Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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DNA replication initiation DNA unwinding involved in DNA replication double-strand break repair via break-induced replication heterochromatin formation nuclear DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication premeiotic DNA replication regulation of DNA-templated DNA repli... | chromosome, telomeric region; CMG complex; cytoplasm; DNA replication preinitiation complex; MCM complex; nuclear pre-replicative complex; nuclear replication fork; nucleoplasm; nucleus; replication fork protection complex | ATP binding ATP hydrolysis activity chromatin binding DNA replication origin binding helicase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Cell cycle DNA replication DNA-binding Helicase Hydrolase Nucleotide-binding Nucleus Reference proteome | MSFDRPEIYS | MSFDRPEIYSAPVLQGESPNDDDNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENTSMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSG... | DNA replication initiation DNA unwinding involved in DNA replication double-strand break repair via break-induced replication heterochromatin formation nuclear DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication premeiotic DNA replication regulation of DNA-templated DNA repli... |
asymmetric cell division compound eye development germ-line stem cell population maintenance imaginal disc-derived wing morphogenesis long-term memory mesoderm development negative regulation of lamellocyte differentiation nervous system development neuroblast fate determination peripheral nervous system development po... | cytoplasm; cytosol; nucleus; perinuclear region of cytoplasm; plasma membrane | DNA binding phosphatidylinositol phosphate binding ubiquitin protein ligase activity ubiquitin-protein transferase activity zinc ion binding | Drosophila melanogaster | 3D-structure Alternative splicing Developmental protein Differentiation DNA-binding Metal-binding Neurogenesis Nucleus Phosphoprotein Reference proteome Repeat Zinc Zinc-finger | MGLSDIPANY | MGLSDIPANYMQGSHPHLTLHPQQQHHQNQQHLQHLQQMQQLHNAMPTPAQQAAQVLAMESNELLMSTKDKLSSKKKMHLLKKIKKRFGLVRRSPSSCPGPNNLPPLQFHSVHGDNIRISRDGTLARRFESFCRAITFSARPVRINERICVKFAEISNNWNGGIRFGFTSNDPVTLEGTLPKYACPDLTNRPGFWAKALHEQYCEKDNILYYYVNGAGDVIYGINNEEKGVILTGIDTRSLLWTVIDIYGNCTGIEFLDSRIYMYQQQPAAIPMATVPAQQQQMPQPAANASSALNSHHPHQQSRRSLPGHTAAIEHDLE... | asymmetric cell division compound eye development germ-line stem cell population maintenance imaginal disc-derived wing morphogenesis long-term memory mesoderm development negative regulation of lamellocyte differentiation nervous system development neuroblast fate determination peripheral nervous system development po... |
cell fate specification locomotion negative regulation of transcription by RNA polymerase II neuroblast fate determination regulation of axonogenesis regulation of DNA-templated transcription regulation of synapse structure or activity regulation of transcription by RNA polymerase II synapse assembly synaptic target re... | axon; nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding | Caenorhabditis elegans | Developmental protein Differentiation DNA-binding Homeobox Neurogenesis Nucleus Reference proteome Repressor Transcription Transcription regulation | MIGALHACVD | MIGALHACVDAEPKIINDIWADFWKSQINSVLLNPSDGSETYLASDNGKSTSSREQSTSPDDDNLLMNEDDGIALEDDNDTGESAAKRRRTRTNFSGWQLEELESAFEASHYPDVFMREALAMRLDLLESRVQVWFQNRRAKWRKREQNRNGSSEIKKDDGEQMETKALPTFPFSIDSILAVSRVPRGRRPNAKYPRVQACKNLSPFMIPLFPITQPGGNVIREKSPPLPTQQSQIVATNALTTVAELLKSV | cell fate specification locomotion negative regulation of transcription by RNA polymerase II neuroblast fate determination regulation of axonogenesis regulation of DNA-templated transcription regulation of synapse structure or activity regulation of transcription by RNA polymerase II synapse assembly synaptic target re... |
autocrine signaling negative regulation of catalytic activity negative regulation of endopeptidase activity negative regulation of JUN kinase activity negative regulation of peptidase activity negative regulation of proteolysis paracrine signaling positive regulation of cell migration positive regulation of cell popula... | azurophil granule lumen; cytoplasm; cytoplasmic vesicle; cytosol; extracellular exosome; extracellular region; extracellular space; nucleus; plasma membrane; vesicle | cysteine-type endopeptidase inhibitor activity protease binding serine-type endopeptidase inhibitor activity virus receptor activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Protease inhibitor Reference proteome Serine protease inhibitor | MNSLSEANTK | MNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADLSGMTGS... | autocrine signaling negative regulation of catalytic activity negative regulation of endopeptidase activity negative regulation of JUN kinase activity negative regulation of peptidase activity negative regulation of proteolysis paracrine signaling positive regulation of cell migration positive regulation of cell popula... |
cell redox homeostasis cellular response to oxidative stress removal of superoxide radicals | cytosol; mitochondrial intermembrane space; mitochondrion | ferrous iron binding thioredoxin-disulfide reductase (NADP) activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing Disulfide bond FAD Flavoprotein Mitochondrion NADP Oxidoreductase Phosphoprotein Redox-active center Reference proteome | MVHNKVTIIG | MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAEKYLTSLE | cell redox homeostasis cellular response to oxidative stress removal of superoxide radicals cytosol; mitochondrial intermembrane space; mitochondrion ferrous iron binding thioredoxin-disulfide reductase (NADP) activity Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Disulfide bond FAD Flavopr... |
cellular response to gravity microtubule cytoskeleton organization | cytosol; microtubule; nucleolus; plant-type cell wall; plasma membrane; plasmodesma; tubulin complex; vacuole | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Arabidopsis thaliana | Acetylation Alternative splicing Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Phosphoprotein Reference proteome | MRECISIHIG | MRECISIHIGQAGIQVGNACWELYCLEHGIQPDGQMPGDKTVGGGDDAFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLDRIRKLADNCTGLQGFLVFNAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTVYPSPQVSTSVVEPYNSVLSTHSLLEHTDVSILLDNEAIYDICRRSLNIERPTYTNLNRLVSQVISSLTASLRFDGALNVDVTEFQTNLVPYPRIHFMLSSYAPVISAEKAFHEQLSVAEITNSAFEPASMMAKCDPRHGKYMACCLMYR... | cellular response to gravity microtubule cytoskeleton organization cytosol; microtubule; nucleolus; plant-type cell wall; plasma membrane; plasmodesma; tubulin complex; vacuole GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton Arabidopsis thaliana Acetylation Alternative splicing C... |
microtubule-based process | chloroplast stroma; cytosol; microtubule; nucleus; plant-type cell wall; plant-type vacuole; plasma membrane; tubulin complex | GTP binding GTPase activity metal ion binding mRNA binding structural constituent of cytoskeleton | Arabidopsis thaliana | Cytoplasm Cytoskeleton GTP-binding Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MREILHIQGG | MREILHIQGGQCGNQIGSKFWEVICDEHGIDSTGRYSGDTADLQLERINVYYNEASGGRYVPRAVLMDLEPGTMDSIRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDAVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLSTPSFGDLNHLISATMSGVTCSLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYISLTVPELTQQMWDSKNMMCAADPRHGRYLTASAIFRG... | microtubule-based process chloroplast stroma; cytosol; microtubule; nucleus; plant-type cell wall; plant-type vacuole; plasma membrane; tubulin complex GTP binding GTPase activity metal ion binding mRNA binding structural constituent of cytoskeleton Arabidopsis thaliana Cytoplasm Cytoskeleton GTP-binding Magnesium Meta... |
microtubule-based process | cytosol; Golgi apparatus; microtubule; peroxisome; plant-type cell wall; plasma membrane; plasmodesma; tubulin complex; vacuole | GTP binding GTPase activity metal ion binding mRNA binding structural constituent of cytoskeleton | Arabidopsis thaliana | Cytoplasm Cytoskeleton GTP-binding Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MREILHIQGG | MREILHIQGGQCGNQIGSKFWEVVNLEHGIDQTGRYVGDSELQLERVNVYYNEASCGRYVPRAVLMDLEPGTMDSVRSGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMMTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLSTPSFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRNLTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGK... | microtubule-based process cytosol; Golgi apparatus; microtubule; peroxisome; plant-type cell wall; plasma membrane; plasmodesma; tubulin complex; vacuole GTP binding GTPase activity metal ion binding mRNA binding structural constituent of cytoskeleton Arabidopsis thaliana Cytoplasm Cytoskeleton GTP-binding Magnesium Me... |
microtubule-based process | chloroplast; cytosol; Golgi apparatus; microtubule; plant-type vacuole; plasma membrane; plasmodesma; tubulin complex | GTP binding GTPase activity metal ion binding mRNA binding structural constituent of cytoskeleton | Arabidopsis thaliana | Cytoplasm Cytoskeleton GTP-binding Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MREILHIQGG | MREILHIQGGQCGNQIGAKFWEVICGEHGIDQTGQSCGDTDLQLERINVYFNEASGGKYVPRAVLMDLEPGTMDSLRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMMTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLANPTFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYSALSVPELTQQMWDAKNMMCAADPRHGRYLTASAVFRGK... | microtubule-based process chloroplast; cytosol; Golgi apparatus; microtubule; plant-type vacuole; plasma membrane; plasmodesma; tubulin complex GTP binding GTPase activity metal ion binding mRNA binding structural constituent of cytoskeleton Arabidopsis thaliana Cytoplasm Cytoskeleton GTP-binding Magnesium Metal-bindin... |
amine metabolic process calcium-mediated signaling using intracellular calcium source cardiac neuron differentiation cell adhesion cell chemotaxis cell-cell adhesion in response to extracellular stimulus cell-matrix adhesion cellular response to amyloid-beta cellular response to glucose stimulus chorio-allantoic fusion... | alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex; apical part of cell; apical plasma membrane; cell periphery; cell surface; early endosome; endoplasmic reticulum; external side of plasma membrane; extracellular space; filopodium; Golgi apparatus; microvillus; podosome; sarcolemma | cell adhesion mediator activity cell adhesion molecule binding integrin binding primary amine oxidase activity | Mus musculus | Alternative splicing Cell adhesion Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Host-virus interaction Immunoglobulin domain Membrane Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix Ubl conjugation | MPVKMVAVLG | MPVKMVAVLGASTVLWILFAVSQAFKIEISPEYKTIAQIGDSMALTCSTTGCESPLFSWRTQIDSPLNAKVRTEGSKSVLTMEPVSFENEHSYLCTATCGSGKLERSIHVDIYSFPKDPEIQFSGPLEVGKPVTVKCLAPDIYPVYRLEIDLFKGDQLMNRQEFSSEEMTKSLETKSLEVTFTPVIEDIGKALVCRAKLHIDQIDSTLKERETVKELQVYISPRNTTISVHPSTRLQEGGAVTMTCSSEGLPAPEIFWGRKLDNEVLQLLSGNATLTLIAMRMEDSGVYVCEGVNLIGRDKAEVELVVQEKPFIVDISPG... | amine metabolic process calcium-mediated signaling using intracellular calcium source cardiac neuron differentiation cell adhesion cell chemotaxis cell-cell adhesion in response to extracellular stimulus cell-matrix adhesion cellular response to amyloid-beta cellular response to glucose stimulus chorio-allantoic fusion... |
amine metabolic process calcium-mediated signaling using intracellular calcium source cardiac neuron differentiation cell adhesion cell chemotaxis cell-cell adhesion in response to extracellular stimulus cell-matrix adhesion cellular response to amyloid-beta cellular response to glucose stimulus cellular response to tu... | alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex; apical part of cell; apical plasma membrane; cell periphery; cell surface; early endosome; endoplasmic reticulum; external side of plasma membrane; extracellular space; filopodium; Golgi apparatus; microvillus; podosome; sarcolemma | cell adhesion mediator activity cell adhesion molecule binding integrin binding primary amine oxidase activity | Rattus norvegicus | Cell adhesion Cell membrane Disulfide bond Glycoprotein Host-virus interaction Immunoglobulin domain Membrane Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix Ubl conjugation | MPVKMVAIFG | MPVKMVAIFGASTVLWILFAVSQAFKIEISPEYKTLAQIGDSMLLTCSTTGCESPSFSWRTQIDSPLNGKVKTEGAKSVLTMDPVSFENEHSYLCTATCNSGKLERGIQVDIYSFPKDPEIQFSGPLEVGKPVMVKCLAPDVYPIDRLEIELFKGDRLMKKQDFVDEMAKKSLETKSLEVIFTPVIEDIEKALVCRAKLYIDQTDSIPKERETVRELQVYTSPKNTEISVHPSTRLHEGAAVTMTCASEGLPAPEIFWSKKLDNGVLQLLSGNATLTLIAMRMEDSGIYVCEGVNLVGRDKTEVELIVQEKPFTVDISPG... | amine metabolic process calcium-mediated signaling using intracellular calcium source cardiac neuron differentiation cell adhesion cell chemotaxis cell-cell adhesion in response to extracellular stimulus cell-matrix adhesion cellular response to amyloid-beta cellular response to glucose stimulus cellular response to tu... |
actin filament organization actin nucleation muscle contraction myofibril assembly pointed-end actin filament capping positive regulation of actin filament polymerization | actin filament; cytoskeleton; cytosol; membrane; myofibril; sarcomere; striated muscle thin filament | actin binding tropomyosin binding | Homo sapiens | 3D-structure Actin-binding Alternative splicing Cytoplasm Cytoskeleton Disease variant Phosphoprotein Reference proteome Repeat | MSRVAKYRRQ | MSRVAKYRRQVSEDPDIDSLLETLSPEEMEELEKELDVVDPDGSVPVGLRQRNQTEKQSTGVYNREAMLNFCEKETKKLMQREMSMDESKQVETKTDAKNGEERGRDASKKALGPRRDSDLGKEPKRGGLKKSFSRDRDEAGGKSGEKPKEEKIIRGIDKGRVRAAVDKKEAGKDGRGEERAVATKKEEEKKGSDRNTGLSRDKDKKREEMKEVAKKEDDEKVKGERRNTDTRKEGEKMKRAGGNTDMKKEDEKVKRGTGNTDTKKDDEKVKKNEPLHEKEAKDDSKTKTPEKQTPSGPTKPSEGPAKVEEEAAPSIFDE... | actin filament organization actin nucleation muscle contraction myofibril assembly pointed-end actin filament capping positive regulation of actin filament polymerization actin filament; cytoskeleton; cytosol; membrane; myofibril; sarcomere; striated muscle thin filament actin binding tropomyosin binding Homo sapiens 3... |
