering Alberta. The most populous community in this division is the interprovincial city of Lloydminster. Another important population centre is the town of Meadow Lake.
Demographics
In the 2021 Census of Population conducted by Statistics Canada, Division No. 17 had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
Census subdivisions
The following census subdivisions (municipalities or municipal equivalents) are located within Saskatchewan's Division No. 17.
Cities
Lloydminster
Meadow Lake
Towns
Lashburn
Maidstone
Marshall
St. Walburg
Turtleford
Villages
Dorintosh
Edam
Glaslyn
Goodsoil
Loon Lake
Makwa
Meota
Mervin
Paradise Hill
Paynton
Pierceland
Waseca
Resort villages
Aquadeo
Cochin
Greig Lake
Kivimaa-Moonlight Bay
Metinota
Rural municipalities
RM No. 468 Meota
RM No. 469 Turtle River
RM No. 470 Paynton
RM No. 471 Eldon
RM No. 472 Wilton
RM No. 498 Parkdale
RM No. 499 Mervin
RM No. 501 Frenchman Butte
RM No. 502 Brittania
RM No. 561 Loon Lake
RM No. 588 Meadow Lake
RM No. 622 Beaver River
Indian reserves
Big Island Lake Cree Nation
Eagles Lake 165C
Flying Dust First Nation 105
Makaoo 120
Makwa Lake 129
Makwa Lake 129A
Makwa Lake 129B
Makwa L
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https://en.wikipedia.org/wiki/Division%20No.%2018%2C%20Saskatchewan
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Division No. 18, Saskatchewan, Canada, is one of the eighteen Statistics Canada census divisions within the province, occupying the northern half of the province. The census division is coextensive with the Northern Saskatchewan Administration District (NSAD).
The census division is the largest in the province terms of area at , representing 46 per cent of the province's entire area of .
The most populous communities in the census division are La Ronge and La Loche with populations of 2,743 and 2,611 respectively.
Demographics
In the 2021 Census of Population conducted by Statistics Canada, Division No. 18 had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
Census subdivisions
Division No. 18 has 58 census subdivisions, of which 24 are municipalities (including a portion of the City of Flin Flon, a city bisected by the Saskatchewan-Manitoba border, 2 northern towns, 11 northern villages and 10 northern hamlets), 32 are First Nations communities (31 Indian reserves and an Indian settlement), an unincorporated northern settlement and the unorganized balance of Division No. 18. All municipalities within the census division, except for the Northern Hamlet of Black Point, are recognized as census subdivisions.
Cities
Northern towns
Northern villages
Northern hamlets
Indian settlements
Indian reserves
Unincorporated communities
A northern settlement i
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https://en.wikipedia.org/wiki/Ren%C3%A9%20Gateaux
|
René Eugène Gateaux (; 5 May 1889 – 3 October 1914) was a French mathematician. He is principally known for the Gateaux derivative, used in the calculus of variations and in the theory of optimal control. He died in combat during World War I. Paul Lévy produced a posthumous edition of his works, extending them considerably, in his Leçons d'analyse fonctionnelle of 1922.
Life
Early years
Gateaux was born on at Vitry-le-François, Marne, 222 years after another mathematician, Abraham de Moivre, was born there (de Moivre, being of Huguenot ancestry, fled to London after the Edict of Fontainebleau of 1685). His father had a small saddlery and upholstery business, and his mother was a seamstress. He was schooled at Reims, and in 1907 entered the École normale supérieure (ENS) on the rue d'Ulm. He was well regarded as one of the most promising mathematicians among his peers. During his time at ENS, Gateaux converted to Roman Catholicism.
Schoolteacher
In 1910, he sat the mathematics examination (being placed 11th of 16 in his year, a somewhat unimpressive result perhaps due to his being so young, according to the ENS's deputy head Émile Borel). He became a teacher at the lycée in Bar-le-Duc, Meuse in 1912, having completed his two years' military service (the first as a private soldier, and the second as a sub-lieutenant, as was required by a 1905 law concerning the service of students from some Grandes Écoles).
At the same time as he took the post at Bar-le-Duc, he started
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https://en.wikipedia.org/wiki/Motorola%20V120c
|
The Motorola V120c is a CDMA cell phone sold in 2002 by Motorola. It was mainly used with Verizon and Alltel networks, and included a number of simple features. It had an extendable antenna.
The model existed in black and in silver, but there were other plastic covers from third party manufacturers.
It was very similar to the Motorola v60, but it had only one screen and it was a candybar format phone instead of a clamshell.
A big criticism was the unreliable software that the phone had, with several bugs.
There also exists a TDMA version, called v120t. It had a fixed antenna.
It was rated number three on the list of the ten highest radiation-emitting cell phones.
V120c
Mobile phones introduced in 2002
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https://en.wikipedia.org/wiki/Lake%20Quannapowitt
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Lake Quannapowitt is a lake in Wakefield, Massachusetts. It is one of the two large lakes in Wakefield, the other being the man-made Crystal Lake. The lake is named for Quonopohit, the Naumkeag Native American man who signed a deed to the town that would become Wakefield in 1686. Given its easily accessible location off Route 128 in Middlesex County, Lake Quannapowitt is a popular setting for walkers, joggers, bikers, and in-line skaters. It is the site of many organized races from 5Ks to ultramarathons. Since 1992, Friends of Lake Quannapowitt (FOLQ) has operated as an organization working to fulfill its goal of promoting public awareness and providing long-term protection and enhancement of Lake Quannapowitt and its environs. Large amounts of tar were found in the lake some years ago, a by-product of gas manufacturing from coal. The lake is emptied by the Saugus River.
Lake Quannapowitt (KWAN-ah-POW-it / KWAN-ə-POW-it), which was originally known as Reading Pond, has numerous nicknames today. Some area natives refer to the lake as "Lake Quannapolluted", due to their view of the state of health of the lake, but the Massachusetts Department of Environmental Protection handled only one isolated open case of contamination from the electric company that was remediated in 2008. The two former beaches remain closed to swimming, due to arsenic, which was introduced into the lake in the early 1960s to handle aquatic weeds.
The town common of Wakefield abuts the southeastern shore
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https://en.wikipedia.org/wiki/Reniform
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Reniform is an adjective meaning "kidney-shaped". It may refer to:
Reniform habit, a type of crystal shape
Reniform leaf, a plant leaf shape
Reniform seed, a plant seed shape
Reniform stigma, a spot on the wings of certain moths
See also
Runiform (disambiguation)
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https://en.wikipedia.org/wiki/SBB-CFF-FFS%20RBDe%20560
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The RBDe 560 (in the old naming style, the RBDe 4/4) and its derivatives provide motive power for S-Bahn, suburban, and regional traffic on the Swiss Federal Railways (SBB) network. The derivative versions belong to the SBB as well as various private railroads. The locomotive and its matching Bt model Steuerwagen (translation: control car/cab car/driving trailer) form compositions generally known as the Neuer Pendelzug (New Push-pull Train), which is the source of the acronym NPZ. An NPZ trainset usually includes one or more intermediate cars.
General information
In 1984 four pre-series sets (each consisting of a motor car and a driving trailer) were delivered. Ordered in 1981, they originally bore the RBDe 4/4 designation and road numbers 2100-2103. All four trainsets (RBDe 560 + Bt) were delivered in different color schemes, one of which was the livery used for the main series (blue over white sides, yellow doors, and red faces). The striking contrast to the green color scheme of previous SBB passenger stock led to the name Kolibri (Hummingbird), which is, however, rarely used. Nearly all the RBDe 560 sets have been named after smaller municipalities along the lines served by these trainset received the appropriate coat of arms.
A full order for 80 trainsets followed. A few years later an additional order for a further 42 trainsets was placed. 6 trainsets were ordered by private railroads (Südostbahn (SOB), PBr, MThB, Montafonerbahn, etc.), resulting in a total productio
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https://en.wikipedia.org/wiki/Haplogroup%20E%20%28mtDNA%29
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In human mitochondrial genetics, haplogroup E is a human mitochondrial DNA (mtDNA) haplogroup typical for the Malay Archipelago. It is a subgroup of haplogroup M9.
Origin
Two contrasting proposals have been made for the location and time of the origin of Haplogroup E.
One view is that the clade was formed over 30,000 years ago, around the time of the Last Glacial Maximum, on the northeast coast of Sundaland (near modern Borneo).
In this model, the haplogroup was dispersed by rising sea levels during the Late Glacial period.
In 2014, the mitochondrial DNA of an 8,000-year-old skeleton found on Liang Island, one of the Matsu Islands off the southeast China coast, was found to belong to Haplogroup E, with two of the four mutations characteristic of the E1 subgroup.
From this, Ko and colleagues argue that Haplogroup E arose 8,000 to 11,000 years ago near the north Fujian coast, travelled to Taiwan with Neolithic settlers 6,000 years ago, and from there spread to Maritime Southeast Asia with the Austronesian language dispersal.
Soares et al caution against over-emphasizing a single sample, and maintain that a constant molecular clock implies the earlier date (and more southerly origin) remains more likely.
Distribution
Haplogroup E is found throughout Maritime Southeast Asia.
It is nearly absent from mainland East Asia, where its sister group M9a (also found in Japan) is common.
In particular, it is found among speakers of Austronesian languages, and it is rare even in Southea
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https://en.wikipedia.org/wiki/Human%20%CE%B2-globin%20locus
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The human β-globin locus is composed of five genes located on a short region of chromosome 11, responsible for the creation of the beta parts (roughly half) of the oxygen transport protein Haemoglobin. This locus contains not only the beta globin gene but also delta, gamma-A, gamma-G, and epsilon globin. Expression of all of these genes is controlled by single locus control region (LCR), and the genes are differentially expressed throughout development.
The order of the genes in the beta-globin cluster is: 5' - epsilon – gamma-G – gamma-A – delta – beta - 3'.
The arrangement of the genes directly reflects the temporal differentiation of their expression during development, with the early-embryonic stage version of the gene located closest to the LCR. If the genes are rearranged, the gene products are expressed at improper stages of development.
Expression of these genes is regulated in embryonic erythropoiesis by many transcription factors, including KLF1, which is associated with the upregulation of adult hemoglobin in adult definitive erythrocytes, and KLF2, which is vital to the expression of embryonic hemoglobin.
HBB complex
Many CRMs have been mapped within the cluster of genes encoding β-like globins expressed in embryonic (HBE1), fetal (HBG1 and HBG2), and adult (HBB and HBD) erythroid cells. All are marked by DNase I hypersensitive sites and footprints, and many are bound by GATA1 in peripheral blood derived erythroblasts (PBDEs). A DNA segment located between th
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https://en.wikipedia.org/wiki/Hemoglobin%20subunit%20beta
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Hemoglobin subunit beta (beta globin, β-globin, haemoglobin beta, hemoglobin beta) is a globin protein, coded for by the HBB gene, which along with alpha globin (HBA), makes up the most common form of haemoglobin in adult humans, hemoglobin A (HbA). It is 147 amino acids long and has a molecular weight of 15,867 Da. Normal adult human HbA is a heterotetramer consisting of two alpha chains and two beta chains.
HBB is encoded by the HBB gene on human chromosome 11. Mutations in the gene produce several variants of the proteins which are implicated with genetic disorders such as sickle-cell disease and beta thalassemia, as well as beneficial traits such as genetic resistance to malaria. At least 50 disease-causing mutations in this gene have been discovered.
Gene locus
HBB protein is produced by the gene HBB which is located in the multigene locus of β-globin locus on chromosome 11, specifically on the short arm position 15.4. Expression of beta globin and the neighbouring globins in the β-globin locus is controlled by single locus control region (LCR), the most important regulatory element in the locus located upstream of the globin genes. The normal allelic variant is 1600 base pairs (bp) long and contains three exons. The order of the genes in the beta-globin cluster is 5' - epsilon – gamma-G – gamma-A – delta – beta - 3'.
Interactions
HBB interacts with Haemoglobin, alpha 1 (HBA1) to form haemoglobin A, the major haemoglobin in adult humans. The interaction is two-fol
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https://en.wikipedia.org/wiki/Allosteric%20enzyme
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Allosteric enzymes are enzymes that change their conformational ensemble upon binding of an effector (allosteric modulator) which results in an apparent change in binding affinity at a different ligand binding site. This "action at a distance" through binding of one ligand affecting the binding of another at a distinctly different site, is the essence of the allosteric concept. Allostery plays a crucial role in many fundamental biological processes, including but not limited to cell signaling and the regulation of metabolism. Allosteric enzymes need not be oligomers as previously thought, and in fact many systems have demonstrated allostery within single enzymes.
In biochemistry, allosteric regulation (or allosteric control) is the regulation of a protein by binding an effector molecule at a site other than the enzyme's active site.
