Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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amyloid-beta clearance cholesterol transport establishment of localization in cell lipoprotein transport negative regulation of gene expression phagocytosis, engulfment plasma lipoprotein particle clearance positive regulation of cholesterol storage positive regulation of macrophage derived foam cell differentiation re... | collagen trimer; low-density lipoprotein particle; plasma membrane | amyloid-beta binding cargo receptor activity low-density lipoprotein particle binding scavenger receptor activity | Mus musculus | 3D-structure Alternative splicing Coiled coil Collagen Disulfide bond Endocytosis Glycoprotein LDL Membrane Phosphoprotein Receptor Reference proteome Signal-anchor Transmembrane Transmembrane helix | MTKEMTENQR | MTKEMTENQRLCPHEQEDADCSSESVKFDARSMTASLPHSTKNGPSLQEKLKSFKAALIALYLLVFAVLIPVVGIVTAQLLNWEMKNCLVCSLNTSDTSQGPMEKENTSKVEMRFTIIMEHMKDMEERIESISNSKADLIDTERFQNFSMATDQRLNDILLQLNSLISSVQEHGNSLDAISKSLQSLNMTLLDVQLHTETLNVRVRESTAKQQEDISKLEERVYKVSAEVQSVKEEQAHVEQEVKQEVRVLNNITNDLRLKDWEHSQTLKNITFIQGPPGPQGEKGDRGLTGQTGPPGAPGIRGIPGVKGDRGQIGFPGG... | amyloid-beta clearance cholesterol transport establishment of localization in cell lipoprotein transport negative regulation of gene expression phagocytosis, engulfment plasma lipoprotein particle clearance positive regulation of cholesterol storage positive regulation of macrophage derived foam cell differentiation re... |
fusion of virus membrane with host plasma membrane viral life cycle | host cell plasma membrane; membrane; viral envelope; virion membrane | host cell surface receptor binding sialate 4-O-acetylesterase activity sialate 9-O-acetylesterase activity sialate O-acetylesterase activity | Human coronavirus OC43 | Disulfide bond Glycoprotein Hemagglutinin Host cell membrane Host membrane Hydrolase Membrane Reference proteome Signal Transmembrane Transmembrane helix Viral envelope protein Virion | MFLLPRFILV | MFLLPRFILVSCIIGSLGFYNPPTNVVSHVNGDWFLFGDSRSDCNHIVNINPHNYSYMDLNPVLCDSGKISSKAGNSIFRSFHFTDFYNYTGEGQQIIFYEGVNFTPYHAFKCNRSGSNDIWMQNKGLFYTQVYKNMAVYRSLTFVNVPYVYNGSAQSTALCKSGSLVLNNPAYIAPQANSGDYYYKVEADFYLSGCDEYIVPLCIFNGKFLSNTKYYDDSQYYFNKDTGVIYGLNSTETITTGFDLNCYYLVLPSGNYLAISNELLLTVPTKAICLNKRKDFTPVQVVDSRWNNARQSDNMTAVACQPPYCYFRNSTTN... | fusion of virus membrane with host plasma membrane viral life cycle host cell plasma membrane; membrane; viral envelope; virion membrane host cell surface receptor binding sialate 4-O-acetylesterase activity sialate 9-O-acetylesterase activity sialate O-acetylesterase activity Human coronavirus OC43 Disulfide bond Glyc... |
anaphase-promoting complex-dependent catabolic process cell division metaphase/anaphase transition of mitotic cell cycle protein K11-linked ubiquitination protein ubiquitination regulation of meiotic cell cycle regulation of mitotic cell cycle | anaphase-promoting complex; centrosome; cytoplasm; cytosol; mitotic spindle; nucleoplasm; nucleus; spindle | protein phosphatase binding | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Cytoskeleton Nucleus Phosphoprotein Reference proteome Repeat TPR repeat Ubl conjugation pathway | MTVLQEPVQA | MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRLLKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSLLGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCLPNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVISPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQNYTNTPPVIDVPSTGAPSKKS... | anaphase-promoting complex-dependent catabolic process cell division metaphase/anaphase transition of mitotic cell cycle protein K11-linked ubiquitination protein ubiquitination regulation of meiotic cell cycle regulation of mitotic cell cycle anaphase-promoting complex; centrosome; cytoplasm; cytosol; mitotic spindle;... |
cell division DNA strand elongation involved in DNA replication DNA synthesis involved in UV-damage excision repair mitotic DNA replication lagging strand elongation mitotic DNA replication leading strand elongation nucleotide-excision repair, DNA gap filling | cytosol; delta DNA polymerase complex; nucleus | DNA-directed DNA polymerase activity | Schizosaccharomyces pombe | Cell cycle Cell division DNA replication DNA-directed DNA polymerase Mitosis Nucleotidyltransferase Nucleus Phosphoprotein Reference proteome Transferase | MEEWRNFLDI | MEEWRNFLDIKVINESSLVTVDNLSLQLDISSEKAQEYLNMFYQGNDFLYPIYLIHGQPIDDEINLEIDEESQPISNFPVLQYILCDKSSLQEKQSRLKSGYKTVIFALSSAPLSDFDELLPAVYEIREKDVLYKKEDADKYGFIFNENSVPRVLKKAPSTHSPQLSVPSKTSTIDKTDTRSTEKTKGKDIFSNARNQKGNSSRKNKKAPLENHKEKEPLLPKEEKLSEQAKRERDDLKNIMQLEDESVSTTSVHDSEDDNLDSNNFQLEIGTEAKSAAPDEPQEIIKSVSGGKRRGKRKVKKYATTKDEEGFLVTKEEE... | cell division DNA strand elongation involved in DNA replication DNA synthesis involved in UV-damage excision repair mitotic DNA replication lagging strand elongation mitotic DNA replication leading strand elongation nucleotide-excision repair, DNA gap filling cytosol; delta DNA polymerase complex; nucleus DNA-directed ... |
antigen processing and presentation of exogenous peptide antigen via MHC class I antigen processing and presentation of exogenous peptide antigen via MHC class II cellular response to low-density lipoprotein particle stimulus defense response to bacterium Fc receptor mediated stimulatory signaling pathway Fc-epsilon re... | cell surface; external side of plasma membrane; Fc-epsilon receptor I complex; Fc-gamma receptor III complex; ficolin-1-rich granule membrane; plasma membrane; tertiary granule membrane | identical protein binding IgE binding IgE receptor activity IgG binding protein homodimerization activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond IgE-binding protein Immunity Innate immunity Membrane Phosphoprotein Receptor Reference proteome Signal Transmembrane Transmembrane helix | MIPAVVLLLL | MIPAVVLLLLLLVEQAAALGEPQLCYILDAILFLYGIVLTLLYCRLKIQVRKAAITSYEKSDGVYTGLSTRNQETYETLKHEKPPQ | antigen processing and presentation of exogenous peptide antigen via MHC class I antigen processing and presentation of exogenous peptide antigen via MHC class II cellular response to low-density lipoprotein particle stimulus defense response to bacterium Fc receptor mediated stimulatory signaling pathway Fc-epsilon re... |
negative regulation of apoptotic process negative regulation of protein binding phosphocreatine biosynthetic process phosphorylation | mitochondrial inner membrane; mitochondrial inner-outer membrane contact site; mitochondrion; myelin sheath; perikaryon | ATP binding creatine kinase activity identical protein binding | Mus musculus | ATP-binding Direct protein sequencing Kinase Membrane Mitochondrion Mitochondrion inner membrane Nucleotide-binding Phosphoprotein Reference proteome Transferase Transit peptide | MAGPFSRLLS | MAGPFSRLLSARPGLRLLALAGAGSLTAGILLRPESVGAAAAERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFAELFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVEKLIQERGWEFMWNERLGYILTCPSN... | negative regulation of apoptotic process negative regulation of protein binding phosphocreatine biosynthetic process phosphorylation mitochondrial inner membrane; mitochondrial inner-outer membrane contact site; mitochondrion; myelin sheath; perikaryon ATP binding creatine kinase activity identical protein binding Mus ... |
cell division G2/MI transition of meiotic cell cycle in utero embryonic development mitotic cell cycle phase transition regulation of growth spindle assembly involved in female meiosis I T cell homeostasis thymus development | centrosome; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; cytosol; membrane; microtubule cytoskeleton; nucleus | cyclin-dependent protein serine/threonine kinase regulator activity | Mus musculus | Cell cycle Cell division Cyclin Mitosis Phosphoprotein Reference proteome | MALLRRPTVS | MALLRRPTVSSDLKNIDTEVIPKAKSHVTIRRAVLEEIGNKVRNRTTQVAKKPQNTKVPALPTKVTNVNKQPKPTASVKPVQMEALAPKDRPPAPEDVSMKEESLCQAFSDALLCKIEDIDNEDRENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQLVCRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVL... | cell division G2/MI transition of meiotic cell cycle in utero embryonic development mitotic cell cycle phase transition regulation of growth spindle assembly involved in female meiosis I T cell homeostasis thymus development centrosome; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; cytosol; membrane; m... |
adult locomotory behavior cell division cellular response to X-ray G1/S transition of mitotic cell cycle long-term memory mitotic cell cycle phase transition negative regulation of apoptotic process positive regulation of cell population proliferation positive regulation of cyclin-dependent protein serine/threonine kin... | chromatin; cyclin D2-CDK4 complex; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; cytosol; nuclear membrane; nucleolus; nucleoplasm; nucleus | cyclin-dependent protein serine/threonine kinase activator activity cyclin-dependent protein serine/threonine kinase regulator activity protein kinase binding | Homo sapiens | 3D-structure Alternative splicing Cell cycle Cell division Cyclin Cytoplasm Disease variant Membrane Nucleus Phosphoprotein Reference proteome Ubl conjugation | MELLCHEVDP | MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL | adult locomotory behavior cell division cellular response to X-ray G1/S transition of mitotic cell cycle long-term memory mitotic cell cycle phase transition negative regulation of apoptotic process positive regulation of cell population proliferation positive regulation of cyclin-dependent protein serine/threonine kin... |
adult locomotory behavior cell division cellular response to X-ray G1/S transition of mitotic cell cycle long-term memory mitotic cell cycle phase transition negative regulation of apoptotic process negative regulation of cardiac muscle cell differentiation positive regulation of cardiac muscle cell proliferation posit... | chromatin; cyclin D2-CDK4 complex; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; cytosol; nuclear membrane; nucleolus; nucleoplasm; nucleus | cyclin-dependent protein serine/threonine kinase activator activity cyclin-dependent protein serine/threonine kinase regulator activity protein kinase binding | Mus musculus | Cell cycle Cell division Cyclin Cytoplasm Membrane Nucleus Phosphoprotein Reference proteome Ubl conjugation | MELLCCEVDP | MELLCCEVDPVRRAVPDRNLLEDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSVKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQKEKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDDEVNTLTCDALTELLAKITHTDVDCLKACQEQIEALLLNSLQQFRQEQHNAGSKSVEDPDQATTPTDVRDVDL | adult locomotory behavior cell division cellular response to X-ray G1/S transition of mitotic cell cycle long-term memory mitotic cell cycle phase transition negative regulation of apoptotic process negative regulation of cardiac muscle cell differentiation positive regulation of cardiac muscle cell proliferation posit... |
cell division G1/S transition of mitotic cell cycle mitotic cell cycle phase transition negative regulation of transcription by RNA polymerase II positive regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of protein phosphorylation regulation of cell population proliferation si... | cyclin D3-CDK4 complex; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; cytosol; nucleoplasm; nucleus | cyclin-dependent protein serine/threonine kinase activator activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase regulator activity protein kinase binding | Homo sapiens | 3D-structure Alternative splicing Cell cycle Cell division Cyclin Cytoplasm Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MELLCCEGTR | MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL | cell division G1/S transition of mitotic cell cycle mitotic cell cycle phase transition negative regulation of transcription by RNA polymerase II positive regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of protein phosphorylation regulation of cell population proliferation si... |
cell division G1/S transition of mitotic cell cycle hyaluronan biosynthetic process mitotic cell cycle phase transition negative regulation of transcription by RNA polymerase II positive regulation of cell population proliferation positive regulation of protein phosphorylation regulation of cell cycle regulation of cel... | cyclin D3-CDK4 complex; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleoplasm; nucleus | cyclin-dependent protein serine/threonine kinase activator activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase regulator activity protein kinase binding | Mus musculus | Cell cycle Cell division Cyclin Cytoplasm Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MELLCCEGTR | MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQKEIKPHMRKMLAYWMLEVCEEQRCEEDVFPLAMNYLDRYLSCVPTRKAQLQLLGTVCLLLASKLRETTPLTIEKLCIYTDQAVAPWQLREWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPSDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVLGLGACSMSADELTELLAGITGTEVDCLRACQEQIEAALRESLREAAQTAPSPVPKAPRGSSSQGPSQTSTPTDVTAIHL | cell division G1/S transition of mitotic cell cycle hyaluronan biosynthetic process mitotic cell cycle phase transition negative regulation of transcription by RNA polymerase II positive regulation of cell population proliferation positive regulation of protein phosphorylation regulation of cell cycle regulation of cel... |
