Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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anterior/posterior pattern specification DNA-templated transcription embryonic skeletal system morphogenesis negative regulation of cell cycle proximal/distal pattern formation regulation of transcription by RNA polymerase II | aggresome; chromatin; nucleoplasm; nucleus; transcription repressor complex | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | 3D-structure Developmental protein DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MSATGPISNY | MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS | anterior/posterior pattern specification DNA-templated transcription embryonic skeletal system morphogenesis negative regulation of cell cycle proximal/distal pattern formation regulation of transcription by RNA polymerase II aggresome; chromatin; nucleoplasm; nucleus; transcription repressor complex DNA-binding transc... |
anatomical structure morphogenesis anterior/posterior pattern specification hair follicle development nail development positive regulation of DNA-templated transcription regulation of transcription by RNA polymerase II tongue morphogenesis | chromatin; nucleus | chromatin binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequen... | Homo sapiens | Developmental protein Disease variant DNA-binding Ectodermal dysplasia Homeobox Nucleus Reference proteome Transcription Transcription regulation | MTTSLLLHPR | MTTSLLLHPRWPESLMYVYEDSAAESGIGGGGGGGGGGTGGAGGGCSGASPGKAPSMDGLGSSCPASHCRDLLPHPVLGRPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFGGSYYGCRLSHNVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKKVVS... | anatomical structure morphogenesis anterior/posterior pattern specification hair follicle development nail development positive regulation of DNA-templated transcription regulation of transcription by RNA polymerase II tongue morphogenesis chromatin; nucleus chromatin binding DNA-binding transcription activator activit... |
anterior/posterior axis specification, embryo canonical Wnt signaling pathway cell migration involved in gastrulation dorsal/ventral axis specification negative regulation of canonical Wnt signaling pathway positive regulation of transcription by RNA polymerase II Spemann organizer formation | extracellular region; protein-containing complex | frizzled binding Wnt-protein binding | Xenopus laevis | Developmental protein Disulfide bond Extracellular matrix Glycoprotein Lipoprotein Reference proteome Secreted Signal Wnt signaling pathway | MRKNLWTFQF | MRKNLWTFQFGGEASGLVGSAMVSQHFVVLLMSLYCLTQSVVESSSWWSLGMNPVQMPEVYIIGAQPLCSQLSGLSQGQKKLCQLYQDHMQFIGDGAKTGIKECQYQFRHRRWNCSTVDNTSVFGRVMQIGSRETAFTYAISAAGVVNAVSRACREGELSTCGCSRAARPKDLPRDWLWGGCGDNLDYGYRFAKEFVDAREREKIHQKGSYESSRIMMNLHNNEAGRRAVSTLADVACKCHGVSGSCSLKTCWLQLADFRKVGDHLKEKYDSAGAMKLNTRGKLVQVNNKFNSPTMNDLVYIDPSPDYCVHNESTGSLGT... | anterior/posterior axis specification, embryo canonical Wnt signaling pathway cell migration involved in gastrulation dorsal/ventral axis specification negative regulation of canonical Wnt signaling pathway positive regulation of transcription by RNA polymerase II Spemann organizer formation extracellular region; prote... |
anterior/posterior pattern specification embryonic limb morphogenesis male gonad development positive regulation of transcription by RNA polymerase II prostate gland development proximal/distal pattern formation regulation of gene expression regulation of transcription by RNA polymerase II response to estrogen response... | cytoplasm; nucleoplasm; nucleus; transcription regulator complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific histone deacetylase binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Alternative splicing Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MSARKGYLLP | MSARKGYLLPSPNYPTTMSCSESPAANSFLVDSLISSGRGEAGVGGGSAGGGGGGYYAHGGVYLPPASDLPYGLQSCGLFPALGSKRNEAPSPGGGGGGGSGGLGPGTHGYAPAPLDLWLDAPRSCRMEPPDGPPPPQPQPQQQQQQPPPPPPQPPQPQPQATSCSFAQNIKEESSYCLYDAADKCPKGSAAADLAPFPRGPPPDGCALGASSGVPVPGYFRLSQAYGTAKGFGSGGGGTQQLASPFPAQPPGRGFDPPPALASGSTEAAGKERVLDSTPPPTLVCTGGGGSQGDEEAHASSSAAEELSPAPSENSKASP... | anterior/posterior pattern specification embryonic limb morphogenesis male gonad development positive regulation of transcription by RNA polymerase II prostate gland development proximal/distal pattern formation regulation of gene expression regulation of transcription by RNA polymerase II response to estrogen response... |
anatomical structure development anterior/posterior pattern specification embryonic digit morphogenesis embryonic skeletal joint morphogenesis metanephros development organ induction positive regulation of transcription by RNA polymerase II proximal/distal pattern formation regulation of transcription by RNA polymerase... | cytosol; nucleoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Developmental protein DNA-binding Homeobox Isopeptide bond Nucleus Reference proteome Transcription Transcription regulation Ubl conjugation | MFNSVNLGNF | MFNSVNLGNFCSPSRKERGADFGERGSCTSNLYLPSCTYYVPEFSTVSSFLPQAPSRQISYPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPSTVTEILMKNEGSYGGHHHPSAPHAAPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDAPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEAEEENTNPSSSGSSHSATKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSGNPLL | anatomical structure development anterior/posterior pattern specification embryonic digit morphogenesis embryonic skeletal joint morphogenesis metanephros development organ induction positive regulation of transcription by RNA polymerase II proximal/distal pattern formation regulation of transcription by RNA polymerase... |
animal organ development regulation of transcription by RNA polymerase II | chromatin; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Homo sapiens | Acetylation Alternative splicing Chromosomal rearrangement Developmental protein DNA-binding Homeobox Nucleus Proto-oncogene Reference proteome | MEHLGPHHLH | MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGGGSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESNRRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKIT... | animal organ development regulation of transcription by RNA polymerase II chromatin; nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding Homo sapiens A... |
adenohypophysis development central nervous system development hypothalamus development neuron differentiation neuron fate commitment positive regulation of transcription by RNA polymerase II spinal cord association neuron differentiation transcription by RNA polymerase II | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Activator Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MPRSFLVDSL | MPRSFLVDSLVLREASDKKAPEGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQYCHAPLGRQHSVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGAGAGAGGGAPQGCKCSSLSSAKCSEDDDELPMSPSSSGKDDRDLTVTP | adenohypophysis development central nervous system development hypothalamus development neuron differentiation neuron fate commitment positive regulation of transcription by RNA polymerase II spinal cord association neuron differentiation transcription by RNA polymerase II nucleus DNA-binding transcription activator ac... |
brain development central nervous system development forebrain dorsal/ventral pattern formation forebrain morphogenesis GABAergic neuron differentiation generation of neurons hindbrain morphogenesis neuron fate commitment neuron fate specification Notch signaling pathway olfactory bulb development olfactory bulb intern... | cytoplasm; nucleus | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific sequence-specific double-stranded DNA binding | Mus musculus | Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MSRSFYVDSL | MSRSFYVDSLIIKDSSRPAPSLPESHPGPDFFIPLGMPSPLVMSVSGPGCPSRKSGAFCVCPLCVTSHLHSSRPPAGAGGGATGTAGAAVAGGGVAGGTGALPLLKSQFSPAPGDAQFCPRVSHAHHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAAALGHPQHHAPVCAATTYNMSDPRRFHCLSMGGSDTSQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGASRNNHTSCKCVGSQAHYARSEDEDSLSPASANEDKEISPL | brain development central nervous system development forebrain dorsal/ventral pattern formation forebrain morphogenesis GABAergic neuron differentiation generation of neurons hindbrain morphogenesis neuron fate commitment neuron fate specification Notch signaling pathway olfactory bulb development olfactory bulb intern... |
arginine biosynthetic process via ornithine citrulline biosynthetic process urea cycle | cytoplasm; mitochondrial matrix; mitochondrion | amino acid binding ornithine carbamoyltransferase activity | Schizosaccharomyces pombe | Amino-acid biosynthesis Arginine biosynthesis Mitochondrion Reference proteome Transferase Transit peptide | MSFKKFPRHL | MSFKKFPRHLLSIRDLSRGEIVKLIDRSSEIKQAYKQNFQNRRSVQMSGLSSQNVAMIFSKRSTRTRVSVESAVSCLGGNAMFLGKDDIQLGVNESLYDTSKVISSMVSGIVARVNKYSDVATLAKHASCPVINGLCDTFHPLQALADLLTIKETFKSFDGLKVAWVGDANNVLHDLMIANAKVGIHTSVAKPKDVNVRDDILSIVNEAANENGSTFEIVNDPKVAVKNADIVVTDTWISMGQEAEKEQRLKQFTGFQVTGEIMKLAKPSCKFMHCLPRHPEEVSDEVFYGENSLVFQEAENRKWTTVAVLEALLVNRGE... | arginine biosynthetic process via ornithine citrulline biosynthetic process urea cycle cytoplasm; mitochondrial matrix; mitochondrion amino acid binding ornithine carbamoyltransferase activity Schizosaccharomyces pombe Amino-acid biosynthesis Arginine biosynthesis Mitochondrion Reference proteome Transferase Transit p... |
arginine biosynthetic process ornithine biosynthetic process phosphorylation | mitochondrial matrix; mitochondrion | acetylglutamate kinase activity ATP binding N-acetyl-gamma-glutamyl-phosphate reductase activity NAD binding NADP+ binding | Schizosaccharomyces pombe | Amino-acid biosynthesis Arginine biosynthesis ATP-binding Cleavage on pair of basic residues Kinase Mitochondrion Multifunctional enzyme NADP Nucleotide-binding Oxidoreductase Reference proteome Transferase Transit peptide | MLIELQQIVK | MLIELQQIVKSGLVRNGAKHCTKRSLLCSNASVIASKRFQGSFAPGQQQPLNPLAKPIEQDRDAIIRILSSIGSRREVEQYLRYFTSFEAQRFAIIKVGGAIITDELDTLAQSLAFLNHVGLYPIVVHGAGPQLNKILASRNVEPEYSDGIRITDAETLSVARKVFLEENAKLVDALEKLGTRARPITGGVFQAEYLDKEKYKYVGKIVKVNKAPIEHSIRAGTLPILTSMAETASGQLLNVNADITAGELARVLKPLKVVYLNEKGGLINGETKKKISSIYLDREYDGLMKQPWVKYGTKLKIKEIKELLDTLPRTSSV... | arginine biosynthetic process ornithine biosynthetic process phosphorylation mitochondrial matrix; mitochondrion acetylglutamate kinase activity ATP binding N-acetyl-gamma-glutamyl-phosphate reductase activity NAD binding NADP+ binding Schizosaccharomyces pombe Amino-acid biosynthesis Arginine biosynthesis ATP-binding... |
learning or memory negative regulation of cAMP-dependent protein kinase activity positive regulation of excitatory postsynaptic potential positive regulation of fear response positive regulation of long-term synaptic potentiation protein phosphorylation regulation of synaptic vesicle cycle | cAMP-dependent protein kinase complex; ciliary base; cytosol; glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; multivesicular body; plasma membrane; postsynapse; Schaffer collateral - CA1 synapse | cAMP binding cAMP-dependent protein kinase inhibitor activity cAMP-dependent protein kinase regulator activity protein kinase A catalytic subunit binding | Homo sapiens | 3D-structure cAMP cAMP-binding Cell membrane Disease variant Disulfide bond Intellectual disability Membrane Methylation Nitration Nucleotide-binding Phosphoprotein Reference proteome Repeat | MASPPACPSE | MASPPACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSNSQSDSHDEEVSPTPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGP... | learning or memory negative regulation of cAMP-dependent protein kinase activity positive regulation of excitatory postsynaptic potential positive regulation of fear response positive regulation of long-term synaptic potentiation protein phosphorylation regulation of synaptic vesicle cycle cAMP-dependent protein kinase... |
fatty acid metabolic process intracellular signal transduction learning modulation of chemical synaptic transmission negative regulation of cAMP-dependent protein kinase activity response to antipsychotic drug | cAMP-dependent protein kinase complex; centrosome; ciliary base; cytoplasm; cytosol; dendritic shaft; dendritic spine; extracellular exosome; glutamatergic synapse; neuronal cell body; perinuclear region of cytoplasm; plasma membrane | cAMP binding cAMP-dependent protein kinase inhibitor activity cAMP-dependent protein kinase regulator activity protein domain specific binding protein kinase A catalytic subunit binding ubiquitin protein ligase binding | Homo sapiens | cAMP cAMP-binding Cell membrane Cytoplasm Membrane Nucleotide-binding Phosphoprotein Reference proteome Repeat | MSIEIPAGLT | MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGTARFGHEGRTWGDLGAAAGGGTPSKGVNFAEEPMQSDSEDGEEEEAAPADAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGE... | fatty acid metabolic process intracellular signal transduction learning modulation of chemical synaptic transmission negative regulation of cAMP-dependent protein kinase activity response to antipsychotic drug cAMP-dependent protein kinase complex; centrosome; ciliary base; cytoplasm; cytosol; dendritic shaft; dendriti... |