The site to which the effector binds is termed the allosteric site. Allosteric sites allow effectors to bind to the protein, often resulting in a conformational change involving protein dynamics. Effectors that enhance the protein's activity are referred to as allosteric activators, whereas those that decrease the protein's activity are called allosteric inhibitors.
Allosteric regulations are a natural example of control loops, such as feedback from downstream products or feedforward from upstream substrates. Long-range allostery is especially important in cell signaling. Allosteric regulation is also particularly important in the cell's abili
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https://en.wikipedia.org/wiki/Douglas%20Barber
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Douglas Barber, is a Canadian businessman. He is a founder and former President and CEO of Gennum Corporation, a Canadian public company that designs, manufactures and markets semiconductors and semiconductor-based products.
Early life and education
Born in Saskatchewan, Barber received a Bachelor of Science degree in 1959 and a Master of Science degree in 1960 both in Electrical Engineering from the University of Saskatchewan. He received a D.I.C. and Ph.D. in Electrical Engineering in 1965 from Imperial College London.
Career
In 1965, he started his career as a research engineer, manager at Westinghouse Canada. In 1973, he co-founded Linear Technology Inc. and was President and COO. In 1990, Linear Technology Inc. was rebranded as Gennum Corporation. Under his leadership, Gennum Corporation grew to over 500 employees, with subsidiaries in Japan and the United Kingdom. Gennum Corporation was later bought by Semtech for $500 million in 2012.
In 1968, Barber started teaching at McMaster University in the Department of Engineering Physics as a part-time Assistant Professor. He was appointed a part-time Associate Professor in 1974 and a part-time Professor in 1981. He retired in 1994.
Barber was actively involved in Microelectronics initiatives in Canada including the Canadian Semiconductor Technology Conference, the Canadian Microelectronics Corporation, the Sectoral Skills Council, the Canadian Semiconductor Design Association, Micronet and the Strategic Semiconductor C
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https://en.wikipedia.org/wiki/Distributed%20minimum%20spanning%20tree
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The distributed minimum spanning tree (MST) problem involves the construction of a minimum spanning tree by a distributed algorithm, in a network where nodes communicate by message passing. It is radically different from the classical sequential problem, although the most basic approach resembles Borůvka's algorithm. One important application of this problem is to find a tree that can be used for broadcasting. In particular, if the cost for a message to pass through an edge in a graph is significant, an MST can minimize the total cost for a source process to communicate with all the other processes in the network.
The problem was first suggested and solved in time in 1983 by Gallager et al., where is the number of vertices in the graph. Later, the solution was improved to and finally
where D is the network, or graph diameter. A lower bound on the time complexity of the solution has been eventually shown to be
Overview
The input graph is considered to be a network, where vertices are independent computing nodes and edges are communication links. Links are weighted as in the classical problem.
At the beginning of the algorithm, nodes know only the weights of the links which are connected to them. (It is possible to consider models in which they know more, for example their neighbors' links.)
As the output of the algorithm, every node knows which of its links belong to the minimum spanning tree and which do not.
MST in message-passing model
The message-passing mode
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https://en.wikipedia.org/wiki/Jazz%20Semiconductor
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Jazz Semiconductor is a semiconductor wafer foundry that is a wholly owned United States subsidiary of Israel-based Tower Semiconductor. Its customers include developers of wireless, optical networking, power management, storage, and aerospace/defense applications. Headquartered in Newport Beach, California, Jazz passed through a number of acquisitions including the short-lived company Acquicor Technology, which renamed itself Jazz Technologies and then sold it two years later.
History
Jazz Semiconductor Systems was founded on February 15, 2002, renamed itself Specialtysemi, Inc. later in February 2002 and to Jazz Semiconductor, Inc. in May 2002. Prior to March 12, 2002, it was Conexant's fabrication facility, as subsidiary Newport Fab, LLC. It was initially funded by Conexant and affiliates of the Carlyle Group. Shu Li was its chief executive since May 2002. RF Micro Devices invested $60 million in October 2002, and became a customer.
Jazz reported losses for each year of 2003, 2004, and 2005.
It filed for an attempted initial public offering (IPO) several times from January 2004 through July 2006, to be listed on Nasdaq under symbol JAZZ, but failed to attract investor interest.
Acquicor Management LLC was jointly formed by Gil Amelio, Steve Wozniak and Ellen Hancock, all of whom had worked for Apple Computer.
Founded in August 2005, Amelio was Acquicor's chief executive.
Acquicor Technology was known as a blank-check company: it existed only to make acquisitions in unsp
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https://en.wikipedia.org/wiki/Friendly%20Fa%24cism
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Friendly Fa$cism is a full-length album by industrial/hip hop artists Consolidated, released in 1991.
"Brutal Equation" and "Unity of Oppression" were alternative rock hits on MTV. The album peaked at #6 on the CMJ Radio Top 150.
The name comes from Friendly Fascism: The New Face of Power in America, the title of a 1980 book by political scientist Bertram Gross which lays out the form of "creeping fascism" that Gross feared might come to pass in the United States.
Critical reception
Trouser Press wrote that "the insufferably self-righteous tone makes the disc hard to endure." Alternative Rock called the album "a hard-hitting soundtrack of hip-hop, funk, soul, and hard rock.
Track listing (CD)
"Zero" – 0:21
"Brutal Equation" – 4:13
"Our Leader" – 1:01
"Unity Of Oppression" – 4:01
"The Sexual Politics Of Meat" – 3:43
"Typical Male" – 5:18
"Entertainment Tonight" – 0:40
"Dominion" – 4:04
"Friendly Fascism" – 5:01
"College Radio" – 1:27
"We Gotta Have Peace" – 3:30
"Meat Kills" – 3:34
"Stoned" – 6:54
"Your Body Belongs To The State" – 1:49
"Crusading Rap Guys" – 5:29
"Murder One" – 2:52
"White American Male '91 (The Truth Hurts) Part 2" – 5:12
"Music Has No Meaning" – 5:17
Track listing (Vinyl)
Side One
"Zero" – 0:21
"Brutal Equation" – 4:13
"Our Leader" – 1:01
"Unity Of Oppression" – 4:01
"The Sexual Politics Of Meat" – 3:43
"Typical Male" – 5:18
"Entertainment Tonight" – 0:40
"Friendly Fascism" – 5:01
Side Two
"We Gotta
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https://en.wikipedia.org/wiki/Echidna%20atricaudata
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Echidna atricaudata (a taxonomic synonym) may refer to:
Cerastes cerastes, a.k.a. the desert horned viper, a venomous viper native to the deserts of Northern Africa and parts of the Middle East
Cerastes vipera, a.k.a. the sahara sand viper, a venomous viper found in the deserts of North Africa and the Sinai Peninsula
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https://en.wikipedia.org/wiki/Lego%20Aquazone
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Lego Aquazone (stylized as LEGO Aquazone) was a Lego theme that was launched by The Lego Group in 1995 and discontinued in 1998. It centred on undersea miners and their enemies searching for crystals. It consisted of submarine vehicles and aquatic animals, with minifigures designed for submarine adventures.
Overview
Aquazone was a Lego product line that focused on undersea adventures. It launched in 1995 with two sub-themes named Aquanauts and Aquasharks, which were released simultaneously. This was followed by the release of three additional sub-themes: Aquaraiders in 1997, Hydronauts in 1998 and Stingrays in 1998. Aqua Raiders was launched later in 2007 as a standalone theme.
Sub-themes
Aquanauts (1995–1996)
The Aquanauts were the heroes of this sub-theme, which launched in 1995 and continued production until 1996. They were defined as a group of undersea miners. The backstory of the theme focused on the Aquanauts exploring the ocean in search of crystals to investigate their properties. Their base was called the Neptune Discovery Lab. They also used underwater vehicles, such as the Crystal Explorer Sub and the Crystal Crawler to do their work.
1728/6145 Crystal Crawler/Aquanaut Turbo Amphi
1749/1806 Hydronaut Paravane
1822 Sea Claw 7
6125 Sea Sprint 9/Aquanaut Octopod
6175 Crystal Explorer Sub/Aquanaut DSRV II
6195 Neptune Discovery Lab/Aqua Dome 7
Aquasharks (1995–1996, 1998)
The Aquasharks sub-theme was launched alongside Aquanauts in 1995 and continued
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https://en.wikipedia.org/wiki/Gary%20Locke%20%28English%20footballer%29
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Gary Robert Locke (born 12 July 1954) is an English former footballer born in Willesden, London, who played in the Football League for Chelsea and Crystal Palace, and in the Allsvenskan for Halmstads BK.
Locke was born in Park Royal but moved to Willesden as a six-year-old with his family in 1960.
A right-back, Locke spent much of his career at Chelsea, making more than 300 league and cup appearances for the west London side between 1972 and 1983. He turned professional in July 1971, made his debut in a 3–1 win against Coventry City in the First Division on 30 September 1972, and scored his first goal for the club against the same opponents on 24 August 1974. Capable of making overlapping attacking runs up the wing, he was chosen as Chelsea Player of the Year in the 1973–74 season.
In 1983, after a spell on loan at the club, he moved to Crystal Palace on a permanent basis, making another 101 league and cup appearances in total, before spending the 1986 season in Sweden with Halmstads BK.
In 1987 Locke was brought to New Zealand by newly promoted National League club Napier City Rovers. He captained the team in 1988 and helped the club win the National League championship in 1989. Locke was left out of Napier's squad for the 1992 National League campaign.
References
External links
1954 births
Living people
Footballers from Willesden
English men's footballers
Men's association football fullbacks
Chelsea F.C. players
Crystal Palace F.C. players
Halmstads BK players
Napier
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https://en.wikipedia.org/wiki/Chlorargyrite
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Chlorargyrite is the mineral form of silver chloride (AgCl). Chlorargyrite occurs as a secondary mineral phase in the oxidation of silver mineral deposits. It crystallizes in the isometric - hexoctahedral crystal class. Typically massive to columnar in occurrence it also has been found as colorless to variably yellow cubic crystals. The color changes to brown or purple on exposure to light. It is quite soft with a Mohs hardness of 1 to 2 and dense with a specific gravity of 5.55. It is also known as cerargyrite and, when weathered by desert air, as horn silver. Bromian chlorargyrite (or embolite) is also common. Chlorargyrite is water-insoluble.
It occurs associated with native silver, cerussite, iodargyrite, atacamite, malachite, jarosite and various iron–manganese oxides.
It was first described in 1875 for occurrences in the Broken Hill district, New South Wales, Australia. The rich Bridal Chamber deposit at Lake Valley, Sierra County, New Mexico was almost pure chlorargyrite. The name is from the Greek, chloros for "pale green" and Latin for silver, argentum.
See also
Bromargyrite
Iodargyrite
References
Palache, C., H. Berman, and C. Frondel (1951) Dana's system of mineralogy, (7th edition), v. II, pp. 11–15
Halide minerals
Silver minerals
Alchemical substances
Cubic minerals
Minerals in space group 225
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https://en.wikipedia.org/wiki/Phalasarna
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Phalasarna or Falasarna () is a Greek harbour town at the west end of Crete that flourished during the Hellenistic period. The currently visible remains of the city include several imposing sandstone towers and bastions, with hundreds of meters of fortification walls protecting the town, and a closed harbor, meaning it is protected on all sides by city walls. The harbor is ringed by stone quays with mooring stones, and connected to the sea through two artificial channels. Notable finds in the harbor area include public roads, wells, warehouses, an altar, and baths. Most of these structures were revealed by excavations that began in 1986.
The acropolis is built on a cape that rises 90 meters above the harbor and juts into the sea. The acropolis has many remains, including a temple dedicated to goddess Dictynna, fortification towers, cisterns, wells, and watchtowers that could have been used to guard sea routes.
Today Phalasarna is an agricultural area and tourist attraction.
The valley is filled with olive groves and greenhouses cultivating mainly tomatoes; there are also scattered family-run hotels and restaurants. The seaside has long sandy beaches and crystal clear waters that are popular both with residents of the province of Chania and visitors from Greece and abroad. Falasarna beach was voted, in a CNN poll, among the best 100 beaches of the world.
Ancient history
Phalasarna was mentioned by the ancient historians and geographers Scylax, Strabo, Polybius, Livy, Pliny
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https://en.wikipedia.org/wiki/NS%20Class%20400
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The Nederlandse Spoorwegen (NS) Class 400 was a derivative of the successful Class 200, also built for shunting duties. They were larger than their predecessors, and were built by Werkspoor from probably 1945–1956. They were called "Grote Siks" (big goats). Unlike their predecessors, they were generally unsuccessful and in 10 years were replaced by the larger Series 500 and 600.
0400
Werkspoor locomotives
B locomotives
Diesel locomotives of the Netherlands
Standard gauge locomotives of the Netherlands
Railway locomotives introduced in 1945
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https://en.wikipedia.org/wiki/Rotating%20tank
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A rotating tank is a device used for fluid dynamics experiments. Typically cylinders filled with water on a rotating platform, the tanks can be used in various ways to simulate the atmosphere or ocean.