cell division DNA damage response G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle mitotic cell cycle phase transition positive regulation of DNA replication positive regulation of mitotic spindle pole body separation premeiotic DNA replication regulation of DNA-templated transcription regula... | cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus; spindle pole body | cyclin-dependent protein serine/threonine kinase regulator activity | Saccharomyces cerevisiae | Cell cycle Cell division Cyclin Reference proteome | MGENHDHEQS | MGENHDHEQSIKRNSMIYNENERQLCNSNLKILQNKRALSKNDSSSKQQVQDSKPRRALTDVPVNNNPLSQNKRIVAGSKAAKVRREENIRPIVSAVQKRQIYNDRTAAEQEEEEEEEGEDDDAASIVNKKRRIDAEGVSEIVGWQDLDYVEKDDTAMVAEYSAEIFAFLYRRELETLPSHNYLLDKTSKYYLRPSMRTILVDWLVEVHEKFQCYPETLFLSINLMDRFLAKNKVTMNKLQLLAVTSLFIAAKFEEVNLPKLAEYAYITDGAASKNDIKNAEMFMLTSLEFNIGWPNPLNFLRRISKADDYDPVNRNIGK... | cell division DNA damage response G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle mitotic cell cycle phase transition positive regulation of DNA replication positive regulation of mitotic spindle pole body separation premeiotic DNA replication regulation of DNA-templated transcription regula... |
cell division cellular response to interleukin-4 cellular response to ionomycin cellular response to lipopolysaccharide cellular response to phorbol 13-acetate 12-myristate G1/S transition of mitotic cell cycle phosphorylation positive regulation of apoptotic process positive regulation of cell population proliferation... | bicellular tight junction; chromatin; cyclin D1-CDK4 complex; cyclin D2-CDK4 complex; cyclin D3-CDK4 complex; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; cytosol; nuclear membrane; nucleolus; nucleoplasm; nucleus; perinuclear region of cytoplasm; transcription regulator complex | ATP binding cyclin binding cyclin-dependent protein serine/threonine kinase activity kinase activity protein kinase activity protein serine kinase activity protein-containing complex binding | Mus musculus | Acetylation ATP-binding Cell cycle Cell division Cytoplasm Kinase Membrane Nucleotide-binding Nucleus Phosphoprotein Proto-oncogene Reference proteome Serine/threonine-protein kinase Transferase | MAATRYEPVA | MAATRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEAFEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRTYLDKAPPPGLPVETIKDLMRQFLSGLDFLHANCIVHRDLKPENILVTSNGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPREVSLPRGAFAPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKEESDAE | cell division cellular response to interleukin-4 cellular response to ionomycin cellular response to lipopolysaccharide cellular response to phorbol 13-acetate 12-myristate G1/S transition of mitotic cell cycle phosphorylation positive regulation of apoptotic process positive regulation of cell population proliferation... |
cell cycle cell division negative regulation of G2/M transition of mitotic cell cycle negative regulation of G2/MI transition of meiotic cell cycle phosphorylation signaling | cytoplasm; cytosol; nucleus | ATP binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity | Schizosaccharomyces pombe | ATP-binding Cell cycle Cell division Kinase Magnesium Metal-binding Mitosis Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase Tyrosine-protein kinase | MDSSTTIPIT | MDSSTTIPITPTRTPCFFNISSSFNEHSPLNFYDEPIYNFSSGHEENQSHKSSKLTFFKPSNTKRSPHTPMQNNAKAIRLSTTVRHGIFKNSDLDGCSKPFAFSSGLKLSKKIVDASTPIDLKRKRAVTSLSTGLLSKREKWSLWEGNLTNPRSEQPHTPCKKGTKIKLKPPQSPLSPTTSLLARKCKHIDLDTFSRLDHPNSDSSDETFEMEELPSLSYGSEDLLEFCETPCKSQPIFLSSSHVNNWDEKDVPSSLSWTPTSPIFLNINSADDYEEEEDWTSDLRIRFQQVKPIHESDFSFVYHVSSINPPTETVYVVK... | cell cycle cell division negative regulation of G2/M transition of mitotic cell cycle negative regulation of G2/MI transition of meiotic cell cycle phosphorylation signaling cytoplasm; cytosol; nucleus ATP binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity protein tyrosine... |
cell division establishment of cell polarity G2/M transition of mitotic cell cycle microtubule cytoskeleton organization negative regulation of G1/S transition of mitotic cell cycle negative regulation of G2/M transition of mitotic cell cycle neuron projection morphogenesis phosphorylation positive regulation of DNA re... | cytoplasm; nucleolus; nucleoplasm; nucleus | ATP binding magnesium ion binding non-membrane spanning protein tyrosine kinase activity protein tyrosine kinase activity | Homo sapiens | 3D-structure Alternative splicing ATP-binding Cell cycle Cell division Kinase Magnesium Metal-binding Mitosis Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transferase Tyrosine-protein kinase Ubl conjugation | MSFLSRQQPP | MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFGSSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFRKLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRL... | cell division establishment of cell polarity G2/M transition of mitotic cell cycle microtubule cytoskeleton organization negative regulation of G1/S transition of mitotic cell cycle negative regulation of G2/M transition of mitotic cell cycle neuron projection morphogenesis phosphorylation positive regulation of DNA re... |
gap junction-mediated intercellular transport lens development in camera-type eye positive regulation of cell adhesion protein homotetramerization response to stimulus visual perception water transport | apical plasma membrane; endoplasmic reticulum; gap junction; plasma membrane | calmodulin binding structural constituent of eye lens water channel activity | Homo sapiens | Cataract Cell junction Cell membrane Disease variant Eye lens protein Gap junction Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Repeat Sensory transduction Transmembrane Transmembrane helix Transport Vision | MWELRSASFW | MWELRSASFWRAIFAEFFATLFYVFFGLGSSLRWAPGPLHVLQVAMAFGLALATLVQSVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLYSVTPPAVRGNLALNTLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLLYDFLLFPRLKSISERLSVLKGAKPDVSNGQPEVTGEPVELNTQAL | gap junction-mediated intercellular transport lens development in camera-type eye positive regulation of cell adhesion protein homotetramerization response to stimulus visual perception water transport apical plasma membrane; endoplasmic reticulum; gap junction; plasma membrane calmodulin binding structural constituent... |
response to water deprivation | endoplasmic reticulum; plasma membrane | water channel activity | Arabidopsis thaliana | Acetylation Cell membrane Membrane Phosphoprotein Reference proteome Repeat Stress response Transmembrane Transmembrane helix Transport | MAKDVEGPDG | MAKDVEGPDGFQTRDYEDPPPTPFFDAEELTKWSLYRAVIAEFVATLLFLYVTVLTVIGYKIQSDTKAGGVDCGGVGILGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLFLARKVSLIRAVLYMVAQCLGAICGVGFVKAFQSSHYVNYGGGANFLADGYNTGTGLAAEIIGTFVLVYTVFSATDPKRNARDSHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIFNKSKPWDDHWIFWVGPFIGATIAAFYHQFVLRASGSKSLGSFRSAANV | response to water deprivation endoplasmic reticulum; plasma membrane water channel activity Arabidopsis thaliana Acetylation Cell membrane Membrane Phosphoprotein Reference proteome Repeat Stress response Transmembrane Transmembrane helix Transport MAKDVEGPDG MAKDVEGPDGFQTRDYEDPPPTPFFDAEELTKWSLYRAVIAEFVATLLFLYVTVLTVIGY... |
cell division cell population proliferation cellular response to UV G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle positive regulation of DNA replication positive regulation of G2/M transition of mitotic cell cycle positive regulation of G2/MI transition of meiotic cell cycle regulation of ... | cytoplasm; cytosol; nucleoplasm; nucleus | phosphoprotein phosphatase activity protein kinase binding protein tyrosine phosphatase activity protein-folding chaperone binding | Homo sapiens | 3D-structure Alternative splicing Cell cycle Cell division Hydrolase Mitosis Phosphoprotein Protein phosphatase Reference proteome Ubl conjugation | MELGPEPPHR | MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYEQPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAPARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLAS... | cell division cell population proliferation cellular response to UV G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle positive regulation of DNA replication positive regulation of G2/M transition of mitotic cell cycle positive regulation of G2/MI transition of meiotic cell cycle regulation of ... |
cell division female meiosis I G2/M transition of mitotic cell cycle mitotic cell cycle oocyte maturation positive regulation of cell population proliferation positive regulation of cytokinesis positive regulation of G2/M transition of mitotic cell cycle positive regulation of G2/MI transition of meiotic cell cycle pos... | centrosome; cytoplasm; cytosol; nucleoplasm; nucleus; spindle pole | phosphoprotein phosphatase activity protein kinase binding protein tyrosine phosphatase activity | Homo sapiens | 3D-structure Alternative splicing Cell cycle Cell division Cytoplasm Cytoskeleton Hydrolase Mitosis Phosphoprotein Protein phosphatase Reference proteome | MEVPQPEPAP | MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFR... | cell division female meiosis I G2/M transition of mitotic cell cycle mitotic cell cycle oocyte maturation positive regulation of cell population proliferation positive regulation of cytokinesis positive regulation of G2/M transition of mitotic cell cycle positive regulation of G2/MI transition of meiotic cell cycle pos... |
cell division female meiosis I G2/M transition of mitotic cell cycle oocyte maturation positive regulation of cytokinesis positive regulation of G2/M transition of mitotic cell cycle positive regulation of G2/MI transition of meiotic cell cycle positive regulation of mitotic cell cycle | centrosome; cytoplasm; nucleus; spindle pole | phosphoprotein phosphatase activity protein kinase binding protein tyrosine phosphatase activity | Mus musculus | Cell cycle Cell division Cytoplasm Cytoskeleton Hydrolase Mitosis Phosphoprotein Protein phosphatase Reference proteome | MEVPLQKSAP | MEVPLQKSAPGSALSPARVLGGIQRPRHLSVFEFESDGFLGSPEPTASSSPVTTLTQTMHNLAGLGSEPPKAQVGSLSFQNRLADLSLSRRTSECSLSSESSESSDAGLCMDSPSPVDPQMAERTFEQAIQAASRVIQNEQFTIKRFRSLPVRLLEHSPVLQSITNSRALDSWRKTEAGYRAAANSPGEDKENDGYIFKMPQELPHSSSAQALAEWVSRRQAFTQRPSSAPDLMCLTTEWKMEVEELSPVAQSSSLTPVERASEEDDGFVDILESDLKDDEKVPAGMENLISAPLVKKLDKEEEQDLIMFSKCQRLFRSP... | cell division female meiosis I G2/M transition of mitotic cell cycle oocyte maturation positive regulation of cytokinesis positive regulation of G2/M transition of mitotic cell cycle positive regulation of G2/MI transition of meiotic cell cycle positive regulation of mitotic cell cycle centrosome; cytoplasm; nucleus; s... |
cell division cell population proliferation G2/M transition of mitotic cell cycle positive regulation of G2/M transition of mitotic cell cycle positive regulation of G2/MI transition of meiotic cell cycle regulation of cyclin-dependent protein serine/threonine kinase activity regulation of mitotic nuclear division sper... | cytoplasm; cytosol; mitochondrial intermembrane space; nucleoplasm; nucleus; perinuclear region of cytoplasm | phosphoprotein phosphatase activity protein kinase binding protein tyrosine phosphatase activity WW domain binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Cell cycle Cell division Host-virus interaction Hydrolase Mitosis Nucleus Phosphoprotein Protein phosphatase Reference proteome | MSTELFSSTR | MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANLSILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMKCSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQG... | cell division cell population proliferation G2/M transition of mitotic cell cycle positive regulation of G2/M transition of mitotic cell cycle positive regulation of G2/MI transition of meiotic cell cycle regulation of cyclin-dependent protein serine/threonine kinase activity regulation of mitotic nuclear division sper... |
antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to interleukin-1 cellular response to lipopolysaccharide chemokine-mediated signaling pathway inflammatory response leukocyte chemotaxis neutrophil chemotaxis positive regulation of cytosolic calcium ion concentration response to ... | extracellular space | chemokine activity CXCR chemokine receptor binding | Rattus norvegicus | Chemotaxis Cytokine Direct protein sequencing Disulfide bond Inflammatory response Reference proteome Secreted Signal | MAPPTRQLLN | MAPPTRQLLNAVLVLLLLLATNHQGTGVVVASELRCQCLTTLPRVDFKNIQSLTVTPPGPHCAQTEVIATLKDGHEVCLNPEAPLVQRIVQKILNKGKAN | antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to interleukin-1 cellular response to lipopolysaccharide chemokine-mediated signaling pathway inflammatory response leukocyte chemotaxis neutrophil chemotaxis positive regulation of cytosolic calcium ion concentration response to ... |
leukotriene biosynthetic process leukotriene metabolic process peptide catabolic process protein metabolic process proteolysis response to peptide hormone response to zinc ion type I pneumocyte differentiation | cytosol; nucleoplasm; nucleus | aminopeptidase activity epoxide hydrolase activity leukotriene-A4 hydrolase activity metalloaminopeptidase activity tripeptide aminopeptidase activity zinc ion binding | Rattus norvegicus | Acetylation Cytoplasm Hydrolase Leukotriene biosynthesis Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Zinc | MPEVADTCSL | MPEVADTCSLASPASVCRTQHLHLRCSVDFARRALTGTAALTVQSQEDNLRSLTLDTKDLTIEKVVINGQEVKYTLGESQGYKGSPMEISLPIALSKNQEVVIEISFETSPKSSALQWLTPEQTSGKQHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGEAPDPEDPSRKIYRFNQRVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEG... | leukotriene biosynthetic process leukotriene metabolic process peptide catabolic process protein metabolic process proteolysis response to peptide hormone response to zinc ion type I pneumocyte differentiation cytosol; nucleoplasm; nucleus aminopeptidase activity epoxide hydrolase activity leukotriene-A4 hydrolase acti... |
cellular response to calcium ion leukotriene biosynthetic process leukotriene production involved in inflammatory response lipoxygenase pathway positive regulation of acute inflammatory response protein homotrimerization | endoplasmic reticulum; endoplasmic reticulum membrane; nuclear envelope; nuclear membrane; nucleus | arachidonate 5-lipoxygenase activity arachidonic acid binding enzyme activator activity enzyme binding glutathione peroxidase activity glutathione transferase activity identical protein binding leukotriene-C4 synthase activity protein-containing complex binding | Mus musculus | Endoplasmic reticulum Leukotriene biosynthesis Membrane Nucleus Reference proteome Transmembrane Transmembrane helix | MDQEAVGNVV | MDQEAVGNVVLLALVTLISVVQNAFFAHKVEHESKAHNGRSFQRTGTLAFERVYTANQNCVDAYPTFLVVLWTAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSFAGILNHYLIFFFGSDFENYIRTVSTTISPLLLIP | cellular response to calcium ion leukotriene biosynthetic process leukotriene production involved in inflammatory response lipoxygenase pathway positive regulation of acute inflammatory response protein homotrimerization endoplasmic reticulum; endoplasmic reticulum membrane; nuclear envelope; nuclear membrane; nucleus ... |
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger presynaptic modulation of chemical synaptic transm... | cholinergic synapse; dendrite; plasma membrane; postsynaptic membrane; presynapse; synapse | arrestin family protein binding G protein-coupled acetylcholine receptor activity G protein-coupled serotonin receptor activity | Gallus gallus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix | MNNSTYINSS | MNNSTYINSSSENVIALESPYKTIEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGIFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGGRTVPDKDCYIQFFSNPAVTFGTAIAAFYLPVIIMTVLYWQISRASKSRIKKGKKEAAQNQDPVSPSLVQGKIVKPNNNNIPTSSDGLEHNKVQNGKTTGESVMENCVQGEEKDSSNDSTSVSVVPSNTKEDEAAKDASQISASQDHLKV... | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger presynaptic modulation of chemical synaptic transm... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Gorilla gorilla gorilla | Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MAVMAPRTLV | MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDRNTRNVKAHSQTDRVDLGTLRGYYNQSEDGSHTIQRMYGCDVGSDGRFLRGYQQDAYDGKDYIALNEDLRSWTAADMAAEITKRKWEAAHFAEQLRAYLEGTCVEWLRRHLENGKETLQRTDAPKTHMTHHAVSDHEAILRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPEPLTLRWEPSSQPTIPIVGIIAGLVLFGA... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Gorilla gorilla gorilla | Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MAVMAPRTLL | MAVMAPRTLLLLLLGALALTQTWAGSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEEPEYWDGETRKVKAHSQTDRVNLGTLRGYYNQSEAGSHTIQKMYGCDVGSDGRFLRGYQQDAYDGKDYIALNEDLRSWTAADMAAEITKRKWEAAHFAEQLRAYLEGECVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAILRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHESLPKPLTLRWEPSSQPTIPIVGIIAGLVLFGA... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Gorilla gorilla gorilla | Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MAVMAPRTLV | MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEEPEYWDGETRNMKARSQTDRVDLGTLRGYYNQSEDGSHTIQRMYGCDVGSDGRFLRGYQQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWEAAHEAEQLRAYLEGTCVEWLRRYLENGKETLQLTDAPKTHMTHHPVSDHEAILRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEPSSQPTIPIVGIIAGLVLFGA... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Gorilla gorilla gorilla | Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MAVVAPRTLL | MAVVAPRTLLLLLSGALALTQTWAGSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWMEQEEPEYWDRQTQISKTNAQIELESLRIALRYYNQSEDGSHTIQRMYGCDVGSDGRFLRGYQQDAYDGKDYIASNEDLRSWTAADMAAEITKRKWEAAHFAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHTTHQAVSDHEATLKCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEPSSQPTIPIVGIIAGLVLFGA... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Gorilla gorilla gorilla | Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MRVTAPRTLL | MRVTAPRTLLLLLSAALALTETWAGSHSMRYFDTAVSRPGRGEPRFITVGYVDDTQFVRFDSDAASPRMEPRAPWIEQEGPEYWDRETQTSKAQAQTDRENLRIALRYYNQSEAGSHTIQRMFGCDVGPDGRLLRGYSQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAREAEQLRAYLEGTCVEWLRRYLENGRETLQRADTPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEERYTCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLAV... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Gorilla gorilla gorilla | Disulfide bond Glycoprotein Immunity Membrane MHC I Reference proteome Signal Transmembrane Transmembrane helix | MRVTAPRTLL | MRVTAPRTLLLLLSAALALTETWAGSHSMRYFDTAVSRPGRGEPRFITVGYVDDTQFVRFDSDAASPRMEPRAPWIEQEGPEYWDRETQTSKAQAQTDRENLRIALRYYNQSEAGSHTFQRMFGCDVGPDGRLLRGYSQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAREAEQLRAYLEGTCVEWLRRYLENGRETLQRADTPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEERYTCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLAV... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Gorilla gorilla gorilla | Disulfide bond Glycoprotein Immunity Membrane MHC I Reference proteome Signal Transmembrane Transmembrane helix | MRVTAPRTLL | MRVTAPRTLLLLLSAALALTETWAGSHSMRYFDTAVSRPGRGEPRFITVGYVDDTQFVRFDSDAASPRMEPRAPWIEQEGPEYWDRETQTSKAQAQTDRENLRIALRYYNQSEAGSHTIQWMYGCDMGPDGRLLRGYSQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAREAEQLRAYLEGTCVEWLRRYLENGRETLQRADTPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEERYTCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLAV... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Gorilla gorilla gorilla | Disulfide bond Glycoprotein Immunity Membrane MHC I Reference proteome Signal Transmembrane Transmembrane helix | MQVTAPRTLL | MQVTAPRTLLLLLSAALALTETWAGSHSMRYFHTAMSRPGRGEPRFITVGYVDDTQFVWFDSDAASPRKEPRTPWIEQEGPEYWDRETQISKTNTQTYRVGLGTLRGYYNQSEDGSHTIQRMYGCDMGPDGRLLRGYSQLAYDGKDYLALNEDLSSWTAADTAAQITQRKWEAARAAEQERAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCRVQHEGLPEPLTLRWEPSSQSTIPIVGIVAGLAVLVV... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Gorilla gorilla gorilla | Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MRVMAPRTLI | MRVMAPRTLILLLSGALALTETWAGSHSMRYFFTAVAPPGRGEPRFIAVGYVDDTQFVRFDSDAANTRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRVSLRKLRGYYNQSEDGSHTFQRMYGCDVGPDGRLQRGYDQLAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAARWAERQRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQTQDIELVETRPAGDGTFQKWAAMVVPSGEEQRYTCHVQHKGLLEPLTLRWEPSSQPTIPIVGIVAGLAVLAV... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Gorilla gorilla gorilla | Disulfide bond Glycoprotein Immunity Membrane MHC I Reference proteome Signal Transmembrane Transmembrane helix | MRVMAPRTLI | MRVMAPRTLILPLSGALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRVNLRKLRGYYNQSEDGSHTLQSMYGCDLGPDGRLLRGYSQFAYDGKDYIALNEDLRSWTAADTAAQVTQRKWEAARVAEQERAYLEGLCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLPEPLTLRWEPSSQPTIPIVGIVVGLAVLVV... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Gorilla gorilla gorilla | Disulfide bond Glycoprotein Immunity Membrane MHC I Reference proteome Signal Transmembrane Transmembrane helix | MRVMAPRTLI | MRVMAPRTLILLLSGALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRVNLRKLRGYYNQSEDGSHTLQSMYGCDLGPDGRLLRGYSQFAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQQRAYLEGLCVESLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLPEPLTLRWEPSSQPTIPIVGIVVGLAVLVV... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Gorilla gorilla gorilla | Disulfide bond Glycoprotein Immunity Membrane MHC I Reference proteome Signal Transmembrane Transmembrane helix | MRVMAPRTLI | MRVMAPRTLILLLSGALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRVNLRKLRGYYNQSEDGSHTLQSMYGCDLGPDGRLLRGYSQFAYDGKDYIALNEDLRSWTAADTAAQVTQRKWEAARVAEQERAYLEGLCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLPEPLTLRWEPSSQPTIPIVGIVVGLAVLVV... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Gorilla gorilla gorilla | Disulfide bond Glycoprotein Immunity Membrane MHC I Reference proteome Signal Transmembrane Transmembrane helix | MAVVAPRTLL | MAVVAPRTLLLLLSGTLALTRTWAGSHSMRYFYTTMSRPGRGEPRFISVGYVDDTQFVRFDSDDASPREEPRAPWMEREGPEYWDRNTQIYKAQAQTDRVDLETLRGYYNQSEGGSHTIQRMYGCEVGPDGRFLRGYLQDAYDGKDYITLNEDLRSWTAADMAAQITQRKWEAAREAERLRAYMEGTCVEWLRRHLENGKETLQRTDPPKTHMTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPGGDGTFQKWAAVVVPSGKEQRYTCHVQHEGLPKPLTLRWEPSSQPTIPIVGIIAGLVLLGA... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
proteolysis | extracellular region | metal ion binding metalloendopeptidase activity toxin activity | Calloselasma rhodostoma | 3D-structure Cell adhesion impairing toxin Direct protein sequencing Disulfide bond Glycoprotein Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Platelet aggregation inhibiting toxin Protease Secreted Signal Toxin Zinc Zymogen | MIQVLLVTIC | MIQVLLVTICLAAFPYQGSSIILESGNVNDYEVVYPRKVIALSEGAAQQKYEDTMQYEFKVNGEPVVLHLEKNKGLFAKDYSETHYSPDGTRITTYPSVEDHCYYQGRIHNDADSTASISACNGLKGHFKLQGETYFIEPMKLPDSEAHAVFKYENIEKEDESPKMCGVTETNWESDEPIKKVSQLNLNHEIKRHVDIVVVVDSRFCTKHSNDLEVIRKFVHEVVNAIIESYKYMHFGISLVNLETWCNGDLINVQEDSYETLKAFGKWRESDLIKHVNHSNAQFLMDMKFIKNIIGKAYLDSICDPERSVGIVQNYHGI... | proteolysis extracellular region metal ion binding metalloendopeptidase activity toxin activity Calloselasma rhodostoma 3D-structure Cell adhesion impairing toxin Direct protein sequencing Disulfide bond Glycoprotein Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Platelet aggregation inhibiting tox... |
apoptotic process cellular response to arsenic-containing substance cellular response to calcium ion cellular response to hydrogen peroxide mitochondrial outer membrane permeabilization involved in programmed cell death negative regulation of apoptotic process negative regulation of ATP-dependent activity negative regu... | cytoplasm; mitochondrial matrix; mitochondrial permeability transition pore complex; mitochondrion | cyclosporin A binding peptidyl-prolyl cis-trans isomerase activity | Bos taurus | Acetylation Apoptosis Direct protein sequencing Isomerase Mitochondrion Necrosis Reference proteome Rotamase S-nitrosylation Transit peptide | MMLALRCGPR | MMLALRCGPRLLGLLSGPRSAHLRLPAVRACSSGSGSHGSSSSSGNPLVYLDVGADGQPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFKLKHEGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGKTSKKIVITDCGQLS | apoptotic process cellular response to arsenic-containing substance cellular response to calcium ion cellular response to hydrogen peroxide mitochondrial outer membrane permeabilization involved in programmed cell death negative regulation of apoptotic process negative regulation of ATP-dependent activity negative regu... |
