Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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cell redox homeostasis deoxyribonucleotide biosynthetic process endoplasmic reticulum to Golgi vesicle-mediated transport glutathione metabolic process protein deglutathionylation protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum sulfate assimilation vacuole fusion, non-autophagic ... | cytoplasm; cytosol; fungal-type vacuole; Golgi membrane; membrane fusion priming complex; nucleus | disulfide oxidoreductase activity protein-disulfide reductase activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Deoxyribonucleotide synthesis Direct protein sequencing Disulfide bond Electron transport Golgi apparatus Isopeptide bond Membrane Nucleus Phosphoprotein Protein transport Redox-active center Reference proteome Transport Ubl conjugation | MVTQLKSASE | MVTQLKSASEYDSALASGDKLVVVDFFATWCGPCKMIAPMIEKFAEQYSDAAFYKLDVDEVSDVAQKAEVSSMPTLIFYKGGKEVTRVVGANPAAIKQAIASNV | cell redox homeostasis deoxyribonucleotide biosynthetic process endoplasmic reticulum to Golgi vesicle-mediated transport glutathione metabolic process protein deglutathionylation protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum sulfate assimilation vacuole fusion, non-autophagic ... |
endoplasmic reticulum to Golgi vesicle-mediated transport intracellular protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum vesicle fusion vesicle fusion with Golgi apparatus | COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum membrane; Golgi membrane; membrane; SNARE complex | SNAP receptor activity | Saccharomyces cerevisiae | 3D-structure Coiled coil Endoplasmic reticulum ER-Golgi transport Golgi apparatus Membrane Protein transport Reference proteome Transmembrane Transmembrane helix Transport | MSSRFAGGNA | MSSRFAGGNAYQRDTGRTQLFGPADGSNSLDDNVSSALGSTDKLDYSQSTLASLESQSEEQMGAMGQRIKALKSLSLKMGDEIRGSNQTIDQLGDTFHNTSVKLKRTFGNMMEMARRSGISIKTWLIIFFMVGVLFFWVWIT | endoplasmic reticulum to Golgi vesicle-mediated transport intracellular protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum vesicle fusion vesicle fusion with Golgi apparatus COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum membrane; Golgi membrane; membrane; SNARE c... |
cell differentiation muscle cell fate determination muscle organ development negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Drosophila melanogaster | Developmental protein DNA-binding Homeobox Nucleus Reference proteome Repeat | MVMLQSPAQK | MVMLQSPAQKASDSASAQNTAVGGLMSPNSNPDSPKSNTSPDVASADSVVSGTGGGSTPPAAKIPKFIISANGAAVAGKQEQELRYSLERLKQMSSESGSLLSRLSPLQEDSQDKEKPNHNNNNSLTNHNANSNTRRSQSPPASVGSVSFSSPAQQRKLLELNAVRHLARPEPLQHPHAALLQQHPHLLQNPQFLAAAQQHMHHHQHQHHQHPAHPHSHQHPHPHPHPHPHPHPSAVFHLRAPSSSSTAPPSPATSPLSPPTSPAMHSDQQMSPPIAPPQNPPHSSQPPQQQQVAAPSDMDLERIKLVAAVAARTTQASS... | cell differentiation muscle cell fate determination muscle organ development negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific ... |
brain development cell differentiation glial cell development negative regulation of gene expression negative regulation of transcription by RNA polymerase II neuroblast development neuroblast fate determination positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Drosophila melanogaster | 3D-structure Developmental protein Differentiation DNA-binding Homeobox Neurogenesis Nucleus Reference proteome Transcription Transcription regulation | MTTSASLERT | MTTSASLERTPSKRDRDRERDNSSGLGSAGSLPASPQSAITVSPSSPATPKRPLRTSTPSLERKREREDREDREDRKERQERHERDRDHERFAAVFSTASTTVPTNTSSSSGLAPEQLRIPTGAAAFSGFPGLHSMSSLMLPSSAAVAAAAAAPFLPWSPILLPPWNHALLPAAFYPAALRNALPGLFDAKVPSSQRSGFHISDILNLEGSELKNAAAAAAAAAHHGSDLSHHSASESTSGHRGQGSHTSPSALSPTPAGVSADEHHNGSGTGGGAGEADHHSTTEHHAPPSHPQQQHPHHQQHHHPHLLLPQQHHQQAV... | brain development cell differentiation glial cell development negative regulation of gene expression negative regulation of transcription by RNA polymerase II neuroblast development neuroblast fate determination positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II n... |
cell differentiation mesoderm development mesodermal cell fate commitment positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II visceral muscle development | nucleus | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Drosophila melanogaster | Developmental protein DNA-binding Homeobox Nucleus Reference proteome | MLNMESAGVS | MLNMESAGVSAAMAGLSKSLTTPFSINDILTRSNPETRRMSSVDSEPEPEKLKPSSDRERSISKSPPLCCRDLGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAADYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAALLGASKRVPVQVLVREDGSTTYAHMAAPGAGHGLDPALINIYRHQLQLAYGGLPLPQMQMPFPYFYPQHKVPQPIPPPT... | cell differentiation mesoderm development mesodermal cell fate commitment positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II visceral muscle development nucleus DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis... |
adult walking behavior anterior head segmentation anterior region determination brain development brain segmentation central nervous system development compound eye morphogenesis compound eye photoreceptor development embryonic development via the syncytial blastoderm negative regulation of transcription by RNA polymer... | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Drosophila melanogaster | Developmental protein DNA-binding Homeobox Nucleus Reference proteome Repeat Transcription Transcription regulation | MAAGFLKSGD | MAAGFLKSGDLGPHPHSYGGPHPHHSVPHGPLPPGMPMPSLGPFGLPHGLEAVGFSQGMWGVNTRKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQLQQQQQSNSLSSSKNASGGGSGNSCSSSSANSRSNSNNNGSSSNNNTQSSGGNNSNKSSQKQGNSQSSQQGGGSSGGNNSNNNSAAAAASAAAAVAAAQSIKTHHSSFLSAAAAAASGGTNQSANNNSNNNNQGNSTPNSSSSGGGGGSQAGGHLSAAAAAAALNVTAAHQNSSPLLPTPATSVSPVSIVCKKEH... | adult walking behavior anterior head segmentation anterior region determination brain development brain segmentation central nervous system development compound eye morphogenesis compound eye photoreceptor development embryonic development via the syncytial blastoderm negative regulation of transcription by RNA polymer... |
apoptotic process determination of dorsal/ventral asymmetry dorsal/ventral pattern formation hemocyte proliferation innate immune response larval somatic muscle development positive regulation of antifungal peptide production response to fungus Toll signaling pathway | cytoplasm; cytoplasmic side of plasma membrane; cytosol; nucleus; plasma membrane | protein domain specific binding protein tyrosine kinase binding | Drosophila melanogaster | 3D-structure Cell membrane Cytoplasm Developmental protein Membrane Reference proteome Repeat Transducer | MAYGWNGCGM | MAYGWNGCGMGVQVNGSNGAIGLSSKYSRNTELRRVEDNDIYRLAKILDENSCWRKLMSIIPKGMDVQACSGAGCLNFPAEIKKGFKYTAQDVFQIDEAANRLPPDQSKSQMMIDEWKTSGKLNERPTVGVLLQLLVQAELFSAADFVALDFLNESTPARPVDGPGALISLELLEEEMEVDNEGLSLKYQSSTATLGADAQGSVGLNLDNFEKDIVRRDKSVPQPSGNTPPIAPPRRQQRSTTNSNFATLTGTGTTSTTIPNVPNLTILNPSEQIQEPVLQPRPMNIPDLSILISNSGDLRATVSDNPSNRTSSTDPPNI... | apoptotic process determination of dorsal/ventral asymmetry dorsal/ventral pattern formation hemocyte proliferation innate immune response larval somatic muscle development positive regulation of antifungal peptide production response to fungus Toll signaling pathway cytoplasm; cytoplasmic side of plasma membrane; cyto... |
defense response to bacterium defense response to fungus negative regulation of DNA-templated transcription positive regulation of DNA binding positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to heat | chromatin; nucleus; polytene chromosome | DNA binding DNA-binding transcription factor activity identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Drosophila melanogaster | 3D-structure Activator Direct protein sequencing DNA-binding Nucleus Phosphoprotein Reference proteome Stress response Transcription Transcription regulation | MSRSRSSAKA | MSRSRSSAKAVQFKHESEEEEEDEEEQLPSRRMHSYGDAAAIGSGVPAFLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFIRQLNMYGFHKITSIDNGGLRFDRDEIEFSHPFFKRNSPFLLDQIKRKISNNKNGDDKGVLKPEAMSKILTDVKVMRGRQDNLDSRFSAMKQENEVLWREIASLRQKHAKQQQIVNKLIQFLITIVQPSRNMSGVKRHVQLMINNTPEIDRARTTSETESESGGGPVIHELREELLDEVMNPSPAGYTAASHYDQESVSPPAVERPRSNMSISSHNVDYS... | defense response to bacterium defense response to fungus negative regulation of DNA-templated transcription positive regulation of DNA binding positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to heat ch... |
axon guidance eye morphogenesis germ-band extension negative regulation of DNA-templated transcription neuroblast fate determination periodic partitioning by pair rule gene positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II segment polarity determination sex det... | nucleus | ATP binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Drosophila melanogaster | Developmental protein Nucleus Pair-rule protein Reference proteome Segmentation polarity protein Transcription Transcription regulation | MHLPAGPTMV | MHLPAGPTMVANNTQVLAAAAAAAAAAAAAVAQGPGPQQSSNATTASAIAINPAQSLANTSTHSASSTGSSTPDLSTNNTSSSSNATTSPQNSAKMPSSMTDMFASLHEMLQEYHGELAQTGSPSILCSALPNHWRSNKSLPGAFKVIALDDVPDGTLVSIKCGNDENYCGELRNCTTTMKNQVAKFNDLRFVGRSGRGKSFTLTITIATYPVQIASYSKAIKVTVDGPREPRSKQSYGYPHPGAFNPFMLNPAWLDAAYMTYGYADYFRHQAAAQAAQVHHPALAKSSASSVSPNPNPSVATSSSSAVQPSEYPHPAAA... | axon guidance eye morphogenesis germ-band extension negative regulation of DNA-templated transcription neuroblast fate determination periodic partitioning by pair rule gene positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II segment polarity determination sex det... |
germ-line stem-cell niche homeostasis glucose homeostasis lipid homeostasis R7 cell fate commitment R8 cell-mediated photoreceptor organization response to glucose sevenless signaling pathway visual perception | plasma membrane; rhabdomere microvillus membrane | adenylate cyclase inhibiting G protein-coupled glutamate receptor activity receptor ligand activity sevenless binding | Drosophila melanogaster | Cell membrane G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Sensory transduction Signal Transducer Transmembrane Transmembrane helix Vision | MKVMDALQSG | MKVMDALQSGRRKPLPVALLCILVTVFCVLECHGADLTSPTKKSAPLRITKPQPTSQQAKPISITTRAPTTVASTTDDEVSSSVDGQLAPLISSTTEGPSSGTTASLVPEICLNGLQLTVNSADEGTVIRKQEEFVKILEGDVVLSVLTKDPDSALFVINRVNQANLIMADFEIGIRAISIDNASLAENLLIQEVQFLQQCTTYSMGIFVDWELYKQLESVIKDLEYNIWPIPGTRAHLFPKVAHLLHQMPWGEKIASVEIATETLEMYNEFMEAARQEHMCLMHFKSDDNVYIMFGNKLASHFKENGTLFSVPTDRTDD... | germ-line stem-cell niche homeostasis glucose homeostasis lipid homeostasis R7 cell fate commitment R8 cell-mediated photoreceptor organization response to glucose sevenless signaling pathway visual perception plasma membrane; rhabdomere microvillus membrane adenylate cyclase inhibiting G protein-coupled glutamate rece... |
cell differentiation determination of muscle attachment site larval somatic muscle development muscle organ development positive regulation of myoblast differentiation regulation of transcription by RNA polymerase II | cytoplasm; nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Drosophila melanogaster | Developmental protein Differentiation DNA-binding Myogenesis Nucleus Reference proteome Transcription Transcription regulation | MTKYNSGSSE | MTKYNSGSSEMPAAQTIKQEYHNGYGQPTHPGYGFSAYSQQNPIAHPGQNPHQTLQNFFSRFNAVGDASAGNGGAASISANGSGSSCNYSHANHHPAELDKPLGMNMTPSPIYTTDYDDENSSLSSEEHVLAPLVCSSAQSSRPCLTWACKACKKKSVTVDRRKAATMRERRRLRKVNEAFEILKRRTSSNPNQRLPKVEILRNAIEYIESLEDLLQESSTTRDGDNLAPSLSGKSCQSDYLSSYAGAYLEDKLSFYNKHMEKYGQFTDFDGNANGSSLDCLNLIVQSINKSTTSPIQNKATPSASDTQSPPSSGATAPT... | cell differentiation determination of muscle attachment site larval somatic muscle development muscle organ development positive regulation of myoblast differentiation regulation of transcription by RNA polymerase II cytoplasm; nucleus DNA-binding transcription factor activity, RNA polymerase II-specific protein dimeri... |
defense response to Gram-negative bacterium determination of adult lifespan insulin catabolic process negative regulation of developmental growth negative regulation of growth negative regulation of insulin receptor signaling pathway peptide catabolic process positive regulation of innate immune response proteolysis pr... | cytoplasm; cytosol; mitochondrion; peroxisome; plasma membrane | metal ion binding metalloendopeptidase activity metallopeptidase activity | Drosophila melanogaster | Direct protein sequencing Hydrolase Metal-binding Metalloprotease Protease Reference proteome Zinc | MTIAESSQKS | MTIAESSQKSATRKPDSMEPILRLNNIEKSLQDTRDYRGLQLENGLKVLLISDPNTDVSAAALSVQVGHMSDPTNLPGLAHFCEHMLFLGTEKYPHENGYTTYLSQSGGSSNAATYPLMTKYHFHVAPDKLDGALDRFAQFFIAPLFTPSATEREINAVNSEHEKNLPSDLWRIKQVNRHLAKPDHAYSKFGSGNKTTLSEIPKSKNIDVRDELLKFHKQWYSANIMCLAVIGKESLDELEGMVLEKFSEIENKNVKVPGWPRHPYAEERYGQKVKIVPIKDIRSLTISFTTDDLTQFYKSGPDNYLTHLIGHEGKGSIL... | defense response to Gram-negative bacterium determination of adult lifespan insulin catabolic process negative regulation of developmental growth negative regulation of growth negative regulation of insulin receptor signaling pathway peptide catabolic process positive regulation of innate immune response proteolysis pr... |
cellular response to dexamethasone stimulus cholesterol metabolic process detection of UV erythrocyte differentiation generation of precursor metabolites and energy heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process multicellular organismal-level iron ion homeo... | mitochondrial inner membrane; mitochondrial matrix; mitochondrion | 2 iron, 2 sulfur cluster binding ferrochelatase activity ferrous iron binding heme binding identical protein binding iron-responsive element binding protein homodimerization activity | Homo sapiens | 2Fe-2S 3D-structure Acetylation Alternative splicing Disease variant Heme biosynthesis Iron Iron-sulfur Lyase Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Porphyrin biosynthesis Reference proteome Transit peptide | MRSLGANMAA | MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQVQPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIK... | cellular response to dexamethasone stimulus cholesterol metabolic process detection of UV erythrocyte differentiation generation of precursor metabolites and energy heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process multicellular organismal-level iron ion homeo... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway bone mineralization calcium ion homeostasis chondrocyte differentiation endochondral ossification endoderm development lung alveolus development lung epithelial cell differentiation magnesium ion homeostasis mammary gland bud elongation negative ... | cytosol; extracellular space; Golgi apparatus; nucleoplasm; nucleus | hormone activity peptide hormone receptor binding | Mus musculus | Calcium Cleavage on pair of basic residues Cytoplasm Hormone Nucleus Reference proteome Secreted Signal | MLRRLVQQWS | MLRRLVQQWSVLVFLLSYSVPSRGRSVEGLGRRLKRAVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTAEIRATSEVSPNSKPAPNTKNHPVRFGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRREQEKKKRRTRSAWPSTAASGLLEDPLPHTSRTSLEPSLRTH | adenylate cyclase-activating G protein-coupled receptor signaling pathway bone mineralization calcium ion homeostasis chondrocyte differentiation endochondral ossification endoderm development lung alveolus development lung epithelial cell differentiation magnesium ion homeostasis mammary gland bud elongation negative ... |