positive regulation of transcription by RNA polymerase II regulation of translational termination translational elongation | cytoplasm; cytoplasmic stress granule; eukaryotic translation elongation factor 1 complex; nucleus; ribosome | calcium ion binding core promoter sequence-specific DNA binding DNA-binding transcription factor activity guanyl-nucleotide exchange factor activity phospholipid binding translation elongation factor activity | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Direct protein sequencing Elongation factor Nucleus Phosphoprotein Protein biosynthesis Reference proteome | MSQGTLYANF | MSQGTLYANFRIRTWVPRGLVKALKLDVKVVTPDAAAEQFARDFPLKKVPAFVGPKGYKLTEAMAINYYLVKLSQDDKMKTQLLGADDDLNAQAQIIRWQSLANSDLCIQIANTIVPLKGGAPYNKKSVDSAMDAVDKIVDIFENRLKNYTYLATENISLADLVAASIFTRYFESLFGTEWRAQHPAIVRWFNTVRASPFLKDEYKDFKFADKPLSPPQKKKEKKAPAAAPAASKKKEEAKPAATETETSSKKPKHPLELLGKSTFVLDDWKRKYSNEDTRPVALPWFWEHYNPEEYSLWKVTYKYNDELTLTFMSNNLV... | positive regulation of transcription by RNA polymerase II regulation of translational termination translational elongation cytoplasm; cytoplasmic stress granule; eukaryotic translation elongation factor 1 complex; nucleus; ribosome calcium ion binding core promoter sequence-specific DNA binding DNA-binding transcriptio... |
extrinsic apoptotic signaling pathway via death domain receptors immune response necroptotic signaling pathway negative regulation of protein-containing complex disassembly positive regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction positive regulation of extrinsic apoptotic ... | cell surface; extracellular space; plasma membrane | cytokine activity tumor necrosis factor receptor binding | Equus caballus | Cell membrane Cytokine Disulfide bond Glycoprotein Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Secreted Signal-anchor Transmembrane Transmembrane helix | MSTESMIRDV | MSTESMIRDVELAEEELAKKAGGPQGSRRCLCLSLFSFLLVAGATTLFCLLHFGVIGPQREEQLPNAFQSINPLAQTLRSSSRTPSDKPVAHVVANPQAEGQLQWLSGRANALLANGVKLTDNQLVVPLDGLYLIYSQVLFKGQGCPSTHVLLTHTISRLAVSYPSKVNLLSAIKSPCHTESPEQAEAKPWYEPIYLGGVFQLEKGDQLSAEINQPNYLDFAESGQVYFGIIAL | extrinsic apoptotic signaling pathway via death domain receptors immune response necroptotic signaling pathway negative regulation of protein-containing complex disassembly positive regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction positive regulation of extrinsic apoptotic ... |
anterior/posterior pattern specification apoptotic process cardiac muscle tissue development cardioblast differentiation determination of genital disc primordium dorsal vessel heart proper cell fate commitment genital disc anterior/posterior pattern formation genitalia development germ cell migration gonad development ... | nucleus; polytene chromosome band; RNA polymerase II transcription regulator complex; transcription regulator complex | cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Drosophila melanogaster | 3D-structure Alternative splicing Developmental protein DNA-binding Homeobox Nucleus Reference proteome | MSKFVFDSML | MSKFVFDSMLPKYPQFQPFISSHHLTTTPPNSSSAAVAAALAAAAASASASVSASSSSNNNSSNTIAGSNTSNTNNSSSSPSSSSNNNSNLNLSGGSLSPSHLSQHLGQSPHSPVSSSSPFQQHHPQVQQQHLNHQQQQHLHHQQQQHHHQYSSLSAALQLQQQQHHISKLAAAAVASHGHAHQQLLLTPPSAGNSQAGDSSCSPSPSASGSSSLHRSLNDNSPGSASASASASAASSVAAAAAAAAAAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPASASAQFAQFYQHA... | anterior/posterior pattern specification apoptotic process cardiac muscle tissue development cardioblast differentiation determination of genital disc primordium dorsal vessel heart proper cell fate commitment genital disc anterior/posterior pattern formation genitalia development germ cell migration gonad development ... |
DNA replication RNA processing | cytosol; nucleus; ribonucleoprotein complex | double-stranded DNA binding mRNA 3'-UTR binding poly(A) binding poly(U) RNA binding RNA binding single-stranded DNA binding | Homo sapiens | 3D-structure Alternative splicing DNA replication DNA-binding Nucleus Phosphoprotein Reference proteome Repeat RNA-binding | MGKVWKQQMY | MGKVWKQQMYPQYATYYYPQYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIPNGRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPYSIATNRMITQTSITPYIASPVSAYQVQSPSWMQPQPYILQHPGAV... | DNA replication RNA processing cytosol; nucleus; ribonucleoprotein complex double-stranded DNA binding mRNA 3'-UTR binding poly(A) binding poly(U) RNA binding RNA binding single-stranded DNA binding Homo sapiens 3D-structure Alternative splicing DNA replication DNA-binding Nucleus Phosphoprotein Reference proteome Repe... |
apoptotic signaling pathway cellular response to mechanical stimulus DNA damage response DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest ectopic germ cell programmed cell death extrinsic apoptotic signaling pathway in absence of ligand intrinsic apoptotic signaling pathway ... | cytoplasm; endopeptidase complex; nucleolus; nucleus | cysteine-type endopeptidase activity cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway cysteine-type endopeptidase activity involved in execution phase of apoptosis identical protein binding protein domain specific binding | Mus musculus | Acetylation Apoptosis Hydrolase Phosphoprotein Protease Reference proteome Thiol protease Zymogen | MAAPSGRSQS | MAAPSGRSQSSLHRKGLMAADRRSRILAVCGMHPDHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKGGSFSQNVELLNLLPKRGPQAFDAFCEALRETRQGHLEDLLLTTLSDIQHVLPPLSCDYDTSLPFSVCESCPPHKQLRLSTDATEHSLDNGDGPPCLLVKPCTPEFYQAHYQLAYRLQSQPRGLALVLSNVHFTGEKDLEFRSGGDVDHTTLVTLFKLLGYNVHVLHDQTAQEMQEKLQNFAQLPAHRVTDSCVVALLSHGVEGGIYGVDGKLLQLQEVFRLFDNANCPSLQNKPKMFFIQAC... | apoptotic signaling pathway cellular response to mechanical stimulus DNA damage response DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest ectopic germ cell programmed cell death extrinsic apoptotic signaling pathway in absence of ligand intrinsic apoptotic signaling pathway ... |
modification-dependent protein catabolic process protein localization protein neddylation regulation of proteolysis regulation of transcription by RNA polymerase II response to organic cyclic compound | cytosol; nucleoplasm; nucleus | protein tag activity ubiquitin protein ligase binding | Mus musculus | Acetylation Isopeptide bond Nucleus Reference proteome Ubl conjugation pathway | MLIKVKTLTG | MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGGGGLGQ | modification-dependent protein catabolic process protein localization protein neddylation regulation of proteolysis regulation of transcription by RNA polymerase II response to organic cyclic compound cytosol; nucleoplasm; nucleus protein tag activity ubiquitin protein ligase binding Mus musculus Acetylation Isopeptide... |
cell fate determination cellular response to amino acid starvation endoplasmic reticulum unfolded protein response gluconeogenesis negative regulation of DNA-templated transcription negative regulation of ERK1 and ERK2 cascade negative regulation of transcription by RNA polymerase II positive regulation of cell populat... | CHOP-ATF3 complex; nucleolus; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific identical protein binding protein heterodimerizati... | Rattus norvegicus | DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation | MMLQHPGQVS | MMLQHPGQVSASEVSATAIVPCLSPPGSLVFEDFANLTPFVKEELRFAIQNKHLCHRMSSALESVTINNRPLEMSVTKSEVAPEEDERKRRRRERNKIAAAKCRNKKKEKTECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFIQQIKEGTLQS | cell fate determination cellular response to amino acid starvation endoplasmic reticulum unfolded protein response gluconeogenesis negative regulation of DNA-templated transcription negative regulation of ERK1 and ERK2 cascade negative regulation of transcription by RNA polymerase II positive regulation of cell populat... |
angiogenesis cellular response to fluid shear stress cellular response to glucose stimulus cellular response to hepatocyte growth factor stimulus cellular response to hypoxia cellular response to lipopolysaccharide cellular response to organic substance cellular response to staurosporine embryo implantation fibrinolysi... | cell surface; extracellular space; protein complex involved in cell-matrix adhesion; serine protease inhibitor complex; serine-type endopeptidase complex | peptidase activity serine-type endopeptidase activity | Rattus norvegicus | Disulfide bond EGF-like domain Hydrolase Kringle Phosphoprotein Plasminogen activation Protease Reference proteome Secreted Serine protease Signal Zymogen | MRVWLASLFL | MRVWLASLFLCALVANSEGGSELEASDESNCGCQNGGVCVSYKYFSSIRRCSCPKKFKGEHCEIDTSKTCYHGNGQSYRGKANTDTKGRPCLAWNSPAVLQQTYNAHRSDALSLGLGKHNYCRNPDNQRRPWCYVQIGLKQFVQECMVQDCSLSKKPSSTVDQQGFQCGQKALRPRFKIVGGEFTVVENQPWFAAIYLKNKGGSPPSFKCGGSLISPCWVASATHCFVNQPKKEEYVVYLGQSKRNSYNPGEMKFEVEQLILHEDFSDETLAFHNDIALLKIRTSTGQCAQPSRTIQTICLPPRFGDAPFGSDCEITGFG... | angiogenesis cellular response to fluid shear stress cellular response to glucose stimulus cellular response to hepatocyte growth factor stimulus cellular response to hypoxia cellular response to lipopolysaccharide cellular response to organic substance cellular response to staurosporine embryo implantation fibrinolysi... |
determination of adult lifespan gluconeogenesis glucose homeostasis glyceraldehyde-3-phosphate biosynthetic process glyceraldehyde-3-phosphate metabolic process glycerol catabolic process glycolytic process nervous system process response to mechanical stimulus | cytosol; M band; Z disc | protein homodimerization activity triose-phosphate isomerase activity | Drosophila melanogaster | Alternative splicing Direct protein sequencing Gluconeogenesis Glycolysis Isomerase Reference proteome | MSRKFCVGGN | MSRKFCVGGNWKMNGDQKSIAEIAKTLSSAALDPNTEVVIGCPAIYLMYARNLLPCELGLAGQNAYKVAKGAFTGEISPAMLKDIGADWVILGHSERRAIFGESDALIAEKAEHALAEGLKVIACIGETLEEREAGKTNEVVARQMCAYAQKIKDWKNVVVAYEPVWAIGTGQTATPDQAQEVHAFLRQWLSDNISKEVSASLRIQYGGSVTAANAKELAKKPDIDGFLVGGASLKPEFVDIINARQ | determination of adult lifespan gluconeogenesis glucose homeostasis glyceraldehyde-3-phosphate biosynthetic process glyceraldehyde-3-phosphate metabolic process glycerol catabolic process glycolytic process nervous system process response to mechanical stimulus cytosol; M band; Z disc protein homodimerization activity ... |
G1/S transition of mitotic cell cycle phosphorylation regulation of G2/M transition of mitotic cell cycle regulation of gene expression regulation of meiotic cell cycle response to organic substance signal transduction | cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus | ATP binding cyclin binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity | Oryza sativa subsp. japonica | ATP-binding Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MEQYEKEEKI | MEQYEKEEKIGEGTYGVVYRARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMHHGNIVRLHDVIHSEKRIYLVFEYLDLDLKKFMDSCPEFAKNPTLIKSYLYQILRGVAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSRQYSTPVDMWSVGCIFAEMVNQKPLFPGDSEIDELFKIFRVLGTPNEQSWPGVSSLPDYKSAFPKWQAQDLATIVPTLDPAGLDLLSKMLRYEPNKRITARQALEHEYFKDLEMVQ | G1/S transition of mitotic cell cycle phosphorylation regulation of G2/M transition of mitotic cell cycle regulation of gene expression regulation of meiotic cell cycle response to organic substance signal transduction cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus ATP binding cyclin binding cyc... |
G1/S transition of mitotic cell cycle phosphorylation regulation of G2/M transition of mitotic cell cycle regulation of gene expression regulation of meiotic cell cycle response to organic substance signal transduction | cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus; NuRD complex | ATP binding cyclin binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity | Oryza sativa subsp. japonica | ATP-binding Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MEQYEKVEKI | MEQYEKVEKIGEGTYGVVYKGKHRHTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVRLQDVVHKEKCIYLVFEYLDLDLKKHMDSSPDFKNHRIVKSFLYQILRGIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGARHYSTPVDMWSVGCIFAEMVNQKPLFPGDSEIDELFKIFSIMGTPNEETWPGVASLPDYISTFPKWPSVDLATVVPTLDSSGLDLLSKMLRLDPSKRINARAALEHEYFKDLEVA | G1/S transition of mitotic cell cycle phosphorylation regulation of G2/M transition of mitotic cell cycle regulation of gene expression regulation of meiotic cell cycle response to organic substance signal transduction cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus; NuRD complex ATP binding cycl... |
cell cycle cell division phosphorylation positive regulation of transcription by RNA polymerase II | cytoplasm; nucleus; transcription factor TFIIK complex | ATP binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity | Oryza sativa subsp. japonica | ATP-binding Cell cycle Cell division Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MASGDGGDDA | MASGDGGDDAGVKRVADRYLKREVLGEGTYGVVFKAVDTKTGNTVAIKKIRLGKYKEGVNFTALREIKLLKELKDSNIIELIDAFPYKGNLHLVFEFMETDLEAVIRDRNIVLSPADTKSYIQMMLKGLAFCHKKWVLHRDMKPNNLLIGADGQLKLADFGLARIFGSPERNFTHQVFARWYRAPELLFGTKQYGSAVDIWAAGCIFAELLLRRPFLQGSSDIDQLGKIFAAFGTPKSSQWPDMVYLPDYVEYQFVSAPPLRSLFPMASDDALDLLSRMFTYDPKARITAQQALEHRYFLSVPAPTKPSQLPRPPPKGDS... | cell cycle cell division phosphorylation positive regulation of transcription by RNA polymerase II cytoplasm; nucleus; transcription factor TFIIK complex ATP binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity Oryza s... |
anatomical structure regression axon guidance cell fate commitment dorsal/ventral lineage restriction, imaginal disc dorsal/ventral pattern formation, imaginal disc haltere morphogenesis imaginal disc-derived leg segmentation imaginal disc-derived wing morphogenesis larval somatic muscle development leg disc developmen... | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Drosophila melanogaster | Alternative splicing Developmental protein DNA-binding Homeobox LIM domain Metal-binding Nucleus Reference proteome Repeat Zinc | MGVCTEERPV | MGVCTEERPVMHWQQSARFLGPGAREKSPTPPVAHQGSNQCGSAAGANNNHPLFRACSSSSCPDICDHSTKPFGNAYGTESFRSYETADRATFEDSAAKFSISRSRTDCTEVSDETTSGISFKTEPFGPPSSPESTSDSKITRNLDDCSGCGRQIQDRFYLSAVEKRWHASCLQCYACRQPLERESSCYSRDGNIYCKNDYYSFFGTRRCSRCLASISSNELVMRARNLVFHVNCFCCTVCHTPLTKGDQYGIIDALIYCRTHYSIAREGDTASSSMSATYPYSAQFGSPHNDSSSPHSDPSRSIVPTGIFVPASHVING... | anatomical structure regression axon guidance cell fate commitment dorsal/ventral lineage restriction, imaginal disc dorsal/ventral pattern formation, imaginal disc haltere morphogenesis imaginal disc-derived leg segmentation imaginal disc-derived wing morphogenesis larval somatic muscle development leg disc developmen... |