fatty acid metabolic process learning modulation of chemical synaptic transmission regulation of protein phosphorylation response to antipsychotic drug | cAMP-dependent protein kinase complex; centrosome; ciliary base; cytoplasm; cytosol; dendrite; dendritic shaft; dendritic spine; glutamatergic synapse; neuronal cell body; perinuclear region of cytoplasm; plasma membrane; postsynapse | cAMP binding cAMP-dependent protein kinase inhibitor activity cAMP-dependent protein kinase regulator activity protein domain specific binding protein kinase A catalytic subunit binding protein kinase binding ubiquitin protein ligase binding | Mus musculus | 3D-structure cAMP cAMP-binding Cell membrane Cytoplasm Membrane Nucleotide-binding Phosphoprotein Reference proteome Repeat | MSIEIPAGLT | MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVK... | fatty acid metabolic process learning modulation of chemical synaptic transmission regulation of protein phosphorylation response to antipsychotic drug cAMP-dependent protein kinase complex; centrosome; ciliary base; cytoplasm; cytosol; dendrite; dendritic shaft; dendritic spine; glutamatergic synapse; neuronal cell bo... |
glycogen biosynthetic process glycogen catabolic process glycogen metabolic process phosphorylation | cytosol; phosphorylase kinase complex | ATP binding calmodulin binding enzyme binding phosphorylase kinase activity | Rattus norvegicus | ATP-binding Calmodulin-binding Carbohydrate metabolism Glycogen metabolism Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MTLDVGPEDE | MTLDVGPEDELPDWAAAKEFYQKYDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVNFLHVNNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSNTVKDLIAKLLQVDPNARLTAEQALQHPFFERCKGSQPWNLTPRQRFRVAVWTILAAGR... | glycogen biosynthetic process glycogen catabolic process glycogen metabolic process phosphorylation cytosol; phosphorylase kinase complex ATP binding calmodulin binding enzyme binding phosphorylase kinase activity Rattus norvegicus ATP-binding Calmodulin-binding Carbohydrate metabolism Glycogen metabolism Kinase Nucleo... |
de novo' IMP biosynthetic process | cytosol | IMP cyclohydrolase activity phosphoribosylaminoimidazolecarboxamide formyltransferase activity protein homodimerization activity | Gallus gallus | 3D-structure Acetylation Cytoplasm Hydrolase Multifunctional enzyme Purine biosynthesis Reference proteome Transferase | MAARQQLALL | MAARQQLALLSVSEKAGLVEFARSLNALGLGLIASGGTATALRDAGLPVRDVSDLTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMNKQDFSLVRVVVCNLYPFVKTVSSPGVTVPEAVEKIDIGGVALLRAAAKNHARVTVVCDPADYSSVAKEMAASKDKDTSVETRRHLALKAFTHTAQYDAAISDYFRKEYSKGVSQLPLRYGMNPHQSPAQLYTTRPKLPLTVVNGSPGFINLCDALNAWQLVKELKQALGIPAAASFKHVSPAGAAVGIPLSEEEAQVCMVHDLHKTLTPLASAYARSRGADRMSSFGDFI... | de novo' IMP biosynthetic process cytosol IMP cyclohydrolase activity phosphoribosylaminoimidazolecarboxamide formyltransferase activity protein homodimerization activity Gallus gallus 3D-structure Acetylation Cytoplasm Hydrolase Multifunctional enzyme Purine biosynthesis Reference proteome Transferase MAARQQLALL MAARQ... |
actin filament polymerization activation of phospholipase A2 activity activation of phospholipase C activity angiogenesis cell differentiation diacylglycerol biosynthetic process negative regulation of smooth muscle cell proliferation negative regulation of translation positive regulation of endothelial cell proliferat... | angiogenin-PRI complex; basement membrane; cytoplasmic vesicle; extracellular space; nucleolus; nucleus | actin binding copper ion binding DNA binding endonuclease activity heparin binding protein homodimerization activity RNA nuclease activity signaling receptor binding | Oryctolagus cuniculus | Angiogenesis Cytoplasmic vesicle Developmental protein Differentiation Direct protein sequencing Disulfide bond DNA-binding Endonuclease Hydrolase Nuclease Nucleus Protein synthesis inhibitor Pyrrolidone carboxylic acid Reference proteome Secreted Stress response | QDDSRYKHFL | QDDSRYKHFLTQHYDAKPFGRNDRYCETMMKRRDLTSPCKDTNTFVHGNKGSIKDVCEDKNGKPYGKNFRISKSSFQVTTCKHVGGSPWPPCRYRATSGSRNIVIACENGLPVHFDESVFQQKVH | actin filament polymerization activation of phospholipase A2 activity activation of phospholipase C activity angiogenesis cell differentiation diacylglycerol biosynthetic process negative regulation of smooth muscle cell proliferation negative regulation of translation positive regulation of endothelial cell proliferat... |
2'-deoxyribonucleotide biosynthetic process blastocyst development deoxyribonucleotide biosynthetic process positive regulation of G1/S transition of mitotic cell cycle protein heterotetramerization ribonucleoside diphosphate metabolic process | cytosol; nucleus; ribonucleoside-diphosphate reductase complex | ferric iron binding protein homodimerization activity ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Deoxyribonucleotide synthesis Iron Metal-binding Nucleus Oxidoreductase Phosphoprotein Reference proteome Ubl conjugation | MLSLRVPLAP | MLSLRVPLAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGMNCTLM... | 2'-deoxyribonucleotide biosynthetic process blastocyst development deoxyribonucleotide biosynthetic process positive regulation of G1/S transition of mitotic cell cycle protein heterotetramerization ribonucleoside diphosphate metabolic process cytosol; nucleus; ribonucleoside-diphosphate reductase complex ferric iron b... |
phototransduction visual perception | cell projection; membrane; plasma membrane | G protein-coupled receptor activity photoreceptor activity retinal binding | Todarodes pacificus | 3D-structure Cell membrane Cell projection Chromophore Direct protein sequencing Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Photoreceptor protein Receptor Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Vision | MGRDLRDNET | MGRDLRDNETWWYNPSIVVHPHWREFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFLKKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYISRDSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLNAKELRKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEWVTPYAAQLPVMFAKASAIHNPMIYSVSHP... | phototransduction visual perception cell projection; membrane; plasma membrane G protein-coupled receptor activity photoreceptor activity retinal binding Todarodes pacificus 3D-structure Cell membrane Cell projection Chromophore Direct protein sequencing Disulfide bond G-protein coupled receptor Glycoprotein Lipoprote... |
cellular response to organic substance cerebral cortex radially oriented cell migration epidermis development forebrain astrocyte development forebrain ventricular zone progenitor cell division hypothalamus cell differentiation myelination in peripheral nervous system negative regulation of gene expression nervous syst... | nucleoplasm; nucleus; transcription regulator complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific HMG box domain binding identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequ... | Mus musculus | Activator Differentiation DNA-binding Homeobox Neurogenesis Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MATAASNHYS | MATAASNHYSLLTSSASIVHAEPPGGMQQGAGGYREAQSLVQGDYGALQSNGHPLSHAHQWITALSHGGGGGGGGGGGGGGGGGGGGGDGSPWSTSPLGQPDIKPSVVVQQGGRGDELHGPGALQQQHQQQQQQQQQQQQQQQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSMGASNGGLLYSQPSFTVNGMLGAGGQPAGLHHHGLRDAHDEPHHADHHPHPHSHPHQQPPPPPPPQGPPGHPGAHHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSF... | cellular response to organic substance cerebral cortex radially oriented cell migration epidermis development forebrain astrocyte development forebrain ventricular zone progenitor cell division hypothalamus cell differentiation myelination in peripheral nervous system negative regulation of gene expression nervous syst... |
cerebral cortex radially oriented cell migration chemical homeostasis forebrain ventricular zone progenitor cell division kidney development metanephric ascending thin limb development metanephric DCT cell differentiation metanephric loop of Henle development metanephric macula densa development metanephric thick ascen... | nucleoplasm; nucleus | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific HMG box domain binding protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Mus musculus | Developmental protein DNA-binding Homeobox Neurogenesis Nucleus Reference proteome Transcription Transcription regulation | MATAASNPYL | MATAASNPYLPGNSLLTAGSIVHSDAAGAGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGREDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGAGPGLNSHDPHSDEDTPTSDDLE... | cerebral cortex radially oriented cell migration chemical homeostasis forebrain ventricular zone progenitor cell division kidney development metanephric ascending thin limb development metanephric DCT cell differentiation metanephric loop of Henle development metanephric macula densa development metanephric thick ascen... |
cell differentiation epidermis development keratinocyte differentiation negative regulation by host of viral transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II wound healing | cytosol; nuclear body; nucleolus; nucleoplasm; nucleus; plasma membrane; transcription regulator complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA b... | Mus musculus | DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MVNLEPMHTE | MVNLEPMHTEIKMSGDVADSTDTRSTFGQVEPGNDRNGLDFNRQIKTEDLGDSLQQTLSHRPCHLSQGPTMMPGNQMSGDMASLHPLQQLVLVPGHLQSVSQFLLSQTPPGQQGLQPNLLSFPQQQSTLLLPQTGPGLASQAVGRPGLSGSSLEPHLDAPQHLPGPKHLPGPGGNDEPTDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSASTPSSYPTLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRV... | cell differentiation epidermis development keratinocyte differentiation negative regulation by host of viral transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II wound healing cytosol; nuclear body; nucleolus; nucleoplasm; nucleus; plasma membrane; tra... |
appendage morphogenesis dendrite morphogenesis negative regulation of antibacterial peptide biosynthetic process regulation of neural precursor cell proliferation regulation of neurogenesis regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription cis-regulatory region binding | Drosophila melanogaster | Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MVMSELRWHT | MVMSELRWHTASPEDNKNSLKRDLLKSTPTSAREAAVHIMQNRYISRLSRSPSPLQSNASDCDDNNSSVGTSSDRCRSPLSPALSLSHQQAKRQLMSLQPHPAHHHHNPHHLNHLNHHQYKQEEDYDDANGGALNLTSDNSRHSTQSPSNSVKSATASPVPVISVPSPVPPMISPVLAPSGCGSTTPNSMAAAAAAAAAVASTMGSGISPLLALPGMSSPQAQLAAAGLGMNNPLLTGSLSPQDFAQFHQLLQQRQVALTQQFNSYMELLRSGSLGLAQDDPALTAQVAAAQFLMQSQLQALSQASQQLQALQKQQQRQV... | appendage morphogenesis dendrite morphogenesis negative regulation of antibacterial peptide biosynthetic process regulation of neural precursor cell proliferation regulation of neurogenesis regulation of transcription by RNA polymerase II nucleus DNA-binding transcription activator activity, RNA polymerase II-specific ... |
central nervous system development ectoderm development generation of neurons neuroblast development regulation of DNA-templated transcription regulation of transcription by RNA polymerase II | nucleus | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Drosophila melanogaster | Activator Alternative splicing Developmental protein DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MMVLQQQQQQ | MMVLQQQQQQRLWDATTTSNTNTQTQQSANVESTPTKVCHQENAATHTFMRHMSNSPTPPSPLRSLSDCGKSFEEEELELGENCEMPQNLSSKRQARELDSELENEVLDLAPPPKRLAEEQEEEKVASVNPPQPVAFAPEEMHQALQLQLHSYIEMVRQLAPEAFPNPNLATQFLLQNSLQALAQFQALQQMKQQQREDPLPSYSTPLAKSPLRSPSLSPVPRHSKSQQRTPPNSMTANSLGMSSAVMTPNTPSMQQQPQLQQSTPKPTSGLTVASAMAKLEQSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMG... | central nervous system development ectoderm development generation of neurons neuroblast development regulation of DNA-templated transcription regulation of transcription by RNA polymerase II nucleus DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor ac... |
cysteine biosynthetic process cysteine biosynthetic process via cystathionine positive regulation of hydrogen sulfide biosynthetic process transsulfuration | cytoplasm; nucleus | cystathionine gamma-lyase activity cysteine-S-conjugate beta-lyase activity L-cysteine desulfhydrase activity L-cystine L-cysteine-lyase (deaminating) pyridoxal phosphate binding | Saccharomyces cerevisiae | 3D-structure Amino-acid biosynthesis Cysteine biosynthesis Cytoplasm Direct protein sequencing Lyase Phosphoprotein Pyridoxal phosphate Reference proteome | MTLQESDKFA | MTLQESDKFATKAIHAGEHVDVHGSVIEPISLSTTFKQSSPANPIGTYEYSRSQNPNRENLERAVAALENAQYGLAFSSGSATTATILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGVETSFTNDLLNDLPQLIKENTKLVWIETPTNPTLKVTDIQKVADLIKKHAAGQDVILVVDNTFLSPYISNPLNFGADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQNAIGAIPSPFDAWLTHRGLKTLHLRVRQAALSANKIAEFLAADKENVVAVNYPGLKTHPNYDVVLKQHRDALGGGMISFRIKGGAEAA... | cysteine biosynthetic process cysteine biosynthetic process via cystathionine positive regulation of hydrogen sulfide biosynthetic process transsulfuration cytoplasm; nucleus cystathionine gamma-lyase activity cysteine-S-conjugate beta-lyase activity L-cysteine desulfhydrase activity L-cystine L-cysteine-lyase (deamina... |
chromatin remodeling endoplasmic reticulum organization regulation of DNA-templated transcription | chromatin; mitochondrion; nucleus; Swr1 complex | ATP-dependent H2AZ histone chaperone activity | Saccharomyces cerevisiae | Activator Chromatin regulator Nucleus Reference proteome Transcription Transcription regulation | MPAVLRTRSK | MPAVLRTRSKESSIEQKPASRTRTRSRRGKRGRDDDDDDDDEESDDAYDEVGNDYDEYASRAKLATNRPFEIVAGLPASVELPNYNSSLTHPQSIKNSGVLYDSLVSSRRTWVQGEMFELYWRRPKKIVSESTPAATESPTSGTIPLIRDKMQKMCDCVMSGGPHTFKVRLFILKNDKIEQKWQDEQELKKKEKELKRKNDAEAKRLRMEERKRQQMQKKIAKEQKLQLQKENKAKQKLEQEALKLKRKEEMKKLKEQNKNKQGSPSSSMHDPRMIMNLNLMAQEDPKLNTLMETVAKGLANNSQLEEFKKFIEIAKKRS... | chromatin remodeling endoplasmic reticulum organization regulation of DNA-templated transcription chromatin; mitochondrion; nucleus; Swr1 complex ATP-dependent H2AZ histone chaperone activity Saccharomyces cerevisiae Activator Chromatin regulator Nucleus Reference proteome Transcription Transcription regulation MPAVLR... |
