Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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epidermal growth factor receptor ligand maturation signaling receptor ligand precursor processing | membrane; meprin A complex; plasma membrane | metallodipeptidase activity metalloendopeptidase activity metallopeptidase activity zinc ion binding | Mus musculus | Direct protein sequencing Disulfide bond EGF-like domain Glycoprotein Hydrolase Membrane Metal-binding Metalloprotease Protease Reference proteome Signal Transmembrane Transmembrane helix Zinc Zymogen | MLWIQPACLL | MLWIQPACLLSLIFSAHIAAVSIKHLLNGSDHDTDVGEQKDIFEINLAAGLNLFQGDILLPRTRNAMRDPSSRWKLPIPYILADNLELNAKGAILHAFEMFRLKSCVDFKPYEGESSYIIFQKLSGCWSMIGDQQVGQNISIGEGCDFKATIEHEILHALGFFHEQSRTDRDDYVNIWWDQIITDYEHNFNTYDDNTITDLNTPYDYESLMHYGPFSFNKNESIPTITTKIPEFNTIIGQLPDFSAIDLIRLNRMYNCTATHTLLDHCDFEKTNVCGMIQGTRDDADWAHGDSSQPEQVDHTLVGQCKGAGYFMFFNTSL... | epidermal growth factor receptor ligand maturation signaling receptor ligand precursor processing membrane; meprin A complex; plasma membrane metallodipeptidase activity metalloendopeptidase activity metallopeptidase activity zinc ion binding Mus musculus Direct protein sequencing Disulfide bond EGF-like domain Glycopr... |
inflammatory response proteolysis | extracellular region; membrane; meprin A complex; plasma membrane | identical protein binding metalloendopeptidase activity zinc ion binding | Rattus norvegicus | Cell membrane Direct protein sequencing Disulfide bond EGF-like domain Glycoprotein Hydrolase Inflammatory response Membrane Metal-binding Metalloprotease Protease Reference proteome Secreted Signal Transmembrane Transmembrane helix Zinc Zymogen | MDARHWPWFL | MDARHWPWFLVFATFLLVSGLPAPEKFVKDIDGGIDQDIFDINEDLGLDLFEGDIKLEASGRNSIIGDNYRWPHTIPYVLEDSLEMNAKGVILNAFERYRLKTCIDFKPWSGEENYISVFKGSGCWSSVGNIHAGKQELSIGTNCDRIATVQHEFLHALGFWHEQSRADRDDYITIVWDRILSGKEHNFNIYNDSVSDSLNVPYDYTSVMHYSKTAFQNGTESTIITKISDFEDVIGQRMDFSDYDLLKLNQLYSCTSSLSFMDSCDFELENICGMIQSSQDSADWQRLSQVLSGPENDHSNMGQCKDSGFFMHFNTSTG... | inflammatory response proteolysis extracellular region; membrane; meprin A complex; plasma membrane identical protein binding metalloendopeptidase activity zinc ion binding Rattus norvegicus Cell membrane Direct protein sequencing Disulfide bond EGF-like domain Glycoprotein Hydrolase Inflammatory response Membrane Meta... |
induction of conjugation with cellular fusion pheromone response MAPK cascade phosphorylation | cell division site; cell tip; cytoplasm; division septum; plasma membrane | ATP binding MAP kinase kinase kinase activity protein kinase activity protein serine kinase activity | Schizosaccharomyces pombe | 3D-structure ATP-binding Cell membrane Cytoplasm Kinase Membrane Nucleotide-binding Pheromone response Reference proteome Serine/threonine-protein kinase Transferase | MEYYTSKEVA | MEYYTSKEVAEWLKSIGLEKYIEQFSQNNIEGRHLNHLTLPLLKDLGIENTAKGKQFLKQRDYLREFPRPCILRFIACNGQTRAVQSRGDYQKTLAIALKKFSLEDASKFIVCVSQSSRIKLITEEEFKQICFNSSSPERDRLIIVPKEKPCPSFEDLRRSWEIELAQPAALSSQSSLSPKLSSVLPTSTQKRSVRSNNAKPFESYQRPPSELINSRISDFFPDHQPKLLEKTISNSLRRNLSIRTSQGHNLGNFGQEILPRSSRRARPSELVCPLSSLRISVAEDVNRLPRIDRGFDPPLTVSSTQRISRPPSLQKSIT... | induction of conjugation with cellular fusion pheromone response MAPK cascade phosphorylation cell division site; cell tip; cytoplasm; division septum; plasma membrane ATP binding MAP kinase kinase kinase activity protein kinase activity protein serine kinase activity Schizosaccharomyces pombe 3D-structure ATP-binding... |
glutamate biosynthetic process isocitrate metabolic process tricarboxylic acid cycle | cytosol; mitochondrial intermembrane space; mitochondrial isocitrate dehydrogenase complex (NAD+); mitochondrial matrix; mitochondrial nucleoid; mitochondrion | isocitrate dehydrogenase (NAD+) activity magnesium ion binding NAD binding RNA binding | Saccharomyces cerevisiae | 3D-structure Allosteric enzyme Direct protein sequencing Magnesium Manganese Metal-binding Mitochondrion NAD Oxidoreductase Reference proteome RNA-binding Transit peptide Tricarboxylic acid cycle | MLNRTIAKRT | MLNRTIAKRTLATAAQAERTLPKKYGGRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKQTDHKEGVYEAVESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYAT... | glutamate biosynthetic process isocitrate metabolic process tricarboxylic acid cycle cytosol; mitochondrial intermembrane space; mitochondrial isocitrate dehydrogenase complex (NAD+); mitochondrial matrix; mitochondrial nucleoid; mitochondrion isocitrate dehydrogenase (NAD+) activity magnesium ion binding NAD binding R... |
proteolysis | cytoplasm; extracellular exosome; focal adhesion; nucleus | aminopeptidase activity carboxypeptidase activity manganese ion binding metalloaminopeptidase activity metalloexopeptidase activity peptidase activity | Homo sapiens | Acetylation Alternative initiation Aminopeptidase Cytoplasm Direct protein sequencing Hydrolase Magnesium Manganese Metal-binding Phosphoprotein Protease Reference proteome Zinc | MFLLPLPAAG | MFLLPLPAAGRVVVRRLAVRRFGSRSLSTADMTKGLVLGIYSKEKEDDVPQFTSAGENFDKLLAGKLRETLNISGPPLKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEGKENIRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKMAVSAKLYGSGDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWIEEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMDLMRADMGGAATICSAIVSAA... | proteolysis cytoplasm; extracellular exosome; focal adhesion; nucleus aminopeptidase activity carboxypeptidase activity manganese ion binding metalloaminopeptidase activity metalloexopeptidase activity peptidase activity Homo sapiens Acetylation Alternative initiation Aminopeptidase Cytoplasm Direct protein sequencing ... |
proteolysis | cytoplasm | carboxypeptidase activity manganese ion binding metalloaminopeptidase activity peptidase activity | Sus scrofa | Acetylation Aminopeptidase Cytoplasm Direct protein sequencing Hydrolase Magnesium Manganese Metal-binding Phosphoprotein Protease Reference proteome Zinc | MFLLPLPAAA | MFLLPLPAAARVAVRQLSVRRFWGPGPDAANMTKGLVLGIYSKEKEDDAPQFTSAGENFDKLVSGKLREILNISGPPLKAGKTRTFYGLHEDFSSVVVVGLGKKGAGVDDQENWHEGKENIRAAVAAGCRQIQDLEIPSVEVDPCGDAQAAAEGAVLGLYEYDELKQKKKVVVSAKLHGSGDQEAWQRGVLFASGQNLARHLMETPANEMTPTRFAEVIEKNLKSASSKTDVHIRPKSWIEEQEMGSFLSVAKGSEEPPVFLEIHYKGSPDASDPPLVFVGKGITFDSGGISIKASANMDLMRADMGGAATICSTIVSAA... | proteolysis cytoplasm carboxypeptidase activity manganese ion binding metalloaminopeptidase activity peptidase activity Sus scrofa Acetylation Aminopeptidase Cytoplasm Direct protein sequencing Hydrolase Magnesium Manganese Metal-binding Phosphoprotein Protease Reference proteome Zinc MFLLPLPAAA MFLLPLPAAARVAVRQLSVRRFW... |
insulin processing neurogenesis pancreas development peptide biosynthetic process peptide hormone processing pituitary gland development positive regulation of protein secretion protein autoprocessing protein processing response to axon injury response to calcium ion response to chlorate response to fatty acid response... | axon terminus; dendrite; extracellular space; membrane; neuron projection; neuronal cell body; perikaryon; perinuclear region of cytoplasm; secretory granule; secretory granule lumen; trans-Golgi network; transport vesicle | endopeptidase activity identical protein binding serine-type endopeptidase activity | Rattus norvegicus | Calcium Cleavage on pair of basic residues Cytoplasmic vesicle Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MKQRGWTLQC | MKQRGWTLQCTAFTLFCVWCALNSVKAKRQFVNEWAAEIHGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSALHITKRLSDDDRVIWAEQQYEKERRKRSVPRDSALNLFNDPMWNQQWYLQDTRMTASLPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCD... | insulin processing neurogenesis pancreas development peptide biosynthetic process peptide hormone processing pituitary gland development positive regulation of protein secretion protein autoprocessing protein processing response to axon injury response to calcium ion response to chlorate response to fatty acid response... |
enkephalin processing insulin processing islet amyloid polypeptide processing nervous system development peptide hormone processing protein autoprocessing protein processing proteolysis | dendrite; extracellular space; membrane; neuron projection; neuronal cell body; nucleoplasm; perikaryon; secretory granule; secretory granule lumen; transport vesicle | endopeptidase activity serine-type endopeptidase activity | Rattus norvegicus | Cleavage on pair of basic residues Cytoplasmic vesicle Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Secreted Serine protease Signal Zymogen | MEGGCGSQWK | MEGGCGSQWKAAGLLFCVMVFASAERPVFTNHFLVELHKDGEEEARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKRQLERDPRIKMALQQEGFDRKKRGYRDINEIDINMNDPLFTKQWYLFNTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLAYNYNSDASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAASNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDG... | enkephalin processing insulin processing islet amyloid polypeptide processing nervous system development peptide hormone processing protein autoprocessing protein processing proteolysis dendrite; extracellular space; membrane; neuron projection; neuronal cell body; nucleoplasm; perikaryon; secretory granule; secretory ... |
B-1a B cell differentiation behavioral fear response cell adhesion endothelial cell migration locomotory exploration behavior negative regulation of extracellular matrix disassembly negative regulation of neutrophil chemotaxis positive regulation of cell population proliferation positive regulation of natural killer ce... | apical plasma membrane; cell surface; endocytic vesicle; extracellular region; intercellular canaliculus; lamellipodium; lamellipodium membrane; membrane raft; plasma membrane | aminopeptidase activity chemorepellent activity collagen binding dipeptidyl-peptidase activity identical protein binding peptide binding protease binding protein homodimerization activity serine-type endopeptidase activity serine-type peptidase activity signaling receptor binding virus receptor activity | Mus musculus | Aminopeptidase Cell adhesion Cell junction Cell membrane Cell projection Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Membrane Protease Receptor Reference proteome Secreted Serine protease Signal-anchor Transmembrane Transmembrane helix | MKTPWKVLLG | MKTPWKVLLGLLGVAALVTIITVPIVLLSKDEAAADSRRTYSLADYLKSTFRVKSYSLWWVSDFEYLYKQENNILLLNAEHGNSSIFLENSTFESFGYHSVSPDRLFVLLEYNYVKQWRHSYTASYNIYDVNKRQLITEEKIPNNTQWITWSPEGHKLAYVWKNDIYVKVEPHLPSHRITSTGEENVIYNGITDWVYEEEVFGAYSALWWSPNNTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNIDSLSSSSSAAPIQIPAPASVARGDHYLCDVVWATEERISLQWLRRIQNYSVMA... | B-1a B cell differentiation behavioral fear response cell adhesion endothelial cell migration locomotory exploration behavior negative regulation of extracellular matrix disassembly negative regulation of neutrophil chemotaxis positive regulation of cell population proliferation positive regulation of natural killer ce... |
lung development steroid catabolic process | endoplasmic reticulum membrane; intracellular membrane-bounded organelle; membrane | 11-beta-hydroxysteroid dehydrogenase (NADP+) activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity cortisol dehydrogenase activity NADP binding protein homodimerization activity steroid binding | Homo sapiens | 3D-structure Disease variant Endoplasmic reticulum Glycoprotein Lipid metabolism Membrane NADP Oxidoreductase Reference proteome Signal-anchor Steroid metabolism Transmembrane Transmembrane helix | MAFMKKYLLP | MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK | lung development steroid catabolic process endoplasmic reticulum membrane; intracellular membrane-bounded organelle; membrane 11-beta-hydroxysteroid dehydrogenase (NADP+) activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity cortisol dehydrogenase activity NADP binding protein homodimerization activity steroid ... |
cellular response to oxidative stress heme catabolic process iron-sulfur cluster assembly response to superoxide response to xenobiotic stimulus | cytosol | aconitate hydratase activity FAD binding ferredoxin-NADP+ reductase activity succinate dehydrogenase activity | Escherichia coli | 3D-structure Cytoplasm Direct protein sequencing FAD Flavoprotein NADP Nucleotide-binding Oxidoreductase Reference proteome | MADWVTGKVT | MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPGHMTAEHYW | cellular response to oxidative stress heme catabolic process iron-sulfur cluster assembly response to superoxide response to xenobiotic stimulus cytosol aconitate hydratase activity FAD binding ferredoxin-NADP+ reductase activity succinate dehydrogenase activity Escherichia coli 3D-structure Cytoplasm Direct protein se... |
cellular response to amino acid stimulus cellular response to reactive oxygen species cellular response to UV-A collagen catabolic process extracellular matrix organization innate immune response negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of reactive ox... | cell body; cytosol; dendrite; extracellular matrix; extracellular region; extracellular space; mitochondrion; protein-containing complex | endopeptidase activity metalloendopeptidase activity metallopeptidase activity peptidase activity protein-containing complex binding zinc ion binding | Mus musculus | Calcium Collagen degradation Disulfide bond Extracellular matrix Hydrolase Immunity Innate immunity Metal-binding Metalloprotease Protease Reference proteome Repeat Secreted Signal Zinc Zymogen | MKGLPVLLWL | MKGLPVLLWLCVVVCSSYPLHDSARDDDAGMELLQKYLENYYGLAKDVKQFIKKKDSSLIVKKIQEMQKFLGLEMTGKLDSNTMELMHKPRCGVPDVGGFSTFPGSPKWRKSHITYRIVNYTPDLPRQSVDSAIEKALKVWEEVTPLTFSRISEGEADIMISFAVGEHGDFVPFDGPGTVLAHAYAPGPGINGDAHFDDDERWTEDVTGTNLFLVAAHELGHSLGLYHSAKAEALMYPVYKSSTDLSRFHLSQDDVDGIQSLYGTPTASPDVLVVPTKSNSLEPETSPMCSSTLFFDAVSTLRGEVLFFKDRHFWRKSLR... | cellular response to amino acid stimulus cellular response to reactive oxygen species cellular response to UV-A collagen catabolic process extracellular matrix organization innate immune response negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of reactive ox... |