anterior/posterior pattern specification axis specification cell migration involved in gastrulation chordate embryonic development muscle organ development nephron tubule development neurogenesis notochord development positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymer... | nucleus; transcription regulator complex | DNA-binding transcription factor activity, RNA polymerase II-specific sequence-specific DNA binding transcription coregulator binding zinc ion binding | Xenopus laevis | Activator Developmental protein Differentiation DNA-binding Gastrulation Homeobox LIM domain Metal-binding Neurogenesis Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc | MVHCAGCERP | MVHCAGCERPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLNNNNAAKENSFISVTGSDPSLSPESQDPLQDDAKDSESANVSDKEAGINENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFAFYGDYQSEYYGPGSNYDFFPQGPPSSQAQTPVDLPFVPSSVPAG... | anterior/posterior pattern specification axis specification cell migration involved in gastrulation chordate embryonic development muscle organ development nephron tubule development neurogenesis notochord development positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymer... |
phosphorylation regulation of early endosome to late endosome transport regulation of Golgi inheritance regulation of stress-activated MAPK cascade | centrosome; early endosome; focal adhesion; late endosome; membrane; mitochondrion; nucleus | ATP binding MAP kinase kinase activity protein serine kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity | Oryctolagus cuniculus | 3D-structure ATP-binding Cytoplasm Cytoskeleton Direct protein sequencing Kinase Membrane Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Tyrosine-protein kinase | MPKKKPTPIQ | MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNE... | phosphorylation regulation of early endosome to late endosome transport regulation of Golgi inheritance regulation of stress-activated MAPK cascade centrosome; early endosome; focal adhesion; late endosome; membrane; mitochondrion; nucleus ATP binding MAP kinase kinase activity protein serine kinase activity protein se... |
defense response to Gram-negative bacterium negative regulation of gene expression translational elongation | cytosol; ribonucleoprotein complex | GTP binding GTPase activity ribosome binding translation elongation factor activity | Caenorhabditis elegans | Alternative splicing Cytoplasm Elongation factor GTP-binding Hydrolase Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome | MVNFTVDEIR | MVNFTVDEIRALMDRKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGSKAGETRFTDTRKDEQERCITIKSTAISLFFELEKKDLEFVKGENQFETVEVDGKKEKYNGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLFMNKMDRALLELQLGAEELFQTFQRIVENINVIIATYGDDDGPMGPIMVDPSIGNVGFGSGLHGWAFTLKQFAEMYAGKFGVQVDKLMKNLWGDRFFDLKTKKWSSTQTDESKRGFCQFVLDPIFMVFDAVMNIKKDKTAALVEKLGIKLAND... | defense response to Gram-negative bacterium negative regulation of gene expression translational elongation cytosol; ribonucleoprotein complex GTP binding GTPase activity ribosome binding translation elongation factor activity Caenorhabditis elegansAlternative splicing Cytoplasm Elongation factor GTP-binding Hydrolase ... |
cellular response to heat cellular response to ionizing radiation cytoplasmic translational elongation positive regulation of transcription by RNA polymerase II translational elongation | cytoplasm; cytosol; eukaryotic translation elongation factor 1 complex; fibrillar center; nucleoplasm; nucleus | cadherin binding DNA binding DNA-binding transcription factor binding guanyl-nucleotide exchange factor activity heat shock protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding translation elongation factor activity translation factor activity, RNA binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Direct protein sequencing DNA-binding Elongation factor Nucleus Phosphoprotein Protein biosynthesis Reference proteome Transcription Transcription regulation | MATNFLAHEK | MATNFLAHEKIWFDKFKYDDAERRFYEQMNGPVAGASRQENGASVILRDIARARENIQKSLAGSSGPGASSGTSGDHGELVVRIASLEVENQSLRGVVQELQQAISKLEARLNVLEKSSPGHRATAPQTQHVSPMRQVEPPAKKPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDVKPWDDETDMAQLEACVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEEITKFEEHVQSVDIAAFNKI | cellular response to heat cellular response to ionizing radiation cytoplasmic translational elongation positive regulation of transcription by RNA polymerase II translational elongation cytoplasm; cytosol; eukaryotic translation elongation factor 1 complex; fibrillar center; nucleoplasm; nucleus cadherin binding DNA bi... |
acute-phase response male gonad development negative regulation of bone mineralization negative regulation of cell growth negative regulation of insulin receptor signaling pathway ossification positive regulation of bone resorption positive regulation of phagocytosis protein-containing complex assembly regulation of in... | collagen-containing extracellular matrix; extracellular matrix; extracellular region; extracellular space; Golgi apparatus; protein-containing complex | cysteine-type endopeptidase inhibitor activity endopeptidase inhibitor activity receptor signaling protein tyrosine kinase inhibitor activity | Mus musculus | Direct protein sequencing Disulfide bond Glycoprotein Phosphoprotein Reference proteome Repeat Secreted Signal | MKSLVLLLCF | MKSLVLLLCFAQLWGCQSAPQGTGLGFRELACDDPEAEQVALLAVDYLNNHLLQGFKQVLNQIDKVKVWSRRPFGVVYEMEVDTLETTCHALDPTPLANCSVRQLTEHAVEGDCDFHILKQDGQFRVMHTQCHSTPDSAEDVRKLCPRCPLLTPFNDTNVVHTVNTALAAFNTQNNGTYFKLVEISRAQNVPLPVSTLVEFVIAATDCTAKEVTDPAKCNLLAEKQHGFCKANLMHNLGGEEVSVACKLFQTQPQPANANAVGPVPTANAALPADPPASVVVGPVVVPRGLSDHRTYHDLRHAFSPVASVESASGETLHS... | acute-phase response male gonad development negative regulation of bone mineralization negative regulation of cell growth negative regulation of insulin receptor signaling pathway ossification positive regulation of bone resorption positive regulation of phagocytosis protein-containing complex assembly regulation of in... |
peptide pheromone maturation protein farnesylation protein geranylgeranylation | CAAX-protein geranylgeranyltransferase complex; cytoplasm; protein farnesyltransferase complex | CAAX-protein geranylgeranyltransferase activity protein farnesyltransferase activity protein geranylgeranyltransferase activity | Saccharomyces cerevisiae | Cytoplasm Magnesium Prenyltransferase Reference proteome Repeat Transferase | MEEYDYSDVK | MEEYDYSDVKPLPIETDLQDELCRIMYTEDYKRLMGLARALISLNELSPRALQLTAEIIDVAPAFYTIWNYRFNIVRHMMSESEDTVLYLNKELDWLDEVTLNNPKNYQIWSYRQSLLKLHPSPSFKRELPILKLMIDDDSKNYHVWSYRKWCCLFFSDFQHELAYASDLIETDIYNNSAWTHRMFYWVNAKDVISKVELADELQFIMDKIQLVPQNISPWTYLRGFQELFHDRLQWDSKVVDFATTFIGDVLSLPIGSPEDLPEIESSYALEFLAYHWGADPCTRDNAVKAYSLLAIKYDPIRKNLWHHKINNLN | peptide pheromone maturation protein farnesylation protein geranylgeranylation CAAX-protein geranylgeranyltransferase complex; cytoplasm; protein farnesyltransferase complex CAAX-protein geranylgeranyltransferase activity protein farnesyltransferase activity protein geranylgeranyltransferase activity Saccharomyces cere... |
ergosterol biosynthetic process farnesyl diphosphate metabolic process isoprenoid biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane; membrane; mitochondrial outer membrane; mitochondrion | farnesyl-diphosphate farnesyltransferase activity squalene synthase activity | Saccharomyces cerevisiae | Endoplasmic reticulum Isoprene biosynthesis Lipid biosynthesis Lipid metabolism Magnesium Membrane Microsome Multifunctional enzyme NADP Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transferase Transmembrane Transmembrane helix | MGKLLQLALH | MGKLLQLALHPVEMKAALKLKFCRTPLFSIYDQSTSPYLLHCFELLNLTSRSFAAVIRELHPELRNCVTLFYLILRALDTIEDDMSIEHDLKIDLLRHFHEKLLLTKWSFDGNAPDVKDRAVLTDFESILIEFHKLKPEYQEVIKEITEKMGNGMADYILDENYNLNGLQTVHDYDVYCHYVAGLVGDGLTRLIVIAKFANESLYSNEQLYESMGLFLQKTNIIRDYNEDLVDGRSFWPKEIWSQYAPQLKDFMKPENEQLGLDCINHLVLNALSHVIDVLTYLAGIHEQSTFQFCAIPQVMAIATLALVFNNREVLHGN... | ergosterol biosynthetic process farnesyl diphosphate metabolic process isoprenoid biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane; membrane; mitochondrial outer membrane; mitochondrion farnesyl-diphosphate farnesyltransferase activity squalene synthase activity Saccharomyces cerevisiae Endop... |
cell-substrate adhesion fungal-type cell wall organization glucan catabolic process glucan metabolic process single-species biofilm formation in or on host organism single-species biofilm formation on inanimate substrate | cell surface; extracellular region; extracellular vesicle | cell adhesion molecule binding glucan exo-1,3-beta-glucosidase activity transferase activity | Candida albicans | 3D-structure Cell adhesion Cell wall Cell wall biogenesis/degradation Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycosidase Hydrolase Reference proteome Secreted Signal Transferase Virulence Zymogen | MQLSFILTSS | MQLSFILTSSVFILLLEFVKASVISNPFKPNGNLKFKRGGGHNVAWDYDNNVIRGVNLGGWFVLEPYMTPSLFEPFQNGNDQSGVPVDEYHWTQTLGKEAASRILQKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNFLTVAEGQWNVVVDHHHYQVFSGGELSRNINDHISVACNWGWDAK... | cell-substrate adhesion fungal-type cell wall organization glucan catabolic process glucan metabolic process single-species biofilm formation in or on host organism single-species biofilm formation on inanimate substrate cell surface; extracellular region; extracellular vesicle cell adhesion molecule binding glucan exo... |
proteolysis | plasma membrane | peptidase activity | Treponema pallidum | 3D-structure Cell inner membrane Cell membrane Direct protein sequencing Hydrolase Lipoprotein Membrane Palmitate Protease Reference proteome Signal | MKVKYALLSA | MKVKYALLSAGALQLLVVGCGSSHHETHYGYATLSYADYWAGELGQSRDVLLAGNAEADRAGDLDAGMFDAVSRATHGHGAFRQQFQYAVEVLGEKVLSKQETEDSRGRKKWEYETDPSVTKMVRASASFQDLGEDGEIKFEAVEGAVALADRASSFMVDSEEYKITNVKVHGMKFVPVAVPHELKGIAKEKFHFVEDSRVTENTNGLKTMLTEDSFSARKVSSMESPHDLVVDTVGTGYHSRFGSDAEASVMLKRADGSELSHREFIDYVMNFNTVRYDYYGDDASYTNLMASYGTKHSADSWWKTGRVPRISCGINYG... | proteolysis plasma membrane peptidase activity Treponema pallidum 3D-structure Cell inner membrane Cell membrane Direct protein sequencing Hydrolase Lipoprotein Membrane Palmitate Protease Reference proteome Signal MKVKYALLSA MKVKYALLSAGALQLLVVGCGSSHHETHYGYATLSYADYWAGELGQSRDVLLAGNAEADRAGDLDAGMFDAVSRATHGHGAFRQQFQYAVEVLG... |
defense response to bacterium defense response to virus interleukin-27-mediated signaling pathway negative regulation of viral genome replication nucleobase-containing compound metabolic process positive regulation of interferon-beta production positive regulation of tumor necrosis factor production regulation of lacta... | cytoplasm; cytosol; intracellular membrane-bounded organelle; membrane; nucleoplasm; perinuclear region of cytoplasm | 2'-5'-oligoadenylate synthetase activity ATP binding double-stranded RNA binding metal ion binding | Homo sapiens | Acetylation Alternative splicing Antiviral defense ATP-binding Cytoplasm Direct protein sequencing Glycoprotein Immunity Innate immunity Lipoprotein Magnesium Metal-binding Myristate Nucleotide-binding Nucleotidyltransferase Reference proteome Repeat RNA-binding Transferase | MGNGESQLSS | MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLT... | defense response to bacterium defense response to virus interleukin-27-mediated signaling pathway negative regulation of viral genome replication nucleobase-containing compound metabolic process positive regulation of interferon-beta production positive regulation of tumor necrosis factor production regulation of lacta... |
carbohydrate metabolic process | vacuole | glucosinolate glucohydrolase activity metal ion binding thioglucosidase activity | Sinapis alba | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Metal-binding Vacuole Zinc | DEEITCQENL | DEEITCQENLPFTCGNTDALNSSSFSSDFIFGVASSAYQIEGTIGRGLNIWDGFTHRYPNKSGPDHGNGDTTCDSFSYWQKDIDVLDELNATGYRFSIAWSRIIPRGKRSRGVNEKGIDYYHGLISGLIKKGITPFVTLFHWDLPQTLQDEYEGFLDPQIIDDFKDYADLCFEEFGDSVKYWLTINQLYSVPTRGYGSALDAPGRCSPTVDPSCYAGNSSTEPYIVAHHQLLAHAKVVDLYRKNYTHQGGKIGPTMITRWFLPYNDTDRHSIAATERMKEFFLGWFMGPLTNGTYPQIMIDTVGERLPSFSPEESNLVKG... | carbohydrate metabolic process vacuole glucosinolate glucohydrolase activity metal ion binding thioglucosidase activity Sinapis alba 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Metal-binding Vacuole Zinc DEEITCQENL DEEITCQENLPFTCGNTDALNSSSFSSDFIFGVASSAYQIEGTIGRGLNIWDGFTHRYP... |
peptide catabolic process peptide metabolic process proteolysis | cytosol | metallopeptidase activity protein homodimerization activity tripeptide aminopeptidase activity zinc ion binding | Escherichia coli | 3D-structure Aminopeptidase Cytoplasm Hydrolase Metal-binding Metalloprotease Protease Reference proteome Zinc | MDKLLERFLN | MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEEMGLINVTLSEKGTLMATLPANVPGDIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKKIPHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIVGNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVERADMHYIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYY... | peptide catabolic process peptide metabolic process proteolysis cytosol metallopeptidase activity protein homodimerization activity tripeptide aminopeptidase activity zinc ion binding Escherichia coli 3D-structure Aminopeptidase Cytoplasm Hydrolase Metal-binding Metalloprotease Protease Reference proteome Zinc MDKLLERF... |