Golgi to endosome transport Golgi to vacuole transport Golgi vesicle fusion to target membrane intracellular protein transport vesicle docking vesicle fusion | cytosol; endomembrane system; endosome; endosome membrane; Golgi membrane; SNARE complex | SNAP receptor activity SNARE binding | Saccharomyces cerevisiae | Coiled coil Endosome Lipoprotein Membrane Palmitate Protein transport Reference proteome Transmembrane Transmembrane helix Transport | MDVLKLGYEL | MDVLKLGYELDQLSDLVEERTRLVSVLKLAPTSNDNVTLKRQLGSILELLQKCAPNDELISRYNTILDKIPDTAVDKELYRFQQQVARNTDEVSKESLKKVRFKNDDELTVMYKDDDEQDEESPLPSTHTPYKDEPLQSQLQSQSQPQPPQPMVSNQELFINQQQQLLEQDSHLGALSQSIGRTHDISLDLNNEIVSQNDSLLVDLENLIDNNGRNLNRASRSMHGFNNSRFKDNGNCVIILVLIVVLLLLLLVL | Golgi to endosome transport Golgi to vacuole transport Golgi vesicle fusion to target membrane intracellular protein transport vesicle docking vesicle fusion cytosol; endomembrane system; endosome; endosome membrane; Golgi membrane; SNARE complex SNAP receptor activity SNARE binding Saccharomyces cerevisiae Coiled coi... |
base-excision repair base-excision repair, AP site formation cellular response to oxidative stress DNA repair positive regulation of mitochondrial DNA replication | mitochondrion; nucleus | class I DNA-(apurinic or apyrimidinic site) endonuclease activity DNA binding DNA-(apurinic or apyrimidinic site) endonuclease activity oxidized purine nucleobase lesion DNA N-glycosylase activity oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity | Saccharomyces cerevisiae | DNA damage DNA repair Glycosidase Hydrolase Isopeptide bond Lyase Mitochondrion Nucleus Reference proteome Transit peptide Ubl conjugation | MQKISKYSSM | MQKISKYSSMAILRKRPLVKTETGPESELLPEKRTKIKQEEVVPQPVDIDWVKSLPNKQYFEWIVVRNGNVPNRWATPLDPSILVTPASTKVPYKFQETYARMRVLRSKILAPVDIIGGSSIPVTVASKCGISKEQISPRDYRLQVLLGVMLSSQTKDEVTAMAMLNIMRYCIDELHSEEGMTLEAVLQINETKLDELIHSVGFHTRKAKYILSTCKILQDQFSSDVPATINELLGLPGVGPKMAYLTLQKAWGKIEGICVDVHVDRLTKLWKWVDAQKCKTPDQTRTQLQNWLPKGLWTEINGLLVGFGQIITKSRNLG... | base-excision repair base-excision repair, AP site formation cellular response to oxidative stress DNA repair positive regulation of mitochondrial DNA replication mitochondrion; nucleus class I DNA-(apurinic or apyrimidinic site) endonuclease activity DNA binding DNA-(apurinic or apyrimidinic site) endonuclease activit... |
ER-associated misfolded protein catabolic process fungal-type cell wall biogenesis protein exit from endoplasmic reticulum protein O-linked glycosylation protein O-linked mannosylation regulation of endoplasmic reticulum unfolded protein response | dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex; dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex; endoplasmic reticulum; endoplasmic reticulum membrane | dolichyl-phosphate-mannose-protein mannosyltransferase activity | Saccharomyces cerevisiae | 3D-structure Acetylation Endoplasmic reticulum Glycoprotein Glycosyltransferase Membrane Phosphoprotein Reference proteome Repeat Transferase Transmembrane Transmembrane helix | MSSSSSTGYS | MSSSSSTGYSKNNAAHIKQENTLRQRESSSISVSEELSSADERDAEDFSKEKPAAQSSLLRLESVVMPVIFTALALFTRMYKIGINNHVVWDEAHFGKFGSYYLRHEFYHDVHPPLGKMLVGLSGYLAGYNGSWDFPSGEIYPDYLDYVKMRLFNASFSALCVPLAYFTAKAIGFSLPTVWLMTVLVLFENSYSTLGRFILLDSMLLFFTVASFFSFVMFHNQRSKPFSRKWWKWLLITGISLGCTISVKMVGLFIITMVGIYTVIDLWTFLADKSMSWKTYINHWLARIFGLIIVPFCIFLLCFKIHFDLLSHSGTGDA... | ER-associated misfolded protein catabolic process fungal-type cell wall biogenesis protein exit from endoplasmic reticulum protein O-linked glycosylation protein O-linked mannosylation regulation of endoplasmic reticulum unfolded protein response dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer ... |
mitotic spindle assembly checkpoint signaling regulation of translation | cellular bud neck; cellular bud tip; cytoplasm; mating projection tip; nucleus; protein phosphatase type 2A complex; spindle pole body | protein phosphatase regulator activity | Saccharomyces cerevisiae | Reference proteome Repeat | MSGARSTTAG | MSGARSTTAGAVPSAATTSTTSTTSNSKDSDSNESLYPLALLMDELKHDDIANRVEAMKKLDTIALALGPERTRNELIPFLTEVAQDDEDEVFAVLAEQLGKFVPYIGGPQYATILLPVLEILASAEETLVREKAVDSLNNVAQELSQEQLFSDFVPLIEHLATADWFSSKVSACGLFKSVIVRIKDDSLRKNILALYLQLAQDDTPMVKRAVGKNLPILIDLLTQNLGLSTDEDWDYISNIFQKIINDNQDSVKFLAVDCLISILKFFNAKGDESHTQDLLNSAVKLIGDEAWRVRYMAADRFSDLASQFSSNQAYIDE... | mitotic spindle assembly checkpoint signaling regulation of translation cellular bud neck; cellular bud tip; cytoplasm; mating projection tip; nucleus; protein phosphatase type 2A complex; spindle pole body protein phosphatase regulator activity Saccharomyces cerevisiae Reference proteome Repeat MSGARSTTAG MSGARSTTAGA... |
DNA replication DNA replication checkpoint signaling nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay nuclear-transcribed mRNA poly(A) tail shortening positive regulation of transcription elongation by RNA polymerase II regulation of transcription by RNA polymerase II transcription elongation b... | CCR4-NOT complex; CCR4-NOT core complex; Cdc73/Paf1 complex; cytoplasm; nucleus; P-body | 3'-5'-RNA exonuclease activity metal ion binding poly(A)-specific ribonuclease activity RNA binding | Saccharomyces cerevisiae | 3D-structure Activator Cytoplasm Exonuclease Hydrolase Leucine-rich repeat Magnesium Metal-binding Nuclease Nucleus Phosphoprotein Reference proteome Repeat Repressor RNA-binding Transcription Transcription regulation | MNDPSLLGYP | MNDPSLLGYPNVGPQQQQQQQQQQHAGLLGKGTPNALQQQLHMNQLTGIPPPGLMNNSDVHTSSNNNSRQLLDQLANGNANMLNMNMDNNNNNNNNNNNNNNNGGGSGVMMNASTAAVNSIGMVPTVGTPVNINVNASNPLLHPHLDDPSLLNNPIWKLQLHLAAVSAQSLGQPNIYARQNAMKKYLATQQAQQAQQQAQQQAQQQVPGPFGPGPQAAPPALQPTDFQQSHIAEASKSLVDCTKQALMEMADTLTDSKTAKKQQPTGDSTPSGTATNSAVSTPLTPKIELFANGKDEANQALLQHKKLSQYSIDEDDDIE... | DNA replication DNA replication checkpoint signaling nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay nuclear-transcribed mRNA poly(A) tail shortening positive regulation of transcription elongation by RNA polymerase II regulation of transcription by RNA polymerase II transcription elongation b... |
negative regulation of rDNA heterochromatin formation negative regulation of silent mating-type cassette heterochromatin formation negative regulation of transcription by RNA polymerase II nucleosome assembly positive regulation of transcription by RNA polymerase II regulation of DNA-templated DNA replication initiatio... | cytoplasm; nucleus; Rpd3L complex; Rpd3L-Expanded complex; Sin3-type complex | histone deacetylase binding | Saccharomyces cerevisiae | 3D-structure Chromatin regulator Cytoplasm Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation | MSQQTPQESE | MSQQTPQESEQTTAKEQDLDQESVLSNIDFNTDLNHNLNLSEYCISSDAGTEKMDSDEEKSLANLPELKYAPKLSSLVKQETLTESLKRPHEDEKEAIDEAKKMKVPGENEDESKEEEKSQELEEAIDSKEKSTDARDEQGDEGDNEEENNEEDNENENEHTAPPALVMPSPIEMEEQRMTALKEITDIEYKFAQLRQKLYDNQLVRLQTELQMCLEGSHPELQVYYSKIAAIRDYKLHRAYQRQKYELSCINTETIATRTFIHQDFHKKVTDLRARLLNRTTQTWYDINKERRDMDIVIPDVNYHVPIKLDNKTLSCIT... | negative regulation of rDNA heterochromatin formation negative regulation of silent mating-type cassette heterochromatin formation negative regulation of transcription by RNA polymerase II nucleosome assembly positive regulation of transcription by RNA polymerase II regulation of DNA-templated DNA replication initiatio... |
cerebral cortex cell migration chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger learning long-term synaptic potentiation negative regulation of acetylcholine secretion, neurotransmission negative regulation of gamma-aminobutyric acid secretion ne... | cilium; dendrite; plasma membrane; synapse | G protein-coupled serotonin receptor activity neurotransmitter receptor activity | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MVPEPGPVNS | MVPEPGPVNSSTPAWGPGPPPAPGGSGWVAAALCVVIVLTAAANSLLIVLICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELGKARTPAPGQCRLLASLPFVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTGTAGQALETLQVPRTPRPGMESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIAQAVCDCISPGLFDVLTWLGYCNSTMNPIIY... | cerebral cortex cell migration chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger learning long-term synaptic potentiation negative regulation of acetylcholine secretion, neurotransmission negative regulation of gamma-aminobutyric acid secretion ne... |
calcium ion import cellular response to histamine G protein-coupled receptor signaling pathway inflammatory response manganese ion transmembrane transport phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of vasoconstriction regulation of vascular permeability | plasma membrane | calcium ion transmembrane transporter activity histamine receptor activity | Cavia porcellus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MSFLPGMTPV | MSFLPGMTPVTLSNFSWALEDRMLEGNSTTTPTRQLMPLVVVLSSVSLVTVALNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMSILYLHRSAWILGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLRYRTKTRASATILGAWLLSFLWVIPILGWHHFMAPTSEPREKKCETDFYDVTWFKVMTAIINFYLPTLLMLWFYIRIYKAVRRHCQHRQLINSSLPSFSEMKLKLENAKVDTRRMGKESPWEDPKRCSKDASGVHTPMPSSQHLVDMPCAAVLSEDEGGEVGTRQMPMLAVGDGR... | calcium ion import cellular response to histamine G protein-coupled receptor signaling pathway inflammatory response manganese ion transmembrane transport phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of vasoconstriction regulation of vascular permeability plasma membrane c... |
cellular response to histamine chemical synaptic transmission G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger memory negative regulation of st... | dendrite; plasma membrane; synapse | G protein-coupled serotonin receptor activity histamine binding histamine receptor activity neurotransmitter receptor activity | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MSFANTSSTF | MSFANTSSTFEDKMCEGNRTAMASPQLLPLVVVLSSISLVTVGLNLLVLYAVHSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLIMTKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLRYRTKTRASATILGAWFFSFLWVIPILGWHHFMPPAPELREDKCETDFYNVTWFKIMTAIINFYLPTLLMLWFYVKIYKAVRRHCQHRQLTNGSLPSFSELKLRSDDTKEGAKKPGRESPWGVLKRPSRDPSVGLDQKSTSEDPKMTSPTVFSQEGERETRPCFRLDIMQKQSVAEGDVRGSKA... | cellular response to histamine chemical synaptic transmission G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger memory negative regulation of st... |
cell migration cellular response to glucocorticoid stimulus forebrain development G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway nega... | neuron projection; plasma membrane | neuropeptide binding somatostatin receptor activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MSAPSTLPPG | MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRR... | cell migration cellular response to glucocorticoid stimulus forebrain development G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway nega... |
blood coagulation liver development negative regulation of apoptotic process negative regulation of blood coagulation negative regulation of coagulation negative regulation of inflammatory response positive regulation of establishment of endothelial barrier protein catabolic process proteolysis regulation of circulatin... | endoplasmic reticulum; extracellular space; Golgi apparatus | calcium ion binding oligopeptidase activity peptidase activity protein self-association serine-type endopeptidase activity | Rattus norvegicus | Blood coagulation Calcium Cleavage on pair of basic residues Disulfide bond EGF-like domain Endoplasmic reticulum Gamma-carboxyglutamic acid Glycoprotein Golgi apparatus Hemostasis Hydrolase Hydroxylation Protease Reference proteome Repeat Secreted Serine protease Signal Zymogen | MWQFRIFLLF | MWQFRIFLLFASTWGISGVSAHPDPVFSSSEGAHQVLRVRRANSFLEEVRAGSLERECMEEICDFEEAQEIFQNVEDTLAFWIKYFDGDQCSTPPLDHQCDSPCCGHGTCIDGLGGFSCSCDKGWEGRFCQQEMGFQDCRVKNGGCYHYCLEETRGRRCRCAPGYELADDHMHCRPTVNFPCGKLWKRTDKKRKNFKRDIDPEDEELELGPRIVNGTLTKQGDSPWQAILLDSKKKLACGGVLIHTSWVLTAAHCLESSKKLTVRLGEYDLRRRDPWELDLDIKEVLVHPNYTRSNSDNDIALLRLSQPATLSKTIVPIC... | blood coagulation liver development negative regulation of apoptotic process negative regulation of blood coagulation negative regulation of coagulation negative regulation of inflammatory response positive regulation of establishment of endothelial barrier protein catabolic process proteolysis regulation of circulatin... |
axonogenesis establishment of skin barrier hepatocyte growth factor receptor signaling pathway microtubule depolymerization mitotic cytokinesis mitotic spindle organization negative regulation of microtubule polymerization negative regulation of Rho protein signal transduction negative regulation of stress fiber assemb... | cytoplasm; cytosol; membrane; microtubule; neuron projection | tubulin binding | Gallus gallus | Coiled coil Cytoplasm Cytoskeleton Microtubule Phosphoprotein Reference proteome | MATSDIQVKE | MATSDIQVKELEKRASGQAFELILGPRSKEAAPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKEGKDPGEAETN | axonogenesis establishment of skin barrier hepatocyte growth factor receptor signaling pathway microtubule depolymerization mitotic cytokinesis mitotic spindle organization negative regulation of microtubule polymerization negative regulation of Rho protein signal transduction negative regulation of stress fiber assemb... |
compound eye photoreceptor fate commitment metamorphosis mushroom body development negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of development, heterochronic regulation of transcription by RNA polymerase II | nucleus | nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding zinc ion binding | Drosophila melanogaster | DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MYTQRMFDMW | MYTQRMFDMWSSVTSKLEAHANNLGQSNVQSPAGQNNSSGSIKAQIEIIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNKQCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQREKVEDEVRFHRAQMRAQSDAAPDSSVYDTQTPSSSDQLHHNNYNSYSGGYSNNEVGYGSPYGYSASVTPQQTMQYDISADYVDSTTYEPRSTIIDPEFISHADGDINDVLIKTLAEAHANTNTKLEAVHDMFRKQPDVSRILYYKNLGQEELWLDCAEKLTQMIQNIIEFAKLIPGFMRLSQDDQILLL... | compound eye photoreceptor fate commitment metamorphosis mushroom body development negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of development, heterochronic regulation of transcription by RNA polymerase II nucleus nuclear receptor activi... |