proteolysis | extracellular region | metal ion binding metalloendopeptidase activity toxin activity | Agkistrodon contortrix contortrix | Direct protein sequencing Disulfide bond Fibrinolytic toxin Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Pharmaceutical Protease Pyrrolidone carboxylic acid Secreted Toxin Zinc | QQRFPQRYVQ | QQRFPQRYVQLVIVADHRMNTKYNGDSDKIRQWVHQIVNTINEIYRPLNIQFTLVGLEIWSNQDLITVTSVSHDTLASFGNWRETDLLRRQRHDNAQLLTAIDFDGDTVGLAYVGGMCQLKHSTGVIQDHSAINLLVALTMAHELGHNLGMNHDGNQCHCGANSCVMAAMLSDQPSKLFSDCSKKDYQTFLTVNNPQCILNKP | proteolysis extracellular region metal ion binding metalloendopeptidase activity toxin activity Agkistrodon contortrix contortrix Direct protein sequencing Disulfide bond Fibrinolytic toxin Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Pharmaceutical Protease Pyrrolidone carboxylic acid Secreted To... |
2'-deoxyribonucleotide biosynthetic process DNA replication nucleobase-containing small molecule interconversion | anaerobic ribonucleoside-triphosphate reductase complex | ATP binding CTP reductase activity dATP binding dGTP binding pyrimidine deoxyribonucleotide binding ribonucleoside-triphosphate reductase activity zinc ion binding | Escherichia coli | Allosteric enzyme ATP-binding Direct protein sequencing Metal-binding Nucleotide-binding Organic radical Oxidoreductase Reference proteome Zinc | MTPHVMKRDG | MTPHVMKRDGCKVPFKSERIKEAILRAAKAAEVDDADYCATVAAVVSEQMQGRNQVDINEIQTAVENQLMSGPYKQLARAYIEYRHDRDIEREKRGRLNQEIRGLVEQTNASLLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIHYHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVTASYNKHRKTAEEWNIPDAEGYANSRTIKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTSWESRLIQESILRNRIAGLGK... | 2'-deoxyribonucleotide biosynthetic process DNA replication nucleobase-containing small molecule interconversion anaerobic ribonucleoside-triphosphate reductase complex ATP binding CTP reductase activity dATP binding dGTP binding pyrimidine deoxyribonucleotide binding ribonucleoside-triphosphate reductase activity zinc... |
cell motility cell-cell adhesion cell-matrix adhesion endothelial cell proliferation endothelium development extracellular exosome assembly glomerular endothelium development glomerular filtration hematopoietic stem cell proliferation hemopoiesis leukocyte migration mesangial cell-matrix adhesion metanephric glomerular... | apical plasma membrane; basal plasma membrane; cytoplasm; external side of plasma membrane; extracellular region; glomerular endothelium fenestra; intercellular bridge; lysosome; perinuclear region of cytoplasm; plasma membrane | carbohydrate binding RNA polymerase II-specific DNA-binding transcription factor binding sulfate binding | Homo sapiens | Alternative splicing Cell adhesion Direct protein sequencing Glycoprotein Membrane Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MLVRRGARAG | MLVRRGARAGPRMPRGWTALCLLSLLPSGFMSLDNNGTATPELPTQGTFSNVSTNVSYQETTTPSTLGSTSLHPVSQHGNEATTNITETTVKFTSTSVITSVYGNTNSSVQSQTSVISTVFTTPANVSTPETTLKPSLSPGNVSDLSTTSTSLATSPTKPYTSSSPILSDIKAEIKCSGIREVKLTQGICLEQNKTSSCAEFKKDRGEGLARVLCGEEQADADAGAQVCSLLLAQSEVRPQCLLLVLANRTEISSKLQLMKKHQSDLKKLGILDFTEQDVASHQSYSQKTLIALVTSGALLAVLGITGYFLMNRRSWSPT... | cell motility cell-cell adhesion cell-matrix adhesion endothelial cell proliferation endothelium development extracellular exosome assembly glomerular endothelium development glomerular filtration hematopoietic stem cell proliferation hemopoiesis leukocyte migration mesangial cell-matrix adhesion metanephric glomerular... |
apoptotic signaling pathway artery smooth muscle contraction B cell proliferation B cell receptor signaling pathway female pregnancy long-term synaptic depression NAD metabolic process negative regulation of apoptotic process negative regulation of bone resorption negative regulation of DNA-templated transcription nega... | basolateral plasma membrane; cell surface; extracellular exosome; membrane; plasma membrane | identical protein binding NAD(P)+ nucleosidase activity NAD+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating phosphorus-oxygen lyase activity transferase activity | Homo sapiens | 3D-structure Alternative splicing Diabetes mellitus Disulfide bond Glycoprotein Hydrolase Membrane NAD NADP Receptor Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MANCEFSPVS | MANCEFSPVSGDKPCCRLSRRAQLCLGVSILVLILVVVLAVVVPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI | apoptotic signaling pathway artery smooth muscle contraction B cell proliferation B cell receptor signaling pathway female pregnancy long-term synaptic depression NAD metabolic process negative regulation of apoptotic process negative regulation of bone resorption negative regulation of DNA-templated transcription nega... |
cellular response to mechanical stimulus negative regulation of cell population proliferation positive regulation of apoptotic process positive regulation of TRAIL production positive regulation of tumor necrosis factor production signal transduction | cytoplasm; extracellular exosome; nucleoplasm; plasma membrane | transmembrane signaling receptor activity | Homo sapiens | 3D-structure Alternative initiation Alternative splicing Cell membrane Cytoplasm Disulfide bond Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MRVLLAALGL | MRVLLAALGLLFLGALRAFPQDRPFEDTCHGNPSHYYDKAVRRCCYRCPMGLFPTQQCPQRPTDCRKQCEPDYYLDEADRCTACVTCSRDDLVEKTPCAWNSSRVCECRPGMFCSTSAVNSCARCFFHSVCPAGMIVKFPGTAQKNTVCEPASPGVSPACASPENCKEPSSGTIPQAKPTPVSPATSSASTMPVRGGTRLAQEAASKLTRAPDSPSSVGRPSSDPGLSPTQPCPEGSGDCRKQCEPDYYLDEAGRCTACVSCSRDDLVEKTPCAWNSSRTCECRPGMICATSATNSCARCVPYPICAAETVTKPQDMAEK... | cellular response to mechanical stimulus negative regulation of cell population proliferation positive regulation of apoptotic process positive regulation of TRAIL production positive regulation of tumor necrosis factor production signal transduction cytoplasm; extracellular exosome; nucleoplasm; plasma membrane transm... |
sucrose metabolic process | membrane; vacuolar lumen | beta-fructofuranosidase activity | Vigna radiata var. radiata | Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Membrane Reference proteome Signal-anchor Transmembrane Transmembrane helix Vacuole Zymogen | MEHHKPLLPT | MEHHKPLLPTSSHAAPTSSTRKDLLFVLCGLLFLSSLVAYGGYRASGVPHAHLSSPTSNHQQDHQSPTSLPSSKWYPVSRGVSSGVSEKSSNLLFAGEGGASEAFPWDNSMLSWQRTSFHFQPEKNWMNDPNGPMYYKGWYHFFYQYNPNGAVWGDIVWGHAVSRDMIHWLHLPLAMVADQWYDKQGVWTGSATILPNGEIIMLYTGSTNESVQVQNLAYPADPSDPLLLDWIKHTGNPVLVPPPGIGAKDFRDPTTAWLTSEGKWRITIGSKLNKTGIALVYDTEDFKTYELKEGLLRAVPGTGMWECVDFFPVSKKNG... | sucrose metabolic process membrane; vacuolar lumen beta-fructofuranosidase activity Vigna radiata var. radiata Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Membrane Reference proteome Signal-anchor Transmembrane Transmembrane helix Vacuole Zymogen MEHHKPLLPT MEHHKPLLPTSSHAAPTSSTRKDLLFVLC... |
adaptive immune response antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | cell surface; cytosol; endosome membrane; external side of plasma membrane; extracellular space; Golgi apparatus; intracellular membrane-bounded organelle; lysosomal membrane; membrane; plasma membrane | endogenous lipid antigen binding exogenous lipid antigen binding lipopeptide binding | Homo sapiens | 3D-structure Adaptive immunity Alternative splicing Cell membrane Disulfide bond Endosome Glycoprotein Immunity Immunoglobulin domain Lysosome Membrane Reference proteome Signal Transmembrane Transmembrane helix | MLLLPFQLLA | MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLLLCLA... | adaptive immune response antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity cell surface; cytosol; endosome membrane; external side of plasma memb... |
adaptive immune response antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity T cell activation involved in immune response | endoplasmic reticulum; endosome membrane; external side of plasma membrane; extracellular space; Golgi apparatus; intracellular membrane-bounded organelle; lysosome; plasma membrane | endogenous lipid antigen binding exogenous lipid antigen binding glycolipid binding lipopeptide binding | Homo sapiens | 3D-structure Adaptive immunity Cell membrane Disulfide bond Endosome Glycoprotein Immunity Immunoglobulin domain Lipid-binding Lysosome Membrane Reference proteome Signal Transmembrane Transmembrane helix | MLFLQFLLLA | MLFLQFLLLALLLPGGDNADASQEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDSESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYEGVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWMRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIILYWGHHFSMNWIALVVIVPLVILIVLV... | adaptive immune response antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity T cell activation involved in immune response endoplasmic reticulum; e... |
cell redox homeostasis cysteine export across plasma membrane glutathione transmembrane transport transmembrane transport | ATP-binding cassette (ABC) transporter complex; membrane; plasma membrane | ABC-type transporter activity ATP binding ATP hydrolysis activity ATPase-coupled lipid transmembrane transporter activity ATPase-coupled transmembrane transporter activity | Escherichia coli | 3D-structure Amino-acid transport ATP-binding Cell inner membrane Cell membrane Membrane Nucleotide-binding Reference proteome Translocase Transmembrane Transmembrane helix Transport | MNKSRQKELT | MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGA... | cell redox homeostasis cysteine export across plasma membrane glutathione transmembrane transport transmembrane transport ATP-binding cassette (ABC) transporter complex; membrane; plasma membrane ABC-type transporter activity ATP binding ATP hydrolysis activity ATPase-coupled lipid transmembrane transporter activity AT... |
amino sugar metabolic process cell wall macromolecule catabolic process chitin catabolic process defense response to fungus polysaccharide catabolic process | extracellular region | chitin binding chitinase activity endochitinase activity | Zea mays | 3D-structure Allergen Carbohydrate metabolism Chitin degradation Chitin-binding Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Plant defense Polysaccharide degradation Reference proteome Secreted Signal | MANAPRILAL | MANAPRILALGLLALLCAAAGPAAAQNCGCQPNFCCSKFGYCGTTDAYCGDGCQSGPCRSGGGGGGGGGGGGGGSGGANVANVVTDAFFNGIKNQAGSGCEGKNFYTRSAFLSAVNAYPGFAHGGTEVEGKREIAAFFAHVTHETGHFCYISEINKSNAYCDASNRQWPCAAGQKYYGRGPLQISWNYNYGPAGRDIGFNGLADPNRVAQDAVIAFKTALWFWMNNVHRVMPQGFGATIRAINGALECNGNNPAQMNARVGYYKQYCQQLRVDPGPNLTC | amino sugar metabolic process cell wall macromolecule catabolic process chitin catabolic process defense response to fungus polysaccharide catabolic process extracellular region chitin binding chitinase activity endochitinase activity Zea mays 3D-structure Allergen Carbohydrate metabolism Chitin degradation Chitin-bind... |
cell wall organization chitin catabolic process polysaccharide catabolic process septum digestion after cytokinesis | cellular bud neck; endoplasmic reticulum; extracellular region; fungal-type cell wall; fungal-type vacuole; nuclear envelope | chitin binding chitinase activity endochitinase activity | Saccharomyces cerevisiae | 3D-structure Carbohydrate metabolism Cell wall Cell wall biogenesis/degradation Chitin degradation Chitin-binding Direct protein sequencing Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Reference proteome Secreted Signal | MSLLYIILLF | MSLLYIILLFTQFLLLPTDAFDRSANTNIAVYWGQNSAGTQESLATYCESSDADIFLLSFLNQFPTLGLNFANACSDTFSDGLLHCTQIAEDIETCQSLGKKVLLSLGGASGSYLFSDDSQAETFAQTLWDTFGEGTGASERPFDSAVVDGFDFDIENNNEVGYSALATKLRTLFAEGTKQYYLSAAPQCPYPDASVGDLLENADIDFAFIQFYNNYCSVSGQFNWDTWLTYAQTVSPNKNIKLFLGLPGSASAAGSGYISDTSLLESTIADIASSSSFGGIALWDASQAFSNELNGEPYVEILKNLLTSASQTATTTVA... | cell wall organization chitin catabolic process polysaccharide catabolic process septum digestion after cytokinesis cellular bud neck; endoplasmic reticulum; extracellular region; fungal-type cell wall; fungal-type vacuole; nuclear envelope chitin binding chitinase activity endochitinase activity Saccharomyces cerevisi... |
cell-cell signaling cellular response to dexamethasone stimulus cellular response to glucagon stimulus cellular response to oxidative stress decidualization epididymis development gap junction assembly gap junction-mediated intercellular transport inner ear development response to estradiol response to human chorionic ... | astrocyte projection; cell body; connexin complex; endoplasmic reticulum-Golgi intermediate compartment; gap junction; lateral plasma membrane; perinuclear region of cytoplasm; plasma membrane | calcium ion binding gap junction channel activity gap junction channel activity involved in cell communication by electrical coupling identical protein binding | Homo sapiens | 3D-structure Calcium Cell junction Cell membrane Deafness Disease variant Disulfide bond Ectodermal dysplasia Gap junction Hearing Ichthyosis Membrane Metal-binding Non-syndromic deafness Palmoplantar keratoderma Reference proteome Transmembrane Transmembrane helix | MDWGTLQTIL | MDWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGEIKSEFKDIEEIKTQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRYCSGKSKKPV | cell-cell signaling cellular response to dexamethasone stimulus cellular response to glucagon stimulus cellular response to oxidative stress decidualization epididymis development gap junction assembly gap junction-mediated intercellular transport inner ear development response to estradiol response to human chorionic ... |
intracellular sequestering of iron ion iron ion transport | chloroplast; cytoplasm | ferric iron binding ferrous iron binding ferroxidase activity | Zea mays | Chloroplast Direct protein sequencing Iron Iron storage Metal-binding Oxidoreductase Plastid Reference proteome Transit peptide | MMLRVSPSPA | MMLRVSPSPAAAVPTQLSGAPATPAPVVRVAAPRGVASPSAGAACRAAGKGKEVLSGVVFQPFEEIKGELALVPQSPDKSLARHKFVDDCEAALNEQINVEYNASYAYHSLFAYFDRDNVALKGFAKFFKESSDEEREHAEKLMEYQNKRGGRVRLQSIVTPLTEFDHPEKGDALYAMELALALEKLVNEKLHNLHGVATRCNDPQLTDFIESEFLEEQGEAINKISKYVAQLRRVGKGHGVWHFDQMLLEEEA | intracellular sequestering of iron ion iron ion transport chloroplast; cytoplasm ferric iron binding ferrous iron binding ferroxidase activity Zea mays Chloroplast Direct protein sequencing Iron Iron storage Metal-binding Oxidoreductase Plastid Reference proteome Transit peptide MMLRVSPSPA MMLRVSPSPAAAVPTQLSGAPATPAPVVR... |