For example, a rotating tank with an ice bucket in the center can represent the Earth, with a cold pole simulated by the ice bucket. Just as in the atmosphere, eddies and a westerly jetstream form in the water.
External links
Rotating tank experiment descriptions and movies
Fluid dynamics
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https://en.wikipedia.org/wiki/Crystal%20Range
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The Crystal Range is a small chain of mountain peaks in the Desolation Wilderness in the U.S. state of California. It is a subrange of the Sierra Nevada. The highest and most southerly peak is Pyramid Peak at 9985 ft; Mount Agassiz is next north at 9967 ft, with Mount Price (9975 ft) rounding out the southern group of peaks. Tells Peak is the northernmost named peak in the range.
It is southwest of Lake Tahoe and north of U.S. Route 50. Two main access roads run off of U.S. Route 50, Ice House Road, which is furthest west, and more easterly, Wright's Lake Road which is a steep road not conducive to trailers or large vehicles. Many access the tallest peak Pyramid Peak from Hwy 50 directly hiking in, to the Desolation Wilderness.
References
External links
The Crystal Range seen from east within the Desolation Wilderness looking over Lake Aloha, Pyramid Peak on the left.
Mountains of the Desolation Wilderness
Mountain ranges of Northern California
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https://en.wikipedia.org/wiki/Mondo%20Topless
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Mondo Topless is a 1966 pseudo-documentary directed by Russ Meyer, featuring Babette Bardot and Lorna Maitland among others. It was Meyer's first color film following a string of black and white "roughie nudies", including Faster, Pussycat! Kill! Kill! While a straightforward sexploitation film, the film owes some debt to the French New Wave and cinéma vérité traditions, and is known to some under the titles Mondo Girls and Mondo Top.
Its tagline: "Two Much For One Man...Russ Meyer's Busty Buxotic Beauties ... Titilating ... Torrid ... Untopable ... Too Much For One Man!"
The film was banned in Finland.
Plot
The film presents a snapshot of '60s San Francisco before shifting its focus to strippers. The strippers' lives are earnestly portrayed as they reveal the day-to-day realities of sex work, talk bra sizes, relate their preferences in men, all voiced over while dancing topless to a '60s instrumental rock soundtrack. Throughout a large portion of the film, the narrator talks about the women as if they are a subgenre of the counter culture movement, somewhat similar to the beatnik or hippie movements that were highly prevalent during the same era. The "Topless" movement as it is called by the narrator could also be perceived as an allegorical subset of the Sexual Revolution of the 1960s.
Cast
Babette Bardot as Bouncy
Pat Barrington as Herself (as Pat Barringer)
Sin Lenee as Lucious
Darlene Gray as Buxotic
Diane Young as Yummy
Darla Paris as Delicious
Donna X as
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https://en.wikipedia.org/wiki/CJIJ-FM
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CJIJ-FM (branded as C99 FM) was a Canadian radio station, broadcasting in FM stereo at a frequency of 99.9 MHz from Membertou, Nova Scotia, a First Nations community near Sydney. CJIJ plays a variety of rock music.
The station received CRTC approval in 2002 and went on the air in 2003.
On January 29, 2021 Membertou Radio Association Inc. requested to the CRTC a voluntary revocation of their license, which was carried out on February 22, 2021.
References
External links
CJIJ-FM Facebook
Jij
Radio stations established in 2003
Radio stations disestablished in 2021
2003 establishments in Nova Scotia
2021 disestablishments in Nova Scotia
Membertou First Nation
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https://en.wikipedia.org/wiki/Fleming%E2%80%93Viot%20process
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In probability theory, a Fleming–Viot process (F–V process) is a member of a particular subset of probability measure-valued Markov processes on compact metric spaces, as defined in the 1979 paper by Wendell Helms Fleming and Michel Viot. Such processes are martingales and diffusions.
The Fleming–Viot processes have proved to be important to the development of a mathematical basis for the theories behind allele drift.
They are generalisations of the Wright–Fisher process and arise as infinite population limits of suitably rescaled variants of Moran processes.
See also
Coalescent theory
Voter model
References
Fleming, W. H., Michel Viot, M. (1979) "Some measure-valued Markov processes in population genetics theory" (PDF format) Indiana University Mathematics Journal, 28 (5), 817–843.
Ferrari, Pablo A.; Mari, Nevena "Quasi stationary distributions and Fleming Viot processes" , Lecture presentation
Markov processes
Statistical genetics
Martingale theory
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https://en.wikipedia.org/wiki/Yoshiki%20Kuramoto
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(born 1940) is a Japanese physicist in the Nonlinear Dynamics group at Kyoto University who formulated the Kuramoto model and is also known for the Kuramoto–Sivashinsky equation. He is also the discoverer of so-called chimera states in networks of coupled oscillators.
Kuramoto specializes in nonlinear dynamics (also known as nonlinear science) and non-equilibrium statistical mechanics. Notably, he has worked on the network dynamics created by limit cycle oscillators. Among his accomplishments is the derivation of the Kuramoto–Sivashinsky equation, which describes the phase instability of oscillating fields. This is regarded as the first example of spatiotemporal chaos. Another achievement is his proposal of a solvable model for oscillator populations, now known as the Kuramoto model. Other achievements include deriving the complex Ginzburg–Landau equation in reaction-diffusion systems and studying the entrainment phenomenon in coupled oscillator systems.
Biography
He was born in Osaka.
He holds a Doctor of Science degree from Kyoto University (1970). He is currently an emeritus professor of Kyoto University and a visiting professor at the Research Institute for Mathematical Sciences, Kyoto University.
Kuramoto was a student of Kazuhisa Tomita and Hajime Mori. Originally, he studied the statistical mechanics of phase transitions, but he began researching nonlinear dynamics due to doubts about the research on dissipative structures by Ilya Prigogine and others, who rece
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https://en.wikipedia.org/wiki/Cox%20process
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In probability theory, a Cox process, also known as a doubly stochastic Poisson process is a point process which is a generalization of a Poisson process where the intensity that varies across the underlying mathematical space (often space or time) is itself a stochastic process. The process is named after the statistician David Cox, who first published the model in 1955.
Cox processes are used to generate simulations of spike trains (the sequence of action potentials generated by a neuron), and also in financial mathematics where they produce a "useful framework for modeling prices of financial instruments in which credit risk is a significant factor."
Definition
Let be a random measure.
A random measure is called a Cox process directed by , if is a Poisson process with intensity measure .
Here, is the conditional distribution of , given .
Laplace transform
If is a Cox process directed by , then has the Laplace transform
for any positive, measurable function .
See also
Poisson hidden Markov model
Doubly stochastic model
Inhomogeneous Poisson process, where λ(t) is restricted to a deterministic function
Ross's conjecture
Gaussian process
Mixed Poisson process
References
Notes
Bibliography
Cox, D. R. and Isham, V. Point Processes, London: Chapman & Hall, 1980
Donald L. Snyder and Michael I. Miller Random Point Processes in Time and Space Springer-Verlag, 1991 (New York) (Berlin)
Poisson point processes
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https://en.wikipedia.org/wiki/Okorokov%20effect
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The Okorokov effect () or resonant coherent excitation, occurs when heavy ions move in crystals under channeling conditions. V. Okorokov predicted this effect in 1965 and it was first observed by Sheldon Datz in 1978.
References
Charge carriers
Ions
Physical chemistry
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https://en.wikipedia.org/wiki/Yellow%20jersey%20statistics
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Since the first Tour de France in 1903, there have been 2,205 stages, up to and including the final stage of the 2021 Tour de France. Since 1919, the race leader following each stage has been awarded the yellow jersey ().
Although the leader of the classification after a stage gets a yellow jersey, he is not considered the winner of the yellow jersey, only the wearer. Only after the final stage, the wearer of the yellow jersey is considered the winner of the yellow jersey, and thereby the winner of the Tour de France.
In this article first-place-classifications before 1919 are also counted as if a yellow jersey was awarded. There have been more yellow jerseys given than there were stages: In 1914, 1929, and 1931, there were multiple cyclists with the same leading time, and the 1988 Tour de France had a "prelude", an extra stage for a select group of cyclists. As of 2021 a total of 2,208 yellow jerseys have been awarded in the Tour de France to 295 riders.
Individual records
In previous tours, sometimes a stage was broken in two (or three). On such occasions, only the cyclist leading at the end of the day is counted. The "Jerseys" column lists the number of days that the cyclist wore the yellow jersey; the "Tour wins" column gives the number of times the cyclist won the general classification. The next four columns indicate the number of times the rider won the points classification, the King of the Mountains classification, and the young rider competition, and the years i
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https://en.wikipedia.org/wiki/Polysaccharide%20peptide
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Polysaccharide peptide (PSP) is a protein-bound polysaccharide extracted from the edible mushroom Coriolus versicolor. PSP is currently in the animal-testing phase of research in many countries for use as an anti-tumor drug. It appears to work as a biological response modifier (BRM), enhancing the body's own use of macrophages and T-lymphocytes, rather than directly attacking any tumors.
Polysaccharide Krestin (PSK) was first isolated in Japan in the late 1960s while PSP was isolated about 1983 in China. Each compound has shown remarkable anticancer properties with few side effects. By 1987 PSK accounted for more than 25% of total national expenditure for anticancer agents in Japan.
See also
Polysaccharide-K
References
Organic polymers
Polysaccharides
Oncology
Medicinal fungi
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https://en.wikipedia.org/wiki/Solar%20eclipses%20on%20Mars
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The two moons of Mars, Phobos and Deimos, are much smaller than Earth's Moon, greatly reducing the frequency of solar eclipses on that planet. Neither moon's apparent diameter is large enough to cover the disk of the Sun, and therefore they are annular solar eclipses and can also be considered transits.
Eclipses caused by Phobos
Due to the small size of Phobos (about ) and its rapid orbital motion, an observer on the surface of Mars would never experience a solar eclipse for longer than about thirty seconds. Phobos also takes only 7 hours 39 minutes to orbit Mars, while a Martian day is 24 hours 37 minutes long, meaning that Phobos can create two eclipses per Martian day. These are annular eclipses, because Phobos is not quite large enough or close enough to Mars to create a total solar eclipse. The highest resolution, highest frame rate video of a Phobos transit has been recently released from the Mastcam-Z on Perseverance rover https://www.jpl.nasa.gov/news/nasas-perseverance-rover-captures-video-of-solar-eclipse-on-mars.
Transits caused by Deimos
Deimos is too small (about ) and too far from Mars to cause an eclipse. The best an observer on Mars would see is a small spot crossing the Sun's disc.
View from Earth
Both moons are too small to cast a shadow on Mars that can be seen from Earth. However, shortly after the first artificial satellites were placed in orbit around Mars, the shadow of Phobos was seen in pictures transmitted to Earth.
One of these photos was fr
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https://en.wikipedia.org/wiki/Hydroxybenzotriazole
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Hydroxybenzotriazole (abbreviated HOBt) is an organic compound that is a derivative of benzotriazole. It is a white crystalline powder, which as a commercial product contains some water (~11.7% wt as the HOBt monohydrate crystal). Anhydrous HOBt is explosive.
It is mainly used to suppress the racemization of single-enantiomer chiral molecules and to improve the efficiency of peptide synthesis.
Use in peptide synthesis
Automated peptide synthesis involves the condensation of the amino group of protected amino acids with the activated ester. HOBt is used to produce such activated esters. These esters are insoluble (like the N-hydroxysuccinimide esters) and react with amines at ambient temperature to give amides.
HOBt is also used for the synthesis of amides from carboxylic acids aside from amino acids. These substrates may not be convertible to the acyl chlorides. For instance amide derivatives of ionophoric antibiotics have been prepared in this way.
Safety
Due to reclassification as UN0508, a class 1.3C explosive, hydroxybenzotriazole and its monohydrate crystal are no longer allowed to be transported by sea or air as per 49CFR (USDOT hazardous materials regulations). However, UNECE draft proposal ECE/TRANS/WP.15/AC.1/HAR/2009/1 has been circulated to UN delegates and, if implemented, would amend current regulations thus allowing for the monohydrate crystal to be shipped under the less-stringent code of UN3474 as a class 4.1 desensitized explosive.
References
Peptide
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https://en.wikipedia.org/wiki/Riva%20Aquarama
|
The Riva Aquarama is a luxury wooden runabout built by Italian yachtbuilder Riva. Production of it and its derivatives (the Lungo, Super, and Special) ran from 1962 until 1996. The hull was based on the Riva Tritone, an earlier model speedboat by Riva, which in turn was inspired by the American mahogany Chris-Craft runabouts. The boat's speed, beauty, and craftsmanship earned it praise as the Ferrari of the boat world. The company was founded by Pietro Riva in 1842, and run by Carlo Riva through its 1969 sale to the American Whittaker Corporation.
