Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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DNA damage response hydrogen peroxide catabolic process hyperosmotic response response to oxidative stress | cytoplasm; cytosol | catalase activity heme binding identical protein binding iron ion binding | Escherichia coli | 3D-structure Cytoplasm Direct protein sequencing Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Reference proteome | MSQHNEKNPH | MSQHNEKNPHQHQSPLHDSSEAKPGMDSLAPEDGSHRPAAEPTPPGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKITPVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRR... | DNA damage response hydrogen peroxide catabolic process hyperosmotic response response to oxidative stress cytoplasm; cytosol catalase activity heme binding identical protein binding iron ion binding Escherichia coli 3D-structure Cytoplasm Direct protein sequencing Heme Hydrogen peroxide Iron Metal-binding Oxidoreducta... |
complement activation complement activation, classical pathway innate immune response positive regulation of apoptotic cell clearance proteolysis response to bacterium response to lipopolysaccharide response to nutrient response to thyroid hormone | classical-complement-pathway C3/C5 convertase complex; extracellular space | metal ion binding serine-type endopeptidase activity | Mus musculus | Alternative splicing Complement pathway Disulfide bond Glycoprotein Hydrolase Immunity Innate immunity Metal-binding Protease Reference proteome Repeat Secreted Serine protease Signal Sushi | MAPLLALFYL | MAPLLALFYLLQLGPGLAALFCNQNVNITGGNFTLSHGWAPGSLLIYSCPLGRYPSPAWRKCQSNGQWLTPRSSSHHTLRSSRMVKAVCKPVRCLAPSSFENGIYFPRLVSYPVGSNVSFECEQDFTLRGSPVRYCRPNGLWDGETAVCDNGASHCPNPGISVGTARTGLNFDLGDKVRYRCSSSNMVLTGSAERECQSNGVWSGSEPICRQPYSYDFPEDVASALDTSLTNLLGATNPTQNLLTKSLGRKIIIQRSGHLNLYLLLDASQSVTEKDFDIFKKSAELMVERIFSFEVNVSVAIITFASQPKTIMSILSERS... | complement activation complement activation, classical pathway innate immune response positive regulation of apoptotic cell clearance proteolysis response to bacterium response to lipopolysaccharide response to nutrient response to thyroid hormone classical-complement-pathway C3/C5 convertase complex; extracellular spa... |
pantothenate biosynthetic process spermidine biosynthetic process spermine biosynthetic process | cytoplasm; cytosol; nucleus | adenosylmethionine decarboxylase activity | Saccharomyces cerevisiae | Autocatalytic cleavage Decarboxylase Direct protein sequencing Lyase Polyamine biosynthesis Pyruvate Reference proteome S-adenosyl-L-methionine Schiff base Spermidine biosynthesis Zymogen | MTVTIKELTN | MTVTIKELTNHNYIDHELSATLDSTDAFEGPEKLLEIWFFPHKKSITTEKTLRNIGMDRWIEILKLVKCEVLSMKKTKELDAFLLSESSLFVFDHKLTMKTCGTTTTLFCLEKLFQIVEQELSWAFRTTQGGKYKPFKVFYSRRCFLFPCKQAAIHQNWADEVDYLNKFFDNGKSYSVGRNDKSNHWNLYVTETDRSTPKGKEYIEDDDETFEVLMTELDPECASKFVCGPEASTTALVEPNEDKGHNLGYQMTKNTRLDEIYVNSAQDSDLSFHHDAFAFTPCGYSSNMILAEKYYYTLHVTPEKGWSYASFESNIPVF... | pantothenate biosynthetic process spermidine biosynthetic process spermine biosynthetic process cytoplasm; cytosol; nucleus adenosylmethionine decarboxylase activity Saccharomyces cerevisiae Autocatalytic cleavage Decarboxylase Direct protein sequencing Lyase Polyamine biosynthesis Pyruvate Reference proteome S-adenos... |
cellular response to organic substance cytokine-mediated signaling pathway inflammatory response to antigenic stimulus interleukin-5-mediated signaling pathway regulation of interleukin-5 production | external side of plasma membrane; plasma membrane; receptor complex | cytokine binding cytokine receptor activity interleukin-5 receptor activity | Mus musculus | Disulfide bond Glycoprotein Membrane Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MVPVLLILVG | MVPVLLILVGALATLQADLLNHKKFLLLPPVNFTIKATGLAQVLLHWDPNPDQEQRHVDLEYHVKINAPQEDEYDTRKTESKCVTPLHEGFAASVRTILKSSHTTLASSWVSAELKAPPGSPGTSVTNLTCTTHTVVSSHTHLRPYQVSLRCTWLVGKDAPEDTQYFLYYRFGVLTEKCQEYSRDALNRNTACWFPRTFINSKGFEQLAVHINGSSKRAAIKPFDQLFSPLAIDQVNPPRNVTVEIESNSLYIQWEKPLSAFPDHCFNYELKIYNTKNGHIQKEKLIANKFISKIDDVSTYSIQVRAAVSSPCRMPGRWG... | cellular response to organic substance cytokine-mediated signaling pathway inflammatory response to antigenic stimulus interleukin-5-mediated signaling pathway regulation of interleukin-5 production external side of plasma membrane; plasma membrane; receptor complex cytokine binding cytokine receptor activity interleuk... |
chemical synaptic transmission dorsal/ventral pattern formation male meiosis cytokinesis male meiotic nuclear division mRNA splicing, via spliceosome oocyte development oogenesis positive regulation of translation regulation of compound eye photoreceptor development spermatid nucleus differentiation spermatogenesis | catalytic step 2 spliceosome; cytoplasm; cytoplasmic stress granule; cytosol; nucleus; precatalytic spliceosome; ribonucleoprotein complex; synapse | mRNA 3'-UTR binding mRNA binding poly(A) binding poly(U) RNA binding | Drosophila melanogaster | 3D-structure Reference proteome Repeat RNA-binding | MASLYVGDLP | MASLYVGDLPQDVNESGLFDKFSSAGPVLSIRVCRDVITRRSLGYAYVNFQQPADAERALDTMNFDLVRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSKGYGFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKAKLFTNVYVKNFTEDFDDEKLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDMGEGKSLYVARAQKKAERQQELKRKFEELKQKRHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMT... | chemical synaptic transmission dorsal/ventral pattern formation male meiosis cytokinesis male meiotic nuclear division mRNA splicing, via spliceosome oocyte development oogenesis positive regulation of translation regulation of compound eye photoreceptor development spermatid nucleus differentiation spermatogenesis cat... |
meiotic cell cycle positive regulation of transcription by RNA polymerase II pseudohyphal growth regulation of meiotic nuclear division regulation of sporulation resulting in formation of a cellular spore regulation of transcription by RNA polymerase II sporulation resulting in formation of a cellular spore | nucleus; transcription regulator complex | transcription factor binding | Saccharomyces cerevisiae | Activator Meiosis Nucleus Reference proteome Repressor Sporulation Transcription Transcription regulation | MQADMHGKLH | MQADMHGKLHAALEDGFFLFPFEQQQQPNIYYDTTTDQEDRPCFSFGSTISPRSWHFEKSDKIASSQLQNLVHTQPIHLINPQILFNEEFLNLENIDSQPISKETKTTKDCTMATGPERGKKSSESTRSSSLSSLFSNDESASTFHSSFNNHDNFQKSNRNGDDIDISDTIKYETNTNAQKDIKIFQENFEFNEFPYTQDFYPYTTNYTYSKPTNIHESINSKNTDSYSQYQDQFPPHTDNIHSFNNRHYSNHKSTNCNYYNNTSNNNNASDNVYEADPFIDEPQVPSYYYPLEIAFDVEKSPPPSLQKLNSKELEFLKK... | meiotic cell cycle positive regulation of transcription by RNA polymerase II pseudohyphal growth regulation of meiotic nuclear division regulation of sporulation resulting in formation of a cellular spore regulation of transcription by RNA polymerase II sporulation resulting in formation of a cellular spore nucleus; tr... |
negative regulation of transcription by RNA polymerase II positive regulation of antisense RNA transcription positive regulation of septum digestion after cytokinesis positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | cytoplasm; cytosol; nucleus | cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Saccharomyces cerevisiae | Activator DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger | MDNVVDPWYI | MDNVVDPWYINPSGFAKDTQDEEYVQHHDNVNPTIPPPDNYILNNENDDGLDNLLGMDYYNIDDLLTQELRDLDIPLVPSPKTGDGSSDKKNIDRTWNLGDENNKVSHYSKKSMSSHKRGLSGTAIFGFLGHNKTLSISSLQQSILNMSKDPQPMELINELGNHNTVKNNNDDFDHIRENDGENSYLSQVLLKQQEELRIALEKQKEVNEKLEKQLRDNQIQQEKLRKVLEEQEEVAQKLVSGATNSNSKPGSPVILKTPAMQNGRMKDNAIIVTTNSANGGYQFPPPTLISPRMSNTSINGSPSRKYHRQRYPNKSPES... | negative regulation of transcription by RNA polymerase II positive regulation of antisense RNA transcription positive regulation of septum digestion after cytokinesis positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cytoplasm; cytosol; nucleus cis-regulatory reg... |
cell-cell recognition ceramide metabolic process fucosylation macromolecule glycosylation oligosaccharide biosynthetic process oligosaccharide metabolic process positive regulation of cell-cell adhesion protein N-linked glycosylation protein O-linked glycosylation regulation of cell migration regulation of cell populat... | extracellular exosome; Golgi cisterna membrane; Golgi membrane; membrane | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity alpha-(1->3)-fucosyltransferase activity fucosyltransferase activity | Homo sapiens | Blood group antigen Glycoprotein Glycosyltransferase Golgi apparatus Lipid metabolism Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MDPLGAAKPQ | MDPLGAAKPQWPWRRCLAALLFQLLVAVCFFSYLRVSRDDATGSPRAPSGSSRQDTTPTRPTLLILLRTWPFHIPVALSRCSEMVPGTADCHITADRKVYPQADMVIVHHWDIMSNPKSRLPPSPRPQGQRWIWFNLEPPPNCQHLEALDRYFNLTMSYRSDSDIFTPYGWLEPWSGQPAHPPLNLSAKTELVAWAVSNWKPDSARVRYYQSLQAHLKVDVYGRSHKPLPKGTMMETLSRYKFYLAFENSLHPDYITEKLWRNALEAWAVPVVLGPSRSNYERFLPPDAFIHVDDFQSPKDLARYLQELDKDHARYLSYF... | cell-cell recognition ceramide metabolic process fucosylation macromolecule glycosylation oligosaccharide biosynthetic process oligosaccharide metabolic process positive regulation of cell-cell adhesion protein N-linked glycosylation protein O-linked glycosylation regulation of cell migration regulation of cell populat... |
chlorophyll biosynthetic process photosynthesis response to ethylene | chloroplast; chloroplast envelope; chloroplast outer membrane; chloroplast thylakoid; chloroplast thylakoid membrane; cytosol | mRNA binding protein domain specific binding protochlorophyllide reductase activity | Arabidopsis thaliana | 3D-structure Chlorophyll biosynthesis Chloroplast Direct protein sequencing Membrane NADP Oxidoreductase Photosynthesis Plastid Plastid outer membrane Pyrrolidone carboxylic acid Reference proteome Thylakoid Transit peptide | MALQAASLVS | MALQAASLVSSAFSVRKDAKLNASSSSFKDSSLFGASITDQIKSEHGSSSLRFKREQSLRNLAIRAQTAATSSPTVTKSVDGKKTLRKGNVVVTGASSGLGLATAKALAETGKWNVIMACRDFLKAERAAKSVGMPKDSYTVMHLDLASLDSVRQFVDNFRRTETPLDVLVCNAAVYFPTAKEPTYSAEGFELSVATNHLGHFLLARLLLDDLKKSDYPSKRLIIVGSITGNTNTLAGNVPPKANLGDLRGLAGGLNGLNSSAMIDGGDFDGAKAYKDSKVCNMLTMQEFHRRFHEETGVTFASLYPGCIASTGLFREHI... | chlorophyll biosynthetic process photosynthesis response to ethylene chloroplast; chloroplast envelope; chloroplast outer membrane; chloroplast thylakoid; chloroplast thylakoid membrane; cytosol mRNA binding protein domain specific binding protochlorophyllide reductase activity Arabidopsis thaliana 3D-structure Chlorop... |
acetaldehyde catabolic process chromatin remodeling ethanol catabolic process positive regulation of transcription by RNA polymerase II threonine catabolic process | nucleus | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific zinc ion binding | Emericella nidulans | 3D-structure Activator DNA-binding Metal-binding Nucleus Reference proteome Transcription Transcription regulation Zinc | MADTRRRQNH | MADTRRRQNHSCDPCRKGKRRCDAPENRNEANENGWVSCSNCKRWNKDCTFNWLSSQRSKAKGAAPRARTKKARTATTTSEPSTSAATIPTPESDNHDAPPVINSHDALPSWTQGLLSHPGDLFDFSHSAIPANAEDAANVQSDAPFPWDLAIPGDFSMGQQLEKPLSPLSFQAVLLPPHSPNTDDLIRELEEQTTDPDSVTDTNSVQQVAQDGSLWSDRQSPLLPENSLCMASDSTARRYARSTMTKNLMRIYHDSMENALSCWLTEHNCPYSDQISYLPPKQRAEWGPNWSNRMCIRVCRLDRVSTSLRGRALSAEED... | acetaldehyde catabolic process chromatin remodeling ethanol catabolic process positive regulation of transcription by RNA polymerase II threonine catabolic process nucleus DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific zinc ion binding Emerice... |
chloroplast organization embryo development ending in seed dormancy protein folding protein refolding protein stabilization | apoplast; chloroplast; chloroplast envelope; chloroplast stroma; cytosolic ribosome; mitochondrion; peroxisome; stromule; thylakoid | ATP binding ATP-dependent protein folding chaperone | Arabidopsis thaliana | ATP-binding Chaperone Chloroplast Nucleotide-binding Phosphoprotein Plastid Reference proteome Transit peptide | MASANALSSA | MASANALSSASVLCSSRQSKLGGGNQQQGQRVSYNKRTIRRFSVRANVKEIAFDQHSRAALQAGIDKLADCVGLTLGPRGRNVVLDEFGSPKVVNDGVTIARAIELPNAMENAGAALIREVASKTNDSAGDGTTTASILAREIIKHGLLSVTSGANPVSLKRGIDKTVQGLIEELQKKARPVKGRDDIRAVASISAGNDDLIGSMIADAIDKVGPDGVLSIESSSSFETTVEVEEGMEIDRGYISPQFVTNPEKLLAEFENARVLITDQKITAIKDIIPILEKTTQLRAPLLIIAEDVTGEALATLVVNKLRGVLNVVAV... | chloroplast organization embryo development ending in seed dormancy protein folding protein refolding protein stabilization apoplast; chloroplast; chloroplast envelope; chloroplast stroma; cytosolic ribosome; mitochondrion; peroxisome; stromule; thylakoid ATP binding ATP-dependent protein folding chaperone Arabidopsis ... |
cell death chaperone cofactor-dependent protein refolding protein refolding response to cold systemic acquired resistance | apoplast; chloroplast; chloroplast envelope; chloroplast stroma; cytosolic ribosome; nucleus; stromule | ATP binding ATP-dependent protein folding chaperone mRNA binding protein domain specific binding | Arabidopsis thaliana | ATP-binding Chaperone Chloroplast Direct protein sequencing Nucleotide-binding Phosphoprotein Plastid Reference proteome Transit peptide | MASTFTATSS | MASTFTATSSIGSMVAPNGHKSDKKLISKLSSSSFGRRQSVCPRPRRSSSAIVCAAKELHFNKDGTTIRRLQAGVNKLADLVGVTLGPKGRNVVLESKYGSPRIVNDGVTVAREVELEDPVENIGAKLVRQAAAKTNDLAGDGTTTSVVLAQGFIAEGVKVVAAGANPVLITRGIEKTAKALVTELKKMSKEVEDSELADVAAVSAGNNDEIGNMIAEAMSKVGRKGVVTLEEGKSAENNLYVVEGMQFDRGYISPYFVTDSEKMSVEFDNCKLLLVDKKITNARDLVGVLEDAIRGGYPILIIAEDIEQEALATLVVNK... | cell death chaperone cofactor-dependent protein refolding protein refolding response to cold systemic acquired resistance apoplast; chloroplast; chloroplast envelope; chloroplast stroma; cytosolic ribosome; nucleus; stromule ATP binding ATP-dependent protein folding chaperone mRNA binding protein domain specific bindin... |