DNA-templated transcription initiation mRNA transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of transcription initiation by RNA polymerase II RNA polymerase II preinitiation complex assembly transcription by RNA polymerase II transcription by RNA polymerase III | chromatin; cytoplasm; euchromatin; female germ cell nucleus; female pronucleus; male germ cell nucleus; male pronucleus; nucleoplasm; nucleus; pronucleus; protein-containing complex; RNA polymerase I transcription regulator complex; RNA polymerase transcription factor SL1 complex; transcription factor TFIIA complex; tr... | aryl hydrocarbon receptor binding core promoter sequence-specific DNA binding DNA binding DNA-binding transcription factor binding enzyme binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II general transcription in... | Mus musculus | DNA-binding Nucleus Reference proteome Repeat Transcription Transcription regulation | MDQNNSLPPY | MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQAVATAAASVQQSTSQQPTQGASGQTPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT | DNA-templated transcription initiation mRNA transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of transcription initiation by RNA polymerase II RNA polymerase II preinitiation complex assembly transcription by RNA polymerase II transcription by RNA polymerase III c... |
mRNA transcription by RNA polymerase II regulation of DNA binding transcription initiation at RNA polymerase II promoter transcription preinitiation complex assembly transcriptional start site selection at RNA polymerase II promoter | nucleus; transcription preinitiation complex | acetyltransferase activity metal ion binding RNA polymerase II general transcription initiation factor activity TBP-class protein binding | Drosophila melanogaster | Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger | MASTSRLDNN | MASTSRLDNNKVCCYAHPESPLIEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNEKSGVDPSRVGGPENPLLSGGDLSTIIGPGTGSASFDAFGAPKYQNRRTMSSSDRSLISAFKEISSMADRINLPKTIVDRANNLFKQVHDGKNLKGRSNDAKASACLYIACRQEGVPRTFKEICAVSKISKKEIGRCFKLTLKALETSVDLITTADFMCRFCANLDLPNMVQRAATHIAKKAVEMDIVPGRSPISVAAAAIYMASQASEHKRSQKEIGDIAGVADVTIRQSYKLMYPHAAKLFPEDFKFTTPIDQLPQM | mRNA transcription by RNA polymerase II regulation of DNA binding transcription initiation at RNA polymerase II promoter transcription preinitiation complex assembly transcriptional start site selection at RNA polymerase II promoter nucleus; transcription preinitiation complex acetyltransferase activity metal ion bindi... |
positive regulation of transcription regulatory region DNA binding RNA polymerase II preinitiation complex assembly transcription initiation at RNA polymerase II promoter transcription open complex formation at RNA polymerase II promoter transcriptional start site selection at RNA polymerase II promoter | nucleus; transcription preinitiation complex | metal ion binding RNA polymerase II complex binding RNA polymerase II complex recruiting activity RNA polymerase II general transcription initiation factor activity TBP-class protein binding | Saccharomyces cerevisiae | 3D-structure Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger | MMTRESIDKR | MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTRSEWRTFSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMDKKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIPRFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQTLQVTEGTIKSGYKILYEHR... | positive regulation of transcription regulatory region DNA binding RNA polymerase II preinitiation complex assembly transcription initiation at RNA polymerase II promoter transcription open complex formation at RNA polymerase II promoter transcriptional start site selection at RNA polymerase II promoter nucleus; transc... |
DNA-templated transcription initiation DNA-templated transcription open complex formation regulation of transcription by RNA polymerase III RNA polymerase III preinitiation complex assembly transcription by RNA polymerase III | nucleoplasm; nucleus; transcription factor TFIIIB complex; transcription preinitiation complex | DNA binding metal ion binding RNA polymerase III core binding RNA polymerase III general transcription initiation factor activity RNA polymerase III type 3 promoter sequence-specific DNA binding TBP-class protein binding TFIIIC-class transcription factor complex binding | Saccharomyces cerevisiae | 3D-structure Activator Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger | MPVCKNCHGT | MPVCKNCHGTEFERDLSNANNDLVCKACGVVSEDNPIVSEVTFGETSAGAAVVQGSFIGAGQSHAAFGGSSALESREATLNNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCLYVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVKKLHITELPLADPSLFIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILLACRMNNLRRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKLSVQKFRENDVEDGEARPPSFVKNRKKERKIKDSLDKEEMFQTSEEALNKN... | DNA-templated transcription initiation DNA-templated transcription open complex formation regulation of transcription by RNA polymerase III RNA polymerase III preinitiation complex assembly transcription by RNA polymerase III nucleoplasm; nucleus; transcription factor TFIIIB complex; transcription preinitiation complex... |
protein dephosphorylation | cytoplasm; cytoplasmic side of plasma membrane; cytoskeleton; cytosol; nucleoplasm | cytoskeletal protein binding glutamate receptor binding non-membrane spanning protein tyrosine phosphatase activity protein tyrosine phosphatase activity | Homo sapiens | 3D-structure Cell membrane Cytoplasm Cytoskeleton Hydrolase Membrane Phosphoprotein Protein phosphatase Reference proteome | MTSRFRLPAG | MTSRFRLPAGRTYNVRASELARDRQHTEVVCNILLLDNTVQAFKVNKHDQGQVLLDVVFKHLDLTEQDYFGLQLADDSTDNPRWLDPNKPIRKQLKRGSPYSLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLPCPSNTAALLASFAVQSELGDYDQSENLSGYLSDYSFIPNQPQDFEKEIAKLHQQHIGLSPAEAEFNYLNTARTLELYGVEFHYARDQSNNEIMIGVMSGGILIYKNRVRMNTFPWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKNLWKACVEHHTFFRLDRPLPPQKNF... | protein dephosphorylation cytoplasm; cytoplasmic side of plasma membrane; cytoskeleton; cytosol; nucleoplasm cytoskeletal protein binding glutamate receptor binding non-membrane spanning protein tyrosine phosphatase activity protein tyrosine phosphatase activity Homo sapiens 3D-structure Cell membrane Cytoplasm Cytoske... |
transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter transcription open complex formation at RNA polymerase II promoter | cytosol; nucleoplasm; nucleus; transcription factor TFIID complex; transcription factor TFIIE complex | metal ion binding molecular adaptor activity RNA polymerase II general transcription initiation factor activity | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Host-virus interaction Metal-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MADPDVLTEV | MADPDVLTEVPAALKRLAKYVIRGFYGIEHALALDILIRNSCVKEEDMLELLKFDRKQLRSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERDSTNRASFKCPVCSSTFTDLEANQLFDPMTGTFRCTFCHTEVEEDESAMPKKDARTLLARFNEQIEPIYALLRETEDVNLAYEILEPEPTEIPALKQSKDHAATTAGAASLAGGHHREAWATKGPSYEDLYTQNVVINMDDQEDLHRASLEGKSAKERPIWLRESTVQGAYGSEDMKEGGIDMDAFQEREEGHAGPDDNEE... | transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter transcription open complex formation at RNA polymerase II promoter cytosol; nucleoplasm; nucleus; transcription factor TFIID complex; transcription factor TFIIE complex metal ion binding molecular adaptor activity RNA polymerase I... |
transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter | cytosol; nucleoplasm; transcription factor TFIID complex; transcription factor TFIIE complex | DNA binding RNA binding RNA polymerase II general transcription initiation factor activity | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Disease variant DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MDPSLLRERE | MDPSLLRERELFKKRALSTPVVEKRSASSESSSSSSKKKKTKVEHGGSSGSKQNSDHSNGSFNLKALSGSSGYKFGVLAKIVNYMKTRHQRGDTHPLTLDEILDETQHLDIGLKQKQWLMTEALVNNPKIEVIDGKYAFKPKYNVRDKKALLRLLDQHDQRGLGGILLEDIEEALPNSQKAVKALGDQILFVNRPDKKKILFFNDKSCQFSVDEEFQKLWRSVTVDSMDEEKIEEYLKRQGISSMQESGPKKVAPIQRRKKPASQKKRRFKTHNEHLAGVLKDYSDITSSK | transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter cytosol; nucleoplasm; transcription factor TFIID complex; transcription factor TFIIE complex DNA binding RNA binding RNA polymerase II general transcription initiation factor activity Homo sapiens 3D-structure Acetylation Direct p... |
angiotensin-activated signaling pathway blood vessel development cellular response to dexamethasone stimulus drinking behavior G protein-coupled receptor signaling pathway inflammatory response kidney development maintenance of blood vessel diameter homeostasis by renin-angiotensin neuron apoptotic process positive reg... | plasma membrane | angiotensin type I receptor activity angiotensin type II receptor activity | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MTLNSSTEDG | MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYI... | angiotensin-activated signaling pathway blood vessel development cellular response to dexamethasone stimulus drinking behavior G protein-coupled receptor signaling pathway inflammatory response kidney development maintenance of blood vessel diameter homeostasis by renin-angiotensin neuron apoptotic process positive reg... |
calcium ion-regulated exocytosis of neurotransmitter calcium-dependent activation of synaptic vesicle fusion cell differentiation cellular response to calcium ion positive regulation of dendrite extension regulation of calcium ion-dependent exocytosis regulation of dopamine secretion synaptic vesicle endocytosis synapt... | axon; chromaffin granule membrane; dense core granule; exocytic vesicle; neuromuscular junction; plasma membrane; synaptic vesicle membrane; terminal bouton | calcium ion binding calcium-dependent phospholipid binding clathrin binding inositol 1,3,4,5 tetrakisphosphate binding phosphatidylserine binding syntaxin binding | Rattus norvegicus | 3D-structure Calcium Cytoplasm Cytoplasmic vesicle Differentiation Glycoprotein Membrane Metal-binding Phosphoprotein Reference proteome Repeat Synapse Transmembrane Transmembrane helix | MRNIFKRNQE | MRNIFKRNQEPIVAPATTTATMPLAPAAPADNSTESTGTGESQEDMFAKLKDKFFNEINKIPLPPWALIAMAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQN... | calcium ion-regulated exocytosis of neurotransmitter calcium-dependent activation of synaptic vesicle fusion cell differentiation cellular response to calcium ion positive regulation of dendrite extension regulation of calcium ion-dependent exocytosis regulation of dopamine secretion synaptic vesicle endocytosis synapt... |
isoleucine biosynthetic process valine biosynthetic process | cytosol | ketol-acid reductoisomerase activity magnesium ion binding NADP binding | Synechocystis sp. | Amino-acid biosynthesis Branched-chain amino acid biosynthesis Direct protein sequencing Magnesium Metal-binding NADP Oxidoreductase Reference proteome | MARMYYDQDA | MARMYYDQDANLDLLAGKTVAIIGYGSQGHAHALNLKDSGVNVVVGLYSGSKSVAKAEGAGLKVLSVAEAAKAADLIMILLPDEVQKTVYEAEIAPNLVAGNVLLFAHGFNINFAQIVPPADVDVVMAAPKGPGHLVRRTYEQGQGVPALFAVYQDASGQARDYAMAYAKGIGGTRAGILETTFREETETDLFGEQVVLCGGLTALIKAGFDTLVEAGYQPELAYFECLHEVKLIVDLIVEGGLAKMRDSISNTAEYGDLTRGPRIVTEETKAEMRQILDEIQSGQFAREFVLENQAGKPGFTAMRRRESEELIEEVGKD... | isoleucine biosynthetic process valine biosynthetic process cytosol ketol-acid reductoisomerase activity magnesium ion binding NADP binding Synechocystis sp. Amino-acid biosynthesis Branched-chain amino acid biosynthesis Direct protein sequencing Magnesium Metal-binding NADP Oxidoreductase Reference proteome MARMYYDQDA... |
cytokine precursor processing | endosome membrane; extracellular region; Golgi apparatus; plasma membrane | metal ion binding serine-type endopeptidase activity | Xenopus laevis | Cell membrane Cleavage on pair of basic residues Disulfide bond Endosome Glycoprotein Golgi apparatus Hydrolase Membrane Metal-binding Protease Reference proteome Repeat Secreted Serine protease Signal Transmembrane Transmembrane helix Zymogen | MDLSPSLLLM | MDLSPSLLLMLWTLLSVLVEEITGQKVYTNTWAAHISGGSAEADRLCKKYGFINHGLIFEDHYHFSHRAVMKRSLTPKRTRQVLLKREPQVHWLEQQVAKKRKKRDIYTDPTDPKFMQQWYLLDTNRHDLHVKEAWEQGFTGKGIVVSILDDGIEKNHPDLQANYDPAASYDVNDQDPDPQPRYTQLNDNRHGTRCAGEVAAVANNGICGVGIAYNANIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPAKLAEEAFYRGVTQGRGGLGSIYVWASGNGGREHDSCNCDGYTNSIYTLSISSTTQ... | cytokine precursor processing endosome membrane; extracellular region; Golgi apparatus; plasma membrane metal ion binding serine-type endopeptidase activity Xenopus laevis Cell membrane Cleavage on pair of basic residues Disulfide bond Endosome Glycoprotein Golgi apparatus Hydrolase Membrane Metal-binding Protease Refe... |
cell-cell signaling insulin processing neurogenesis pancreas development peptide biosynthetic process peptide hormone processing pituitary gland development positive regulation of protein secretion protein autoprocessing proteolysis response to axon injury response to calcium ion response to chlorate response to fatty ... | axon terminus; dendrite; extracellular space; membrane; neuron projection; perikaryon; perinuclear region of cytoplasm; secretory granule lumen; trans-Golgi network; transport vesicle | identical protein binding serine-type endopeptidase activity | Homo sapiens | Alternative splicing Calcium Cleavage on pair of basic residues Cytoplasmic vesicle Disease variant Disulfide bond Glycoprotein Hydrolase Obesity Protease Reference proteome Serine protease Signal Zymogen | MERRAWSLQC | MERRAWSLQCTAFVLFCAWCALNSAKAKRQFVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCD... | cell-cell signaling insulin processing neurogenesis pancreas development peptide biosynthetic process peptide hormone processing pituitary gland development positive regulation of protein secretion protein autoprocessing proteolysis response to axon injury response to calcium ion response to chlorate response to fatty ... |