Description
The most famous of Carlo Riva's designs, the Aquarama has gained over the decades a legendary nautical reputation. Its evocative name, derived in part from the widescreen Cinerama movie format popular in the early 1960s, echoed in its sweeping wrap-around windshield, conjures images from another time.
The Riva Aquarama's 8.02 - 8.78 metre hull was sheathed in mahogany and varnished to accentuate the beauty of its natural wood grain. All versions were twin engined, with top speeds of 45/50 knots depending on engine choice. Power varied from 185 hp to 400 hp per engine, delivered by Riva 'tuned' Cadillac and Chrysler models, among others. On top of the engine compartment was a cushioned sundeck. The boats also carried a convertible roof which retracted behind the rear seat and cockpit. A swim ladder was often mounted in the stern.
Model variants: 1960s and 1970s
Aquarama (1962–1972) Total built 281
Aquarama Lungo (
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https://en.wikipedia.org/wiki/Duggan%E2%80%93Schwartz%20theorem
|
The Duggan–Schwartz theorem (named after John Duggan and Thomas Schwartz) is a result about voting systems designed to choose a nonempty set of winners from the preferences of certain individuals, where each individual ranks all candidates in order of preference. It states that for three or more candidates, at least one of the following must hold:
The system is not anonymous (some voters are treated differently from others).
The system is imposed (some candidates can never win).
Every voter's top preference is in the set of winners.
The system can be manipulated by either an optimistic voter, one who can cast a ballot that would elect some candidate to a higher rank than all of those candidates who would have been elected if that voter had voted honestly; or by a pessimistic voter, one who can cast a ballot that would exclude some candidate to a lower rank than all of those candidates who were elected due that voter voting strategically.
The first two conditions are considered forbidden in any fair election, and the third condition requires many candidates to "tie" for the win. The general conclusion, then, is the same as that usually given to the Gibbard–Satterthwaite theorem: voting systems can be manipulated. The result essentially holds even if ties are allowed in the ballots; in that case, there exists at least one "weak dictator" such that at least one of the candidates tied at the top of that voter's ballot is a winner.
The Gibbard–Satterthwaite theorem is a similar
|
https://en.wikipedia.org/wiki/Normal%20curve%20equivalent
|
In educational statistics, a normal curve equivalent (NCE), developed for the United States Department of Education by the RMC Research Corporation, is a way of normalizing scores received on a test into a 0-100 scale similar to a percentile rank, but preserving the valuable equal-interval properties of a z-score.
It is defined as:
70770 + /qnorm(.99) × z
or, approximately
50 + 21.063 × z,
where z is the standard score or "z-score", i.e. z is how many standard deviations above the mean the raw score is (z is negative if the raw score is below the mean). The reason for the choice of the number 21.06 is to bring about the following result: If the scores are normally distributed (i.e. they follow the "bell-shaped curve") then
the normal equivalent score is 99 if the percentile rank of the raw score is 99;
the normal equivalent score is 50 if the percentile rank of the raw score is 50;
the normal equivalent score is 1 if the percentile rank of the raw score is 1.
This relationship between normal equivalent scores and percentile ranks does not hold at values other than 1, 50, and 99. It also fails to hold in general if scores are not normally distributed.
The number 21.06 was chosen because
It is desired that a score of 99 correspond to the 99th percentile;
The 99th percentile in a normal distribution is 2.3263 standard deviations above the mean;
99 is 49 more than 50—thus 49 points above the mean;
49/2.3263 = 21.06.
Normal curve equivalents are on an equal-int
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https://en.wikipedia.org/wiki/Joel%20Rosenbaum
|
Joel Rosenbaum (born October 4, 1933) is a professor of cell biology at Yale University.
Rosenbaum received his bachelor's degree from Syracuse University in 1955, and later his M.Sc. Ed. from St. Lawrence University in 1957. He returned later to Syracuse for his master's degree in 1959 and Ph.D. in 1963.
His lab at Yale studies cilia and flagella, small tail-like organelles, using the model species Chlamydomonas, a single-cell alga. The lab is best known for its discovery of intraflagellar transport, a vital molecular process now linked to many human diseases, in 1993. Rosenbaum has continued to pursue intraflagellar transport as his main research interest.
Rosenbaum received the E.B. Wilson Medal from the ASCB in 2006, the highest award given in the field of cell biology.
References
External links
"Joel Rosenbaum," member profile from the American Society for Cell Biology website. Retrieved October 31, 2007.
21st-century American biologists
Yale University faculty
Syracuse University alumni
Living people
1933 births
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https://en.wikipedia.org/wiki/Four-Phase%20Systems
|
Four-Phase Systems was a computer company, founded by Lee Boysel and others, which built one of the earliest computers using semiconductor main memory and MOS LSI logic. The company was incorporated in February 1969 and had moderate commercial success. It was acquired by Motorola in 1981.
History
The idea behind Four-Phase Systems began when Boysel was designing MOS components at Fairchild Semiconductor in 1967. Boysel wrote a manifesto explaining how a computer could be built from a small number of MOS chips. Fairchild made Boysel head of a MOS design group, which he used to design parts satisfying the requirements of his putative computer. After doing this, Boysel left to start Four-Phase in October 1968, initially with two other engineers from his Fairchild group as well as others. Boysel was not sued by Fairchild, perhaps because of chaos caused by a change in Fairchild management at that time. When the company was incorporated in February 1969, he was joined by other engineers from the Fairchild group. Robert Noyce, co-founder of Intel, was an early board member.
Boysel arranged for chips to be fabricated by Cartesian, a wafer-processing company founded by another engineer from Fairchild. Four-Phase showed its system at the Fall Joint Computer Conference in 1970. By June 1971, Four-Phase IV/70 computers were in use at four different customers, and by March 1973, they had shipped 347 systems to 131 customers. The company enjoyed a substantial level of success
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https://en.wikipedia.org/wiki/Transport%20in%20Winnipeg
|
Transport in Winnipeg involves various transportation systems, including both private and public services, and modes of transport in the capital city of Manitoba.
According to Statistics Canada, in 2011, the dominant form of travel in Winnipeg was by car as a driver (69%), followed by commute trips using public transit (15%), as a car passenger (7%), walking (6%), bicycle (2%), and other modes (1%).
In the province of Manitoba, transportation is the largest contributor to greenhouse gas emissions, representing almost half of the personal emissions for households. As such, the City of Winnipeg government aims for its residents to ultimately adopt sustainable transport methods—i.e., walking, cycling, and public transit—as their preferred choice of transportation.
Transportation structures within the city are the responsibility of the Winnipeg government's Public Works Department. More generally, transportation in Manitoba is regulated by The Driver and Vehicles Act and The Highway Traffic Act. Moreover, insurance is mandatory in the province, and is made available via Manitoba Public Insurance and Autopac brokers.
Pre-incorporation
For thousands of years, the region's Indigenous peoples used various networks of rivers across what is now known as the province of Manitoba.
Situated at the confluence of the Red and the Assiniboine rivers in what is now downtown Winnipeg, The Forks became an early meeting place for the purpose of trade and would prove to be the most important
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https://en.wikipedia.org/wiki/U.S.%20Coast%20Guard%20environmental%20protection
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Marine environmental protection is one of the eleven missions of the United States Coast Guard (USCG).
Protecting the delicate ecosystem of oceans is a vital Coast Guard mission. The Coast Guard works with a variety of groups and organizations to ensure the livelihood of endangered marine species.
Through the Marine Environmental Protection program (MEP), the Coast Guard develops and enforces regulations to avert the introduction of invasive species into the maritime environment, stop unauthorized ocean dumping, and prevent oil and chemical spills.
There are five areas of emphasis for MEPs mission. These areas cover virtually every aspect of oil and chemical response, and provide the goals and objectives for Coast Guard initiatives.
The five areas are:
Prevention
To stop pollution before it occurs, with:
Training
Equipment
Procedures
Enforcement
To provide civil and criminal penalties for illegal acts
Surveillance
To protect the marine environment by conducting:
Pollution overflights
Vessel boardings
Harbor patrols
Transfer monitoring
Facility inspections
Response
Cleanup and impact limitation of an oil or chemical discharge
In-house abatement
Ensure that Coast Guard vessels and facilities comply with federal pollution laws and regulations
References
External links
United States Coast Guard
Ocean pollution
Environmental protection agencies
Environmental agencies in the United States
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https://en.wikipedia.org/wiki/X-Fab
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The X-FAB Silicon Foundries is a group of semiconductor foundries. The group specializes in the fabrication of analog and mixed-signal integrated circuits for fabless semiconductor companies, as well as MEMS and solutions for high voltage applications. The holding company named "X-FAB Silicon Foundries SE" is based in Tessenderlo, Belgium while its headquarters is located in Erfurt, Germany.
History
As a result of the German reunification in the 1990s, came to the dismantling of the old electronics conglomerate in East Germany named Kombinat Mikroelektronik Erfurt. The conglomerate was privatized in 1992 and divided into X-FAB Gesellschaft zur Fertigung von Wafern mbH (simply known as X-Fab) and the Thesys Gesellschaft für Mikroelektronik mbH (simply known as Thesys). X-Fab would be majority owned by the company while Thesys would be majority owned by the German state of Thuringia.
In 1999, X-Fab acquired a foundry from Texas Instruments in Lubbock, Texas, USA. In the same year, X-Fab (at this time owned by Belgian holding company named Elex N.V) acquired Thesys and disposed of its non-foundry business.
In 2002, X-Fab acquired Zarlink wafer plant in Plymouth, United Kingdom.
In 2006, X-Fab merged with 1st Silicon, a semiconductor fabrication plant located in Sarawak, Malaysia. The Sarawak government acquired 35% of X-Fab shares in the merger.
In 2007, X-Fab acquired the foundry business from ZMD, thus enabling ZMD to focus on its core business of design and developing
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https://en.wikipedia.org/wiki/Rectified%20120-cell
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In geometry, a rectified 120-cell is a uniform 4-polytope formed as the rectification of the regular 120-cell.
E. L. Elte identified it in 1912 as a semiregular polytope, labeling it as tC120.
There are four rectifications of the 120-cell, including the zeroth, the 120-cell itself. The birectified 120-cell is more easily seen as a rectified 600-cell, and the trirectified 120-cell is the same as the dual 600-cell.
Rectified 120-cell
In geometry, the rectified 120-cell or rectified hecatonicosachoron is a convex uniform 4-polytope composed of 600 regular tetrahedra and 120 icosidodecahedra cells. Its vertex figure is a triangular prism, with three icosidodecahedra and two tetrahedra meeting at each vertex.
Alternative names:
Rectified 120-cell (Norman Johnson)
Rectified hecatonicosichoron / rectified dodecacontachoron / rectified polydodecahedron
Icosidodecahedral hexacosihecatonicosachoron
Rahi (Jonathan Bowers: for rectified hecatonicosachoron)
Ambohecatonicosachoron (Neil Sloane & John Horton Conway)
Projections
Related polytopes
Notes
References
Kaleidoscopes: Selected Writings of H. S. M. Coxeter, edited by F. Arthur Sherk, Peter McMullen, Anthony C. Thompson, Asia Ivic Weiss, Wiley-Interscience Publication, 1995,
(Paper 22) H.S.M. Coxeter, Regular and Semi-Regular Polytopes I, [Math. Zeit. 46 (1940) 380-407, MR 2,10]
(Paper 23) H.S.M. Coxeter, Regular and Semi-Regular Polytopes II, [Math. Zeit. 188 (1985) 559-591]
(Paper 24) H.S.M. Coxeter, Regular and
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https://en.wikipedia.org/wiki/Geodesics%20as%20Hamiltonian%20flows
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In mathematics, the geodesic equations are second-order non-linear differential equations, and are commonly presented in the form of Euler–Lagrange equations of motion. However, they can also be presented as a set of coupled first-order equations, in the form of Hamilton's equations. This latter formulation is developed in this article.
Overview
It is frequently said that geodesics are "straight lines in curved space". By using the Hamilton–Jacobi approach to the geodesic equation, this statement can be given a very intuitive meaning: geodesics describe the motions of particles that are not experiencing any forces. In flat space, it is well known that a particle moving in a straight line will continue to move in a straight line if it experiences no external forces; this is Newton's first law. The Hamiltonian describing such motion is well known to be with p being the momentum. It is the conservation of momentum that leads to the straight motion of a particle. On a curved surface, exactly the same ideas are at play, except that, in order to measure distances correctly, one must use the Riemannian metric. To measure momenta correctly, one must use the inverse of the metric. The motion of a free particle on a curved surface still has exactly the same form as above, i.e. consisting entirely of a kinetic term. The resulting motion is still, in a sense, a "straight line", which is why it is sometimes said that geodesics are "straight lines in curved space". This idea is developed
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https://en.wikipedia.org/wiki/Helix%20bundle
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A helix bundle is a small protein fold composed of several alpha helices that are usually nearly parallel or antiparallel to each other.