cellular response to peptide proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis | mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); mitochondrial proton-transporting ATP synthase, stator stalk; mitochondrion | protein-containing complex binding proton transmembrane transporter activity | Rattus norvegicus | Acetylation CF(0) Direct protein sequencing Hydrogen ion transport Ion transport Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Transport | MAGRKLALKT | MAGRKLALKTIDWVSFVEIMPQNQKAIGNALKSWNETFHTRLASLSEKPPAIDWAYYRANVDKPGLVDDFKNKYNALKIPVPEDKYTALVDAEEKEDVKNCAQFVTGSQARVREYEKQLEKIKNMIPFDQMTIDDLNEVFPETKLDKRKYPYWPHQPIENL | cellular response to peptide proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); mitochondrial proton-transporti... |
cellular response to increased oxygen levels intracellular iron ion homeostasis pH reduction proton transmembrane transport | clathrin-coated vesicle membrane; cytosol; lysosome; plasma membrane; transport vesicle; vacuolar proton-transporting V-type ATPase, V1 domain | ATP binding ATP hydrolysis activity proton-transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism | Bos taurus | 3D-structure ATP-binding Cytoplasm Cytoplasmic vesicle Hydrogen ion transport Ion transport Lysosome Membrane Nucleotide-binding Phosphoprotein Reference proteome Translocase Transport | MDFSKLPKIR | MDFSKLPKIRDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDVKWDFTPCKNLRVGSHITGGDIYGIVNENSLIKHKIMLPPRNRGTVTYIAPPGNYDTSDVVLELEFEGIKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPV... | cellular response to increased oxygen levels intracellular iron ion homeostasis pH reduction proton transmembrane transport clathrin-coated vesicle membrane; cytosol; lysosome; plasma membrane; transport vesicle; vacuolar proton-transporting V-type ATPase, V1 domain ATP binding ATP hydrolysis activity proton-transporti... |
adult behavior ATP metabolic process calcium ion homeostasis chloride ion homeostasis inner ear morphogenesis olfactory behavior ossification pH reduction potassium ion homeostasis prostaglandin metabolic process proton transmembrane transport regulation of gene expression regulation of pH renal sodium excretion renal ... | apical plasma membrane; basolateral plasma membrane; cytoplasm; cytosol; lateral plasma membrane; microvillus; presynapse; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V1 domain | ATP binding proton transmembrane transporter activity proton-transporting ATPase activity, rotational mechanism | Bos taurus | ATP-binding Cell membrane Direct protein sequencing Hydrogen ion transport Ion transport Membrane Nucleotide-binding Reference proteome Transport | MAAEVDSRPR | MAAEVDSRPRGLPGGGASLGAAREHVQAVTRNYITHPRITYRTVCSVNGPLVVLDQVKFAQYAEIVNFTLPNGTQRSGQVLEVSGTKAIVQVFEGTSGIDAQKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAEDFLDINGQPINPHDRIYPEEMIETGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGY... | adult behavior ATP metabolic process calcium ion homeostasis chloride ion homeostasis inner ear morphogenesis olfactory behavior ossification pH reduction potassium ion homeostasis prostaglandin metabolic process proton transmembrane transport regulation of gene expression regulation of pH renal sodium excretion renal ... |
ATP metabolic process pH reduction proton transmembrane transport synaptic vesicle lumen acidification vacuolar acidification | apical plasma membrane; clathrin-coated vesicle membrane; cytosol; melanosome; microvillus; plasma membrane; ruffle; synaptic vesicle membrane; vacuolar proton-transporting V-type ATPase, V1 domain | ATP binding proton-transporting ATPase activity, rotational mechanism | Bos taurus | 3D-structure ATP-binding Cell membrane Cytoplasm Cytoplasmic vesicle Direct protein sequencing Hydrogen ion transport Ion transport Membrane Nucleotide-binding Reference proteome Synapse Transport | MALRAMRGIV | MALRAMRGIVNGAAPELPVPTSGPLAGSREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGR... | ATP metabolic process pH reduction proton transmembrane transport synaptic vesicle lumen acidification vacuolar acidification apical plasma membrane; clathrin-coated vesicle membrane; cytosol; melanosome; microvillus; plasma membrane; ruffle; synaptic vesicle membrane; vacuolar proton-transporting V-type ATPase, V1 dom... |
ATP metabolic process proton transmembrane transport vacuolar acidification | brush border; cytosol; early endosome; perinuclear region of cytoplasm; plasma membrane; plasma membrane proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V1 domain | ATP binding proton-transporting ATPase activity, rotational mechanism | Drosophila melanogaster | ATP-binding Hydrogen ion transport Ion transport Nucleotide-binding Reference proteome Transport | MNAQQAQREH | MNAQQAQREHVLAVSRDFISQPRLTYKTVSGVNGPLVILDEVKFPKFAEIVQLRLADGTVRSGQVLEVSGSKAVVQVFEGTSGIDAKNTLCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPPILAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKLPGKSVLDDHTDNFAIVFAAMGVNMETARFFKQDFEENGSMENVCLFLNLANDPTIERIITPRLALTAAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGR... | ATP metabolic process proton transmembrane transport vacuolar acidification brush border; cytosol; early endosome; perinuclear region of cytoplasm; plasma membrane; plasma membrane proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V1 domain ATP binding proton-transporting ATPase act... |
endosomal lumen acidification Golgi lumen acidification proton transmembrane transport vacuolar acidification | fungal-type vacuole membrane; Golgi membrane; proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V1 domain | ATP binding proton-transporting ATPase activity, rotational mechanism | Saccharomyces cerevisiae | 3D-structure Acetylation ATP-binding Direct protein sequencing Hydrogen ion transport Ion transport Membrane Nucleotide-binding Reference proteome Transport Vacuole | MATALYTAND | MATALYTANDFILISLPQNAQPVTAPGSKTDSWFNETLIGGRAFVSDFKIPEFKIGSLDTLIVESEELSKVDNQIGASIGKIIEILQGLNETSTNAYRTLPINNMPVPEYLENFQWQTRKFKLDKSIKDLITLISNESSQLDADVRATYANYNSAKTNLAAAERKKTGDLSVRSLHDIVKPEDFVLNSEHLTTVLVAVPKSLKSDFEKSYETLSKNVVPASASVIAEDAEYVLFNVHLFKKNVQEFTTAAREKKFIPREFNYSEELIDQLKKEHDSAASLEQSLRVQLVRLAKTAYVDVFINWFHIKALRVYVESVLRYG... | endosomal lumen acidification Golgi lumen acidification proton transmembrane transport vacuolar acidification fungal-type vacuole membrane; Golgi membrane; proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V1 domain ATP binding pro... |
auxin polar transport cell wall pectin metabolic process establishment or maintenance of transmembrane electrochemical gradient leaf development regulation of starch metabolic process response to salt stress response to water deprivation sucrose metabolic process | chloroplast; chloroplast envelope; endosome membrane; extracellular region; Golgi apparatus; mitochondrion; plant-type vacuole; plant-type vacuole membrane; plasma membrane; vacuolar membrane; vacuole | diphosphate hydrolysis-driven proton transmembrane transporter activity inorganic diphosphate phosphatase activity metal ion binding mRNA binding | Arabidopsis thaliana | Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Endosome Hydrogen ion transport Ion transport Magnesium Membrane Metal-binding Reference proteome Translocase Transmembrane Transmembrane helix Transport Vacuole | MVAPALLPEL | MVAPALLPELWTEILVPICAVIGIAFSLFQWYVVSRVKLTSDLGASSSGGANNGKNGYGDYLIEEEEGVNDQSVVAKCAEIQTAISEGATSFLFTEYKYVGVFMIFFAAVIFVFLGSVEGFSTDNKPCTYDTTRTCKPALATAAFSTIAFVLGAVTSVLSGFLGMKIATYANARTTLEARKGVGKAFIVAFRSGAVMGFLLAASGLLVLYITINVFKIYYGDDWEGLFEAITGYGLGGSSMALFGRVGGGIYTKAADVGADLVGKIERNIPEDDPRNPAVIADNVGDNVGDIAGMGSDLFGSYAEASCAALVVASISSFG... | auxin polar transport cell wall pectin metabolic process establishment or maintenance of transmembrane electrochemical gradient leaf development regulation of starch metabolic process response to salt stress response to water deprivation sucrose metabolic process chloroplast; chloroplast envelope; endosome membrane; ex... |
endoplasmic reticulum organization positive regulation of release of sequestered calcium ion into cytosol positive regulation of store-operated calcium channel activity protein polymerization regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion regulation of store-operated calci... | endoplasmic reticulum; mitochondrial matrix; mitochondrion; sarcoplasmic reticulum; sarcoplasmic reticulum lumen; sarcoplasmic reticulum membrane; smooth endoplasmic reticulum; T-tubule; terminal cisterna lumen; Z disc | calcium ion binding identical protein binding | Homo sapiens | 3D-structure Calcium Direct protein sequencing Disease variant Endoplasmic reticulum Glycoprotein Membrane Metal-binding Mitochondrion Muscle protein Phosphoprotein Reference proteome Sarcoplasmic reticulum Signal | MSATDRMGPR | MSATDRMGPRAVPGLRLALLLLLVLGTPKSGVQGQEGLDFPEYDGVDRVINVNAKNYKNVFKKYEVLALLYHEPPEDDKASQRQFEMEELILELAAQVLEDKGVGFGLVDSEKDAAVAKKLGLTEVDSMYVFKGDEVIEYDGEFSADTIVEFLLDVLEDPVELIEGERELQAFENIEDEIKLIGYFKSKDSEHYKAFEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAFMEEPVTIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIHIVAFAEEADPDGFEFLETLKAVAQDNTENPDLSIIW... | endoplasmic reticulum organization positive regulation of release of sequestered calcium ion into cytosol positive regulation of store-operated calcium channel activity protein polymerization regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion regulation of store-operated calci... |
behavioral response to nicotine G protein-coupled glutamate receptor signaling pathway gene expression glutamate receptor signaling pathway glutamate secretion intracellular glutamate homeostasis long-term synaptic depression positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction pres... | astrocyte projection; axon; dendrite; glutamatergic synapse; neuron projection; plasma membrane; presynaptic membrane | calcium channel regulator activity group II metabotropic glutamate receptor activity scaffold protein binding | Rattus norvegicus | Cell membrane Cell projection Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Signal Synapse Transducer Transmembrane Transmembrane helix | MESLLGFLAL | MESLLGFLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEECGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHSDAPTAVTGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAATQRLNASFTWVASDGWGALESVVAGSERAAEGAITIELA... | behavioral response to nicotine G protein-coupled glutamate receptor signaling pathway gene expression glutamate receptor signaling pathway glutamate secretion intracellular glutamate homeostasis long-term synaptic depression positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction pres... |
G protein-coupled glutamate receptor signaling pathway gene expression modulation of chemical synaptic transmission postsynaptic modulation of chemical synaptic transmission regulation of synaptic transmission, glutamatergic sensory perception of pain | astrocyte projection; axon; dendritic spine; glutamatergic synapse; neuron projection; plasma membrane; postsynaptic density; postsynaptic membrane; presynaptic membrane | calcium channel regulator activity group II metabotropic glutamate receptor activity scaffold protein binding | Rattus norvegicus | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix | MKMLTRLQIL | MKMLTRLQILMLALFSKGFLLSLGDHNFMRREIKIEGDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDNYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKVDEAEYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQKPNARVVVLFMRSDDSRELIAAANRVNASFTWVASDGWGAQESIVKGSEHVAYGA... | G protein-coupled glutamate receptor signaling pathway gene expression modulation of chemical synaptic transmission postsynaptic modulation of chemical synaptic transmission regulation of synaptic transmission, glutamatergic sensory perception of pain astrocyte projection; axon; dendritic spine; glutamatergic synapse; ... |
adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway chemical synaptic transmission G protein-coupled glutamate receptor signaling pathway gamma-aminobutyric acid secretion learning negative regulation of apoptotic process negative regulation of cell population proliferation negative regu... | cerebellar granule cell to Purkinje cell synapse; cytoplasmic vesicle; dendritic shaft; glutamatergic synapse; neuron projection; parallel fiber to Purkinje cell synapse; plasma membrane; presynaptic active zone membrane; terminal bouton | adenylate cyclase inhibiting G protein-coupled glutamate receptor activity calcium-dependent protein binding calmodulin binding G protein-coupled receptor activity glutamate receptor activity | Rattus norvegicus | Cell membrane Direct protein sequencing Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix | MSGKGGWAWW | MSGKGGWAWWWARLPLCLLLSLYAPWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKACGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTLASEGSYGESGVEAFIQKSRENGGVCIAQSVKIPREPKTGEFDKIIKRLLETSNARGIIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKSAP... | adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway chemical synaptic transmission G protein-coupled glutamate receptor signaling pathway gamma-aminobutyric acid secretion learning negative regulation of apoptotic process negative regulation of cell population proliferation negative regu... |