proteasomal protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process | nucleus; proteasome complex; proteasome core complex, alpha-subunit complex; proteasome storage granule | mRNA binding | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Direct protein sequencing Nucleus Proteasome Reference proteome | MTSIGTGYDL | MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQKEINGDDDEDEDDSDNVMSSDDENAPVATNANATTDQEGDIHLE | proteasomal protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process nucleus; proteasome complex; proteasome core complex, alpha-subunit complex; proteasome storage granule mRNA binding Saccharomyces cerevisiae 3D-structure ... |
neuropeptide signaling pathway | extracellular region | hormone activity | Loxodonta africana | Acetylation Amidation Cleavage on pair of basic residues Direct protein sequencing Endorphin Hormone Phosphoprotein Reference proteome Secreted | SYSMEHFRWG | SYSMEHFRWGKPVGKKRRPVKVYPNGAEGESAEAFPLEFXXELARERPEPARGPEGPDEGAATQADLDNGLVAEVEATSAEKKDEGPYKMEHFRWGSPAKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAYKKGH | neuropeptide signaling pathway extracellular region hormone activity Loxodonta africana Acetylation Amidation Cleavage on pair of basic residues Direct protein sequencing Endorphin Hormone Phosphoprotein Reference proteome Secreted SYSMEHFRWG SYSMEHFRWGKPVGKKRRPVKVYPNGAEGESAEAFPLEFXXELARERPEPARGPEGPDEGAATQADLDNGLVAEVEA... |
cellular detoxification of nitrogen compound establishment of blood-nerve barrier glutathione metabolic process nitrobenzene metabolic process response to estrogen xenobiotic catabolic process | cytoplasm; cytosol; extracellular exosome; intercellular bridge; nucleus; sperm fibrous sheath | enzyme binding glutathione binding glutathione transferase activity identical protein binding protein homodimerization activity | Homo sapiens | 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Reference proteome Transferase Ubl conjugation | MSCESSMVLG | MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC | cellular detoxification of nitrogen compound establishment of blood-nerve barrier glutathione metabolic process nitrobenzene metabolic process response to estrogen xenobiotic catabolic process cytoplasm; cytosol; extracellular exosome; intercellular bridge; nucleus; sperm fibrous sheath enzyme binding glutathione bindi... |
cell cycle cell division chemotropism maintenance of protein location in nucleus mitotic cell cycle G1 arrest in response to pheromone regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion | Cdc24p-Far1p-Gbetagamma complex; cell cortex; cytoplasm; mating projection tip; nucleus | cyclin-dependent protein serine/threonine kinase inhibitor activity metal ion binding | Saccharomyces cerevisiae | Cell cycle Cell division Metal-binding Phosphoprotein Protein kinase inhibitor Reference proteome Zinc Zinc-finger | MKTPTRVSFE | MKTPTRVSFEKKIHTPPSGDRDAERSPPKKFLRGLSGKVFRKTPEFKKQQMPTFGYIEESQFTPNLGLMMSKRGNIPKPLNLSKPISPPPSLKKTAGSVASGFSKTGQLSALQSPVNITSSNKYNIKATNLTTSLLRESISDSTTMCDTLSDINLTVMDEDYRIDGDSYYEEDSPTFMISLERNIKKCNSQFSPKRYIGEKCLICEESISSTFTGEKVVESTCSHTSHYNCYLMLFETLYFQGKFPECKICGEVSKPKDKDIVPEMVSKLLTGAGAHDDGPSSNMQQQWIDLKTARSFTGEFPQFTPQEQLIRTADISCD... | cell cycle cell division chemotropism maintenance of protein location in nucleus mitotic cell cycle G1 arrest in response to pheromone regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion Cdc24p-Far1p-Gbetagamma complex; cell cortex; cytoplasm; mating projection tip; nucleu... |
tRNA 3'-terminal CCA addition | mitochondrial matrix; mitochondrion; nucleus | ATP binding ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity CCA tRNA nucleotidyltransferase activity CTP:tRNA cytidylyltransferase activity RNA binding | Saccharomyces cerevisiae | Alternative initiation ATP-binding Cytoplasm Direct protein sequencing Mitochondrion Nucleotide-binding Nucleotidyltransferase Nucleus Reference proteome RNA-binding Transferase Transit peptide | MLRSTISLLM | MLRSTISLLMNSAAQKTMTNSNFVLNAPKITLTKVEQNICNLLNDYTDLYNQKYHNKPEPLTLRITGGWVRDKLLGQGSHDLDIAINVMSGEQFATGLNEYLQQHYAKYGAKPHNIHKIDKNPEKSKHLETATTKLFGVEVDFVNLRSEKYTELSRIPKVCFGTPEEDALRRDATLNALFYNIHKGEVEDFTKRGLQDLKDGVLRTPLPAKQTFLDDPLRVLRLIRFASRFNFTIDPEVMAEMGDPQINVAFNSKISRERVGVEMEKILVGPTPLLALQLIQRAHLENVIFFWHNDSSVVKFNEENCQDMDKINHVYNDN... | tRNA 3'-terminal CCA addition mitochondrial matrix; mitochondrion; nucleus ATP binding ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity CCA tRNA nucleotidyltransferase activity CTP:tRNA cytidylyltransferase activity RNA binding Saccharomyces cerevisiae Alternative initiation ATP-binding Cytoplasm Direct prot... |
circadian rhythm response to cadmium ion response to copper ion response to light intensity response to ozone | chloroplast; chloroplast envelope; chloroplast membrane; chloroplast stroma; cytoplasm; cytosol; mitochondrion; plasma membrane; thylakoid | copper ion binding protein domain specific binding superoxide dismutase activity | Arabidopsis thaliana | Acetylation Alternative splicing Cell membrane Chloroplast Iron Membrane Metal-binding Oxidoreductase Plastid Reference proteome Transit peptide | MAASSAVTAN | MAASSAVTANYVLKPPPFALDALEPHMSKQTLEFHWGKHHRAYVDNLKKQVLGTELEGKPLEHIIHSTYNNGDLLPAFNNAAQAWNHEFFWESMKPGGGGKPSGELLALLERDFTSYEKFYEEFNAAAATQFGAGWAWLAYSNEKLKVVKTPNAVNPLVLGSFPLLTIDVWEHAYYLDFQNRRPDYIKTFMTNLVSWEAVSARLEAAKAASA | circadian rhythm response to cadmium ion response to copper ion response to light intensity response to ozone chloroplast; chloroplast envelope; chloroplast membrane; chloroplast stroma; cytoplasm; cytosol; mitochondrion; plasma membrane; thylakoid copper ion binding protein domain specific binding superoxide dismutase... |
action potential adenylate cyclase-modulating G protein-coupled receptor signaling pathway cellular response to pH cranial skeletal system development developmental pigmentation endothelin receptor signaling pathway G protein-coupled receptor signaling pathway heart development ion channel modulating, G protein-coupled... | cytoplasm; heterotrimeric G-protein complex; plasma membrane; synapse | alkylglycerophosphoethanolamine phosphodiesterase activity enzyme regulator activity G protein activity G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding protein-containing complex binding | Mus musculus | Cell membrane Cytoplasm Direct protein sequencing GTP-binding Lipoprotein Magnesium Membrane Metal-binding Nucleotide-binding Palmitate Reference proteome Transducer | MTLESMMACC | MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMVRAMETLKILYKYEQNKANALLIREVDVEKVTTFEHQYVNAIKTLWSDPGVQECYDRRREFQLSDSAKYYLTDVDRIATVGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILHSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDS... | action potential adenylate cyclase-modulating G protein-coupled receptor signaling pathway cellular response to pH cranial skeletal system development developmental pigmentation endothelin receptor signaling pathway G protein-coupled receptor signaling pathway heart development ion channel modulating, G protein-coupled... |
ATP metabolic process proton transmembrane transport regulation of macroautophagy synaptic vesicle lumen acidification vacuolar acidification | apical plasma membrane; clathrin-coated vesicle membrane; cytosol; extracellular exosome; extrinsic component of synaptic vesicle membrane; intracellular membrane-bounded organelle; lysosomal membrane; melanosome; microvillus; plasma membrane; ruffle; vacuolar proton-transporting V-type ATPase, V1 domain | ATP binding proton transmembrane transporter activity proton-transporting ATPase activity, rotational mechanism | Homo sapiens | 3D-structure ATP-binding Cell membrane Cytoplasm Cytoplasmic vesicle Deafness Disease variant Hydrogen ion transport Ion transport Membrane Nucleotide-binding Reference proteome Synapse Transport | MALRAMRGIV | MALRAMRGIVNGAAPELPVPTGGPAVGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGR... | ATP metabolic process proton transmembrane transport regulation of macroautophagy synaptic vesicle lumen acidification vacuolar acidification apical plasma membrane; clathrin-coated vesicle membrane; cytosol; extracellular exosome; extrinsic component of synaptic vesicle membrane; intracellular membrane-bounded organel... |
proton transmembrane transport regulation of macroautophagy synaptic vesicle lumen acidification | apical part of cell; clathrin-coated vesicle membrane; cytosol; extracellular exosome; extrinsic component of synaptic vesicle membrane; lysosomal membrane; plasma membrane; proton-transporting two-sector ATPase complex; transmembrane transporter complex; vacuolar proton-transporting V-type ATPase, V1 domain | proton-transporting ATPase activity, rotational mechanism | Homo sapiens | 3D-structure Acetylation Cytoplasmic vesicle Direct protein sequencing Hydrogen ion transport Ion transport Membrane Reference proteome Synapse Transport | MTEFWLISAP | MTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGVVKKVAQYMADVLEDSKDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSEYLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHKARENKFIVRDFQYNEEEMKADKEEMNRLSTDKKKQFGPLVRWLKVNFSEAFIAWIHVKALRVFVESVLRYGLPVNFQAML... | proton transmembrane transport regulation of macroautophagy synaptic vesicle lumen acidification apical part of cell; clathrin-coated vesicle membrane; cytosol; extracellular exosome; extrinsic component of synaptic vesicle membrane; lysosomal membrane; plasma membrane; proton-transporting two-sector ATPase complex; tr... |
muscle tissue development platelet aggregation sarcomere organization | cytoplasm; extracellular exosome; focal adhesion; nucleus; Z disc | actinin binding RNA binding structural constituent of muscle zinc ion binding | Homo sapiens | Acetylation Isopeptide bond LIM domain Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation Zinc | MPNWGGGKKC | MPNWGGGKKCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYCKSCYGKKYGPKGYGYGQGAGTLSTDKGESLGIKHEEAPGHRPTTNPNASKFAQKIGGSERCPRCSQAVYAAEKVIGAGKSWHKACFRCAKCGKGLESTTLADKDGEIYCKGCYAKNFGPKGFGFGQGAGALVHSE | muscle tissue development platelet aggregation sarcomere organization cytoplasm; extracellular exosome; focal adhesion; nucleus; Z disc actinin binding RNA binding structural constituent of muscle zinc ion binding Homo sapiens Acetylation Isopeptide bond LIM domain Metal-binding Nucleus Phosphoprotein Reference proteom... |
cellular lipid metabolic process | cytosol; extracellular region; lysosome; mitochondrion | alcohol dehydrogenase (NADP+) activity alditol:NADP+ 1-oxidoreductase activity estradiol 17-beta-dehydrogenase activity geranylgeranyl reductase activity indanol dehydrogenase activity NADP-retinol dehydrogenase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor prostaglandi... | Mus musculus | Cytoplasm NADP Oxidoreductase Reference proteome | MATFVELSTK | MATFVELSTKAKMPLVGLGTWKSSPGQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIKENAVKREDLFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQAGNALLPKDNKGKVLLSKSTFLDAWEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHPYLTQEKLIQYCQSKGIAVTAYSPLGSPDRPYAKPEDPVVMEIPKIKEIAAKHKKTVAQVLIRFHVQRNVVVIPKSVTPSRIQENLQVFDFQLSEEDMAAILSFNRNWRACDLLDARTEEDYPFHEEY | cellular lipid metabolic process cytosol; extracellular region; lysosome; mitochondrion alcohol dehydrogenase (NADP+) activity alditol:NADP+ 1-oxidoreductase activity estradiol 17-beta-dehydrogenase activity geranylgeranyl reductase activity indanol dehydrogenase activity NADP-retinol dehydrogenase activity oxidoreduc... |
proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis | mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase, central stalk; mitochondrion; proton-transporting ATP synthase complex, catalytic core F(1) | proton-transporting ATP synthase activity, rotational mechanism | Saccharomyces cerevisiae | 3D-structure ATP synthesis CF(1) Direct protein sequencing Hydrogen ion transport Ion transport Membrane Mitochondrion Mitochondrion inner membrane Phosphoprotein Reference proteome Transport | MSAWRKAGIS | MSAWRKAGISYAAYLNVAAQAIRSSLKTELQTASVLNRSQTDAFYTQYKNGTAASEPTPITK | proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase, central stalk; mitochondrion; proton-transporting ATP synthase complex, catalytic core F(1... |
histidine catabolic process to glutamate and formamide histidine catabolic process to glutamate and formate | cytoplasm | histidine ammonia-lyase activity | Pseudomonas putida | 3D-structure Cytoplasm Direct protein sequencing Histidine metabolism Lyase | MTELTLKPGT | MTELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGASGDLAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNCDKVQDPYSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAA... | histidine catabolic process to glutamate and formamide histidine catabolic process to glutamate and formate cytoplasm histidine ammonia-lyase activity Pseudomonas putida 3D-structure Cytoplasm Direct protein sequencing Histidine metabolism Lyase MTELTLKPGT MTELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLL... |
RNA catabolic process | cytoplasm; outer membrane-bounded periplasmic space | Enterobacter ribonuclease activity ribonuclease T2 activity RNA binding | Escherichia coli | 3D-structure Cytoplasm Direct protein sequencing Disulfide bond Endonuclease Hydrolase Lyase Nuclease Periplasm Reference proteome Signal | MKAFWRNAAL | MKAFWRNAALLAVSLLPFSSANALALQAKQYGDFDRYVLALSWQTGFCQSQHDRNRNERDECRLQTETTNKADFLTVHGLWPGLPKSVAARGVDERRWMRFGCATRPIPNLPEARASRMCSSPETGLSLETAAKLSEVMPGAGGRSCLERYEYAKHGACFGFDPDAYFGTMVRLNQEIKESEAGKFLADNYGKTVSRRDFDAAFAKSWGKENVKAVKLTCQGNPAYLTEIQISIKADAINAPLSANSFLPQPHPGNCGKTFVIDKAGY | RNA catabolic process cytoplasm; outer membrane-bounded periplasmic space Enterobacter ribonuclease activity ribonuclease T2 activity RNA binding Escherichia coli 3D-structure Cytoplasm Direct protein sequencing Disulfide bond Endonuclease Hydrolase Lyase Nuclease Periplasm Reference proteome Signal MKAFWRNAAL MKAFWRNA... |