apoptotic mitochondrial changes cellular response to arsenic-containing substance cellular response to calcium ion cellular response to hydrogen peroxide mitochondrial depolarization mitochondrial outer membrane permeabilization involved in programmed cell death necroptotic process negative regulation of apoptotic proc... | cytoplasm; membrane; mitochondrial inner membrane; mitochondrial matrix; mitochondrial permeability transition pore complex; mitochondrion | cyclosporin A binding peptidyl-prolyl cis-trans isomerase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Apoptosis Isomerase Mitochondrion Necrosis Reference proteome Rotamase S-nitrosylation Transit peptide | MLALRCGSRW | MLALRCGSRWLGLLSVPRSVPLRLPAARACSKGSGDPSSSSSSGNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS | apoptotic mitochondrial changes cellular response to arsenic-containing substance cellular response to calcium ion cellular response to hydrogen peroxide mitochondrial depolarization mitochondrial outer membrane permeabilization involved in programmed cell death necroptotic process negative regulation of apoptotic proc... |
arachidonic acid secretion blood circulation cell surface receptor signaling pathway G protein-coupled receptor signaling pathway inflammatory response intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator negative regulation of intrinsic apoptotic signaling pathway in response to os... | endosome; Golgi apparatus; intracellular membrane-bounded organelle; plasma membrane | bradykinin receptor activity phosphatidylinositol phospholipase C activity protease binding protein heterodimerization activity type 1 angiotensin receptor binding | Homo sapiens | 3D-structure Alternative splicing Cell membrane Direct protein sequencing Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MFSPWKISMF | MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQPPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNNFDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVITFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGILSSCQDERIIDVITQIASFM... | arachidonic acid secretion blood circulation cell surface receptor signaling pathway G protein-coupled receptor signaling pathway inflammatory response intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator negative regulation of intrinsic apoptotic signaling pathway in response to os... |
androgen receptor signaling pathway chaperone-mediated protein folding copper ion transport embryo implantation male sex differentiation negative regulation of microtubule polymerization negative regulation of microtubule polymerization or depolymerization negative regulation of neuron projection development prostate g... | axonal growth cone; cytoplasm; cytosol; microtubule; mitochondrion; neuronal cell body; nucleoplasm; nucleus; perinuclear region of cytoplasm; protein-containing complex | ATP binding copper-dependent protein binding GTP binding heat shock protein binding nuclear glucocorticoid receptor binding peptidyl-prolyl cis-trans isomerase activity phosphoprotein binding tau protein binding | Mus musculus | Acetylation Chaperone Cytoplasm Cytoskeleton Direct protein sequencing Isomerase Isopeptide bond Methylation Microtubule Mitochondrion Nucleus Phosphoprotein Reference proteome Repeat Rotamase TPR repeat Ubl conjugation | MTAEEMKAAE | MTAEEMKAAENGAQSAPLPLEGVDISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYGAAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIRTRGEGYARPNDGAMVEVALEGYHKDRLFDQRELCFEVGEGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGSVGKERFQIPPHAELRYEVRLKSFEKAKESWEMSSAEKLEQSNIVKERGTAYFKEGKYKQALLQYKKIVSWLEYESSFSGEEMQKVHALRLA... | androgen receptor signaling pathway chaperone-mediated protein folding copper ion transport embryo implantation male sex differentiation negative regulation of microtubule polymerization negative regulation of microtubule polymerization or depolymerization negative regulation of neuron projection development prostate g... |
cellular ketone metabolic process in utero embryonic development N-terminal peptidyl-glycine N-myristoylation protein localization to membrane regulation of rhodopsin mediated signaling pathway | cytoplasm; cytosol; plasma membrane | glycylpeptide N-tetradecanoyltransferase activity myristoyltransferase activity peptidyl-lysine N6-myristoyltransferase activity | Homo sapiens | 3D-structure Acyltransferase Alternative splicing Cytoplasm Membrane Phosphoprotein Reference proteome Transferase | MADESETAVK | MADESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKKQKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTM... | cellular ketone metabolic process in utero embryonic development N-terminal peptidyl-glycine N-myristoylation protein localization to membrane regulation of rhodopsin mediated signaling pathway cytoplasm; cytosol; plasma membrane glycylpeptide N-tetradecanoyltransferase activity myristoyltransferase activity peptidyl-l... |
actin filament depolymerization activation of cysteine-type endopeptidase activity activation of cysteine-type endopeptidase activity involved in apoptotic process apoptotic process apoptotic process involved in development defense response to Gram-negative bacterium embryo development ending in birth or egg hatching e... | caspase complex; cytosol; membrane; mitochondrion; nucleus; perinuclear region of cytoplasm; protein-containing complex | ADP binding ATP binding BH1 domain binding BH3 domain binding caspase binding cysteine-type endopeptidase activator activity involved in apoptotic process endopeptidase activator activity identical protein binding magnesium ion binding peptidase activator activity involved in apoptotic process | Caenorhabditis elegans | 3D-structure Alternative splicing Apoptosis ATP-binding Cytoplasm Magnesium Metal-binding Mitochondrion Nucleotide-binding Reference proteome | MLCEIECRAL | MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLARVVSDTDDSHSITDFINRVLSRSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDEC... | actin filament depolymerization activation of cysteine-type endopeptidase activity activation of cysteine-type endopeptidase activity involved in apoptotic process apoptotic process apoptotic process involved in development defense response to Gram-negative bacterium embryo development ending in birth or egg hatching e... |
apoptotic process proteolysis | extracellular region | metal ion binding metalloendopeptidase activity toxin activity | Bothrops jararaca | Apoptosis Calcium Cell adhesion impairing toxin Direct protein sequencing Disulfide bond Fibrinogenolytic toxin Glycoprotein Hemorrhagic toxin Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Platelet aggregation activating toxin Platelet aggregation inhibiting toxin Protease Pyrrolidone carboxylic ac... | ATRPKGAVQP | ATRPKGAVQPKYEDAMQYEFKVNGEPVVLHLEKNKGLFSKDYSEIHYSPDGREITTYPPVEDHCYYHGRIENDADSTASISACNGLKGYFKLQRETYFIEPLKLPDSEAHAVFKYENVEKEDEAPKMCGVTQNWKSYEPIKKASQLAFTAEQQRYDPYKYIEFFVVVDQGTVTKNNGDLDKIKARMYELANIVNEIFRYLYMHVALVGLEIWSNGDKITVKPDVDYTLNSFAEWRKTDLLTRKKHDNAQLLTAIDFNGPTIGYAYIGSMCHPKRSVGIVQDYSPINLVVAVIMAHEMGHNLGIHHDTGSCSCGDYPCIMG... | apoptotic process proteolysis extracellular region metal ion binding metalloendopeptidase activity toxin activity Bothrops jararaca Apoptosis Calcium Cell adhesion impairing toxin Direct protein sequencing Disulfide bond Fibrinogenolytic toxin Glycoprotein Hemorrhagic toxin Hemostasis impairing toxin Hydrolase Metal-b... |
microtubule-based process | cytoplasm; microtubule | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Oncorhynchus keta | Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding | MREVISMHVG | MREVISMHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTCGGGDDSFNTFFSETGAGKHVPRAIFVDLEPTVIDEVRTGIYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDIVLDRTRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPSYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVADITNACFEPANQMVKCDPRHGKYMACCLLYR... | microtubule-based process cytoplasm; microtubule GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton Oncorhynchus keta Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding MREVISMHVG MREVISMHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKT... |
progesterone metabolic process steroid biosynthetic process | membrane | 17-alpha-hydroxyprogesterone aldolase activity heme binding iron ion binding steroid 17-alpha-monooxygenase activity | Oncorhynchus mykiss | Heme Iron Lipid metabolism Lyase Membrane Metal-binding Monooxygenase Oxidoreductase Steroidogenesis | MAWFLCMCVF | MAWFLCMCVFSVVGLGLLLLQVKLRRSLETRGGPPSLPVFPLIGSLLSLRSNQAPHVLFQKLQQKYGHTYSLMMGPHTVILVNHHQHAKEVLLKKGKIFAGRPRTVTTDLLTRDGKDIAFADYGATWRFHRKTVHGALCMFGEGSASIEKIICREALSLCDTLRESGSASLDLSPELTRAVTNVVCSLCFSSSYCRGDPEFEAMLQFSQGIVDTVAKDSLVDIFPWLQVFPNADLRLLKQCVSIRDKLLQKKYEEHKSDYSDHEQRDLLDALLRAKRSAENNNTAEITMETVGLSEDHLLMTVGDIFGAGVETTSTVLKW... | progesterone metabolic process steroid biosynthetic process membrane 17-alpha-hydroxyprogesterone aldolase activity heme binding iron ion binding steroid 17-alpha-monooxygenase activity Oncorhynchus mykiss Heme Iron Lipid metabolism Lyase Membrane Metal-binding Monooxygenase Oxidoreductase Steroidogenesis MAWFLCMCVF M... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib antigen processing and presentation of exogenous peptide antigen via MHC class Ib immune response negative regulation of na... | cell surface; early endosome membrane; endoplasmic reticulum; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; Golgi membrane; lumenal side of endoplasmic reticulum membrane; lysosomal membrane; membrane; MHC class I protein complex; MHC class Ib protein complex; phagocytic... | 14-3-3 protein binding beta-2-microglobulin binding peptide antigen binding signaling receptor binding TAP1 binding TAP2 binding | Homo sapiens | 3D-structure Alternative splicing Cell membrane Disulfide bond Endosome Glycoprotein Immunity Lysosome Membrane MHC I Reference proteome Signal Transmembrane Transmembrane helix | MAPRSLLLLL | MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVT... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib antigen processing and presentation of exogenous peptide antigen via MHC class Ib immune response negative regulation of na... |
activation of adenylate cyclase activity adenylate cyclase-modulating G protein-coupled receptor signaling pathway cellular response to hormone stimulus G protein-coupled receptor signaling pathway hemostasis negative regulation of cell population proliferation positive regulation of cell population proliferation posit... | clathrin-coated endocytic vesicle membrane; endocytic vesicle; endoplasmic reticulum; endosome; Golgi apparatus; membrane; perinuclear region of cytoplasm; plasma membrane | peptide binding vasopressin receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Diabetes insipidus Disease variant G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MLMASTTSAV | MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCT... | activation of adenylate cyclase activity adenylate cyclase-modulating G protein-coupled receptor signaling pathway cellular response to hormone stimulus G protein-coupled receptor signaling pathway hemostasis negative regulation of cell population proliferation positive regulation of cell population proliferation posit... |
heme catabolic process heme oxidation response to hypoxia response to oxidative stress | endoplasmic reticulum membrane; membrane; plasma membrane; specific granule membrane | heme binding heme oxygenase (decyclizing) activity metal ion binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Direct protein sequencing Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Oxidoreductase Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix | MSAEVETSEG | MSAEVETSEGVDESEKKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQAGSTLARETLEDGFPVHDGKGDMRKCPFYAAEQDKGALEGSSCPFRTAMAVLRKPSLQFILAAGVALAAGLLAWYYM | heme catabolic process heme oxidation response to hypoxia response to oxidative stress endoplasmic reticulum membrane; membrane; plasma membrane; specific granule membrane heme binding heme oxygenase (decyclizing) activity metal ion binding Homo sapiens 3D-structure Acetylation Alternative splicing Direct protein seque... |
de novo' AMP biosynthetic process AMP biosynthetic process aspartate metabolic process cellular response to electrical stimulus immune system process IMP metabolic process response to ammonium ion response to purine-containing compound | cytoplasm; cytosol; extracellular exosome; mitochondrion | adenylosuccinate synthase activity GTP binding magnesium ion binding phosphate ion binding | Homo sapiens | 3D-structure Cytoplasm GTP-binding Ligase Magnesium Metal-binding Mitochondrion Nucleotide-binding Purine biosynthesis Reference proteome | MAFAETYPAA | MAFAETYPAASSLPNGDCGRPRARPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLEGWEKRLIISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFDGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGEL... | de novo' AMP biosynthetic process AMP biosynthetic process aspartate metabolic process cellular response to electrical stimulus immune system process IMP metabolic process response to ammonium ion response to purine-containing compound cytoplasm; cytosol; extracellular exosome; mitochondrion adenylosuccinate synthase a... |