antibiotic metabolic process cellular response to calcium ion cellular response to nitric oxide cellular response to xenobiotic stimulus glutathione catabolic process homocysteine metabolic process inflammatory response leukotriene D4 catabolic process leukotriene metabolic process negative regulation of apoptotic proc... | apical part of cell; apical plasma membrane; cell junction; extracellular space; microvillus membrane; nucleoplasm; plasma membrane; side of membrane | beta-lactamase activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process dipeptidase activity GPI anchor binding metallodipeptidase activity modified amino acid binding zinc ion binding | Mus musculus | Cell membrane Cell projection Dipeptidase Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipid metabolism Lipoprotein Membrane Metal-binding Metalloprotease Protease Reference proteome Signal Zinc | MVIIWWFWSL | MVIIWWFWSLLAICASDSFRDQAVAIMRTTPVIDGHNDLPWQLLNLFNNQLLRPDADLNKLAQTHTNIPKLKAGFVGGQFWSAYMPCDTQNKDAVKRILEQMDVIHRMCQLYPETFMCVTNSSDILQAFRRGKVASLIGVEGGHLIDSSLGVLRTLYHLGMRYLTLTHNCNTPWADNWLVDRGDDEAESHGLSPFGKRLLNEMNRLGVMIDLSHVSVATMKDALQISRAPVIFSHSSAYSLCPHRRNVPDDVLQLVKNTSSLVMVNFFSNFVSCSDSATLPQVADHLDHIKKVAGAGAVGLGGDYDGVTMLPVGLEDVSK... | antibiotic metabolic process cellular response to calcium ion cellular response to nitric oxide cellular response to xenobiotic stimulus glutathione catabolic process homocysteine metabolic process inflammatory response leukotriene D4 catabolic process leukotriene metabolic process negative regulation of apoptotic proc... |
antibiotic metabolic process cellular response to calcium ion cellular response to nitric oxide cellular response to xenobiotic stimulus glutathione catabolic process homocysteine metabolic process inflammatory response leukotriene D4 catabolic process leukotriene metabolic process negative regulation of apoptotic proc... | apical part of cell; apical plasma membrane; extracellular space; microvillus membrane; plasma membrane; side of membrane | beta-lactamase activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process dipeptidase activity GPI anchor binding metallodipeptidase activity modified amino acid binding zinc ion binding | Oryctolagus cuniculus | Cell membrane Cell projection Dipeptidase Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipid metabolism Lipoprotein Membrane Metal-binding Metalloprotease Protease Reference proteome Signal Zinc | MWTSWWLWPL | MWTSWWLWPLVAVCTADSFLDQAVQILRVTPVIDGHNDLPWQLLNKFNNRLQDSRANLTVLADTHTNIPKLRAGFVGGQFWSAYTPCDTQNKDTVRRTLEQMDVVHRMCQLYPETFLCVTDSAGIQQAFREGKVASLIGVEGGHSIDSSLGVLRALYRLGMRYLTLTHNCNTPWADNWLVDRGDDEAQSGGLSVFGQRVVREMNRLGVMIDLAHVSVATMKAALQLSTAPVIFSHSSAFTVCAHKRNVPDDVLQLVKETGSLVMVNFYNDYVSCASEATLSQVADHLDYIKNVAGAAAVRFGGDFDGVTRLPVGLEDVSK... | antibiotic metabolic process cellular response to calcium ion cellular response to nitric oxide cellular response to xenobiotic stimulus glutathione catabolic process homocysteine metabolic process inflammatory response leukotriene D4 catabolic process leukotriene metabolic process negative regulation of apoptotic proc... |
antibiotic metabolic process cellular response to calcium ion cellular response to nitric oxide cellular response to xenobiotic stimulus glutathione catabolic process homocysteine metabolic process inflammatory response leukotriene D4 catabolic process leukotriene metabolic process negative regulation of apoptotic proc... | apical part of cell; apical plasma membrane; cell junction; extracellular space; microvillus membrane; nucleoplasm; plasma membrane; side of membrane | beta-lactamase activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process dipeptidase activity GPI anchor binding metallodipeptidase activity modified amino acid binding zinc ion binding | Rattus norvegicus | Cell membrane Cell projection Dipeptidase Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipid metabolism Lipoprotein Membrane Metal-binding Metalloprotease Protease Reference proteome Signal Zinc | MLIIWWFWSL | MLIIWWFWSLLAICASDSFRNQAENIMRTTPVIDGHNDLPWQMLTLFNNQLRKSEANLSALAETHTNIPKLRAGFVGGQFWSAYMPCDTQNKDAVKRILEQIDVIHRMCQLYPETFECVTNSSDILQAFRRGKVASLIGVEGGHLIDSSLGVLRTLYHLGMRYLTLTHNCNTPWADNWLVDKGDDEAESQGLSPFGKLVLNEMNRLGVMIDLSHVSVATMKDALQLSKAPVIFSHSSAYSVCPHRRNVPDDVLQLVKSTNSLVMVNFYNQFVSCSDSATLSQVADHLDHIKKVAGAGAVGLGGDYDGVTNLPVGLEDVSK... | antibiotic metabolic process cellular response to calcium ion cellular response to nitric oxide cellular response to xenobiotic stimulus glutathione catabolic process homocysteine metabolic process inflammatory response leukotriene D4 catabolic process leukotriene metabolic process negative regulation of apoptotic proc... |
cell migration inner ear receptor cell stereocilium organization negative regulation of T cell proliferation neural tube closure positive regulation of exosomal secretion positive regulation of extracellular exosome assembly positive regulation of focal adhesion assembly positive regulation of stress fiber assembly reg... | cell surface; costamere; extracellular exosome; focal adhesion; Golgi lumen; lysosomal lumen; plasma membrane | fibronectin binding identical protein binding protein kinase C binding thrombospondin receptor activity | Homo sapiens | 3D-structure Alternative splicing Glycoprotein Heparan sulfate Membrane Proteoglycan Reference proteome Secreted Signal Transmembrane Transmembrane helix | MAPARLFALL | MAPARLFALLLFFVGGVAESIRETEVIDPQDLLEGRYFSGALPDDEDVVGPGQESDDFELSGSGDLDDLEDSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEENEVIPKRISPVEESEDVSNKVSMSSTVQGSNIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKDEGSYDLGKKPIYKKAPTNEFYA | cell migration inner ear receptor cell stereocilium organization negative regulation of T cell proliferation neural tube closure positive regulation of exosomal secretion positive regulation of extracellular exosome assembly positive regulation of focal adhesion assembly positive regulation of stress fiber assembly reg... |
adenine transport | plasma membrane | adenine transmembrane transporter activity solute:proton symporter activity | Escherichia coli | Cell inner membrane Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix Transport | MSHQHTTQTS | MSHQHTTQTSGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGLFANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWGAIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMGLKNAGVIVANPETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYNGIVSAPPSVMTVVGHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADEKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESS... | adenine transport plasma membrane adenine transmembrane transporter activity solute:proton symporter activity Escherichia coli Cell inner membrane Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix Transport MSHQHTTQTS MSHQHTTQTSGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSI... |
arachidonic acid secretion cell population proliferation defense response to Gram-positive bacterium inflammatory response intestinal stem cell homeostasis killing of cells of another organism lipid catabolic process negative regulation of cell population proliferation negative regulation of epithelial cell proliferati... | endoplasmic reticulum; extracellular space; mitochondrial outer membrane; mitochondrion; perinuclear region of cytoplasm; plasma membrane; secretory granule | calcium ion binding calcium-dependent phospholipase A2 activity phospholipase A2 activity phospholipid binding | Mus musculus | Antimicrobial Bacteriolytic enzyme Calcium Cell membrane Direct protein sequencing Disulfide bond Growth regulation Hydrolase Inflammatory response Lipid degradation Lipid metabolism Membrane Metal-binding Mitochondrion Mitochondrion outer membrane Phospholipid metabolism Reference proteome Secreted Signal | MKVLLLLAAS | MKVLLLLAASIMAFGSIQVQGNIAQFGEMIRLKTGKRAELSYAFYGCHCGLGGKGSPKDATDRCCVTHDCCYKSLEKSGCGTKLLKYKYSHQGGQITCSANQNSCQKRLCQCDKAAAECFARNKKTYSLKYQFYPNMFCKGKKPKC | arachidonic acid secretion cell population proliferation defense response to Gram-positive bacterium inflammatory response intestinal stem cell homeostasis killing of cells of another organism lipid catabolic process negative regulation of cell population proliferation negative regulation of epithelial cell proliferati... |
apoptotic process mRNA processing negative regulation of cytokine production negative regulation of translation positive regulation of epithelial cell apoptotic process protein localization to cytoplasmic stress granule regulation of alternative mRNA splicing, via spliceosome regulation of mRNA splicing, via spliceosom... | cytoplasm; cytoplasmic stress granule; cytosol; nuclear stress granule; nucleoplasm; nucleus; ribonucleoprotein complex | mRNA 3'-UTR AU-rich region binding mRNA 3'-UTR binding poly(A) binding RNA binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Amyotrophic lateral sclerosis Apoptosis Cytoplasm Disease variant mRNA processing mRNA splicing Neurodegeneration Nucleus Reference proteome Repeat RNA-binding | MEDEMPKTLY | MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPQPYGQWGQWYGNAQQIG... | apoptotic process mRNA processing negative regulation of cytokine production negative regulation of translation positive regulation of epithelial cell apoptotic process protein localization to cytoplasmic stress granule regulation of alternative mRNA splicing, via spliceosome regulation of mRNA splicing, via spliceosom... |
cell adhesion protein secretion by the type V secretion system | cell outer membrane; cell surface | collagen binding | Yersinia enterocolitica | 3D-structure Cell adhesion Cell outer membrane Coiled coil Membrane Plasmid Protein transport Signal Transmembrane Transmembrane beta strand Transport Virulence | MTKDFKISVS | MTKDFKISVSAALISALFSSPYAFADDYDGIPNLTAVQISPNADPALGLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAASTAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTDRENSVSIGHESLNRQLTHLAAGTKDTDAVNVAQLKKEIEKTQENTNKRSAELLANANAYADNKSSSVLGIANNYTDSKSAETLENARKEAFAQSKDVLNMAKAHSNSVARTTLETAEEHANSVARTTLETAEEHANKKSA... | cell adhesion protein secretion by the type V secretion system cell outer membrane; cell surface collagen binding Yersinia enterocolitica3D-structure Cell adhesion Cell outer membrane Coiled coil Membrane Plasmid Protein transport Signal Transmembrane Transmembrane beta strand Transport Virulence MTKDFKISVS MTKDFKISVSA... |
lens induction in camera-type eye liver regeneration negative regulation of DNA-templated transcription negative regulation of gene expression olfactory placode formation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II | nucleus; RNA polymerase II transcription regulator complex; transcription regulator complex | chromatin binding DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding sequence-specific DNA binding signaling receptor binding transcription cis-regulatory re... | Rattus norvegicus | Activator DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | LTPAQQQLLL | LTPAQQQLLLQQAQAQAQLLAAAVQQHSASQQHSAAGATISASAATPMTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHPTTNLQPAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQPQPSITLTSQPTTPTRTIAATPIQTLPQSQTTPKRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAENLSSDSTASSPSALNSPGLGAEGLNRRRKKRTSIETNIRVALEKSFMENQKPTSEDITLIAEQLNMEKEVIRVWFCNRR... | lens induction in camera-type eye liver regeneration negative regulation of DNA-templated transcription negative regulation of gene expression olfactory placode formation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II nucleus... |
energy homeostasis negative regulation of fatty acid oxidation xenobiotic catabolic process | endoplasmic reticulum membrane | flavin adenine dinucleotide binding hypotaurine dehydrogenase activity N,N-dimethylaniline monooxygenase activity NADP binding | Homo sapiens | Endoplasmic reticulum FAD Flavoprotein Membrane Microsome Monooxygenase NADP Oxidoreductase Reference proteome Transmembrane Transmembrane helix | MAKKVAVIGA | MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVTNVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFSETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCCSFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNCILCGAITMKTSVIEFTETSAVFEDGTVEEN... | energy homeostasis negative regulation of fatty acid oxidation xenobiotic catabolic process endoplasmic reticulum membrane flavin adenine dinucleotide binding hypotaurine dehydrogenase activity N,N-dimethylaniline monooxygenase activity NADP binding Homo sapiens Endoplasmic reticulum FAD Flavoprotein Membrane Microsome... |
taurine biosynthetic process | endoplasmic reticulum membrane; intracellular membrane-bounded organelle | albendazole monooxygenase activity flavin adenine dinucleotide binding hypotaurine dehydrogenase activity N,N-dimethylaniline monooxygenase activity NADP binding trimethylamine monooxygenase activity | Homo sapiens | Direct protein sequencing Disease variant Endoplasmic reticulum FAD Flavoprotein Membrane Microsome Monooxygenase NADP Oxidoreductase Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MGKKVAIIGA | MGKKVAIIGAGVSGLASIRSCLEEGLEPTCFEKSNDIGGLWKFSDHAEEGRASIYKSVFSNSSKEMMCFPDFPFPDDFPNFMHNSKIQEYIIAFAKEKNLLKYIQFKTFVSSVNKHPDFATTGQWDVTTERDGKKESAVFDAVMVCSGHHVYPNLPKESFPGLNHFKGKCFHSRDYKEPGVFNGKRVLVVGLGNSGCDIATELSRTAEQVMISSRSGSWVMSRVWDNGYPWDMLLVTRFGTFLKNNLPTAISDWLYVKQMNARFKHENYGLMPLNGVLRKEPVFNDELPASILCGIVSVKPNVKEFTETSAIFEDGTIFE... | taurine biosynthetic process endoplasmic reticulum membrane; intracellular membrane-bounded organelle albendazole monooxygenase activity flavin adenine dinucleotide binding hypotaurine dehydrogenase activity N,N-dimethylaniline monooxygenase activity NADP binding trimethylamine monooxygenase activity Homo sapiens Direc... |