pyridine nucleotide salvage | cytosol | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides metal ion binding nicotinamidase activity | Escherichia coli | Hydrolase Metal-binding Pyridine nucleotide biosynthesis Reference proteome Zinc | MPPRALLLVD | MPPRALLLVDLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFASQHGVEPYTPGQLDGLPQTFWPDHCVQNSEGAQLHPLLHQKAIAAVFHKGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYKVNVITDGCRGVNIQPQDSAHAFMEMSAAGATLYTLADWEETQG | pyridine nucleotide salvage cytosol hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides metal ion binding nicotinamidase activity Escherichia coli Hydrolase Metal-binding Pyridine nucleotide biosynthesis Reference proteome Zinc MPPRALLLVD MPPRALLLVDLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRGE... |
mRNA branch site recognition mRNA splicing, via spliceosome | commitment complex; nucleus | ATP binding ATP hydrolysis activity ATP-dependent activity, acting on RNA nucleic acid binding RNA helicase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Coiled coil Helicase Hydrolase mRNA processing mRNA splicing Nucleotide-binding Nucleus Reference proteome | METIDSKQNI | METIDSKQNINRESLLEERRKKLAKWKQKKAQFDAQKEHQTSRNDIVTNSLEGKQTTEKFTERQERVKEELRKRKNEFRKSDEPVSVKPSKKKSKRSKVKKKISFDFSDDDDSEIGVSFRSKEHIQKAPEHDNEKDPLDEFMTSLKEEKMSNSKGMYDRGDILDVEDQLFELGGTDDEDVEDNTDNSNIAKIAKLKAKKRVKQIYYSPEELEPFQKNFYIESETVSSMSEMEVEELRLSLDNIKIKGTGCPKPVTKWSQLGLSTDTMVLITEKLHFGSLTPIQSQALPAIMSGRDVIGISKTGSGKTISYLLPLLRQVKA... | mRNA branch site recognition mRNA splicing, via spliceosome commitment complex; nucleus ATP binding ATP hydrolysis activity ATP-dependent activity, acting on RNA nucleic acid binding RNA helicase activity Saccharomyces cerevisiae 3D-structure ATP-binding Coiled coil Helicase Hydrolase mRNA processing mRNA splicing Nuc... |
intracellular iron ion homeostasis NAD metabolic process NADP biosynthetic process phosphorylation | cytoplasm; nucleus | ATP binding NAD+ kinase activity NADH kinase activity | Saccharomyces cerevisiae | ATP-binding Kinase NAD NADP Nucleotide-binding Phosphoprotein Reference proteome Transferase | MKENDMNNGV | MKENDMNNGVDKWVNEEDGRNDHHNNNNNLMKKAMMNNEQIDRTQDIDNAKEMLRKISSESSSRRSSLLNKDSSLVNGNANSGGGTSINGTRGSSKSSNTHFQYASTAYGVRMLSKDISNTKVELDVENLMIVTKLNDVSLYFLTRELVEWVLVHFPRVTVYVDSELKNSKKFAAGELCEDSKCRESRIKYWTKDFIREHDVFFDLVVTLGGDGTVLFVSSIFQRHVPPVMSFSLGSLGFLTNFKFEHFREDLPRIMNHKIKTNLRLRLECTIYRRHRPEVDPNTGKKICVVEKLSTHHILNEVTIDRGPSPFLSMLELY... | intracellular iron ion homeostasis NAD metabolic process NADP biosynthetic process phosphorylation cytoplasm; nucleus ATP binding NAD+ kinase activity NADH kinase activity Saccharomyces cerevisiae ATP-binding Kinase NAD NADP Nucleotide-binding Phosphoprotein Reference proteome Transferase MKENDMNNGV MKENDMNNGVDKWVNEED... |
FAD metabolic process protein folding in endoplasmic reticulum | endoplasmic reticulum; mitochondrion | FMN binding fumarate reductase (NADH) activity | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing FAD Flavoprotein Mitochondrion NAD Oxidoreductase Reference proteome Transit peptide | MIRSVRRVFI | MIRSVRRVFIYVSIFVLIIVLKRTLSGTDQTSMKQPVVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGGNSIKASSGINGAHTDTQQNLKVMDTPELFLKDTLHSAKGRGVPSLMDKLTKESKSAIRWLQTEFDLKLDLLAQLGGHSVPRTHRSSGKLPPGFEIVQALSKKLKDISSKDSNLVQIMLNSEVVDIELDNQGHVTGVVYMDENGNRKIMKSHHVVFCSGGFGYSKEMLKEYSPNLIHLPTTNGKQTTGDGQKILSKLGAELIDMDQVQVHPTGFIDPNDRENNWKFLAAEALRGLGGILLHPTTGRRFT... | FAD metabolic process protein folding in endoplasmic reticulum endoplasmic reticulum; mitochondrion FMN binding fumarate reductase (NADH) activity Saccharomyces cerevisiae 3D-structure Direct protein sequencing FAD Flavoprotein Mitochondrion NAD Oxidoreductase Reference proteome Transit peptide MIRSVRRVFI MIRSVRRVFIYV... |
aromatic compound catabolic process | plasma membrane | 2 iron, 2 sulfur cluster binding ferredoxin-NAD+ reductase activity metal ion binding | Pseudomonas putida | 2Fe-2S Aromatic hydrocarbons catabolism Cell inner membrane Cell membrane Direct protein sequencing FAD Flavoprotein Iron Iron-sulfur Membrane Metal-binding NAD Oxidoreductase Plasmid | MNEFFKKISG | MNEFFKKISGLFVPPPESTVSVRGQGFQFKVPRGQTILESALHQGIAFPHDCKVGSCGTCKYKLISGRVNELTSSAMGLSGDLYQSGYRLGCQCIPKEDLEIELDTVLGQALVPIETSALISKQKRLAHDIVEMEVVPDKQIAFYPGQYADVECAECSAVRSYSFSAPPQPDGSLSFHVRLVPGGVFSGWLFGGDRTGATLTLRAPYGQFGLHESNATMVCVAGGTGLAPIKCVLQSMTQAQRERDVLLFFGARQQRDLYCLDEIEALQLDWGGRFELIPVLSEESSTSSWKGKRGMVTEYFKEYLTGQPYEGYLCGPPP... | aromatic compound catabolic process plasma membrane 2 iron, 2 sulfur cluster binding ferredoxin-NAD+ reductase activity metal ion binding Pseudomonas putida 2Fe-2S Aromatic hydrocarbons catabolism Cell inner membrane Cell membrane Direct protein sequencing FAD Flavoprotein Iron Iron-sulfur Membrane Metal-binding NAD Ox... |
catecholamine catabolic process dopamine catabolic process phenylethylamine metabolic process positive regulation of signal transduction serotonin metabolic process | mitochondrial outer membrane; mitochondrion | aliphatic amine oxidase activity flavin adenine dinucleotide binding monoamine oxidase activity phenethylamine:oxygen oxidoreductase (deaminating) activity primary amine oxidase activity serotonin binding | Rattus norvegicus | 3D-structure Acetylation Catecholamine metabolism FAD Flavoprotein Membrane Mitochondrion Mitochondrion outer membrane Neurotransmitter degradation Oxidoreductase Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MTDLEKPNLA | MTDLEKPNLAGHMFDVGLIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLAYLDYNNLWRTMDEMGKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDY... | catecholamine catabolic process dopamine catabolic process phenylethylamine metabolic process positive regulation of signal transduction serotonin metabolic process mitochondrial outer membrane; mitochondrion aliphatic amine oxidase activity flavin adenine dinucleotide binding monoamine oxidase activity phenethylamine:... |
biogenic amine metabolic process dopamine catabolic process positive regulation of signal transduction | cytosol; mitochondrial outer membrane; mitochondrion | aliphatic amine oxidase activity flavin adenine dinucleotide binding monoamine oxidase activity phenethylamine:oxygen oxidoreductase (deaminating) activity primary amine oxidase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Catecholamine metabolism Direct protein sequencing Disease variant FAD Flavoprotein Intellectual disability Membrane Mitochondrion Mitochondrion outer membrane Neurotransmitter degradation Oxidoreductase Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MENQEKASIA | MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDY... | biogenic amine metabolic process dopamine catabolic process positive regulation of signal transduction cytosol; mitochondrial outer membrane; mitochondrion aliphatic amine oxidase activity flavin adenine dinucleotide binding monoamine oxidase activity phenethylamine:oxygen oxidoreductase (deaminating) activity primary ... |
catecholamine metabolic process | mitochondrial outer membrane; mitochondrion | aliphatic amine oxidase activity flavin adenine dinucleotide binding monoamine oxidase activity phenethylamine:oxygen oxidoreductase (deaminating) activity primary amine oxidase activity | Bos taurus | Acetylation Catecholamine metabolism FAD Flavoprotein Membrane Mitochondrion Mitochondrion outer membrane Neurotransmitter degradation Oxidoreductase Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MESLQKTSDA | MESLQKTSDAGQMFDVVVIGGGISGLSAAKLLAEHEVNVLVLEARERVGGRTYTVRNEHVDYVDVGGAYVGPTQNRILRLSKQLGLETYKVNVNERLVHYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTMDNMGKEIPADAPWEAPHAVEWDKMTMKDLIEKICWTKTARQFASLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSITNGGQERKFVGGSGQVSERIMQLLGDRVKLRSPVTYVDQSSENITVETLNRELYECRYVISAIPPTLTAKIHFRPELPSERNQLIQRLPMGAVIKCMMYYKEAFWKKKDY... | catecholamine metabolic process mitochondrial outer membrane; mitochondrion aliphatic amine oxidase activity flavin adenine dinucleotide binding monoamine oxidase activity phenethylamine:oxygen oxidoreductase (deaminating) activity primary amine oxidase activity Bos taurus Acetylation Catecholamine metabolism FAD Flavo... |
citrate metabolic process intestinal absorption intracellular iron ion homeostasis post-embryonic development regulation of translation response to iron(II) ion tricarboxylic acid cycle | cytoplasm; cytosol; endoplasmic reticulum; extracellular exosome; Golgi apparatus; mitochondrion | 3 iron, 4 sulfur cluster binding 4 iron, 4 sulfur cluster binding aconitate hydratase activity iron-responsive element binding metal ion binding RNA binding | Homo sapiens | 3D-structure 4Fe-4S Cytoplasm Direct protein sequencing Iron Iron-sulfur Lyase Metal-binding Phosphoprotein Reference proteome RNA-binding Tricarboxylic acid cycle | MSNPFAHLAE | MSNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDIENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPADLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQVNLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLPQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMCPEYGATAAFFPVDEVSITYL... | citrate metabolic process intestinal absorption intracellular iron ion homeostasis post-embryonic development regulation of translation response to iron(II) ion tricarboxylic acid cycle cytoplasm; cytosol; endoplasmic reticulum; extracellular exosome; Golgi apparatus; mitochondrion 3 iron, 4 sulfur cluster binding 4 ir... |
DNA-templated transcription proteolysis viral RNA genome replication | host cell membrane; membrane | nucleotide binding RNA binding RNA-dependent RNA polymerase activity serine-type endopeptidase activity | Southern cowpea mosaic virus ) | Covalent protein-RNA linkage Host membrane Hydrolase Membrane Nucleotide-binding Nucleotidyltransferase Protease Reference proteome Ribosomal frameshifting RNA-directed RNA polymerase Serine protease Transferase Transmembrane Transmembrane helix Viral RNA replication | MYRPSCLSYV | MYRPSCLSYVLLVANMWSFAVCANAFIYGSYDPSHNIPIVALMTLCATGLWLSTSVVSFGIRYVRVRVSPEKTQNRTIYVSSGLPHFDPVYGVVKKCEPMGGGPAIELQVNPSWIHLLPTSPAINKVEVGQESAILGSTYSVVETGGEPKSLVAVKSGDSTLGFGARVYHEGMDVLMVPHHVWYNDKPHTALAKNGRSVDTEDWEVEAACADPRIDFVLVKVPTAVWAKLAVRSTKVLAPVHGTAVQTFGGQDSKQLFSGLGKAKALDNAWEFTHTAPTAKGWSGTPLYTRDGIVGMHTGYVDIGTSNRAINMHFIMSCL... | DNA-templated transcription proteolysis viral RNA genome replication host cell membrane; membrane nucleotide binding RNA binding RNA-dependent RNA polymerase activity serine-type endopeptidase activity Southern cowpea mosaic virus )Covalent protein-RNA linkage Host membrane Hydrolase Membrane Nucleotide-binding Nucleo... |
nucleotide metabolic process proteolysis viral process | viral nucleocapsid | aspartic-type endopeptidase activity DNA binding dUTP diphosphatase activity structural constituent of virion zinc ion binding | Squirrel monkey retrovirus | Aspartyl protease Capsid protein Direct protein sequencing DNA-binding Hydrolase Lipoprotein Magnesium Myristate Nucleotide metabolism Protease Ribosomal frameshifting Viral matrix protein Viral nucleoprotein Virion | MGQASSHSEN | MGQASSHSENDLFISHLKESLKVRRIRVRKKDLVSFFSFIFKTCPWFPQEGSIDSRVWGRVGDCLNDYYRVFGPETIPITTFNYYNLIRDVLTNQSDSPDIQRLCKEGHKILISHSRPPSRQAPVTITTSEKASSRPPSRAPSTCPSVAIDIGSHDTGQSSLYPNLATLTDPPIQSPHSRAHTPPQHLPLLANSKTLHNSGSQDDQLNPADQADLEEAAAQYNNPDWPQLTNTPALPPFRPPSYVSTAVPPVAVAAPVLHAPTSGVPGSPTAPNLPGVALAKPSGPIDETVSLLDGVKTLVTKLSDLALLPPAGVMAFPV... | nucleotide metabolic process proteolysis viral process viral nucleocapsid aspartic-type endopeptidase activity DNA binding dUTP diphosphatase activity structural constituent of virion zinc ion binding Squirrel monkey retrovirus Aspartyl protease Capsid protein Direct protein sequencing DNA-binding Hydrolase Lipoprotei... |
viral budding via host ESCRT complex | host cell late endosome membrane; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid | RNA binding structural constituent of virion zinc ion binding | Gibbon ape leukemia virus | Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-fing... | MGQDNSTPIS | MGQDNSTPISLTLNHWRDVRTRAHNLSVEIKKGKWQTFCSSEWPTFGVGWPPEGTFNLSVIFAVKKIVFQENGGHPDQVPYIVVWQDLAQNPPPWVPASAKVAVVSDTRRPVAGRPSAPPRPPIYPATDDLLLLSEPTPPPYPAALPPPLAPQAIGPPSGQMPDSSDPEGPAAGTRSRRARSPADNSGPDSTVILPLRAIGPPAEPNGLVPLQYWPFSSADLYNWKSNHPSFSENPAGLTGLLESLMFSHQPTWDDCQQLLQILFTTEERERILLEARKNVLGDNGAPTQLENLINEAFPLNRPHWDYNTAAGRERLLVY... | viral budding via host ESCRT complex host cell late endosome membrane; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid RNA binding structural constituent of virion zinc ion binding Gibbon ape leukemia virus Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Ho... |
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane | host cell plasma membrane; membrane; virion membrane | monoatomic ion channel activity proton transmembrane transporter activity | Influenza A virus | Alternative splicing Disulfide bond Glycoprotein Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel Virion | MSLLTEVETP | MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDHLFFKCIYRFFKHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE | protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane host cell plasma membrane; membrane; virion membrane monoatomic ion channel activity proton transmembrane transporter activity Influenza A virus Alternative splicing Disulfide bond Glycoprotein Hos... |
viral budding via host ESCRT complex | host cell late endosome membrane; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid | RNA binding structural constituent of virion zinc ion binding | Hortulanus murine leukemia virus | Capsid protein Coiled coil Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger | MGQTITTPLS | MGQTITTPLSLTLDHWRDVQRIASNQSVDVKKRRWVTFCSAEWPTFNVGWPQDGTFNKDIITQVKIKVFSPGPHGHPDQVPYIVTWEAIAYDPPPWAKPFVHPQLSVSPSAPSAFSHEVSGPPTRSSLYPALTPTKSPSPKTQVLSDDGGPLIDLLSDDPPPYRGPENQPPAGRPTTTMQEMPRLPLKVPQEPSPMASRLRGRREHPAADSTTSQAFPLRTGGNGQLQYWPFSSADLYNWKNNNPSFSEDPGKLTALIESVLITHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGNDGRPTQLPNEINDAFPLERPD... | viral budding via host ESCRT complex host cell late endosome membrane; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid RNA binding structural constituent of virion zinc ion binding Hortulanus murine leukemia virus Capsid protein Coiled coil Host cell membrane Host endosome Host membra... |