acrosome reaction binding of sperm to zona pellucida fertilization peptide hormone processing protein processing reproductive process sperm capacitation | acrosomal membrane; acrosomal vesicle; endoplasmic reticulum lumen; membrane; trans-Golgi network | serine-type endopeptidase activity | Mus musculus | Alternative splicing Cleavage on pair of basic residues Cytoplasmic vesicle Glycoprotein Hydrolase Membrane Protease Reference proteome Serine protease Signal Zymogen | MRPSQTELWL | MRPSQTELWLGLTLTLALLAVRWASAQAPIYVSSWAVRVTKGYQEAERLARKFGFVNLGQIFPDDQYFHLRHRGVAQQSLTPHWGHRLRLKKDPKVRWFEQQTLRRRVKRSLVVPTDPWFSKQWYMNKEIQQDLNILKAWNQGLTGRGVVISILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSATANNGFCGAGVAFNARIGGVRMLDGAITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVG... | acrosome reaction binding of sperm to zona pellucida fertilization peptide hormone processing protein processing reproductive process sperm capacitation acrosomal membrane; acrosomal vesicle; endoplasmic reticulum lumen; membrane; trans-Golgi network serine-type endopeptidase activity Mus musculus Alternative splicing ... |
determination of left/right symmetry glycoprotein metabolic process nerve growth factor production peptide hormone processing plasma lipoprotein particle remodeling protein processing regulation of BMP signaling pathway secretion by cell zygotic determination of anterior/posterior axis, embryo | cell surface; collagen-containing extracellular matrix; endoplasmic reticulum; extracellular region; extracellular space; Golgi lumen; membrane; plasma membrane | endopeptidase activity heparin binding nerve growth factor binding serine-type endopeptidase activity | Homo sapiens | Alternative splicing Calcium Cleavage on pair of basic residues Endoplasmic reticulum Glycoprotein Hydrolase Membrane Protease Reference proteome Repeat Secreted Serine protease Signal Zymogen | MPPRAPPAPG | MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGR... | determination of left/right symmetry glycoprotein metabolic process nerve growth factor production peptide hormone processing plasma lipoprotein particle remodeling protein processing regulation of BMP signaling pathway secretion by cell zygotic determination of anterior/posterior axis, embryo cell surface; collagen-co... |
suppression by virus of host intracellular interferon activity suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity symbiont-mediated disruption of host cell PML body | host cell nucleus; host cell PML body | DNA binding metal ion binding transferase activity | Bovine herpesvirus 1.1 | Activator DNA-binding Early protein Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host IRF3 by virus Inhibition of host mitotic exit by virus Inhibition of host RLR pathway by virus Metal-binding Modulation of host cell cycle by virus Modulation of host ubiquitin pathway by vir... | MAPPAAAPEL | MAPPAAAPELGSCCICLDAITGAARALPCLHAFCLACIRRWLEGRPTCPLCKAPVQSLIHSVASDECFEEIPVGGGPGADGALEPDAAVIWGEDYDAGPIDLTAADGEASGAGGEAGAADGSEAGGGAGGAEEAGEARGAGAGRAAGAAGGRAGRGADAAQEFIDRVARGPRLPLLPNTPEHGPGAPYLRRVVEWVEGALVGSFAVTARELAAMTDYVMAMLAECGFDDDGLADAMEPLIGEDDAPAFVRSLLFVAARCVTVGPSHLIPQQSAPPGGRGVVFLDTSDSDSEGSEDDSWSESEESSSGLSTSDLTAIDDTE... | suppression by virus of host intracellular interferon activity suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity symbiont-mediated disruption of host cell PML body host cell nucleus; host cell PML body DNA binding metal ion binding tran... |
cell division division septum assembly FtsZ-dependent cytokinesis | cell division site; cell septum; division septum; divisome complex; plasma membrane | peptidoglycan binding | Escherichia coli | 3D-structure Cell cycle Cell division Cell inner membrane Cell membrane Disulfide bond Membrane Reference proteome Repeat Septation Transmembrane Transmembrane helix | MAQRDYVRRS | MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVLVTFIGGLYFITHHKKEESETLQSQKVTGNGLPPKPEERWRYIKELESRQPGVRAPTEPSAGGEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTTAQSKPQQAAPVARAADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSKITTNNGWNRVVIGPVKGKENADSTLNRLKMAGHTNCIRLAAGG | cell division division septum assembly FtsZ-dependent cytokinesis cell division site; cell septum; division septum; divisome complex; plasma membrane peptidoglycan binding Escherichia coli 3D-structure Cell cycle Cell division Cell inner membrane Cell membrane Disulfide bond Membrane Reference proteome Repeat Septation... |
proteolysis | extracellular region | serine-type endopeptidase activity | Bacillus subtilis | Cell wall Direct protein sequencing Hydrolase Protease Reference proteome Secreted Serine protease Signal Zymogen | MKKGIIRFLL | MKKGIIRFLLVSFVLFFALSTGITGVQAAPASSKTSADLEKAEVFGDIDMTTSKKTTVIVELKEKSLAEAKEAGESQSKSKLKTARTKAKNKAIKAVKNGKVNREYEQVFSGFSMKLPANEIPKLLAVKDVKAVYPNVTYKTDNMKDKDVTISEDAVSPQMDDSAPYIGANDAWDLGYTGKGIKVAIIDTGVEYNHPDLKKNFGQYKGYDFVDNDYDPKETPTGDPRGEATDHGTHVAGTVAANGTIKGVAPDATLLAYRVLGPGGSGTTENVIAGVERAVQDGADVMNLSLGNSLNNPDWATSTALDWAMSEGVVAVTS... | proteolysis extracellular region serine-type endopeptidase activity Bacillus subtilis Cell wall Direct protein sequencing Hydrolase Protease Reference proteome Secreted Serine protease Signal Zymogen MKKGIIRFLL MKKGIIRFLLVSFVLFFALSTGITGVQAAPASSKTSADLEKAEVFGDIDMTTSKKTTVIVELKEKSLAEAKEAGESQSKSKLKTARTKAKNKAIKAVKNGKVNREYEQV... |
adipose tissue development liver development response to cadmium ion response to corticosterone response to estradiol response to ethanol response to growth hormone response to hormone response to insulin response to nutrient response to starvation response to toxic substance response to xenobiotic stimulus steroid met... | intracellular membrane-bounded organelle; matrix side of mitochondrial inner membrane; mitochondrial inner membrane; mitochondrial matrix | 3-hydroxybutyrate dehydrogenase activity phospholipid binding | Rattus norvegicus | Acetylation Allosteric enzyme Direct protein sequencing Glycoprotein Lipid metabolism Membrane Mitochondrion Mitochondrion inner membrane NAD Oxidoreductase Phosphoprotein Reference proteome Transit peptide | MLAARLSRPL | MLAARLSRPLSQLPGKALSVCDRENGTRHTLLFYPASFSPDTRRTYTSQADAASGKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLLKDKGDAGVRELDSLKSDRLRTIQLNVCNSEEVEKAVETVRSGLKDPEKGMWGLVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVRTTKSFLPLLRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMHPLGVKVSVVEPGNFIAATSLYSPERIQAIAKKMWDELPEVVRKDYGKKYFDEKIAKMETYCNSGSTDTSSVINAVTHALTAATPYTRYHPMDY... | adipose tissue development liver development response to cadmium ion response to corticosterone response to estradiol response to ethanol response to growth hormone response to hormone response to insulin response to nutrient response to starvation response to toxic substance response to xenobiotic stimulus steroid met... |
viral budding via host ESCRT complex | host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid | RNA binding structural constituent of virion zinc ion binding | Murine leukemia virus | Capsid protein Coiled coil Host cell membrane Host cytoplasm Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein RNA-binding Ubl conjugation Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral nucleoprotein Viral release from hos... | MGQTVTTPLS | MGQTVTTPLSLTLEHWGDVQRIASNQSVGVKKRRWVTFCSAEWPTFGVGWPQDGTFNLDIILQVKSKVFSPGPHGHPDQVPYIVTWEAIAYEPPPWVKPFVSPKLSLSPTAPILPSGPSTQPPPRSALYPAFTPSIKPRPSKPQVLSDDGGPLIDLLTEDPPPYGEQGPSSPDGDGDREEATSTSEIPAPSPMVSRLRGKRDPPAADSTTSRAFPLRLGGNGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLTTHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGNDGRPTQLPNEVNSAFPLERPDWDY... | viral budding via host ESCRT complex host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid RNA binding structural constituent of virion zinc ion binding Murine leukemia virus Capsid protein Coiled coil Host cell membrane Host cytoplasm Host endosome Host membrane Host-virus interaction Lipop... |
positive regulation of diacylglycerol kinase activity | axon; cytoplasm; cytosol; dendrite; extracellular region; microtubule; plasma membrane | microtubule binding | Bos taurus | Acetylation Alternative splicing Cell membrane Cell projection Cytoplasm Cytoskeleton Disulfide bond Glycoprotein Isopeptide bond Membrane Methylation Microtubule Phosphoprotein Reference proteome Repeat Secreted Ubl conjugation | MAEPRQEFDV | MAEPRQEFDVMEDHAQGDYTLQDQEGDMDPGLKESPLQTPADDGSEEPGSETSDAKSTPTAEDATAPLVDEGAPGEQAAAQAPAEIPEGTAAEEAGIGDTSNLEDQAAGHVTQARMVSKGKDGTGPDDKKTKGADGKPGTKIATPRGAAPPGQKGQANATRIPAKTTPTPKTSPATMQVQKKPPPAGAKSERGESGKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSAAKSRLQAAPGPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPV... | positive regulation of diacylglycerol kinase activity axon; cytoplasm; cytosol; dendrite; extracellular region; microtubule; plasma membrane microtubule binding Bos taurus Acetylation Alternative splicing Cell membrane Cell projection Cytoplasm Cytoskeleton Disulfide bond Glycoprotein Isopeptide bond Membrane Methylati... |
lipid catabolic process | extracellular space | all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity metal ion binding triglyceride lipase activity | Equus caballus | 3D-structure Calcium Direct protein sequencing Disulfide bond Hydrolase Lipid degradation Lipid metabolism Metal-binding Reference proteome Secreted Signal | WTLSLLLGAV | WTLSLLLGAVVGNEVCYERLGCFSDDSPWAGIVERPLKILPWSPEKVNTRFLLYTNENPDNFQEIVADPSTIQSSNFNTGRKTRFIIHGFIDKGEESWLSTMCQNMFKVESVNCICVDWKSGSRTAYSQASQNVRIVGAEVAYLVGVLQSSFDYSPSNVHIIGHSLGSHAAGEAGRRTNGAVGRITGLDPAEPCFQGTPELVRLDPSDAQFVDVIHTDIAPFIPNLGFGMSQTAGHLDFFPNGGKEMPGCQKNVLSQIVDIDGIWQGTRDFAACNHLRSYKYYTDSILNPDGFAGFSCASYSDFTANKCFPCSSEGCPQM... | lipid catabolic process extracellular space all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity metal ion binding triglyceride lipase activity Equus caballus 3D-structure Calcium Direct protein sequencing Disulfide bond Hydrolase Lipid degradation Lipid metabolism Metal-binding Reference proteome ... |
defense response to bacterium | extracellular region; nematocyst | potassium channel regulator activity toxin activity | Stichodactyla helianthus | 3D-structure Antibiotic Antimicrobial Direct protein sequencing Disulfide bond Ion channel impairing toxin Nematocyst Neurotoxin Pharmaceutical Potassium channel impairing toxin Secreted Toxin Voltage-gated potassium channel impairing toxin | RSCIDTIPKS | RSCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC | defense response to bacterium extracellular region; nematocyst potassium channel regulator activity toxin activity Stichodactyla helianthus 3D-structure Antibiotic Antimicrobial Direct protein sequencing Disulfide bond Ion channel impairing toxin Nematocyst Neurotoxin Pharmaceutical Potassium channel impairing toxin S... |
Group II intron splicing mitochondrion organization protein refolding response to heat | cytosol; cytosolic ribosome; mitochondrial matrix; mitochondrion; plant-type vacuole; polysomal ribosome | ATP binding ATP-dependent protein folding chaperone copper ion binding RNA binding structural constituent of ribosome | Arabidopsis thaliana | ATP-binding Chaperone Mitochondrion Nucleotide-binding Phosphoprotein Reference proteome Stress response Transit peptide | MYRFASNLAS | MYRFASNLASKARIAQNARQVSSRMSWSRNYAAKEIKFGVEARALMLKGVEDLADAVKVTMGPKGRNVVIEQSWGAPKVTKDGVTVAKSIEFKDKIKNVGASLVKQVANATNDVAGDGTTCATVLTRAIFAEGCKSVAAGMNAMDLRRGISMAVDAVVTNLKSKARMISTSEEIAQVGTISANGEREIGELIAKAMEKVGKEGVITIQDGKTLFNELEVVEGMKLDRGYTSPYFITNQKTQKCELDDPLILIHEKKISSINSIVKVLELALKRQRPLLIVSEDVESDALATLILNKLRAGIKVCAIKAPGFGENRKANLQ... | Group II intron splicing mitochondrion organization protein refolding response to heat cytosol; cytosolic ribosome; mitochondrial matrix; mitochondrion; plant-type vacuole; polysomal ribosome ATP binding ATP-dependent protein folding chaperone copper ion binding RNA binding structural constituent of ribosome Arabidopsi... |
cognition | clathrin-coated pit; early endosome; extracellular space; Golgi-associated vesicle; growth cone; perikaryon; recycling endosome | serine-type endopeptidase inhibitor activity | Macaca mulatta | Alternative splicing Amyloid Cell membrane Cell projection Coated pit Cytoplasmic vesicle Disulfide bond Endosome Membrane Protease inhibitor Reference proteome Serine protease inhibitor | EVCSEQAETG | EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVMSQSLRKTTREPLTRDPVKL | cognition clathrin-coated pit; early endosome; extracellular space; Golgi-associated vesicle; growth cone; perikaryon; recycling endosome serine-type endopeptidase inhibitor activity Macaca mulatta Alternative splicing Amyloid Cell membrane Cell projection Coated pit Cytoplasmic vesicle Disulfide bond Endosome Membrane... |
inositol biosynthetic process inositol metabolic process phosphate-containing compound metabolic process phosphatidylinositol biosynthetic process phosphatidylinositol phosphate biosynthetic process signal transduction | cytoplasm; cytosol | identical protein binding inositol monophosphate 1-phosphatase activity inositol monophosphate 3-phosphatase activity inositol monophosphate 4-phosphatase activity inositol monophosphate phosphatase activity lithium ion binding magnesium ion binding manganese ion binding protein homodimerization activity | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Hydrolase Intellectual disability Lithium Magnesium Metal-binding Phosphoprotein Reference proteome | MADPWQECMD | MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDED | inositol biosynthetic process inositol metabolic process phosphate-containing compound metabolic process phosphatidylinositol biosynthetic process phosphatidylinositol phosphate biosynthetic process signal transduction cytoplasm; cytosol identical protein binding inositol monophosphate 1-phosphatase activity inositol m... |