actin cytoskeleton organization asexual reproduction CTP biosynthetic process dGTP biosynthetic process from dGDP G protein-coupled receptor signaling pathway GTP biosynthetic process negative regulation of exocytosis negative regulation of phagocytosis negative regulation of pinocytosis nucleoside triphosphate biosynt... | cytoplasm; cytoskeleton; phagocytic vesicle; plasma membrane; ribosome; secretory granule | ATP binding metal ion binding nucleoside diphosphate kinase activity | Dictyostelium discoideum | 3D-structure ATP-binding Cytoplasm Kinase Magnesium Metal-binding Nucleotide metabolism Nucleotide-binding Phosphoprotein Reference proteome Transferase | MSTNKVNKER | MSTNKVNKERTFLAVKPDGVARGLVGEIIARYEKKGFVLVGLKQLVPTKDLAESHYAEHKERPFFGGLVSFITSGPVVAMVFEGKGVVASARLMIGVTNPLASAPGSIRGDFGVDVGRNIIHGSDSVESANREIALWFKPEELLTEVKPNPNLYE | actin cytoskeleton organization asexual reproduction CTP biosynthetic process dGTP biosynthetic process from dGDP G protein-coupled receptor signaling pathway GTP biosynthetic process negative regulation of exocytosis negative regulation of phagocytosis negative regulation of pinocytosis nucleoside triphosphate biosynt... |
blood coagulation proteolysis | endoplasmic reticulum lumen; extracellular exosome; extracellular space; Golgi lumen | calcium ion binding serine-type endopeptidase activity | Homo sapiens | 3D-structure Alternative splicing Blood coagulation Calcium Cleavage on pair of basic residues Direct protein sequencing Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Hemostasis Hydroxylation Reference proteome Repeat Secreted Serine protease homolog Signal | MAGCVPLLQG | MAGCVPLLQGLVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGTDLGNSLTTRPVT... | blood coagulation proteolysis endoplasmic reticulum lumen; extracellular exosome; extracellular space; Golgi lumen calcium ion binding serine-type endopeptidase activity Homo sapiens 3D-structure Alternative splicing Blood coagulation Calcium Cleavage on pair of basic residues Direct protein sequencing Disulfide bond E... |
basolateral protein secretion endosome to melanosome transport Golgi to lysosome transport Golgi to vacuole transport intracellular protein transport melanosome assembly platelet dense granule organization positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytot... | AP-1 adaptor complex; clathrin-coated pit; clathrin-coated vesicle; cytosol; early endosome; Golgi apparatus; intracellular membrane-bounded organelle; lysosomal membrane; perinuclear region of cytoplasm; recycling endosome; trans-Golgi network; trans-Golgi network membrane | clathrin adaptor activity GTP-dependent protein binding kinesin binding small GTPase binding | Mus musculus | 3D-structure Coated pit Cytoplasm Cytoplasmic vesicle Direct protein sequencing Golgi apparatus Membrane Protein transport Reference proteome Transport | MPAPIRLREL | MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNN... | basolateral protein secretion endosome to melanosome transport Golgi to lysosome transport Golgi to vacuole transport intracellular protein transport melanosome assembly platelet dense granule organization positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytot... |
cellular response to lipopolysaccharide collagen catabolic process endodermal cell differentiation extracellular matrix disassembly extracellular matrix organization positive regulation of microglial cell activation positive regulation of neuroinflammatory response positive regulation of tumor necrosis factor productio... | collagen-containing extracellular matrix; extracellular region; extracellular space; specific granule lumen; tertiary granule lumen | endopeptidase activity metalloendopeptidase activity peptidase activity serine-type endopeptidase activity tumor necrosis factor binding zinc ion binding | Homo sapiens | 3D-structure Calcium Collagen degradation Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Hydrolase Metal-binding Metalloprotease Protease Reference proteome Repeat Secreted Signal Zinc Zymogen | MFSLKTLPFL | MFSLKTLPFLLLLHVQISKAFPVSSKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIVEKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEILFFKDRYFWRRHPQLQRVEMNFISL... | cellular response to lipopolysaccharide collagen catabolic process endodermal cell differentiation extracellular matrix disassembly extracellular matrix organization positive regulation of microglial cell activation positive regulation of neuroinflammatory response positive regulation of tumor necrosis factor productio... |
heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process liver development porphyrin-containing compound biosynthetic process porphyrin-containing compound metabolic process protoporphyrinogen IX biosynthetic process response to xenobiotic stimulus tetrapyrrole biosy... | axon; cytoplasm; cytosol; perinuclear region of cytoplasm | amine binding carboxylic acid binding hydroxymethylbilane synthase activity uroporphyrinogen-III synthase activity | Mus musculus | Acetylation Alternative splicing Heme biosynthesis Phosphoprotein Porphyrin biosynthesis Reference proteome Transferase | MSGNGGAATT | MSGNGGAATTAEENGSKMRVIRVGTRKSQLARIQTDTVVAMLKALYPGIQFEIIAMSTTGDKILDTALSKIGEKSLFTKELENALEKNEVDLVVHSLKDVPTILPPGFTIGAICKRENPCDAVVFHPKFIGKTLETLPEKSAVGTSSLRRVAQLQRKFPHLEFKSIRGNLNTRLRKLDELQEFSAIVLAVAGLQRMGWQNRVGQILHPEECMYAVGQGALAVEVRAKDQDILDLVSVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTVMKDGQLYLTGGVWSLDGSDSMQETMQATIQVPVQQEDGPEDDPQLVGITA... | heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process liver development porphyrin-containing compound biosynthetic process porphyrin-containing compound metabolic process protoporphyrinogen IX biosynthetic process response to xenobiotic stimulus tetrapyrrole biosy... |
nitrogen fixation | nitrogenase complex | 4 iron, 4 sulfur cluster binding ATP binding carbonyl sulfide nitrogenase activity metal ion binding nitrogenase activity | Rhodospirillum rubrum | 4Fe-4S ADP-ribosylation ATP-binding Direct protein sequencing Iron Iron-sulfur Metal-binding Nitrogen fixation Nucleotide-binding Oxidoreductase | MSALRQIAFY | MSALRQIAFYGKGGIGKSTTSQNTLAALVEMGQRILIVGCDPKADSTRLILNTKLQDTVLHLAAEAGSVEDLDVADVVKIGYKGIKCTESGGPEPGVGCAGRGVITAINFLEENGAYDDLDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMALYAANNIAKGILKYAHTGGVRLGGLICNERQTDKEVELAEALAGRLGCRLIHFVPRDNGVQHAELRRQTVIQYAPDSKQAGEYRTLATKIHNNSGQGVVPTPITMEDLEEMLMEFGIMKSDEEALAELEAKESAAAN | nitrogen fixation nitrogenase complex 4 iron, 4 sulfur cluster binding ATP binding carbonyl sulfide nitrogenase activity metal ion binding nitrogenase activity Rhodospirillum rubrum4Fe-4S ADP-ribosylation ATP-binding Direct protein sequencing Iron Iron-sulfur Metal-binding Nitrogen fixation Nucleotide-binding Oxidoredu... |
neuropeptide signaling pathway | extracellular region | hormone activity | Pelophylax ridibundus | Amidation Cleavage on pair of basic residues Endorphin Glycoprotein Hormone Pyrrolidone carboxylic acid Secreted Signal | MLQPVWSCIL | MLQPVWSCILALLGVFIFHVGEVRSQCWESNKCTDLSSEDGILECIKACKMDLSAESPVFPGNGHMQPLSENIRKYVMSHFRWNKFGRRNSTSNDNNNGGYKREDIANYPILNLLTGSDNQNTQQGIMEDEAVDRQDSKRSYSMEHFRWGKPVGKKRRPIKVFPTDAEEESSEIFPLELRRELSLEFDYPDTNSEEDLDDGELLDGPVKKDRKYKMHHFRWEGPPKDKRYGGFMTPERSQTPLMTLFKNAIIKNAHKKGQ | neuropeptide signaling pathway extracellular region hormone activity Pelophylax ridibundus Amidation Cleavage on pair of basic residues Endorphin Glycoprotein Hormone Pyrrolidone carboxylic acid Secreted Signal MLQPVWSCIL MLQPVWSCILALLGVFIFHVGEVRSQCWESNKCTDLSSEDGILECIKACKMDLSAESPVFPGNGHMQPLSENIRKYVMSHFRWNKFGRRNSTSNDNN... |
chemical synaptic transmission chloride transmembrane transport gamma-aminobutyric acid signaling pathway synaptic transmission, GABAergic | axon; chloride channel complex; dendrite; GABA-A receptor complex; GABA-ergic synapse; glutamatergic synapse; neuron projection; neuronal cell body; postsynaptic membrane; synapse | chloride channel activity GABA-A receptor activity neurotransmitter receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Mus musculus | Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Postsynaptic cell membrane Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MDVLGWLLLP | MDVLGWLLLPLLLLCTQPHHGARAMNDIGDYVGSNLEISWLPNLDGLMEGYARNFRPGIGGAPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYNHTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYPLDEQECMLDLESYGYSSEDIVYYWSENQEQIHGLDRLQLAQFTITSYRFTTELMNFKSAGQFPRLSLHFQLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVF... | chemical synaptic transmission chloride transmembrane transport gamma-aminobutyric acid signaling pathway synaptic transmission, GABAergic axon; chloride channel complex; dendrite; GABA-A receptor complex; GABA-ergic synapse; glutamatergic synapse; neuron projection; neuronal cell body; postsynaptic membrane; synapse c... |
embryonic forelimb morphogenesis fatty acid transport positive regulation of collateral sprouting retinoic acid metabolic process | cytoplasm; cytosol; endoplasmic reticulum; nucleoplasm; nucleus | cyclin binding fatty acid binding retinal binding retinoic acid binding retinol binding | Mus musculus | Cytoplasm Endoplasmic reticulum Isopeptide bond Nucleus Reference proteome Retinol-binding Transport Ubl conjugation Vitamin A | MPNFSGNWKI | MPNFSGNWKIIRSENFEEMLKALGVNMMMRKIAVAAASKPAVEIKQENDTFYIKTSTTVRTTEINFKIGEEFEEQTVDGRPCKSLVKWESGNKMVCEQRLLKGEGPKTSWSRELTNDGELILTMTADDVVCTRVYVRE | embryonic forelimb morphogenesis fatty acid transport positive regulation of collateral sprouting retinoic acid metabolic process cytoplasm; cytosol; endoplasmic reticulum; nucleoplasm; nucleus cyclin binding fatty acid binding retinal binding retinoic acid binding retinol binding Mus musculus Cytoplasm Endoplasmic ret... |
base-excision repair | mitochondrion; nucleus | 3'-5'-DNA exonuclease activity 3'-tyrosyl-DNA phosphodiesterase activity DNA binding DNA-(apurinic or apyrimidinic site) endonuclease activity double-stranded DNA 3'-5' DNA exonuclease activity phosphoric diester hydrolase activity zinc ion binding | Saccharomyces cerevisiae | Direct protein sequencing DNA damage DNA repair Hydrolase Metal-binding Nucleus Phosphoprotein Reference proteome Zinc | MPSTPSFVRS | MPSTPSFVRSAVSKYKFGAHMSGAGGISNSVTNAFNTGCNSFAMFLKSPRKWVSPQYTQEEIDKFKKNCATYNYNPLTDVLPHGQYFINLANPDREKAEKSYESFMDDLNRCEQLGIGLYNLHPGSTLKGDHQLQLKQLASYLNKAIKETKFVKIVLENMAGTGNLVGSSLVDLKEVIGMIEDKSRIGVCIDTCHTFAAGYDISTTETFNNFWKEFNDVIGFKYLSAVHLNDSKAPLGANRDLHERLGQGYLGIDVFRMIAHSEYLQGIPIVLETPYENDEGYGNEIKLMEWLESKSESELLEDKEYKEKNDTLQKLGAK... | base-excision repair mitochondrion; nucleus 3'-5'-DNA exonuclease activity 3'-tyrosyl-DNA phosphodiesterase activity DNA binding DNA-(apurinic or apyrimidinic site) endonuclease activity double-stranded DNA 3'-5' DNA exonuclease activity phosphoric diester hydrolase activity zinc ion binding Saccharomyces cerevisiae D... |
cell adhesion cellular response to heat cellular response to osmotic stress cellular response to oxidative stress plasma membrane organization | cytoplasm; cytosol; endosome; nucleus; plasma membrane | lipid binding protein folding chaperone | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing Phosphoprotein Reference proteome Stress response | MSDAGRKGFG | MSDAGRKGFGEKASEALKPDSQKSYAEQGKEYITDKADKVAGKVQPEDNKGVFQGVHDSAEKGKDNAEGQGESLADQARDYMGAAKSKLNDAVEYVSGRVHGEEDPTKK | cell adhesion cellular response to heat cellular response to osmotic stress cellular response to oxidative stress plasma membrane organization cytoplasm; cytosol; endosome; nucleus; plasma membrane lipid binding protein folding chaperone Saccharomyces cerevisiae 3D-structure Direct protein sequencing Phosphoprotein Re... |
defense response to bacterium defense response to fungus defense response to other organism heat acclimation negative regulation of seed germination response to heat response to virus stomatal closure | apoplast; chloroplast; cytoplasm; cytosol; cytosolic ribosome; Golgi apparatus; nucleolus; nucleus; plant-type cell wall; plant-type vacuole; plasma membrane; plasmodesma | ATP binding ATP-dependent protein folding chaperone mRNA binding protease binding | Arabidopsis thaliana | Acetylation Alternative splicing ATP-binding Chaperone Cytoplasm Nucleotide-binding Nucleus Plant defense Reference proteome Stress response Transcription Transcription regulation | MSGKGEGPAI | MSGKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPVNTVFDAKRLIGRRFSDSSVQSDMKLWPFKIQAGPADKPMIYVEYKGEEKEFAAEEISSMVLIKMREIAEAYLGVTIKNAVVTVPAYFNDSQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKATSVGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRMVNHFVQEFKRKSKKDITGNPRALRRLRTSCERAKRTLSSTAQTTIEIDSLYEGIDFYSTITRARFEELNMDLFRKCM... | defense response to bacterium defense response to fungus defense response to other organism heat acclimation negative regulation of seed germination response to heat response to virus stomatal closure apoplast; chloroplast; cytoplasm; cytosol; cytosolic ribosome; Golgi apparatus; nucleolus; nucleus; plant-type cell wal... |