fusion of virus membrane with host plasma membrane viral entry into host cell virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | metal ion binding | Hortulanus murine leukemia virus | Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host cell membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Palmitate Signal Transmembrane Transmembrane helix Viral atta... | MDRPALPKSI | MDRPALPKSIKDKTNPWGPIILGILIMLGGALGKGSPHKVFNLTWEVYNQEYETVWATSGSHPLWTWWPTLTPDLCMLAQLAKPSWGLSDYPPYSKPPGPPCCTTDNNPPGCSRDCNGPLTYLTPRCSTAWNRLKLVLTTHHLNQGFYVCPGPHRPRHARNCGGPDDFYCAHWGCETTGQAYWKPSSSWDYIRVSNNASSSDATTACKNNNWCSPLAISFTDPGKRATSWTSGFTWGLRLYISGHPGLIFGVRLKISDLGPRVPIGPNPVLSEQRPPSQPEPARLPPSSNLTQGGTPSAPTGPPQEGTGDRLLDLVQGAY... | fusion of virus membrane with host plasma membrane viral entry into host cell virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane metal ion binding Hortulanus murine leukemia virus Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane wit... |
intestine smooth muscle contraction muscle contraction negative regulation of luteinizing hormone secretion operant conditioning positive regulation of acetylcholine secretion, neurotransmission positive regulation of flagellated sperm motility positive regulation of monoatomic ion transport positive regulation of smoo... | plasma membrane; sperm flagellum; sperm head; sperm midpiece | substance K receptor activity tachykinin receptor activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MGTCDIVTEA | MGTCDIVTEANISSGPESNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATKCVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRL... | intestine smooth muscle contraction muscle contraction negative regulation of luteinizing hormone secretion operant conditioning positive regulation of acetylcholine secretion, neurotransmission positive regulation of flagellated sperm motility positive regulation of monoatomic ion transport positive regulation of smoo... |
phototransduction regulation of calcium ion transport visual perception | cytosol; membrane; perikaryon; photoreceptor inner segment; photoreceptor outer segment | calcium ion binding | Bos taurus | 3D-structure Calcium Cell projection Direct protein sequencing Disulfide bond Lipoprotein Membrane Metal-binding Myristate Oxidation Redox-active center Reference proteome Repeat Sensory transduction Vision | MGNSKSGALS | MGNSKSGALSKEILEELQLNTKFTEEELSSWYQSFLKECPSGRITRQEFQTIYSKFFPEADPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVTAIFKMISPEDTKHLPEDENTPEKRAEKIWGFFGKKDDDKLTEKEFIEGTLANKEILRLIQFEPQKVKEKLKEKKL | phototransduction regulation of calcium ion transport visual perception cytosol; membrane; perikaryon; photoreceptor inner segment; photoreceptor outer segment calcium ion binding Bos taurus 3D-structure Calcium Cell projection Direct protein sequencing Disulfide bond Lipoprotein Membrane Metal-binding Myristate Oxidat... |
cell division chromosome segregation sporulation resulting in formation of a cellular spore | plasma membrane | ATP binding ATP hydrolysis activity DNA binding | Bacillus subtilis | ATP-binding Cell cycle Cell division Cell membrane Chromosome partition DNA-binding Membrane Nucleotide-binding Reference proteome Sporulation Transmembrane Transmembrane helix | MAKKKRKSRK | MAKKKRKSRKKQAKQLNIKYELNGLLCIAISIIAILQLGVVGQTFIYLFRFFAGEWFILCLLGLLVLGVSLFWKKKTPSLLTRRKAGLYCIIASILLLSHVQLFKNLTHKGSIESASVVRNTWELFLMDMNGSSASPDLGGGMIGALLFAASHFLFASTGSQIMAIVMILIGMILVTGRSLQETLKKWMSPIGRFIKEQWLAFIDDMKSFKSNMQSSKKTKAPSKKQKPARKKQQMEPEPPDEEGDYETVSPLIHSEPIISSFSDRNEEEESPVIEKRAEPVSKPLQDIQPETGDQETVSAPPMTFTELENKDYEMPSLD... | cell division chromosome segregation sporulation resulting in formation of a cellular spore plasma membrane ATP binding ATP hydrolysis activity DNA binding Bacillus subtilis ATP-binding Cell cycle Cell division Cell membrane Chromosome partition DNA-binding Membrane Nucleotide-binding Reference proteome Sporulation Tra... |
cellular response to oxidative stress defense response negative regulation of blood vessel remodeling negative regulation of collagen catabolic process negative regulation of elastin catabolic process negative regulation of extracellular matrix disassembly negative regulation of proteolysis positive regulation of cell ... | axon; basement membrane; cell projection; collagen-containing extracellular matrix; contractile fiber; cytoplasm; extracellular region; extracellular space; Golgi apparatus; multivesicular body; neuronal cell body; nuclear membrane; perinuclear region of cytoplasm; plasma membrane; vesicle | amyloid-beta binding cysteine-type endopeptidase inhibitor activity endopeptidase inhibitor activity identical protein binding peptidase inhibitor activity protease binding | Mus musculus | Disulfide bond Protease inhibitor Reference proteome Secreted Signal Thiol protease inhibitor | MASPLRSLLF | MASPLRSLLFLLAVLAVAWAATPKQGPRMLGAPEEADANEEGVRRALDFAVSEYNKGSNDAYHSRAIQVVRARKQLVAGVNYFLDVEMGRTTCTKSQTNLTDCPFHDQPHLMRKALCSFQIYSVPWKGTHSLTKFSCKNA | cellular response to oxidative stress defense response negative regulation of blood vessel remodeling negative regulation of collagen catabolic process negative regulation of elastin catabolic process negative regulation of extracellular matrix disassembly negative regulation of proteolysis positive regulation of cell ... |
enteroendocrine cell differentiation positive regulation of proteasomal ubiquitin-dependent protein catabolic process proteasomal protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process protein ubiquitination R7 cell fate commitment regulation of R7 cell differentiation sensory organ... | cytoplasm; cytosol; nucleus; ubiquitin ligase complex | identical protein binding ubiquitin conjugating enzyme binding ubiquitin protein ligase activity ubiquitin-protein transferase activity zinc ion binding | Drosophila melanogaster | Cytoplasm Developmental protein Metal-binding Nucleus Reference proteome Sensory transduction Transferase Ubl conjugation pathway Vision Zinc Zinc-finger | MSNKINPKRR | MSNKINPKRREPTAAAAGAGATGVATNTSTSTGSSSAGNTSSANTSSSSSSSLSSAGGGDAGMSADLTSLFECPVCFDYVLPPILQCSSGHLVCVSCRSKLTCCPTCRGPLANIRNLAMEKVASNVKFPCKHSGYGCTASLVYTEKTEHEETCECRPYLCPCPGASCKWQGPLDLVMQHLMMSHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYDGHQQFFAIVQLIGSRKEAENFVYRLELNGNRRRLTWEAMPRSIHEGVASAIHNSDCLVFDTSIAQLFADNGNLGINVTISLV | enteroendocrine cell differentiation positive regulation of proteasomal ubiquitin-dependent protein catabolic process proteasomal protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process protein ubiquitination R7 cell fate commitment regulation of R7 cell differentiation sensory organ... |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway chemotaxis complement receptor mediated signaling pathway G protein-coupled receptor signaling pathway inflammatory response nitric oxide mediated signal transduction phospholipase C-activating G protein-coupled receptor signaling pathway positiv... | azurophil granule membrane; cytoplasm; ficolin-1-rich granule membrane; membrane; plasma membrane; secretory granule membrane | complement receptor activity G protein-coupled receptor activity G protein-coupled receptor binding N-formyl peptide receptor activity RAGE receptor binding scavenger receptor binding | Homo sapiens | 3D-structure Cell membrane Chemotaxis Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | METNSSLPTN | METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASL... | adenylate cyclase-modulating G protein-coupled receptor signaling pathway chemotaxis complement receptor mediated signaling pathway G protein-coupled receptor signaling pathway inflammatory response nitric oxide mediated signal transduction phospholipase C-activating G protein-coupled receptor signaling pathway positiv... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway adult locomotory behavior B cell differentiation cell surface receptor signaling pathway cellular response to glycoprotein cellular response to thyrotropin-releasing hormone cochlea morphogenesis dopaminergic neuron differentiation hormone-mediat... | basolateral plasma membrane; plasma membrane; receptor complex | G protein-coupled peptide receptor activity protein-containing complex binding signaling receptor activity thyroid-stimulating hormone receptor activity | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Leucine-rich repeat Membrane Receptor Reference proteome Repeat Signal Sulfation Transducer Transmembrane Transmembrane helix | MRPGSLLQLT | MRPGSLLQLTLLLALPRSLWGRGCTSPPCECHQEDDFRVTCKELHQIPSLPPSTQTLKLIETHLKTIPSLAFSSLPNISRIYLSIDATLQRLEPHSFYNLSKMTHIEIRNTRSLTYIDPDALTELPLLKFLGIFNTGLRIFPDLTKIYSTDVFFILEITDNPYMTSVPENAFQGLCNETLTLKLYNNGFTSIQGHAFNGTKLDAVYLNKNKYLTAIDKDAFGGVYSGPTLLDVSSTSVTALPSKGLEHLKELIAKNTWTLKKLPLSLSFLHLTRADLSYPSHCCAFKNQKKIRGILESLMCNESSIRNLRQRKSVNVMRG... | adenylate cyclase-activating G protein-coupled receptor signaling pathway adult locomotory behavior B cell differentiation cell surface receptor signaling pathway cellular response to glycoprotein cellular response to thyrotropin-releasing hormone cochlea morphogenesis dopaminergic neuron differentiation hormone-mediat... |
response to antibiotic translation | ribosome; small ribosomal subunit | rRNA binding structural constituent of ribosome tRNA binding | Bacillus subtilis | 3D-structure Antibiotic resistance Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding tRNA-binding | MPTINQLIRK | MPTINQLIRKGRVSKVENSKSPALNKGYNSFKKEHTNVSSPQKRGVCTRVGTMTPKKPNSALRKYARVRLTNGIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVENRAQGRSKYGTKKPKAK | response to antibiotic translation ribosome; small ribosomal subunit rRNA binding structural constituent of ribosome tRNA binding Bacillus subtilis 3D-structure Antibiotic resistance Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding tRNA-binding MPTINQLIRK MPTINQL... |
mRNA catabolic process ncRNA processing response to cold | cytosol | 3'-5' RNA helicase activity 3'-5'-RNA exonuclease activity exoribonuclease II activity ribonuclease R activity RNA binding RNA exonuclease activity, producing 5'-phosphomonoesters RNA nuclease activity | Escherichia coli | Acetylation Cytoplasm Direct protein sequencing Exonuclease Hydrolase Nuclease Reference proteome RNA-binding Stress response Virulence | MSQDPFQERE | MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVELHIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPERLDLVKGTVIGHRDGYGFLRVEGRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEAGVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNMGTGMAVDIALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDARDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPSTPLDREARNRG... | mRNA catabolic process ncRNA processing response to cold cytosol 3'-5' RNA helicase activity 3'-5'-RNA exonuclease activity exoribonuclease II activity ribonuclease R activity RNA binding RNA exonuclease activity, producing 5'-phosphomonoesters RNA nuclease activity Escherichia coli Acetylation Cytoplasm Direct protein... |
ribosome biogenesis transcriptional attenuation | cytosol | ATP binding ATP hydrolysis activity ATP-dependent activity, acting on RNA poly(A) binding RNA helicase activity RNA strand annealing activity | Escherichia coli | 3D-structure ATP-binding Cytoplasm Helicase Hydrolase Nucleotide-binding Reference proteome Ribosome biogenesis RNA-binding | MTVTTFSELE | MTVTTFSELELDESLLEALQDKGFTRPTAIQAAAIPPALDGRDVLGSAPTGTGKTAAYLLPALQHLLDFPRKKSGPPRILILTPTRELAMQVSDHARELAKHTHLDIATITGGVAYMNHAEVFSENQDIVVATTGRLLQYIKEENFDCRAVETLILDEADRMLDMGFAQDIEHIAGETRWRKQTLLFSATLEGDAIQDFAERLLEDPVEVSANPSTRERKKIHQWYYRADDLEHKTALLVHLLKQPEATRSIVFVRKRERVHELANWLREAGINNCYLEGEMVQGKRNEAIKRLTEGRVNVLVATDVAARGIDIPDVSHV... | ribosome biogenesis transcriptional attenuation cytosol ATP binding ATP hydrolysis activity ATP-dependent activity, acting on RNA poly(A) binding RNA helicase activity RNA strand annealing activity Escherichia coli 3D-structure ATP-binding Cytoplasm Helicase Hydrolase Nucleotide-binding Reference proteome Ribosome biog... |
calcium ion-regulated exocytosis of neurotransmitter cellular response to calcium ion chemical synaptic transmission clathrin-dependent synaptic vesicle endocytosis larval locomotory behavior neurotransmitter secretion positive regulation of vesicle fusion regulation of calcium ion-dependent exocytosis regulation of do... | axon; dense core granule; exocytic vesicle; membrane; neuromuscular junction; plasma membrane; synaptic vesicle; synaptic vesicle membrane; terminal bouton | calcium ion binding calcium-dependent phospholipid binding clathrin binding phosphatidylserine binding protein homodimerization activity SNARE binding syntaxin binding | Drosophila melanogaster | Alternative splicing Calcium Cytoplasmic vesicle Membrane Metal-binding Reference proteome Repeat RNA editing Synapse Transmembrane Transmembrane helix | MPPNAKSETD | MPPNAKSETDAKPEAEPAPASEPAADLESVDQKLEETHHSKFREVDRQEQEVLAEKAAEAASQRIAQVESTTRSATTEAQESTTTAVPVIKKIEHVGEVVTEVIAERTGLPTWGVVAIIILVFLVVFGIIFFCVRRFLKKRRTKDGKGKKGVDMKSVQLLGSAYKEKVQPDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGE... | calcium ion-regulated exocytosis of neurotransmitter cellular response to calcium ion chemical synaptic transmission clathrin-dependent synaptic vesicle endocytosis larval locomotory behavior neurotransmitter secretion positive regulation of vesicle fusion regulation of calcium ion-dependent exocytosis regulation of do... |