glycogen biosynthetic process starch biosynthetic process | amyloplast; chloroplast | ATP binding glucose-1-phosphate adenylyltransferase activity | Triticum aestivum | Allosteric enzyme Amyloplast ATP-binding Chloroplast Nucleotide-binding Nucleotidyltransferase Plastid Reference proteome Starch biosynthesis Transferase Transit peptide | MDVPLASKTF | MDVPLASKTFPSPSPSKREQCNIDGHKSSSKHADLNPHVDDSVLGIILGGGAGTRLYPLTKKRAKPAVPLGANYRLIDIPVSNCLNSNISKIYVRTQFNSASLNRHLSRAYGSNIGGYKNEGFVEVLAAQQSPDNPDWFQGTADAVRQYLWLFEEHNVMEYLILAGDHLYRMDYEKFIQAHRETDADITVAALPMDEERATAFGLMKIDEEGRIIEFAEKPKGEQLKAMMVDTTILGLDDARAKEMPYIASMGIYVISKHVMLQLLREQFPGANDFGSEVIPGATSTGMRVQAYLYDGYWEDIGTIEAFYNANLGITKKP... | glycogen biosynthetic process starch biosynthetic process amyloplast; chloroplast ATP binding glucose-1-phosphate adenylyltransferase activity Triticum aestivum Allosteric enzyme Amyloplast ATP-binding Chloroplast Nucleotide-binding Nucleotidyltransferase Plastid Reference proteome Starch biosynthesis Transferase Trans... |
glycogen biosynthetic process starch biosynthetic process | amyloplast; chloroplast | ATP binding glucose-1-phosphate adenylyltransferase activity | Hordeum vulgare | Allosteric enzyme Amyloplast ATP-binding Chloroplast Nucleotide-binding Nucleotidyltransferase Plastid Starch biosynthesis Transferase Transit peptide | MSSMQFSSVL | MSSMQFSSVLPLEGKACVSPVRREGSACERLKIGDSSSIRHERASRRMCNGGARGPAATGAQCVLTSDASPADTLVLRTSFRRNYADPNEVAAVILGGGTGTQLFPLTSTRATPAVPIGGCYRLIDIPMSNCFNSGINKIFVMTQFNSASLNRHIHRTYLGGGINFTDGSVEVLAATQMPGEAAGWFRGTADAVRKFIWVLEDYYKHKSIEHILILSGDQLYRMDYMELVQKHVDDNADITLSCAPVGESRASEYGLVKFDSSGRVIQFSEKPKGDDLEAMKVDTSFLNFAIDDPAKYPYIASMGVYVFKRDVLLNLLKS... | glycogen biosynthetic process starch biosynthetic process amyloplast; chloroplast ATP binding glucose-1-phosphate adenylyltransferase activity Hordeum vulgare Allosteric enzyme Amyloplast ATP-binding Chloroplast Nucleotide-binding Nucleotidyltransferase Plastid Starch biosynthesis Transferase Transit peptide MSSMQFSSVL... |
associative learning chemical synaptic transmission chloride transmembrane transport gamma-aminobutyric acid import gamma-aminobutyric acid reuptake inorganic anion import across plasma membrane memory negative regulation of synaptic transmission, GABAergic positive regulation of gamma-aminobutyric acid secretion respo... | axon; cell surface; GABA-ergic synapse; membrane; neuronal cell body; plasma membrane; postsynaptic membrane; presynaptic membrane | gamma-aminobutyric acid transmembrane transporter activity gamma-aminobutyric acid:sodium:chloride symporter activity identical protein binding metal ion binding sodium:chloride symporter activity | Homo sapiens | 3D-structure Cell membrane Cell projection Disease variant Disulfide bond Epilepsy Glycoprotein Membrane Metal-binding Neurotransmitter transport Phosphoprotein Reference proteome Sodium Symport Synapse Transmembrane Transmembrane helix Transport | MATNGSKVAD | MATNGSKVADGQISTEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSMVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDS... | associative learning chemical synaptic transmission chloride transmembrane transport gamma-aminobutyric acid import gamma-aminobutyric acid reuptake inorganic anion import across plasma membrane memory negative regulation of synaptic transmission, GABAergic positive regulation of gamma-aminobutyric acid secretion respo... |
behavioral response to nicotine chemical synaptic transmission presynaptic modulation of chemical synaptic transmission response to nicotine signal transduction synaptic transmission, cholinergic | acetylcholine-gated channel complex; dopaminergic synapse; neuron projection; plasma membrane; postsynaptic membrane; presynapse; synapse | acetylcholine receptor activity acetylcholine-gated monoatomic cation-selective channel activity ligand-gated monoatomic ion channel activity | Homo sapiens | Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MAARGSGPRA | MAARGSGPRALRLLLLVQLVAGRCGLAGAAGGAQRGLSEPSSIAKHEDSLLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSATGSKGNRTDSCCWYPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFYLPSNEGEKICLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFT... | behavioral response to nicotine chemical synaptic transmission presynaptic modulation of chemical synaptic transmission response to nicotine signal transduction synaptic transmission, cholinergic acetylcholine-gated channel complex; dopaminergic synapse; neuron projection; plasma membrane; postsynaptic membrane; presyn... |
amyloid-beta clearance by transcytosis extracellular negative regulation of signal transduction negative regulation of amyloid-beta clearance negative regulation of protein binding negative regulation of receptor internalization negative regulation of very-low-density lipoprotein particle clearance positive regulation ... | cell surface; cis-Golgi network; endomembrane system; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; endosome; endosome lumen; extracellular region; Golgi apparatus; Golgi lumen; plasma membrane; rough endoplasmic reticulum lumen | amyloid-beta binding heparin binding lipase binding low-density lipoprotein particle receptor binding receptor antagonist activity receptor ligand activity signaling receptor binding very-low-density lipoprotein particle receptor binding | Homo sapiens | 3D-structure Coiled coil Direct protein sequencing Endoplasmic reticulum Endosome Glycoprotein Golgi apparatus Heparin-binding Phosphoprotein Reference proteome Signal | MAPRRVRSFL | MAPRRVRSFLRGLPALLLLLLFLGPWPAASHGGKYSREKNQPKPSPKRESGEEFRMEKLNQLWEKAQRLHLPPVRLAELHADLKIQERDELAWKKLKLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGERVSRS... | amyloid-beta clearance by transcytosis extracellular negative regulation of signal transduction negative regulation of amyloid-beta clearance negative regulation of protein binding negative regulation of receptor internalization negative regulation of very-low-density lipoprotein particle clearance positive regulation ... |
adenylate cyclase-activating adrenergic receptor signaling pathway adrenergic receptor signaling pathway angiogenesis female pregnancy G protein-coupled receptor signaling pathway MAPK cascade platelet activation positive regulation of blood pressure positive regulation of MAPK cascade positive regulation of neuron dif... | cell surface; cytosol; intracellular membrane-bounded organelle; plasma membrane | adrenergic receptor activity alpha2-adrenergic receptor activity epinephrine binding | Mus musculus | Cell membrane Disulfide bond G-protein coupled receptor Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MSGPAMVHQE | MSGPAMVHQEPYSVQATAAIASAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFWRAWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQRPEPHGLPQCELNQEAWYILASSIGSFFAPCLIMILVYLRIYVIAKRSHCRGLGAKRGSGEGESKKPHPAAGGVPASAKVPTLVSPLSSVGEANGHPKPPREKEEGETPEDPEARALPPNWSALPRSVQDQKKGTSGATAEKGAEEDEEEVEECEPQTLPA... | adenylate cyclase-activating adrenergic receptor signaling pathway adrenergic receptor signaling pathway angiogenesis female pregnancy G protein-coupled receptor signaling pathway MAPK cascade platelet activation positive regulation of blood pressure positive regulation of MAPK cascade positive regulation of neuron dif... |
cellular response to histamine chemical synaptic transmission G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger positive regulation of vasoconstriction regulation of vascular permeability | dendrite; plasma membrane; synapse | G protein-coupled serotonin receptor activity histamine receptor activity neurotransmitter receptor activity | Bos taurus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MTCPNSSCVF | MTCPNSSCVFEDKMCQGNKTAPANDAQLTPLVVVLSTISLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGVVVMPMNILYLLMSRWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLKYLRYRTKTRASITILAAWFLSFLWIIPILGWRHFQPKTPEPREDKCETDFYNVTWFKVMTAIINFYLPTLLMLWFYAKIYKAVRQHCQHRELINGSFPSFSDMKMKPENLQVGAKKPGKESPWEVLKRKPKDTGGGPVLKPPSQEPKEVTSPGVFSQEKEEKDGELGKFYCFPLDTVQAQPEAEG... | cellular response to histamine chemical synaptic transmission G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger positive regulation of vasoconstriction regulation of vascular permeability dendrite; plasma membrane; synapse G protein-... |
intestine smooth muscle contraction negative regulation of luteinizing hormone secretion operant conditioning positive regulation of acetylcholine secretion, neurotransmission positive regulation of flagellated sperm motility positive regulation of monoatomic ion transport positive regulation of uterine smooth muscle c... | plasma membrane; sperm flagellum; sperm head; sperm midpiece | substance K receptor activity | Mus musculus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MGAHASVTDT | MGAHASVTDTNILSGLESNATGVTAFSMPGWQLALWATAYLALVLVAVTGNATVIWIILAHERMRTVTNYFIINLALADLCMAAFNATFNFIYASHNIWYFGSTFCYFQNLFPVTAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAVIWLVALALASPQCFYSTITVDQGATKCVVAWPNDNGGKMLLLYHLVVFVLIYFLPLVVMFAAYSVIGLTLWKRAVPRHQAHGANLRHLQAKKKFVKAMVLVVVTFAICWLPYHLYFILGTFQEDIYYRKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRL... | intestine smooth muscle contraction negative regulation of luteinizing hormone secretion operant conditioning positive regulation of acetylcholine secretion, neurotransmission positive regulation of flagellated sperm motility positive regulation of monoatomic ion transport positive regulation of uterine smooth muscle c... |
G protein-coupled receptor signaling pathway learning or memory motor behavior phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of behavioral fear response positive regulation of respiratory gaseous exchange psychomotor behavior regulation of cell population proliferation resp... | plasma membrane | G protein-coupled peptide receptor activity neuropeptide binding neuropeptide receptor activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MALNDCFLLN | MALNDCFLLNLEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPF... | G protein-coupled receptor signaling pathway learning or memory motor behavior phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of behavioral fear response positive regulation of respiratory gaseous exchange psychomotor behavior regulation of cell population proliferation resp... |
animal organ regeneration axonogenesis cellular response to hormone stimulus cholecystokinin signaling pathway eating behavior feeding behavior forebrain development G protein-coupled receptor signaling pathway gastric acid secretion insulin secretion neuron migration pancreas development positive regulation of cytosol... | endosome; membrane; plasma membrane; terminal bouton | cholecystokinin receptor activity peptide binding peptide hormone binding | Rattus norvegicus | Cell membrane Direct protein sequencing Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MSHSPARQHL | MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAAN... | animal organ regeneration axonogenesis cellular response to hormone stimulus cholecystokinin signaling pathway eating behavior feeding behavior forebrain development G protein-coupled receptor signaling pathway gastric acid secretion insulin secretion neuron migration pancreas development positive regulation of cytosol... |
behavioral defense response cholecystokinin signaling pathway digestive tract development ERK1 and ERK2 cascade estrous cycle gastric acid secretion gland development histamine secretion pH reduction phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of behavioral fear response ... | membrane; plasma membrane | cholecystokinin receptor activity gastrin receptor activity peptide hormone binding type B gastrin/cholecystokinin receptor binding | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MELLKLNRSV | MELLKLNRSVQGPGPGSGSSLCRPGVSLLNSSSAGNLSCDPPRIRGTGTRELEMAIRITLYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAISYLMGVSVSVSTLNLVAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTMVQPVGPRVLQCMHRWPSARVQQTWSVLLLLLLFFIPGVVIAVAYGLISRELYLGLHFDGENDSETQSRARNQGGLPGGAAPGPVHQNGGCRPVTSVAGEDSDGCCVQLPRSRLEMTTLTTPTPGPV... | behavioral defense response cholecystokinin signaling pathway digestive tract development ERK1 and ERK2 cascade estrous cycle gastric acid secretion gland development histamine secretion pH reduction phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of behavioral fear response ... |