response to bacterium response to heat response to virus | cytosol; Golgi apparatus; nucleus; plant-type cell wall; plasma membrane | ATP binding ATP-dependent protein folding chaperone | Arabidopsis thaliana | ATP-binding Chaperone Cytoplasm Nucleotide-binding Nucleus Reference proteome Stress response Transcription Transcription regulation | MAGKGEGPAI | MAGKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPVNTVFDAKRLIGRRFSDASVQSDRQLWPFTIISGTAEKPMIVVEYKGEEKQFAAEEISSMVLIKMREIAEAFLGTTVKNAVVTVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKKATSVGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRMVNHFVQEFKRKNKQDITGQPRALRRLRTACERAKRTLSSTAQTTIEIDSLYGGADFYSPITRARFEEMNMDLFRKCM... | response to bacterium response to heat response to virus cytosol; Golgi apparatus; nucleus; plant-type cell wall; plasma membrane ATP binding ATP-dependent protein folding chaperone Arabidopsis thaliana ATP-binding Chaperone Cytoplasm Nucleotide-binding Nucleus Reference proteome Stress response Transcription Transcrip... |
viral RNA genome replication | host cell endoplasmic reticulum membrane; membrane | nucleotide binding RNA binding RNA-dependent RNA polymerase activity | Red clover necrotic mosaic virus | Host endoplasmic reticulum Host membrane Membrane Nucleotide-binding Nucleotidyltransferase Reference proteome Ribosomal frameshifting RNA-directed RNA polymerase Suppressor of RNA silencing Transferase Viral RNA replication | MGFINLSLFD | MGFINLSLFDVDKLMVWVSKFNPGKILSAICNLGIDCWNRFRKWFFGLNFDAHMWAVDAFIPLMPHYTEQMERVVDDFCSETPESKLEDCLELDTSVNEFFDEEVYKKDEEGVMKLQRSAARKHIKRVRPGMMQAAIKAVETRIRNRHTIFGDDMGKVDEAAVRATASDICGEFKINEHHTNALVYAAAYLAMTPDQRSIDSVKLAYNPKSQARRTLVSAIRENKAVAGFKSLEDFLGGPLSFPVEDAPYPILGIPEIRVAEKRASRVMKSKRVVGLPAVSAGLKVCVHQTSLHNMIVSLERRVFRVKNSAGELVVPPKP... | viral RNA genome replication host cell endoplasmic reticulum membrane; membrane nucleotide binding RNA binding RNA-dependent RNA polymerase activity Red clover necrotic mosaic virus Host endoplasmic reticulum Host membrane Membrane Nucleotide-binding Nucleotidyltransferase Reference proteome Ribosomal frameshifting RNA... |
muscle organ development positive regulation of mesodermal cell fate specification positive regulation of muscle cell differentiation positive regulation of myoblast differentiation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II striated muscle cell differenti... | nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Caenorhabditis elegans | Alternative splicing Developmental protein Differentiation DNA-binding Myogenesis Nucleus Reference proteome Transcription Transcription regulation | MNTETSTQSA | MNTETSTQSAPSDTYDTSIYYNSSPRVTANDITTLTSFAAPAPQVLDYANTQYDIYRNQPAYYLPSYAPTAPTTFYSDFANFNVTRSQDFASVPAVANSSDVKPIIIKQEKSTPNATELIIQSRVDSQHEDTTTSTAGGAGVGGPRRTKFVLSVDRRKAATMRERRRLRKVNEAFEVVKQRTCPNPNQRLPKVEILRSAIDYINNLERMLQQAGKMTKIMEQNQHLQMTQQINGAPPHDYVTSSHFASSSYNPENMFDDDDLTDSDDDRDHHKLGNAVDLRRRNSLDRLSRIVASIPNEEAMTDEQLLQPANDVIDGEKK... | muscle organ development positive regulation of mesodermal cell fate specification positive regulation of muscle cell differentiation positive regulation of myoblast differentiation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II striated muscle cell differenti... |
associative learning epidermal growth factor receptor signaling pathway muscle organ development nematode larval development oogenesis positive regulation of receptor localization to synapse positive regulation of vulval development Ras protein signal transduction regulation of cell fate specification regulation of cel... | cell cortex; plasma membrane | GDP binding GTP binding GTPase activity phospholipase binding protein serine/threonine kinase binding | Caenorhabditis elegans | Cell membrane GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome | MTEYKLVVVG | MTEYKLVVVGDGGVGKSALTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNEAKSFENVANYREQIRRVKDSDDVPMVLVGNKCDLSSRSVDFRTVSETAKGYGIPNVDTSAKTRMGVDEAFYTLVREIRKHRERHDNNKPQKKKKCQIM | associative learning epidermal growth factor receptor signaling pathway muscle organ development nematode larval development oogenesis positive regulation of receptor localization to synapse positive regulation of vulval development Ras protein signal transduction regulation of cell fate specification regulation of cel... |
cell growth mode switching, monopolar to bipolar establishment or maintenance of actin cytoskeleton polarity establishment or maintenance of cell polarity regulating cell shape intracellular signal transduction mitotic cytokinesis, division site positioning phosphorylation plasma membrane organization positive regulati... | cell cortex of cell tip; cell division site; cell tip; medial cortex; microtubule cytoskeleton; mitotic actomyosin contractile ring; new growing cell tip; non-growing cell tip; old cell tip after activation of bipolar cell growth | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Schizosaccharomyces pombe | ATP-binding Cytoplasm Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MEYRTNNVPV | MEYRTNNVPVGNETKSAALNALPKIKISDSPNRHHNLVDAFMQSPSYSTQPKSAVEPLGLSFSPGYISPSSQSPHHGPVRSPSSRKPLPASPSRTRDHSLRVPVSGHSYSADEKPRERRKVIGNYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKNKEIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNLYRRQSRLRTFCGSLYFAAPELLNAQPYIGP... | cell growth mode switching, monopolar to bipolar establishment or maintenance of actin cytoskeleton polarity establishment or maintenance of cell polarity regulating cell shape intracellular signal transduction mitotic cytokinesis, division site positioning phosphorylation plasma membrane organization positive regulati... |
plasmid partitioning | extracellular region | DNA binding endonuclease activity exonuclease activity | Escherichia coli | DNA-binding Endonuclease Exonuclease Hydrolase Nuclease Plasmid Plasmid partition Secreted Signal | MKRRSYAMLR | MKRRSYAMLRAAAALAVLVVASPAWAELRGEVVRIIDGDTIDVLVDKQPVRVRLVDIDAPEKRQAFGERARQALAGMVFRRHVLVDEKDTDRYGRTLGTVWVNMELASRPPQPRNVNAAMVHQGMAWAYRFHGRAADPEMLRLEQEARGKRVGLWSDPHAVEPWKWRRESNNRRDEG | plasmid partitioning extracellular region DNA binding endonuclease activity exonuclease activity Escherichia coliDNA-binding Endonuclease Exonuclease Hydrolase Nuclease Plasmid Plasmid partition Secreted Signal MKRRSYAMLR MKRRSYAMLRAAAALAVLVVASPAWAELRGEVVRIIDGDTIDVLVDKQPVRVRLVDIDAPEKRQAFGERARQALAGMVFRRHVLVDEKDTDRYGRTLG... |
tRNA folding tRNA methylation | cytosol | rRNA binding tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent tRNA binding | Escherichia coli | 3D-structure Direct protein sequencing Methyltransferase Reference proteome S-adenosyl-L-methionine Transferase tRNA processing | MTPEHLPTEQ | MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHYRMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLRHKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTKIELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELYCGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRIL... | tRNA folding tRNA methylation cytosol rRNA binding tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent tRNA binding Escherichia coli 3D-structure Direct protein sequencing Methyltransferase Reference proteome S-adenosyl-L-methionine Transferase tRNA processing MTPEHLPTEQ MTPEHLPTEQYEAQLAEKV... |
transport of virus in host, cell to cell | host cell plasmodesma; T=3 icosahedral viral capsid | DNA binding GTP binding RNA binding structural molecule activity | Bean-pod mottle virus | 3D-structure Alternative initiation Capsid protein DNA-binding GTP-binding Host cell junction Nucleotide-binding RNA-binding Suppressor of RNA silencing T=3 icosahedral capsid protein Transport Viral movement protein Virion | MFASFIFSGD | MFASFIFSGDNKLTEKTIFNCGDLDILVVYYTIATQFRKFLPHYIRWHLYTLLIYILPSFLTTEIKYKRNLSNIHISGLFYDNRFKFWTKHDKNLALTEEEKMEVIRNRGIPADVLAKRAHEFEKHVAHESLKDQIPAVDKLYSTKVNKFAKIMNLRQSVVGDLKLLTDGKLYEGKHIPVSNISAGENHVVQIPLMAQEEILSSSASDFKTAMVSKSSKPQATAMHVGAIEIIIDSFASPDCNIVGAMLLVDTYHTNPENAVRSIFVAPFRGGRPIRVVTFPNTIVQIEPDMNSRFQLLSTTTNGDFVQGKDLAMVKVNV... | transport of virus in host, cell to cell host cell plasmodesma; T=3 icosahedral viral capsid DNA binding GTP binding RNA binding structural molecule activity Bean-pod mottle virus 3D-structure Alternative initiation Capsid protein DNA-binding GTP-binding Host cell junction Nucleotide-binding RNA-binding Suppressor of ... |
axon midline choice point recognition courtship behavior female analia development female sex differentiation female somatic sex determination genital disc development imaginal disc-derived female genitalia development imaginal disc-derived male genitalia development male analia development male courtship behavior male... | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding ... | Drosophila melanogaster | 3D-structure Alternative splicing Differentiation DNA-binding Metal-binding Nucleus Reference proteome Sexual differentiation Transcription Transcription regulation Zinc | MVSEENWNSD | MVSEENWNSDTMSDSDMIDSKNDVCGGASSSSGSSISPRTPPNCARCRNHGLKITLKGHKRYCKFRYCTCEKCRLTADRQRVMALQTALRRAQAQDEQRALHMHEVPPANPAATTLLSHHHHVAAPAHVHAHHVHAHHAHGGHHSHHGHVLHHQQAAAAAAAAPSAPASHLGGSSTAASSIHGHAHAHHVHMAAAAAASVAQHQHQSHPHSHHHHHQNHHQHPHQQPATQTALRSPPHSDHGGSVGPATSSSGGGAPSSSNAAAATSSNGSSGGGGGGGGGSSGGGAGGGRSSGTSVITSADHHMTTVPTPAQSLEGSCD... | axon midline choice point recognition courtship behavior female analia development female sex differentiation female somatic sex determination genital disc development imaginal disc-derived female genitalia development imaginal disc-derived male genitalia development male analia development male courtship behavior male... |
base-excision repair DNA repair nucleotide-excision repair nucleotide-excision repair involved in interstrand cross-link repair nucleotide-excision repair, DNA damage recognition protein localization to nucleus response to auditory stimulus UV protection UV-damage excision repair | intercellular bridge; nucleoplasm; nucleotide-excision repair factor 1 complex; nucleus | damaged DNA binding metal ion binding protein domain specific binding protein homodimerization activity sequence-specific double-stranded DNA binding | Homo sapiens | 3D-structure Acetylation Disease variant DNA damage DNA repair DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Ubl conjugation Xeroderma pigmentosum Zinc Zinc-finger | MAAADGALPE | MAAADGALPEAAALEQPAELPASVRASIERKRQRALMLRQARLAARPYSATAAAATGGMANVKAAPKIIDTGGGFILEEEEEEEQKIGKVVHQPGPVMEFDYVICEECGKEFMDSYLMNHFDLPTCDNCRDADDKHKLITKTEAKQEYLLKDCDLEKREPPLKFIVKKNPHHSQWGDMKLYLKLQIVKRSLEVWGSQEALEEAKEVRQENREKMKQKKFDKKVKELRRAVRSSVWKRETIVHQHEYGPEENLEDDMYRKTCTMCGHELTYEKM | base-excision repair DNA repair nucleotide-excision repair nucleotide-excision repair involved in interstrand cross-link repair nucleotide-excision repair, DNA damage recognition protein localization to nucleus response to auditory stimulus UV protection UV-damage excision repair intercellular bridge; nucleoplasm; nucl... |
arachidonic acid secretion lipid catabolic process phospholipid metabolic process | extracellular region | calcium ion binding phospholipase A2 activity toxin activity | Pseudonaja textilis | Calcium Direct protein sequencing Disulfide bond Hydrolase Lipid degradation Lipid metabolism Metal-binding Neurotoxin Presynaptic neurotoxin Reference proteome Secreted Signal Toxin | MHPAHLLVLL | MHPAHLLVLLGVCVSLLGASDIPPLPLNLVQFSYLIRCANKYKRPGWHYANYGCYCGSGGRGTPVDDVDRCCQAHDKCYEDAEKLGCYPKWTTYYYYCGANGPYCKTRTKCQRFVCNCDVVAADCFASYPYNRRYWFYSNKKRCR | arachidonic acid secretion lipid catabolic process phospholipid metabolic process extracellular region calcium ion binding phospholipase A2 activity toxin activity Pseudonaja textilis Calcium Direct protein sequencing Disulfide bond Hydrolase Lipid degradation Lipid metabolism Metal-binding Neurotoxin Presynaptic neuro... |
immune response immunoglobulin mediated immune response | extracellular region; immunoglobulin complex; plasma membrane | antigen binding | Homo sapiens | 3D-structure Adaptive immunity Cell membrane Direct protein sequencing Disulfide bond Immunity Immunoglobulin Immunoglobulin domain Membrane Pyrrolidone carboxylic acid Reference proteome Secreted Signal | MDWTWRILFL | MDWTWRILFLVAAATGAHSQVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYAQKFQGWVTMTRDTSISTAYMELSRLRSDDTAVYYCAR | immune response immunoglobulin mediated immune response extracellular region; immunoglobulin complex; plasma membrane antigen binding Homo sapiens 3D-structure Adaptive immunity Cell membrane Direct protein sequencing Disulfide bond Immunity Immunoglobulin Immunoglobulin domain Membrane Pyrrolidone carboxylic acid Refe... |
bone mineralization bone morphogenesis cellular response to fluid shear stress collagen catabolic process embryonic hindlimb morphogenesis endochondral ossification estrous cycle extracellular matrix disassembly extracellular matrix organization growth plate cartilage development heart development luteolysis ossificati... | extracellular matrix; extracellular region; extracellular space; intercellular canaliculus | calcium ion binding calcium-dependent protein binding collagen binding endopeptidase activity fibronectin binding low-density lipoprotein particle receptor binding metalloendopeptidase activity peptidase activity serine-type endopeptidase activity zinc ion binding | Rattus norvegicus | Calcium Collagen degradation Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Hydrolase Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Repeat Secreted Signal Zinc Zymogen | ATFFLLSWTH | ATFFLLSWTHCWSLPLPYGDDDDDDLSEEDLEFAEHYLKSYYHPVTLAGILKKSTVTSTVDRLREMQSFFGLDVTGKLDDPTLDIMRKPRCGVPDVGVYNVFPRTLKWSQTNLTYRIVNYTPDISHSEVEKAFRKAFKVWSDVTPLNFTRIHDGTADIMISFGTKEHGDFYPFDGPSGLLAHAFPPGPNLGGDAHFDDDETWTSSSKGYNLFIVAAHELGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPEKCDPALSLDAITSLRGETMIFKDRFFWRLHPQQVEPELFLTKS... | bone mineralization bone morphogenesis cellular response to fluid shear stress collagen catabolic process embryonic hindlimb morphogenesis endochondral ossification estrous cycle extracellular matrix disassembly extracellular matrix organization growth plate cartilage development heart development luteolysis ossificati... |