single fertilization | cytoplasmic vesicle; membrane | NAD(P)+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating transferase activity | Aplysia californica | 3D-structure Calcium Cytoplasmic vesicle Direct protein sequencing Disulfide bond Fertilization Hydrolase NAD NADP Phosphoprotein Signal Transferase | MSPVAIIACV | MSPVAIIACVCLAVTLTSISPSEAIVPTRELENVFLGRCKDYEITRYLDILPRVRSDCSALWKDFFKAFSFKNPCDLDLGSYKDFFTSAQQQLPKNKVMFWSGVYDEAHDYANTGRKYITLEDTLPGYMLNSLVWCGQRANPGFNEKVCPDFKTCPVQARESFWGMASSSYAHSAEGEVTYMVDGSNPKVPAYRPDSFFGKYELPNLTNKVTRVKVIVLHRLGEKIIEKCGAGSLLDLEKLVKAKHFAFDCVENPRAVLFLLCSDNPNARECRLAKRFYRIA | single fertilization cytoplasmic vesicle; membrane NAD(P)+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating transferase activity Aplysia californica 3D-structure Calcium Cytoplasmic vesicle Direct protein sequencing Disulfide bond Fertilization Hydrolase NAD NADP Phosphoprotein Signal Transferase M... |
fatty acid biosynthetic process lipid oxidation oxylipin biosynthetic process response to other organism response to wounding | cytoplasm | linoleate 13S-lipoxygenase activity linoleate 9S-lipoxygenase activity metal ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | Oryza sativa subsp. japonica | Cytoplasm Dioxygenase Fatty acid biosynthesis Fatty acid metabolism Iron Lipid biosynthesis Lipid metabolism Metal-binding Oxidoreductase Oxylipin biosynthesis Reference proteome | MLGGIIGGLT | MLGGIIGGLTGNKNARLKGSLVLMRKNALDINDFGATVIDGISEFLGRGVTCQLVSSSLVDPNNGNRGRVGTEASLEQWLTSLPSLTTGESKFGVTFEWEVEKMGIPGAIIVKNNHAAEFFLKTITLDNVPGHGAVVFVANSWIYPASKYRYNRVFFSNDTSLPSKMPAALKPYRDDELRNLRGDDQQGPYQEHDRVYRYDVYNDLGEPDSGNPRPVLGGSPDRPYPRRGRTGRKPTKTDPTAESRLSLLENIYVPRDERFGHLKMADFLGYSIKALVDGIVPAIRTYVDLTPGEFDSFKDILKLYEGGLKLPSIPALEE... | fatty acid biosynthetic process lipid oxidation oxylipin biosynthetic process response to other organism response to wounding cytoplasm linoleate 13S-lipoxygenase activity linoleate 9S-lipoxygenase activity metal ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorp... |
photosynthesis | plasma membrane-derived photosystem I; plasma membrane-derived thylakoid membrane | 4 iron, 4 sulfur cluster binding chlorophyll binding electron transfer activity magnesium ion binding | Synechocystis sp. | 3D-structure 4Fe-4S Chlorophyll Chromophore Direct protein sequencing Electron transport Iron Iron-sulfur Magnesium Membrane Metal-binding Oxidoreductase Photosynthesis Photosystem I Reference proteome Thylakoid Transmembrane Transmembrane helix Transport | MATKFPKFSQ | MATKFPKFSQDLAQDPTTRRIWYGIATAHDFETHDGMTEENLYQKIFASHFGHIAIIFLWTSGTLFHVAWQGNFEQWIKDPLNIRPIAHAIWDPHFGEGAVNAFTQAGASNPVNIAYSGVYHWFYTIGMTTNQELYSGAVFLLVLASLFLFAGWLHLQPKFRPSLAWFKNAESRLNHHLAGLFGVSSLAWAGHLVHVAIPEARGQHVGWDNFLSTPPHPAGLMPFFTGNWGVYAADPDTAGHIFGTSEGAGTAILTFLGGFHPQTESLWLTDIAHHHLAIAVIFIIAGHMYRTNWGIGHSIKEILNAHKGPLTGAGHTNL... | photosynthesis plasma membrane-derived photosystem I; plasma membrane-derived thylakoid membrane 4 iron, 4 sulfur cluster binding chlorophyll binding electron transfer activity magnesium ion binding Synechocystis sp. 3D-structure 4Fe-4S Chlorophyll Chromophore Direct protein sequencing Electron transport Iron Iron-sulf... |
activation of adenylate cyclase activity adenylate cyclase-activating G protein-coupled receptor signaling pathway cellular response to extracellular stimulus cGMP-mediated signaling G protein-coupled receptor signaling pathway mast cell degranulation positive regulation of cGMP-mediated signaling positive regulation o... | glutamatergic synapse; plasma membrane; presynapse; Schaffer collateral - CA1 synapse | G protein-coupled adenosine receptor activity G protein-coupled receptor activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MLLETQDALY | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNG... | activation of adenylate cyclase activity adenylate cyclase-activating G protein-coupled receptor signaling pathway cellular response to extracellular stimulus cGMP-mediated signaling G protein-coupled receptor signaling pathway mast cell degranulation positive regulation of cGMP-mediated signaling positive regulation o... |
angiogenesis cartilage condensation cell adhesion cell migration cell-matrix adhesion chondrocyte differentiation chondrocyte proliferation DNA biosynthetic process epidermis development fibroblast growth factor receptor signaling pathway integrin-mediated signaling pathway lung development negative regulation of gene ... | extracellular matrix; extracellular region; Golgi apparatus; intracellular membrane-bounded organelle; plasma membrane | heparin binding insulin-like growth factor binding integrin binding | Homo sapiens | Alternative splicing Cell adhesion Disulfide bond DNA synthesis Extracellular matrix Glycoprotein Heparin-binding Reference proteome Secreted Signal | MTAASMGPVR | MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCHFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFI... | angiogenesis cartilage condensation cell adhesion cell migration cell-matrix adhesion chondrocyte differentiation chondrocyte proliferation DNA biosynthetic process epidermis development fibroblast growth factor receptor signaling pathway integrin-mediated signaling pathway lung development negative regulation of gene ... |
acrosome matrix dispersal acrosome reaction activation of adenylate cyclase activity binding of sperm to zona pellucida penetration of zona pellucida protein catabolic process response to steroid hormone single fertilization | acrosomal matrix; acrosomal vesicle; Golgi-associated vesicle; protein-containing complex | amidase activity fucose binding mannose binding peptidase activity serine-type endopeptidase activity serine-type peptidase activity | Rattus norvegicus | Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MVEMLPTVVA | MVEMLPTVVALVLAVSVVAKDNTTCDGPCGLRFRQNPQAGIRIVGGQTSSPGAWPWMVSLQIFTSHNSRRYHACGGSLLNSHWVLTAAHCFDNKKKVYDWRLVFGAHEIEYGRNKPVKEPQQERYVQKIVIHEKYNAVTEGNDIALLKVTPPVTCGDFVGPGCLPHFKSGPPRIPHTCYVTGWGYIKDNAPRPSPVLMEARVDLIDLDLCNSTQWYNGRVTSTNVCAGYPEGKIDTCQGDSGGPLMCRDSVDSPFVIVGITSWGVGCARAKRPGVYTATWDYLDWIASKIGPTALHLIQPATPHPPTTQQPVISFHPPSI... | acrosome matrix dispersal acrosome reaction activation of adenylate cyclase activity binding of sperm to zona pellucida penetration of zona pellucida protein catabolic process response to steroid hormone single fertilization acrosomal matrix; acrosomal vesicle; Golgi-associated vesicle; protein-containing complex amida... |
DNA repair endocytosis meiotic chromosome segregation pexophagy phosphorylation positive regulation of clathrin-dependent endocytosis regulation of autophagosome assembly regulation of ER to Golgi vesicle-mediated transport regulation of protein localization regulation of protein localization by the Cvt pathway regulat... | cellular bud neck; cellular bud tip; chromosome, centromeric region; cytoplasm; cytosol; Golgi apparatus; monopolin complex; nucleolus; nucleoplasm; nucleus; plasma membrane; preribosome, small subunit precursor; spindle pole body | ATP binding identical protein binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Cytoplasm DNA damage DNA repair Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MDLRVGRKFR | MDLRVGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFLARLFKDLSIKLEYHNDHLFDWTMLRYTKAMVEKQRDLLIEKGDLNANSNAA... | DNA repair endocytosis meiotic chromosome segregation pexophagy phosphorylation positive regulation of clathrin-dependent endocytosis regulation of autophagosome assembly regulation of ER to Golgi vesicle-mediated transport regulation of protein localization regulation of protein localization by the Cvt pathway regulat... |
chromosome segregation cytoplasmic sequestering of protein germarium-derived oocyte fate determination learning or memory mitotic cell cycle, embryonic oocyte microtubule cytoskeleton polarization positive regulation of hippo signaling positive regulation of Ras protein signal transduction positive regulation of torso ... | cytoplasm; cytosol; early endosome; germline ring canal; nuclear membrane; nucleus; plasma membrane | molecular sequestering activity protein heterodimerization activity protein homodimerization activity transcription coactivator binding | Drosophila melanogaster | Alternative splicing Cytoplasm Developmental protein Differentiation Endosome Neurogenesis Reference proteome | MSTVDKEELV | MSTVDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRYLAEVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAEPQEGGDN | chromosome segregation cytoplasmic sequestering of protein germarium-derived oocyte fate determination learning or memory mitotic cell cycle, embryonic oocyte microtubule cytoskeleton polarization positive regulation of hippo signaling positive regulation of Ras protein signal transduction positive regulation of torso ... |
aggresome assembly ascospore formation DNA damage checkpoint signaling fungal-type cell wall chitin biosynthetic process mitotic spindle orientation checkpoint signaling negative regulation of apoptotic process negative regulation of protein ubiquitination negative regulation of transcription by RNA polymerase II pseud... | cytoplasm; cytoplasmic stress granule; nucleus; plasma membrane | DNA replication origin binding enzyme activator activity phosphoserine residue binding RNA polymerase II-specific DNA-binding transcription factor binding | Saccharomyces cerevisiae | 3D-structure Acetylation Isopeptide bond Phosphoprotein Reference proteome Ubl conjugation | MSTSREDSVY | MSTSREDSVYLAKLAEQAERYEEMVENMKTVASSGQELSVEERNLLSVAYKNVIGARRASWRIVSSIEQKEESKEKSEHQVELICSYRSKIETELTKISDDILSVLDSHLIPSATTGESKVFYYKMKGDYHRYLAEFSSGDAREKATNASLEAYKTASEIATTELPPTHPIRLGLALNFSVFYYEIQNSPDKACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMSESGQAEDQQQQQQHQQQQPPAAAEGEAPK | aggresome assembly ascospore formation DNA damage checkpoint signaling fungal-type cell wall chitin biosynthetic process mitotic spindle orientation checkpoint signaling negative regulation of apoptotic process negative regulation of protein ubiquitination negative regulation of transcription by RNA polymerase II pseud... |
axon guidance cell migration ephrin receptor signaling pathway fasciculation of motor neuron axon fasciculation of sensory neuron axon phosphorylation regulation of actin cytoskeleton organization regulation of epithelial to mesenchymal transition regulation of focal adhesion assembly regulation of GTPase activity regu... | dendrite; early endosome; plasma membrane | ATP binding ephrin receptor activity GPI-linked ephrin receptor activity transmembrane-ephrin receptor activity | Gallus gallus | ATP-binding Cell membrane Glycoprotein Kinase Membrane Nucleotide-binding Phosphoprotein Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase | MDRRRLPLLL | MDRRRLPLLLLCAALGSAGRLSARPGNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQESNVMDHSQNNWLRTNWIPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHLAKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEVREVGPVSKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNHSKEEEPPKMYCSTEGEWLVPIGKCLCNAGYEERGFACQACRPGFYKASAGNVKCAKCPPHSSTYEDASLNCRCEKNYFRSEKDPPSMA... | axon guidance cell migration ephrin receptor signaling pathway fasciculation of motor neuron axon fasciculation of sensory neuron axon phosphorylation regulation of actin cytoskeleton organization regulation of epithelial to mesenchymal transition regulation of focal adhesion assembly regulation of GTPase activity regu... |
axon guidance cell migration cellular response to follicle-stimulating hormone stimulus cellular response to retinoic acid endocardial cushion development ephrin receptor signaling pathway fasciculation of motor neuron axon fasciculation of sensory neuron axon negative regulation of endocytosis negative regulation of n... | actin cytoskeleton; cytosol; dendrite; early endosome; extracellular region; GABA-ergic synapse; nuclear membrane; nucleoplasm; plasma membrane; presynapse | ATP binding ephrin receptor activity GPI-linked ephrin receptor activity growth factor binding transmembrane-ephrin receptor activity | Mus musculus | Alternative splicing ATP-binding Cell membrane Glycoprotein Kinase Membrane Nucleotide-binding Phosphoprotein Receptor Reference proteome Repeat Secreted Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase | MDCHLSILVL | MDCHLSILVLLGCCVLSCSGELSPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCTCNAGYEERGFICQACRPGFYKASDGAAKCAKCPPHSSTQEDGSMNCRCENNYFRAEKDPPSMA... | axon guidance cell migration cellular response to follicle-stimulating hormone stimulus cellular response to retinoic acid endocardial cushion development ephrin receptor signaling pathway fasciculation of motor neuron axon fasciculation of sensory neuron axon negative regulation of endocytosis negative regulation of n... |
axon guidance cell adhesion cell migration cellular response to retinoic acid ephrin receptor signaling pathway fasciculation of motor neuron axon fasciculation of sensory neuron axon negative regulation of endocytosis peptidyl-tyrosine phosphorylation positive regulation of neuron projection development positive regul... | actin cytoskeleton; cytosol; dendrite; early endosome; extracellular region; nuclear membrane; nucleoplasm; plasma membrane | ATP binding ephrin receptor activity GPI-linked ephrin receptor activity transmembrane-ephrin receptor activity | Homo sapiens | 3D-structure Alternative splicing ATP-binding Cell adhesion Cell membrane Direct protein sequencing Glycoprotein Kinase Membrane Nucleotide-binding Phosphoprotein Receptor Reference proteome Repeat Secreted Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase | MDCQLSILLL | MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM... | axon guidance cell adhesion cell migration cellular response to retinoic acid ephrin receptor signaling pathway fasciculation of motor neuron axon fasciculation of sensory neuron axon negative regulation of endocytosis peptidyl-tyrosine phosphorylation positive regulation of neuron projection development positive regul... |