chitin-based larval cuticle pattern formation dorsal/ventral pattern formation larval chitin-based cuticle development positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II salivary gland development | chromatin; mitochondrion; nucleolus; nucleus; transcription regulator complex | cAMP response element binding chromatin binding cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific sequence-specific DNA binding | Drosophila melanogaster | Activator DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MEFYDGDLKD | MEFYDGDLKDIWDSDLDPESLKISPDHDMHDWLFDRDVKDPTVILNDKLISDALLNGTQPIKTEHSYSLSSDVDSLPDSPKSLQAKIEDMDDECFPAISPKTATNGRVTIDPKYLTFHVPPTHATPISRLSSNPALNTSVADLTRSSGLQSLQAHQPHHGSGSSHVVVANLEHFQLPQHLYDNDCSSSVSSLRDGSMSPDICSDIEIDESAIKDEPMSPDSSCPASPTSQASSSQHQLSLNLAHLQSEMLFEPKHCGLLLTASSNSNNSLIKSQQRQQQILGQDNLLMAKMEIKSEKQSTSNSSDKSHAHGYGIPLTPPS... | chitin-based larval cuticle pattern formation dorsal/ventral pattern formation larval chitin-based cuticle development positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II salivary gland development chromatin; mitoc... |
lactose biosynthetic process | extracellular region; protein-containing complex | calcium ion binding lactose synthase activity lysozyme activity | Mus musculus | 3D-structure Calcium Disulfide bond Glycoprotein Lactose biosynthesis Metal-binding Milk protein Reference proteome Secreted Signal | MMHFVPLFLV | MMHFVPLFLVCILSLPAFQATELTKCKVSHAIKDIDGYQGISLLEWACVLFHTSGYDTQAVVNDNGSTEYGLFQISDRFWCKSSEFPESENICGISCDKLLDDELDDDIACAKKILAIKGIDYWKAYKPMCSEKLEQWRCEKP | lactose biosynthetic process extracellular region; protein-containing complex calcium ion binding lactose synthase activity lysozyme activity Mus musculus 3D-structure Calcium Disulfide bond Glycoprotein Lactose biosynthesis Metal-binding Milk protein Reference proteome Secreted Signal MMHFVPLFLV MMHFVPLFLVCILSLPAFQATE... |
ganglioside catabolic process oligosaccharide catabolic process | cytoplasm; intracellular membrane-bounded organelle; membrane | exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity exo-alpha-sialidase activity | Salmonella typhimurium | 3D-structure Direct protein sequencing Disulfide bond Glycosidase Hydrolase Reference proteome Repeat | MTVEKSVVFK | MTVEKSVVFKAEGEHFTDQKGNTIVGSGSGGTTKYFRIPAMCTTSKGTIVVFADARHNTASDQSFIDTAAARSTDGGKTWNKKIAIYNDRVNSKLSRVMDPTCIVANIQGRETILVMVGKWNNNDKTWGAYRDKAPDTDWDLVLYKSTDDGVTFSKVETNIHDIVTKNGTISAMLGGVGSGLQLNDGKLVFPVQMVRTKNITTVLNTSFIYSTDGITWSLPSGYCEGFGSENNIIEFNASLVNNIRNSGLRRSFETKDFGKTWTEFPPMDKKVDNRNHGVQGSTITIPSGNKLVAAHSSAQNKNNDYTRSDISLYAHNLY... | ganglioside catabolic process oligosaccharide catabolic process cytoplasm; intracellular membrane-bounded organelle; membrane exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity exo-alpha-sialidase activity Salmonella typhimurium 3D-structure Direct protein sequen... |
cell adhesion mediated by integrin cell migration cell-matrix adhesion endodermal cell differentiation extracellular matrix organization immune response liver regeneration negative regulation of fibrinolysis oligodendrocyte differentiation positive regulation of cell-substrate adhesion positive regulation of peptidyl-t... | basement membrane; collagen-containing extracellular matrix; endoplasmic reticulum; extracellular matrix; extracellular space; Golgi lumen; intracellular membrane-bounded organelle; peptidase inhibitor complex; protein complex involved in cell-matrix adhesion; rough endoplasmic reticulum lumen | collagen binding extracellular matrix binding heparin binding identical protein binding integrin binding polysaccharide binding scavenger receptor activity | Mus musculus | Cell adhesion Direct protein sequencing Disulfide bond Glycoprotein Heparin-binding Phosphoprotein Reference proteome Repeat Secreted Signal Sulfation | MAPLRPFFIL | MAPLRPFFILALVAWVSLADQESCKGRCTQGFMASKKCQCDELCTYYQSCCADYMEQCKPQVTRGDVFTMPEDDYWSYDYVEEPKNNTNTGVQPENTSPPGDLNPRTDGTLKPTAFLDPEEQPSTPAPKVEQQEEILRPDTTDQGTPEFPEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDETAVRPGYPKLIQDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPGYPRNISEGFSGIPDNVDAAFALPAHRYSGRERVYFFKGKQYWEYEFQQQPSQEECEGSSLSAVFEHFALLQRDSWENIFELLF... | cell adhesion mediated by integrin cell migration cell-matrix adhesion endodermal cell differentiation extracellular matrix organization immune response liver regeneration negative regulation of fibrinolysis oligodendrocyte differentiation positive regulation of cell-substrate adhesion positive regulation of peptidyl-t... |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway glucose homeostasis negative regulation of apoptotic process positive regulation of insulin secretion involved in cellular response to glucose stimulus protein kinase A signaling regulation of insulin secretion response to activity | extracellular space | glucagon receptor binding hormone activity | Canis lupus familiaris | Amidation Cleavage on pair of basic residues Direct protein sequencing Hormone Phosphoprotein Reference proteome Secreted Signal | MKSIYFVAGL | MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSAPQTEPLNDLDQMNEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNKNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRGRRDFPEEVAIVEEFRRRHADGSFSDEMNTVLDTLATRDFINWLLQTKITDRK | adenylate cyclase-modulating G protein-coupled receptor signaling pathway glucose homeostasis negative regulation of apoptotic process positive regulation of insulin secretion involved in cellular response to glucose stimulus protein kinase A signaling regulation of insulin secretion response to activity extracellular ... |
adenylate cyclase-activating adrenergic receptor signaling pathway adenylate cyclase-activating dopamine receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of cAMP-mediated signaling positive regulation of GTPase activity sensory perception of chemic... | heterotrimeric G-protein complex | adenylate cyclase activator activity beta-2 adrenergic receptor binding corticotropin-releasing hormone receptor 1 binding D1 dopamine receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity insulin-like growth factor receptor binding ionotropic glutamate receptor binding metal ion bin... | Sus scrofa | Cell membrane GTP-binding Lipoprotein Magnesium Membrane Metal-binding Nucleotide-binding Palmitate Reference proteome Transducer | MGCLGNSKTE | MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIELFVLDDRLFQERPFSFIEDYFPEFAR... | adenylate cyclase-activating adrenergic receptor signaling pathway adenylate cyclase-activating dopamine receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of cAMP-mediated signaling positive regulation of GTPase activity sensory perception of chemic... |
proteolysis | host cell cytoplasm; T=13 icosahedral viral capsid | metal ion binding serine-type peptidase activity structural molecule activity | Avian infectious bursal disease virus | Capsid protein Host cytoplasm Hydrolase Metal-binding Protease Serine protease T=13 icosahedral capsid protein Virion | MTNLQDQTQQ | MTNLQDQTQQIVPFIRSLLMPTTGPASIPDDTLEKHTLRSETSTYNLTVGDTGSGLIVFFPGFPGSIVGAHYTLQSNGNYKFDQMLLTAQNLPASYNYCRLVSRSLTVRSSTLPGGVYALNGTINAVTFQGSLSELTDVSYNGLMSATANINDKIGNVLVGEGVTVLSLPTSYDLGYVRLGDPIPAIGLDPKMVATCDSSDRPRVYTITAADNYQFSSQYQTGGVTITLFSANIDAITSLSVGGELVFKTSVQSLVLGATICLIGFDGTAVITRAVAANNGLTAGIDNLMPFNLVIPTNEITQPITSIKLEIVTSKSDGQ... | proteolysis host cell cytoplasm; T=13 icosahedral viral capsid metal ion binding serine-type peptidase activity structural molecule activity Avian infectious bursal disease virus Capsid protein Host cytoplasm Hydrolase Metal-binding Protease Serine protease T=13 icosahedral capsid protein Virion MTNLQDQTQQ MTNLQDQTQQ... |
acetyl-CoA biosynthetic process from pyruvate glucose metabolic process pyruvate metabolic process tricarboxylic acid cycle | mitochondrial matrix; mitochondrial pyruvate dehydrogenase complex; mitochondrion; nucleolus; nucleus | pyruvate dehydrogenase (acetyl-transferring) activity pyruvate dehydrogenase (NAD+) activity | Homo sapiens | Carbohydrate metabolism Glucose metabolism Mitochondrion Oxidoreductase Phosphoprotein Pyruvate Reference proteome Thiamine pyrophosphate Transit peptide Tricarboxylic acid cycle | MLAAFISRVL | MLAAFISRVLRRVAQKSARRVLVASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGTSTERAAASPDYYKRGNFIPGLKVDGMDVLCVREATKFAANYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKRDPIIILQD... | acetyl-CoA biosynthetic process from pyruvate glucose metabolic process pyruvate metabolic process tricarboxylic acid cycle mitochondrial matrix; mitochondrial pyruvate dehydrogenase complex; mitochondrion; nucleolus; nucleus pyruvate dehydrogenase (acetyl-transferring) activity pyruvate dehydrogenase (NAD+) activity H... |
cell development developmental pigmentation melanin biosynthetic process melanin biosynthetic process from tyrosine neuroblast proliferation pigmentation positive regulation of neuroblast proliferation response to blue light ventricular zone neuroblast division | cytoplasm; cytosol; intracellular membrane-bounded organelle; melanosome; melanosome membrane; plasma membrane | dopachrome isomerase activity metal ion binding oxidoreductase activity | Mus musculus | Disease variant Glycoprotein Isomerase Melanin biosynthesis Membrane Metal-binding Reference proteome Signal Transmembrane Transmembrane helix Zinc | MGLVGWGLLL | MGLVGWGLLLGCLGCGILLRARAQFPRVCMTLDGVLNKECCPPLGPEATNICGFLEGRGQCAEVQTDTRPWSGPYILRNQDDREQWPRKFFNRTCKCTGNFAGYNCGGCKFGWTGPDCNRKKPAILRRNIHSLTAQEREQFLGALDLAKKSIHPDYVITTQHWLGLLGPNGTQPQIANCSVYDFFVWLHYYSVRDTLLGPGRPYKAIDFSHQGPAFVTWHRYHLLWLERELQRLTGNESFALPYWNFATGKNECDVCTDELLGAARQDDPTLISRNSRFSTWEIVCDSLDDYNRRVTLCNGTYEGLLRRNKVGRNNEKLP... | cell development developmental pigmentation melanin biosynthetic process melanin biosynthetic process from tyrosine neuroblast proliferation pigmentation positive regulation of neuroblast proliferation response to blue light ventricular zone neuroblast division cytoplasm; cytosol; intracellular membrane-bounded organel... |
antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen B cell affinity maturation cellular response to dexamethasone stimulus cellular response to glucocorticoid stimulus cellular response to morphine c... | cell surface; early endosome; external side of plasma membrane; Golgi apparatus; late endosome membrane; lysosomal membrane; membrane; MHC class II protein complex; multivesicular body; plasma membrane | MHC class II protein complex binding peptide antigen binding protein antigen binding protein-containing complex binding toxic substance binding ubiquitin protein ligase binding | Rattus norvegicus | 3D-structure Adaptive immunity Disulfide bond Glycoprotein Immunity Isopeptide bond Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | MALQTPSFLL | MALQTPSFLLPAAVVVLMVLSSPGTEGRDSPRDFVYQFKGLCYYTNGTQRIRDVIRYIYNQEEYLRYDSDVGEYRALTELGRPSAEYFNKQYLEQTRAELDTVCRHNYEGSEVRTSLRRLEQPNVAISLSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTQLIRNGDWTFQILVMLEMTPQRGEVYICHVDHPSLESPVTVEWRAQSESAQSKMLSGIGGFVLGVIFLGLGLFIRHKRQKGPRGPPPAGLLQ | antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen B cell affinity maturation cellular response to dexamethasone stimulus cellular response to glucocorticoid stimulus cellular response to morphine c... |
deactivation of rhodopsin mediated signaling G protein-coupled receptor signaling pathway negative regulation of smoothened signaling pathway phototransduction rhodopsin mediated signaling pathway visual perception | axon; cytoplasm; heterotrimeric G-protein complex; rhabdomere | phospholipase activator activity protein heterodimerization activity signaling receptor complex adaptor activity | Drosophila melanogaster | Cell projection Cytoplasm Reference proteome Repeat Sensory transduction Transducer Vision WD repeat | MPKIDPETQK | MPKIDPETQKLYDEINGMIQKFKDDQKSKADCTLADKCGDMGDVPKIRFSSKKILKGHINKVNSVHFAGDSRHCVTGSLDGKLIIWDTWTANKVQIIPLRSAWVMTVAFSPSGNFVACGGMDNQCTVYDVNNRDASGVAKMVKELMGYEGFLSSCRFLDDGHLITGSGDMKICHWDLEKGVKTMDFNGHAGDIAGLSLSPDMKTYITGSVDKTAKLWDVREEGHKQMFFGHDMDVSSVCYHPSGFGFASCSEDQTARMYDLRADQQIAQYEPPQKNTGFTSCALSTSGRYLMCGGIEGNVHSWDTMKQRHTGTLSGHENR... | deactivation of rhodopsin mediated signaling G protein-coupled receptor signaling pathway negative regulation of smoothened signaling pathway phototransduction rhodopsin mediated signaling pathway visual perception axon; cytoplasm; heterotrimeric G-protein complex; rhabdomere phospholipase activator activity protein he... |
chaperone cofactor-dependent protein refolding endoplasmic reticulum unfolded protein response intestinal stem cell homeostasis negative regulation of organ growth positive regulation of hippo signaling protein refolding regulatory ncRNA-mediated post-transcriptional gene silencing response to endoplasmic reticulum str... | cytoplasm; endomembrane system; endoplasmic reticulum; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen; extracellular space; membrane; nucleus | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone heat shock protein binding protein folding chaperone protein-transporting ATPase activity | Drosophila melanogaster | ATP-binding Chaperone Endoplasmic reticulum Hydrolase Nucleotide-binding Phosphoprotein Reference proteome Signal | MKLCILLAVV | MKLCILLAVVAFVGLSLGEEKKEKDKELGTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSE... | chaperone cofactor-dependent protein refolding endoplasmic reticulum unfolded protein response intestinal stem cell homeostasis negative regulation of organ growth positive regulation of hippo signaling protein refolding regulatory ncRNA-mediated post-transcriptional gene silencing response to endoplasmic reticulum str... |
autophagy of mitochondrion chaperone cofactor-dependent protein refolding mitochondrion organization positive regulation of mitochondrial membrane potential protein import into mitochondrial matrix protein refolding | cytoplasm; mitochondrial inner membrane; mitochondrion; PAM complex, Tim23 associated import motor | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone enzyme regulator activity heat shock protein binding mitochondrial protein-transporting ATPase activity protein folding chaperone unfolded protein binding | Drosophila melanogaster | ATP-binding Nucleotide-binding Phosphoprotein Reference proteome Stress response | MLRVPKFLPR | MLRVPKFLPRLARQAGVVPSHMSGASSMFRNLPGASNGISSQLRYKSGEVKGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVSSTDGKVYSPSQIGAFILMKMKETAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTEDKIIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQRLKEAAEKAKCELS... | autophagy of mitochondrion chaperone cofactor-dependent protein refolding mitochondrion organization positive regulation of mitochondrial membrane potential protein import into mitochondrial matrix protein refolding cytoplasm; mitochondrial inner membrane; mitochondrion; PAM complex, Tim23 associated import motor ATP b... |