cellular heat acclimation chaperone cofactor-dependent protein refolding post-translational protein targeting to endoplasmic reticulum membrane protein folding in endoplasmic reticulum protein refolding protein unfolding stress granule disassembly trehalose metabolism in response to heat stress | cytoplasm; cytosol; nuclear periphery; nucleus; TRC complex | ADP binding ATP binding ATP hydrolysis activity identical protein binding protein-folding chaperone binding unfolded protein binding | Saccharomyces cerevisiae | 3D-structure Acetylation ATP-binding Chaperone Coiled coil Cytoplasm Isopeptide bond Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Stress response Ubl conjugation | MNDQTQFTER | MNDQTQFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGNTRIDSRGADTNTPLEYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNE... | cellular heat acclimation chaperone cofactor-dependent protein refolding post-translational protein targeting to endoplasmic reticulum membrane protein folding in endoplasmic reticulum protein refolding protein unfolding stress granule disassembly trehalose metabolism in response to heat stress cytoplasm; cytosol; nucl... |
DNA damage response iron import into cell | cytosol; outer membrane-bounded periplasmic space; periplasmic space | ferrochelatase activity heme binding metal ion binding peroxidase activity | Escherichia coli | 3D-structure Heme Iron Lyase Metal-binding Oxidoreductase Periplasm Peroxidase Reference proteome Signal | MQYKDENGVN | MQYKDENGVNEPSRRRLLKVIGALALAGSCPVAHAQKTQSAPGTLSPDARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKADLERLFRLLTQRFAFLTQGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKMTRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFISDHAARSKGKETPINLLGFKDGTANPDSQNDKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQFRVEFWDRTPLKEQQTIFGRDKQTGAPLGMQHEHDVPDYASDPE... | DNA damage response iron import into cell cytosol; outer membrane-bounded periplasmic space; periplasmic space ferrochelatase activity heme binding metal ion binding peroxidase activity Escherichia coli 3D-structure Heme Iron Lyase Metal-binding Oxidoreductase Periplasm Peroxidase Reference proteome Signal MQYKDENGVN M... |
D-methionine transport methionine import across plasma membrane | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane; methionine-importing ABC transporter complex; plasma membrane | L-methionine transmembrane transporter activity | Escherichia coli | 3D-structure Amino-acid transport Cell inner membrane Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix Transport | MSEPMMWLLV | MSEPMMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPGQIIANAKLYRTVSAIVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGYSAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTRK | D-methionine transport methionine import across plasma membrane ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane; methionine-importing ABC transporter complex; plasma membrane L-methionine transmembrane transporter activity Escherichia coli 3D-structure Amino-acid transport... |
thiamine transmembrane transport thiamine transport | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane; outer membrane-bounded periplasmic space | thiamine binding thiamine pyrophosphate binding | Escherichia coli | 3D-structure Direct protein sequencing Periplasm Reference proteome Signal Transport | MLKKCLPLLL | MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAFEADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVAADAVNVPGGWNNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRTSTPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTSPAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWISE... | thiamine transmembrane transport thiamine transport ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane; outer membrane-bounded periplasmic space thiamine binding thiamine pyrophosphate binding Escherichia coli 3D-structure Direct protein sequencing Periplasm Reference proteom... |
4-(trimethylammonio)butanoate transport carnitine metabolic process carnitine transport | plasma membrane | (R)-carnitine:4-(trimethylammonio)butanoate antiporter activity carnitine transmembrane transporter activity transmembrane transporter activity | Escherichia coli | 3D-structure Antiport Cell inner membrane Cell membrane Direct protein sequencing Membrane Reference proteome Transmembrane Transmembrane helix Transport | MKNEKRKTGI | MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFY... | 4-(trimethylammonio)butanoate transport carnitine metabolic process carnitine transport plasma membrane (R)-carnitine:4-(trimethylammonio)butanoate antiporter activity carnitine transmembrane transporter activity transmembrane transporter activity Escherichia coli 3D-structure Antiport Cell inner membrane Cell membrane... |
carnitine catabolic process | cytoplasm | L-carnitine CoA-transferase activity | Escherichia coli | 3D-structure Cytoplasm Direct protein sequencing Reference proteome Transferase | MDHLPMPKFG | MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPEGTQLIHRIECPYGPLVEEKLDAWLATHTIAEVKERFAELNIACA... | carnitine catabolic process cytoplasm L-carnitine CoA-transferase activity Escherichia coli 3D-structure Cytoplasm Direct protein sequencing Reference proteome Transferase MDHLPMPKFG MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNL... |
protein transport vacuolar transport | endoplasmic reticulum; endosome membrane; vacuolar membrane | GTP binding GTPase activity | Arabidopsis thaliana | Endosome GTP-binding Lipoprotein Membrane Nucleotide-binding Prenylation Protein transport Reference proteome Transport | MASSGNKNIN | MASSGNKNINAKLVLLGDVGAGKSSLVLRFVKDQFVEFQESTIGAAFFSQTLAVNDATVKFEIWDTAGQERYHSLAPMYYRGAAAAIIVFDITNQASFERAKKWVQELQAQGNPNMVMALAGNKADLLDARKVSAEEAEIYAQENSLFFMETSAKTATNVKDIFYEIAKRLPRVQPAENPTGMVLPNGPGATAVSSSCCA | protein transport vacuolar transport endoplasmic reticulum; endosome membrane; vacuolar membrane GTP binding GTPase activity Arabidopsis thaliana Endosome GTP-binding Lipoprotein Membrane Nucleotide-binding Prenylation Protein transport Reference proteome Transport MASSGNKNIN MASSGNKNINAKLVLLGDVGAGKSSLVLRFVKDQFVEFQESTI... |
chlorophyll biosynthetic process protoporphyrinogen IX biosynthetic process | chloroplast | glutamate-1-semialdehyde 2,1-aminomutase activity pyridoxal phosphate binding transaminase activity | Nicotiana tabacum | Chlorophyll biosynthesis Chloroplast Isomerase Plastid Porphyrin biosynthesis Pyridoxal phosphate Reference proteome Transit peptide | MAAVNGVGIS | MAAVNGVGISWPSKLTQGQRPKLVFSPSPRRCTPSSSTIKMTASVDEKKKTFTLQKSEEAFSKAKELMPGGVNSPVRAFKSVGGQPIIIDSVKGSRMRDIDGNEYIDYVGSWGPAIIGHADDEVLAALAETMKKGTSFGAPCLLENTLAEMVISAVPSIEMVRFVNSGTEACMGVLRLARAFTGRPKIIKFEGCYHGHADPFLVKAGSGVATLGLPDSPGGPKAATSDTLTAPYNDISAVESLFEEHKGEVAAIILEPVVGNAGFIQPNLDFLAAIRKITKENDALLIFDEVMTGFRLAYGGAQEYFGITPDLTTLGKII... | chlorophyll biosynthetic process protoporphyrinogen IX biosynthetic process chloroplast glutamate-1-semialdehyde 2,1-aminomutase activity pyridoxal phosphate binding transaminase activity Nicotiana tabacum Chlorophyll biosynthesis Chloroplast Isomerase Plastid Porphyrin biosynthesis Pyridoxal phosphate Reference proteo... |
adult behavior cellular response to cocaine cellular response to extracellular stimulus D-aspartate import across plasma membrane glutathione biosynthetic process L-aspartate import across plasma membrane L-aspartate transmembrane transport L-glutamate import across plasma membrane L-glutamate transmembrane transport m... | astrocyte projection; axolemma; axon; cell body; cell surface; dendritic shaft; dendritic spine; glutamatergic synapse; membrane; membrane protein complex; membrane raft; neuron projection terminus; plasma membrane; presynaptic membrane; synapse; vesicle | cysteine transmembrane transporter activity glutamate:sodium symporter activity high-affinity L-glutamate transmembrane transporter activity L-glutamate transmembrane transporter activity metal ion binding monoatomic anion transmembrane transporter activity neutral L-amino acid transmembrane transporter activity | Rattus norvegicus | Alternative splicing Amino-acid transport Cell membrane Chloride Direct protein sequencing Glycoprotein Lipoprotein Membrane Metal-binding Palmitate Phosphoprotein Potassium Reference proteome Sodium Symport Transmembrane Transmembrane helix Transport | MASTEGANNM | MASTEGANNMPKQVEVRMHDSHLSSEEPKHRNLGMRMCDKLGKNLLLSLTVFGVILGAVCGGLLRLAAPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSEEANTTKAVISLLNETMNEAPEETKIVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVI... | adult behavior cellular response to cocaine cellular response to extracellular stimulus D-aspartate import across plasma membrane glutathione biosynthetic process L-aspartate import across plasma membrane L-aspartate transmembrane transport L-glutamate import across plasma membrane L-glutamate transmembrane transport m... |
chloride transmembrane transport cysteine transport D-aspartate import across plasma membrane L-aspartate import across plasma membrane L-glutamate import across plasma membrane L-glutamate transmembrane transport | apical plasma membrane; early endosome membrane; late endosome membrane; neuron projection; plasma membrane; recycling endosome membrane; synapse | chloride transmembrane transporter activity cysteine transmembrane transporter activity glutamate:sodium symporter activity high-affinity L-glutamate transmembrane transporter activity L-glutamate transmembrane transporter activity metal ion binding | Oryctolagus cuniculus | Amino-acid transport Cell membrane Chloride Endosome Glycoprotein Membrane Metal-binding Phosphoprotein Potassium Reference proteome Sodium Symport Synapse Synaptosome Transmembrane Transmembrane helix Transport | MGKPARKGCD | MGKPARKGCDSKRFLKNNWLLLSTVVAVVLGIVIGVLVREYSNLSTLDKFYFAFPGEILMRMLKLVILPLIVSSMITGVAALDSNVSGKIGLRAVLYYFCTTIIAVILGIVLVVSIKPGVTQKVDEIDRTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTTREEVTASDDTGKNGTEESVTAVMTTAVSENRTKEYRVVGLYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFRKLGLYMVTVLSGLAIHSIVILPLIYFIVVRKNPFRFAMGM... | chloride transmembrane transport cysteine transport D-aspartate import across plasma membrane L-aspartate import across plasma membrane L-glutamate import across plasma membrane L-glutamate transmembrane transport apical plasma membrane; early endosome membrane; late endosome membrane; neuron projection; plasma membran... |
fusion of virus membrane with host plasma membrane | host cell plasma membrane; membrane; viral envelope; virion membrane | host cell surface receptor binding sialate 4-O-acetylesterase activity sialate 9-O-acetylesterase activity | Murine coronavirus | 3D-structure Disulfide bond Glycoprotein Hemagglutinin Host cell membrane Host membrane Hydrolase Membrane Signal Transmembrane Transmembrane helix Viral envelope protein Virion | MGCMCIAMAP | MGCMCIAMAPRTLLLLIGCQLVFGFNEPLNIVSHLNDDWFLFGDSRSDCTYVENNGHPKLDWLDLDPKLCNSGRISAKSGNSLFRSFHFIDFYNYSGEGDQVIFYEGVNFSPSHGFKCLAYGDNKRWMGNKARFYARVYEKMAQYRSLSFVNVSYAYGGNAKPTSICKDKTLTLNNPTFISKESNYVDYYYESEANFTLQGCDEFIVPLCVFNGHSKGSSSDPANKYYTDSQSYYNMDTGVLYGFNSTLDVGNTVQNPGLDLTCRYLALTPGNYKAVSLEYLLSLPSKAICLRKPKSFMPVQVVDSRWNSTRQSDNMTAV... | fusion of virus membrane with host plasma membrane host cell plasma membrane; membrane; viral envelope; virion membrane host cell surface receptor binding sialate 4-O-acetylesterase activity sialate 9-O-acetylesterase activity Murine coronavirus 3D-structure Disulfide bond Glycoprotein Hemagglutinin Host cell membran... |
fusion of virus membrane with host plasma membrane | host cell plasma membrane; membrane; viral envelope; virion membrane | host cell surface receptor binding sialate 4-O-acetylesterase activity sialate 9-O-acetylesterase activity sialate O-acetylesterase activity | Murine coronavirus | Disulfide bond Glycoprotein Hemagglutinin Host cell membrane Host membrane Hydrolase Membrane Reference proteome Signal Transmembrane Transmembrane helix Viral envelope protein Virion | MCIAMAPRTL | MCIAMAPRTLLLLIXCQLVFGFNEPLNIVSHLNDDWFLFGDSRSDCTYVENNGHPKLDWLDLDPKLCNSGKISAKSGNSLFRSFHFTDFYNYTGEGDQIVFYEGVNFSPSHGFKCLAHGDNKRWMGNKARFYARVYEKMAQYRSLSFVNVSYAYGGNAKPASICKDNTLTLNNPTFISKESNYVDYYYESEANFTLEGCDEFIVPLCGFNGHSKGSSSDAANKYYTDSQSYYNMDIGVLYGFNSTLDVGNTAKDPGLDLTCRYLALTPGNYKAVSLEYLLSLPSKAICLHKTKRFMPVQVVDSRWSSIRQSDNMTAAACQ... | fusion of virus membrane with host plasma membrane host cell plasma membrane; membrane; viral envelope; virion membrane host cell surface receptor binding sialate 4-O-acetylesterase activity sialate 9-O-acetylesterase activity sialate O-acetylesterase activity Murine coronavirus Disulfide bond Glycoprotein Hemaggluti... |
entry receptor-mediated virion attachment to host cell fusion of virus membrane with host plasma membrane viral entry into host cell viral process | membrane; viral envelope; virion membrane | enzyme binding structural molecule activity | Sheep pulmonary adenomatosis virus | Cleavage on pair of basic residues Coiled coil Fusion of virus membrane with host cell membrane Fusion of virus membrane with host membrane Glycoprotein Host-virus interaction Membrane Oncogene Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral attachment to host entry receptor Viral envelope ... | MPKRRAGFRK | MPKRRAGFRKGWYARQRNSLTHQMQRMTLSEPTSELPTQRQIEALMPYAWNEAHVQPPVTPTNILIMLLLLLQRVQNGAAAAFWAYIPDPPMIQSLGWDREIVPVYVNDTSLLGGKSDIHISPQQANISFYGLTTQYPMCFSYQSQHPHCIQVSADISYPRVTISGIDEKTGKKSYGNGTGPLDIPFCDKHLSIGIGIDTPWTLCRARVASVYNINNANATFLWDWAPGGTPDFPEYRGQHPPIFSVNTAPIYQTELWKLLAAFGHGNSLYLQPNISGTKYGDVGVTGFLYPRACVPYPFMLIQGHMEITLSLNIYHLNC... | entry receptor-mediated virion attachment to host cell fusion of virus membrane with host plasma membrane viral entry into host cell viral process membrane; viral envelope; virion membrane enzyme binding structural molecule activity Sheep pulmonary adenomatosis virus Cleavage on pair of basic residues Coiled coil Fusi... |