axon guidance cell adhesion cellular response to follicle-stimulating hormone stimulus ephrin receptor signaling pathway neuron projection development neuron remodeling phosphorylation positive regulation of MAPK cascade positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulatio... | early endosome membrane; neuron projection; plasma membrane; receptor complex | ATP binding ephrin receptor activity GPI-linked ephrin receptor activity growth factor binding transmembrane receptor protein tyrosine kinase activity | Rattus norvegicus | ATP-binding Cell adhesion Cell membrane Cell projection Developmental protein Endosome Kinase Membrane Neurogenesis Nucleotide-binding Phosphoprotein Receptor Reference proteome Transferase Tyrosine-protein kinase Ubl conjugation | RIHIEKIIGS | RIHIEKIIGSGESGEVCYGRLQVPGQRDVPVAIKALKAGYTERQRQDFLREAAIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDAFLRTHDGQFTILQLVGMLKGVGAGMRYLSDLGYIHRDLAARNILVDGRLVCKVSDFGLSRALEDDPEAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFSHVVSVLEALVHSPESLRATATVSRCPAPAFARSCFDLRAGGNGNGDLTVGDWLDSIRMGRYRDHFAA... | axon guidance cell adhesion cellular response to follicle-stimulating hormone stimulus ephrin receptor signaling pathway neuron projection development neuron remodeling phosphorylation positive regulation of MAPK cascade positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulatio... |
axon guidance cell adhesion cellular response to follicle-stimulating hormone stimulus ephrin receptor signaling pathway neuron projection development neuron remodeling phosphorylation positive regulation of MAPK cascade positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulatio... | dendrite; early endosome membrane; neuron projection; plasma membrane | ATP binding ephrin receptor activity GPI-linked ephrin receptor activity growth factor binding transmembrane-ephrin receptor activity | Homo sapiens | 3D-structure Alternative splicing ATP-binding Cell adhesion Cell membrane Cell projection Developmental protein Endosome Glycoprotein Kinase Membrane Neurogenesis Nucleotide-binding Phosphoprotein Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase Ubl conjuga... | MAPARGRLPP | MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDP... | axon guidance cell adhesion cellular response to follicle-stimulating hormone stimulus ephrin receptor signaling pathway neuron projection development neuron remodeling phosphorylation positive regulation of MAPK cascade positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulatio... |
entry receptor-mediated virion attachment to host cell viral entry into host cell | extracellular region; host cell endoplasmic reticulum; host cell Golgi apparatus; host cell nucleus; host cell surface; T=1 icosahedral viral capsid | RNA binding structural molecule activity | Hepatitis E virus genotype 1 | 3D-structure Alternative initiation Capsid protein Glycoprotein Host cytoplasm Host endoplasmic reticulum Host Golgi apparatus Host nucleus Host-virus interaction RNA-binding Secreted Signal T=1 icosahedral capsid protein Viral attachment to host cell Viral attachment to host entry receptor Virion Virus entry into host... | MRPRPILLLL | MRPRPILLLLLMFLPMLPAPPPGQPSGRRRGRRSGGSGGGFWGDRVDSQPFAIPYIHPTNPFAPDVTAAAGAGPRVRQPARPLGSAWRDQAQRPAVASRRRPTTAGAAPLTAVAPAHDTPPVPDVDSRGAILRRQYNLSTSPLTSSVATGTNLVLYAAPLSPLLPLQDGTNTHIMATEASNYAQYRVARATIRYRPLVPNAVGGYAISISFWPQTTTTPTSVDMNSITSTDVRILVQPGIASELVIPSERLHYRNQGWRSVETSGVAEEEATSGLVMLCIHGSLVNSYTNTPYTGALGLLDFALELEFRNLTPGNTNTRV... | entry receptor-mediated virion attachment to host cell viral entry into host cell extracellular region; host cell endoplasmic reticulum; host cell Golgi apparatus; host cell nucleus; host cell surface; T=1 icosahedral viral capsid RNA binding structural molecule activity Hepatitis E virus genotype 1 3D-structure Alter... |
cellular response to estradiol stimulus cellular response to glucocorticoid stimulus cellular response to oxygen levels cellular response to starvation cellular response to tumor necrosis factor DNA-templated transcription muscle organ development myoblast differentiation myoblast fate determination myoblast fusion myo... | euchromatin; myofibril; nucleoplasm; nucleus; transcription regulator complex | bHLH transcription factor binding chromatin binding chromatin DNA binding DNA-binding transcription activator activity DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity E-box binding nuclear receptor binding promoter-specific chromatin binding protein hom... | Ovis aries | Acetylation Activator Developmental protein Differentiation DNA-binding Methylation Myogenesis Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MELLSPPLRD | MELLSPPLRDVDLTGPDGSLCNFATADDFYDDPCFDSPDLRFFEDLDPRLVHVGALLKPEEHSHFPAAAHPAPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYAPGPLPPGRSGEHYSGDSDASSPRSNCSDGMMDYSGPPSGARRRNCYDRAYYSEAPNEPRPGKSAAVSSLDCLSSIVERISTESPAAPALLLADAPPESSPGPQEAAAGSEVECGTPAPSPDTAPQGLAGANPNPIYQVL | cellular response to estradiol stimulus cellular response to glucocorticoid stimulus cellular response to oxygen levels cellular response to starvation cellular response to tumor necrosis factor DNA-templated transcription muscle organ development myoblast differentiation myoblast fate determination myoblast fusion myo... |
mRNA export from nucleus regulation of translation translational initiation | cytoplasm; cytoplasmic stress granule; cytosol; eukaryotic translation initiation factor 4F complex; nuclear body; nuclear speck; nucleus; P-body; perinuclear region of cytoplasm | DNA-binding transcription factor binding enzyme binding eukaryotic initiation factor 4G binding mRNA cap binding RNA 7-methylguanosine cap binding translation initiation factor activity | Oryctolagus cuniculus | Acetylation Cytoplasm Initiation factor mRNA transport Nucleus Phosphoprotein Protein biosynthesis Reference proteome RNA-binding Translation regulation Transport | MATVEPETTP | MATVEPETTPTPNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV | mRNA export from nucleus regulation of translation translational initiation cytoplasm; cytoplasmic stress granule; cytosol; eukaryotic translation initiation factor 4F complex; nuclear body; nuclear speck; nucleus; P-body; perinuclear region of cytoplasm DNA-binding transcription factor binding enzyme binding eukaryoti... |
peroxisome organization protein autoubiquitination protein import into peroxisome matrix, receptor recycling protein monoubiquitination protein polyubiquitination protein ubiquitination | nucleus; peroxisome | ATP binding ubiquitin conjugating enzyme activity ubiquitin-protein transferase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Nucleotide-binding Peroxisome Peroxisome biogenesis Reference proteome Transferase Ubl conjugation pathway | MPNFWILENR | MPNFWILENRRSYTSDTCMSRIVKEYKVILKTLASDDPIANPYRGIIESLNPIDETDLSKWEAIISGPSDTPYENHQFRILIEVPSSYPMNPPKISFMQNNILHCNVKSATGEICLNILKPEEWTPVWDLLHCVHAVWRLLREPVCDSPLDVDIGNIIRCGDMSAYQGIVKYFLAERERINNH | peroxisome organization protein autoubiquitination protein import into peroxisome matrix, receptor recycling protein monoubiquitination protein polyubiquitination protein ubiquitination nucleus; peroxisome ATP binding ubiquitin conjugating enzyme activity ubiquitin-protein transferase activity Saccharomyces cerevisiae ... |
CRD-mediated mRNA stabilization mRNA processing negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay positive regulat... | catalytic step 2 spliceosome; cell leading edge; cytoplasm; cytoplasmic ribonucleoprotein granule; cytoplasmic stress granule; cytosol; dendrite; lamellipodium; mCRD-mediated mRNA stability complex; messenger ribonucleoprotein complex; nucleus; ribonucleoprotein complex; synapse | mRNA 3'-UTR binding mRNA binding poly(A) binding poly(U) RNA binding RNA binding | Mus musculus | Acetylation Cell projection Cytoplasm Methylation mRNA processing mRNA splicing Nonsense-mediated mRNA decay Nucleus Phosphoprotein Reference proteome Repeat RNA-binding Spliceosome | MNPSAPSYPM | MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTI... | CRD-mediated mRNA stabilization mRNA processing negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay positive regulat... |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway detection of chemical stimulus involved in sensory perception of bitter taste G protein-coupled receptor signaling pathway response to nicotine sensory perception of bitter taste sensory perception of sweet taste sensory perception of taste senso... | acrosomal vesicle; apical plasma membrane; axoneme; cytoplasm; heterotrimeric G-protein complex; photoreceptor inner segment; photoreceptor outer segment; plasma membrane; protein-containing complex | G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding | Rattus norvegicus | Cytoplasm GTP-binding Lipoprotein Magnesium Metal-binding Myristate Nucleotide-binding Reference proteome Sensory transduction Taste Transducer Vision | MGSGISSESK | MGSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSKQECMEFKAVVYSNTLQSILAIVKAMTTLGIDYVNPRSREDQQLLLSMANTLEDGDMTPQLAEIIKRLWGDPGIQACFERASEYQLNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDLFQEKVTKVHLSICFPEYTGPNTFEDAGNYIKNQFLDLNLKKEDKEIY... | adenylate cyclase-modulating G protein-coupled receptor signaling pathway detection of chemical stimulus involved in sensory perception of bitter taste G protein-coupled receptor signaling pathway response to nicotine sensory perception of bitter taste sensory perception of sweet taste sensory perception of taste senso... |
cell differentiation dephosphorylation dorsal/ventral axis specification, ovarian follicular epithelium epidermal growth factor receptor signaling pathway epithelial cell migration, open tracheal system fibroblast growth factor receptor signaling pathway imaginal disc development intracellular signal transduction mesod... | cytoplasm | non-membrane spanning protein tyrosine phosphatase activity phosphotyrosine residue binding transmembrane receptor protein tyrosine kinase adaptor activity | Drosophila melanogaster | Alternative splicing Cytoplasm Developmental protein Hydrolase Phosphoprotein Protein phosphatase Reference proteome Repeat SH2 domain | MSSRRWFHPT | MSSRRWFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLSVRRGNEVTHIKIQNNGDFFDLYGGEKFATLPELVQYYMENGELKEKNGQAIELKQPLICAEPTTERWFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTHVMIRWQDKKYDVGGGESFGTLSELIDHYKRNPMVETCGTVVHLRQPFNATRITAAGINARVEQLVKGGFWEEFESLQQDSRDTFSRNEGYKQENRLKNRYRNILPYDHTRVKLLDVEHSVAGAEYINANYIRLPTDGDLYNMSSSSESLNSSVPSCPACTAA... | cell differentiation dephosphorylation dorsal/ventral axis specification, ovarian follicular epithelium epidermal growth factor receptor signaling pathway epithelial cell migration, open tracheal system fibroblast growth factor receptor signaling pathway imaginal disc development intracellular signal transduction mesod... |
actin cytoskeleton organization angiogenesis cell-cell adhesion cellular response to growth factor stimulus defense response to bacterium epidermal growth factor receptor signaling pathway heart development insulin receptor signaling pathway insulin-like growth factor receptor signaling pathway intracellular signal tra... | cytosol; focal adhesion; mitochondrial matrix; plasma membrane; Shc-EGFR complex | ephrin receptor binding epidermal growth factor binding epidermal growth factor receptor binding insulin receptor binding insulin-like growth factor receptor binding neurotrophin TRKA receptor binding phospholipid binding phosphotyrosine residue binding receptor tyrosine kinase binding transmembrane receptor protein ty... | Homo sapiens | 3D-structure Acetylation Alternative promoter usage Alternative splicing Angiogenesis Cell junction Cytoplasm Growth regulation Host-virus interaction Mitochondrion Phosphoprotein Reference proteome SH2 domain | MDLLPPKPKY | MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCSFFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPP... | actin cytoskeleton organization angiogenesis cell-cell adhesion cellular response to growth factor stimulus defense response to bacterium epidermal growth factor receptor signaling pathway heart development insulin receptor signaling pathway insulin-like growth factor receptor signaling pathway intracellular signal tra... |
epidermal growth factor receptor signaling pathway male genitalia development muscle organ development regulation of cell migration regulation of cell projection organization regulation of MAPK cascade regulation of nematode larval development regulation of vulval development signal transduction | COP9 signalosome; cytoplasm; nucleoplasm; plasma membrane | epidermal growth factor receptor binding phosphotyrosine residue binding | Caenorhabditis elegans | 3D-structure Cell membrane Membrane Reference proteome Repeat SH2 domain SH3 domain | MEAVAEHDFQ | MEAVAEHDFQAGSPDELSFKRGNTLKVLNKDEDPHWYKAELDGNEGFIPSNYIRMTECNWYLGKITRNDAEVLLKKPTVRDGHFLVRQCESSPGEFSISVRFQDSVQHFKVLRDQNGKYYLWAVKFNSLNELVAYHRTASVSRTHTILLSDMNVETKFVQALFDFNPQESGELAFKRGDVITLINKDDPNWWEGQLNNRRGIFPSNYVCPYNSNKSNSNVAPGFNFGN | epidermal growth factor receptor signaling pathway male genitalia development muscle organ development regulation of cell migration regulation of cell projection organization regulation of MAPK cascade regulation of nematode larval development regulation of vulval development signal transduction COP9 signalosome; cytop... |
cell morphogenesis involved in conjugation with cellular fusion cellular bud site selection conjugation with cellular fusion maintenance of protein location regulation of Rho protein signal transduction | cell cortex; cellular bud neck; cellular bud tip; cytoplasm; cytoskeleton; incipient cellular bud site; mating projection tip; mitochondrion; PAR polarity complex; site of polarized growth | molecular adaptor activity phosphatidylinositol-3-phosphate binding protein-macromolecule adaptor activity | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Cytoskeleton Phosphoprotein Reference proteome Repeat SH3 domain | MLKNFKLSKR | MLKNFKLSKRDSNGSKGRITSADISTPSHDNGSVIKHIKTVPVRYLSSSSTPVKSQRDSSPKNRHNSKDITSPEKVIKAKYSYQAQTSKELSFMEGEFFYVSGDEKDWYKASNPSTGKEGVVPKTYFEVFDRTKPSSVNGSNSSSRKVTNDSLNMGSLYAIVLYDFKAEKADELTTYVGENLFICAHHNCEWFIAKPIGRLGGPGLVPVGFVSIIDIATGYATGNDVIEDIKSVNLPTVQEWKSNIARYKASNISLGSVEQQQQQSITKPQNKSAKLVDGELLVKASVESFGLEDEKYWFLVCCELSNGKTRQLKRYYQD... | cell morphogenesis involved in conjugation with cellular fusion cellular bud site selection conjugation with cellular fusion maintenance of protein location regulation of Rho protein signal transduction cell cortex; cellular bud neck; cellular bud tip; cytoplasm; cytoskeleton; incipient cellular bud site; mating projec... |