carbohydrate metabolic process cell wall mannoprotein biosynthetic process GDP-mannose biosynthetic process protein glycosylation | cytoplasm; cytosol; nucleus | mannose-6-phosphate isomerase activity zinc ion binding | Saccharomyces cerevisiae | Acetylation Cytoplasm Direct protein sequencing Isomerase Metal-binding Phosphoprotein Reference proteome Zinc | MSNKLFRLDA | MSNKLFRLDAGYQQYDWGKIGSSSAVAQFAAHSDPSVQIEQDKPYAELWMGTHSKMPSYNHESKESLRDIISKNPSAMLGKDIIDKFHATNELPFLFKVLSIEKVLSIQAHPDKALGKILHAQDPKNYPDDNHKPEMAIAVTDFEGFCGFKPLQEIADELKRIPELRNIVGEETSRNFIENIQPSAQKGSPEDEQNKKLLQAVFSRVMNASDDKIKIQARSLVERSKNSPSDFNKPDLPELIQRLNKQFPDDVGLFCGCLLLNHCRLNAGEAIFLRAKDPHAYISGDIMECMAASDNVVRAGFTPKFKDVKNLVSMLTYT... | carbohydrate metabolic process cell wall mannoprotein biosynthetic process GDP-mannose biosynthetic process protein glycosylation cytoplasm; cytosol; nucleus mannose-6-phosphate isomerase activity zinc ion binding Saccharomyces cerevisiae Acetylation Cytoplasm Direct protein sequencing Isomerase Metal-binding Phosphop... |
carbohydrate metabolic process | extracellular region | alpha-amylase activity metal ion binding | Pseudoalteromonas haloplanktis | 3D-structure Calcium Carbohydrate metabolism Chloride Direct protein sequencing Disulfide bond Glycosidase Hydrolase Metal-binding Secreted Signal | MKLNKIITTA | MKLNKIITTAGLSLGLLLPSIATATPTTFVHLFEWNWQDVAQECEQYLGPKGYAAVQVSPPNEHITGSQWWTRYQPVSYELQSRGGNRAQFIDMVNRCSAAGVDIYVDTLINHMAAGSGTGTAGNSFGNKSFPIYSPQDFHESCTINNSDYGNDRYRVQNCELVGLADLDTASNYVQNTIAAYINDLQAIGVKGFRFDASKHVAASDIQSLMAKVNGSPVVFQEVIDQGGEAVGASEYLSTGLVTEFKYSTELGNTFRNGSLAWLSNFGEGWGFMPSSSAVVFVDNHDNQRGHGGAGNVITFEDGRLYDLANVFMLAYPY... | carbohydrate metabolic process extracellular region alpha-amylase activity metal ion binding Pseudoalteromonas haloplanktis 3D-structure Calcium Carbohydrate metabolism Chloride Direct protein sequencing Disulfide bond Glycosidase Hydrolase Metal-binding Secreted Signal MKLNKIITTA MKLNKIITTAGLSLGLLLPSIATATPTTFVHLFEWNWQ... |
B cell differentiation B cell proliferation CD40 signaling pathway inflammatory response integrin-mediated signaling pathway isotype switching leukocyte cell-cell adhesion negative regulation of apoptotic process platelet activation positive regulation of endothelial cell apoptotic process positive regulation of interl... | cell surface; external side of plasma membrane; extracellular space; Golgi apparatus; membrane; plasma membrane | CD40 receptor binding cytokine activity integrin binding protein serine/threonine kinase activator activity tumor necrosis factor receptor binding | Homo sapiens | 3D-structure Cell membrane Cytokine Direct protein sequencing Disease variant Disulfide bond Glycoprotein Membrane Reference proteome Secreted Signal-anchor Transmembrane Transmembrane helix | MIETYNQTSP | MIETYNQTSPRSAATGLPISMKIFMYLLTVFLITQMIGSALFAVYLHRRLDKIEDERNLHEDFVFMKTIQRCNTGERSLSLLNCEEIKSQFEGFVKDIMLNKEETKKENSFEMQKGDQNPQIAAHVISEASSKTTSVLQWAEKGYYTMSNNLVTLENGKQLTVKRQGLYYIYAQVTFCSNREASSQAPFIASLCLKSPGRFERILLRAANTHSSAKPCGQQSIHLGGVFELQPGASVFVNVTDPSQVSHGTGFTSFGLLKL | B cell differentiation B cell proliferation CD40 signaling pathway inflammatory response integrin-mediated signaling pathway isotype switching leukocyte cell-cell adhesion negative regulation of apoptotic process platelet activation positive regulation of endothelial cell apoptotic process positive regulation of interl... |
actin crosslink formation actin filament bundle assembly actin filament organization apoptotic process central nervous system development mitochondrion organization neural tube development neurogenesis response to endoplasmic reticulum stress | actin cytoskeleton; actin filament bundle; cell cortex; centrosome; cytoplasm; extracellular exosome; focal adhesion; germinal vesicle; plasma membrane | actin filament binding calmodulin binding identical protein binding protein kinase C binding | Homo sapiens | Actin-binding Calmodulin-binding Cytoplasm Cytoskeleton Lipoprotein Membrane Myristate Phosphoprotein Reference proteome | MGAQFSKTAA | MGAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPE... | actin crosslink formation actin filament bundle assembly actin filament organization apoptotic process central nervous system development mitochondrion organization neural tube development neurogenesis response to endoplasmic reticulum stress actin cytoskeleton; actin filament bundle; cell cortex; centrosome; cytoplasm... |
monoatomic cation transmembrane transport response to stimulus visual perception | intracellular cyclic nucleotide activated cation channel complex; photoreceptor outer segment membrane; plasma membrane | cGMP binding intracellular cAMP-activated cation channel activity intracellular cGMP-activated cation channel activity protein-containing complex binding | Homo sapiens | 3D-structure Cell membrane cGMP cGMP-binding Coiled coil Disease variant Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Nucleotide-binding Reference proteome Retinitis pigmentosa Sensory transduction Transmembrane Transmembrane helix Transport Vision | MKNNIINTQQ | MKNNIINTQQSFVTMPNVIVPDIEKEIRRMENGACSSFSEDDDSASTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKEVVVIDPSGNTYYNWLFCITLPVMYNWTMVIARACFDELQSDYLEYWLILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKA... | monoatomic cation transmembrane transport response to stimulus visual perception intracellular cyclic nucleotide activated cation channel complex; photoreceptor outer segment membrane; plasma membrane cGMP binding intracellular cAMP-activated cation channel activity intracellular cGMP-activated cation channel activity ... |
membrane depolarization monoatomic cation transmembrane transport regulation of cytosolic calcium ion concentration response to stimulus visual perception | intracellular cyclic nucleotide activated cation channel complex; membrane; photoreceptor outer segment; photoreceptor outer segment membrane; plasma membrane; terminal bouton | cGMP binding intracellular cAMP-activated cation channel activity intracellular cGMP-activated cation channel activity protein-containing complex binding | Mus musculus | Cell membrane cGMP cGMP-binding Coiled coil Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Nucleotide-binding Reference proteome Sensory transduction Transmembrane Transmembrane helix Transport Vision | MKTNIINTWH | MKTNIINTWHSFVNIPNVIVPAIEKEIRRMENGACSSFSDDDNGSLSEESENEDSFFRSNSYKRRGPSQREQHLPGTMALFNVNNSSNKDQEPKEKKKKKKEKKSKADDKNENKKDPEKKKKKEKEKEKKKKEEKTKEKKEEEKKEVVVIDPSGNTYYNWLFCITLPVMYNWTMIIARACFDELQSDYLEYWLIFDYVSDVVYLADMFVRTRTGYLEQGLLVKDRMKLIEKYKANLQFKLDVLSVIPTDLLYIKFGWNYPEIRLNRLLRISRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVYYSISKAIGFG... | membrane depolarization monoatomic cation transmembrane transport regulation of cytosolic calcium ion concentration response to stimulus visual perception intracellular cyclic nucleotide activated cation channel complex; membrane; photoreceptor outer segment; photoreceptor outer segment membrane; plasma membrane; termi... |
action potential adenylate cyclase-modulating G protein-coupled receptor signaling pathway cellular response to pH cranial skeletal system development developmental pigmentation endothelin receptor signaling pathway entrainment of circadian clock G protein-coupled acetylcholine receptor signaling pathway heart developm... | cytoplasm; extracellular exosome; heterotrimeric G-protein complex; lysosomal membrane; photoreceptor outer segment; plasma membrane; synapse | enzyme regulator activity G protein activity G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding | Homo sapiens | 3D-structure ADP-ribosylation Cell membrane Cytoplasm Direct protein sequencing Disease variant GTP-binding Host-virus interaction Lipoprotein Magnesium Membrane Metal-binding Nucleotide-binding Palmitate Reference proteome Transducer | MTLESMMACC | MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVEKVTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDS... | action potential adenylate cyclase-modulating G protein-coupled receptor signaling pathway cellular response to pH cranial skeletal system development developmental pigmentation endothelin receptor signaling pathway entrainment of circadian clock G protein-coupled acetylcholine receptor signaling pathway heart developm... |
exit of virus from host cell nucleus through nuclear pore viral entry into host cell viral penetration into host nucleus | host cell nucleolus; virion component | RNA binding | Hepatitis delta virus genotype I | Acetylation Host nucleus Lipoprotein Methylation Phosphoprotein Prenylation Reference proteome RNA editing RNA-binding Viral penetration into host nucleus Virion Virus entry into host cell | MSRPEGRKNR | MSRPEGRKNRGGREEVLEQWVSGRKKLEELERDLRKVKKKIKKLEDEHPWLGNIKGILGKKDKDGEGAPPAKRARTDQMEVDSGPRKRPSRGGFTDKERQDHRRRKALENKRKQLSAGGKNLSKEEEEELRRLTEEDERRERRIAGPQVGGVNPLEGGTRGAPGGGFVPSMQGVPESPFTRTGEGLDIRGSQGFPWDILFPADPPSSPQSCRPQ | exit of virus from host cell nucleus through nuclear pore viral entry into host cell viral penetration into host nucleus host cell nucleolus; virion component RNA binding Hepatitis delta virus genotype I Acetylation Host nucleus Lipoprotein Methylation Phosphoprotein Prenylation Reference proteome RNA editing RNA-bind... |
actin crosslink formation actin filament bundle assembly actin filament organization apoptotic process cell-substrate adhesion central nervous system development intracellular protein transport mitochondrion organization neural tube development neurogenesis positive regulation of dendritic spine morphogenesis positive ... | actin filament bundle; axon terminus; bleb; cell cortex; centrosome; chromatoid body; cytoplasm; dendritic branch; dendritic spine; germinal vesicle; glutamatergic synapse; growth cone; membrane; organelle; outer dense fiber; plasma membrane; postsynaptic cytoskeleton; postsynaptic membrane; presynaptic cytosol; presyn... | actin filament binding calmodulin binding identical protein binding phosphatidylserine binding phospholipid binding protein kinase C binding | Rattus norvegicus | Actin-binding Calmodulin-binding Cytoplasm Cytoskeleton Direct protein sequencing Lipoprotein Membrane Myristate Phosphoprotein Reference proteome | MGAQFSKTAA | MGAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAEPGAKEELQANGSAPAADKEEPASGGAATPAAADKDEAAAAPEPGAATADKEAAEAEPAEPGSPSAETEGASASSTSSPKAEDGAAPSPSSETPKKKKKRFSFKKSFKLSGFSFKKSKKEAGEGAEAEGATADGAKDEAAAAAGGDAAAAPGEQAGGAGAEGAEGGESREAEAAEPEQPEQPEQPAAEEPRAEEPSEAVGEKAEEPAPGATADDAPSAAGPEQEAPAATDEPAASAAPSASPEPQPECSPEAPPAPVAE | actin crosslink formation actin filament bundle assembly actin filament organization apoptotic process cell-substrate adhesion central nervous system development intracellular protein transport mitochondrion organization neural tube development neurogenesis positive regulation of dendritic spine morphogenesis positive ... |
de novo' NAD biosynthetic process from aspartate NAD biosynthetic process quinolinate catabolic process | cytoplasm; cytosol | nicotinate-nucleotide diphosphorylase (carboxylating) activity | Escherichia coli | Glycosyltransferase Pyridine nucleotide biosynthesis Reference proteome Transferase | MPPRRYNPDT | MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANNDITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINANQSLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLRSALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVENLEELDEALKAGADIIMLDNFETEQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVDFISVGALTKHVQALDLSMRFR | de novo' NAD biosynthetic process from aspartate NAD biosynthetic process quinolinate catabolic process cytoplasm; cytosol nicotinate-nucleotide diphosphorylase (carboxylating) activity Escherichia coli Glycosyltransferase Pyridine nucleotide biosynthesis Reference proteome Transferase MPPRRYNPDT MPPRRYNPDTRRDELLERINLD... |
DNA damage response DNA replication proofreading regulatory ncRNA 3'-end processing rRNA 3'-end processing tRNA 3'-end processing | cytosol | 3'-5' exonuclease activity 3'-5'-RNA exonuclease activity identical protein binding magnesium ion binding nucleic acid binding protein homodimerization activity single-stranded DNA 3'-5' DNA exonuclease activity | Escherichia coli | 3D-structure Exonuclease Hydrolase Magnesium Metal-binding Nuclease Reference proteome tRNA processing | MSDNAQLTGL | MSDNAQLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITLKMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKVVRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALGQTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLSAAEEV | DNA damage response DNA replication proofreading regulatory ncRNA 3'-end processing rRNA 3'-end processing tRNA 3'-end processing cytosol 3'-5' exonuclease activity 3'-5'-RNA exonuclease activity identical protein binding magnesium ion binding nucleic acid binding protein homodimerization activity single-stranded DNA 3... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide chemokine-mediated signaling pathway cytokine-mediated signaling pathway inflammatory response leukocyte chemotaxis negative regulatio... | extracellular space | chemokine activity CXCR chemokine receptor binding CXCR3 chemokine receptor binding heparin binding | Sus scrofa | Chemotaxis Cytokine Direct protein sequencing Disulfide bond Glycoprotein Heparin-binding Phosphoprotein Pyrrolidone carboxylic acid Reference proteome Secreted | QEWSLPGTRV | QEWSLPGTRVPPPADPEGGDANLRCVCVKTISGVSPKHISSLEVIGAGPHCPSPQLIATLKKGHKICLDPQNLLYKKIIKKLLKSQLLTA | adenylate cyclase-activating G protein-coupled receptor signaling pathway antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide chemokine-mediated signaling pathway cytokine-mediated signaling pathway inflammatory response leukocyte chemotaxis negative regulatio... |