Three-helix bundles
Three-helix bundles are among the smallest and fastest known cooperatively folding structural domains. The three-helix bundle in the villin headpiece domain is only 36 amino acids long and is a common subject of study in molecular dynamics simulations because its microsecond-scale folding time is within the timescales accessible to simulation. The 40-residue HIV accessory protein has a very similar fold and has also been the subject of extensive study. There is no general sequence motif associated with three-helix bundles, so they cannot necessarily be predicted from sequence alone. Three-helix bundles often occur in actin-binding proteins and in DNA-binding proteins.
Four-helix bundles
Four-helix bundles typically consist of four helices packed in a coiled-coil arrangement with a sterically close-packed hydrophobic core in the center. Pairs of adjacent helices are often additionally stabilized by salt bridges between charged amino acids. The helix axes typically are oriented about 20 degrees from their neighboring helices, a much shallower incline than in the larger helical structure of the globin fold.
The specific topology of the helices is dependent on the protein – helices that are adjacent in sequence are often antiparallel, although it is also possible to arrange antiparallel links between two pairs of parallel
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https://en.wikipedia.org/wiki/Villin-1
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Villin-1 is a 92.5 kDa tissue-specific actin-binding protein associated with the actin core bundle of the brush border. Villin-1 is encoded by the VIL1 gene. Villin-1 contains multiple gelsolin-like domains capped by a small (8.5 kDa) "headpiece" at the C-terminus consisting of a fast and independently folding three-helix bundle that is stabilized by hydrophobic interactions. The headpiece domain is a commonly studied protein in molecular dynamics due to its small size and fast folding kinetics and short primary sequence.
Structure
Villin-1 is made up of seven domains, six homologous domains make up the N-terminal core and the remaining domain makes up the C-terminal cap. Villin contains three phosphatidylinositol 4,5-biphosphate (PIP2) binding sites, one of which is located at the head piece and the other two in the core. The core domain is approximately 150 amino acid residues grouped in six repeats. On this core is an 87 residue, hydrophobic, C-terminal headpiece
The headpiece (HP67) is made up of a compact, 70 amino acid folded protein at the C-terminus. This headpiece contains an F-actin binding domain. Residues K38, E39, K65, 70-73:KKEK, G74, L75 and F76 surround a hydrophobic core and are believed to be involved in the binding of F-actin to villin-1. Residues E39 and K70 form a salt bridge buried within the headpiece which serves to connect N and C terminals. This salt bridge may also orient and fix the C-terminal residues involved in F-actin binding as in the
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https://en.wikipedia.org/wiki/Rop%20protein
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Rop (also known as repressor of primer, or as RNA one modulator (ROM)) is a small dimeric protein responsible for keeping the copy number of ColE1 family and related bacterial plasmids low in E. coli by increasing the speed of pairing between the preprimer RNA, RNA II, and its antisense RNA, RNA I. Structurally, Rop is a homodimeric four-helix bundle protein formed by the antiparallel interaction of two helix-turn-helix monomers. The Rop protein's structure has been solved to high resolution. Due to its small size and known structure, Rop has been used in protein design work to rearrange its helical topology and reengineer its loop regions. In general, the four-helix bundle has been extensively used in de novo protein design work as a simple model to understand the relationship between amino acid sequence and structure.
External links
Rop protein from Proteopedia
References
Proteins
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https://en.wikipedia.org/wiki/Richard%20Sears%20McCulloh
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Richard Sears McCulloh (18 March 1818 – 1894) was an American civil engineer and professor of mechanics and thermodynamics at the Washington and Lee University, Lexington, Virginia.
Career
McCulloh was born on 18 March 1818 in Baltimore, Maryland, United States.
He graduated from the College of New Jersey in 1836, then studied chemistry in Philadelphia with James Curtis Booth from 1838 to 1839.
From 1846 to 1849 he worked for the U.S. Mint in Philadelphia.
He was elected to the American Philosophical Society in 1846. McCulloh was appointed professor of natural philosophy at Princeton University on 24 October 1849, and then professor of natural and experimental philosophy at Columbia College on 3 April 1854.
During the American Civil War, McCulloh disappeared from New York after the draft riots and in October 1863 McCulloh went to Richmond, Virginia to become the consulting chemist of the Confederate Nitre and Mining Bureau.
In response, Columbia College expelled him from his professorship.
While in Richmond, he helped "the Confederacy in making a chemical weapon".
His experiments in creating a lethal gas were proved successful in February 1865, but before the weapon could be used in practice Richmond fell in April 1865. McCulloh fled the city but was captured two months later off the coast of Florida, and for almost two years was imprisoned in the Virginia State Penitentiary.
After being released, in 1866 McCulloh was appointed to the new "McCormick Professorship of Exper
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https://en.wikipedia.org/wiki/TNF%20receptor%20superfamily
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The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis factors (TNFs) via an extracellular cysteine-rich domain. With the exception of nerve growth factor (NGF), all TNFs are homologous to the archetypal TNF-alpha. In their active form, the majority of TNF receptors form trimeric complexes in the plasma membrane. Accordingly, most TNF receptors contain transmembrane domains (TMDs), although some can be cleaved into soluble forms (e.g. TNFR1), and some lack a TMD entirely (e.g. DcR3). In addition, most TNF receptors require specific adaptor protein such as TRADD, TRAF, RIP and FADD for downstream signalling. TNF receptors are primarily involved in apoptosis and inflammation, but they can also take part in other signal transduction pathways, such as proliferation, survival, and differentiation. TNF receptors are expressed in a wide variety of tissues in mammals, especially in leukocytes.
The term death receptor refers to those members of the TNF receptor superfamily that contain a death domain, such as TNFR1, Fas receptor, DR4 and DR5. They were named after the fact that they seemed to play an important role in apoptosis (programmed cell death), although they are now known to play other roles as well.
In the strict sense, the term TNF receptor is often used to refer to the archetypal members of the superfamily, namely TNFR1 and TNFR2, which recognize TNF-alpha.
Members
There a
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https://en.wikipedia.org/wiki/Mark%20Pinsky
|
Mark A. Pinsky (15 July 1940 – 8 December 2016) was Professor of Mathematics at Northwestern University. His research areas included probability theory, mathematical analysis, Fourier Analysis and wavelets. Pinsky earned his Ph.D at Massachusetts Institute of Technology (MIT).
His published works include 125 research papers and ten books, including several conference proceedings and textbooks. His 2002 book, Introduction to Fourier Analysis and Wavelets, has been translated into Spanish.
Biography
Pinsky was at Northwestern beginning in 1968, following a two-year postdoctoral position at Stanford. He completed the Ph.D. at Massachusetts Institute of Technology in 1966, under the direction of Henry McKean and became Full Professor in 1976. He was married to the artist Joanna Pinsky since 1963; they have three children, Seth, Jonathan and Lea, and four grandchildren, Nathan, Jason, Justin and Jasper.
Academic memberships and services
Pinsky was a member of the American Mathematical Society (AMS), a fellow of the Institute of Mathematical Statistics, Mathematical Association of America, and has provided services for Mathematical Sciences Research Institute (MSRI), most recently as Consulting Editor for the AMS. He served on the Executive Committee of MSRI for the period 1996–2000.
Pinsky was an invited speaker at the meeting to honor Stanley Zietz in Philadelphia at University of the Sciences in Philadelphia, on 20 March 2008.
Pinsky was a Fellow of the Institute of Mat
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https://en.wikipedia.org/wiki/Millay
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Millay may refer to:
People
Diana Millay (1940-2021), American actress
Edna St. Vincent Millay (1892–1950), American lyrical poet and playwright
George Millay (1929–2006), American businessman
Tamara Millay (born 1967), Missouri politician
Fictional characters
Millay, a character in the role playing game Suikoden IV
Maeve Millay, a character in the TV series Westworld
Places
Millay, Nièvre, a commune in the Nièvre department of France
Organizations
Millay Colony for the Arts, an artists' colony in Austerlitz, NY
Edna St. Vincent Millay Society, which holds the intellectual rights to the poet's work and runs Steepletop, the poet's house museum, in Austerlitz, New York
See also
Millais (disambiguation)
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https://en.wikipedia.org/wiki/Departure%20function
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In thermodynamics, a departure function is defined for any thermodynamic property as the difference between the property as computed for an ideal gas and the property of the species as it exists in the real world, for a specified temperature T and pressure P. Common departure functions include those for enthalpy, entropy, and internal energy.
Departure functions are used to calculate real fluid extensive properties (i.e. properties which are computed as a difference between two states). A departure function gives the difference between the real state, at a finite volume or non-zero pressure and temperature, and the ideal state, usually at zero pressure or infinite volume and temperature.
For example, to evaluate enthalpy change between two points h(v1,T1) and h(v2,T2) we first compute the enthalpy departure function between volume v1 and infinite volume at T = T1, then add to that the ideal gas enthalpy change due to the temperature change from T1 to T2, then subtract the departure function value between v2 and infinite volume.
Departure functions are computed by integrating a function which depends on an equation of state and its derivative.
General expressions
General expressions for the enthalpy H, entropy S and Gibbs free energy G are given by
Departure functions for Peng–Robinson equation of state
The Peng–Robinson equation of state relates the three interdependent state properties pressure P, temperature T, and molar volume Vm. From the state properties (P, V
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https://en.wikipedia.org/wiki/Basis%20trading
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Basis trading is a financial trading strategy which consists of the purchase of a particular financial instrument or commodity and the sale of its related derivative (for example the purchase of a particular bond and the sale of a related futures contract).
Basis trading is done when the investor feels that the two instruments are mispriced relative to one other and that the mispricing will correct itself so that the gain on one side of the trade will more than cancel out the loss on the other side of the trade. In the case of such a trade taking place on a security and its related futures contract, the trade will be profitable if the purchase price plus the net cost of carry is less than the futures price.
Basis of futures
Basis can be defined as the difference between the spot price of a given cash market asset and the price of its related futures contract. There will be a different basis for each delivery month for each contract. Usually, basis is defined as cash price minus futures price, however, the alternative definition, future price minus cash, is also used. A basis trade profits from the closing of an unwarranted gap between the futures contract and the associated cash market instrument.
See also
Basis swap
References
Derivatives (finance)
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https://en.wikipedia.org/wiki/MBD1
|
Methyl-CpG-binding domain protein 1 is a protein that in humans is encoded by the MBD1 gene. The protein encoded by MBD1 binds to methylated sequences in DNA, and thereby influences transcription. It binds to a variety of methylated sequences, and appears to mediate repression of gene expression. It has been shown to play a role in chromatin modification through interaction with the histone H3K9 methyltransferase SETDB1. H3K9me3 is a repressive modification.
Function
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich (CXXC) domains, and some differences in the COOH terminus. All five transcript variants repress transcription from methylated promoters; in addition, variants with three CXXC domains also repress unmethylated promoter activity. MBD1 and MBD2 map very close to each other on chromosome 18q21.
Interactions
MBD1 has been shown to interact with ATF7IP, CBX5, CHAF1A and SUV39H1.
References
Fu
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https://en.wikipedia.org/wiki/Faug%C3%A8re%27s%20F4%20and%20F5%20algorithms
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In computer algebra, the Faugère F4 algorithm, by Jean-Charles Faugère, computes the Gröbner basis of an ideal of a multivariate polynomial ring. The algorithm uses the same mathematical principles as the Buchberger algorithm, but computes many normal forms in one go by forming a generally sparse matrix and using fast linear algebra to do the reductions in parallel.
The Faugère F5 algorithm first calculates the Gröbner basis of a pair of generator polynomials of the ideal. Then it uses this basis to reduce the size of the initial matrices of generators for the next larger basis:
If Gprev is an already computed Gröbner basis (f2, …, fm) and we want to compute a Gröbner basis of (f1) + Gprev then we will construct matrices whose rows are m f1 such that m is a monomial not divisible by the leading term of an element of Gprev.
This strategy allows the algorithm to apply two new criteria based on what Faugère calls signatures of polynomials. Thanks to these criteria, the algorithm can compute Gröbner bases for a large class of interesting polynomial systems, called regular sequences, without ever simplifying a single polynomial to zero—the most time-consuming operation in algorithms that compute Gröbner bases. It is also very effective for a large number of non-regular sequences.
Implementations
The Faugère F4 algorithm is implemented
in FGb, Faugère's own implementation, which includes interfaces for using it from C/C++ or Maple,
in Maple computer algebra system, as th
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https://en.wikipedia.org/wiki/Elongation%20factor
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Elongation factors are a set of proteins that function at the ribosome, during protein synthesis, to facilitate translational elongation from the formation of the first to the last peptide bond of a growing polypeptide. Most common elongation factors in prokaryotes are EF-Tu, EF-Ts, EF-G. Bacteria and eukaryotes use elongation factors that are largely homologous to each other, but with distinct structures and different research nomenclatures.