AMP metabolic process GMP salvage IMP biosynthetic process IMP salvage | cytosol | AMP deaminase activity identical protein binding metal ion binding | Homo sapiens | Alternative splicing Disease variant Hydrolase Metal-binding Nucleotide metabolism Phosphoprotein Reference proteome Zinc | MPLFKLPAEE | MPLFKLPAEEKQIDDAMRNFAEKVFASEVKDEGGRQEISPFDVDEICPISHHEMQAHIFHLETLSTSTEARRKKRFQGRKTVNLSIPLSETSSTKLSHIDEYISSSPTYQTVPDFQRVQITGDYASGVTVEDFEIVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEAWVANESFYPVFTPPVKKGEDPFRTDNLPENLGYHLKMKDGVVYVYPNEAAVSKDEPKPLPYPNLDTFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIK... | AMP metabolic process GMP salvage IMP biosynthetic process IMP salvage cytosol AMP deaminase activity identical protein binding metal ion binding Homo sapiens Alternative splicing Disease variant Hydrolase Metal-binding Nucleotide metabolism Phosphoprotein Reference proteome Zinc MPLFKLPAEE MPLFKLPAEEKQIDDAMRNFAEKVFASE... |
cell division G1/S transition of mitotic cell cycle phosphorylation regulation of G2/M transition of mitotic cell cycle regulation of gene expression regulation of meiotic cell cycle response to organic substance signal transduction | cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus | ATP binding cyclin binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity | Zea mays | ATP-binding Cell cycle Cell division Kinase Mitosis Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MEQYEKVEKI | MEQYEKVEKIGEGTYGVVYKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLKEMNHGNIVRLHDVVHSEKRIYLVFEYLDLDLKKFMDSCPEFAKNPTLIKSYLYQILHGVAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGARQYSTPVDVWSVGCIFAEMVNQKPLFPGDSEIDELFKIFRILGTPNEQSWPGVSCLPDFKTAFPRWQAQDLATVVPNLDPAGLDLLSKMLRYEPSKRITARQALEHEYFKDLEVVQ | cell division G1/S transition of mitotic cell cycle phosphorylation regulation of G2/M transition of mitotic cell cycle regulation of gene expression regulation of meiotic cell cycle response to organic substance signal transduction cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus ATP binding cycl... |
deadenylation-dependent decapping of nuclear-transcribed mRNA deadenylation-independent decapping of nuclear-transcribed mRNA follicle cell of egg chamber development habituation messenger ribonucleoprotein complex assembly miRNA-mediated gene silencing by inhibition of translation miRNA-mediated post-transcriptional g... | cytoplasm; cytoplasmic ribonucleoprotein granule; cytoplasmic stress granule; endoplasmic reticulum; messenger ribonucleoprotein complex; neuronal cell body; neuronal ribonucleoprotein granule; P granule; P-body; postsynapse; sensory dendrite | ATP binding ATP hydrolysis activity mRNA binding mRNA regulatory element binding translation repressor activity RNA binding RNA helicase activity | Drosophila melanogaster | 3D-structure Alternative splicing ATP-binding Cell projection Cytoplasm Endoplasmic reticulum Helicase Hydrolase Methylation Nucleotide-binding Phosphoprotein Reference proteome Repressor RNA-binding Translation regulation | MMTEKLNSGH | MMTEKLNSGHTNLTSKGIINDLQIAGNTSDDMGWKSKLKLPPKDNRFKTTDVTDTRGNEFEEFCLKRELLMGIFEKGWERPSPIQEAAIPIALSGKDVLARAKNGTGKTGAYCIPVLEQIDPTKDYIQALVMVPTRELALQTSQICIELAKHLDIRVMVTTGGTILKDDILRIYQKVQLIIATPGRILDLMDKKVADMSHCRILVLDEADKLLSLDFQGMLDHVILKLPKDPQILLFSATFPLTVKNFMEKHLREPYEINLMEELTLKGVTQYYAFVQERQKVHCLNTLFSKLQINQSIIFCNSTQRVELLAKKITELGY... | deadenylation-dependent decapping of nuclear-transcribed mRNA deadenylation-independent decapping of nuclear-transcribed mRNA follicle cell of egg chamber development habituation messenger ribonucleoprotein complex assembly miRNA-mediated gene silencing by inhibition of translation miRNA-mediated post-transcriptional g... |
cellular response to cholesterol cellular response to low-density lipoprotein particle stimulus cholesterol biosynthetic process cholesterol ester hydrolysis involved in cholesterol transport cholesterol homeostasis cholesterol metabolic process epithelial cell differentiation lipid catabolic process medium-chain fatty... | cytoplasm; cytosol; endoplasmic reticulum; endoplasmic reticulum lumen; lipid droplet | carboxylesterase activity carboxylic ester hydrolase activity methylumbelliferyl-acetate deacetylase activity sterol esterase activity | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Lipid droplet Lipid metabolism Phosphoprotein Reference proteome Serine esterase Signal | MWLRAFILAT | MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLG... | cellular response to cholesterol cellular response to low-density lipoprotein particle stimulus cholesterol biosynthetic process cholesterol ester hydrolysis involved in cholesterol transport cholesterol homeostasis cholesterol metabolic process epithelial cell differentiation lipid catabolic process medium-chain fatty... |
blood coagulation, fibrin clot formation embryo implantation extracellular matrix organization negative regulation of cell adhesion negative regulation of cell motility negative regulation of ERK1 and ERK2 cascade negative regulation of protein phosphorylation negative regulation of stem cell proliferation negative reg... | basement membrane; collagen-containing extracellular matrix; elastic fiber; extracellular exosome; extracellular matrix; extracellular region; extracellular space | calcium ion binding extracellular matrix structural constituent fibrinogen binding fibronectin binding identical protein binding integrin binding peptidase activator activity protein-containing complex binding | Homo sapiens | Alternative splicing Calcium Chromosomal rearrangement Direct protein sequencing Disulfide bond EGF-like domain Extracellular matrix Glycoprotein Host-virus interaction Reference proteome Repeat Secreted Signal | MERAAPSRRV | MERAAPSRRVPLPLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFQACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCP... | blood coagulation, fibrin clot formation embryo implantation extracellular matrix organization negative regulation of cell adhesion negative regulation of cell motility negative regulation of ERK1 and ERK2 cascade negative regulation of protein phosphorylation negative regulation of stem cell proliferation negative reg... |
adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen negative regulation of T cell proliferation peptide antigen assembly with MHC class II protein complex positive regulation... | external side of plasma membrane; late endosome membrane; lysosomal membrane; lysosome; MHC class II protein complex; plasma membrane | MHC class II protein complex binding peptide antigen binding protein-containing complex binding | Mus musculus | Adaptive immunity Disulfide bond Glycoprotein Immunity Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix | RSRALILGVL | RSRALILGVLALTTMLSLCGGEDDIEADHVAFYGISVYQSPGDIGQYTFEFDGDELFYVDLDKKETVWMLPEFGQLTSFDPQGGLQEIATGKYNLEILIKDSNFTPAANEAPQATVFPKSPVLLGQPNTLICFVDNIFPPVINITWLRNSKSVTDGVYETSFLVNRDHSFHKLSYLTFIPSDDDIYDCKVEHWGLEEPVLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTIFIIQGLRSGGTSRHPGPL | adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen negative regulation of T cell proliferation peptide antigen assembly with MHC class II protein complex positive regulation... |
homologous chromosome pairing at meiosis meiotic DNA double-strand break formation meiotic DNA double-strand break processing reciprocal meiotic recombination sporulation resulting in formation of a cellular spore synaptonemal complex assembly | condensed nuclear chromosome; nuclear chromosome; nucleoplasm | ATP binding chromatin binding DNA binding DNA end binding DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity metal ion binding | Saccharomyces cerevisiae | Chromosome Direct protein sequencing DNA-binding Isomerase Magnesium Meiosis Metal-binding Nucleus Reference proteome Sporulation Topoisomerase | MALEGLRKKY | MALEGLRKKYKTRQELVKALTPKRRSIHLNSNGHSNGTPCSNADVLAHIKHFLSLAANSLEQHQQPISIVFQNKKKKGDTSSPDIHTTLDFPLNGPHLCTHQFKLKRCAILLNLLKVVMEKLPLGKNTTVRDIFYSNVELFQRQANVVQWLDVIRFNFKLSPRKSLNIIPAQKGLVYSPFPIDIYDNILTCENEPKMQKQTIFPGKPCLIPFFQDDAVIKLGTTSMCNIVIVEKEAVFTKLVNNYHKLSTNTMLITGKGFPDFLTRLFLKKLEQYCSKLISDCSIFTDADPYGISIALNYTHSNERNAYICTMANYKGIR... | homologous chromosome pairing at meiosis meiotic DNA double-strand break formation meiotic DNA double-strand break processing reciprocal meiotic recombination sporulation resulting in formation of a cellular spore synaptonemal complex assembly condensed nuclear chromosome; nuclear chromosome; nucleoplasm ATP binding ch... |
blastocyst formation cytokine precursor processing dibasic protein processing negative regulation of low-density lipoprotein particle receptor catabolic process negative regulation of transforming growth factor beta1 production nerve growth factor production peptide biosynthetic process peptide hormone processing posit... | cell surface; early endosome; endoplasmic reticulum; endoplasmic reticulum lumen; endoplasmic reticulum membrane; endosome membrane; extracellular region; Golgi cisterna; Golgi membrane; membrane; membrane raft; plasma membrane; trans-Golgi network; trans-Golgi network transport vesicle; trans-Golgi network transport v... | endopeptidase activity heparan sulfate binding heparin binding metal ion binding nerve growth factor binding peptidase activity peptide binding protease binding serine-type endopeptidase activity serine-type endopeptidase inhibitor activity serine-type peptidase activity | Mus musculus | 3D-structure Autocatalytic cleavage Calcium Cell membrane Cleavage on pair of basic residues Disulfide bond Endosome Glycoprotein Golgi apparatus Heparin-binding Hydrolase Membrane Metal-binding Phosphoprotein Protease Reference proteome Repeat Secreted Serine protease Signal Transmembrane Transmembrane helix Zymogen | MELRSWLLWV | MELRSWLLWVVAAAGAVVLLAADAQGQKIFTNTWAVHIPGGPAVADRVAQKHGFHNLGQIFGDYYHFWHRAVTKRSLSPHRPRHSRLQREPQVKWLEQQVAKRRAKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKEAWAQGFTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA... | blastocyst formation cytokine precursor processing dibasic protein processing negative regulation of low-density lipoprotein particle receptor catabolic process negative regulation of transforming growth factor beta1 production nerve growth factor production peptide biosynthetic process peptide hormone processing posit... |
DNA-templated transcription positive regulation of transcription by RNA polymerase II transcription by RNA polymerase II transcription elongation by RNA polymerase II | nucleolus; nucleoplasm; nucleus; transcription factor TFIID complex | DNA binding zinc ion binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Chromosomal rearrangement Direct protein sequencing DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MEDEVVRFAK | MEDEVVRFAKKMDKMVQKKNAAGALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC | DNA-templated transcription positive regulation of transcription by RNA polymerase II transcription by RNA polymerase II transcription elongation by RNA polymerase II nucleolus; nucleoplasm; nucleus; transcription factor TFIID complex DNA binding zinc ion binding Homo sapiens 3D-structure Acetylation Alternative splici... |
base-excision repair DNA demethylation DNA recombination DNA repair regulation of apoptotic process regulation of mRNA stability | cytoplasm; endoplasmic reticulum; mitochondrion; nuclear speck; nucleolus; nucleoplasm; nucleus; perinuclear region of cytoplasm | 3'-5' exonuclease activity chromatin DNA binding class II DNA-(apurinic or apyrimidinic site) endonuclease activity damaged DNA binding DNA binding DNA-(abasic site) binding DNA-(apurinic or apyrimidinic site) endonuclease activity double-stranded DNA 3'-5' DNA exonuclease activity metal ion binding oxidoreductase acti... | Bos taurus | Acetylation Activator Cleavage on pair of basic residues Cytoplasm Direct protein sequencing Disulfide bond DNA damage DNA recombination DNA repair DNA-binding Endonuclease Endoplasmic reticulum Exonuclease Hydrolase Magnesium Metal-binding Mitochondrion Nuclease Nucleus Phosphoprotein Reference proteome Repressor RNA-... | MPKRGKKGAV | MPKRGKKGAVVEDAEEPKTEPEAKKSKAGAKKNEKEAVGEGAVLYEDPPDQKTSPSGKSATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPVELQELSGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGEEEHDQEGRVIVAEYDAFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLTDSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLSQSVLPALCDSKIRSKALGSDHCPITLYLAL | base-excision repair DNA demethylation DNA recombination DNA repair regulation of apoptotic process regulation of mRNA stability cytoplasm; endoplasmic reticulum; mitochondrion; nuclear speck; nucleolus; nucleoplasm; nucleus; perinuclear region of cytoplasm 3'-5' exonuclease activity chromatin DNA binding class II DNA-... |
chromatin organization DNA damage response heterochromatin formation negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II rhythmic process | chromatin; chromatin lock complex; chromocenter; chromosome, centromeric region; condensed chromosome, centromeric region; euchromatin; heterochromatin; nuclear envelope; nucleoplasm; nucleus; pericentric heterochromatin; RNA polymerase II transcription regulator complex; senescence-associated heterochromatin focus; si... | chromatin binding DNA-binding transcription factor binding enzyme binding histone methyltransferase binding identical protein binding methylated histone binding protein domain specific binding transcription cis-regulatory region binding transcription coregulator binding | Mus musculus | Acetylation Biological rhythms Chromatin regulator Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Repeat Repressor Transcription Transcription regulation Ubl conjugation | MASNKTTLQK | MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEDFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPEDEAQ | chromatin organization DNA damage response heterochromatin formation negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II rhythmic process chromatin; chromatin lock complex; chromocenter; chromosome, centromeric region; condensed chromosome, centromeric region; eu... |
negative regulation of transcription by transcription factor localization nitrate assimilation protein urmylation regulation of nitrogen utilization | cytoplasm | glutathione peroxidase activity phosphoprotein binding transcription corepressor activity | Saccharomyces cerevisiae | 3D-structure Acetylation Amyloid Cytoplasm Nitrate assimilation Oxidoreductase Prion Reference proteome | MMNNNGNQVS | MMNNNGNQVSNLSNALRQVNIGNRNSNTTTDQSNINFEFSTGVNNNNNNNSSSNNNNVQNNNSGRNGSQNNDNENNIKNTLEQHRQQQQAFSDMSHVEYSRITKFFQEQPLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVV... | negative regulation of transcription by transcription factor localization nitrate assimilation protein urmylation regulation of nitrogen utilization cytoplasm glutathione peroxidase activity phosphoprotein binding transcription corepressor activity Saccharomyces cerevisiae 3D-structure Acetylation Amyloid Cytoplasm Ni... |