4-hydroxyproline catabolic process proline catabolic process proline catabolic process to glutamate proline metabolic process | cytosol; mitochondrial matrix; mitochondrion | 1-pyrroline-5-carboxylate dehydrogenase activity aldehyde dehydrogenase (NAD+) activity electron transfer activity identical protein binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Direct protein sequencing Disease variant Mitochondrion NAD Oxidoreductase Phosphoprotein Proline metabolism Reference proteome Transit peptide | MLLPAPALRR | MLLPAPALRRALLSRPWTGAGLRWKHTSSLKVANEPVLAFTQGSPERDALQKALKDLKGRMEAIPCVVGDEEVWTSDVQYQVSPFNHGHKVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNF... | 4-hydroxyproline catabolic process proline catabolic process proline catabolic process to glutamate proline metabolic process cytosol; mitochondrial matrix; mitochondrion 1-pyrroline-5-carboxylate dehydrogenase activity aldehyde dehydrogenase (NAD+) activity electron transfer activity identical protein binding Homo sap... |
biosynthetic process maintenance of gastrointestinal epithelium negative regulation of transforming growth factor beta receptor signaling pathway | cytoplasm; extracellular exosome | identical protein binding isomerase activity | Homo sapiens | Alternative splicing Direct protein sequencing Isomerase Reference proteome | MKLPIFIADA | MKLPIFIADAFTARAFRGNPAAVCLLENELDEDMHQKIAREMNLSETAFIRKLHPTDNFAQSSCFGLRWFTPASEVPLCGHATLASAAVLFHKIKNMNSTLTFVTLSGELRARRAEDGIVLDLPLYPAHPQDFHEVEDLIKTAIGNTLVQDICYSPDTQKLLVRLSDVYNRSFLENLKVNTENLLQVENTGKVKGLILTLKGEPGGQTQAFDFYSRYFAPWVGVAEDPVTGSAHAVLSSYWSQHLGKKEMHAFQCSHRGGELGISLRPDGRVDIRGGAAVVLEGTLTA | biosynthetic process maintenance of gastrointestinal epithelium negative regulation of transforming growth factor beta receptor signaling pathway cytoplasm; extracellular exosome identical protein binding isomerase activity Homo sapiens Alternative splicing Direct protein sequencing Isomerase Reference proteome MKLPIFI... |
intracellular protein transport negative regulation of gene expression negative regulation of protein secretion positive regulation of gene expression positive regulation of MAP kinase activity positive regulation of protein phosphorylation protein folding protein secretion protein unfolding regulation of endoplasmic r... | cell surface; endoplasmic reticulum; endoplasmic reticulum lumen; melanosome; membrane; smooth endoplasmic reticulum; transport vesicle | protein homodimerization activity protein-folding chaperone binding | Homo sapiens | 3D-structure Alternative splicing Direct protein sequencing Endoplasmic reticulum Phosphoprotein Reference proteome Signal | MAAAVPRAAF | MAAAVPRAAFLSPLLPLLLGFLLLSAPHGGSGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFRDGDFENPVPYTGAVKVGAIQRWLKGQGVYLGMPGCLPVYDALAGEFIRASGVEARQALLKQGQDNLSSVKETQKKWAEQYLKIMGKILDQGEDFPASEMTRIARLIEKNKMSDGKKEELQKSLNILTAFQKKGAEKEEL | intracellular protein transport negative regulation of gene expression negative regulation of protein secretion positive regulation of gene expression positive regulation of MAP kinase activity positive regulation of protein phosphorylation protein folding protein secretion protein unfolding regulation of endoplasmic r... |
cell redox homeostasis cellular oxidant detoxification glycerophospholipid catabolic process positive regulation of mRNA splicing, via spliceosome response to oxidative stress | azurophil granule lumen; cytoplasm; cytosol; extracellular exosome; extracellular region; extracellular space; membrane; mitochondrion; nucleus; perinuclear region of cytoplasm | 1-acylglycerophosphocholine O-acyltransferase activity cadherin binding calcium-independent phospholipase A2 activity glutathione peroxidase activity identical protein binding peroxiredoxin activity phospholipase A2 activity ubiquitin protein ligase binding | Homo sapiens | 3D-structure Acetylation Antioxidant Cytoplasm Direct protein sequencing Hydrolase Lipid degradation Lipid metabolism Lysosome Multifunctional enzyme Oxidoreductase Peroxidase Phosphoprotein Redox-active center Reference proteome Transferase | MPGGLLLGDV | MPGGLLLGDVAPNFEANTTVGRIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIALSIDSVEDHLAWSKDINAYNCEEPTEKLPFPIIDDRNRELAILLGMLDPAEKDEKGMPVTARVVFVFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATPVDWKDGDSVMVLPTIPEEEAKKLFPKGVFTKELPSGKKYLRYTPQP | cell redox homeostasis cellular oxidant detoxification glycerophospholipid catabolic process positive regulation of mRNA splicing, via spliceosome response to oxidative stress azurophil granule lumen; cytoplasm; cytosol; extracellular exosome; extracellular region; extracellular space; membrane; mitochondrion; nucleus;... |
heme catabolic process | cytosol; extracellular exosome; intracellular membrane-bounded organelle; nucleoplasm; plasma membrane; terminal bouton | biliberdin reductase NAD+ activity biliverdin reductase (NAD(P)+) activity biliverdin reductase (NADP+) activity riboflavin reductase (NADPH) activity | Homo sapiens | 3D-structure Cytoplasm Direct protein sequencing NADP Oxidoreductase Phosphoprotein Reference proteome | MAVKKIAIFG | MAVKKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAADVDKTVAGQDAVIVLLGTRNDLSPTTVMSEGARNIVAAMKAHGVDKVVACTSAFLLWDPTKVPPRLQAVTDDHIRMHKVLRESGLKYVAVMPPHIGDQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTDEYDGHSTYPSHQYQ | heme catabolic process cytosol; extracellular exosome; intracellular membrane-bounded organelle; nucleoplasm; plasma membrane; terminal bouton biliberdin reductase NAD+ activity biliverdin reductase (NAD(P)+) activity biliverdin reductase (NADP+) activity riboflavin reductase (NADPH) activity Homo sapiens 3D-structure ... |
cell redox homeostasis cellular response to oxidative stress cellular response to reactive oxygen species hydrogen peroxide catabolic process inflammatory response NADPH oxidation negative regulation of apoptotic process negative regulation of oxidoreductase activity negative regulation of transcription by RNA polymera... | cytoplasm; cytoplasmic vesicle; cytosol; extracellular exosome; extracellular space; intracellular membrane-bounded organelle; mitochondrial matrix; mitochondrion; nucleus; perinuclear region of cytoplasm; peroxisomal matrix; peroxisome | antioxidant activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process identical protein binding peroxidase activity peroxynitrite reductase activity RNA polymerase III transcription regulatory region sequence-specific DNA binding signaling receptor binding thioredoxin peroxidase activity | Homo sapiens | 3D-structure Acetylation Alternative initiation Alternative splicing Antioxidant Cytoplasm Direct protein sequencing Disulfide bond Lipoprotein Mitochondrion Oxidoreductase Palmitate Peroxidase Peroxisome Phosphoprotein Redox-active center Reference proteome Transit peptide | MGLAGVCALR | MGLAGVCALRRSAGYILVGGAGGQSAAAAARRYSEGEWASGGVRSFSRAAAAMAPIKVGDAIPAVEVFEGEPGNKVNLAELFKGKKGVLFGVPGAFTPGCSKTHLPGFVEQAEALKAKGVQVVACLSVNDAFVTGEWGRAHKAEGKVRLLADPTGAFGKETDLLLDDSLVSIFGNRRLKRFSMVVQDGIVKALNVEPDGTGLTCSLAPNIISQL | cell redox homeostasis cellular response to oxidative stress cellular response to reactive oxygen species hydrogen peroxide catabolic process inflammatory response NADPH oxidation negative regulation of apoptotic process negative regulation of oxidoreductase activity negative regulation of transcription by RNA polymera... |
melanin biosynthetic process negative regulation of macrophage chemotaxis positive regulation of ERK1 and ERK2 cascade positive regulation of inflammatory response positive regulation of tumor necrosis factor production | cytoplasm; extracellular exosome; extracellular space | cytokine receptor binding D-dopachrome decarboxylase activity dopachrome isomerase activity phenylpyruvate tautomerase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Lyase Melanin biosynthesis Reference proteome | MPFLELDTNL | MPFLELDTNLPANRVPAGLEKRLCAAAASILGKPADRVNVTVRPGLAMALSGSTEPCAQLSISSIGVVGTAEDNRSHSAHFFEFLTKELALGQDRILIRFFPLESWQIGKIGTVMTFL | melanin biosynthetic process negative regulation of macrophage chemotaxis positive regulation of ERK1 and ERK2 cascade positive regulation of inflammatory response positive regulation of tumor necrosis factor production cytoplasm; extracellular exosome; extracellular space cytokine receptor binding D-dopachrome decarbo... |
negative regulation of biosynthetic process regulation of nitric oxide biosynthetic process | cytoplasm; cytosol; dendrite; melanosome; nuclear membrane; nucleoplasm; nucleus | GTP cyclohydrolase binding | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Membrane Nucleus Reference proteome | MPYLLISTQI | MPYLLISTQIRMEVGPTMVGDEQSDPELMQHLGASKRRALGNNFYEYYVDDPPRIVLDKLERRGFRVLSMTGVGQTLVWCLHKE | negative regulation of biosynthetic process regulation of nitric oxide biosynthetic process cytoplasm; cytosol; dendrite; melanosome; nuclear membrane; nucleoplasm; nucleus GTP cyclohydrolase binding Homo sapiens 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Membrane Nucleus Reference proteome M... |
cell redox homeostasis cellular response to oxidative stress cellular response to reactive oxygen species hydrogen peroxide catabolic process maternal placenta development mitochondrion organization myeloid cell differentiation negative regulation of apoptotic process negative regulation of kinase activity peptidyl-cys... | cytoplasm; cytosol; early endosome; intracellular membrane-bounded organelle; mitochondrial matrix; mitochondrion; nucleoplasm; plasma membrane; protein-containing complex | alkyl hydroperoxide reductase activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process identical protein binding protein kinase binding thioredoxin peroxidase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Antioxidant Corneal dystrophy Cytoplasm Direct protein sequencing Disease variant Disulfide bond Endosome Lipoprotein Mitochondrion Neurodegeneration Oxidoreductase Palmitate Peroxidase Phosphoprotein Redox-active center Reference proteome Transit peptide | MAAAVGRLLR | MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ | cell redox homeostasis cellular response to oxidative stress cellular response to reactive oxygen species hydrogen peroxide catabolic process maternal placenta development mitochondrion organization myeloid cell differentiation negative regulation of apoptotic process negative regulation of kinase activity peptidyl-cys... |
aerobic respiration mitochondrial proton-transporting ATP synthase complex assembly proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis response to copper ion | mitochondrial inner membrane; mitochondrial matrix; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1); mitochondrion | proton-transporting ATP synthase activity, rotational mechanism | Homo sapiens | 3D-structure Acetylation ATP synthesis CF(1) Direct protein sequencing Disease variant Hydrogen ion transport Ion transport Membrane Mitochondrion Mitochondrion inner membrane Primary mitochondrial disease Reference proteome Transit peptide Transport | MLPAALLRRP | MLPAALLRRPGLGRLVRHARAYAEAAAAPAAASGPNQMSFTFASPTQVFFNGANVRQVDVPTLTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSIAVNADSSVQLLAEEAVTLDMLDLGAAKANLEKAQAELVGTADEATRAEIQIRIEANEALVKALE | aerobic respiration mitochondrial proton-transporting ATP synthase complex assembly proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis response to copper ion mitochondrial inner membrane; mitochondrial matrix; mitochondrial proton-transporting ATP synthase complex; mitochond... |
cytoplasmic translation translation | cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; extracellular exosome; focal adhesion; membrane; nucleolus; postsynaptic density | large ribosomal subunit rRNA binding RNA binding structural constituent of ribosome | Homo sapiens | 3D-structure Acetylation Alternative splicing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding Ubl conjugation | MPPKFDPNEI | MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS | cytoplasmic translation translation cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; extracellular exosome; focal adhesion; membrane; nucleolus; postsynaptic density large ribosomal subunit rRNA binding RNA binding structural constituent of ribosome Homo sapiens 3D-structure Acetylation Altern... |
cellular response to retinoic acid embryonic heart tube morphogenesis embryonic organ development heart development hippo signaling lateral mesoderm development notochord development paraxial mesoderm development positive regulation of cell growth positive regulation of DNA-templated transcription positive regulation o... | nucleoplasm; nucleus; TEAD-YAP complex; transcription regulator complex | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Acetylation Activator DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MEPSSWSGSE | MEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGGPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVSSQYESSENMTV... | cellular response to retinoic acid embryonic heart tube morphogenesis embryonic organ development heart development hippo signaling lateral mesoderm development notochord development paraxial mesoderm development positive regulation of cell growth positive regulation of DNA-templated transcription positive regulation o... |