Elongation is the most rapid step in translation. In bacteria, it proceeds at a rate of 15 to 20 amino acids added per second (about 45-60 nucleotides per second). In eukaryotes the rate is about two amino acids per second (about 6 nucleotides read per second). Elongation factors play a role in orchestrating the events of this process, and in ensuring the high accuracy translation at these speeds.
Nomenclature of homologous EFs
In addition to their cytoplasmic machinery, eukaryotic mitochondria and plastids have their own translation machinery, each with their own set of bacterial-type elongation factors. In humans, they include TUFM, TSFM, GFM1, GFM2, GUF1; the nominal release factor MTRFR may also play a role in elongation.
In bacteria, selenocysteinyl-tRNA requires a special elongation factor SelB () related to EF-Tu. A few homologs are also found in archaea, but the functions are unknown.
As a target
Elongation factors are targets for the toxins of some pathogens. For instance, Corynebacterium diphtheriae produces diphtheria to
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https://en.wikipedia.org/wiki/APCC
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APCC may refer to:
American Potash and Chemical Company, American chemical manufacturer
Anaphase-promoting complex (sometimes abbreviated as APC/C), an enzyme that regulates the spindle checkpoint
APCC, former Nasdaq symbol for APC by Schneider Electric, an American manufacturer
APEC Climate Center, the Climate Centre for the Asia-Pacific Economic Cooperation
Asia Pop Comic Convention, an annual comic book fan convention in Metro Manila, Philippines
Asian and Pacific Coconut Community, an intergovernmental organization of coconut producing nations
Assam Pradesh Congress Committee, a branch of the Indian National Congress political party in Assam, India
Andhra Pradesh Congress Committee, a branch of the Indian National Congress political party in Andhra Pradesh, India
Association of Police and Crime Commissioners, a group of elected officials in England and Wales
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https://en.wikipedia.org/wiki/Lubert%20Stryer
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Lubert Stryer (born March 2, 1938, in Tianjin, China) is the Emeritus Mrs. George A. Winzer Professor of Cell Biology, at Stanford University School of Medicine. His research over more than four decades has been centered on the interplay of light and life. In 2007 he received the National Medal of Science from President Bush at a ceremony at the White House for elucidating the biochemical basis of signal amplification in vision, pioneering the development of high density microarrays for genetic analysis, and authoring the standard undergraduate biochemistry textbook, Biochemistry. It is now in its ninth edition and also edited by Jeremy Berg, John L. Tymoczko and Gregory J. Gatto, Jr.
Stryer received his B.S. degree from the University of Chicago in 1957 and his M.D. degree from Harvard Medical School. He was a Helen Hay Whitney Research Fellow in the department of physics at Harvard and then at the MRC Laboratory of Molecular Biology in Cambridge, England, before joining the faculty of the department of biochemistry at Stanford in 1963. In 1969 he moved to Yale to become Professor of Molecular Biophysics and Biochemistry, and in 1976, he returned to Stanford to head a new Department of Structural Biology.
Research profile
Stryer and coworkers pioneered the use of fluorescence spectroscopy, particularly Förster resonance energy transfer (FRET), to monitor the structure and dynamics of biological macromolecules. In 1967, Stryer and Haugland showed that the efficiency of ener
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https://en.wikipedia.org/wiki/Kelvin%20equation
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The Kelvin equation describes the change in vapour pressure due to a curved liquid–vapor interface, such as the surface of a droplet. The vapor pressure at a convex curved surface is higher than that at a flat surface. The Kelvin equation is dependent upon thermodynamic principles and does not allude to special properties of materials. It is also used for determination of pore size distribution of a porous medium using adsorption porosimetry. The equation is named in honor of William Thomson, also known as Lord Kelvin.
Formulation
The original form of the Kelvin equation, published in 1871, is:
where:
= vapor pressure at a curved interface of radius
= vapor pressure at flat interface () =
= surface tension
= density of vapor
= density of liquid
, = radii of curvature along the principal sections of the curved interface.
This may be written in the following form, known as the Ostwald–Freundlich equation:
where is the actual vapour pressure,
is the saturated vapour pressure when the surface is flat,
is the liquid/vapor surface tension, is the molar volume of the liquid, is the universal gas constant, is the radius of the droplet, and is temperature.
Equilibrium vapor pressure depends on droplet size.
If the curvature is convex, is positive, then
If the curvature is concave, is negative, then
As increases, decreases towards , and the droplets grow into bulk liquid.
If the vapour is cooled, then decreases, but so does . This means increases a
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https://en.wikipedia.org/wiki/AIMACO
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AIMACO is an acronym for AIr MAterial COmpiler. It began around 1959 as the definition of a high level programming language influenced by the FLOW-MATIC language, developed by UNIVAC, and the COMTRAN (COMmercial TRANslator) programming language, developed by IBM. AIMACO, along with FLOW-MATIC and COMTRAN, were precursors to the COBOL programming language and influenced its development.
A committee chaired by a representative of AMC (the Air Material Command, predecessor to the Air Force Materiel Command) and composed of industry representatives from IBM and United States Steel, as well as members of AMC Programming Services, developed the draft AIMACO language definition. Even though the word "compiler" was part of its name, no compiler was ever written for it; although at least two were specified or designed.
The original intention of AMC was that all programming for AMC systems worldwide would be written in AIMACO and compiled on a UNIVAC in AMC headquarters at Wright-Patterson Air Force Base, Dayton, Ohio. This would be for software whether it was intended to operate on UNIVAC or IBM computers. An alternative compiler was designed by AMC Programming Services persons to compile systems on IBM computers for operation on IBM computers.
References
Computer languages
Wright-Patterson Air Force Base
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https://en.wikipedia.org/wiki/Electronic%20packaging
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Electronic packaging is the design and production of enclosures for electronic devices ranging from individual semiconductor devices up to complete systems such as a mainframe computer. Packaging of an electronic system must consider protection from mechanical damage, cooling, radio frequency noise emission and electrostatic discharge. Product safety standards may dictate particular features of a consumer product, for example, external case temperature or grounding of exposed metal parts. Prototypes and industrial equipment made in small quantities may use standardized commercially available enclosures such as card cages or prefabricated boxes. Mass-market consumer devices may have highly specialized packaging to increase consumer appeal. Electronic packaging is a major discipline within the field of mechanical engineering.
Design
Electronic packaging can be organized by levels:
Level 0 - "Chip", protecting a bare semiconductor die from contamination and damage.
Level 1 - Component, such as semiconductor package design and the packaging of other discrete components.
Level 2 - Etched wiring board (printed circuit board).
Level 3 - Assembly, one or more wiring boards and associated components.
Level 4 - Module, assemblies integrated in an overall enclosure.
Level 5 - System, a set of modules combined for some purpose.
The same electronic system may be packaged as a portable device or adapted for fixed mounting in an instrument rack or permanent installation. Packaging
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https://en.wikipedia.org/wiki/Diploglena
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Diploglena is a genus of African araneomorph spiders in the family Caponiidae, first described by William Frederick Purcell in 1904.
Species
it contains six species:
Diploglena arida Haddad, 2015 – South Africa
Diploglena capensis Purcell, 1904 (type) – South Africa
Diploglena dippenaarae Haddad, 2015 – South Africa
Diploglena karooica Haddad, 2015 – Namibia, South Africa
Diploglena major Lawrence, 1928 – Namibia, Botswana, South Africa
Diploglena proxila Haddad, 2015 – South Africa
References
Araneomorphae genera
Caponiidae
Spiders of Africa
Taxa named by William Frederick Purcell
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https://en.wikipedia.org/wiki/Beta%20hairpin
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The beta hairpin (sometimes also called beta-ribbon or beta-beta unit) is a simple protein structural motif involving two beta strands that look like a hairpin. The motif consists of two strands that are adjacent in primary structure, oriented in an antiparallel direction (the N-terminus of one sheet is adjacent to the C-terminus of the next), and linked by a short loop of two to five amino acids. Beta hairpins can occur in isolation or as part of a series of hydrogen bonded strands that collectively comprise a beta sheet.
Researchers such as Francisco Blanco et al. have used protein NMR to show that beta-hairpins can be formed from isolated short peptides in aqueous solution, suggesting that hairpins could form nucleation sites for protein folding.
Classification
Beta hairpins were originally categorized solely by the number of amino acid residues in their loop sequences, such that they were named one-residue, two-residue, etc. This system, however, is somewhat ambiguous as it does not take into account whether the residues that signal the end of the hairpin are singly or doubly hydrogen bonded to one another. An improved means of classification has since been proposed by Milner-White and Poet. Beta hairpins are broken into four distinct classes as depicted in the publication's Figure 1. Each class begins with the smallest possible number of loop residues and progressively increases the loop size by removing hydrogen bonds in the beta sheet. The primary hairpin of class 1
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https://en.wikipedia.org/wiki/Bais%20%28Rajput%20clan%29
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The Bais () is a Rajput clan from India.
History
Their wealth caused Donald Butter, a visiting doctor who wrote Outlines of the Topography and Statistics of the Southern Districts of Oudh, and of the Cantonment of Sultanpur-Oudh, to describe the Bais Rajput in the 1830s as the "best dressed and housed people of the southern Oudh".
The Bais Rajputs were known for well-building.
See also
Baiswara
Rajput clans
References
Rajput clans of Uttar Pradesh
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https://en.wikipedia.org/wiki/Transferable%20belief%20model
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The transferable belief model (TBM) is an elaboration on the Dempster–Shafer theory (DST), which is a mathematical model used to evaluate the probability that a given proposition is true from other propositions that are assigned probabilities. It was developed by Philippe Smets who proposed his approach as a response to Zadeh’s example against Dempster's rule of combination. In contrast to the original DST the TBM propagates the open-world assumption that relaxes the assumption that all possible outcomes are known. Under the open world assumption Dempster's rule of combination is adapted such that there is no normalization. The underlying idea is that the probability mass pertaining to the empty set is taken to indicate an unexpected outcome, e.g. the belief in a hypothesis outside the frame of discernment. This adaptation violates the probabilistic character of the original DST and also Bayesian inference. Therefore, the authors substituted notation such as probability masses and probability update with terms such as degrees of belief and transfer giving rise to the name of the method: The transferable belief model.
Zadeh’s example in TBM context
Lofti Zadeh describes an information fusion problem. A patient has an illness that can be caused by three different factors A, B or C. Doctor 1 says that the patient's illness is very likely to be caused by A (very likely, meaning probability p = 0.95), but B is also possible but not likely (p = 0.05). Doctor 2 says that the cause
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https://en.wikipedia.org/wiki/Sommerfeld%20radiation%20condition
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In applied mathematics, and theoretical physics the Sommerfeld radiation condition is a concept from theory of differential equations and scattering theory used for choosing a particular solution to the Helmholtz equation. It was introduced by Arnold Sommerfeld in 1912
and is closely related to the limiting absorption principle (1905) and the limiting amplitude principle (1948).
The boundary condition established by the principle essentially chooses a solution of some wave equations which only radiates outwards from known sources. It, instead, of allowing arbitrary inbound waves from the infinity propagating in instead detracts from them.
The theorem most underpinned by the condition only holds true in three spatial dimensions. In two it breaks down because wave motion doesn't retain its power as one over radius squared. On the other hand, in spatial dimensions four and above, power in wave motion falls off much faster in distance.
Formulation
Arnold Sommerfeld defined the condition of radiation for a scalar field satisfying the Helmholtz equation as
"the sources must be sources, not sinks of energy. The energy which is radiated from the sources must scatter to infinity; no energy may be radiated from infinity into ... the field."
Mathematically, consider the inhomogeneous Helmholtz equation
where is the dimension of the space, is a given function with compact support representing a bounded source of energy, and is a constant, called the wavenumber. A solution to
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https://en.wikipedia.org/wiki/Krause
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Krause (German for ruffle) is a common German surname.
Geographical distribution
As of 2014, 64.9% of all known bearers of the surname Krause were residents of Germany (frequency 1:531), 20.6% of the United States (1:7,541), 3.5% of Brazil (1:24,831), 2.4% of South Africa (1:9,550), 2.1% of Poland (1:7,891), 1.4% of Canada (1:11,446) and 1.2% of Australia (1:8,488).