viral budding via host ESCRT complex | viral nucleocapsid | nucleic acid binding structural constituent of virion zinc ion binding | Sheep pulmonary adenomatosis virus | 3D-structure Capsid protein Coiled coil Host-virus interaction Lipoprotein Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger | MGHTHSRQLF | MGHTHSRQLFVHMLSVMLKHRGITVSKTKLINFLSFIEEVCPWFPREGTVNLETWKKVGEQIRTHYTLHGPEKVPVETLSFWTLIRDCLDFDNDELKRLGNLLKQEEDPLHTPDSVPSYDPPPPPPPSLKMHPSDNDDSLSSTDEAELDEEAAKYHQEDWGFLAQEKGALTSKDELVECFKNLTIALQNAGIQLPSNNNTFPSAPPFPPAYTPTVMAGLDPPPGFPPPSKHMSPLQKALRQAQRLGEVVSDFSLAFPVFENNNQRYYESLPFKQLKELKIACSQYGPTAPFTIAMIESLGTQALPPNDWKQTARACLSGG... | viral budding via host ESCRT complex viral nucleocapsid nucleic acid binding structural constituent of virion zinc ion binding Sheep pulmonary adenomatosis virus 3D-structure Capsid protein Coiled coil Host-virus interaction Lipoprotein Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting Viral buddin... |
nucleotide metabolic process proteolysis viral process | viral nucleocapsid | aspartic-type endopeptidase activity DNA binding dUTP diphosphatase activity structural constituent of virion zinc ion binding | Sheep pulmonary adenomatosis virus | Aspartyl protease Capsid protein DNA-binding Hydrolase Lipoprotein Magnesium Metal-binding Multifunctional enzyme Myristate Nucleotide metabolism Protease Repeat Ribosomal frameshifting Viral matrix protein Viral nucleoprotein Virion Zinc Zinc-finger | MGHTHSRQLF | MGHTHSRQLFVHMLSVMLKHRGITVSKTKLINFLSFIEEVCPWFPREGTVNLETWKKVGEQIRTHYTLHGPEKVPVETLSFWTLIRDCLDFDNDELKRLGNLLKQEEDPLHTPDSVPSYDPPPPPPPSLKMHPSDNDDSLSSTDEAELDEEAAKYHQEDWGFLAQEKGALTSKDELVECFKNLTIALQNAGIQLPSNNNTFPSAPPFPPAYTPTVMAGLDPPPGFPPPSKHMSPLQKALRQAQRLGEVVSDFSLAFPVFENNNQRYYESLPFKQLKELKIACSQYGPTAPFTIAMIESLGTQALPPNDWKQTARACLSGG... | nucleotide metabolic process proteolysis viral process viral nucleocapsid aspartic-type endopeptidase activity DNA binding dUTP diphosphatase activity structural constituent of virion zinc ion binding Sheep pulmonary adenomatosis virus Aspartyl protease Capsid protein DNA-binding Hydrolase Lipoprotein Magnesium Metal-... |
transport of virus in host, cell to cell | host cell plasmodesma; T=3 icosahedral viral capsid | DNA binding GTP binding RNA binding structural molecule activity | Cowpea severe mosaic virus | Alternative initiation Capsid protein Direct protein sequencing DNA-binding GTP-binding Host cell junction Nucleotide-binding RNA-binding Suppressor of RNA silencing T=3 icosahedral capsid protein Transport Viral movement protein Virion | MSTFRYKCKQ | MSTFRYKCKQLDQEIQWWFSGTGNRAFWKFEKKLAELHEWYWSLALDPFPYSGFFYKCFYELFQLWVKLGLIVQVSYLILLLDFFVYTIPKKMASQIETTVEKVKQSGIPADILRKRAVDYWKKNNSHNSQMQDVLPNVDEIYEGMRANIAKYLGRSSTVTSIAKLGKCKVYRKKNIPLANLPSLQTSCVPITLTEESVGNSDYTTEETNSEVKSLHVGAIEIVMNSFASSDCNILGGFLLIDTCHTDINNAIRSIFVAPMRGGRPIRMISFPDTLVQIEPNMNKRFQLLCTTSNGDFMQGRDLAMMHVNVLAHAVTHTS... | transport of virus in host, cell to cell host cell plasmodesma; T=3 icosahedral viral capsid DNA binding GTP binding RNA binding structural molecule activity Cowpea severe mosaic virus Alternative initiation Capsid protein Direct protein sequencing DNA-binding GTP-binding Host cell junction Nucleotide-binding RNA-bind... |
viral budding via host ESCRT complex | host cell cytoplasm; host cell nucleus; host cell plasma membrane; membrane; viral nucleocapsid | RNA binding structural molecule activity zinc ion binding | Simian immunodeficiency virus | Capsid protein Host cell membrane Host cytoplasm Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc ... | MGARSSVLSG | MGARSSVLSGKKADELEKVRLRPGGKKKYMLKHVVWAANELDRFGLAESLLESKEGCQKILTVLEPLVPTGSENLKSLFNTVCVIWCIHAEEKVKHTEEAKQVVKRHLVVETGTADKMPATSRPTAPPSGRGGNYPVQQVGGNYVHLPLSPRTLNAWVKLVEEKKFGAEVVSGFQALSEGCTPYDINQMLNCVGEHQAAMQIIREIINEEAADWDVQHPQPGPLPAGQLREPSGSDIAGTTSTVEEQIQWMHRQQNPIPVGNIYRRWIQLGLQKCVRMYNPVNILDIKQGPKEPFQSYVDRFYKSLRAEQADPAVKNWMT... | viral budding via host ESCRT complex host cell cytoplasm; host cell nucleus; host cell plasma membrane; membrane; viral nucleocapsid RNA binding structural molecule activity zinc ion binding Simian immunodeficiency virus Capsid protein Host cell membrane Host cytoplasm Host membrane Host nucleus Host-virus interactio... |
fucose transmembrane transport glucose transmembrane transport inositol metabolic process myo-inositol transport pentose transmembrane transport peripheral nervous system development polyol transmembrane transport positive regulation of protein localization to membrane positive regulation of reactive oxygen species bio... | apical plasma membrane; basolateral plasma membrane; perinuclear region of cytoplasm; plasma membrane; voltage-gated potassium channel complex | fucose transmembrane transporter activity glucose:sodium symporter activity myo-inositol:sodium symporter activity pentose transmembrane transporter activity polyol transmembrane transporter activity potassium channel regulator activity transmembrane transporter binding | Canis lupus familiaris | Cell membrane Glycoprotein Ion transport Membrane Phosphoprotein Reference proteome Sodium Sodium transport Symport Transmembrane Transmembrane helix Transport | MRAVLETADI | MRAVLETADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIVGALTLMIISMMEIGGFEEVKRRYMLASPNVTSILLTYNLSNTNSCNVHPKKDALKMLRNPTDEDVPWPGFVLGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMIS... | fucose transmembrane transport glucose transmembrane transport inositol metabolic process myo-inositol transport pentose transmembrane transport peripheral nervous system development polyol transmembrane transport positive regulation of protein localization to membrane positive regulation of reactive oxygen species bio... |
alpha-glucoside transport carbohydrate metabolic process glucose import across plasma membrane hexose transmembrane transport renal glucose absorption sodium ion import across plasma membrane sodium ion transport | apical plasma membrane; extracellular exosome; membrane; plasma membrane | alpha-glucoside transmembrane transporter activity D-glucose transmembrane transporter activity glucose:sodium symporter activity low-affinity glucose:sodium symporter activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Disease variant Glycoprotein Ion transport Membrane Reference proteome Sodium Sodium transport Sugar transport Symport Transmembrane Transmembrane helix Transport | MEEHTEAGSA | MEEHTEAGSAPEMGAQKALIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNISSFCYRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCILCGYL... | alpha-glucoside transport carbohydrate metabolic process glucose import across plasma membrane hexose transmembrane transport renal glucose absorption sodium ion import across plasma membrane sodium ion transport apical plasma membrane; extracellular exosome; membrane; plasma membrane alpha-glucoside transmembrane tran... |
alanine transport amino acid import across plasma membrane amino acid transport gamma-aminobutyric acid import import across plasma membrane modulation of chemical synaptic transmission neurotransmitter transport nitrogen compound transport positive regulation of cell differentiation sodium ion transmembrane transport ... | apical plasma membrane; basolateral plasma membrane; dendrite; GABA-ergic synapse; membrane; microvillus membrane; neuronal cell body; plasma membrane; plasma membrane protein complex; postsynaptic membrane | alanine transmembrane transporter activity amino acid transmembrane transporter activity amino acid:sodium symporter activity gamma-aminobutyric acid transmembrane transporter activity gamma-aminobutyric acid:sodium:chloride symporter activity taurine transmembrane transporter activity taurine:sodium symporter activity... | Homo sapiens | Alternative splicing Cardiomyopathy Cell membrane Disease variant Glycoprotein Membrane Neurotransmitter transport Phosphoprotein Reference proteome Symport Transmembrane Transmembrane helix Transport | MATKEKLQCL | MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKY... | alanine transport amino acid import across plasma membrane amino acid transport gamma-aminobutyric acid import import across plasma membrane modulation of chemical synaptic transmission neurotransmitter transport nitrogen compound transport positive regulation of cell differentiation sodium ion transmembrane transport ... |
alanine transport amino acid import across plasma membrane beta-alanine transport gamma-aminobutyric acid import import across plasma membrane modulation of chemical synaptic transmission neurotransmitter transport nitrogen compound transport positive regulation of cell differentiation sodium ion transmembrane transpor... | apical plasma membrane; basolateral plasma membrane; dendrite; GABA-ergic synapse; microvillus membrane; neuronal cell body; plasma membrane; plasma membrane protein complex; postsynaptic membrane | alanine transmembrane transporter activity amino acid transmembrane transporter activity amino acid:sodium symporter activity beta-alanine transmembrane transporter activity gamma-aminobutyric acid transmembrane transporter activity gamma-aminobutyric acid:sodium:chloride symporter activity taurine binding taurine tran... | Rattus norvegicus | Cell membrane Glycoprotein Membrane Neurotransmitter transport Phosphoprotein Reference proteome Symport Transmembrane Transmembrane helix Transport | MATKEKLQCL | MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEADGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEVIIGQYTSEGGITCWEKICPLFSGIGYASIVIVSLLNVYYIVILAWATYYLFQSFQKDLPWAHCNHSWNTPQCMEDTLRRNESHWVSLSAANFTSPVIEFWERNVLSLSSGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGEGIKFYLYPNISRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKY... | alanine transport amino acid import across plasma membrane beta-alanine transport gamma-aminobutyric acid import import across plasma membrane modulation of chemical synaptic transmission neurotransmitter transport nitrogen compound transport positive regulation of cell differentiation sodium ion transmembrane transpor... |
associative learning behavioral fear response chloride transmembrane transport cochlea development gamma-aminobutyric acid signaling pathway inner ear receptor cell development innervation regulation of postsynaptic membrane potential signal transduction synaptic transmission, GABAergic | chloride channel complex; cytosol; dendrite membrane; GABA-A receptor complex; GABA-ergic synapse; neuron projection; neuronal cell body membrane; nucleoplasm; plasma membrane; postsynapse; postsynaptic specialization membrane; presynaptic membrane; synapse | GABA receptor binding GABA-A receptor activity GABA-gated chloride ion channel activity inhibitory extracellular ligand-gated monoatomic ion channel activity ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential signaling receptor activity transmitter-gated monoatomic ion... | Homo sapiens | 3D-structure Cell membrane Chloride Chloride channel Disease variant Disulfide bond Epilepsy Glycoprotein Ion channel Ion transport Isopeptide bond Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport Ubl conjugation | MDNGMFSGFI | MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAM... | associative learning behavioral fear response chloride transmembrane transport cochlea development gamma-aminobutyric acid signaling pathway inner ear receptor cell development innervation regulation of postsynaptic membrane potential signal transduction synaptic transmission, GABAergic chloride channel complex; cytoso... |
brain morphogenesis cellular response to cGMP cellular response to retinoic acid circadian rhythm enteric nervous system development membrane depolarization memory monoamine transport negative regulation of cerebellar granule cell precursor proliferation negative regulation of neuron differentiation negative regulation... | endomembrane system; endosome membrane; focal adhesion; membrane raft; neuron projection; plasma membrane; postsynaptic membrane; presynaptic membrane; serotonergic synapse; synapse | actin filament binding antiporter activity cocaine binding identical protein binding integrin binding monoamine transmembrane transporter activity monoatomic cation channel activity neurotransmitter transmembrane transporter activity nitric-oxide synthase binding serotonin binding serotonin:sodium:chloride symporter ac... | Homo sapiens | 3D-structure Alternative splicing Antiport Cell junction Cell membrane Cell projection Disulfide bond Endosome Glycoprotein Membrane Metal-binding Neurotransmitter transport Phosphoprotein Reference proteome Sodium Synapse Transmembrane Transmembrane helix Transport | METTPLNSQK | METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAVPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKL... | brain morphogenesis cellular response to cGMP cellular response to retinoic acid circadian rhythm enteric nervous system development membrane depolarization memory monoamine transport negative regulation of cerebellar granule cell precursor proliferation negative regulation of neuron differentiation negative regulation... |
amino acid import across plasma membrane creatine transmembrane transport gamma-aminobutyric acid import monocarboxylic acid transport neurotransmitter transport nitrogen compound transport sodium ion transmembrane transport taurine transport | basolateral plasma membrane; plasma membrane | amino acid binding amino acid transmembrane transporter activity amino acid:sodium symporter activity creatine transmembrane transporter activity gamma-aminobutyric acid transmembrane transporter activity gamma-aminobutyric acid:sodium:chloride symporter activity monocarboxylic acid transmembrane transporter activity t... | Rattus norvegicus | Cell membrane Disulfide bond Glycoprotein Membrane Neurotransmitter transport Phosphoprotein Reference proteome Symport Transmembrane Transmembrane helix Transport | MDNRVSGTTS | MDNRVSGTTSNGETKPVCPVMEKVEEDGTLEREQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRKICPIFEGIGYASQMIVSLLNVYYIVVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKTNNSLNVTSENATSPVIEFWERRVLKISDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCVALCIL... | amino acid import across plasma membrane creatine transmembrane transport gamma-aminobutyric acid import monocarboxylic acid transport neurotransmitter transport nitrogen compound transport sodium ion transmembrane transport taurine transport basolateral plasma membrane; plasma membrane amino acid binding amino acid tr... |