cardiac muscle cell development cell cycle compound eye morphogenesis embryonic organ development hippo signaling imaginal disc-derived leg morphogenesis imaginal disc-derived wing morphogenesis negative regulation of DNA-templated transcription negative regulation of neuroblast proliferation positive regulation of tra... | nucleoplasm; nucleus; RNA polymerase II transcription regulator complex; transcription regulator complex | DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding protein domain specific binding RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription cis-regulatory region binding transcription coactivator binding transcription corepressor binding | Drosophila melanogaster | 3D-structure Activator Cell cycle Developmental protein Differentiation DNA-binding Metal-binding Nucleus Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MKNITSSSTC | MKNITSSSTCSTGLLQLQNNLSCSELEVAEKTEQQAVGPGTIPSPWTPVNAGPPGALGSADTNGSMVDSKNLDVGDMSDDEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIKVQFWQPGLQPSTSQDFYDYSIKPFPQPPYPAGKTSTAVSGDETGIPPSQLPWEGRAIATHKFRLLEFTAFMEIQRDEIYHRHLFVQLGGKPSFSDPLLETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDLTTGSETGDFY... | cardiac muscle cell development cell cycle compound eye morphogenesis embryonic organ development hippo signaling imaginal disc-derived leg morphogenesis imaginal disc-derived wing morphogenesis negative regulation of DNA-templated transcription negative regulation of neuroblast proliferation positive regulation of tra... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell surface receptor signaling pathway cellular response to glucagon stimulus cellular response to starvation exocytosis G protein-coupled receptor signaling pathway gluco... | endosome; plasma membrane | glucagon receptor activity peptide hormone binding | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix | MLLTQLHCPY | MLLTQLHCPYLLLLLVVLSCLPKAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQSWRDASQCQMDDDEIEVQKGVAKMYSSYQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGNLFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAVAGCRVATVIMQYGIIANYCWLLVEGVYLYSLLSITTFSEKSFFSLYLCIGWGSPLLFVIPWVVVKCLFENVQCWTSNDNMGFWWILRIPVLLAILINF... | adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell surface receptor signaling pathway cellular response to glucagon stimulus cellular response to starvation exocytosis G protein-coupled receptor signaling pathway gluco... |
branched-chain amino acid catabolic process fatty acid beta-oxidation | mitochondrial matrix; mitochondrion | 3-hydroxypropionyl-CoA dehydratase activity crotonyl-CoA hydratase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Disease variant Fatty acid metabolism Isomerase Lipid metabolism Lyase Mitochondrion Neurodegeneration Phosphoprotein Reference proteome Transit peptide | MAALRVLLSC | MAALRVLLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ | branched-chain amino acid catabolic process fatty acid beta-oxidation mitochondrial matrix; mitochondrion 3-hydroxypropionyl-CoA dehydratase activity crotonyl-CoA hydratase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity Homo sapiens 3D-structure Acetylation Direct protein sequencin... |
de novo' pyrimidine nucleobase biosynthetic process CDP biosynthetic process nucleobase-containing small molecule interconversion phosphorylation pyrimidine ribonucleotide biosynthetic process UDP biosynthetic process | cytoplasm; cytosol; extracellular exosome; nucleolus; nucleoplasm; nucleus | ATP binding CMP kinase activity cytidylate kinase activity dCMP kinase activity nucleoside diphosphate kinase activity nucleoside monophosphate kinase activity UMP kinase activity uridine kinase activity | Homo sapiens | 3D-structure Acetylation Alternative initiation Alternative splicing ATP-binding Cytoplasm Direct protein sequencing Isopeptide bond Kinase Nucleotide-binding Nucleus Phosphoprotein Pyrimidine biosynthesis Reference proteome Transferase Ubl conjugation | MKPLVVFVLG | MKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG | de novo' pyrimidine nucleobase biosynthetic process CDP biosynthetic process nucleobase-containing small molecule interconversion phosphorylation pyrimidine ribonucleotide biosynthetic process UDP biosynthetic process cytoplasm; cytosol; extracellular exosome; nucleolus; nucleoplasm; nucleus ATP binding CMP kinase acti... |
negative regulation of MAPK cascade | cytosol; extracellular exosome; nucleus | ATP binding enzyme binding phosphatidylethanolamine binding protein kinase binding RNA binding serine-type endopeptidase inhibitor activity | Homo sapiens | 3D-structure ATP-binding Cytoplasm Direct protein sequencing Disulfide bond Lipid-binding Nucleotide-binding Phosphoprotein Protease inhibitor Reference proteome Serine protease inhibitor | MPVDLSKWSG | MPVDLSKWSGPLSLQEVDEQPQHPLHVTYAGAAVDELGKVLTPTQVKNRPTSISWDGLDSGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTVLSDYVGSGPPKGTGLHRYVWLVYEQDRPLKCDEPILSNRSGDHRGKFKVASFRKKYELRAPVAGTCYQAEWDDYVPKLYEQLSGK | negative regulation of MAPK cascade cytosol; extracellular exosome; nucleus ATP binding enzyme binding phosphatidylethanolamine binding protein kinase binding RNA binding serine-type endopeptidase inhibitor activity Homo sapiens 3D-structure ATP-binding Cytoplasm Direct protein sequencing Disulfide bond Lipid-binding N... |
cell surface receptor signaling pathway G protein-coupled receptor signaling pathway | plasma membrane | tachykinin receptor activity transmembrane signaling receptor activity | Cavia porcellus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MASPAGNLSA | MASPAGNLSAWPGWGWPPPAALRNLTSSPAPTASPSPAPSWTPSPRPGPAHPFLQPPWAVALWSLAYGAVVAVAVLGNLVVIWIVLAHKRMRTVTNSFLVNLAFADAAMAALNALVNFIYALHGEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATRIVIGSIWILAFLLAFPQCLYSKIKVMPGRTLCYVQWPEGSRQHFTYHMIVIVLVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYQEQLKAKRKVVKMMIIVVVTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLA... | cell surface receptor signaling pathway G protein-coupled receptor signaling pathway plasma membrane tachykinin receptor activity transmembrane signaling receptor activity Cavia porcellus Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Tran... |
aldosterone biosynthetic process C21-steroid hormone biosynthetic process cellular response to hormone stimulus cellular response to mechanical stimulus cellular response to nutrient cellular response to peptide hormone stimulus cellular response to potassium ion cellular response to potassium ion starvation cholestero... | dendrite; mitochondrial inner membrane; mitochondrion | corticosterone 18-monooxygenase activity heme binding iron ion binding steroid 11-beta-monooxygenase activity | Rattus norvegicus | Direct protein sequencing Heme Iron Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Monooxygenase Oxidoreductase Reference proteome Steroidogenesis Transit peptide | MGACDNDFIE | MGACDNDFIELHSRVTADVWLARPWQCLHRTRALGTTATLAPKTLKPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQAFQELGPIFRHSAGGAQIVSVMLPEDAEKLHQVESILPRRMHLEPWVAHRELRGLRRGVFLLNGAEWRFNRLKLNPNVLSPKAVQNFVPMVDEVARDFLEALKKKVRQNARGSLTMDVQQSLFNYTIEASNFALFGERLGLLGHDLNPGSLKFIHALHSMFKSTTQLLFLPRSLTRWTSTQVWKEHFDAWDVISEYANRCIWKVHQELRLGSSQTYSGIVAALITQGALPLDAIKANSME... | aldosterone biosynthetic process C21-steroid hormone biosynthetic process cellular response to hormone stimulus cellular response to mechanical stimulus cellular response to nutrient cellular response to peptide hormone stimulus cellular response to potassium ion cellular response to potassium ion starvation cholestero... |
adrenal gland development aldosterone biosynthetic process C21-steroid hormone biosynthetic process cellular response to hormone stimulus cellular response to peptide hormone stimulus cellular response to potassium ion cholesterol metabolic process cortisol biosynthetic process cortisol metabolic process drinking behav... | mitochondrial inner membrane; mitochondrion | corticosterone 18-monooxygenase activity heme binding iron ion binding steroid 11-beta-monooxygenase activity | Rattus norvegicus | Direct protein sequencing Heme Iron Membrane Metal-binding Mitochondrion Monooxygenase Oxidoreductase Reference proteome Steroidogenesis Transit peptide | MALRVTADVW | MALRVTADVWLARPWQCLHRTRALGTTATLAPKTLKPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQAFQELGPIFRHSAGGAQIVSVMLPEDAEKLHQVESILPRRMHLEPWVAHRELRGLRRGVFLLNGAEWRFNRLKLNPNVLSPKAVQNFVPMVDEVARDFLEALKKKVRQNARGSLTMDVQQSLFNYTIEASNFALFGERLGLLGHDLNPGSLKFIHALHSMFKSTTQLLFLPRSLTRWTSTQVWKEHFDAWDVISEYANRCIWKVHQELRLGSSQTYSGIVAALITQGALPLDAIKANSMKLTAGSVDTTA... | adrenal gland development aldosterone biosynthetic process C21-steroid hormone biosynthetic process cellular response to hormone stimulus cellular response to peptide hormone stimulus cellular response to potassium ion cholesterol metabolic process cortisol biosynthetic process cortisol metabolic process drinking behav... |
adaptive immune response cellular response to interleukin-7 extrinsic apoptotic signaling pathway peptide antigen assembly with MHC class I protein complex platelet aggregation positive regulation of extrinsic apoptotic signaling pathway protein folding protein folding in endoplasmic reticulum response to endoplasmic r... | cell surface; endoplasmic reticulum; endoplasmic reticulum lumen; extracellular exosome; extracellular space; focal adhesion; melanosome; MHC class I peptide loading complex; nucleus; phagocytic vesicle; recycling endosome membrane; Tapasin-ERp57 complex | cysteine-type endopeptidase activity disulfide oxidoreductase activity identical protein binding phospholipase C activity protein disulfide isomerase activity protein-disulfide reductase activity RNA binding | Homo sapiens | 3D-structure Acetylation Adaptive immunity Direct protein sequencing Disulfide bond Endoplasmic reticulum Immunity Isomerase Methylation Phosphoprotein Redox-active center Reference proteome Repeat Signal | MRLRRLALFP | MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENIFGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTA... | adaptive immune response cellular response to interleukin-7 extrinsic apoptotic signaling pathway peptide antigen assembly with MHC class I protein complex platelet aggregation positive regulation of extrinsic apoptotic signaling pathway protein folding protein folding in endoplasmic reticulum response to endoplasmic r... |
aflatoxin catabolic process glutathione metabolic process lipid metabolic process ureteric bud development xenobiotic metabolic process | cytosol | glutathione transferase activity | Mus musculus | Acetylation Cytoplasm Direct protein sequencing Lipid metabolism Reference proteome Transferase | MAGKPVLHYF | MAGKPVLHYFDGRGRMEPIRWLLAAAGVEFEEKFLKTRDDLARLRSDGSLMFQQVPMVEIDGMKLVQTKAILNYIASKYNLYGKDMKERAIIDMYTEGVADLEIMILYYPHMPPEEKEASLAKIKEQTRNRYFPAFEKVLKSHGQDYLVGNRLSRADIALVELLYHVEELDPGVVDNFPLLKALRSRVSNLPTVKKFLQPGSQRKPFDDAKCVESAKKIFS | aflatoxin catabolic process glutathione metabolic process lipid metabolic process ureteric bud development xenobiotic metabolic process cytosol glutathione transferase activity Mus musculus Acetylation Cytoplasm Direct protein sequencing Lipid metabolism Reference proteome Transferase MAGKPVLHYF MAGKPVLHYFDGRGRMEPIRWLL... |
cartilage development cellular response to UV-A connective tissue replacement involved in inflammatory response wound healing negative regulation of apoptotic process negative regulation of catalytic activity negative regulation of endopeptidase activity negative regulation of membrane protein ectodomain proteolysis ne... | basement membrane; extracellular matrix; extracellular space | cytokine activity growth factor activity metalloendopeptidase inhibitor activity peptidase inhibitor activity protease binding zinc ion binding | Rattus norvegicus | Direct protein sequencing Disulfide bond Glycoprotein Growth factor Metal-binding Metalloenzyme inhibitor Metalloprotease inhibitor Phosphoprotein Protease inhibitor Reference proteome Secreted Signal Steroidogenesis Zinc | MAPFASLASG | MAPFASLASGILLLLSLIASSKACSCAPTHPQTAFCNSDLVIRAKFMGSPEIIETTLYQRYEIKMTKMLKGFDAVGNATGFRFAYTPAMESLCGYVHKSQNRSEEFLIAGRLRNGNLHITACSFLVPWHNLSPAQQKAFVKTYSAGCGVCTVFPCSAIPCKLESDSHCLWTDQILMGSEKGYQSDHFACLPRNPDLCTWQYLGVSMTRSLPLAKAEA | cartilage development cellular response to UV-A connective tissue replacement involved in inflammatory response wound healing negative regulation of apoptotic process negative regulation of catalytic activity negative regulation of endopeptidase activity negative regulation of membrane protein ectodomain proteolysis ne... |
cellular response to organic substance negative regulation of cell population proliferation negative regulation of membrane protein ectodomain proteolysis negative regulation of mitotic cell cycle negative regulation of proteolysis negative regulation of Ras protein signal transduction positive regulation of MAPK casca... | basement membrane; cell surface; extracellular matrix; extracellular space; growth cone; neuronal cell body | enzyme activator activity integrin binding metalloendopeptidase inhibitor activity molecular function inhibitor activity peptidase inhibitor activity protease binding zinc ion binding | Rattus norvegicus | Direct protein sequencing Disulfide bond Metal-binding Metalloenzyme inhibitor Metalloprotease inhibitor Protease inhibitor Reference proteome Secreted Signal Zinc | MGAAARSLRL | MGAAARSLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSITQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKSINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP | cellular response to organic substance negative regulation of cell population proliferation negative regulation of membrane protein ectodomain proteolysis negative regulation of mitotic cell cycle negative regulation of proteolysis negative regulation of Ras protein signal transduction positive regulation of MAPK casca... |
ceramide catabolic process pancreatic juice secretion | cytoplasm; extracellular region | acetylesterase activity retinyl-palmitate esterase activity sterol esterase activity triglyceride lipase activity | Bos taurus | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metabolism Reference proteome Secreted Serine esterase Signal | LGASRLGPSP | LGASRLGPSPGCLAVASAAKLGSVYTEGGFVEGVNKKLSLFGDSIDIFKGIPFAAAPKALEKPERHPGWQGTLKAKSFKKRCLQATLTQDSTYGNEDCLYLNIWVPQGRKEVSHDLPVMIWIYGGAFLMGASQGANFLSNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDSNLPGNYGLWDQHMAIAWVKRNIEAFGGDPDNITLFGESAGGASVSLQTLSPYNKGLIKRAISQSGVGLCPWAIQQDPLFWAKRIAEKVGCPVDDTSKMAGCLKITDPRALTLAYKLPLGSTEYPKLHYLSFVPVIDGDFIPDDPVN... | ceramide catabolic process pancreatic juice secretion cytoplasm; extracellular region acetylesterase activity retinyl-palmitate esterase activity sterol esterase activity triglyceride lipase activity Bos taurus 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metaboli... |