deoxyribonucleotide biosynthetic process DNA replication | cytoplasm; nucleus; ribonucleoside-diphosphate reductase complex | ATP binding identical protein binding nucleotide binding ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | Saccharomyces cerevisiae | 3D-structure Allosteric enzyme ATP-binding Cytoplasm Deoxyribonucleotide synthesis Disulfide bond Isopeptide bond Nucleotide-binding Oxidoreductase Phosphoprotein Reference proteome Ubl conjugation | MYVYKRDGRK | MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLAAETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDVYNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHGRDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADIFDFIDIRKNHGK... | deoxyribonucleotide biosynthetic process DNA replication cytoplasm; nucleus; ribonucleoside-diphosphate reductase complex ATP binding identical protein binding nucleotide binding ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Saccharomyces cerevisiae 3D-structure Allosteric enzyme ATP... |
collateral sprouting of injured axon compound eye development dendrite morphogenesis dorsal closure embryo development ending in birth or egg hatching establishment or maintenance of cell polarity follicle cell of egg chamber migration G2/M transition of mitotic cell cycle germ cell development imaginal disc fusion, th... | cytoplasm; nucleoplasm; nucleus; transcription factor AP-1 complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding protein heterodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Drosophila melanogaster | Activator Alternative promoter usage Alternative splicing Direct protein sequencing DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MKNLNGRTHN | MKNLNGRTHNACYHPYYHQSLHFAQQQQQQQQHHLQQQQQHMQQQQQQQQAPQQQLRHQQRQLPTQPAYQQSQSVAHNAFPLRSSSNNYGHVASSAYAASSGSHNSNNAAAMAAVCQMQNFFNQQQQQQQQLEFNNNCMPINYYQQQQQQHYPSESQSSASGWNPETPGQAQLALTATTCNTTAAATCNTTAAATTSTTATSAAAGSDNNHSDNFAMDASEIATFLANELFLQQLGNFETGQSVLTLTTPTLTPTTTRNIEDTLGHLLSDTQTDRVAGCAGFAVPKVLPNAIDVLGMGIPTGVSSLPLQQTFDLSLGQGS... | collateral sprouting of injured axon compound eye development dendrite morphogenesis dorsal closure embryo development ending in birth or egg hatching establishment or maintenance of cell polarity follicle cell of egg chamber migration G2/M transition of mitotic cell cycle germ cell development imaginal disc fusion, th... |
malate metabolic process | chloroplast | malate dehydrogenase (NADP+) activity | Pisum sativum | Chloroplast Direct protein sequencing Disulfide bond NADP Oxidoreductase Plastid Transit peptide | MALTQLNSTC | MALTQLNSTCSKPQLHSSSQLSFLSRTRTRTLPRHYHSTFAPLHRTQHARISCSVAPNQVQVPAAQTQDPKGKPDCYGVFCLTYDLKAEEETKSWKKLINIAVSGAAGMISNHLLFKLASGEVFGPDQPIALKLLGSERSIQALEGVAMELEDSLFPLLREVVISIDPYEVFQDAEWALLIGAKPRGPGVERAALLDINGQIFAEQGKALNAVASRNAKVIVVGNPCNTNALICLKNAPNIPAKNFHALTRLDENRAKCQLALKAGVFYDKVSNMTIWGNHSTTQVPDFLNARIDGLPVKEVIKDNKWLEEEFTEKVQKR... | malate metabolic process chloroplast malate dehydrogenase (NADP+) activity Pisum sativum Chloroplast Direct protein sequencing Disulfide bond NADP Oxidoreductase Plastid Transit peptide MALTQLNSTC MALTQLNSTCSKPQLHSSSQLSFLSRTRTRTLPRHYHSTFAPLHRTQHARISCSVAPNQVQVPAAQTQDPKGKPDCYGVFCLTYDLKAEEETKSWKKLINIAVSGAAGMISNHLLFKLASGE... |
proteolysis | extracellular region | serine-type carboxypeptidase activity | Hordeum vulgare | Carboxypeptidase Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Secreted Signal Zymogen | MVTTPRLVSL | MVTTPRLVSLLLLLALCAAAAGALRLPPDASFPGAQAERLIRALNLLPKDSSSSSGRHGARVGEGNEDVAPGQLLERRVTLPGLPEGVADLGHHAGYYRLPNTHDARMFYFFFESRGKKEDPVVIWLTGGPGCSSELAVFYENGPFTIANNMSLVWNKFGWDKISNIIFVDQPTGTGFSYSSDDRDTRHDETGVSNDLYDFLQVFFKKHPEFIKNDFFITGESYAGHYIPAFASRVHQGNKKNEGTHINLKGFAIGNGLTDPAIQYKAYTDYALEMNLIQKADYERINKFIPPCEFAIKLCGTNGKASCMAAYMVCNTIF... | proteolysis extracellular region serine-type carboxypeptidase activity Hordeum vulgare Carboxypeptidase Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Secreted Signal Zymogen MVTTPRLVSL MVTTPRLVSLLLLLALCAAAAGALRLPPDASFPGAQAERLIRALNLLPKDSSSSSGRHGARVGEGNEDVAPGQLLERRVTLPGLPEGVADLGHHAGYYRLPNTHDARM... |
cellular response to interleukin-4 translation | cytoplasm; cytosolic large ribosomal subunit; cytosolic ribosome; nucleolus; protein-containing complex; ribosome; synapse | 5S rRNA binding RNA binding structural constituent of ribosome | Rattus norvegicus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Methylation Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation | MSHRKFSAPR | MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREVDRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYKNWHKSKKKAFTKYCKKWQDDTGKKQLEKDFNSMKKYCQVIRIIAHTQMRLLPLRQKKAHLMEIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKLPRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIKNNASTDYDLSDKSINPLGGF... | cellular response to interleukin-4 translation cytoplasm; cytosolic large ribosomal subunit; cytosolic ribosome; nucleolus; protein-containing complex; ribosome; synapse 5S rRNA binding RNA binding structural constituent of ribosome Rattus norvegicus 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopepti... |
cytoplasmic translation | A band; cytoplasm; cytoplasmic ribonucleoprotein granule; cytosolic large ribosomal subunit; cytosolic ribosome; nucleus; polysomal ribosome; postsynaptic density; rough endoplasmic reticulum; synapse | 5.8S rRNA binding mRNA binding RNA binding structural constituent of ribosome tRNA binding | Rattus norvegicus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Endoplasmic reticulum Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation | MAGEKAEKPD | MAGEKAEKPDKKEQKPAAKKAGGDATAPRALPAGAVKKSSSKAKKLRKSKPHCSRNPVLVRGIGRYSRSAMYSRKALYKRKYSAAKTKVEKKKKKEKVLATVTKTVGGDKNGGTRVVKLRKMPRYYPTEDVPRKLLSHGKKPFSQHVRRLRSSITPGTVLIILTGRHRGKRVVFLKQLGSGLLLVTGPLALNRVPLRRTHQKFVIATSTKVDISKVKIPKHLTDAYFKKKPLRKPRHQEGEIFDTEKEKYEITEQRKADQKAVDSQILPKIKAVPQLQGYLRSQFSLTNGMYPHKLVF | cytoplasmic translation A band; cytoplasm; cytoplasmic ribonucleoprotein granule; cytosolic large ribosomal subunit; cytosolic ribosome; nucleus; polysomal ribosome; postsynaptic density; rough endoplasmic reticulum; synapse 5.8S rRNA binding mRNA binding RNA binding structural constituent of ribosome tRNA binding Ratt... |
positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II termination of RNA polymerase I transcription termination of RNA polymerase II transcription transcriptional start site selection at RNA polymerase II promoter | chromatin; nucleoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding transcription cis-regulatory region binding | Saccharomyces cerevisiae | DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation | MPSGHNDKNA | MPSGHNDKNANQESVEEAVLKYVGVGLDHQNHDPQLHTKDLENKHSKKQNIVESSSDVDVNNNDDSNRNEDNNDDSENISALNANESSSNVDHANSNEQHNAVMDWYLRQTAHNQQDDEDDENNNNTDNGNDSNNHFSQSDIVVDDDDDKNKKDAGVGVDDDHQSMAMAAVAAAYTLSKNNNNNNSIANDSNSRKRQHDNGNNHENSQKKRKNNNDDDDRQIGNVDPELTTLGDADDNDTNNDVIDRDQLVHKAIIDADSITQHPDFQQYLNTAADTDDNEKLKHIKDHLMRTHGLNHQNKNHNDDTDDLSNSTKQYSEL... | positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II termination of RNA polymerase I transcription termination of RNA polymerase II transcription transcriptional start site selection at RNA polymerase II promoter chromatin; ... |
anaphase-promoting complex-dependent catabolic process anterior/posterior axis specification, embryo embryo development ending in birth or egg hatching meiotic cell cycle positive regulation of metaphase/anaphase transition of meiotic cell cycle positive regulation of proteasomal ubiquitin-dependent protein catabolic p... | Cul2-RING ubiquitin ligase complex | cyclin binding | Caenorhabditis elegans | Developmental protein Meiosis Reference proteome Ubl conjugation pathway | MDHNAALTTC | MDHNAALTTCSTSAIPRLARLATERIAELIENDALPEFDHKVIASCSNDIFEVLRQKKKLNHQTLQTMCSTSRFQINKIDLMGNKVELQDLELCSNQNLVSFRLGDIDYFPNTNKIQVADVLDTALNRTSRQQLRHLDLSGRHRITSNWPTYVARKLPRLESLAFANRSTANETLSQIGASLLNLRFLDISSTCVTDISCISSLRNLEVLIMYNLNILKGDVTETLSNLTKLRVLDISRKVNTDYLQETSQDAHLDLALGIYNRSVEAIESGTATPWAELRAIDMSGLSIVQFGTDRALAFVEKIIEAHPKLEQISLLAT... | anaphase-promoting complex-dependent catabolic process anterior/posterior axis specification, embryo embryo development ending in birth or egg hatching meiotic cell cycle positive regulation of metaphase/anaphase transition of meiotic cell cycle positive regulation of proteasomal ubiquitin-dependent protein catabolic p... |
adult behavior cellular response to histamine chloride transmembrane transport gamma-aminobutyric acid signaling pathway inhibitory synapse assembly post-embryonic development regulation of postsynaptic membrane potential synaptic transmission, GABAergic | axon; chloride channel complex; dendrite membrane; GABA-A receptor complex; GABA-ergic synapse; neuron projection; plasma membrane; postsynapse; postsynaptic membrane; synapse | chloride channel activity GABA-A receptor activity GABA-gated chloride ion channel activity inhibitory extracellular ligand-gated monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Gallus gallus | Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Membrane Postsynaptic cell membrane Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MTPSNPTRLG | MTPSNPTRLGSTALLNPAFSLKMMVWALVFLSLIQCSTQKGDDDYEDYTSNKTWVLTPKVHESDVTLILNGLLEGYDNKLRPDIGVKPTVIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDAHSCPLEFSSYGYPREEIIYQWKRSSVEVGDTRSWRLYQFSFTGLRNTTEVVKTTSGDYVVMSVYFNLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTI... | adult behavior cellular response to histamine chloride transmembrane transport gamma-aminobutyric acid signaling pathway inhibitory synapse assembly post-embryonic development regulation of postsynaptic membrane potential synaptic transmission, GABAergic axon; chloride channel complex; dendrite membrane; GABA-A recepto... |
glycine biosynthetic process, by transamination of glyoxylate glyoxylate catabolic process glyoxylate metabolic process L-alanine catabolic process L-cysteine catabolic process L-serine metabolic process Notch signaling pathway oxalic acid secretion | cytosol; intracellular membrane-bounded organelle; peroxisomal matrix; peroxisome | alanine-glyoxylate transaminase activity amino acid binding identical protein binding protein homodimerization activity protein self-association pyridoxal phosphate binding serine-pyruvate transaminase activity transaminase activity | Homo sapiens | 3D-structure Acetylation Aminotransferase Disease variant Peroxisome Phosphoprotein Pyridoxal phosphate Reference proteome Transferase | MASHKLLVTP | MASHKLLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRNPLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIGARVHPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSFYLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHGRLQALGLQLFVKDPALRLPT... | glycine biosynthetic process, by transamination of glyoxylate glyoxylate catabolic process glyoxylate metabolic process L-alanine catabolic process L-cysteine catabolic process L-serine metabolic process Notch signaling pathway oxalic acid secretion cytosol; intracellular membrane-bounded organelle; peroxisomal matrix;... |
canonical glycolysis glycolytic process | cytosol; membrane; phosphopyruvate hydratase complex; plasma membrane | identical protein binding magnesium ion binding phosphopyruvate hydratase activity protein-containing complex binding | Mus musculus | Acetylation Cytoplasm Direct protein sequencing Glycolysis Lyase Magnesium Metal-binding Phosphoprotein Reference proteome | MAMQKIFARE | MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKARYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKNFIQNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDL... | canonical glycolysis glycolytic process cytosol; membrane; phosphopyruvate hydratase complex; plasma membrane identical protein binding magnesium ion binding phosphopyruvate hydratase activity protein-containing complex binding Mus musculus Acetylation Cytoplasm Direct protein sequencing Glycolysis Lyase Magnesium Meta... |
feeding behavior glucose metabolic process locomotory behavior negative regulation of cytosolic calcium ion concentration negative regulation of hormone secretion outflow tract morphogenesis peristalsis positive regulation of vasoconstriction regulation of blood pressure regulation of multicellular organism growth regu... | axon; glutamatergic synapse; neuron projection; neuronal dense core vesicle; plasma membrane; presynaptic membrane; synaptic vesicle | neuropeptide binding neuropeptide receptor activity neuropeptide Y receptor activity pancreatic polypeptide receptor activity peptide YY receptor activity | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MNSTLFSRVE | MNSTLFSRVENYSVHYNVSENSPFLAFENDDCHLPLAVIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAVMCLPFTFVYTLMDHWVFGETMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYIGITVIWVLAVASSLPFVIYQILTDEPFQNVSLAAFKDKYVCFDKFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKIRDSKYRSSETKRINVMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYG... | feeding behavior glucose metabolic process locomotory behavior negative regulation of cytosolic calcium ion concentration negative regulation of hormone secretion outflow tract morphogenesis peristalsis positive regulation of vasoconstriction regulation of blood pressure regulation of multicellular organism growth regu... |
mitochondrial respiratory chain complex III assembly positive regulation of mitochondrial translation protein stabilization | Cbp3p-Cbp6 complex; mitochondrial membrane; mitochondrial ribosome; mitochondrion | mRNA binding ribosome binding | Saccharomyces cerevisiae | Chaperone Membrane Mitochondrion Reference proteome Transit peptide Transmembrane Transmembrane helix | MMSVNRFTSG | MMSVNRFTSGRLPVFLRKSPFYYSRAYLHQTCVFKQNKETAQDSPELLAKSSHLNSKPLDVSNKAPVKTAQNKIPLAHSKYESSKYELPKWKEALGELVIRAFHLDMDRVRAGPVAGSYYYKICKEQGLQYEDEPLSETAKYFYEDLKLPRTFSQWFQITVLHEWILFVRMRAMPFKYGRNYQQKLVDRTFSDIELRLFEEMKVNSGRIADQYLKDFNTQLRGAIFAYDEGFATDDGTLATAVWRNLFGGRKNIDMVHLESVVRYIYSQLYVLSRLSDREFATGKFKFVPPGVKVEKLTPKQEEELKAKTIAKYEALDKD... | mitochondrial respiratory chain complex III assembly positive regulation of mitochondrial translation protein stabilization Cbp3p-Cbp6 complex; mitochondrial membrane; mitochondrial ribosome; mitochondrion mRNA binding ribosome binding Saccharomyces cerevisiae Chaperone Membrane Mitochondrion Reference proteome Transi... |
SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane, translocation | cytosol; endoplasmic reticulum; signal recognition particle, endoplasmic reticulum targeting | 7S RNA binding ATP hydrolysis activity endoplasmic reticulum signal peptide binding GTP binding GTPase activity | Schizosaccharomyces pombe | Cytoplasm Endoplasmic reticulum GTP-binding Hydrolase Nucleotide-binding Reference proteome Ribonucleoprotein RNA-binding Signal recognition particle | MVFADLGRRL | MVFADLGRRLNSALGDFSKATSVNEELVDTLLKNICTALLETDVNVRLVQELRSNIKKKINVSTLPQGINGKRIVQKAVFDELCSLVDPKVDAFTPKKGRPSVIMMVGLQGSGKTTTCSKLALHYQRRGLKSCLVAADTFRAGAFDQLKQNAIKARVPYFGSYTETDPVVIAKEGVDKFKNDRFDVIIVDTSGRHQQEQELFAEMVEISDAIRPDQTIMILDASIGQAAESQSKAFKETADFGAVIITKLDGHAKGGGALSAVAATKTPIVFIGTGEHINDLERFSPRSFISKLLGLGDLEGLMEHVQSLDFDKKNMVKN... | SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane, translocation cytosol; endoplasmic reticulum; signal recognition particle, endoplasmic reticulum targeting 7S RNA binding ATP hydrolysis activity endoplasmic reticulum signal peptide binding GTP bind... |
actin filament polymerization activation of phospholipase A2 activity activation of phospholipase C activity angiogenesis antibacterial humoral response antifungal humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cell differentiation cell migration central nervous system developm... | actin cytoskeleton; angiogenin-PRI complex; basement membrane; chromosome; cytoplasmic vesicle; extracellular region; extracellular space; growth cone; neuronal cell body; nucleolus; nucleus | actin binding copper ion binding DNA binding endonuclease activity heparin binding peptide binding protein homodimerization activity RNA binding RNA nuclease activity signaling receptor binding tRNA-specific ribonuclease activity | Mus musculus | 3D-structure Angiogenesis Cytoplasmic vesicle Developmental protein Differentiation Direct protein sequencing Disulfide bond DNA-binding Endonuclease Hydrolase Nuclease Nucleus Protein synthesis inhibitor Pyrrolidone carboxylic acid Reference proteome Secreted Signal Stress response | MAISPGPLFL | MAISPGPLFLIFVLGLVVIPPTLAQDDSRYTKFLTQHHDAKPKGRDDRYCERMMKRRSLTSPCKDVNTFIHGNKSNIKAICGANGSPYRENLRMSKSPFQVTTCKHTGGSPRPPCQYRASAGFRHVVIACENGLPVHFDESFFSL | actin filament polymerization activation of phospholipase A2 activity activation of phospholipase C activity angiogenesis antibacterial humoral response antifungal humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cell differentiation cell migration central nervous system developm... |
negative regulation of arachidonic acid secretion negative regulation of prostaglandin secretion positive regulation of blood pressure positive regulation of heart rate proton motive force-driven mitochondrial ATP synthesis response to muscle activity | cell surface; extracellular space; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) | protein-containing complex binding proton transmembrane transporter activity | Rattus norvegicus | Acetylation CF(0) Direct protein sequencing Hydrogen ion transport Ion transport Membrane Mitochondrion Mitochondrion inner membrane Phosphoprotein Reference proteome Transit peptide Transport | MTVQRIFRLS | MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS | negative regulation of arachidonic acid secretion negative regulation of prostaglandin secretion positive regulation of blood pressure positive regulation of heart rate proton motive force-driven mitochondrial ATP synthesis response to muscle activity cell surface; extracellular space; mitochondrial proton-transporting... |
cellular response to estradiol stimulus cellular response to glucocorticoid stimulus cellular response to oxygen levels cellular response to starvation cellular response to tumor necrosis factor myoblast fate determination myoblast fusion myotube differentiation involved in skeletal muscle regeneration negative regulat... | euchromatin; myofibril; nucleoplasm; transcription regulator complex | bHLH transcription factor binding chromatin DNA binding DNA-binding transcription activator activity DNA-binding transcription activator activity, RNA polymerase II-specific E-box binding nuclear receptor binding promoter-specific chromatin binding protein homodimerization activity ubiquitin protein ligase binding | Coturnix japonica | Activator Developmental protein Differentiation DNA-binding Myogenesis Nucleus Reference proteome Transcription Transcription regulation | MDLLGPMEMT | MDLLGPMEMTEGSLCSFAAADDFYDDPCFNTSDMHFFEDLDPRLVHVGGLLKPEEHPHHHGHHHGHPHEEEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSTNPNQRLPKVEILRNAIRYIESLQALLREQEDAYYPVLEHYSGESDASSPRSNCSDGMMEYSGPPCSSRRRNSYDSSYYTESPNDPKHGKSSVVSSLDCLSSIVERISTDNSTCPILPPAEAVAEGSPCSPQEGASLNDSGAQIPSPTNCTPLPQDSSSSSNPIYQVL | cellular response to estradiol stimulus cellular response to glucocorticoid stimulus cellular response to oxygen levels cellular response to starvation cellular response to tumor necrosis factor myoblast fate determination myoblast fusion myotube differentiation involved in skeletal muscle regeneration negative regulat... |
positive regulation of DNA-templated transcription | cytoplasm; ribonucleoprotein complex | RNA binding sequence-specific DNA binding | Xenopus laevis | Alternative splicing Cytoplasm Direct protein sequencing DNA-binding Phosphoprotein Reference proteome Ribonucleoprotein RNA-binding Transcription Transcription regulation | MSEAEAQEPE | MSEAEAQEPEPVPQPESEPEIQKPGIAAARNQANKKVLATQVQGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKFLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVKGSRFAPNRRRFRRRFYRPRADTAGESGGEGVSPEQMSEGERGEETSPQQRPQRRRPPPFFYRRRFRRGPRPNNQQNQGAEVTEQSENKDPVAPTSEALASGDDPQRPPPRRFRQRFRRPFRPRPAPQQTPEGGDGETKAESGEDPRPEPQRQRNRPYVQRRRRQGATQVAATAQGEGKAEPTQHPASEEGTPSDSPTDDGAPV... | positive regulation of DNA-templated transcription cytoplasm; ribonucleoprotein complex RNA binding sequence-specific DNA binding Xenopus laevis Alternative splicing Cytoplasm Direct protein sequencing DNA-binding Phosphoprotein Reference proteome Ribonucleoprotein RNA-binding Transcription Transcription regulation MSE... |
clathrin coat assembly involved in endocytosis endocytosis endosome organization G protein-coupled receptor internalization modulation of chemical synaptic transmission positive regulation of synaptic vesicle endocytosis positive regulation of synaptic vesicle recycling protein homooligomerization protein homotetrameri... | chromaffin granule; clathrin-coated pit; clathrin-coated vesicle; cytoplasm; endocytic vesicle; glutamatergic synapse; Golgi apparatus; membrane; membrane coat; microtubule; photoreceptor inner segment; photoreceptor ribbon synapse; plasma membrane; presynapse; presynaptic endocytic zone membrane; protein-containing co... | D2 dopamine receptor binding GDP binding GTP binding GTPase activity identical protein binding microtubule binding nitric-oxide synthase binding phosphatidylinositol-3,4,5-trisphosphate binding phosphatidylinositol-4,5-bisphosphate binding protein homodimerization activity protein kinase binding protein self-associatio... | Rattus norvegicus | 3D-structure Alternative splicing Cell membrane Cell projection Coated pit Cytoplasmic vesicle Direct protein sequencing Endocytosis Golgi apparatus GTP-binding Hydrolase Membrane Methylation Microtubule Motor protein Nitration Nucleotide-binding Phosphoprotein Reference proteome Synapse | MGNRGMEDLI | MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVNSTTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKIAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVDEYKNFRPD... | clathrin coat assembly involved in endocytosis endocytosis endosome organization G protein-coupled receptor internalization modulation of chemical synaptic transmission positive regulation of synaptic vesicle endocytosis positive regulation of synaptic vesicle recycling protein homooligomerization protein homotetrameri... |
actin cytoskeleton organization cell division endocytosis lipid tube assembly meiotic cell cycle peroxisome fission peroxisome organization protein retention in Golgi apparatus protein targeting to vacuole vacuolar transport | actin cortical patch; cytoplasm; cytosol; fungal-type vacuole membrane; late endosome; membrane; microtubule; mitochondrial outer membrane; mitochondrion; peroxisome | GTP binding GTPase activity microtubule binding | Saccharomyces cerevisiae | Cell cycle Cell division Cytoplasm Cytoskeleton GTP-binding Meiosis Microtubule Motor protein Nucleotide-binding Phosphoprotein Reference proteome | MDEHLISTIN | MDEHLISTINKLQDALAPLGGGSQSPIDLPQITVVGSQSSGKSSVLENIVGRDFLPRGTGIVTRRPLVLQLINRRPKKSEHAKVNQTANELIDLNINDDDKKKDESGKHQNEGQSEDNKEEWGEFLHLPGKKFYNFDEIRKEIVKETDKVTGANSGISSVPINLRIYSPHVLTLTLVDLPGLTKVPVGDQPPDIERQIKDMLLKYISKPNAIILSVNAANTDLANSDGLKLAREVDPEGTRTIGVLTKVDLMDQGTDVIDILAGRVIPLRYGYIPVINRGQKDIEHKKTIREALENERKFFENHPSYSSKAHYCGTPYLA... | actin cytoskeleton organization cell division endocytosis lipid tube assembly meiotic cell cycle peroxisome fission peroxisome organization protein retention in Golgi apparatus protein targeting to vacuole vacuolar transport actin cortical patch; cytoplasm; cytosol; fungal-type vacuole membrane; late endosome; membrane... |
calcium ion-regulated exocytosis of neurotransmitter calcium-dependent activation of synaptic vesicle fusion cell differentiation cellular response to calcium ion chemical synaptic transmission detection of calcium ion fast, calcium ion-dependent exocytosis of neurotransmitter neurotransmitter secretion positive regula... | axon; chromaffin granule membrane; clathrin-coated endocytic vesicle membrane; clathrin-sculpted acetylcholine transport vesicle membrane; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane; clathrin-sculpted glutamate transport vesicle membrane; clathrin-sculpted monoamine transport vesicle membrane;... | calcium ion binding calcium ion sensor activity calcium-dependent phospholipid binding calcium-dependent protein binding calmodulin binding clathrin binding identical protein binding low-density lipoprotein particle receptor binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylserine binding protein hetero... | Homo sapiens | 3D-structure Calcium Cytoplasm Cytoplasmic vesicle Differentiation Disease variant Glycoprotein Lipoprotein Membrane Metal-binding Palmitate Phosphoprotein Reference proteome Repeat Synapse Transmembrane Transmembrane helix | MVSESHHEAL | MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQN... | calcium ion-regulated exocytosis of neurotransmitter calcium-dependent activation of synaptic vesicle fusion cell differentiation cellular response to calcium ion chemical synaptic transmission detection of calcium ion fast, calcium ion-dependent exocytosis of neurotransmitter neurotransmitter secretion positive regula... |
adenosine biosynthetic process adenosine metabolic process ADP catabolic process AMP catabolic process ATP metabolic process calcium ion homeostasis inhibition of non-skeletal tissue mineralization leukocyte cell-cell adhesion negative regulation of inflammatory response positive regulation of lipid biosynthetic proces... | cell surface; external side of plasma membrane; membrane; plasma membrane; synaptic membrane | 5'-deoxynucleotidase activity 5'-nucleotidase activity ferrous iron binding GMP 5'-nucleotidase activity identical protein binding IMP 5'-nucleotidase activity nucleotide binding thymidylate 5'-phosphatase activity XMP 5'-nucleosidase activity zinc ion binding | Rattus norvegicus | Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Metal-binding Nucleotide-binding Reference proteome Signal Zinc | MRPAAATAPK | MRPAAATAPKWLLLALSALLPLWPTAKSWELTIMHTNDVHSRLEQTSDDSTKCLNASLCVGGVARLFTKVQQIRKEEPNVLLLDAGDQYQGTIWFTVYKGLEVAHFMNLLGYDAMALGNHEFDNGVEGLIDPLLRNVKFPILSANIKARGPLAPQISGLYLPYKVLSVGGEVVGIVGYTSKETPFLSNPGTNLVFEDEVTALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHTNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKVEFDDKGNVVTSYGNPILLNSTIREDA... | adenosine biosynthetic process adenosine metabolic process ADP catabolic process AMP catabolic process ATP metabolic process calcium ion homeostasis inhibition of non-skeletal tissue mineralization leukocyte cell-cell adhesion negative regulation of inflammatory response positive regulation of lipid biosynthetic proces... |
adenosine biosynthetic process ADP catabolic process AMP catabolic process ATP metabolic process calcium ion homeostasis DNA metabolic process inhibition of non-skeletal tissue mineralization leukocyte cell-cell adhesion negative regulation of inflammatory response response to ATP response to inorganic substance | cell surface; cytosol; external side of plasma membrane; extracellular exosome; membrane; nucleoplasm; plasma membrane | 5'-deoxynucleotidase activity 5'-nucleotidase activity GMP 5'-nucleotidase activity identical protein binding IMP 5'-nucleotidase activity nucleotide binding thymidylate 5'-phosphatase activity XMP 5'-nucleosidase activity zinc ion binding | Homo sapiens | 3D-structure Alternative splicing Cell membrane Direct protein sequencing Disease variant Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Metal-binding Nucleotide-binding Reference proteome Signal Zinc | MCPRAARAPA | MCPRAARAPATLLLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNSSIPEDPSI... | adenosine biosynthetic process ADP catabolic process AMP catabolic process ATP metabolic process calcium ion homeostasis DNA metabolic process inhibition of non-skeletal tissue mineralization leukocyte cell-cell adhesion negative regulation of inflammatory response response to ATP response to inorganic substance cell s... |