positive regulation of blood pressure positive regulation of flagellated sperm motility positive regulation of heart rate positive regulation of uterine smooth muscle contraction regulation of dopamine metabolic process regulation of feeding behavior response to cocaine response to estradiol tachykinin receptor signali... | dendrite membrane; neuronal cell body membrane; plasma membrane; sperm midpiece | tachykinin receptor activity | Homo sapiens | Cell membrane Disease variant Disulfide bond G-protein coupled receptor Glycoprotein Hypogonadotropic hypogonadism Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MATLPAAETW | MATLPAAETWIDGGGGVGADAVNLTASLAAGAATGAVETGWLQLLDQAGNLSSSPSALGLPVASPAPSQPWANLTNQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKTKVMPGRTLCFVQWPEGPKQHFTYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVMTFAICWLPYHIYFI... | positive regulation of blood pressure positive regulation of flagellated sperm motility positive regulation of heart rate positive regulation of uterine smooth muscle contraction regulation of dopamine metabolic process regulation of feeding behavior response to cocaine response to estradiol tachykinin receptor signali... |
base-excision repair depurination DNA dealkylation involved in DNA repair | cytosol; mitochondrial nucleoid; nucleoplasm | alkylbase DNA N-glycosylase activity damaged DNA binding DNA N-glycosylase activity DNA-3-methyladenine glycosylase activity DNA-3-methylguanine glycosylase activity DNA-7-methyladenine glycosylase activity DNA-7-methylguanine glycosylase activity | Homo sapiens | 3D-structure Alternative splicing Cytoplasm DNA damage DNA repair Hydrolase Mitochondrion Mitochondrion nucleoid Nucleus Phosphoprotein Reference proteome Transit peptide | MVTPALQMKK | MVTPALQMKKPKQFCRRMGQKKQRPARAGQPHSSSDAAQAPAEQPHSSSDAAQAPCPRERCLGPPTTPGPYRSIYFSSPKGHLTRLGLEFFDQPAVPLARAFLGQVLVRRLPNGTELRGRIVETEAYLGPEDEAAHSRGGRQTPRNRGMFMKPGTLYVYIIYGMYFCMNISSQGDGACVLLRALEPLEGLETMRQLRSTLRKGTASRVLKDRELCSGPSKLCQALAINKSFDQRDLAQDEAVWLERGPLEPSEPAVVAAARVGVGHAGEWARKPLRFYVRGSPWVSVVDRVAEQDTQA | base-excision repair depurination DNA dealkylation involved in DNA repair cytosol; mitochondrial nucleoid; nucleoplasm alkylbase DNA N-glycosylase activity damaged DNA binding DNA N-glycosylase activity DNA-3-methyladenine glycosylase activity DNA-3-methylguanine glycosylase activity DNA-7-methyladenine glycosylase act... |
embryonic forelimb morphogenesis epidermis development fatty acid transport positive regulation of collateral sprouting regulation of DNA-templated transcription retinoic acid metabolic process signal transduction | cytoplasm; cytosol; endoplasmic reticulum; extracellular exosome; nucleoplasm; nucleus | cyclin binding fatty acid binding retinal binding retinoic acid binding retinoid binding retinol binding | Homo sapiens | 3D-structure Cytoplasm Endoplasmic reticulum Isopeptide bond Nucleus Reference proteome Retinol-binding Transport Ubl conjugation Vitamin A | MPNFSGNWKI | MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVRTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGELILTMTADDVVCTRVYVRE | embryonic forelimb morphogenesis epidermis development fatty acid transport positive regulation of collateral sprouting regulation of DNA-templated transcription retinoic acid metabolic process signal transduction cytoplasm; cytosol; endoplasmic reticulum; extracellular exosome; nucleoplasm; nucleus cyclin binding fatt... |
cell population proliferation cellular response to retinoic acid negative regulation of apoptotic process peptidyl-tyrosine autophosphorylation positive regulation of cardiac muscle cell apoptotic process positive regulation of neuron projection development positive regulation of phosphatidylinositol 3-kinase/protein k... | membrane; plasma membrane; receptor complex | ATP binding protein kinase activity protein tyrosine kinase activity receptor signaling protein tyrosine kinase activator activity transmembrane receptor protein tyrosine kinase activity | Homo sapiens | 3D-structure Alternative splicing ATP-binding Cell membrane Disulfide bond Glycoprotein Kinase Membrane Nucleotide-binding Phosphoprotein Receptor Reference proteome Signal Systemic lupus erythematosus Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase | MGCWGQLLVW | MGCWGQLLVWFGAAGAILCSSPGSQETFLRSSPLPLASPSPRDPKVSAPPSILEPASPLNSPGTEGSWLFSTCGASGRHGPTQTQCDGAYAGTSVVVTVGAAGQLRGVQLWRVPGPGQYLISAYGAAGGKGAKNHLSRAHGVFVSAIFSLGLGESLYILVGQQGEDACPGGSPESQLVCLGESRAVEEHAAMDGSEGVPGSRRWAGGGGGGGGATYVFRVRAGELEPLLVAAGGGGRAYLRPRDRGRTQASPEKLENRSEAPGSGGRGGAAGGGGGWTSRAPSPQAGRSLQEGAEGGQGCSEAWATLGWAAAGGFGGGGG... | cell population proliferation cellular response to retinoic acid negative regulation of apoptotic process peptidyl-tyrosine autophosphorylation positive regulation of cardiac muscle cell apoptotic process positive regulation of neuron projection development positive regulation of phosphatidylinositol 3-kinase/protein k... |
cell differentiation plant ovule development positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Arabidopsis thaliana | Activator Alternative splicing Coiled coil Developmental protein Differentiation DNA-binding Flowering Nucleus Reference proteome Transcription Transcription regulation | MGRGRVELKR | MGRGRVELKRIENKINRQVTFAKRRNGLLKKAYELSVLCDAEVALIIFSNRGKLYEFCSSSNMLKTLDRYQKCSYGSIEVNNKPAKELENSYREYLKLKGRYENLQRQQRNLLGEDLGPLNSKELEQLERQLDGSLKQVRSIKTQYMLDQLSDLQNKEQMLLETNRALAMKLDDMIGVRSHHMGGGGGWEGGEQNVTYAHHQAQSQGLYQPLECNPTLQMGYDNPVCSEQITATTQAQAQQGNGYIPGWML | cell differentiation plant ovule development positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DN... |
carpel development cell differentiation maintenance of floral meristem identity petal development positive regulation of transcription by RNA polymerase II sepal development stamen development | nucleus | DNA-binding transcription factor activity protein dimerization activity RNA polymerase II transcription regulatory region sequence-specific DNA binding | Arabidopsis thaliana | Alternative splicing Developmental protein Differentiation DNA-binding Flowering Nucleus Reference proteome Transcription Transcription regulation | MGRGKVELKR | MGRGKVELKRIENKINRQVTFAKRRNGLLKKAYELSVLCDAEIALLIFSNRGKLYEFCSSPSGMARTVDKYRKHSYATMDPNQSAKDLQDKYQDYLKLKSRVEILQHSQRHLLGEELSEMDVNELEHLERQVDASLRQIRSTKARSMLDQLSDLKTKEEMLLETNRDLRRKLEDSDAALTQSFWGSSAAEQQQQHQQQQQGMSSYQSNPPIQEAGFFKPLQGNVALQMSSHYNHNPANATNSATTSQNVNGFFPGWMV | carpel development cell differentiation maintenance of floral meristem identity petal development positive regulation of transcription by RNA polymerase II sepal development stamen development nucleus DNA-binding transcription factor activity protein dimerization activity RNA polymerase II transcription regulatory regi... |
carpel development plant ovule development positive regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity protein dimerization activity RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription cis-regulatory region binding | Arabidopsis thaliana | Alternative splicing Developmental protein DNA-binding Flowering Growth regulation Nucleus Reference proteome Transcription Transcription regulation | MEGGASNEVA | MEGGASNEVAESSKKIGRGKIEIKRIENTTNRQVTFCKRRNGLLKKAYELSVLCDAEVALVIFSTRGRLYEYANNSVRGTIERYKKACSDAVNPPTITEANTQYYQQEASKLRRQIRDIQNLNRHILGESLGSLNFKELKNLESRLEKGISRVRSKKHEMLVAEIEYMQKREIELQNDNMYLRSKITERTGLQQQESSVIHQGTVYESGVTSSHQSGQYNRNYIAVNLLEPNQNSSNQDQPPLQLV | carpel development plant ovule development positive regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity protein dimerization activity RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription cis-regulatory region binding Arabidopsis tha... |
intracellular sequestering of iron ion iron ion transport | chloroplast; cytoplasm | ferric iron binding ferrous iron binding ferroxidase activity | Zea mays | Chloroplast Direct protein sequencing Iron Iron storage Metal-binding Oxidoreductase Plastid Reference proteome Transit peptide | MMLRVSSSPA | MMLRVSSSPAAAVANHLSGGAAATTAPARVTAQRSGVSLSAAAAAGKGKEVLSGVVFQPFEEIKGELALVPQSPDRSLARHKFVDDCEAAINEQINVEYNASYAYHSLFAYFDRDNVALKGFAKFFKESSDEEREHAEKLMEYQNKRGGRVRLQSIVAPLTEFDHPEKGDALYAMELTLALEKLVNEKLHSLHGVATRCNDPQLIDFIESEFLEEQGEAINKVSKYVAQLRRVGNKGHGVWHFDQMLLQEAA | intracellular sequestering of iron ion iron ion transport chloroplast; cytoplasm ferric iron binding ferrous iron binding ferroxidase activity Zea mays Chloroplast Direct protein sequencing Iron Iron storage Metal-binding Oxidoreductase Plastid Reference proteome Transit peptide MMLRVSSSPA MMLRVSSSPAAAVANHLSGGAAATTAPAR... |
glyceraldehyde-3-phosphate biosynthetic process pentose-phosphate shunt pentose-phosphate shunt, non-oxidative branch regulation of growth xylulose 5-phosphate biosynthetic process | cytosol; endoplasmic reticulum membrane; extracellular exosome; nuclear body; nucleoplasm; peroxisome; vesicle | calcium ion binding magnesium ion binding protein homodimerization activity thiamine pyrophosphate binding transketolase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Calcium Direct protein sequencing Disease variant Dwarfism Isopeptide bond Magnesium Metal-binding Phosphoprotein Reference proteome Thiamine pyrophosphate Transferase Ubl conjugation | MESYHKPDQQ | MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKA... | glyceraldehyde-3-phosphate biosynthetic process pentose-phosphate shunt pentose-phosphate shunt, non-oxidative branch regulation of growth xylulose 5-phosphate biosynthetic process cytosol; endoplasmic reticulum membrane; extracellular exosome; nuclear body; nucleoplasm; peroxisome; vesicle calcium ion binding magnesiu... |
adenine metabolic process ADP biosynthetic process AMP metabolic process ATP metabolic process dATP metabolic process liver development oxidative phosphorylation phosphorylation response to thyroid hormone | cytoplasm; mitochondrial intermembrane space; mitochondrion; sperm flagellum; sperm mitochondrial sheath | adenylate kinase activity ATP binding | Rattus norvegicus | Acetylation Alternative splicing ATP-binding Disulfide bond Kinase Mitochondrion Nucleotide-binding Phosphoprotein Reference proteome Transferase | MAPNALAPEP | MAPNALAPEPEHPEGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVKQAEMLDDLMDKRKEKLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEAMKDDITGEPLIRRSDDNEKALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDVVFASILAAFSKATCKDLVMFV | adenine metabolic process ADP biosynthetic process AMP metabolic process ATP metabolic process dATP metabolic process liver development oxidative phosphorylation phosphorylation response to thyroid hormone cytoplasm; mitochondrial intermembrane space; mitochondrion; sperm flagellum; sperm mitochondrial sheath adenylate... |
ADP biosynthetic process AMP metabolic process AMP phosphorylation cerebellum development dATP metabolic process GTP metabolic process ITP metabolic process liver development muscle organ development nucleoside triphosphate biosynthetic process olfactory bulb development phosphorylation response to starvation UTP metab... | cytoplasm; mitochondrial matrix; mitochondrion | adenylate kinase activity ATP binding GTP binding identical protein binding nucleoside triphosphate adenylate kinase activity | Rattus norvegicus | Acetylation GTP-binding Kinase Mitochondrion Nucleotide-binding Phosphoprotein Reference proteome Transferase | MGASGRLLRA | MGASGRLLRAVIMGAPGSGKGTGSSRITKHFELKHLSSGDLLRQNMLQGTEIAVLAKSFIDQGKLIPDDDMTRLALHELKNLTQCSWLLDGFPRTLPQAEALDRVYQIDTVINLNVPFEVIKLRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQTEPVLQYYQKKGVLETFSGTETNKIRPHVYSFLQMKVPETIQKASVTP | ADP biosynthetic process AMP metabolic process AMP phosphorylation cerebellum development dATP metabolic process GTP metabolic process ITP metabolic process liver development muscle organ development nucleoside triphosphate biosynthetic process olfactory bulb development phosphorylation response to starvation UTP metab... |
olfactory behavior protein folding sleep ubiquitin-dependent ERAD pathway | endomembrane system; endoplasmic reticulum lumen; endoplasmic reticulum membrane; extracellular space; fusome | calcium ion binding carbohydrate binding unfolded protein binding | Drosophila melanogaster | Calcium Chaperone Direct protein sequencing Disulfide bond Endoplasmic reticulum Lectin Metal-binding Reference proteome Repeat Signal Zinc | MMWCKTVIVL | MMWCKTVIVLLATVGFISAEVYLKENFDNENWEDTWIYSKHPGKEFGKFVLTPGTFYNDAEADKGIQTSQDARFYAASRKFDGFSNEDKPLVVQFSVKHEQNIDCGGGYVKLFDCSLDQTDMHGESPYEIMFGPDICGPGTKKVHVIFSYKGKNHLISKDIRCKDDVYTHFYTLIVRPDNTYEVLIDNEKVESGNLEDDWDFLAPKKIKDPTATKPEDWDDRATIPDPDDKKPEDWDKPEHIPDPDATKPEDWDDEMDGEWEPPMIDNPEFKGEWQPKQLDNPNYKGAWEHPEIANPEYVPDDKLYLRKEICTLGFDLWQ... | olfactory behavior protein folding sleep ubiquitin-dependent ERAD pathway endomembrane system; endoplasmic reticulum lumen; endoplasmic reticulum membrane; extracellular space; fusome calcium ion binding carbohydrate binding unfolded protein binding Drosophila melanogaster Calcium Chaperone Direct protein sequencing Di... |
cell-cell signaling gap junction-mediated intercellular transport response to hydrogen peroxide response to pH visual perception | connexin complex; gap junction; plasma membrane | gap junction channel activity gap junction hemi-channel activity identical protein binding | Rattus norvegicus | Cell junction Cell membrane Disulfide bond Gap junction Membrane Reference proteome Transmembrane Transmembrane helix | MGDWSFLGRL | MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEEVWGDEQSDFTCNTQQPGCENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEELLRRDNPQHGRGREPMRTGSPRDPPLRDDRGKVRIAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFQLQPLYRCDRWPCPNTVDCFISRPTEKTIFVIFMLAVACASLVLNMLEIYHLGWKKLKQGVTNHFNPDASEVRHKPLDPLSEAANSGPPSVSIGLPPYYTHPACPTVQGKATGFPGAPLLPADFTVVTLNDAQGRGHPVKH... | cell-cell signaling gap junction-mediated intercellular transport response to hydrogen peroxide response to pH visual perception connexin complex; gap junction; plasma membrane gap junction channel activity gap junction hemi-channel activity identical protein binding Rattus norvegicus Cell junction Cell membrane Disulf... |