G protein-coupled receptor signaling pathway hippocampus development male gonad development negative regulation of protein phosphorylation positive regulation of canonical NF-kappaB signal transduction positive regulation of cell population proliferation positive regulation of DNA replication positive regulation of ino... | cell surface; plasma membrane | angiotensin receptor activity G protein-coupled receptor activity peptide binding | Mus musculus | Cell membrane G-protein coupled receptor Glycoprotein Membrane Proto-oncogene Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MDQSNMTSLA | MDQSNMTSLAEEKAMNTSSRNASLGSSHPPIPIVHWVIMSISPLGFVENGILLWFLCFRMRRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHHYTIVTLSVTFLFGYNTGLYLLTAISVERCLSVLYPIWYRCHRPKHQSAFVCALLWALSCLVTTMEYVMCIDSGEESHSRSDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIFAMPMRVLYLLYYEYWSAFGNLHNISLLFSTINSSANPFIYFFVGSSKKKRFRESLKVVLTRAFKDEMQPRRQEGNGNTVSI... | G protein-coupled receptor signaling pathway hippocampus development male gonad development negative regulation of protein phosphorylation positive regulation of canonical NF-kappaB signal transduction positive regulation of cell population proliferation positive regulation of DNA replication positive regulation of ino... |
calcium-mediated signaling cell chemotaxis G protein-coupled receptor signaling pathway inflammatory response kidney development maintenance of blood vessel diameter homeostasis by renin-angiotensin positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis positive regulation... | plasma membrane | angiotensin type I receptor activity angiotensin type II receptor activity bradykinin receptor binding protein heterodimerization activity | Sus scrofa | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MILNSSTEDS | MILNSSTEDSIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVCAFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIHDCKIADIVDTAMPITICLAYFNNCLNPLFYGFLGKKFKKYFLQLLKYI... | calcium-mediated signaling cell chemotaxis G protein-coupled receptor signaling pathway inflammatory response kidney development maintenance of blood vessel diameter homeostasis by renin-angiotensin positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis positive regulation... |
de novo' AMP biosynthetic process 'de novo' IMP biosynthetic process 'de novo' XMP biosynthetic process aerobic respiration AMP biosynthetic process AMP salvage GMP biosynthetic process purine nucleotide biosynthetic process response to hypoxia response to muscle activity response to nutrient response to starvation | cytosol; protein-containing complex | (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity identical protein binding N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Direct protein sequencing Disease variant Epilepsy Isopeptide bond Lyase Purine biosynthesis Reference proteome Ubl conjugation | MAAGGDHGSP | MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQ... | de novo' AMP biosynthetic process 'de novo' IMP biosynthetic process 'de novo' XMP biosynthetic process aerobic respiration AMP biosynthetic process AMP salvage GMP biosynthetic process purine nucleotide biosynthetic process response to hypoxia response to muscle activity response to nutrient response to starvation cyt... |
hydrogen peroxide catabolic process response to hydrogen peroxide seed germination | cytoplasm; glyoxysome; nucleus | catalase activity heme binding metal ion binding | Gossypium hirsutum | Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Peroxisome Reference proteome | MDPYKFRPSS | MDPYKFRPSSSFDSPFWTTNSGAPVWNNNSSLTVGARGPILLEDYHLVEKLANFDRERIPERVVHARGASAKGFFEVTHDISQLTCADFLRAPGVQTPLIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNFDLVGNNFPVFFIRDGMKFPDMVHALKPNPKSHIQENWRILDFFSHHPESLHMFTFLFDDIGVPQDYRHMDGSGVHTYTLINKAGKSHYVKFHWKPTCGVKSLLEDEAIRVGGANHSHATQDLYDSIAAGNYPEWKLFIQIMDPLHEDRFDFDPLDVTKTWPEDIFPLQPMGRMVLNKNIDNFFAENE... | hydrogen peroxide catabolic process response to hydrogen peroxide seed germination cytoplasm; glyoxysome; nucleus catalase activity heme binding metal ion binding Gossypium hirsutum Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Peroxisome Reference proteome MDPYKFRPSS MDPYKFRPSSSFDSPFWTTNSGAPVWNN... |
entry into host fibrinolysis filamentous growth filamentous growth of a population of unicellular organisms in response to biotic stimulus fungal-type cell wall organization or biogenesis gluconeogenesis glycolytic process induction by symbiont of host defense response | cell surface; cytosol; external side of plasma membrane; extracellular region; extracellular vesicle; fungal biofilm matrix; fungal-type cell wall; hyphal cell wall; membrane; nucleus; phosphopyruvate hydratase complex; plasma membrane; yeast-form cell wall | high molecular weight kininogen binding magnesium ion binding phosphopyruvate hydratase activity protein-glutamine gamma-glutamyltransferase activity | Candida albicans | 3D-structure Cytoplasm Glycolysis Lyase Magnesium Metal-binding Reference proteome | MSYATKIHAR | MSYATKIHARYVYDSRGNPTVEVDFTTDKGLFRSIVPSGASTGVHEALELRDGDKSKWLGKGVLKAVANVNDIIAPALIKAKIDVVDQAKIDEFLLSLDGTPNKSKLGANAILGVSLAAANAAAAAQGIPLYKHIANISNAKKGKFVLPVPFQNVLNGGSHAGGALAFQEFMIAPTGVSTFSEALRIGSEVYHNLKSLTKKKYGQSAGNVGDEGGVAPDIKTPKEALDLIMDAIDKAGYKGKVGIAMDVASSEFYKDGKYDLDFKNPESDPSKWLSGPQLADLYEQLISEYPIVSIEDPFAEDDWDAWVHFFERVGDKIQ... | entry into host fibrinolysis filamentous growth filamentous growth of a population of unicellular organisms in response to biotic stimulus fungal-type cell wall organization or biogenesis gluconeogenesis glycolytic process induction by symbiont of host defense response cell surface; cytosol; external side of plasma mem... |
cell septum assembly cell wall chitin biosynthetic process conidium formation division septum site selection fungal-type cell wall organization hyphal growth | cell periphery; cell septum; hyphal tip; plasma membrane | chitin synthase activity | Emericella nidulans | Cell membrane Cell wall biogenesis/degradation Glycosyltransferase Membrane Reference proteome Transferase Transmembrane Transmembrane helix | MSYNRLGDPY | MSYNRLGDPYGDDRDARSPIMNPSSLSNRSPSPGRPLDGYQLSDAPYGHHHHIEMPSSDRLAEQPTYSVERIPQSYGHNEAYEAQHQHYPGYEYSVDPEAHHDAYYTQPYQPTVTPGHDDYDLGQYPGHQHSYQDDEPILQPEDPFQAQNPYSDDYQEDMTIAPTPSPAPLRRWKTVKEVQLFQGNLVLDCPIAPKLLNQIPHAENGQRDEFTHMRYSAATCDPKDFFEERFTLRQKLFAKPRHTELFIVVTMYNEDDFLFARTMVGVFKNIEHMCSRTRSKTWGKDAWKKIVVCVISDGRAKINPRTRAVLAGLGCYQD... | cell septum assembly cell wall chitin biosynthetic process conidium formation division septum site selection fungal-type cell wall organization hyphal growth cell periphery; cell septum; hyphal tip; plasma membrane chitin synthase activity Emericella nidulans Cell membrane Cell wall biogenesis/degradation Glycosyltran... |
myo-inositol import across plasma membrane myo-inositol transport pseudohyphal growth transmembrane transport | cell periphery; fungal-type vacuole; fungal-type vacuole membrane; membrane; plasma membrane | myo-inositol transmembrane transporter activity myo-inositol:proton symporter activity | Saccharomyces cerevisiae | Cell membrane Glycoprotein Isopeptide bond Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport Ubl conjugation | MGIHIPYLTS | MGIHIPYLTSKTSQSNVGDAVGNADSVEFNSEHDSPSKRGKITLESHEIQRAPASDDEDRIQIKPVNDEDDTSVMITFNQSLSPFIITLTFVASISGFMFGYDTGYISSALISIGTDLDHKVLTYGEKEIVTAATSLGALITSIFAGTAADIFGRKRCLMGSNLMFVIGAILQVSAHTFWQMAVGRLIMGFGVGIGSLIAPLFISEIAPKMIRGRLTVINSLWLTGGQLVAYGCGAGLNYVNNGWRILVGLSLIPTAVQFTCLCFLPDTPRYYVMKGDLARATEVLKRSYTDTSEEIIERKVEELVTLNQSIPGKNVPEK... | myo-inositol import across plasma membrane myo-inositol transport pseudohyphal growth transmembrane transport cell periphery; fungal-type vacuole; fungal-type vacuole membrane; membrane; plasma membrane myo-inositol transmembrane transporter activity myo-inositol:proton symporter activity Saccharomyces cerevisiae Cell... |
cellular response to epinephrine stimulus cellular response to insulin stimulus glycolytic process phosphorylation pyruvate biosynthetic process response to ATP response to cAMP response to glucose response to hypoxia response to metal ion response to nutrient | cytoplasm; cytosol; extracellular exosome; pyruvate kinase complex | ATP binding kinase activity magnesium ion binding monosaccharide binding potassium ion binding pyruvate kinase activity | Homo sapiens | 3D-structure Allosteric enzyme Alternative splicing ATP-binding Disease variant Glycolysis Hereditary hemolytic anemia Kinase Magnesium Manganese Metal-binding Nucleotide-binding Phosphoprotein Potassium Pyruvate Reference proteome Transferase | MSIQENISSL | MSIQENISSLQLRSWVSKSQRDLAKSILIGAPGGPAGYLRRASVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGV... | cellular response to epinephrine stimulus cellular response to insulin stimulus glycolytic process phosphorylation pyruvate biosynthetic process response to ATP response to cAMP response to glucose response to hypoxia response to metal ion response to nutrient cytoplasm; cytosol; extracellular exosome; pyruvate kinase ... |
defense response regulation of defense response to virus response to virus | extracellular region | mannose binding | Galanthus nivalis | 3D-structure Antiviral protein Direct protein sequencing Disulfide bond Lectin Mannose-binding Plant defense Secreted Signal | MAKASLLILA | MAKASLLILAAIFLGVITPSCLSDNILYSGETLSTGEFLNYGSFVFIMQEDCNLVLYDVDKPIWATNTGGLSRSCFLSMQTDGNLVVYNPSNKPIWASNTGGQNGNYVCILQKDRNVVIYGTDRWATGTHTGLVGIPASPPSEKYPTAGKIKLVTAK | defense response regulation of defense response to virus response to virus extracellular region mannose binding Galanthus nivalis 3D-structure Antiviral protein Direct protein sequencing Disulfide bond Lectin Mannose-binding Plant defense Secreted Signal MAKASLLILA MAKASLLILAAIFLGVITPSCLSDNILYSGETLSTGEFLNYGSFVFIMQEDCNL... |
exocytosis intracellular protein transport positive regulation of vesicle fusion vesicle docking involved in exocytosis vesicle-mediated transport | cell periphery; cellular bud neck; cellular bud tip; plasma membrane | SNARE binding syntaxin binding | Saccharomyces cerevisiae | Protein transport Reference proteome Transport | MSDLIELQRN | MSDLIELQRNYLIGVLNQIETKNNLKFLIIDKTVETILSYLFLTPQELLNNVTSVDLIDSPTRKGQSSIEAIYILEPTKYNINCIDADFMVRPPKYRRCHIRFLPGLTNPIFQFFQSKRYIAQNLESFKPIELGFFVKESQFFETLQMEHSLQVFFNNNCKALIPTNVRKIVGSLVSLCVITGEYPIVRYSVSNPVEEEDARNGNAVVNANSLTRSIANAFQIAIDTYARNNPDFPPQNTERPRSILIITDRTLDPFAPILHDFSYQAMAYDLVANVDTQKDIYHYSAENEAGEQEEKVSKLVDLYDPDWIDLKHQHIMD... | exocytosis intracellular protein transport positive regulation of vesicle fusion vesicle docking involved in exocytosis vesicle-mediated transport cell periphery; cellular bud neck; cellular bud tip; plasma membrane SNARE binding syntaxin binding Saccharomyces cerevisiae Protein transport Reference proteome Transport ... |
DNA repair double-strand break repair via nonhomologous end joining interstrand cross-link repair | nucleus | 5'-3' DNA exonuclease activity 5'-3' exonuclease activity damaged DNA binding metal ion binding | Saccharomyces cerevisiae | DNA damage DNA repair Exonuclease Hydrolase Magnesium Metal-binding Nuclease Nucleus Reference proteome Zinc Zinc-finger | MSRKSIVQIR | MSRKSIVQIRRSEVKRKRSSTASSTSEGKTLHKNTHTSSKRQRTLTEFNIPTSSNLPVRSSSYSFSRFSCSTSNKNTEPVIINDDDHNSICLEDTAKVEITIDTDEEELVSLHDNEVSAIENRTEDRIVTELEEQVNVKVSTEVIQCPICLENLSHLELYERETHCDTCIGSDPSNMGTPKKNIRSFISNPSSPAKTKRDIATSKKPTRVKLVLPSFKIIKFNNGHEIVVDGFNYKASETISQYFLSHFHSDHYIGLKKSWNNPDENPIKKTLYCSKITAILVNLKFKIPMDEIQILPMNKRFWITDTISVVTLDANHCP... | DNA repair double-strand break repair via nonhomologous end joining interstrand cross-link repair nucleus 5'-3' DNA exonuclease activity 5'-3' exonuclease activity damaged DNA binding metal ion binding Saccharomyces cerevisiae DNA damage DNA repair Exonuclease Hydrolase Magnesium Metal-binding Nuclease Nucleus Referen... |
long-chain fatty acid import into cell long-chain fatty acid metabolic process long-chain fatty-acyl-CoA metabolic process sphingoid long-chain base transport | endoplasmic reticulum; lipid droplet; mitochondrial outer membrane; mitochondrion; plasma membrane | ATP binding long-chain fatty acid-CoA ligase activity medium-chain fatty acid-CoA ligase activity | Saccharomyces cerevisiae | ATP-binding Cell membrane Direct protein sequencing Fatty acid metabolism Isopeptide bond Ligase Lipid droplet Lipid metabolism Magnesium Membrane Nucleotide-binding Reference proteome Ubl conjugation | MVAQYTVPVG | MVAQYTVPVGKAANEHETAPRRNYQCREKPLVRPPNTKCSTVYEFVLECFQKNKNSNAMGWRDVKEIHEESKSVMKKVDGKETSVEKKWMYYELSHYHYNSFDQLTDIMHEIGRGLVKIGLKPNDDDKLHLYAATSHKWMKMFLGAQSQGIPVVTAYDTLGEKGLIHSLVQTGSKAIFTDNSLLPSLIKPVQAAQDVKYIIHFDSISSEDRRQSGKIYQSAHDAINRIKEVRPDIKTFSFDDILKLGKESCNEIDVHPPGKDDLCCIMYTSGSTGEPKGVVLKHSNVVAGVGGASLNVLKFVGNTDRVICFLPLAHIFEL... | long-chain fatty acid import into cell long-chain fatty acid metabolic process long-chain fatty-acyl-CoA metabolic process sphingoid long-chain base transport endoplasmic reticulum; lipid droplet; mitochondrial outer membrane; mitochondrion; plasma membrane ATP binding long-chain fatty acid-CoA ligase activity medium-c... |