heme A biosynthetic process | mitochondrial membrane; mitochondrion | protoheme IX farnesyltransferase activity | Saccharomyces cerevisiae | Heme biosynthesis Membrane Mitochondrion Reference proteome Transferase Transit peptide Transmembrane Transmembrane helix | MSYFPRTYAH | MSYFPRTYAHLMRNVLAHNKGNIYLQIGTQLHDTQIKIRFNGVRYISRNHGGKQQHINTAPIEFTPNFGYGDRTSNCNKKVESTAMKTLRCTDDISTSSGSEATTDASTQLPFNVKLVDPMVRKSKRPSHAISEGLNMKTLKKKVIMPYLQLTKPRLTILVMLSAICSYALSPYPASVNELLCLTVGTTLCSGSANAINMGREPEFDRQMVRTQARPVVRGDVTPTQAFEFAALIGTLGVSILYFGVNPTVAILGASNIALYGWAYTSMKRKHIINTWLGALVGMVPPLMGWAAASPLSHPGSWCLAGLLFAWQFPHFNT... | heme A biosynthetic process mitochondrial membrane; mitochondrion protoheme IX farnesyltransferase activity Saccharomyces cerevisiae Heme biosynthesis Membrane Mitochondrion Reference proteome Transferase Transit peptide Transmembrane Transmembrane helix MSYFPRTYAH MSYFPRTYAHLMRNVLAHNKGNIYLQIGTQLHDTQIKIRFNGVRYISRNHGGK... |
glycolytic process phosphorylation | cytoplasm; cytosol; pyruvate kinase complex | AMP binding ATP binding identical protein binding kinase activity magnesium ion binding potassium ion binding pyruvate kinase activity | Escherichia coli | 3D-structure Acetylation Allosteric enzyme ATP-binding Direct protein sequencing Glycolysis Kinase Magnesium Metal-binding Nucleotide-binding Potassium Pyruvate Reference proteome Transferase | MSRRLRRTKI | MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGKGEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNKGINKLGGGLSAEALTEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDAKIVAKVERAEAVCSQDAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAE... | glycolytic process phosphorylation cytoplasm; cytosol; pyruvate kinase complex AMP binding ATP binding identical protein binding kinase activity magnesium ion binding potassium ion binding pyruvate kinase activity Escherichia coli 3D-structure Acetylation Allosteric enzyme ATP-binding Direct protein sequencing Glycolys... |
DNA-templated transcription DNA-templated viral transcription | DNA-directed RNA polymerase complex; host cell cytoplasm; virion component | DNA binding DNA-directed 5'-3' RNA polymerase activity zinc ion binding | Vaccinia virus ) | Alternative initiation DNA-directed RNA polymerase Early protein Host cytoplasm Metal-binding Nucleotidyltransferase Reference proteome Transcription Transferase Virion Zinc Zinc-finger | MENVYISSYS | MENVYISSYSSNEQTSMAVTATDIRELLSQYVDDANLEDLIEWAMEKSSKYYIKNIGNTKSNIEETKFESKNNIGIEYSKDSRNKLSYRNKPSIATNLEYKTLCDMIKGTSGTEKEFLRYLLFGIKCIKKGVEYNIDKIKDVSYNDYFNVLDEKYNTPCPNCKSRNTTPMMIQTRAADEPPLVRHACRDCKQHFKPPKFRAFRNLNVTTQSIHENKEITEILPDNNPSPPESPEPASPIDDGLIRATFDRNDEPPEDDE | DNA-templated transcription DNA-templated viral transcription DNA-directed RNA polymerase complex; host cell cytoplasm; virion component DNA binding DNA-directed 5'-3' RNA polymerase activity zinc ion binding Vaccinia virus )Alternative initiation DNA-directed RNA polymerase Early protein Host cytoplasm Metal-binding... |
evasion of host immune response perturbation by virus of host apoptosis suppression by virus of host apoptotic process suppression by virus of host ISG15-protein conjugation suppression by virus of host PKR signaling suppression by virus of host type I interferon production suppression by virus of host type I interfero... | cytoplasm | double-stranded RNA adenosine deaminase activity double-stranded RNA binding protein sequestering activity protein serine/threonine kinase inhibitor activity RNA binding | Vaccinia virus ) | 3D-structure Alternative initiation Direct protein sequencing Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host IRF3 by virus Inhibition of host IRF7 by virus Inhibition of host ISG15 by virus Inhibition of host PKR by v... | MSKIYIDERS | MSKIYIDERSNAEIVCEAIKTIGIEGATAAQLTRQLNMEKREVNKALYDLQRSAMVYSSDDIPPRWFMTTEADKPDADAMADVIIDDVSREKSMREDHKSFDDVIPAKKIIDWKGANPVTVINEYCQITRRDWSFRIESVGPSNSPTFYACVDIDGRVFDKADGKSKRDAKNNAAKLAVDKLLGYVIIRF | evasion of host immune response perturbation by virus of host apoptosis suppression by virus of host apoptotic process suppression by virus of host ISG15-protein conjugation suppression by virus of host PKR signaling suppression by virus of host type I interferon production suppression by virus of host type I interfero... |
amyloid fibril formation antigen processing and presentation of endogenous peptide antigen via MHC class I antigen processing and presentation of exogenous peptide antigen via MHC class II cellular response to iron ion cellular response to nicotine immune response intracellular iron ion homeostasis learning or memory n... | cytosol; extracellular region; Golgi apparatus; HFE-transferrin receptor complex; late endosome membrane; lysosomal membrane; MHC class I peptide loading complex; MHC class I protein complex; MHC class II protein complex | MHC class II protein complex binding peptide antigen binding protein homodimerization activity structural molecule activity | Gallus gallus | 3D-structure Direct protein sequencing Disulfide bond Immunity Immunoglobulin domain MHC I Reference proteome Secreted Signal | MGKAAAVVLV | MGKAAAVVLVTLVALLGLAQADLTPKVQVYSRFPASAGTKNVLNCFAAGFHPPKISITLMKDGVPMEGAQYSDMSFNDDWTFQRLVHADFTPSSGSTYACKVEHETLKEPQVYKWDPEF | amyloid fibril formation antigen processing and presentation of endogenous peptide antigen via MHC class I antigen processing and presentation of exogenous peptide antigen via MHC class II cellular response to iron ion cellular response to nicotine immune response intracellular iron ion homeostasis learning or memory n... |
vitamin D metabolic process | axon; cytoplasm; extracellular space; perinuclear region of cytoplasm | actin binding calcidiol binding vitamin D binding vitamin transmembrane transporter activity | Mus musculus | Actin-binding Direct protein sequencing Disulfide bond Glycoprotein Phosphoprotein Reference proteome Repeat Secreted Signal Transport Vitamin D | MKRVLVLLLA | MKRVLVLLLALAFGHALERGRDYEKDKVCNELAMLGKEDFRSLSLILYSRKFSSSTFEQVNQLVKEVVSLTEECCAEGADPTCYDTRTSELSVKSCESDAPFPVHPGTPECCTKEGLERKLCMAALSHQPQEFPTYVEPTNDEICEAFRRDPKGFADQFLYEYSSNYGQAPLPLLVAYTKNYLSMVGSCCTSANPTVCFVKERLQMKHLSLLTTMSNRVCSQYAAYGKEKSRLSHLIKLAQKVPTANLENVLPLAEDFTEILSRCCESTSEDCMASELPEHTIKICQNLSKKNSKFEECCQENTPMNIFMCTYFMPAAEP... | vitamin D metabolic process axon; cytoplasm; extracellular space; perinuclear region of cytoplasm actin binding calcidiol binding vitamin D binding vitamin transmembrane transporter activity Mus musculus Actin-binding Direct protein sequencing Disulfide bond Glycoprotein Phosphoprotein Reference proteome Repeat Secrete... |
heterochromatin formation nuclear envelope organization nuclear migration nuclear pore localization protein localization to nuclear envelope | lamin filament; nuclear envelope; nuclear lamina; nuclear membrane; nuclear periphery; nucleus | identical protein binding structural constituent of cytoskeleton | Mus musculus | Acetylation Alternative splicing Coiled coil Direct protein sequencing Intermediate filament Isopeptide bond Lipoprotein Methylation Nucleus Phosphoprotein Prenylation Reference proteome Ubl conjugation | MASLPPHAGP | MASLPPHAGPATPLSPTRLSRLQEKEELRELNDRLAHYIDRVRALELENDRLLLRISEKEEVTTREVSGIKTLYESELADARRVLDETARERARLQIEIGKVQAELEEARKSAKKREGELTVAQGRVKDLESLFHRSEAELATALSDKQGLETEVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEELAFSKSVFEEEVRETRRRHERRLVEVDSSRQQEYDFKMAQALEDLRSQHDEQVRLYRVELEQTYQAKLDNAKLLSDQNDKAAHAAREELKEARMRVESLSYQLLGLQKQASAAENHIHELEEAL... | heterochromatin formation nuclear envelope organization nuclear migration nuclear pore localization protein localization to nuclear envelope lamin filament; nuclear envelope; nuclear lamina; nuclear membrane; nuclear periphery; nucleus identical protein binding structural constituent of cytoskeleton Mus musculus Acetyl... |
cellular response to dexamethasone stimulus cellular response to ethanol cellular response to glucose stimulus cellular response to insulin stimulus egg-laying behavior eggshell formation embryo development ending in birth or egg hatching embryonic organ morphogenesis gluconeogenesis glucose catabolic process to lactat... | cytosol; mitochondrial matrix | GTP binding manganese ion binding phosphoenolpyruvate carboxykinase (GTP) activity | Gallus gallus | 3D-structure Decarboxylase Direct protein sequencing Gluconeogenesis GTP-binding Lyase Manganese Metal-binding Mitochondrion Nucleotide-binding Reference proteome Transit peptide | MFWLRGGAQS | MFWLRGGAQSCRGGETEDRMQRGMWGVGLARRRLSTSLSALPAAARDFVEEAVRLCRPREVLLCDGSEEEGKELLRGLQDDGVLHPLPKYDNCWLARTDPRDVARVESKTVLVTPEQSDAVPPPPPSGGPPQLGNWMSPNAFQAAVQERFPGCMAGRPLYVIPFSMGPPTSPLAKLGVQVTDSPYVVLSMRIMTRVGPAVLQRLDDDFVRCLHSVGRPLPLTEPLVSSWPCDRSPVLVAHIPSERRIVSFGSGYGGNSLLGKKCFALRIASRMAQQQGWLAEHMLILGVTSPSGEKRYMAAAFPSACGKTNLAMMTPSLP... | cellular response to dexamethasone stimulus cellular response to ethanol cellular response to glucose stimulus cellular response to insulin stimulus egg-laying behavior eggshell formation embryo development ending in birth or egg hatching embryonic organ morphogenesis gluconeogenesis glucose catabolic process to lactat... |
lipid A biosynthetic process response to antibiotic | cytoplasm; cytosol | identical protein binding N-acyltransferase activity UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity | Escherichia coli | 3D-structure Acyltransferase Antibiotic resistance Direct protein sequencing Lipid A biosynthesis Lipid biosynthesis Lipid metabolism Reference proteome Repeat Transferase | MPSIRLADLA | MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVNPKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAPSAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTIYHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRGALDDTIIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGHMEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALV... | lipid A biosynthetic process response to antibiotic cytoplasm; cytosol identical protein binding N-acyltransferase activity UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity Escherichia coli 3D-structure Acyltransferase Antibiotic resistance Direct protein sequencing Lipid A biosynthesis Lipid biosy... |
meiotic DNA double-strand break formation reciprocal meiotic recombination | condensed nuclear chromosome; nucleus | identical protein binding | Saccharomyces cerevisiae | Chromosome DNA recombination Meiosis Nucleus Phosphoprotein Reference proteome | MVARGRTDEI | MVARGRTDEISTDVSEANSEHSLMITETSSPFRSIFSHSGKVANAGALEESDKQILEWAGKLELESMELRENSDKLIKVLNENSKTLCKSLNKFNQLLEQDAATNGNVKTLIKDLASQIENQLDKVSTAMLSKGDEKKTKSDSSYRQVLVEEISRYNSKITRHVTNKQHETEKSMRCTQEMLFNVGSQLEDVHKVLLSLSKDMHSLQTRQTALEMAFREKADHAYDRPDVSLNGTTLLHDMDEAHDKQRKKSVPPPRMMVTRSMKRRRSSSPTLSTSQNHNSEDNDDASHRLKRAARTIIPWEELRPDTLESEL | meiotic DNA double-strand break formation reciprocal meiotic recombination condensed nuclear chromosome; nucleus identical protein binding Saccharomyces cerevisiae Chromosome DNA recombination Meiosis Nucleus Phosphoprotein Reference proteome MVARGRTDEI MVARGRTDEISTDVSEANSEHSLMITETSSPFRSIFSHSGKVANAGALEESDKQILEWAGKLELE... |
angiogenesis animal organ morphogenesis cartilage condensation cell differentiation fibroblast growth factor receptor signaling pathway myoblast differentiation positive regulation of cell division positive regulation of cell population proliferation positive regulation of gene expression positive regulation of protein... | cytoplasm; extracellular space; sarcolemma | fibroblast growth factor receptor binding growth factor activity | Mus musculus | Angiogenesis Developmental protein Differentiation Disulfide bond Glycoprotein Growth factor Mitogen Proto-oncogene Reference proteome Secreted Signal | MALGQRLFIT | MALGQRLFITMSRGAGRVQGTLQALVFLGVLVGMVVPSPAGARANGTLLDSRGWGTLLSRSRAGLAGEISGVNWESGYLVGIKRQRRLYCNVGIGFHLQVPPDGRISGTHEENPYSLLEISTVERGVVSLFGVKSALFIAMNSKGRLYTTPSFHDECKFRETLLPNNYNAYESDLYRGTYIALSKYGRVKRGSKVSPIMTVTHFLPRI | angiogenesis animal organ morphogenesis cartilage condensation cell differentiation fibroblast growth factor receptor signaling pathway myoblast differentiation positive regulation of cell division positive regulation of cell population proliferation positive regulation of gene expression positive regulation of protein... |
enkephalin processing insulin processing islet amyloid polypeptide processing nervous system development peptide hormone processing protein autoprocessing protein processing proteolysis | dendrite; endoplasmic reticulum lumen; extracellular space; intracellular membrane-bounded organelle; membrane; neuron projection; neuronal cell body; nucleoplasm; perikaryon; secretory granule; secretory granule lumen; transport vesicle | endopeptidase activity serine-type endopeptidase activity | Mus musculus | Cleavage on pair of basic residues Cytoplasmic vesicle Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Secreted Serine protease Signal Zymogen | MEGGCGSQWK | MEGGCGSQWKAAGFLFCVMVFASAERPVFTNHFLVELHKDGEEEARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKRQLERDPRIKMALQQEGFDRKKRGYRDINEIDINMNDPLFTKQWYLFNTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLAYNYNADASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAASNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDG... | enkephalin processing insulin processing islet amyloid polypeptide processing nervous system development peptide hormone processing protein autoprocessing protein processing proteolysis dendrite; endoplasmic reticulum lumen; extracellular space; intracellular membrane-bounded organelle; membrane; neuron projection; neu... |
deoxyribonucleotide biosynthetic process DNA replication | cytoplasm; mitochondrion; ribonucleoside-diphosphate reductase complex | ATP binding ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | Saccharomyces cerevisiae | Allosteric enzyme ATP-binding Cytoplasm Deoxyribonucleotide synthesis Disulfide bond Isopeptide bond Nucleotide-binding Oxidoreductase Phosphoprotein Reference proteome Ubl conjugation | MYVIKRDGRK | MYVIKRDGRKEPVQFDKITSRITRLSYGLDPNRIDAVKVTQRIISGVYSGVTTVELDNLAAETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVIEDLHDWINPATGKHAPMISDEIYNIVMENKDTLNSAIVYDRDFQYTYFGFKTLERSYLLRLNGEVAERPQHLVMRVALGIHGSDIESVLKTYNLMSLRYFTHASPTLFNAGTPHPQMSSCFLIAMKDDSIEGIYDTLKECAMISKTAGGVGLHINNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALFLEPWHADIFDFVDIRKTHGK... | deoxyribonucleotide biosynthetic process DNA replication cytoplasm; mitochondrion; ribonucleoside-diphosphate reductase complex ATP binding ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Saccharomyces cerevisiae Allosteric enzyme ATP-binding Cytoplasm Deoxyribonucleotide synthesis Dis... |