cyclooxygenase pathway prostaglandin biosynthetic process regulation of blood pressure regulation of cell population proliferation response to oxidative stress | cytoplasm; endoplasmic reticulum membrane; extracellular exosome; Golgi apparatus; intracellular membrane-bounded organelle; neuron projection; photoreceptor outer segment | heme binding metal ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen peroxidase activity prostaglandin-endoperoxide synthase activity | Homo sapiens | 3D-structure Alternative splicing Dioxygenase Disulfide bond EGF-like domain Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Glycoprotein Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Microsome Oxidoreductase Peroxidase Prostaglandin biosynthesis Prostaglandin metabolism Refer... | MSRSLLLWFL | MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHP... | cyclooxygenase pathway prostaglandin biosynthetic process regulation of blood pressure regulation of cell population proliferation response to oxidative stress cytoplasm; endoplasmic reticulum membrane; extracellular exosome; Golgi apparatus; intracellular membrane-bounded organelle; neuron projection; photoreceptor ou... |
activation of innate immune response alternative mRNA splicing, via spliceosome chromatin remodeling double-strand break repair via homologous recombination innate immune response mRNA processing negative regulation of circadian rhythm negative regulation of DNA-templated transcription negative regulation of transcript... | chromatin; cytosol; nuclear matrix; nuclear speck; nucleoplasm; nucleus; paraspeckles; RNA polymerase II transcription regulator complex | chromatin binding DNA binding histone deacetylase binding protein homodimerization activity RNA binding transcription cis-regulatory region binding | Homo sapiens | 3D-structure Acetylation Activator Alternative splicing Biological rhythms Chromosomal rearrangement Coiled coil Cytoplasm Direct protein sequencing DNA damage DNA recombination DNA repair DNA-binding Immunity Innate immunity Isopeptide bond Methylation mRNA processing mRNA splicing Nucleus Phosphoprotein Reference pro... | MSRDRFRSRG | MSRDRFRSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKY... | activation of innate immune response alternative mRNA splicing, via spliceosome chromatin remodeling double-strand break repair via homologous recombination innate immune response mRNA processing negative regulation of circadian rhythm negative regulation of DNA-templated transcription negative regulation of transcript... |
3'-UTR-mediated mRNA destabilization defense response to virus miRNA-mediated gene silencing by mRNA destabilization miRNA-mediated post-transcriptional gene silencing positive regulation of mRNA catabolic process regulation of neuron projection arborization regulatory ncRNA-mediated post-transcriptional gene silencing... | cytoplasmic ribonucleoprotein granule; cytoplasmic stress granule; cytosol; nucleus; P granule; P-body | 5'-3' RNA helicase activity ATP binding ATP hydrolysis activity RNA binding | Mus musculus | Acetylation ATP-binding Cytoplasm Helicase Hydrolase Nucleotide-binding Nucleus Phosphoprotein Reference proteome RNA-binding RNA-mediated gene silencing Ubl conjugation | MPSKFSCRKL | MPSKFSCRKLRETGQRFESFLAERGLDLETDRERLRTIYNHDFKPSYGTPAPGFSSMLYGMKIANLAFVTKTRVRFFKLDRWADVQLPEKRRIKPGSNISKQHRSLLARIFHDRAEYLHGKHGVDVEVQGPHEARDGQLLIHLDLNRKEVLTLRLRNGGSKPVTLTHLFPLCWTPQFVFYHGEQDLPCPLGPGESYELHIYCKTSIVGYFPATVLWELLGPGESGAEGAETFYIARFLAAVAHSPLAAQLKPTTPFKRPPRLTRNSVLTNRIEEGERPDRAKGYELELSLALGTYYPPILLRQLLPTLLQGPSIFTAPKE... | 3'-UTR-mediated mRNA destabilization defense response to virus miRNA-mediated gene silencing by mRNA destabilization miRNA-mediated post-transcriptional gene silencing positive regulation of mRNA catabolic process regulation of neuron projection arborization regulatory ncRNA-mediated post-transcriptional gene silencing... |
pentose-phosphate shunt | cytoplasm; cytosol | metal ion binding transketolase activity | Saccharomyces cerevisiae | 3D-structure Calcium Direct protein sequencing Isopeptide bond Magnesium Metal-binding Phosphoprotein Reference proteome Thiamine pyrophosphate Transferase Ubl conjugation | MTQFTDIDKL | MTQFTDIDKLAVSTIRILAVDTVSKANSGHPGAPLGMAPAAHVLWSQMRMNPTNPDWINRDRFVLSNGHAVALLYSMLHLTGYDLSIEDLKQFRQLGSRTPGHPEFELPGVEVTTGPLGQGISNAVGMAMAQANLAATYNKPGFTLSDNYTYVFLGDGCLQEGISSEASSLAGHLKLGNLIAIYDDNKITIDGATSISFDEDVAKRYEAYGWEVLYVENGNEDLAGIAKAIAQAKLSKDKPTLIKMTTTIGYGSLHAGSHSVHGAPLKADDVKQLKSKFGFNPDKSFVVPQEVYDHYQKTILKPGVEANNKWNKLFSEYQ... | pentose-phosphate shunt cytoplasm; cytosol metal ion binding transketolase activity Saccharomyces cerevisiae 3D-structure Calcium Direct protein sequencing Isopeptide bond Magnesium Metal-binding Phosphoprotein Reference proteome Thiamine pyrophosphate Transferase Ubl conjugation MTQFTDIDKL MTQFTDIDKLAVSTIRILAVDTVSKAN... |
centriole-centriole cohesion centrosome cycle cytoplasmic microtubule organization meiotic spindle organization microtubule nucleation mitotic cell cycle mitotic sister chromatid segregation mitotic sister chromatid separation mitotic spindle organization regulation of cell cycle | centrosome; cytoplasm; gamma-tubulin complex; gamma-tubulin ring complex; gamma-tubulin small complex; microtubule; nucleus; pericentriolar material; spindle | GTP binding guanyl nucleotide binding structural constituent of cytoskeleton | Drosophila melanogaster | Cytoplasm Cytoskeleton GTP-binding Microtubule Nucleotide-binding Reference proteome | MPSEIITLQL | MPSEIITLQLGQCGNQIGFEFWKRLCLEHGISPSGVLEDFANDGLDRKDVFFYQADDDHYIPRAVLLDLEPRVINTIMGSVYSKLYNPENVYLSKHGGGAGNNWASGYSQGEKLQEEVFDIIDREADGSDSLEGFILCHSIAGGTGSGMGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPYNSMLTLKRLTTAADSVVVLDNTALNRIACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNNNLIGLTAPLIPTPQLHFLMTGYTPLTSDSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDKSNHH... | centriole-centriole cohesion centrosome cycle cytoplasmic microtubule organization meiotic spindle organization microtubule nucleation mitotic cell cycle mitotic sister chromatid segregation mitotic sister chromatid separation mitotic spindle organization regulation of cell cycle centrosome; cytoplasm; gamma-tubulin co... |
cytoplasmic microtubule organization meiotic spindle organization microtubule cytoskeleton organization microtubule nucleation mitotic cell cycle mitotic sister chromatid segregation mitotic spindle organization | apical part of cell; cell leading edge; centriole; centrosome; ciliary basal body; condensed nuclear chromosome; cytoplasm; cytoplasmic microtubule; cytosol; gamma-tubulin complex; microtubule; mitotic spindle microtubule; neuron projection; non-motile cilium; nucleus; pericentriolar material; polar microtubule; recycl... | GTP binding identical protein binding structural constituent of cytoskeleton | Homo sapiens | 3D-structure Cytoplasm Cytoskeleton Disease variant GTP-binding Lissencephaly Microtubule Nucleotide-binding Phosphoprotein Reference proteome | MPREIITLQL | MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAI... | cytoplasmic microtubule organization meiotic spindle organization microtubule cytoskeleton organization microtubule nucleation mitotic cell cycle mitotic sister chromatid segregation mitotic spindle organization apical part of cell; cell leading edge; centriole; centrosome; ciliary basal body; condensed nuclear chromos... |
detection of chemical stimulus involved in sensory perception detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway sensory perception of smell | cell cortex; endoplasmic reticulum membrane; membrane; plasma membrane | G protein-coupled receptor activity odorant binding olfactory receptor activity | Mus musculus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Olfaction Receptor Reference proteome Sensory transduction Transducer Transmembrane Transmembrane helix | MEVDSNSSSG | MEVDSNSSSGSFILMGVSDHPHLEIIFFAVILASYLLTLVGNLTIILLSRLDARLHTPMYFFLSNLSSLDLAFTTSSVPQMLKNLWGPDKTISYGGCVTQLYVFLWLGATECILLVVMAFDRYVAVCRPLHYMTVMNPRLCWGLAAISWLGGLGNSVIQSTFTLQLPFCGHRKVDNFLCEVPAMIKLACGDTSLNEAVLNGVCTFFTVVPVSVILVSYCFIAQAVMKIRSVEGRRKAFNTCVSHLVVVFLFYGSAIYGYLLPAKSSNQSQGKFISLFYSVVTPMVNPLIYTLRNKEVKGALGRLLGKGRGAS | detection of chemical stimulus involved in sensory perception detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway sensory perception of smell cell cortex; endoplasmic reticulum membrane; membrane; plasma membrane G protein-coupled receptor activity odorant... |
establishment of localization in cell intracellular calcium ion homeostasis intracellular magnesium ion homeostasis myelination negative regulation of potassium ion transmembrane transport potassium ion transmembrane transport protein processing regulation of axon diameter regulation of cell size skeletal muscle fiber ... | cytosol; Golgi apparatus; membrane; nucleoplasm; plasma membrane | metal ion binding metalloendopeptidase activity | Homo sapiens | Blood group antigen Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Membrane Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Signal-anchor Transmembrane Transmembrane helix Zinc | MEGGDQSEEE | MEGGDQSEEEPRERSQAGGMGTLWSQESTPEERLPVEGSRPWAVARRVLTAILILGLLLCFSVLLFYNFQNCGPRPCETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRAKETNNSFQELATKNKNRLRRILEVQNSWHPGSGEEKAFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRISGKWTSLNFNRTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQEQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKLFQMVTIDQLKEMAPAIDWLSCL... | establishment of localization in cell intracellular calcium ion homeostasis intracellular magnesium ion homeostasis myelination negative regulation of potassium ion transmembrane transport potassium ion transmembrane transport protein processing regulation of axon diameter regulation of cell size skeletal muscle fiber ... |
detection of chemical stimulus involved in sensory perception of bitter taste one-carbon metabolic process | cytosol; extracellular exosome; extracellular region; extracellular space | carbonate dehydratase activity zinc ion binding | Homo sapiens | 3D-structure Alternative splicing Disulfide bond Glycoprotein Lyase Metal-binding Reference proteome Secreted Signal Zinc | MRALVLLLSL | MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEILDYLRRALN | detection of chemical stimulus involved in sensory perception of bitter taste one-carbon metabolic process cytosol; extracellular exosome; extracellular region; extracellular space carbonate dehydratase activity zinc ion binding Homo sapiens 3D-structure Alternative splicing Disulfide bond Glycoprotein Lyase Metal-bind... |
bone development chaperone-mediated protein folding neutrophil chemotaxis positive regulation by host of viral genome replication positive regulation by host of viral process positive regulation of multicellular organism growth protein folding protein peptidyl-prolyl isomerization protein stabilization | cytoplasm; cytosol; endoplasmic reticulum; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen; extracellular exosome; focal adhesion; intracellular membrane-bounded organelle; melanosome; membrane; nucleoplasm; nucleus; perinuclear region of cytoplasm; protein-containing complex; smooth endoplasmic re... | cyclosporin A binding peptidyl-prolyl cis-trans isomerase activity RNA binding RNA polymerase binding unfolded protein binding | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Disease variant Dwarfism Endoplasmic reticulum Glycoprotein Isomerase Osteogenesis imperfecta Reference proteome Rotamase S-nitrosylation Signal Virion | MLRLSERNMK | MLRLSERNMKVLLAAALIAGSVFFLLLPGPSAADEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE | bone development chaperone-mediated protein folding neutrophil chemotaxis positive regulation by host of viral genome replication positive regulation by host of viral process positive regulation of multicellular organism growth protein folding protein peptidyl-prolyl isomerization protein stabilization cytoplasm; cytos... |
calcineurin-mediated signaling cellular response to pheromone fungal-type cell wall organization intracellular monoatomic ion homeostasis positive regulation of DNA-templated transcription regulation of cell morphogenesis | calcineurin complex; cytoplasm | calmodulin binding calmodulin-dependent protein phosphatase activity metal ion binding myosin phosphatase activity | Saccharomyces cerevisiae | 3D-structure Acetylation Calmodulin-binding Hydrolase Iron Metal-binding Protein phosphatase Reference proteome Zinc | MSKDLNSSRI | MSKDLNSSRIKIIKPNDSYIKVDRKKDLTKYELENGKVISTKDRPIASVPAITGKIPSDEEVFDSKTGLPNHSFLREHFFHEGRLSKEQAIKILNMSTVALSKEPNLLKLKAPITICGDIHGQYYDLLKLFEVGGDPAEIDYLFLGDYVDRGAFSFECLIYLYSLKLNNLGRFWMLRGNHECKHLTSYFTFKNEMLHKYDMEVYDACCRSFNVLPLAALMNGQYFCVHGGISPELKSVEDVNKINRFREIPSRGLMCDLLWADPVENYDDARDGSEFDQSEDEFVPNSLRGCSFAFTFKASCKFLKANGLLSIIRAHEAQ... | calcineurin-mediated signaling cellular response to pheromone fungal-type cell wall organization intracellular monoatomic ion homeostasis positive regulation of DNA-templated transcription regulation of cell morphogenesis calcineurin complex; cytoplasm calmodulin binding calmodulin-dependent protein phosphatase activit... |
cell morphogenesis endocytosis glucose mediated signaling pathway phosphorylation response to glucose signal transduction | cell periphery; endoplasmic reticulum; mitochondrial membrane; mitochondrion; nucleus; plasma membrane | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Cell membrane Kinase Lipoprotein Membrane Mitochondrion Nucleotide-binding Palmitate Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MSMPIASTTL | MSMPIASTTLAVNNLTNINGNANFNVQANKQLHHQAVDSPARSSMTATTAANSNSNSSRDDSTIVGLHYKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKILNGTPNIPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRKFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLAQGLPVQFGRYLEIVRSL... | cell morphogenesis endocytosis glucose mediated signaling pathway phosphorylation response to glucose signal transduction cell periphery; endoplasmic reticulum; mitochondrial membrane; mitochondrion; nucleus; plasma membrane ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kin... |