medium-term memory negative regulation of oocyte maturation negative regulation of protein kinase C signaling positive regulation of gene expression regulation of establishment of cell polarity regulation of protein phosphorylation | cAMP-dependent protein kinase complex; cytosol; membrane | cAMP binding cAMP-dependent protein kinase regulator activity | Caenorhabditis elegans | Alternative splicing cAMP cAMP-binding Cytoplasm Disulfide bond Nucleotide-binding Phosphoprotein Reference proteome Repeat | MSGGNEEDQL | MSGGNEEDQLAQCQAYVQRHNIQQLVKEAIVVLCIHKPDNPVLFLKDHFEKLNEQRAQEGGNPDAADDDDIIVEPPKRSGGRRTGISAEPIKEDDTEYKKVVIPKDDATRRSLESAMRKNLLFAHLEEDEQKTMYDAMFPVEKSAGETIIEQGEEGDNFYVIDKGTVDVYVNHEYVLTINEGGSFGELALIYGTPRAATVIAKTDVKLWAIDRLTYRRILMGSVTKKRKMYDEFLSKVQILADLDQWERANVADALERCDFEPGTHVVEQGQPGDEFFIILEGEANVLQKRSDDAPFDVVGHLGMSDYFGEIALLLDRPR... | medium-term memory negative regulation of oocyte maturation negative regulation of protein kinase C signaling positive regulation of gene expression regulation of establishment of cell polarity regulation of protein phosphorylation cAMP-dependent protein kinase complex; cytosol; membrane cAMP binding cAMP-dependent pro... |
action potential calcium ion transport heart development intracellular sequestering of iron ion muscle organ development negative regulation of cardiac muscle contraction negative regulation of heart rate negative regulation of ryanodine-sensitive calcium-release channel activity positive regulation of insulin secretio... | cytoplasm; cytosol; endoplasmic reticulum membrane; extracellular exosome; membrane; nucleoplasm; sarcoplasmic reticulum; sarcoplasmic reticulum membrane; T-tubule; Z disc | calcium channel regulator activity calcium ion binding DNA-binding transcription factor binding identical protein binding protease binding protein heterodimerization activity signaling receptor binding transmembrane transporter binding | Homo sapiens | 3D-structure Alternative splicing Calcium Cytoplasm Direct protein sequencing Membrane Metal-binding Reference proteome Repeat Sarcoplasmic reticulum | MAYPGHPGAG | MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV | action potential calcium ion transport heart development intracellular sequestering of iron ion muscle organ development negative regulation of cardiac muscle contraction negative regulation of heart rate negative regulation of ryanodine-sensitive calcium-release channel activity positive regulation of insulin secretio... |
defense response to Gram-positive bacterium embryo development ending in birth or egg hatching locomotion negative regulation of locomotion nematode larval development positive regulation of neurotransmitter secretion positive regulation of programmed cell death proton motive force-driven ATP synthesis response to hypo... | membrane; plasma membrane; synapse; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V0 domain | ATPase binding proton-transporting ATPase activity, rotational mechanism | Caenorhabditis elegans | Alternative splicing Hydrogen ion transport Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport | MGDYVTPGEE | MGDYVTPGEEPPQPGIYRSEQMCLAQLYLQSDASYQCVAELGELGLVQFRDLNPDVSSFQRKYVNEVRRCDEMERKLRYLEREIKKDQIPMLDTGENPDAPLPREMIDLEATFEKLENELREVNKNEETLKKNFSELTELKHILRKTQTFFEEVDHDRWRILEGGSGRRGRSTEREETRPLIDIGDMDDDSAARMSAQAAMLRLGFVAGVIQRERLPAFERLLWRACRGNVFLRTSEIDDVLNDTVTGDPVNKCVFIIFFQGDHLKTKVKKICEGFRATLYPCPDTPQERREMSIGVMTRIEDLKTVLGQTQDHRHRVLV... | defense response to Gram-positive bacterium embryo development ending in birth or egg hatching locomotion negative regulation of locomotion nematode larval development positive regulation of neurotransmitter secretion positive regulation of programmed cell death proton motive force-driven ATP synthesis response to hypo... |
DNA-templated transcription embryo development ending in birth or egg hatching gonad development male gonad development negative regulation of vulval development nematode male tail tip morphogenesis regulation of cell cycle regulation of DNA-templated transcription regulation of neurogenesis regulation of transcription... | DRM complex; nucleoplasm | DNA binding | Caenorhabditis elegans | Alternative splicing Developmental protein Nucleus Reference proteome Repressor Transcription Transcription regulation | MSSAVRSPRK | MSSAVRSPRKKAASDTSDPDRTSSPYSLRETSKVPSRYRNEELYLSPSRSIKRTGSPKKSPAKRLNGGRDSPSVNSLTRNSSLTMLAKAALDYESSSCALEYIFQPKEERRPPRRALALSPPPAPSNDLLAKDLEMIEMHQNLVAGLDDLDNPANMTNEAVEHRDTQSFFNMFSTDQERSAMMKQFKTYKNQTSEDVSTFMRANIKKLYNLLRYKKARQWVMCEFFYSAIDEQIFKEENEFATIIRESFPNLKNWNLTRIEWRSIRKLLGKPRRCSKVFFEEERMYLEEKRMKIRSVYEGSYLNDPSIDLKDLPAKLPRP... | DNA-templated transcription embryo development ending in birth or egg hatching gonad development male gonad development negative regulation of vulval development nematode male tail tip morphogenesis regulation of cell cycle regulation of DNA-templated transcription regulation of neurogenesis regulation of transcription... |
detoxification of arsenic-containing substance positive regulation of insulin secretion post-translational protein targeting to endoplasmic reticulum membrane tail-anchored membrane protein insertion into ER membrane | axon; GET complex; neuronal cell body | ATP binding ATP hydrolysis activity metal ion binding | Caenorhabditis elegans | ATP-binding Cytoplasm Endoplasmic reticulum Hydrolase Metal-binding Nucleotide-binding Reference proteome Transport Zinc | MSDQLEASIK | MSDQLEASIKNILEQKTLKWIFVGGKGGVGKTTCSCSLAAQLSKVRERVLLISTDPAHNISDAFSQKFTKTPTLVEGFKNLFAMEIDSNPNGEGVEMGNIEEMLQNAAQNEGGSGGFSMGKDFLQSFAGGLPGIDEAMSFGEMIKLIDSLDFDVVVFDTAPTGHTLRLLQFPTLLEKVFTKILSLQGMFGPMMNQFGGMFGMGGGSMNEMIEKMTTTLESVKKMNAQFKDPNCTTFVCVCIAEFLSLYETERLIQELSKQGIDTHNIIVNQLLFPDTDANGTVSCRKCASRQAIQSKYLTDIDELYEDFHVVKLPLLEAE... | detoxification of arsenic-containing substance positive regulation of insulin secretion post-translational protein targeting to endoplasmic reticulum membrane tail-anchored membrane protein insertion into ER membrane axon; GET complex; neuronal cell body ATP binding ATP hydrolysis activity metal ion binding Caenorhabdi... |
cAMP-mediated signaling cGMP catabolic process cGMP-mediated signaling chemosensory behavior chemotaxis determination of adult lifespan negative regulation of cAMP-mediated signaling negative regulation of cGMP-mediated signaling phototransduction positive regulation of cGMP-mediated signaling positive regulation of eg... | cytosol; mitochondrial inner membrane; mitochondrial matrix; mitochondrial outer membrane; nucleus; perinuclear region of cytoplasm; synaptic membrane | 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity cGMP-stimulated cyclic-nucleotide phosphodiesterase activity metal ion binding protein homodimerization activity | Caenorhabditis elegans | Alternative splicing cGMP Hydrolase Metal-binding Reference proteome | MLELRRNSSP | MLELRRNSSPSSAHPSPQTNCQNSQRGDGLHHHHHEAASGSTCCGGMTVFTGANAAKSSNEPAGSASPTVWRKTSHPPLHFNNNETRNRNLQMQLKNRGTKDDWGASLRYDIEEPTSSGLLELLPDVPIVRKLSRPLVKMDDQDDACSVASNESDRTVLSPLVPMSIFDQFLCLTNNLSALISCIIAEAKKNTEAEDYAVFLHDEDNKQMVLFNNETMLMTGKKFDMGYGIVGKVASTMRTMNIRDVSRCPFFNEEIDEQFSIKARNLIAFPLIDSSCSLIGVIVLYNKENGFSRHDEKYIKRFSYFVANSIAHAILAKQ... | cAMP-mediated signaling cGMP catabolic process cGMP-mediated signaling chemosensory behavior chemotaxis determination of adult lifespan negative regulation of cAMP-mediated signaling negative regulation of cGMP-mediated signaling phototransduction positive regulation of cGMP-mediated signaling positive regulation of eg... |
proteasomal protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasome core complex assembly proteasome-mediated ubiquitin-dependent protein catabolic process | cytosol; nucleus; proteasome complex; proteasome core complex, beta-subunit complex | endopeptidase activity threonine-type endopeptidase activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing Hydrolase Nucleus Protease Proteasome Reference proteome Threonine protease Zymogen | MQAIADSFSV | MQAIADSFSVPNRLVKELQYDNEQNLESDFVTGASQFQRLAPSLTVPPIASPQQFLRAHTDDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG | proteasomal protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasome core complex assembly proteasome-mediated ubiquitin-dependent protein catabolic process cytosol; nucleus; proteasome complex; proteasome core complex, beta-subunit complex endopeptidase activity threonine-type e... |
chromatin organization development of primary sexual characteristics negative regulation of transcription by RNA polymerase II | euchromatin; heterochromatin; nuclear speck; nucleoplasm; nucleus; PcG protein complex; PRC1 complex | chromatin binding DNA binding methylated histone binding | Mus musculus | Chromatin regulator Chromosome DNA-binding Isopeptide bond Methylation Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation | MEELSSVGEQ | MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKHTVTSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEEDDSDLDSKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKAARRPVSLAKVLKTTRKDLGTSAAKLPPPLSAPVAGLAALKAHTKEACGGPSTMATPENLASLMKGMAGSPSRGGIWQSSIVHYMNRMSQSQVQAASRLALKAQATNKCGLGLDLKVRTQKGGELGGSPAGGKVPKAPGGGAAEQ... | chromatin organization development of primary sexual characteristics negative regulation of transcription by RNA polymerase II euchromatin; heterochromatin; nuclear speck; nucleoplasm; nucleus; PcG protein complex; PRC1 complex chromatin binding DNA binding methylated histone binding Mus musculus Chromatin regulator Ch... |
DNA replication initiation DNA unwinding involved in DNA replication premeiotic DNA replication regulation of DNA-templated DNA replication initiation | chromatin; CMG complex; MCM complex | ATP binding ATP hydrolysis activity chromatin binding DNA binding DNA helicase activity metal ion binding | Xenopus laevis | ATP-binding Cell cycle Chromosome DNA replication DNA-binding Helicase Hydrolase Metal-binding Nucleotide-binding Nucleus Reference proteome Zinc Zinc-finger | MSSPTSTPSR | MSSPTSTPSRRRNKRGRGSNPPTPHGEEVQSPPSQRRRTEDSTSIGELLPMPTSPSGDVQSPSGQELLFSSPAPSRHSAHQSELDLSSPLTYGTPSSRVEGTPRSGIRGTPARQRPDLGSARKVKQVDLHSDQPAAEELVTSEQSLGQKLVIWGTDVNVATCKEKFQRFVQRFIDPSAKEEDNVGLDLNEPIYMQRLEEINVVGDPFLNIDCDHLRNFDQDLYRQLVCYPQEVIPTFDMAANEIFFERYPDSILEHQIQVRPYNALKTRNMRSLNPEDIDQLITISGMVIRTSQIIPEMQEAFFKCQVCAFTTRVEIDRG... | DNA replication initiation DNA unwinding involved in DNA replication premeiotic DNA replication regulation of DNA-templated DNA replication initiation chromatin; CMG complex; MCM complex ATP binding ATP hydrolysis activity chromatin binding DNA binding DNA helicase activity metal ion binding Xenopus laevis ATP-binding ... |
DNA replication initiation DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation nuclear DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication preme... | CMG complex; cytoplasm; DNA replication preinitiation complex; MCM complex; MCM core complex; nuclear pre-replicative complex; nuclear replication fork; nucleoplasm; nucleus; replication fork protection complex | ATP binding ATP hydrolysis activity DNA helicase activity DNA replication origin binding helicase activity single-stranded DNA binding | Saccharomyces cerevisiae | 3D-structure ATP-binding Cell cycle DNA replication DNA-binding Helicase Hydrolase Nucleotide-binding Nucleus Phosphoprotein Reference proteome | MSQQSSSPTK | MSQQSSSPTKEDNNSSSPVVPNPDSVPPQLSSPALFYSSSSSQGDIYGRNNSQNLSQGEGNIRAAIGSSPLNFPSSSQRQNSDVFQSQGRQGRIRSSASASGRSRYHSDLRSDRALPTSSSSLGRNGQNRVHMRRNDIHTSDLSSPRRIVDFDTRSGVNTLDTSSSSAPPSEASEPLRIIWGTNVSIQECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCKGMRELNPN... | DNA replication initiation DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation nuclear DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication preme... |
DNA duplex unwinding DNA strand elongation involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation premeiotic DNA replication | chromatin; cytosol; DNA replication preinitiation complex; MCM complex; nuclear pre-replicative complex; nuclear replication fork; nucleus | ATP binding ATP hydrolysis activity DNA replication origin binding helicase activity single-stranded DNA binding | Schizosaccharomyces pombe | ATP-binding DNA replication DNA-binding Helicase Hydrolase Nucleotide-binding Nucleus Reference proteome | MTELLADEVF | MTELLADEVFKDRVRIFQEYLEHDTDDANVTLYQEAILRMLNMGQRRLIVNIDELRDYNRELADGVLLKPLEYVEPFDEALRNVVSTLIDPVVHKDLKDKLFYVGFRGSFGDHHVNPRTLRAMHLNKMISLEGIVTRCSFVRPKVIKSVHYCEATKRHHFKQYADATMNGGLSFQSTVYPTQDENGNPLSIEFGFSTFRDHQSISLQEMPERAPPGQLPRSIDILLDDDLVDTVKPGDRVNIVGQYRSMGSKTSGNTSATFRTVLLANNVVLLGNKPGLGNVGGGALDITDADIRNINKLARKKNVFELLSTSLAPSIYG... | DNA duplex unwinding DNA strand elongation involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation premeiotic DNA replication chromatin; cytosol; DNA replication preinitiation complex; MCM complex; nuclear pre-replicative complex; nuclear replication fork;... |