adult walking behavior cell morphogenesis involved in neuron differentiation dermatan sulfate catabolic process ganglioside catabolic process glycosaminoglycan biosynthetic process glycosaminoglycan metabolic process hyaluronan catabolic process lipid storage locomotory behavior lysosome organization maintenance of loc... | azurophil granule; beta-N-acetylhexosaminidase complex; cytosol; intracellular membrane-bounded organelle; lysosomal lumen; lysosome; membrane | acetylglucosaminyltransferase activity beta-N-acetylhexosaminidase activity N-acetyl-beta-D-galactosaminidase activity protein heterodimerization activity | Mus musculus | Disulfide bond Glycoprotein Glycosidase Hydrolase Lipid metabolism Lysosome Reference proteome Signal Zymogen | MAGCRLWVSL | MAGCRLWVSLLLAAALACLATALWPWPQYIQTYHRRYTLYPNNFQFRYHVSSAAQAGCVVLDEAFRRYRNLLFGSGSWPRPSFSNKQQTLGKNILVVSVVTAECNEFPNLESVENYTLTINDDQCLLASETVWGALRGLETFSQLVWKSAEGTFFINKTKIKDFPRFPHRGVLLDTSRHYLPLSSILDTLDVMAYNKFNVFHWHLVDDSSFPYESFTFPELTRKGSFNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGAPGLLTPCYSGSHLSGTFGPVNPSLNSTYDFMSTLFLEISSVFPDFYLHLG... | adult walking behavior cell morphogenesis involved in neuron differentiation dermatan sulfate catabolic process ganglioside catabolic process glycosaminoglycan biosynthetic process glycosaminoglycan metabolic process hyaluronan catabolic process lipid storage locomotory behavior lysosome organization maintenance of loc... |
proton motive force-driven mitochondrial ATP synthesis | mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1); proton-transporting ATP synthase complex, catalytic core F(1) | protein-containing complex binding proton-transporting ATP synthase activity, rotational mechanism | Rattus norvegicus | Acetylation ATP synthesis CF(1) Direct protein sequencing Hydrogen ion transport Ion transport Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Transport | MVAYWRQAGL | MVAYWRQAGLSYIRFSQICAKAVRDALKTEFKANAEKTSGTSIKTVKIKKE | proton motive force-driven mitochondrial ATP synthesis mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1); proton-transporting ATP synthase complex, catalytic core F(1) protein-containing complex binding pro... |
hydrogen peroxide catabolic process response to oxidative stress | cytoplasm | catalase activity heme binding metal ion binding | Micrococcus luteus | 3D-structure Cytoplasm Direct protein sequencing Heme Hydrogen peroxide Iron Metal-binding NADP Oxidoreductase Peroxidase | MEHQKTTPHA | MEHQKTTPHATGSTRQNGAPAVSDRQSLTVGSEGPIVLHDTHLLETHQHFNRMNIPERRPHAKGSGAFGEFEVTEDVSKYTKALVFQPGTKTETLLRFSTVAGELGSPDTWRDVRGFALRFYTEEGNYDLVGNNTPIFFLRDPMKFTHFIRSQKRLPDSGLRDATMQWDFWTNNPESAHQVTYLMGPRGLPRTWREMNGYGSHTYLWVNAQGEKHWVKYHFISQQGVHNLSNDEATKIAGENADFHRQDLFESIAKGDHPKWDLYIQAIPYEEGKTYRFNPFDLTKTISQKDYPRIKVGTLTLNRNPENHFAQIESAAFS... | hydrogen peroxide catabolic process response to oxidative stress cytoplasm catalase activity heme binding metal ion binding Micrococcus luteus 3D-structure Cytoplasm Direct protein sequencing Heme Hydrogen peroxide Iron Metal-binding NADP Oxidoreductase Peroxidase MEHQKTTPHA MEHQKTTPHATGSTRQNGAPAVSDRQSLTVGSEGPIVLHDTHLL... |
positive regulation of catalytic activity | cytosol | enzyme activator activity oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor protein-disulfide reductase activity | Arabidopsis thaliana | 3D-structure Acetylation Cytoplasm Disulfide bond Electron transport Redox-active center Reference proteome Transport | MASEEGQVIA | MASEEGQVIACHTVETWNEQLQKANESKTLVVVDFTASWCGPCRFIAPFFADLAKKLPNVLFLKVDTDELKSVASDWAIQAMPTFMFLKEGKILDKVVGAKKDELQSTIAKHLA | positive regulation of catalytic activity cytosol enzyme activator activity oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor protein-disulfide reductase activity Arabidopsis thaliana 3D-structure Acetylation Cytoplasm Disulfide bond Electron transport Redox-active center Reference prot... |
cytoplasmic translation maturation of LSU-rRNA | cytosol; cytosolic large ribosomal subunit | RNA binding structural constituent of ribosome | Saccharomyces cerevisiae | Cytoplasm Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein | MAPGKKVAPA | MAPGKKVAPAPFGAKSTKSNKAKNPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRLQRQKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETAAEKKERLTKEAAAIAEGKSKQDASPKPYAVKYGLNHVVSLIENKKAKLVLIANDVDPIELVVFLPALCKKMGVPYAIIKGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTIDANFADKYDEVKKHWGGGILGNKAQAKMDKRAKTSDSA | cytoplasmic translation maturation of LSU-rRNA cytosol; cytosolic large ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae Cytoplasm Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein MAPGKKVAPA MAPGKKVAPAPFGAKSTKSNKAKNPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEY... |
acute-phase response cellular response to interleukin-6 glucose homeostasis hepatocyte proliferation interleukin-6-mediated signaling pathway liver regeneration positive regulation of B cell activation positive regulation of receptor signaling pathway via STAT positive regulation of T cell activation regulation of gluc... | extracellular space | cytokine activity growth factor activity interleukin-6 receptor binding | Ovis aries | Acute phase Cytokine Disulfide bond Glycoprotein Growth factor Phosphoprotein Reference proteome Secreted Signal | MNSLFTSAFS | MNSLFTSAFSPLAVSLGLLLVMTSAFPTPGPLGEDFKNDTTPSRLLLTTPEKTEALIKHIVDKISAIRKEICEKNDECENSKETLAENKLKLPKMEEKDGCFQSGFNQAICLIKTTAGLLEYQIYLDFLQNEFEGNQETVMELQSSIRTLIQILKEKIAGLITTPATHTDMLEKMQSSNEWVKNAKVIIILRSLENFLQFSLRAIRMK | acute-phase response cellular response to interleukin-6 glucose homeostasis hepatocyte proliferation interleukin-6-mediated signaling pathway liver regeneration positive regulation of B cell activation positive regulation of receptor signaling pathway via STAT positive regulation of T cell activation regulation of gluc... |
chondrocyte development involved in endochondral bone morphogenesis collagen biosynthetic process collagen fibril organization protein maturation response to organic cyclic compound response to vitamin D | cytoplasm; endoplasmic reticulum; endoplasmic reticulum lumen; endoplasmic reticulum-Golgi intermediate compartment; extracellular space; membrane raft | collagen binding serine-type endopeptidase inhibitor activity unfolded protein binding | Rattus norvegicus | Acetylation Chaperone Direct protein sequencing Endoplasmic reticulum Glycoprotein Phosphoprotein Reference proteome Signal Stress response | MRSLLLGTLC | MRSLLLGTLCLLAVALAAEVKKPVEAAAPGTAEKLSSKATTLAERSTGLAFSLYQAMAKDQAVENILLSPLVVASSLGLVSLGGKATTASQAKAVLSAEKLRDEEVHTGLGELVRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWASQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVTMMHRTGLYNYYDDEKEKLQLVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKTWMGKMQKKAVAISLPKGVVEVTHDLQKHL... | chondrocyte development involved in endochondral bone morphogenesis collagen biosynthetic process collagen fibril organization protein maturation response to organic cyclic compound response to vitamin D cytoplasm; endoplasmic reticulum; endoplasmic reticulum lumen; endoplasmic reticulum-Golgi intermediate compartment;... |
DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation premeiotic DNA replication | chromatin; DNA replication preinitiation complex; MCM complex; MCM core complex; nuclear pre-replicative complex; nuclear replication fork; nucleus; rDNA protrusion | ATP binding ATP hydrolysis activity chromatin binding DNA binding DNA helicase activity | Schizosaccharomyces pombe | ATP-binding DNA replication DNA-binding Helicase Hydrolase Nucleotide-binding Nucleus Phosphoprotein Reference proteome | MSSSQQSGRA | MSSSQQSGRANELRTPGRANSSSREAVDSSPLFFPASSPGSTRLTTPRTTARTPLASSPLLFESSSPGPNIPQSSRSHLLSQRNDLFLDSSSQRTPRSTRRGDIHSSVQMSTPSRRREVDPQRPGVSTPSSLLFSGSDALTFSQAHPSSEVADDTVRVIWGTNVSIQESIASFRGFLRGFKKKYRPEYRNELMPPPDAEQLVYIEALRNMRIMGLEILNLDVQDLKHYPPTKKLYHQLYSYPQEIIPIMDQTIKDVMLDLLGTNPPEDVLNDIELKIYKIRPFNLEKCINMRDLNPGDIDKLISIKGLVLRCTPVIPDMK... | DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation premeiotic DNA replication chromatin; DNA replication preinitiation complex; MCM complex; MCM core complex; nuclear pre-replicative comp... |
dephosphorylation maintenance of protein location in nucleus regulation of sporulation | cytoplasm; nucleus | protein tyrosine phosphatase activity | Saccharomyces cerevisiae | Cytoplasm Hydrolase Nucleus Phosphoprotein Protein phosphatase Reference proteome | MDRIAQQYRN | MDRIAQQYRNGKRDNNGNRMASSAISEKGHIQVNQTRTPGQMPVYRGETINLSNLPQNQIKPCKDLDDVNIRRNNSNRHSKILLLDLCAGPNTNSFLGNTNAKDITVLSLPLPSTLVKRSNYPFENLLKNYLGSDEKYIEFTKIIKDYDIFIFSDSFSRISSCLKTTFCLIEKFKKFICHFFPSPYLKFFLLEGSLNDSKAPSLGKNKKNCILPKLDLNLNVNLTSRSTLNLRINIPPPNDSNKIFLQSLKKDLIHYSPNSLQKFFQFNMPADLAPNDTILPNWLKFCSVKENEKVILKKLFNNFETLENFEMQRLEKCL... | dephosphorylation maintenance of protein location in nucleus regulation of sporulation cytoplasm; nucleus protein tyrosine phosphatase activity Saccharomyces cerevisiae Cytoplasm Hydrolase Nucleus Phosphoprotein Protein phosphatase Reference proteome MDRIAQQYRN MDRIAQQYRNGKRDNNGNRMASSAISEKGHIQVNQTRTPGQMPVYRGETINLSNLPQ... |
AIM2 inflammasome complex assembly apoptotic process cellular response to lipopolysaccharide cellular response to mechanical stimulus cellular response to organic substance cellular response to type II interferon cytokine precursor processing defense response to bacterium defense response to virus icosanoid biosyntheti... | AIM2 inflammasome complex; canonical inflammasome complex; cytoplasm; cytosol; IPAF inflammasome complex; microtubule; NLRP1 inflammasome complex; NLRP3 inflammasome complex; nucleolus; plasma membrane; protease inhibitor complex; protein-containing complex | CARD domain binding caspase binding cysteine-type endopeptidase activator activity involved in apoptotic process cysteine-type endopeptidase activity endopeptidase activity identical protein binding kinase binding | Homo sapiens | 3D-structure Alternative splicing Apoptosis Cell membrane Cytoplasm Direct protein sequencing Hydrolase Isopeptide bond Membrane Phosphoprotein Protease Reference proteome Thiol protease Ubl conjugation Zymogen | MADKVLKEKR | MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKK... | AIM2 inflammasome complex assembly apoptotic process cellular response to lipopolysaccharide cellular response to mechanical stimulus cellular response to organic substance cellular response to type II interferon cytokine precursor processing defense response to bacterium defense response to virus icosanoid biosyntheti... |
mRNA 3'-end processing mRNA polyadenylation sno(s)RNA 3'-end processing termination of RNA polymerase II transcription, poly(A)-coupled | mRNA cleavage and polyadenylation specificity factor complex; nucleus | ATP binding magnesium ion binding poly(A) RNA polymerase activity RNA binding | Saccharomyces cerevisiae | 3D-structure ATP-binding Direct protein sequencing Magnesium Manganese Metal-binding mRNA processing Nucleotide-binding Nucleus Phosphoprotein Reference proteome RNA-binding Transferase | MSSQKVFGIT | MSSQKVFGITGPVSTVGATAAENKLNDSLIQELKKEGSFETEQETANRVQVLKILQELAQRFVYEVSKKKNMSDGMARDAGGKIFTYGSYRLGVHGPGSDIDTLVVVPKHVTREDFFTVFDSLLRERKELDEIAPVPDAFVPIIKIKFSGISIDLICARLDQPQVPLSLTLSDKNLLRNLDEKDLRALNGTRVTDEILELVPKPNVFRIALRAIKLWAQRRAVYANIFGFPGGVAWAMLVARICQLYPNACSAVILNRFFIILSEWNWPQPVILKPIEDGPLQVRVWNPKIYAQDRSHRMPVITPAYPSMCATHNITEST... | mRNA 3'-end processing mRNA polyadenylation sno(s)RNA 3'-end processing termination of RNA polymerase II transcription, poly(A)-coupled mRNA cleavage and polyadenylation specificity factor complex; nucleus ATP binding magnesium ion binding poly(A) RNA polymerase activity RNA binding Saccharomyces cerevisiae 3D-structu... |
DNA damage response DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation pre-replicative complex assembly involved in nuclear cell cycle DNA replication premeiotic DNA replication | CMG complex; cytoplasm; DNA replication preinitiation complex; MCM complex; nuclear pre-replicative complex; nuclear replication fork; nucleoplasm; nucleus; replication fork protection complex | ATP binding ATP hydrolysis activity chromatin binding DNA replication origin binding helicase activity metal ion binding | Saccharomyces cerevisiae | 3D-structure ATP-binding Cell cycle DNA replication DNA-binding Helicase Hydrolase Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Zinc Zinc-finger | MSDNRRRRRE | MSDNRRRRREEDDSDSENELPPSSPQQHFRGGMNPVSSPIGSPDMINPEGDDNEVDDVPDIDEVEEQMNEVDLMDDNMYEDYAADHNRDRYDPDQVDDREQQELSLSERRRIDAQLNERDRLLRNVAYIDDEDEEQEGAAQLDEMGLPVQRRRRRRQYEDLENSDDDLLSDMDIDPLREELTLESLSNVKANSYSEWITQPNVSRTIARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSEIHVRISDFPTIYSLRELRESNLSSLVRV... | DNA damage response DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation pre-replicative complex assembly involved in nuclear cell cycle DNA replication premeiotic DNA replication CMG compl... |
fructose 6-phosphate metabolic process | cytoplasm | 6-phosphofructokinase activity diphosphate-fructose-6-phosphate 1-phosphotransferase activity metal ion binding | Propionibacterium freudenreichii subsp. shermanii | Cytoplasm Direct protein sequencing Glycolysis Kinase Magnesium Metal-binding Reference proteome Transferase | MVKKVALLTA | MVKKVALLTAGGFAPCLSSAIAELIKRYTEVSPETTLIGYRYGYEGLLKGDSLEFSPAVRAHYDRLFSFGGSPIGNSRVKLTNVKDLVARGLVASGDDPLKVAADQLIADGVDVLHTIGGDDTNTTAADLAAYLAQHDYPLTVVGLPKTIDNDIVPIRQSLGAWTAADEGARFAANVIAEHNAAPRELIIHEIMGRNCGYLAAETSRRYVAWLDAQQWLPEAGLDRRGWDIHALYVPEATIDLDAEAERLRTVMDEVGSVNIFISEGAGVPDIVAQMQATGQEVPTDAFGHVQLDKINPGAWFAKQFAERIGAGKTMVQK... | fructose 6-phosphate metabolic process cytoplasm 6-phosphofructokinase activity diphosphate-fructose-6-phosphate 1-phosphotransferase activity metal ion binding Propionibacterium freudenreichii subsp. shermanii Cytoplasm Direct protein sequencing Glycolysis Kinase Magnesium Metal-binding Reference proteome Transferase ... |
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