chlorophyll biosynthetic process protoporphyrinogen IX biosynthetic process | chloroplast | metal ion binding porphobilinogen synthase activity | Pisum sativum | Allosteric enzyme Chlorophyll biosynthesis Chloroplast Direct protein sequencing Heme biosynthesis Lyase Magnesium Metal-binding Plastid Porphyrin biosynthesis Transit peptide | HTFVDLKSPF | HTFVDLKSPFTLSNYLSFSSSKRRQPPSLFTVRASDSDFEAAVVAGKVPEAPPVPPTPASPAGTPVVPSLPIQRRPRRNRRSPALRSAFQETTLSPANFVYPLFIHEGEEDTPIGAMPGCYRLGWRHGLLEEVAKARDVGVNSVVLFPKIPDALKTPTGDEAYNEDGLVPRSIRLLKDKYPDLIIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAMRVALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTEMREDESEGADILLVKP... | chlorophyll biosynthetic process protoporphyrinogen IX biosynthetic process chloroplast metal ion binding porphobilinogen synthase activity Pisum sativum Allosteric enzyme Chlorophyll biosynthesis Chloroplast Direct protein sequencing Heme biosynthesis Lyase Magnesium Metal-binding Plastid Porphyrin biosynthesis Trans... |
cellular response to amino acid starvation leucine biosynthetic process | cytosol | 3-isopropylmalate dehydrogenase activity magnesium ion binding manganese ion binding metal ion binding NAD binding | Escherichia coli | 3D-structure Amino-acid biosynthesis Branched-chain amino acid biosynthesis Cytoplasm Direct protein sequencing Leucine biosynthesis Magnesium Manganese Metal-binding NAD Oxidoreductase Reference proteome | MSKNYHIAVL | MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAAC... | cellular response to amino acid starvation leucine biosynthetic process cytosol 3-isopropylmalate dehydrogenase activity magnesium ion binding manganese ion binding metal ion binding NAD binding Escherichia coli 3D-structure Amino-acid biosynthesis Branched-chain amino acid biosynthesis Cytoplasm Direct protein sequenc... |
protein maturation protein-containing complex assembly | ATPase complex | carboxyl- or carbamoyltransferase activity double-stranded RNA binding ligase activity zinc ion binding | Escherichia coli | 3D-structure Ligase Metal-binding Reference proteome Zinc Zinc-finger | MAKNTSCGVQ | MAKNTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGDGVEVRLREDPETFLVQLYQHCPPLARIDSVEREPFIWSQLPTEFTIRQSTGGTMNTQIVPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCPACDKEYRDPLDRRFHAQPVACPECGPHLEWVSHGEHAEQEAALQAAIAQLKMGKIVAIKGIGGFHLACDARNSNAVATLRARKHRPAKPLAVMLPVADGLPDAARQLLTTPAAPIVLVDKKYVPELCDDIAPDLNEVGVMLPANPLQHLLLQELQCPLVM... | protein maturation protein-containing complex assembly ATPase complex carboxyl- or carbamoyltransferase activity double-stranded RNA binding ligase activity zinc ion binding Escherichia coli 3D-structure Ligase Metal-binding Reference proteome Zinc Zinc-finger MAKNTSCGVQ MAKNTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGDGVEV... |
thiamine biosynthetic process thiamine diphosphate biosynthetic process thiazole biosynthetic process | adenylyltransferase complex; cytoplasm; cytosol; sulfurtransferase complex | AMPylase activity ATP binding nucleotidyltransferase activity protein homodimerization activity sulfotransferase activity thiosulfate sulfurtransferase activity ubiquitin-like modifier activating enzyme activity zinc ion binding | Escherichia coli | 3D-structure ATP-binding Metal-binding Nucleotide-binding Nucleotidyltransferase Reference proteome Thiamine biosynthesis Thioester bond Transferase Zinc | MNDRDFMRYS | MNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAALYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDIDRPKSQVSQQRLTQLNPDIQLTALQQRLTGEALKDAVARADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQLMVLTPPWEQGCYRCLWPDNQEPERNCRTAGVVGPVVGVMGTLQALEAIKLLSGIETPAGELRLFDGKSSQWRSLALRRASGCPVCGGSNADPV | thiamine biosynthetic process thiamine diphosphate biosynthetic process thiazole biosynthetic process adenylyltransferase complex; cytoplasm; cytosol; sulfurtransferase complex AMPylase activity ATP binding nucleotidyltransferase activity protein homodimerization activity sulfotransferase activity thiosulfate sulfurtra... |
thiamine biosynthetic process thiamine diphosphate biosynthetic process | 2-iminoacetate synthase complex; cytosol | thiazole synthase activity | Escherichia coli | Cytoplasm Direct protein sequencing Reference proteome Schiff base Thiamine biosynthesis Transferase | MLRIADKTFD | MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKRVDLRQHNDAILEPLIAAGVTLLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHPDARWLLPDPIETLKAAETLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQGLETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAKAFRLAVEAGLLARQSGPGSRSYFAHATSPLTGFLEASA | thiamine biosynthetic process thiamine diphosphate biosynthetic process 2-iminoacetate synthase complex; cytosol thiazole synthase activity Escherichia coli Cytoplasm Direct protein sequencing Reference proteome Schiff base Thiamine biosynthesis Transferase MLRIADKTFD MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKRVDLRQHN... |
DNA damage response thiamine biosynthetic process thiamine diphosphate biosynthetic process | 2-iminoacetate synthase complex | 2-iminoacetate synthase activity 4 iron, 4 sulfur cluster binding iron ion binding | Escherichia coli | 4Fe-4S Direct protein sequencing Iron Iron-sulfur Lyase Metal-binding NADP Reference proteome S-adenosyl-L-methionine Thiamine biosynthesis | MKTFSDRWRQ | MKTFSDRWRQLDWDDIRLRINGKTAADVERALNASQLTRDDMMALLSPAASGYLEQLAQRAQRLTRQRFGNTVSFYVPLYLSNLCANDCTYCGFSMSNRIKRKTLDEADIARESAAIREMGFEHLLLVTGEHQAKVGMDYFRRHLPALREQFSSLQMEVQPLAETEYAELKQLGLDGVMVYQETYHEATYARHHLKGKKQDFFWRLETPDRLGRAGIDKIGLGALIGLSDNWRVDSYMVAEHLLWLQQHYWQSRYSVSFPRLRPCTGGIEPASIMDERQLVQTICAFRLLAPEIELSLSTRESPWFRDRVIPLAINNVSA... | DNA damage response thiamine biosynthetic process thiamine diphosphate biosynthetic process 2-iminoacetate synthase complex 2-iminoacetate synthase activity 4 iron, 4 sulfur cluster binding iron ion binding Escherichia coli 4Fe-4S Direct protein sequencing Iron Iron-sulfur Lyase Metal-binding NADP Reference proteome S-... |
apoptotic process ceramide metabolic process chromosome segregation female meiotic nuclear division meiotic sister chromatid cohesion, centromeric meiotic spindle elongation mitotic sister chromatid separation negative regulation of cell growth negative regulation of MAPK cascade negative regulation of phosphatidylinos... | chromosome, centromeric region; cytoplasm; cytosol; dendrite; extracellular exosome; glutamatergic synapse; lateral plasma membrane; membrane; microtubule cytoskeleton; mitochondrion; neuron projection; neuronal cell body; nucleus; protein phosphatase type 2A complex | protein antigen binding protein heterodimerization activity protein phosphatase regulator activity protein serine/threonine phosphatase activity | Homo sapiens | 3D-structure Acetylation Cell membrane Cell projection Centromere Chromosome Chromosome partition Cytoplasm Direct protein sequencing Disease variant Host-virus interaction Intellectual disability Membrane Nucleus Reference proteome Repeat | MAAADGDDSL | MAAADGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCREN... | apoptotic process ceramide metabolic process chromosome segregation female meiotic nuclear division meiotic sister chromatid cohesion, centromeric meiotic spindle elongation mitotic sister chromatid separation negative regulation of cell growth negative regulation of MAPK cascade negative regulation of phosphatidylinos... |
apoptotic process involved in morphogenesis positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | cytoplasm; extracellular exosome; membrane raft; protein phosphatase type 2A complex | protein phosphatase regulator activity | Homo sapiens | Acetylation Alternative splicing Reference proteome Repeat | MAGASELGTG | MAGASELGTGPGAAGGDGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQEHTPVALEAYFVPLVKRLASGDWFTSRTSACGLFSVCYPRASNAVKAEIRQQFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKE... | apoptotic process involved in morphogenesis positive regulation of extrinsic apoptotic signaling pathway in absence of ligand cytoplasm; extracellular exosome; membrane raft; protein phosphatase type 2A complex protein phosphatase regulator activity Homo sapiens Acetylation Alternative splicing Reference proteome Repea... |
chromosome segregation DNA replication DNA topological change | chromosome; nucleolus; nucleus | DNA binding DNA topoisomerase type I (single strand cut, ATP-independent) activity | Arabidopsis thaliana | Alternative splicing Coiled coil DNA-binding Isomerase Nucleus Phosphoprotein Reference proteome Topoisomerase | MGTETVSKPV | MGTETVSKPVMDNGSGDSDDDKPLAFKRNNTVASNSNQSKSNSQRSKAVPTTKVSPMRSPVTSPNGTTPSNKTSIVKSSMPSSSSKASPAKSPLRNDMPSTVKDRSQLQKDQSECKIEHEDSEDDRPLSSILSGNKGPTSSRQVSSPQPEKKNNGDRPLDRASRIIKDESDDETPISSMFRKKIDSGMSGGNQLSNDEKKPLVQKLHQNGSTVKNEVPNGKVLGKRPLEKNSSADQSSLKKAKISASPTSVKMKQDSVKKEIDDKGRVLVSPKMKAKQLSTREDGTDDDDDDDVPISKRFKSDSSNSNTSSAKPKAVKLN... | chromosome segregation DNA replication DNA topological change chromosome; nucleolus; nucleus DNA binding DNA topoisomerase type I (single strand cut, ATP-independent) activity Arabidopsis thaliana Alternative splicing Coiled coil DNA-binding Isomerase Nucleus Phosphoprotein Reference proteome Topoisomerase MGTETVSKPV M... |
proteolysis | chloroplast stroma; cytosol; vacuole | aminopeptidase activity dipeptidase activity manganese ion binding metalloaminopeptidase activity | Arabidopsis thaliana | Alternative splicing Aminopeptidase Cytoplasm Hydrolase Manganese Metal-binding Protease Reference proteome | MAHTLGLTQP | MAHTLGLTQPNSTEPHKISFTAKEIDVIEWKGDILVVGVTEKDLAKDGNSKFENPILSKVDAHLSGLLAQVSSEEDFTGKPGQSTVLRLPGLGSKRIALIGLGQSVSSPVAFHSLGEAVATVSKASQSTSAAIVLASSVSDESKLSSVSALASGIVLGLFEDGRYKSESKKPSLKAVDIIGFGTGAEVEKKLKYAEDVSYGVIFGRELINSPANVLTPAVLAEEAAKVASTYSDVFTANILNEEQCKELKMGSYLAVAAASANPPHFIHLVYKPPNGSVKTKLALVGKGLTFDSGGYNIKTGPGCSIELMKFDMGGSAAV... | proteolysis chloroplast stroma; cytosol; vacuole aminopeptidase activity dipeptidase activity manganese ion binding metalloaminopeptidase activity Arabidopsis thaliana Alternative splicing Aminopeptidase Cytoplasm Hydrolase Manganese Metal-binding Protease Reference proteome MAHTLGLTQP MAHTLGLTQPNSTEPHKISFTAKEIDVIEWKGD... |
chromosome condensation chromosome segregation DNA replication DNA topological change instar larval development oogenesis regulation of embryonic development | cytoplasm; cytosol; euchromatin; nucleolus; nucleus; polytene chromosome; polytene chromosome puff | DNA binding DNA topoisomerase activity DNA topoisomerase type I (single strand cut, ATP-independent) activity | Drosophila melanogaster | Cytoplasm DNA-binding Isomerase Nucleus Phosphoprotein Reference proteome Topoisomerase | MSGDVAAENS | MSGDVAAENSIHIQNGGSCEVVQSNGVTTNGHGHHHHHHSSSSSSSKHKSSSKDKHRDREREHKSSNSSSSSKEHKSSSRDKDRHKSSSSSSKHRDKDKERDGSSNSHRSGSSSSHKDKDGSSSSKHKSSSGHHKRSSKDKERRDKDKDRGSSSSSRHKSSSSSRDKERSSSSHKSSSSSSSSKSKHSSSRHSSSSSSKDHPSYDGVFVKPEPVSQQLMHSGSVDAFQMQQLGSYEAAAAGTNFNGNGNVAGANYKNGYEESIVDIKKEEESFNNLSQASSCDYSMSQFRADEPPFVVKHEQSYAEEDSTMNYNDHDDDA... | chromosome condensation chromosome segregation DNA replication DNA topological change instar larval development oogenesis regulation of embryonic development cytoplasm; cytosol; euchromatin; nucleolus; nucleus; polytene chromosome; polytene chromosome puff DNA binding DNA topoisomerase activity DNA topoisomerase type I... |
chemical synaptic transmission chemical synaptic transmission, postsynaptic chloride transmembrane transport gamma-aminobutyric acid signaling pathway monoatomic ion transmembrane transport regulation of postsynaptic membrane potential synaptic transmission, GABAergic | cerebellar Golgi cell to granule cell synapse; chloride channel complex; dendrite; dendrite membrane; GABA-A receptor complex; GABA-ergic synapse; hippocampal mossy fiber to CA3 synapse; neuron projection; neuronal cell body membrane; postsynapse; postsynaptic membrane; postsynaptic specialization membrane; presynaptic... | chloride channel activity diazepam binding GABA-A receptor activity heterocyclic compound binding inhibitory extracellular ligand-gated monoatomic ion channel activity neurotransmitter receptor activity protein-containing complex binding transmitter-gated monoatomic ion channel activity involved in regulation of postsy... | Rattus norvegicus | Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MLLLLPWLFS | MLLLLPWLFSLLWIENAQAQLEDEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFKGPAEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRLMHNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIE... | chemical synaptic transmission chemical synaptic transmission, postsynaptic chloride transmembrane transport gamma-aminobutyric acid signaling pathway monoatomic ion transmembrane transport regulation of postsynaptic membrane potential synaptic transmission, GABAergic cerebellar Golgi cell to granule cell synapse; chlo... |
acute inflammatory response to antigenic stimulus adaptive immune response heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules immunological synapse formation innate immune response lipopolysaccharide-mediated signaling pathway positive regulation of cytokine production involved in inflammatory ... | cell surface; extracellular region; immunological synapse; plasma membrane | identical protein binding lipopolysaccharide binding lipoteichoic acid binding protein kinase binding | Homo sapiens | 3D-structure Adaptive immunity Alternative splicing Cell adhesion Cell membrane Disulfide bond Glycoprotein Immunity Innate immunity Membrane Phosphoprotein Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix | MWLFFGITGL | MWLFFGITGLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPGQHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPH... | acute inflammatory response to antigenic stimulus adaptive immune response heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules immunological synapse formation innate immune response lipopolysaccharide-mediated signaling pathway positive regulation of cytokine production involved in inflammatory ... |
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