cell morphogenesis endocytosis glucose mediated signaling pathway phosphorylation response to glucose signal transduction | cell periphery; cellular bud neck; mating projection; nucleus; plasma membrane | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Saccharomyces cerevisiae | Acetylation ATP-binding Cell membrane Isopeptide bond Kinase Lipoprotein Membrane Nucleotide-binding Palmitate Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Ubl conjugation | MSQVQSPLTA | MSQVQSPLTATNSGLAVNNNTMNSQMPNRSNVRLVNGTLPPSLHVSSNLNHNTGNSSASYSGSQSRDDSTIVGLHYKIGKKIGEGSFGVLFEGTNMINGLPVAIKFEPRKTEAPQLKDEYRTYKILAGTPGIPQEYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANKVHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEAMGHVFFYFLRGQLPWQGLKAPNNKQKYEKIGEKKRLTNVYDLAQGLPIQFGRY... | cell morphogenesis endocytosis glucose mediated signaling pathway phosphorylation response to glucose signal transduction cell periphery; cellular bud neck; mating projection; nucleus; plasma membrane ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity Saccharomyc... |
DNA-templated transcription phosphorylation positive regulation of transcription elongation by RNA polymerase II transcription elongation by RNA polymerase II | cyclin-dependent protein kinase holoenzyme complex; nucleus | ATP binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity | Saccharomyces cerevisiae | ATP-binding Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MSDNGSPAVL | MSDNGSPAVLPKTEFNKYKIGKVKSTPAIQRDAKTNLTYIKLRKRSSEKVYGCTVFQNHYREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGAELTT... | DNA-templated transcription phosphorylation positive regulation of transcription elongation by RNA polymerase II transcription elongation by RNA polymerase II cyclin-dependent protein kinase holoenzyme complex; nucleus ATP binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity ... |
intracellular signal transduction positive regulation of nitric-oxide synthase activity positive regulation of sprouting angiogenesis regulation of heart contraction substantia nigra development | cytoplasm; cytosol; extracellular region; Golgi apparatus; mitochondrion; nucleoplasm; nucleus; protein-containing complex; sarcoplasmic reticulum | ATPase binding calcium ion binding calcium-dependent protein binding identical protein binding protein homodimerization activity S100 protein binding | Homo sapiens | 3D-structure Calcium Cytoplasm Glutathionylation Metal-binding Mitochondrion Reference proteome Repeat S-nitrosylation Sarcoplasmic reticulum | MGSELETAME | MGSELETAMETLINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVAALTVACNNFFWENS | intracellular signal transduction positive regulation of nitric-oxide synthase activity positive regulation of sprouting angiogenesis regulation of heart contraction substantia nigra development cytoplasm; cytosol; extracellular region; Golgi apparatus; mitochondrion; nucleoplasm; nucleus; protein-containing complex; s... |
cell differentiation cellular response to amino acid starvation intracellular signal transduction negative regulation of glial cell apoptotic process negative regulation of translation positive regulation of B cell receptor signaling pathway positive regulation of glial cell proliferation positive regulation of keratin... | cell-cell junction; cytoplasm; cytosol; plasma membrane | ATP binding diacylglycerol-dependent, calcium-independent serine/threonine kinase activity enzyme binding metal ion binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase binding protein serine/threonine kinase inhibitor activity small GTP... | Mus musculus | ATP-binding Cytoplasm Differentiation Kinase Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase Zinc Zinc-finger | MSSGTMKFNG | MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTKQKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTAGTSDTFEGWVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQVNGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDAKIAEQRFGINIPHKFNVHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNISPTS... | cell differentiation cellular response to amino acid starvation intracellular signal transduction negative regulation of glial cell apoptotic process negative regulation of translation positive regulation of B cell receptor signaling pathway positive regulation of glial cell proliferation positive regulation of keratin... |
cardiac muscle cell action potential involved in contraction cellular response to acidic pH cellular response to cAMP cellular response to light stimulus epithelial cell maturation heart contraction male gonad development membrane repolarization membrane repolarization during action potential membrane repolarization du... | apical plasma membrane; cell surface; membrane raft; plasma membrane; voltage-gated potassium channel complex; Z disc | delayed rectifier potassium channel activity potassium channel regulator activity protein-containing complex binding telethonin binding transmembrane transporter binding | Mus musculus | Cell membrane Direct protein sequencing Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MSLPNSTTVL | MSLPNSTTVLPFLARLWQETAEQGGNVSGLARKSQLRDDSKLEALYILMVLGFFGFFTLGIMLSYIRSKKLEHSHDPFNVYIESDAWQEKGKAVFQARVLESFRACYVIENQAAVEQPATHLPELKPLS | cardiac muscle cell action potential involved in contraction cellular response to acidic pH cellular response to cAMP cellular response to light stimulus epithelial cell maturation heart contraction male gonad development membrane repolarization membrane repolarization during action potential membrane repolarization du... |
CAT tailing positive regulation of cytoplasmic translational elongation through polyproline stretches positive regulation of translational elongation positive regulation of translational initiation positive regulation of translational termination rescue of stalled ribosome translational elongation translational framesh... | cytoplasm; mitochondrion; perinuclear region of cytoplasm | ribosome binding RNA binding translation elongation factor activity translation initiation factor activity | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Direct protein sequencing Elongation factor Hypusine Isopeptide bond Phosphoprotein Protein biosynthesis Reference proteome RNA-binding Ubl conjugation | MSDEEHTFET | MSDEEHTFETADAGSSATYPMQCSALRKNGFVVIKSRPCKIVDMSTSKTGKHGHAKVHLVAIDIFTGKKLEDLSPSTHNMEVPVVKRNEYQLLDIDDGFLSLMNMDGDTKDDVKAPEGELGDSLQTAFDEGKDLMVTIISAMGEEAAISFKEAARTD | CAT tailing positive regulation of cytoplasmic translational elongation through polyproline stretches positive regulation of translational elongation positive regulation of translational initiation positive regulation of translational termination rescue of stalled ribosome translational elongation translational framesh... |
photoinhibition photosynthesis, light reaction photosystem II assembly photosystem II stabilization regulation of protein dephosphorylation | apoplast; chloroplast; chloroplast stroma; chloroplast thylakoid; chloroplast thylakoid lumen; chloroplast thylakoid membrane; photosystem II oxygen evolving complex; plastid; plastid thylakoid membrane; plastoglobule; thylakoid; thylakoid lumen | mRNA binding oxygen evolving activity poly(U) RNA binding | Arabidopsis thaliana | 3D-structure Chloroplast Direct protein sequencing Manganese Membrane Photosynthesis Photosystem II Plastid Reference proteome Thylakoid Transit peptide | MAASLQSTAT | MAASLQSTATFLQSAKIATAPSRGSSHLRSTQAVGKSFGLETSSARLTCSFQSDFKDFTGKCSDAVKIAGFALATSALVVSGASAEGAPKRLTYDEIQSKTYMEVKGTGTANQCPTIDGGSETFSFKPGKYAGKKFCFEPTSFTVKADSVSKNAPPEFQNTKLMTRLTYTLDEIEGPFEVASDGSVNFKEEDGIDYAAVTVQLPGGERVPFLFTVKQLDASGKPDSFTGKFLVPSYRGSSFLDPKGRGGSTGYDNAVALPAGGRGDEEELVKENVKNTAASVGEITLKVTKSKPETGEVIGVFESLQPSDTDLGAKVPKD... | photoinhibition photosynthesis, light reaction photosystem II assembly photosystem II stabilization regulation of protein dephosphorylation apoplast; chloroplast; chloroplast stroma; chloroplast thylakoid; chloroplast thylakoid lumen; chloroplast thylakoid membrane; photosystem II oxygen evolving complex; plastid; plas... |
muscle contraction positive regulation of heart contraction positive regulation of heart rate positive regulation of relaxation of cardiac muscle regulation of calcium ion transmembrane transport regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion regulation of cell communic... | endoplasmic reticulum lumen; sarcoplasmic reticulum lumen; sarcoplasmic reticulum membrane; Z disc | ATPase binding calcium ion binding transmembrane transporter binding | Homo sapiens | Calcium Phosphoprotein Reference proteome Repeat Sarcoplasmic reticulum Signal | MGHHRPWLHA | MGHHRPWLHASVLWAGVASLLLPPAMTQQLRGDGLGFRNRNNSTGVAGLSEEASAELRHHLHSPRDHPDENKDVSTENGHHFWSHPDREKEDEDVSKEYGHLLPGHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEEDDNDDDDVSTEYGHQAHR... | muscle contraction positive regulation of heart contraction positive regulation of heart rate positive regulation of relaxation of cardiac muscle regulation of calcium ion transmembrane transport regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion regulation of cell communic... |
carbohydrate metabolic process lipid glycosylation protein glycosylation | Golgi apparatus; Golgi cisterna; Golgi cisterna membrane; vesicle | glycosyltransferase activity metal ion binding N-acetyllactosaminide 3-alpha-galactosyltransferase activity | Mus musculus | Alternative splicing Glycoprotein Glycosyltransferase Golgi apparatus Manganese Membrane Metal-binding Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MITMLQDLHV | MITMLQDLHVNKISMSRSKSETSLPSSRSGSQEKIMNVKGKVILLMLIVSTVVVVFWEYVNRIPEVGENRWQKDWWFPSWFKNGTHSYQEDNVEGRREKGRNGDRIEEPQLWDWFNPKNRPDVLTVTPWKAPIVWEGTYDTALLEKYYATQKLTVGLTVFAVGKYIEHYLEDFLESADMYFMVGHRVIFYVMIDDTSRMPVVHLNPLHSLQVFEIRSEKRWQDISMMRMKTIGEHILAHIQHEVDFLFCMDVDQVFQDNFGVETLGQLVAQLQAWWYKASPEKFTYERRELSAAYIPFGEGDFYYHAAIFGGTPTHILNL... | carbohydrate metabolic process lipid glycosylation protein glycosylation Golgi apparatus; Golgi cisterna; Golgi cisterna membrane; vesicle glycosyltransferase activity metal ion binding N-acetyllactosaminide 3-alpha-galactosyltransferase activity Mus musculus Alternative splicing Glycoprotein Glycosyltransferase Golgi ... |
glycogen biosynthetic process | cytoplasm; mitochondrion | glycogen (starch) synthase activity | Saccharomyces cerevisiae | Allosteric enzyme Direct protein sequencing Glycogen biosynthesis Glycosyltransferase Phosphoprotein Reference proteome Transferase | MARDLQNHLL | MARDLQNHLLFEVATEVTNRVGGIYSVLKSKAPVTVAQYGDNYTLLGPLNKATYESEVEKLDWEDESIFPEELLPIQKTLMSMREKGVNFVYGNWLIEGAPRVILFELDSVRHFLNEWKADLWSLVGIPSPEHDHETNDAILLGYVVVWFLGEVSKLDSSHAIIGHFHEWLAGVALPLCRKKRIDVVTIFTTHATLLGRYLCAAGDVDFYNNLQYFDVDQEAGKRGIYHRYCIERAAAHTADVFTTVSQITALEAEHLLKRKPDGILPNGLNVVKFQAVHEFQNLHALKKDKINDFVRGHFHGCFDFDLDNTVYFFIAGR... | glycogen biosynthetic process cytoplasm; mitochondrion glycogen (starch) synthase activity Saccharomyces cerevisiae Allosteric enzyme Direct protein sequencing Glycogen biosynthesis Glycosyltransferase Phosphoprotein Reference proteome Transferase MARDLQNHLL MARDLQNHLLFEVATEVTNRVGGIYSVLKSKAPVTVAQYGDNYTLLGPLNKATYESEVEK... |
axon guidance cell adhesion chemotaxis neuron differentiation | cell surface; extracellular matrix; extracellular region; extracellular space; plasma membrane | extracellular matrix structural constituent heparin binding serine-type endopeptidase inhibitor activity | Homo sapiens | 3D-structure Cell adhesion Cell membrane Chemotaxis Disease variant Disulfide bond Glycoprotein Heparin-binding Hypogonadotropic hypogonadism Kallmann syndrome Membrane Protease inhibitor Reference proteome Repeat Secreted Serine protease inhibitor Signal | MVPGVPGAVL | MVPGVPGAVLTLCLWLAASSGCLAAGPGAAAARRLDESLSAGSVQRARCASRCLSLQITRISAFFQHFQNNGSLVWCQNHKQCSKCLEPCKESGDLRKHQCQSFCEPLFPKKSYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVDNECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEPVIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQLTDIRPSRWYQFRVAAVNVHGTRGFTAPSKHFRSSKDPSAPPAPANLRLANSTVNSDGSVTVTIVWDLPEE... | axon guidance cell adhesion chemotaxis neuron differentiation cell surface; extracellular matrix; extracellular region; extracellular space; plasma membrane extracellular matrix structural constituent heparin binding serine-type endopeptidase inhibitor activity Homo sapiens 3D-structure Cell adhesion Cell membrane Chem... |
mismatch repair mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication nucleotide-excision repair, DNA duplex unwinding regulation of DNA recombination | mismatch repair complex; single-stranded DNA-dependent ATP-dependent DNA helicase complex | ATP binding ATP hydrolysis activity ATP-dependent DNA damage sensor activity DNA binding identical protein binding mismatched DNA binding | Escherichia coli | 3D-structure ATP-binding DNA damage DNA repair Nucleotide-binding Reference proteome | MPIQVLPPQL | MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDIERGGAKLIRIRDNGCGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASISSVSRLTLTSRTAEQQEAWQAYAEGRDMNVTVKPAAHPVGTTLEVLDLFYNTPARRKFLRTEKTEFNHIDEIIRRIALARFDVTINLSHNGKIVRQYRAVPEGGQKERRLGAICGTAFLEQALAIEWQHGDLTLRGWVADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQACEDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHD... | mismatch repair mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication nucleotide-excision repair, DNA duplex unwinding regulation of DNA recombination mismatch repair complex; single-stranded DNA-dependent ATP-dependent DNA helicase complex ATP binding ATP hydrolysis activity ATP... |
malate metabolic process pyruvate metabolic process regulation of NADP metabolic process | intracellular membrane-bounded organelle; mitochondrial matrix; mitochondrion | electron transfer activity malate dehydrogenase (decarboxylating) (NAD+) activity malate dehydrogenase (decarboxylating) (NADP+) activity malic enzyme activity metal ion binding NAD binding oxaloacetate decarboxylase activity | Homo sapiens | 3D-structure Acetylation Allosteric enzyme Alternative splicing Direct protein sequencing Metal-binding Mitochondrion NAD Oxidoreductase Reference proteome Transit peptide | MLSRLRVVST | MLSRLRVVSTTCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISKPISEHKILFLGAGEAALGIA... | malate metabolic process pyruvate metabolic process regulation of NADP metabolic process intracellular membrane-bounded organelle; mitochondrial matrix; mitochondrion electron transfer activity malate dehydrogenase (decarboxylating) (NAD+) activity malate dehydrogenase (decarboxylating) (NADP+) activity malic enzyme ac... |