In Germany, the frequency of the surname was higher than national average (1:531) in the following states:
1. Brandenburg (1:204)
2. Saxony-Anhalt (1:240)
3. Mecklenburg-Vorpommern (1:250)
4. Berlin (1:279)
5. Saxony (1:305)
6. Schleswig-Holstein (1:345)
7. Thuringia (1:388)
8. Lower Saxony (1:448)
9. Bremen (1:464)
10. Hamburg (1:506)
People
Alan Krause, a former Australian rules footballer who played with Melbourne
Albert A. Krause, (1841–1913), US Civil War Veteran, City Engineer of Buffalo NY, brother of Aurel Krause, great grandfather of Tory Bruno
Allison Krause (1951–1970), a student at Kent State University, Ohio who was shot and killed by the Ohio National Guard
Arnulf Krause (born 1955), a German philologist
Asuman Krause, a German-born former model and singer of mixed Turkish and German descent
Aurel Krause, (1848–1908), a German geographer known today for his early ethnography of the Tlingit Indians of southeast Alaska, brother of Albert Krause and great grand uncle of Tory Bruno
Axel Krause (born 1958), a German painter and graphic artist
Barbara Krause (born 1959), a former freestyle swi
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https://en.wikipedia.org/wiki/Computer-assisted%20reviewing
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Computer-assisted reviewing (CAR) tools are pieces of software based on text-comparison and analysis algorithms. These tools focus on the differences between two documents, taking into account each document's typeface through an intelligent analysis.
Detecting differences
The intelligent analysis used by CAR tools detect the differences do not have the same value depending on their type and/or the document field/subject. For example, a difference on a number is not the same if this number is a date, a price, a page number, a figure number, a part of an address, a footnote call, a list item number, a title number, etc.
a title number or a list item number difference can be of no interest if these numbers will be re-calculated afterward before printing or publishing by a text processing tool,
a small number difference like "1" to "one" or "1" to "1st" is often of secondary interest, depending on the subject and the field of the document
while some other number differences can be very damageable to the document.
These tools are interesting in various kind of applications:
comparison between a document and an updated/modified version of it. The main goal is then to highlight the modifications made by a third person or a text processing software.
comparison between a document edited two file formats: Word, TXT, PDF, HTML, XML. The main goal is to highlight differences implied by the format modification or the conversion/re-formatter software. Often, simple char encoding con
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https://en.wikipedia.org/wiki/HEC-RAS
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HEC-RAS is simulation software used in computational fluid dynamics – specifically, to model the hydraulics of water flow through natural rivers and other channels. Prior to the 2016 update to Version 5.0, the program was one-dimensional, meaning that there is no direct modeling of the hydraulic effect of cross section shape changes, bends, and other two- and three-dimensional aspects of flow. The release of Version 5.0 introduced two-dimensional modeling of flow as well as sediment transfer modeling capabilities. The program was developed by the United States Army Corps of Engineers in order to manage the rivers, harbors, and other public works under their jurisdiction; it has found wide acceptance by many others since its public release in 1995.
The Hydrologic Engineering Center (HEC) in Davis, California, developed the River Analysis System (RAS) to aid hydraulic engineers in channel flow analysis and floodplain determination. It includes numerous data entry capabilities, hydraulic analysis components, data storage and management capabilities, and graphing and reporting capabilities.
Functionality
The basic computational procedure of HEC-RAS for steady flow is based on the solution of the one-dimensional energy equation. Energy losses are evaluated by friction and contraction / expansion. The momentum equation may be used in situations where the water surface profile is rapidly varied. These situations include hydraulic jumps, hydraulics of bridges, and evaluating pro
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https://en.wikipedia.org/wiki/Ravindran%20Kannan
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Ravindran Kannan (; born 12 March 1953, Madras) is a Principal Researcher at Microsoft Research India, where he leads the algorithms research group. He is also the first adjunct faculty of Computer Science and Automation Department of Indian Institute of Science.
Before joining Microsoft, he was the William K. Lanman Jr. Professor of Computer Science and Professor of Applied Mathematics at Yale University. He has also taught at MIT, CMU and IISc. The ACM Special Interest Group on Algorithms and Computation Theory (SIGACT) presented its 2011 Knuth Prize to Ravi Kannan for developing influential algorithmic techniques aimed at solving long-standing computational problems. He also served on the Mathematical Sciences jury for the Infosys Prize in 2012 and 2013.
Ravi Kannan did his B.Tech at IIT, Bombay. He received his PhD in 1980 at Cornell University under Leslie Earl Trotter, Jr. His research interests include Algorithms, Theoretical Computer Science and Discrete Mathematics as well as Optimization. His work has mainly focused on efficient algorithms for problems of a mathematical (often geometric) flavor that arise in Computer Science. He has worked on algorithms for integer programming and the geometry of numbers, random walks in n-space, randomized algorithms for linear algebra and learning algorithms for convex sets.
Key contributions
Among his many contributions, two are
Polynomial-time algorithm for approximating the volume of convex bodies
Algorithmic version for
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https://en.wikipedia.org/wiki/2QN
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2QN is a radio station based in Deniliquin, New South Wales, Australia. It broadcasts on the medium wave radio band, at a frequency of 1521 kHz.
2QN combines a 'Hits & Memories' music format with talk radio and news.
The station's breakfast former announcer, Paul Dix, was the longest serving breakfast announcer in Australia at the one station. He had over 50 years experience in radio and has been in Deniliquin since 1961. Paul died in 2013.
The studios were destroyed by fire in 1939.
In the mid-1940s the station was under threat of being relocated to Wangaratta, which caused protests in Deniliquin.
In 1952, the station increased its operating power from 200W to 2000W, along with a change in frequency to .
The station is located in George Street, Deniliquin, in a purpose-built building.
Main programs
Morning Rush with Sean Cullen
Mornings with Neil Mitchell
Country Today – Rural News and interviews with Libby Price
Sportsday
Nights with Denis Walter
References
External links
2QN website
Radio stations in New South Wales
Radio stations established in 1935
Classic hits radio stations in Australia
Ace Radio
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https://en.wikipedia.org/wiki/Cell%20physiology
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Cell physiology is the biological study of the activities that take place in a cell to keep it alive. The term physiology refers to normal functions in a living organism. Animal cells, plant cells and microorganism cells show similarities in their functions even though they vary in structure.
General characteristics
There are two types of cells: prokaryotes and eukaryotes.
Prokaryotes were the first of the two to develop and do not have a self-contained nucleus. Their mechanisms are simpler than later-evolved eukaryotes, which contain a nucleus that envelops the cell's DNA and some organelles.
Prokaryotes
Prokaryotes have DNA located in an area called the nucleoid, which is not separated from other parts of the cell by a membrane. There are two domains of prokaryotes: bacteria and archaea. Prokaryotes have fewer organelles than eukaryotes. Both have plasma membranes and ribosomes (structures that synthesize proteins and float free in cytoplasm). Two unique characteristics of prokaryotes are fimbriae (finger-like projections on the surface of a cell) and flagella (threadlike structures that aid movement).
Eukaryotes
Eukaryotes have a nucleus where DNA is contained. They are usually larger than prokaryotes and contain many more organelles. The nucleus, the feature of a eukaryote that distinguishes it from a prokaryote, contains a nuclear envelope, nucleolus and chromatin. In cytoplasm, endoplasmic reticulum (ER) synthesizes membranes and performs other metabolic activit
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https://en.wikipedia.org/wiki/Functional%20training
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Functional training is a classification of exercise which involves training the body for the activities performed in daily life.
Origins
Functional training has its origins in rehabilitation. Physical and occupational therapists and chiropractors often use this approach to retrain patients with movement disorders. Interventions are designed to incorporate task and context specific practice in areas meaningful to each patient, with an overall goal of functional independence. For example, exercises that mimic what patients did at home or work may be included in treatment in order to help them return to their lives or jobs after an injury or surgery. Thus if a patient's job required repeatedly heavy lifting, rehabilitation would be targeted towards heavy lifting, if the patient were a parent of young children, it would be targeted towards moderate lifting and endurance, and if the patient were a marathon runner, training would be targeted towards re-building endurance. However, treatments are designed after careful consideration of the patient's condition, what he or she would like to achieve, and ensuring goals of treatment are realistic and achievable.
Functional training attempts to adapt or develop exercises which allow individuals to perform the activities of daily life more easily and without injuries. While completing a functional training activity, the body consumes more oxygen, 1 liter for about every 5 calories of energy burned when more muscles are used.
In the co
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https://en.wikipedia.org/wiki/Signal%20patch
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A protein signal patch contains information to send a given protein to the indicated location in the cell. It is made up of amino acid residues that are distant to one another in the primary sequence, but come close to each other in the tertiary structure of the folded protein (see red patch in the diagram). Signal patches, unlike some signal sequences, are not cleaved from the mature protein after sorting. They are very difficult to predict. Nuclear localization signals are often signal patches although signal sequences also exist. They are found on proteins destined for the nucleus and enable their selective transport from the cytosol into the nucleus through the nuclear pore complexes.
See also
protein targeting
signal peptide
Protein targeting
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https://en.wikipedia.org/wiki/Planar%20Doppler%20velocimetry
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Planar Doppler Velocimetry (PDV), also referred to as Doppler Global Velocimetry (DGV), determines flow velocity across a plane by measuring the Doppler shift in frequency of light scattered by particles contained in the flow. The Doppler shift, Δfd, is related to the fluid velocity.
The relatively small frequency shift (order 1 GHz) is discriminated using an atomic or molecular vapor filter. This approach is conceptually similar to what is now known as Filtered Rayleigh Scattering (Miles and Lempert, 1990).
Equipment
Up to now, a typical one-component PDV instrument utilizes a pulsed injection-seeded Nd:YAG laser, one or two scientific grade CCD cameras and a molecular iodine filter. The laser is used to illuminate a plane of the flow with narrow spectral linewidth light. The Doppler shifted scattered light is then split into two paths using a beamsplitter and imaged onto the camera(s). In this manner the absolute absorption of scattered light, as it passes through an iodine cell placed in one of the beam paths, is measured at every spatial location within the object plane. For scattering by relatively large (i.e. Mie scattering) particles, this absorption is a function of particle velocity alone. Accurate calibration and image mapping algorithms have been developed with the result that velocity accuracies of ~1–2 m/s are possible. More details concerning the history of PDV, the art of its application and recent advances can be found in comprehensive review article
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https://en.wikipedia.org/wiki/Mahuva%2C%20Surat
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Mahuwa is a town in Surat district in the Indian state of Gujarat.
History
Shri Vighn-har Parshv Nath (Atishaya Kshetra) Digamber Jain Mandir is situated at the bank of Poorna river, opposite to Pavagarh, Taranga, Gajpantha, Girnar etc. kshetras situated at hills in Gujarat.
In ancient times, this temple was famous as Shri 1008 Bhagvan Chandra-Prabhu Digamber Jain Mandir and this village was called Madhupuri. Script carved on wooden pillars of temple shows that this kshetra is more than 1000 years old. This temple was reconstructed in V. S. 1625 & 1827. building of temple shows that 1000 years ago, there lived a huge population of Jains in this area.
Appearance & Miracles of Bhagvan Vighn-Har Parshv Nath Shri Vighn-Har Parshv Nath's idol was found in a farm of a farmer in village Sultanabad, District Pashchim Khan Desh (Maharashtra). For some time the idol was worshipped in farm, later on to shift the idol to a safe and suitable place, a group traveling was organized with idol placed in a chariot. On the rout of traveling, at many places efforts were made to bring idol out of chariot, but all failed. Neither the chariot was stopped nor the idol could be brought down the chariot. At last, the chariot stopped before Bhagvan Chandra Prabhu Digamber Jain Mandir of Mahua and hear the idol was easily brought down of chariot. Then a Panch Kalyanak Pratishtha Mahotsava was organized, and thus reverenced idol was established in the central room of temple. Bhagvan Chandra Prabhu's i
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https://en.wikipedia.org/wiki/Pentafluoropropane
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1,1,1,3,3-Pentafluoropropane (HFC-245fa) is a hydrofluorocarbon is a colorless gas used primarily for closed-cell spray foam insulation. HFC-245fa is also known as pentafluoropropane and by its chemical name 1,1,1,3,3-pentafluoropropane.
Environmental Effects
Unlike CFC and HCFC blowing agents formerly used for this purpose, it has no ozone depletion potential and is nearly non-toxic. Although it is intended to remain trapped within the foam insulation, it is practically non-biodegradable with a lifetime of 7.2 years when it eventually does escape into the atmosphere. It does have a high global warming potential of 950 (950 times the global warming effect of ). Honeywell refers to this as "acceptable" in their literature, but they don't include the actual number.
Economics
One of the disadvantages of R-245fa is its cost. In 2000, R-141b cost one US dollar per pound, whereas R-245fa cost $2.50 to $4.00 per pound. As of 2007, and prior to Sinochem's production it was already a high volume production chemical, with over 1 million pounds produced annually.