action potential adenylate cyclase-modulating G protein-coupled receptor signaling pathway calcium-mediated signaling G protein-coupled receptor signaling pathway phospholipase C-activating dopamine receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway | heterotrimeric G-protein complex | G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding | Mus musculus | GTP-binding Magnesium Metal-binding Nucleotide-binding Reference proteome Transducer | MARSLTWGCC | MARSLTWGCCPWCLTEEEKTAARIDQEINRILLEQKKQEREELKLLLLGPGESGKSTFIKQMRIIHGVGYSEEDRRAFRLLIYQNIFVSMQAMIDAMDRLQIPFSRPDSKQHASLVMTQDPYKVSTFEKPYAVAMQYLWRDAGIRACYERRREFHLLDSAVYYLSHLERISEDSYIPTAQDVLRSRMPTTGINEYCFSVKKTKLRIVDVGGQRSERRKWIHCFENVIALIYLASLSEYDQCLEENDQENRMEESLALFSTILELPWFKSTSVILFLNKTDILEDKIHTSHLATYFPSFQGPRRDAEAAKSFILDMYARVY... | action potential adenylate cyclase-modulating G protein-coupled receptor signaling pathway calcium-mediated signaling G protein-coupled receptor signaling pathway phospholipase C-activating dopamine receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway heterotrimeric G-prote... |
action potential activation of phospholipase C activity adenylate cyclase-modulating G protein-coupled receptor signaling pathway calcium-mediated signaling phospholipase C-activating dopamine receptor signaling pathway phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway | heterotrimeric G-protein complex; plasma membrane; synapse | G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding | Homo sapiens | ADP-ribosylation GTP-binding Magnesium Metal-binding Nucleotide-binding Reference proteome Transducer | MARSLTWRCC | MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMY... | action potential activation of phospholipase C activity adenylate cyclase-modulating G protein-coupled receptor signaling pathway calcium-mediated signaling phospholipase C-activating dopamine receptor signaling pathway phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway heterotrimeric... |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway cellular response to estradiol stimulus cellular response to glucocorticoid stimulus cerebellum development forebrain development G protein-coupled receptor signaling pathway neuropeptide signaling pathway peristalsis response to starvation somat... | cytosol; membrane; neuron projection; plasma membrane | neuropeptide binding PDZ domain binding somatostatin receptor activity | Rattus norvegicus | 3D-structure Alternative splicing Cell membrane Cytoplasm Direct protein sequencing Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MELTSEQFNG | MELTSEQFNGSQVWIPSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFK... | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway cellular response to estradiol stimulus cellular response to glucocorticoid stimulus cerebellum development forebrain development G protein-coupled receptor signaling pathway neuropeptide signaling pathway peristalsis response to starvation somat... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Pan troglodytes | Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MRVTAPRTLL | MRVTAPRTLLLLLSGGLALTETWAGSHSLRYFDTAVSRPGRREPRFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQWMYGCDLGPDGRLLRGYGQSAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQLRAYLEGKRVESCRRYLENGKETLQRTECPKTHMTHHPVSDHEATLRCWALAFYPAEITLTWQRDGEDQIQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPEPLTLRWKPTSQPTIPIVGIVAGLAVLAV... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
C4 photosynthesis carbon fixation tricarboxylic acid cycle | cytoplasm | phosphoenolpyruvate carboxylase activity | Flaveria trinervia | 3D-structure Allosteric enzyme Carbon dioxide fixation Cytoplasm Lyase Magnesium Phosphoprotein Photosynthesis | MANRNVEKLA | MANRNVEKLASIDAQLRLLVPGKVSEDDKLVEYDALLLDKFLDILQDLHGEDLKEAVQQCYELSAEYEGKHDPKKLEELGSLLTSLDTGDSIVIAKAFSHMLNLANLAEELQIAYRRRIKLKSGDFADEANATTESDIEETFKRLVHKLNKSPEEVFDALKNQTVELVLTAHPTQSVRRSLLQKHGRIRNCLAQLYAKDITPDDKQELDEALHREIQAAFRTDEIRRTPPTPQDEMRAGMSYFHETIWKGVPKFLRRVDTALKNIGINERFPYNAPLIQFSSWMGGDRDGNPRVTPEVTRDVCLLARMMTSNMYFSQIED... | C4 photosynthesis carbon fixation tricarboxylic acid cycle cytoplasm phosphoenolpyruvate carboxylase activity Flaveria trinervia 3D-structure Allosteric enzyme Carbon dioxide fixation Cytoplasm Lyase Magnesium Phosphoprotein Photosynthesis MANRNVEKLA MANRNVEKLASIDAQLRLLVPGKVSEDDKLVEYDALLLDKFLDILQDLHGEDLKEAVQQCYELSAEYE... |
glutathione metabolic process | cytoplasm; cytosol; extracellular exosome | glutathione peroxidase activity glutathione transferase activity | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Reference proteome Transferase | MGLELYLDLL | MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDGDFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKAKDFPPADPTIKQKLMPWVLAMIR | glutathione metabolic process cytoplasm; cytosol; extracellular exosome glutathione peroxidase activity glutathione transferase activity Homo sapiens 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Reference proteome Transferase MGLELYLDLL MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALK... |
glutathione metabolic process response to salicylic acid | cytoplasm; cytosol; nucleus | glutathione peroxidase activity glutathione transferase activity | Rattus norvegicus | Cytoplasm Direct protein sequencing Nucleus Reference proteome Transferase | MGLELYLDLL | MGLELYLDLLSQPSRAVYIFAKKNGIPFQLRTVDLLKGQHLSEQFSQVNCLKKVPVLKDGSFVLTESTAILIYLSSKYQVADHWYPADLQARAQVHEYLGWHADNIRGTFGVLLWTKVLGPLIGVQVPEEKVERNRNSMVLALQRLEDKFLRDRAFIAGQQVTLADLMSLEELIQPVALGCNLFEGRPQLTAWRERVEAFLGAELCQEAHNPIMSVLGQAAKKTLPVPPPEAHASMMLRIARIP | glutathione metabolic process response to salicylic acid cytoplasm; cytosol; nucleus glutathione peroxidase activity glutathione transferase activity Rattus norvegicus Cytoplasm Direct protein sequencing Nucleus Reference proteome Transferase MGLELYLDLL MGLELYLDLLSQPSRAVYIFAKKNGIPFQLRTVDLLKGQHLSEQFSQVNCLKKVPVLKDGSFVLTE... |
feeding behavior G protein-coupled receptor signaling pathway neuropeptide signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway response to glucocorticoid | cilium; non-motile cilium; plasma membrane | G protein-coupled receptor activity neuropeptide receptor activity neuropeptide Y receptor activity | Mus musculus | Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix | MKVPPVLLLF | MKVPPVLLLFLLSSVRATEQPQVVTEHPSMEAALTGPNASSHFWANYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFTIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWVFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISITKGVIYIAVIWVMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLDLATFILLYLLPLFIISVAYARVAKKLWLCNTIGDVTTEQYLALRRKKKTTVKMLVLVVVLFALCWFPLNCYVLLLSSKAI... | feeding behavior G protein-coupled receptor signaling pathway neuropeptide signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway response to glucocorticoid cilium; non-motile cilium; plasma membrane G protein-coupled receptor activity neuropeptide receptor activity neuropeptide Y rec... |
negative regulation of endopeptidase activity negative regulation of interleukin-1 beta production type B pancreatic cell proliferation | collagen-containing extracellular matrix; cytolytic granule; cytoplasmic ribonucleoprotein granule; early endosome; extracellular exosome; extracellular region; extracellular space; membrane; secretory granule lumen | peptidase inhibitor activity serine-type endopeptidase inhibitor activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Endosome Lysosome Phosphoprotein Protease inhibitor Reference proteome Secreted Serine protease inhibitor | MEQLSSANTR | MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVH... | negative regulation of endopeptidase activity negative regulation of interleukin-1 beta production type B pancreatic cell proliferation collagen-containing extracellular matrix; cytolytic granule; cytoplasmic ribonucleoprotein granule; early endosome; extracellular exosome; extracellular region; extracellular space; me... |
Mo-molybdopterin cofactor biosynthetic process response to heat | molybdopterin synthase complex | 4 iron, 4 sulfur cluster binding cyclic pyranopterin monophosphate synthase activity GTP 3',8'-cyclase activity GTP binding metal ion binding S-adenosyl-L-methionine binding | Escherichia coli | 4Fe-4S Direct protein sequencing GTP-binding Iron Iron-sulfur Lyase Metal-binding Molybdenum cofactor biosynthesis Nucleotide-binding Reference proteome S-adenosyl-L-methionine | MASQLTDAFA | MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFARLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVASWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGI... | Mo-molybdopterin cofactor biosynthetic process response to heat molybdopterin synthase complex 4 iron, 4 sulfur cluster binding cyclic pyranopterin monophosphate synthase activity GTP 3',8'-cyclase activity GTP binding metal ion binding S-adenosyl-L-methionine binding Escherichia coli 4Fe-4S Direct protein sequencing G... |
Mo-molybdopterin cofactor biosynthetic process | cytosol; molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex; MPT synthase complex | nucleotide binding | Escherichia coli | 3D-structure Direct protein sequencing Isopeptide bond Molybdenum cofactor biosynthesis Nucleotide-binding Phosphoprotein Reference proteome | MIKVLFFAQV | MIKVLFFAQVRELVGTDATEVAADFPTVEALRQHMAAQSDRWALALEDGKLLAAVNQTLVSFDHPLTDGDEVAFFPPVTGG | Mo-molybdopterin cofactor biosynthetic process cytosol; molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex; MPT synthase complex nucleotide binding Escherichia coli 3D-structure Direct protein sequencing Isopeptide bond Molybdenum cofactor biosynthesis Nucleotide-binding Phosphoprotein Reference pro... |
Mo-molybdopterin cofactor biosynthetic process | cytosol; MPT synthase complex | molybdopterin synthase activity protein homodimerization activity | Escherichia coli | 3D-structure Direct protein sequencing Isopeptide bond Molybdenum cofactor biosynthesis Reference proteome Transferase | MAETKIVVGP | MAETKIVVGPQPFSVGEEYPWLAERDEDGAVVTFTGKVRNHNLGDSVNALTLEHYPGMTEKALAEIVDEARNRWPLGRVTVIHRIGELWPGDEIVFVGVTSAHRSSAFEAGQFIMDYLKTRAPFWKREATPEGDRWVEARESDQQAAKRW | Mo-molybdopterin cofactor biosynthetic process cytosol; MPT synthase complex molybdopterin synthase activity protein homodimerization activity Escherichia coli 3D-structure Direct protein sequencing Isopeptide bond Molybdenum cofactor biosynthesis Reference proteome Transferase MAETKIVVGP MAETKIVVGPQPFSVGEEYPWLAERDEDGA... |
D-methionine transport metabolic process methionine import across plasma membrane | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; Gram-negative-bacterium-type cell wall; membrane; methionine-importing ABC transporter complex | ABC-type D-methionine transporter activity ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter activity L-methionine transmembrane transporter activity | Escherichia coli | 3D-structure Allosteric enzyme Amino-acid transport ATP-binding Cell inner membrane Cell membrane Membrane Nucleotide-binding Reference proteome Translocase Transport | MIKLSNITKV | MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGNVALPLELDNTPKDEVKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGELIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQ... | D-methionine transport metabolic process methionine import across plasma membrane ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; Gram-negative-bacterium-type cell wall; membrane; methionine-importing ABC transporter complex ABC-type D-methionine transporter activity ATP binding AT... |
cytoplasmic RNA surveillance DNA duplex unwinding DNA recombination intracellular mRNA localization nuclear-transcribed mRNA catabolic process nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay protein ubiquitinati... | cytoplasm | ATP binding ATP hydrolysis activity double-stranded DNA helicase activity mRNA binding ribosomal small subunit binding RNA binding RNA helicase activity single-stranded DNA binding zinc ion binding | Saccharomyces cerevisiae | 3D-structure ATP-binding Cytoplasm Helicase Hydrolase Metal-binding Nonsense-mediated mRNA decay Nucleotide-binding Phosphoprotein Reference proteome Zinc Zinc-finger | MVGSGSHTPY | MVGSGSHTPYDISNSPSDVNVQPATQLNSTLVEDDDVDNQLFEEAQVTETGFRSPSASDNSCAYCGIDSAKCVIKCNSCKKWFCNTKNGTSSSHIVNHLVLSHHNVVSLHPDSDLGDTVLECYNCGRKNVFLLGFVSAKSEAVVVLLCRIPCAQTKNANWDTDQWQPLIEDRQLLSWVAEQPTEEEKLKARLITPSQISKLEAKWRSNKDATINDIDAPEEQEAIPPLLLRYQDAYEYQRSYGPLIKLEADYDKQLKESQALEHISVSWSLALNNRHLASFTLSTFESNELKVAIGDEMILWYSGMQHPDWEGRGYIVRL... | cytoplasmic RNA surveillance DNA duplex unwinding DNA recombination intracellular mRNA localization nuclear-transcribed mRNA catabolic process nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay protein ubiquitinati... |
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