blastocyst formation cytokine precursor processing dibasic protein processing negative regulation of low-density lipoprotein particle receptor catabolic process negative regulation of transforming growth factor beta1 production nerve growth factor production peptide biosynthetic process peptide hormone processing posit... | cell surface; endoplasmic reticulum; endoplasmic reticulum membrane; endosome membrane; extracellular region; Golgi cisterna; Golgi membrane; membrane; membrane raft; plasma membrane; trans-Golgi network; trans-Golgi network transport vesicle | endopeptidase activity heparan sulfate binding heparin binding metal ion binding nerve growth factor binding peptidase activity peptide binding protease binding serine-type endopeptidase activity serine-type endopeptidase inhibitor activity serine-type peptidase activity | Rattus norvegicus | Autocatalytic cleavage Calcium Cell membrane Cleavage on pair of basic residues Disulfide bond Endosome Glycoprotein Golgi apparatus Heparin-binding Hydrolase Membrane Metal-binding Phosphoprotein Protease Reference proteome Repeat Secreted Serine protease Signal Transmembrane Transmembrane helix Zymogen | MELRPWLLWV | MELRPWLLWVVAAAGALVLLAAEARGQKIFTNTWAVHISGGPAVADSVARKHGFHNLGQIFGDYYHFWHRAVTKRSLSPHRPRHSRLQRVPQVKWLEQQVAKQRAKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKEAWAQGFTGRGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA... | blastocyst formation cytokine precursor processing dibasic protein processing negative regulation of low-density lipoprotein particle receptor catabolic process negative regulation of transforming growth factor beta1 production nerve growth factor production peptide biosynthetic process peptide hormone processing posit... |
cellular response to leukemia inhibitory factor glycine catabolic process glycine decarboxylation via glycine cleavage system response to lipoic acid response to methylamine | glycine cleavage complex; mitochondrial matrix; mitochondrion; nucleoplasm; plasma membrane | electron transfer activity glycine binding glycine dehydrogenase (decarboxylating) activity lyase activity protein homodimerization activity pyridoxal binding pyridoxal phosphate binding | Homo sapiens | 3D-structure Acetylation Disease variant Mitochondrion Oxidoreductase Pyridoxal phosphate Reference proteome Transit peptide | MQSCARAWGL | MQSCARAWGLRLGRGVGGGRRLAGGSGPCWAPRSRDSSSGGGDSAAAGASRLLERLLPRHDDFARRHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLKRPLKMEDPVCENEILATLHAISSKNQIWRSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESLLNYQTMVCDITGLDMANASLLDEGTAAAEALQLCYRHNKRRKFLVDPRCHPQTIAVVQTRAKYTGVLTELKLPCEMDFSGKDVSGVLFQYPDTEGKVEDFTELVERAHQSGSLACCATDLLALCILRPPGEFGVDIALGSSQRF... | cellular response to leukemia inhibitory factor glycine catabolic process glycine decarboxylation via glycine cleavage system response to lipoic acid response to methylamine glycine cleavage complex; mitochondrial matrix; mitochondrion; nucleoplasm; plasma membrane electron transfer activity glycine binding glycine deh... |
dsRNA transport proton transmembrane transport vacuolar acidification | fusome; plasma membrane proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V0 domain | proton-transporting ATPase activity, rotational mechanism | Drosophila melanogaster | Hydrogen ion transport Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport | MSSEVSSDNP | MSSEVSSDNPIYGPFFGVMGAASAIIFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAGALEEPSKYSLYRGFIHLGAGLAVGFSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAIYLYTK | dsRNA transport proton transmembrane transport vacuolar acidification fusome; plasma membrane proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V0 domain proton-transporting ATPase activity, rotational mechanism Drosophila melanogaster Hydrogen ion transport Ion transport Membrane R... |
angiogenesis negative regulation of cell population proliferation negative regulation of protein kinase activity positive regulation of gene expression positive regulation of protein-containing complex assembly regulation of angiogenesis translation tryptophanyl-tRNA aminoacylation | cytoplasm; cytosol; extracellular exosome; nucleus; protein-containing complex | ATP binding kinase inhibitor activity protein domain specific binding protein homodimerization activity protein kinase binding tryptophan-tRNA ligase activity | Homo sapiens | 3D-structure Alternative splicing Aminoacyl-tRNA synthetase Angiogenesis ATP-binding Cytoplasm Direct protein sequencing Disease variant Intellectual disability Ligase Neurodegeneration Neuropathy Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome | MPNSEPASLL | MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKADCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMT... | angiogenesis negative regulation of cell population proliferation negative regulation of protein kinase activity positive regulation of gene expression positive regulation of protein-containing complex assembly regulation of angiogenesis translation tryptophanyl-tRNA aminoacylation cytoplasm; cytosol; extracellular exo... |
immune response necroptotic signaling pathway positive regulation of NF-kappaB transcription factor activity regulation of biological quality regulation of developmental process regulation of multicellular organismal process regulation of secretion vascular endothelial growth factor production | extracellular space; plasma membrane | cytokine activity tumor necrosis factor receptor binding | Ovis aries | Cell membrane Cytokine Disulfide bond Glycoprotein Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Secreted Signal-anchor Transmembrane Transmembrane helix | MSTKSMIRDV | MSTKSMIRDVELAEEVLSNKAGGPQGSRSCWCLSLFSFLLVAGATTLFCLLHFGVIGPQREEQSPAGPSFNRPLVQTLRSSSQASNNKPVAHVVANISAPGQLRWGDSYANALMANGVELKDNQLVVPTDGLYLIYSQVLFRGHGCPSTPLFLTHTISRIAVSYQTKVNILSAIKSPCHRETLEGAEAKPWYEPIYQGGVFQLEKGDRLSAEINLPEYLDYAESGQVYFGIIAL | immune response necroptotic signaling pathway positive regulation of NF-kappaB transcription factor activity regulation of biological quality regulation of developmental process regulation of multicellular organismal process regulation of secretion vascular endothelial growth factor production extracellular space; plas... |
mRNA 5'-splice site recognition mRNA splicing, via spliceosome | catalytic step 2 spliceosome; cytoplasm; nucleus; spliceosomal complex; U4/U6 x U5 tri-snRNP complex; U5 snRNP | ATP binding ATP hydrolysis activity first spliceosomal transesterification activity RNA binding RNA helicase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Cytoplasm Helicase Hydrolase mRNA processing mRNA splicing Nucleotide-binding Nucleus Phosphoprotein Reference proteome | MARPIDVSQL | MARPIDVSQLIAGINKKKGLDENTSGKISKPRFLNKQERSKQERLKENEESLTPTQSDSAKVEIKKVNSRDDSFFNETNDKKRNPSKQNGSKFHFSWNESEDTLSGYDPIVSTRAIDLLWKGKTPKNAAESSYMGKHWTEKSLHEMNERDWRILKEDYAIVTKGGTVENPLRNWEELNIIPRDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVASTGSGKTLAFVIPILIKMSRSPPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKIWSKESNYDCKVISIVGGHSLEEISFSLSEGCDILVATPGR... | mRNA 5'-splice site recognition mRNA splicing, via spliceosome catalytic step 2 spliceosome; cytoplasm; nucleus; spliceosomal complex; U4/U6 x U5 tri-snRNP complex; U5 snRNP ATP binding ATP hydrolysis activity first spliceosomal transesterification activity RNA binding RNA helicase activity Saccharomyces cerevisiae 3D... |
muscle cell fate commitment muscle tissue morphogenesis negative regulation of DNA-templated transcription positive regulation of myoblast differentiation positive regulation of skeletal muscle fiber development positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II s... | chromatin; cytosol; mitotic spindle; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded D... | Homo sapiens | Developmental protein Differentiation Disease variant DNA-binding Myogenesis Nucleus Reference proteome | MMMDLFETGS | MMMDLFETGSYFFYLDGENVTLQPLEVAEGSPLYPGSDGTLSPCQDQMPPEAGSDSSGEEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKRRTVANPNQRLPKVEILRSAISYIERLQDLLHRLDQQEKMQELGVDPFSYRPKQENLEGADFLRTCSSQWPSVSDHSRGLVITAKEGGASIDSSASSSLRCLSSIVDSISSEERKLPCVEEVVEK | muscle cell fate commitment muscle tissue morphogenesis negative regulation of DNA-templated transcription positive regulation of myoblast differentiation positive regulation of skeletal muscle fiber development positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II s... |
acrosome reaction adult walking behavior cellular response to amino acid stimulus cellular response to ethanol cellular response to zinc ion chloride transmembrane transport chloride transport inhibitory postsynaptic potential monoatomic ion transport muscle contraction negative regulation of transmission of nerve impu... | chloride channel complex; dendrite; external side of plasma membrane; glycinergic synapse; inhibitory synapse; intracellular membrane-bounded organelle; membrane; neuron projection; neuronal cell body; perikaryon; plasma membrane; postsynaptic membrane; synapse | extracellularly glycine-gated chloride channel activity glycine binding identical protein binding ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential taurine binding transmembrane signaling receptor activity transmitter-gated monoatomic ion channel activity involved in ... | Homo sapiens | 3D-structure Alternative splicing Cell membrane Cell projection Chloride Chloride channel Disease variant Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Metal-binding Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transpor... | MYSFNTLRLY | MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLL... | acrosome reaction adult walking behavior cellular response to amino acid stimulus cellular response to ethanol cellular response to zinc ion chloride transmembrane transport chloride transport inhibitory postsynaptic potential monoatomic ion transport muscle contraction negative regulation of transmission of nerve impu... |
cellular response to amino acid stimulus cellular response to ethanol cellular response to zinc ion chloride transmembrane transport monoatomic ion transmembrane transport neuropeptide signaling pathway response to amino acid | chloride channel complex; glycinergic synapse; intracellular membrane-bounded organelle; neuron projection; plasma membrane; postsynaptic membrane; synapse | extracellularly glycine-gated chloride channel activity glycine binding glycine-gated chloride ion channel activity metal ion binding transmembrane signaling receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Homo sapiens | 3D-structure Alternative splicing Cell membrane Cell projection Chloride Chloride channel Disease variant Disulfide bond Glycoprotein Intellectual disability Ion channel Ion transport Ligand-gated ion channel Membrane Metal-binding Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Tran... | MNRQLVNILT | MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIW... | cellular response to amino acid stimulus cellular response to ethanol cellular response to zinc ion chloride transmembrane transport monoatomic ion transmembrane transport neuropeptide signaling pathway response to amino acid chloride channel complex; glycinergic synapse; intracellular membrane-bounded organelle; neuro... |
glycine catabolic process glycine decarboxylation via glycine cleavage system protein lipoylation | cytoplasm; glycine cleavage complex; mitochondrial matrix; mitochondrion | aminomethyltransferase activity | Homo sapiens | Disease variant Lipoyl Mitochondrion Neurodegeneration Reference proteome Transit peptide | MALRVVRSVR | MALRVVRSVRALLCTLRAVPSPAAPCPPRPWQLGVGAVRTLRTGPALLSVRKFTEKHEWVTTENGIGTVGISNFAQEALGDVVYCSLPEVGTKLNKQDEFGALESVKAASELYSPLSGEVTEINEALAENPGLVNKSCYEDGWLIKMTLSNPSELDELMSEEAYEKYIKSIEE | glycine catabolic process glycine decarboxylation via glycine cleavage system protein lipoylation cytoplasm; glycine cleavage complex; mitochondrial matrix; mitochondrion aminomethyltransferase activity Homo sapiens Disease variant Lipoyl Mitochondrion Neurodegeneration Reference proteome Transit peptide MALRVVRSVR MAL... |
cerebellar granule cell differentiation chemical synaptic transmission establishment of localization in cell heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules maintenance of synapse structure negative regulation of excitatory postsynaptic potential negative regulation of inhibitory synapse ass... | collagen-containing extracellular matrix; extracellular region; glutamatergic synapse; parallel fiber to Purkinje cell synapse; postsynaptic membrane; synaptic cleft | identical protein binding | Homo sapiens | 3D-structure Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Membrane Postsynaptic cell membrane Reference proteome Secreted Sialic acid Signal Synapse | MLGVLELLLL | MLGVLELLLLGAAWLAGPARGQNETEPIVLEGKCLVVCDSNPTSDPTGTALGISVRSGSAKVAFSAIRSTNHEPSEMSNRTMIIYFDQVLVNIGNNFDSERSTFIAPRKGIYSFNFHVVKVYNRQTIQVSLMLNGWPVISAFAGDQDVTREAASNGVLIQMEKGDRAYLKLERGNLMGGWKYSTFSGFLVFPL | cerebellar granule cell differentiation chemical synaptic transmission establishment of localization in cell heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules maintenance of synapse structure negative regulation of excitatory postsynaptic potential negative regulation of inhibitory synapse ass... |
entrainment of circadian clock by photoperiod retina development in camera-type eye signal transduction visual perception | photoreceptor disc membrane; photoreceptor outer segment membrane | 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity metal ion binding | Bos taurus | 3D-structure Acetylation Cell projection cGMP Hydrolase Lipoprotein Membrane Metal-binding Methylation Prenylation Reference proteome Repeat Sensory transduction Vision | MSLSEGQVHR | MSLSEGQVHRFLDQNPGFADQYFGRKLSPEDVANACEDGCPEGCTSFRELCQVEESAALFELVQDMQENVNMERVVFKILRRLCSILHADRCSLFMYRQRNGVAELATRLFSVQPDSVLEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVQDVMECPHFSSFADELTDYVTRNILATPIMNGKDVVAVIMAVNKLDGPCFTSEDEDVFLKYLNFGTLNLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCDRYSVGLLDMTKEKEFFDVWPVLMGEAQAYSGPRTPDGREILFYKVIDYI... | entrainment of circadian clock by photoperiod retina development in camera-type eye signal transduction visual perception photoreceptor disc membrane; photoreceptor outer segment membrane 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity metal ion binding Bos taurus 3D-struc... |