angiogenesis polyamine biosynthetic process putrescine catabolic process spermidine acetylation | cytosol | diamine N-acetyltransferase activity identical protein binding N-acetyltransferase activity spermidine binding | Homo sapiens | 3D-structure Acyltransferase Cytoplasm Direct protein sequencing Reference proteome Transferase | MAKFVIRPAT | MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKNLSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE | angiogenesis polyamine biosynthetic process putrescine catabolic process spermidine acetylation cytosol diamine N-acetyltransferase activity identical protein binding N-acetyltransferase activity spermidine binding Homo sapiens 3D-structure Acyltransferase Cytoplasm Direct protein sequencing Reference proteome Transfer... |
ameloblast differentiation BMP signaling pathway cell differentiation cellular response to growth factor stimulus female gonad development gamete generation hair follicle morphogenesis hematopoietic progenitor cell differentiation keratinocyte proliferation negative regulation of activin receptor signaling pathway nega... | cytoplasm; extracellular space; nucleus | activin binding activin receptor antagonist activity heparan sulfate proteoglycan binding | Rattus norvegicus | 3D-structure Disulfide bond Glycoprotein Reference proteome Repeat Secreted Signal | MVCARHQPGG | MVCARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGRLSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGKCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPEPSSSEQSLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCGGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSIS... | ameloblast differentiation BMP signaling pathway cell differentiation cellular response to growth factor stimulus female gonad development gamete generation hair follicle morphogenesis hematopoietic progenitor cell differentiation keratinocyte proliferation negative regulation of activin receptor signaling pathway nega... |
B cell lineage commitment cell development chromatin remodeling gastrulation gene expression immunoglobulin V(D)J recombination lymphocyte differentiation natural killer cell differentiation negative regulation of transcription by RNA polymerase II Peyer's patch development positive regulation of B cell proliferation p... | chromatin; cytoplasm; cytosol; euchromatin; nucleosome; nucleus; protein-containing complex; RNA polymerase II transcription regulator complex; transcription regulator complex | bHLH transcription factor binding chromatin binding cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcr... | Rattus norvegicus | Alternative splicing DNA-binding Isopeptide bond Methylation Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MMNQSQRMAP | MMNQSQRMAPVGSDKELSDLLDFSMMFPLPVANGKGRPASLAGTQFAGSGLEDRPSSESWGNSEQNSSSFDPSRAYSEGAHFSDSHSSLPPSTFLGAGLGGKGSERNAYATFGRDTSVGTLSQAGFLPGELGLSSPGPLSPSGVKSSSQYYTSFPSNPRRRAADGGLDTQPKKVRKVPPGLPSSVYPSSSGDNYSRDATAYPSAKTPSSAYPSPFYVADGSLHPSAELWSPPGQVGFGPMLGDGSAPLPLAPGSSSVSSGAFGGLQQQDRMGYQLHGSEVNGTLPAVSSFSAAPGTYSGTSGHTPPVSGADSLLGTRGTT... | B cell lineage commitment cell development chromatin remodeling gastrulation gene expression immunoglobulin V(D)J recombination lymphocyte differentiation natural killer cell differentiation negative regulation of transcription by RNA polymerase II Peyer's patch development positive regulation of B cell proliferation p... |
heterochromatin formation silent mating-type cassette heterochromatin formation | chromatin silencing complex; chromosome, centromeric region | chromatin binding | Saccharomyces cerevisiae | 3D-structure Centromere Chromosome Nucleus Reference proteome Repressor Transcription Transcription regulation | MLQINSRLAV | MLQINSRLAVIDGWLVDTVKRKPINFRSPEVRLLLPNDDDYKKLSQQNLVDWTRLKKDSNSVLVGVKSMELFKHIKLVLREFFLLEDGRIILKRIRSKLRYKVVKKLTCKCCRLYLPKWGTVYIHPMLKDKEKPLAGVCEFSLDVNPDREYPLIEINVSHQYIIIEGFLLYLNERRLYRWNDNNLRSQVGLTKWAHLRKTYNPVSLDILYSLNSNFYFVKDDLLFQLLGKRVFVKFCKVMENGKCGKAPLWYRVKRTTTAKATHIAYAISNSTAPDSFKSKNNDYRFIVREKPIVENTISNLDYSDIKKQQFTEAEVVKR... | heterochromatin formation silent mating-type cassette heterochromatin formation chromatin silencing complex; chromosome, centromeric region chromatin binding Saccharomyces cerevisiae 3D-structure Centromere Chromosome Nucleus Reference proteome Repressor Transcription Transcription regulation MLQINSRLAV MLQINSRLAVIDGW... |
cellular response to UV-A collagen catabolic process extracellular matrix organization positive regulation of protein-containing complex assembly proteolysis | extracellular matrix; extracellular space | metalloendopeptidase activity peptidase activity zinc ion binding | Sus scrofa | 3D-structure Autocatalytic cleavage Calcium Collagen degradation Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Hydrolase Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Repeat Secreted Signal Zinc Zymogen | MFSLLLLLLL | MFSLLLLLLLLCNTGSHGFPAATSETQEQDVEIVQKYLKNYYNLNSDGVPVEKKRNSGLVVEKLKQMQQFFGLKVTGKPDAETLNVMKQPRCGVPDVAEFVLTPGNPRWENTHLTYRIENYTPDLSREDVDRAIEKAFQLWSNVSPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTKNFRDYNLYRVAAHELGHSLGLSHSTDIGALMYPNYIYTGDVQLSQDDIDGIQAIYGPSENPVQPSGPQTPQVCDSKLTFDAITTLRGELMFFKDRFYMRTNSFYPEVELNFISVF... | cellular response to UV-A collagen catabolic process extracellular matrix organization positive regulation of protein-containing complex assembly proteolysis extracellular matrix; extracellular space metalloendopeptidase activity peptidase activity zinc ion binding Sus scrofa 3D-structure Autocatalytic cleavage Calcium... |
ribosome biogenesis | cytosol | 3'-5' RNA helicase activity ADP binding ATP binding ATP hydrolysis activity DNA/RNA helicase activity RNA helicase activity rRNA binding | Escherichia coli | 3D-structure ATP-binding Cytoplasm Helicase Hydrolase Nucleotide-binding Reference proteome Ribosome biogenesis RNA-binding | MTAFSTLNVL | MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTKILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLDMGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQQFYETSSKGKIPLLQRLLSLHQPSSCVVFCNTKKDCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAW... | ribosome biogenesis cytosol 3'-5' RNA helicase activity ADP binding ATP binding ATP hydrolysis activity DNA/RNA helicase activity RNA helicase activity rRNA binding Escherichia coli 3D-structure ATP-binding Cytoplasm Helicase Hydrolase Nucleotide-binding Reference proteome Ribosome biogenesis RNA-binding MTAFSTLNVL MTA... |
negative stranded viral RNA replication suppression by virus of host gene expression suppression by virus of host PKR signaling suppression by virus of host transcription suppression by virus of host transcription initiation from RNA polymerase II promoter suppression by virus of host type I interferon production suppr... | host cell cytoplasm; host cell nucleus | protein serine/threonine kinase inhibitor activity | Rift valley fever virus | 3D-structure Eukaryotic host gene expression shutoff by virus Eukaryotic host transcription shutoff by virus Host cytoplasm Host gene expression shutoff by virus Host nucleus Host-virus interaction Inhibition of eukaryotic host transcription initiation by virus Inhibition of host innate immune response by virus Inhibit... | MDYFPVISVD | MDYFPVISVDLQSGRRVVSVEYFRGDGPPRIPYSMVGPCCVFLMHHRPSHEVRLRFSDFYNVGEFPYRVGLGDFASNVAPPPAKPFQRLIDLIGHMTLSDFTRFPNLKEAISWPLGEPSLAFFDLSSTRVHRNDDIRRDQIATLAMRSCKITNDLEDSFVGLHRMIATEAILRGIDLCLLPGFDLMYEVAHVQCVRLLQAAKEDISNAVVPNSALIVLMEESLMLRSSLPSMMGRNNWIPVIPPIPDVEMESEEESDDDGFVEVD | negative stranded viral RNA replication suppression by virus of host gene expression suppression by virus of host PKR signaling suppression by virus of host transcription suppression by virus of host transcription initiation from RNA polymerase II promoter suppression by virus of host type I interferon production suppr... |
apoptotic process DNA catabolic process neutrophil activation involved in immune response regulation of acute inflammatory response regulation of neutrophil mediated cytotoxicity | extracellular region; nuclear envelope; nucleus; zymogen granule | actin binding deoxyribonuclease I activity DNA binding DNA nuclease activity | Rattus norvegicus | Actin-binding Apoptosis Calcium Cytoplasmic vesicle Disulfide bond Endonuclease Glycoprotein Hydrolase Nuclease Nucleus Reference proteome Secreted Signal | MRYTGLMGIL | MRYTGLMGILLTLVNLLQLAATLRIAAFNIRTFGDTKMSNATLSSYIVKILSRYDIAVVQEVRDTHLVAVGKLLDELNRDIPDNYRYIISEPLGRKSYKEQYLFVYRPSQVSVLDSYHYDDGCEPCGNDTFSREPAIVKFFSPYTEVREFAIVPLHSAPTEAVSEIDALYDVYLDVRQKWGLEDIMFMGDFNAGCSYVTSSQWSSIRLRTSPIFQWLIPDSADTTATSTHCAYDRIVVAGALLQAAVVPSSAVPFDFQAEYRLTNQMAEAISDHYPVEVTLRKT | apoptotic process DNA catabolic process neutrophil activation involved in immune response regulation of acute inflammatory response regulation of neutrophil mediated cytotoxicity extracellular region; nuclear envelope; nucleus; zymogen granule actin binding deoxyribonuclease I activity DNA binding DNA nuclease activity... |
activation of GTPase activity angiogenesis cell surface receptor signaling pathway ephrin receptor signaling pathway negative regulation of cell migration negative regulation of protein kinase activity peptidyl-tyrosine phosphorylation positive regulation of angiogenesis positive regulation of cell migration positive r... | plasma membrane; receptor complex | ATP binding fibronectin binding protein kinase activity protein kinase binding transmembrane receptor protein tyrosine kinase activity transmembrane-ephrin receptor activity | Homo sapiens | 3D-structure Alternative splicing Angiogenesis ATP-binding Cell adhesion Cell membrane Glycoprotein Kinase Membrane Nucleotide-binding Phosphoprotein Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase Ubl conjugation | MERRWPLGLG | MERRWPLGLGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNGTPLYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPAGLVEVAGTCLPHARASPRPSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAESEGATICTCESGHYRA... | activation of GTPase activity angiogenesis cell surface receptor signaling pathway ephrin receptor signaling pathway negative regulation of cell migration negative regulation of protein kinase activity peptidyl-tyrosine phosphorylation positive regulation of angiogenesis positive regulation of cell migration positive r... |
G protein-coupled receptor signaling pathway learning or memory motor behavior phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of behavioral fear response positive regulation of respiratory gaseous exchange psychomotor behavior regulation of cell population proliferation resp... | plasma membrane | bombesin receptor activity G protein-coupled peptide receptor activity G protein-coupled receptor activity neuropeptide binding neuropeptide receptor activity | Mus musculus | Cell membrane Direct protein sequencing Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MAPNNCSHLN | MAPNNCSHLNLDVDPFLSCNDTFNQSLSPPKMDNWFHPGFIYVIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFSDLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLAIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNP... | G protein-coupled receptor signaling pathway learning or memory motor behavior phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of behavioral fear response positive regulation of respiratory gaseous exchange psychomotor behavior regulation of cell population proliferation resp... |
activation of phospholipase C activity amyloid-beta clearance astrocyte activation cellular defense response chemotaxis cognition complement component C5a signaling pathway complement receptor mediated signaling pathway defense response to Gram-positive bacterium immune response inflammatory response microglial cell ac... | apical part of cell; basolateral plasma membrane; plasma membrane; secretory granule membrane | complement component C5a receptor activity G protein-coupled receptor activity | Homo sapiens | 3D-structure Cell membrane Chemotaxis Cytoplasmic vesicle Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Sulfation Transducer Transmembrane Transmembrane helix | MDSFNYTTPD | MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQGRLRKSLPSLLR... | activation of phospholipase C activity amyloid-beta clearance astrocyte activation cellular defense response chemotaxis cognition complement component C5a signaling pathway complement receptor mediated signaling pathway defense response to Gram-positive bacterium immune response inflammatory response microglial cell ac... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway cellular response to lipopolysaccharide G protein-coupled receptor signaling pathway inflammatory response negative regulation of cell migration involved in sprouting angiogenesis positive regulation of angiogenesis positive regulation of blood c... | acrosomal vesicle; nuclear speck; plasma membrane | guanyl-nucleotide exchange factor activity thromboxane A2 receptor activity | Homo sapiens | Alternative splicing Cell membrane Direct protein sequencing Disease variant Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MWPNGSSLGP | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQ... | adenylate cyclase-activating G protein-coupled receptor signaling pathway cellular response to lipopolysaccharide G protein-coupled receptor signaling pathway inflammatory response negative regulation of cell migration involved in sprouting angiogenesis positive regulation of angiogenesis positive regulation of blood c... |
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