Manufacturing History
Pentafluoropropane is produced by Honeywell and in Asia by Sinochem. Honeywell markets HFC-245fa under the Enovate and Genetron 245fa brand names. AlliedSignal, who adopted the Honeywell name after acquiring it, decided in 1999 to provide a non ozone depleting blowing agent as an alternative for dichlorofluoroethane (HCFC-141b) and trichlorofluoromethane (CFC-11). Competitors Atofina and General
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https://en.wikipedia.org/wiki/Pobiti%20Kamani
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Pobiti Kamani (, "planted stones"), tubular concretions formed around "rising methane-bearing fluid plumes", is a desert-like rock phenomenon located on the north west Varna Province border in Bulgaria.
The stone pillars were first described by Russian archaeologist and historian Victor Teplyakov in 1829. In order to be preserved, Pobiti Kamani was designated a natural landmark in the late 1930s.
There are a number of theories regarding the phenomenon's origin. The pioneering hypothesis can be divided roughly into two groups: suggesting an organic or abiotic origin. According to the former, the formations are the result of coral activity (but detail investigation shows no coral), while the latter explains the phenomenon with the prismatic weathering and desertification of the rocks, the formation of sand and limestone concretions, or lower Eocene bubbling reefs.
Based on a petrographic and stable isotope geochemical study and field observations, evidence exists that these structures represent an exceptional record of paleo-hydrocarbon seep system (low magnesium calcite cements are strongly depleted in heavy carbon isotope 13C). The pathways of fluid circulation are recorded as columns set in sands, which columns after recent sand removal produced a desert-like landscape. The dynamic reconstruction of the origin of these structures, the processes of fluid migration and microbial mediation of hydrocarbon oxidation leading to carbonate precipitation have been studied by De B
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https://en.wikipedia.org/wiki/Nucleotidase
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A nucleotidase is a hydrolytic enzyme that catalyzes the hydrolysis of a nucleotide into a nucleoside and a phosphate.
A nucleotide + H2O = a nucleoside + phosphate
For example, it converts adenosine monophosphate to adenosine, and guanosine monophosphate to guanosine.
Nucleotidases have an important function in digestion in that they break down consumed nucleic acids.
They can be divided into two categories, based upon the end that is hydrolyzed:
: 5'-nucleotidase - NT5C, NT5C1A, NT5C1B, NT5C2, NT5C3
: 3'-nucleotidase - NT3
5'-Nucleotidases cleave off the phosphate from the 5' end of the sugar moiety. They can be classified into various kinds depending on their substrate preferences and subcellular localization. Membrane-bound 5'-nucleotidases display specificity toward adenosine monophosphates and are involved predominantly in the salvage of preformed nucleotides and in signal transduction cascades involving purinergic receptors. Soluble 5'-nucleotidases are all known to belong to the haloacid dehalogenase superfamily of enzymes, which are two domain proteins characterised by a modified Rossman fold as the core and variable cap or hood. The soluble forms are further subclassified based on the criterion mentioned above. mdN and cdN are mitochondrial and cytosolic 5'-3'-pyrimidine nucleotidases. cN-I is a cytosolic nucleotidase(cN) characterized by its affinity toward AMP as its substrate. cN-II is identified by its affinity toward either IMP or GMP or both. cN-III is
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https://en.wikipedia.org/wiki/List%20of%20scientific%20priority%20disputes
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This is a list of priority disputes in science and science-related fields (such as mathematics).
Mathematics
Rule for solving cubic equations: Niccolò Tartaglia, Gerolamo Cardano
Leibniz–Newton calculus controversy: Isaac Newton, Gottfried Leibniz
Physics
Mechanical equivalent of heat: James Prescott Joule, Julius von Mayer
Radio waves: James Clerk Maxwell, Oliver Lodge, Heinrich Hertz, David Edward Hughes
Special relativity priority dispute: Albert Einstein, Henri Poincaré, Hendrik Lorentz
General relativity priority dispute: Albert Einstein, David Hilbert
Chandrasekhar limit: Subrahmanyan Chandrasekhar, Edmund Clifton Stoner, Wilhelm Anderson
Eightfold Way: Murray Gell-Mann, Yuval Ne'eman
Accelerating expansion of the universe: High-Z Supernova Search Team, Supernova Cosmology Project.
Astronomy
Controversy over the discovery of Haumea: José Luis Ortiz Moreno et al., Michael E. Brown et al.
Sunspots: Galileo, Christoph Scheiner
Geoheliocentric system: Tycho Brahe, Nicolaus Raimarus Ursus
Galilean moons: Galileo, Simon Marius
Prediction of Neptune: Urbain Le Verrier, John Couch Adams
Chemistry
Oxygen: Joseph Priestley, Carl Wilhelm Scheele, Antoine Laurent Lavoisier
Periodic table: Dmitri Mendeleev, Lothar Meyer
Biology and medicine
Evolution: Charles Darwin, Alfred Russel Wallace, Patrick Matthew
Opiate receptor: Candace Pert, Solomon H. Snyder
DNA structure: Francis Crick, James D. Watson, Rosalind Franklin, Erwin Chargaff, Oswald Avery
Lymphatic system: Olo
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https://en.wikipedia.org/wiki/Neutral%20buoyancy
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Neutral buoyancy occurs when an object's average density is equal to the density of the fluid in which it is immersed, resulting in the buoyant force balancing the force of gravity that would otherwise cause the object to sink (if the body's density is greater than the density of the fluid in which it is immersed) or rise (if it is less). An object that has neutral buoyancy will neither sink nor rise.
In scuba diving, the ability to maintain neutral buoyancy through controlled breathing, accurate weighting, and management of the buoyancy compensator is an important skill. A scuba diver maintains neutral buoyancy by continuous correction, usually by controlled breathing, as neutral buoyancy is an unstable condition for a compressible object in a liquid.
History
The mathematician Archimedes discovered much of how buoyancy works more than 2000 years ago. In his research, Archimedes discovered that an object is buoyed up by a force equal to the weight of the water displaced by the object. In other words, an inflatable boat that displaces 100 pounds (45 kilograms) of water is supported by the same amount of force. An object that floats in a fluid is known as being positively buoyant. An object that sinks to the bottom is negatively buoyant, while an object that remains in balance at the same level in the fluid is neutrally buoyant. Ways to adjust buoyancy were developed to produce equipment such as the inflatable life jacket, which is filled with gas and helps to reduce a person
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https://en.wikipedia.org/wiki/Double%20counting%20%28fallacy%29
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Double counting is a fallacy in reasoning.
An example of double counting is shown starting with the question: What is the probability of seeing at least one 5 when throwing a pair of dice? An erroneous argument goes as follows: The first die shows a 5 with probability 1/6, and the second die shows a 5 with probability 1/6; therefore, the probability of seeing a 5 on at least one of the dice is 1/6 + 1/6 = 1/3 = 12/36. However, the correct answer is 11/36, because the erroneous argument has double-counted the event where both dice show 5s.
Double counting can be generalized as the fallacy in which, when counting events or occurrences in probability or in other areas, a solution counts events two or more times, resulting in an erroneous number of events or occurrences which is higher than the true result. This results in the calculated sum of probabilities for all possible outcomes to be higher than 100%, which is impossible.
In mathematical terms, the previous example calculated the probability of P(A or B) as P(A)+P(B). However, by the inclusion-exclusion principle, P(A or B) = P(A) + P(B) - P(A and B), one compensates for double counting by subtracting those objects which were double counted.
Another example is made in the joke where a man explains to his boss why he has to be an hour late to work every day:
8760 (365*24) hours compose one year.
He needs 8 hours sleep daily (365*8) 2920 hours leaving 5840 hours.
He uses an hour and 30 minutes per meal, (1.5*365) or 54
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https://en.wikipedia.org/wiki/Viral%20culture
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Viral culture is a laboratory technique in which samples of a virus are placed to different cell lines which the virus being tested for its ability to infect. If the cells show changes, known as cytopathic effects, then the culture is positive.
Traditional viral culture has been generally superseded by shell vial culture, in which the sample is centrifuged onto a single layer of cells and viral growth is measured by antigen detection methods. This greatly reduces the time to detection for slow growing viruses such as cytomegalovirus, for which the method was developed. In addition, the centrifugation step in shell vial culture enhances the sensitivity of this method because after centrifugation, the viral particles of the sample are in close proximity to the cells.
Human and monkey cells are used in both traditional viral culture and shell vial culture.
Human virus types that can be identified by viral culture include adenovirus, cytomegalovirus, enteroviruses, herpes simplex virus, influenza virus, parainfluenza virus, rhinovirus, respiratory syncytial virus, varicella zoster virus, measles and mumps. For these, the final identification method is generally by immunofluorescence, with exception of cytomegalovirus and rhinovirus, whose identification in a viral culture are determined by cytopathic effects.
Preliminary research (i.e. not yet peer reviewed at the time of writing, 29 September 2020) exploring the potential suitability of viral culture testing of SARS-CoV-2 ha
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https://en.wikipedia.org/wiki/Don%20Berry%20%28statistician%29
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Donald Arthur Berry (born May 26, 1940) is an American statistician and a practitioner and proponent of Bayesian statistics in medical science. He was the chairman of the Department of Biostatistics and Applied Mathematics at the University of Texas M. D. Anderson Cancer Center from 1999-2010, where he played a role in the use of Bayesian methods to develop innovative, adaptive clinical trials. He is best known for the development of statistical theory relating to the design of clinical trials. He is a fellow of the American Statistical Association and the Institute of Mathematical Sciences. He founded Berry Consultants, a statistical consulting group, with Scott Berry in 2000.
Biography
Berry was born in Southbridge, Massachusetts, in 1940, and obtained an A.B. in mathematics from Dartmouth College, before moving to Yale University where he received an M.A. and Ph.D. in statistics. Berry initially "flunked out" of his undergraduate education at Dartmouth and joined the army, being stationed in Panama, but at the request of his Dean he returned to Dartmouth to complete his undergraduate education in mathematics.
References
External links
1940 births
Living people
American statisticians
Bayesian statisticians
Yale Graduate School of Arts and Sciences alumni
University of Minnesota faculty
Duke University faculty
University of Texas faculty
Fellows of the American Statistical Association
Dartmouth College alumni
People from Southbridge, Massachusetts
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https://en.wikipedia.org/wiki/Leptoid
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A leptoid is a type of elongated food-conducting cell like phloem in the stems of some mosses, such as the family Polytrichaceae. They surround strands of water-conducting hydroids. They have some structural and developmental similarities to the sieve elements of seedless vascular plants. At maturity they have inclined end cell walls with small pores and degenerate nuclei. The conduction cells of mosses, leptoids and hydroids, appear similar to those of fossil protracheophytes. However they're not thought to represent an intermediate stage in the evolution of plant vascular tissues but to have had an independent evolutionary origin.
See also
Hydroid, a related water-transporting cell analogous the xylem of vascular plants
References
Mosses
Plant physiology
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https://en.wikipedia.org/wiki/Sialyltransferase
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Sialyltransferases are enzymes that transfer sialic acid to nascent oligosaccharide. Each sialyltransferase is specific for a particular sugar substrate. Sialyltransferases add sialic acid to the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins.
The biosynthesis of disaccharides, oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. A classification of glycosyltransferases using nucleotide diphospho-sugar, nucleotide monophospho-sugar and sugar phosphates () and related proteins into distinct sequence based families has been described. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. The same three-dimensional fold is expected to occur within each of the families. Because 3-D structures are better conserved than sequences, several of the families defined on the basis of sequence similarities may have similar 3-D structures and therefore form 'clans'.
Sialyltransferases belong to glycosyltransferase family 29 (CAZY GT_29) which comprises enzymes with a number of known activities; sialyltransferase (), beta-galactosamide alpha-2,6-sialyltransferase (), alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (), beta-galactoside alpha-2,3-sialyltransferase (), N-acetyllactosaminide
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https://en.wikipedia.org/wiki/Phi%20value%20analysis
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Phi value analysis, analysis, or -value analysis is an experimental protein engineering technique for studying the structure of the folding transition state of small protein domains that fold in a two-state manner. The structure of the folding transition state is hard to find using methods such as protein NMR or X-ray crystallography because folding transitions states are mobile and partly unstructured by definition. In -value analysis, the folding kinetics and conformational folding stability of the wild-type protein are compared with those of point mutants to find phi values. These measure the mutant residue's energetic contribution to the folding transition state, which reveals the degree of native structure around the mutated residue in the transition state, by accounting for the relative free energies of the unfolded state, the folded state, and the transition state for the wild-type and mutant proteins.
The protein's residues are mutated one by one to identify residue clusters that are well-ordered in the folded transition state. These residues' interactions can be checked by double-mutant-cycle analysis, in which the single-site mutants' effects are compared to the double mutants'. Most mutations are conservative and replace the original residue with a smaller one (cavity-creating mutations) like alanine, though tyrosine-to-phenylalanine, isoleucine-to-valine and threonine-to-serine mutants can be used too. Chymotrypsin inhibitor, SH3 domains, WW domain, individual
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