detection of light stimulus entrainment of circadian clock by photoperiod retina development in camera-type eye retinal cell apoptotic process signal transduction visual perception | photoreceptor outer segment; photoreceptor outer segment membrane; plasma membrane | 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity metal ion binding | Mus musculus | Acetylation Alternative splicing Cell projection cGMP Hydrolase Lipoprotein Magnesium Manganese Membrane Metal-binding Prenylation Reference proteome Repeat Sensory transduction Vision Zinc | MSLSEEQVRS | MSLSEEQVRSFLDGNPTFAHQYFGKKLSPENVAGACEDGWLADCGSLRELCQVEESAALFELVQDMQESVNMERVVFKILRRLCTILHADRCSLFMYRQRNGIAELATRLFSVQPDSLLEDCLVPPDSEIVFPLDIGIVGHVAQTKKMINVQDVAECPHFSSFADELTDYVTKNILSTPIMNGKDVVAVIMAVNKLDGPCFTSEDEDVFTKYLNFATLNLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCERYSVGLLDMTKEKEFFDVWPVLMGEAQPYSGPRTPDGREIVFYKVIDYI... | detection of light stimulus entrainment of circadian clock by photoperiod retina development in camera-type eye retinal cell apoptotic process signal transduction visual perception photoreceptor outer segment; photoreceptor outer segment membrane; plasma membrane 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic... |
daunorubicin metabolic process doxorubicin metabolic process hippocampus development progesterone metabolic process prostaglandin metabolic process steroid metabolic process | cytosol | alditol:NADP+ 1-oxidoreductase activity androsterone dehydrogenase (B-specific) activity androsterone dehydrogenase activity bile acid binding ketosteroid monooxygenase activity steroid dehydrogenase activity | Rattus norvegicus | 3D-structure Cytoplasm Direct protein sequencing NAD NADP Oxidoreductase Reference proteome | MDSISLRVAL | MDSISLRVALNDGNFIPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQAIRSKIEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQPGDIFFPRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLKYKPVCNQVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKSPVLLDDPVLCAIAKKYKQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEFQLASEDMKALDGLNRNFRYNNAKYFDDHPNHPFT... | daunorubicin metabolic process doxorubicin metabolic process hippocampus development progesterone metabolic process prostaglandin metabolic process steroid metabolic process cytosol alditol:NADP+ 1-oxidoreductase activity androsterone dehydrogenase (B-specific) activity androsterone dehydrogenase activity bile acid bin... |
negative regulation of insulin receptor signaling pathway protein dephosphorylation | cytoplasm; nucleus; plasma membrane | protein tyrosine phosphatase activity transmembrane receptor protein tyrosine phosphatase activity | Homo sapiens | 3D-structure Alternative initiation Alternative promoter usage Cell membrane Cytoplasm Glycoprotein Hydrolase Membrane Phosphoprotein Protein phosphatase Reference proteome Repeat Signal Transmembrane Transmembrane helix | MEPLCPLLLV | MEPLCPLLLVGFSLPLARALRGNETTADSNETTTTSGPPDPGASQPLLAWLLLPLLLLLLVLLLAAYFFRFRKQRKAVVSTSDKKMPNGILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSADDCKQFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPDQGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPDGCKAPRLVSQLHFTSWPDFGVPFTPIGMLKFLKKV... | negative regulation of insulin receptor signaling pathway protein dephosphorylation cytoplasm; nucleus; plasma membrane protein tyrosine phosphatase activity transmembrane receptor protein tyrosine phosphatase activity Homo sapiens 3D-structure Alternative initiation Alternative promoter usage Cell membrane Cytoplasm G... |
chitin catabolic process polysaccharide catabolic process | vacuole | chitinase activity lysozyme activity | Hevea brasiliensis | 3D-structure Carbohydrate metabolism Chitin degradation Direct protein sequencing Disulfide bond Glycosidase Hydrolase Multifunctional enzyme Polysaccharide degradation Signal Vacuole | MAKRTQAILL | MAKRTQAILLLLLAISLIMSSSHVDGGGIAIYWGQNGNEGTLTQTCSTRKYSYVNIAFLNKFGNGQTPQINLAGHCNPAAGGCTIVSNGIRSCQIQGIKVMLSLGGGIGSYTLASQADAKNVADYLWNNFLGGKSSSRPLGDAVLDGIDFDIEHGSTLYWDDLARYLSAYSKQGKKVYLTAAPQCPFPDRYLGTALNTGLFDYVWVQFYNNPPCQYSSGNINNIINSWNRWTTSINAGKIFLGLPAAPEAAGSGYVPPDVLISRILPEIKKSPKYGGVMLWSKFYDDKNGYSSSILDSVLFLHSEECMTVL | chitin catabolic process polysaccharide catabolic process vacuole chitinase activity lysozyme activity Hevea brasiliensis 3D-structure Carbohydrate metabolism Chitin degradation Direct protein sequencing Disulfide bond Glycosidase Hydrolase Multifunctional enzyme Polysaccharide degradation Signal Vacuole MAKRTQAILL MA... |
activation of innate immune response cellular hyperosmotic salinity response cellular response to gamma radiation cellular response to X-ray DNA damage response double-strand break repair double-strand break repair via classical nonhomologous end joining double-strand break repair via nonhomologous end joining innate i... | chromosome; cytoplasm; DNA-dependent protein kinase complex; DNA-dependent protein kinase-DNA ligase 4 complex; Ku70:Ku80 complex; nonhomologous end joining complex; nucleolus; nucleoplasm; nucleus; protein-containing complex; protein-DNA complex; transcription regulator complex | 5'-deoxyribose-5-phosphate lyase activity ATP binding ATP hydrolysis activity ATP-dependent activity, acting on DNA cyclin binding damaged DNA binding DNA helicase activity double-stranded DNA binding protein-containing complex binding scaffold protein binding telomeric DNA binding transcription cis-regulatory region b... | Mus musculus | Acetylation Activator ADP-ribosylation ATP-binding Chromosome DNA damage DNA recombination DNA repair DNA-binding Helicase Hydrolase Immunity Innate immunity Isopeptide bond Lyase Multifunctional enzyme Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MSEWESYYKT | MSEWESYYKTEGEEEEEEEESPDTGGEYKYSGRDSLIFLVDASRAMFESQGEDELTPFDMSIQCIQSVYTSKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQDLDNPGAKRVLELDQFKGQQGKKHFRDTVGHGSDYSLSEVLWVCANLFSDVQLKMSHKRIMLFTNEDDPHGRDSAKASRARTKASDLRDTGIFLDLMHLKKPGGFDVSVFYRDIITTAEDEDLGVHFEESSKLEDLLRKVRAKETKKRVLSRLKFKLGEDVVLMVGIYNLVQKANKPFPVRLYRETNEPVKTKTRTFNVNTGSLLLPSDTKRSLTY... | activation of innate immune response cellular hyperosmotic salinity response cellular response to gamma radiation cellular response to X-ray DNA damage response double-strand break repair double-strand break repair via classical nonhomologous end joining double-strand break repair via nonhomologous end joining innate i... |
DNA-templated transcription initiation intracellular iron ion homeostasis iron ion transport regulation of DNA-templated transcription regulation of DNA-templated transcription initiation | cytosolic DNA-directed RNA polymerase complex | bacterial-type RNA polymerase core enzyme binding core promoter sequence-specific DNA binding sigma factor activity | Escherichia coli | Direct protein sequencing DNA-binding Ion transport Iron Iron transport Reference proteome Sigma factor Transcription Transcription regulation Transport | MSDRATTTAS | MSDRATTTASLTFESLYGTHHGWLKSWLTRKLQSAFDADDIAQDTFLRVMVSETLSTIRDPRSFLCTIAKRVMVDLFRRNALEKAYLEMLALMPEGGAPSPEERESQLETLQLLDSMLDGLNGKTREAFLLSQLDGLTYSEIAHKLGVSISSVKKYVAKAVEHCLLFRLEYGL | DNA-templated transcription initiation intracellular iron ion homeostasis iron ion transport regulation of DNA-templated transcription regulation of DNA-templated transcription initiation cytosolic DNA-directed RNA polymerase complex bacterial-type RNA polymerase core enzyme binding core promoter sequence-specific DNA ... |
keratinization keratinocyte differentiation peptide cross-linking | cornified envelope; cytoplasm; cytosol; nucleoplasm | structural constituent of cytoskeleton structural constituent of skin epidermis | Homo sapiens | Cytoplasm Direct protein sequencing Disulfide bond Ichthyosis Isopeptide bond Keratinization Nucleus Palmoplantar keratoderma Reference proteome Repeat | MSYQKKQPTP | MSYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVPICHQTQQKQAPTWPSK | keratinization keratinocyte differentiation peptide cross-linking cornified envelope; cytoplasm; cytosol; nucleoplasm structural constituent of cytoskeleton structural constituent of skin epidermis Homo sapiens Cytoplasm Direct protein sequencing Disulfide bond Ichthyosis Isopeptide bond Keratinization Nucleus Palmopla... |
binding of sperm to zona pellucida blastocyst formation egg coat formation humoral immune response mediated by circulating immunoglobulin negative regulation of binding of sperm to zona pellucida negative regulation of DNA-templated transcription oocyte development positive regulation of acrosomal vesicle exocytosis po... | collagen-containing extracellular matrix; egg coat; extracellular space; plasma membrane | carbohydrate binding receptor ligand activity structural constituent of egg coat | Mesocricetus auratus | Cell membrane Cleavage on pair of basic residues Disulfide bond Extracellular matrix Fertilization Glycoprotein Membrane Pyrrolidone carboxylic acid Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix | MGLSYQLLLC | MGLSYQLLLCLLLCGGAKQCCSQPLWLLPGGTPTPGKLTSSVEVECLEAELVVTVSRDLFGTGKLIQPEDLTLGSENCRPLVSVATDVVRFKAQLHECSNRVQVTEDALVYSTVLLHQPRPVPGLSILRTNRADVPIECRYPRQGNVSSHAIRPTWVPFSTTVSSEEKLVFSLRLMEENWNTEKLSPTSHLGEVAYLQAEVQTGSHLPLLLFVDRCVPTPSPDQTASPYHVIVDFHGCLVDGLSESFSAFQVPRPRPETLQFTVDVFHFANSSRNTIYITCHLKVTPANQTPDELNKACSFNRSSKSWSPVEGDAEVCGC... | binding of sperm to zona pellucida blastocyst formation egg coat formation humoral immune response mediated by circulating immunoglobulin negative regulation of binding of sperm to zona pellucida negative regulation of DNA-templated transcription oocyte development positive regulation of acrosomal vesicle exocytosis po... |
iron-sulfur cluster assembly | CIA complex; cytosol; membrane; nucleus | 4 iron, 4 sulfur cluster binding ferredoxin hydrogenase activity iron-sulfur cluster binding metal ion binding | Saccharomyces cerevisiae | 4Fe-4S Cytoplasm Iron Iron-sulfur Metal-binding Nucleus Reference proteome | MSALLSESDL | MSALLSESDLNDFISPALACVKPTQVSGGKKDNVNMNGEYEVSTEPDQLEKVSITLSDCLACSGCITSSEEILLSSQSHSVFLKNWGKLSQQQDKFLVVSVSPQCRLSLAQYYGLTLEAADLCLMNFFQKHFQCKYMVGTEMGRIISISKTVEKIIAHKKQKENTGADRKPLLSAVCPGFLIYTEKTKPQLVPMLLNVKSPQQITGSLIRATFESLAIARESFYHLSLMPCFDKKLEASRPESLDDGIDCVITPREIVTMLQELNLDFKSFLTEDTSLYGRLSPPGWDPRVHWASNLGGTCGGYAYQYVTAVQRLHPGSQ... | iron-sulfur cluster assembly CIA complex; cytosol; membrane; nucleus 4 iron, 4 sulfur cluster binding ferredoxin hydrogenase activity iron-sulfur cluster binding metal ion binding Saccharomyces cerevisiae 4Fe-4S Cytoplasm Iron Iron-sulfur Metal-binding Nucleus Reference proteome MSALLSESDL MSALLSESDLNDFISPALACVKPTQVSG... |
methylation negative regulation of cardiac muscle cell apoptotic process protein modification process S-adenosylhomocysteine metabolic process S-adenosylmethionine metabolic process | basolateral plasma membrane; brush border membrane; cytoplasm; cytosol; extracellular space; perikaryon | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity | Mus musculus | Acetylation Alternative splicing Cytoplasm Direct protein sequencing Methyltransferase Reference proteome S-adenosyl-L-methionine Transferase | MAWKSGGASH | MAWKSGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKSNPYMDSPQSIGFQATISAPHMHAYALELLFDQLHEGAKALDVGSGSGILTACFARMVGNSGKVIGIDHIKELVDDSITNVKKDDPMLLSSGRVRLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGNQMLEQYDKLQDGSVKMKPLMGVIYVPLTDKEKQWSRWK | methylation negative regulation of cardiac muscle cell apoptotic process protein modification process S-adenosylhomocysteine metabolic process S-adenosylmethionine metabolic process basolateral plasma membrane; brush border membrane; cytoplasm; cytosol; extracellular space; perikaryon protein-L-isoaspartate (D-aspartat... |
establishment of protein localization negative regulation of canonical Wnt signaling pathway negative regulation of epithelial cell migration negative regulation of epithelial cell proliferation signal transduction Wnt signaling pathway | cytoplasm; cytosol; lamellipodium; nucleoplasm; nucleus; plasma membrane | signaling receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Cell projection Cytoplasm Membrane Nucleus Phosphoprotein Reference proteome Tumor suppressor Wnt signaling pathway | MNSGVAMKYG | MNSGVAMKYGNDSSAELSELHSAALASLKGDIVELNKRLQQTERERDLLEKKLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSVIAELNKKIDRLQGTTIREEDEYSELRSELSQSQHEVNEDSRSMDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCGRKKSSCSLSVAEVDKHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLAEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQATGPSSPGRLTSTNRPINPSTGELSTSSSSND... | establishment of protein localization negative regulation of canonical Wnt signaling pathway negative regulation of epithelial cell migration negative regulation of epithelial cell proliferation signal transduction Wnt signaling pathway cytoplasm; cytosol; lamellipodium; nucleoplasm; nucleus; plasma membrane signaling ... |
glycogen biosynthetic process starch biosynthetic process | amyloplast; chloroplast | ATP binding glucose-1-phosphate adenylyltransferase activity | Solanum tuberosum | 3D-structure Allosteric enzyme Amyloplast ATP-binding Chloroplast Nucleotide-binding Nucleotidyltransferase Plastid Reference proteome Starch biosynthesis Transferase Transit peptide | MAASIGALKS | MAASIGALKSSPSSNNCINERRNDSTRAVSSRNLSFSSSHLAGDKLMPVSSLRSQGVRFNVRRSPMIVSPKAVSDSQNSQTCLDPDASRSVLGIILGGGAGTRLYPLTKKRAKPAVPLGANYRLIDIPVSNCLNSNISKIYVLTQFNSASLNRHLSRAYASNMGGYKNEGFVEVLAAQQSPENPDWFQGTADAVRQYLWLFEEHTVLEYLILAGDHLYRMDYEKFIQAHRETDADITVAALPMDEKRATAFGLMKIDEEGRIIEFAEKPQGEQLQAMKVDTTILGLDDKRAKEMPFIASMGIYVISKDVMLNLLRDKFPG... | glycogen biosynthetic process starch biosynthetic process amyloplast; chloroplast ATP binding glucose-1-phosphate adenylyltransferase activity Solanum tuberosum 3D-structure Allosteric enzyme Amyloplast ATP-binding Chloroplast Nucleotide-binding Nucleotidyltransferase Plastid Reference proteome Starch biosynthesis Tran... |
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