monocarboxylic acid transport neurotransmitter transport neurotransmitter uptake response to xenobiotic stimulus sodium ion transmembrane transport | cell projection; GABA-ergic synapse; plasma membrane; postsynaptic membrane; presynaptic membrane; synapse | amino acid binding amino acid:sodium symporter activity gamma-aminobutyric acid:sodium:chloride symporter activity monocarboxylic acid transmembrane transporter activity taurine:sodium symporter activity | Rattus norvegicus | Cell membrane Glycoprotein Membrane Neurotransmitter transport Phosphoprotein Reference proteome Symport Transmembrane Transmembrane helix Transport | MTAEQALPLG | MTAEQALPLGNGKAAEEARGSEALGGGGGGAAGTREARDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRRVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTEKCVEFQKLNFSNYSHVSLQNATSPVMEFWERRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNN... | monocarboxylic acid transport neurotransmitter transport neurotransmitter uptake response to xenobiotic stimulus sodium ion transmembrane transport cell projection; GABA-ergic synapse; plasma membrane; postsynaptic membrane; presynaptic membrane; synapse amino acid binding amino acid:sodium symporter activity gamma-ami... |
associative learning chloride transmembrane transport gamma-aminobutyric acid import inorganic anion import across plasma membrane learning memory negative regulation of synaptic transmission, GABAergic neurotransmitter reuptake positive regulation of gamma-aminobutyric acid secretion response to inorganic substance re... | axon; cell surface; GABA-ergic synapse; neuronal cell body; plasma membrane; postsynaptic membrane; presynaptic membrane | amino acid:sodium symporter activity gamma-aminobutyric acid transmembrane transporter activity gamma-aminobutyric acid:sodium:chloride symporter activity identical protein binding metal ion binding sodium:chloride symporter activity | Mus musculus | Cell membrane Cell projection Disulfide bond Glycoprotein Membrane Metal-binding Neurotransmitter transport Phosphoprotein Reference proteome Sodium Symport Synapse Transmembrane Transmembrane helix Transport | MATDNSKVAD | MATDNSKVADGQISTEVSEAPVASDKPKTLVVKVQKKAGDLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSLVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDS... | associative learning chloride transmembrane transport gamma-aminobutyric acid import inorganic anion import across plasma membrane learning memory negative regulation of synaptic transmission, GABAergic neurotransmitter reuptake positive regulation of gamma-aminobutyric acid secretion response to inorganic substance re... |
amino acid import across plasma membrane creatine transmembrane transport gamma-aminobutyric acid import monocarboxylic acid transport neurotransmitter transport nitrogen compound transport sodium ion transmembrane transport taurine transport | basolateral plasma membrane; plasma membrane | amino acid binding amino acid transmembrane transporter activity amino acid:sodium symporter activity creatine transmembrane transporter activity gamma-aminobutyric acid transmembrane transporter activity gamma-aminobutyric acid:sodium:chloride symporter activity monocarboxylic acid transmembrane transporter activity t... | Mus musculus | Cell membrane Disulfide bond Glycoprotein Membrane Neurotransmitter transport Phosphoprotein Reference proteome Symport Transmembrane Transmembrane helix Transport | MENRASGTTS | MENRASGTTSNGETKPVCPAMEKVEEDGTLEREHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQMIVSLLNVYYIVVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKANDSMNVTSENATSPVIEFWERRVLKLSDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCIL... | amino acid import across plasma membrane creatine transmembrane transport gamma-aminobutyric acid import monocarboxylic acid transport neurotransmitter transport nitrogen compound transport sodium ion transmembrane transport taurine transport basolateral plasma membrane; plasma membrane amino acid binding amino acid tr... |
monocarboxylic acid transport neurotransmitter transport neurotransmitter uptake response to xenobiotic stimulus sodium ion transmembrane transport | cell projection; GABA-ergic synapse; plasma membrane; postsynaptic membrane; presynaptic membrane; synapse | amino acid binding amino acid:sodium symporter activity gamma-aminobutyric acid:sodium:chloride symporter activity monocarboxylic acid transmembrane transporter activity taurine:sodium symporter activity | Mus musculus | Cell membrane Direct protein sequencing Glycoprotein Membrane Neurotransmitter transport Phosphoprotein Reference proteome Symport Transmembrane Transmembrane helix Transport | MTAEQALPLG | MTAEQALPLGNGKAAEEARGSETLGGGGGGAAGTREARDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRRVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTEKCVEFQKLNFSNYSHVSLQNATSPVMEFWERRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNN... | monocarboxylic acid transport neurotransmitter transport neurotransmitter uptake response to xenobiotic stimulus sodium ion transmembrane transport cell projection; GABA-ergic synapse; plasma membrane; postsynaptic membrane; presynaptic membrane; synapse amino acid binding amino acid:sodium symporter activity gamma-ami... |
gamma-aminobutyric acid transport glycine betaine transport intracellular water homeostasis monocarboxylic acid transport neurotransmitter transport sodium ion transmembrane transport | basolateral plasma membrane; plasma membrane | gamma-aminobutyric acid:sodium:chloride symporter activity monocarboxylic acid transmembrane transporter activity | Mus musculus | Cell membrane Disulfide bond Glycoprotein Membrane Neurotransmitter transport Reference proteome Symport Transmembrane Transmembrane helix Transport | MDRKVAVHED | MDRKVAVHEDGYPVVSWVPEEGEMMDQKGKDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFSCGIPVFFLEVALGQYSSQGSVTAWRKICPLLQGIGMASVVIESYLNIYYIIILAWALFYLFSSFTWELPWTTCTNSWNTEHCVDFLNHSSARGVSSSENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIILLIRGVTLPGAYQGIVFYLKPDLLRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYRDSI... | gamma-aminobutyric acid transport glycine betaine transport intracellular water homeostasis monocarboxylic acid transport neurotransmitter transport sodium ion transmembrane transport basolateral plasma membrane; plasma membrane gamma-aminobutyric acid:sodium:chloride symporter activity monocarboxylic acid transmembran... |
brain morphogenesis cellular response to cGMP cellular response to organic substance cellular response to retinoic acid circadian rhythm enteric nervous system development locomotory behavior membrane depolarization memory monoamine transport negative regulation of cerebellar granule cell precursor proliferation negati... | endomembrane system; endosome membrane; focal adhesion; membrane raft; neuron projection; plasma membrane; postsynaptic membrane; presynapse; presynaptic membrane; serotonergic synapse; synapse | actin filament binding antiporter activity cocaine binding identical protein binding integrin binding monoamine transmembrane transporter activity monoatomic cation channel activity neurotransmitter transmembrane transporter activity nitric-oxide synthase binding serotonin binding serotonin:sodium:chloride symporter ac... | Rattus norvegicus | Antiport Cell junction Cell membrane Cell projection Disulfide bond Endosome Glycoprotein Membrane Metal-binding Neurotransmitter transport Phosphoprotein Reference proteome Sodium Synapse Transmembrane Transmembrane helix Transport | METTPLNSQK | METTPLNSQKVLSECKDREDCQENGVLQKGVPTTADRAEPSQISNGYSAVPSTSAGDEASHSIPAATTTLVAEIRQGERETWGKKMDFLLSVIGYAVDLGNIWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIIAWALYYLISSLTDRLPWTSCTNSWNTGNCTNYFAQDNITWTLHSTSPAEEFYLRHVLQIHQSKGLQDLGTISWQLTLCIVLIFTVIYFSIWKGVKTSGKVVWVTATFPYIVLSVLLVRGATLPGAWRGVVFYLKPNWQKL... | brain morphogenesis cellular response to cGMP cellular response to organic substance cellular response to retinoic acid circadian rhythm enteric nervous system development locomotory behavior membrane depolarization memory monoamine transport negative regulation of cerebellar granule cell precursor proliferation negati... |
DNA repair guanine deglycation methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione protein repair response to acidic pH response to methylglyoxal RNA repair | cytoplasm; cytosol | glyoxalase III activity protein deglycase activity protein homodimerization activity thiolester hydrolase activity zinc ion binding | Escherichia coli | 3D-structure Chaperone Cytoplasm Direct protein sequencing DNA damage DNA repair Hydrolase Lyase Metal-binding Reference proteome Stress response Zinc | MTVQTSKNPQ | MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKLLTGDSPFAANALGKLAAQEMLAAYAG | DNA repair guanine deglycation methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione protein repair response to acidic pH response to methylglyoxal RNA repair cytoplasm; cytosol glyoxalase III activity protein deglycase activity protein homodimerization activity thiolester hydrolase activity zinc ion b... |
carbohydrate metabolic process propionate metabolic process, methylcitrate cycle tricarboxylic acid cycle | cytoplasm | 2-methylcitrate synthase activity citrate (Si)-synthase activity protein homodimerization activity | Escherichia coli | Direct protein sequencing Reference proteome Transferase Tricarboxylic acid cycle | MSDTTILQNS | MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHYRGYDILDLAKHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPAASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERIQPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSDMYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPVYTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKM... | carbohydrate metabolic process propionate metabolic process, methylcitrate cycle tricarboxylic acid cycle cytoplasm 2-methylcitrate synthase activity citrate (Si)-synthase activity protein homodimerization activity Escherichia coli Direct protein sequencing Reference proteome Transferase Tricarboxylic acid cycle MSDTTI... |
alanine transport brain development glycine transport leucine transport neurotransmitter transport neutral amino acid transport proline transport protein catabolic process sodium ion transmembrane transport | cell projection; GABA-ergic synapse; glutamatergic synapse; plasma membrane; postsynapse; synapse; synaptic vesicle; synaptic vesicle membrane | symporter activity | Rattus norvegicus | Amino-acid transport Cell projection Cytoplasmic vesicle Glycoprotein Ion transport Membrane Neurotransmitter transport Phosphoprotein Reference proteome Sodium Sodium transport Symport Synapse Transmembrane Transmembrane helix Transport | MPKNSKVTQR | MPKNSKVTQREHSNEHVTESVADLLALEEPVDYKQSVLNVAGETGGKQKVAEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSVFYFFKSFQYPLPWSECPVIRNGTVAVVEPECEKSSATTYFWYREALDISNSISESGGLNWKMTVCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFS... | alanine transport brain development glycine transport leucine transport neurotransmitter transport neutral amino acid transport proline transport protein catabolic process sodium ion transmembrane transport cell projection; GABA-ergic synapse; glutamatergic synapse; plasma membrane; postsynapse; synapse; synaptic vesic... |
pantothenate biosynthetic process | cytosol | ATP binding identical protein binding pantoate-beta-alanine ligase activity protein homodimerization activity | Escherichia coli | 3D-structure ATP-binding Cytoplasm Ligase Nucleotide-binding Pantothenate biosynthesis Reference proteome | MLIIETLPLL | MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEAKARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNGTETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIRKMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAGERDLDEIITIAGQELNEKGFRADDIQIRDADTLLEVSETSKRAVILVAAWLGDARLIDNKMVELA | pantothenate biosynthetic process cytosol ATP binding identical protein binding pantoate-beta-alanine ligase activity protein homodimerization activity Escherichia coli 3D-structure ATP-binding Cytoplasm Ligase Nucleotide-binding Pantothenate biosynthesis Reference proteome MLIIETLPLL MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLH... |
ATP generation from poly-ADP-D-ribose DNA ADP-ribosylation DNA repair innate immune response negative regulation of innate immune response negative regulation of transcription by RNA polymerase II positive regulation of double-strand break repair via homologous recombination protein auto-ADP-ribosylation protein poly-A... | chromatin; cytosol; nuclear replication fork; nucleolus; site of double-strand break | damaged DNA binding NAD binding NAD+ ADP-ribosyltransferase activity NAD+- protein-aspartate ADP-ribosyltransferase activity NAD+-protein ADP-ribosyltransferase activity NAD+-protein-glutamate ADP-ribosyltransferase activity NAD+-protein-histidine ADP-ribosyltransferase activity NAD+-protein-serine ADP-ribosyltransfera... | Xenopus laevis | ADP-ribosylation Allosteric enzyme Chromosome Cytoplasm DNA damage DNA repair DNA-binding Glycosyltransferase Immunity Innate immunity Isopeptide bond Metal-binding NAD Nucleotidyltransferase Nucleus Reference proteome Repeat Transcription Transcription regulation Transferase Zinc Zinc-finger | AKSGRASCKK | AKSGRASCKKCGDNIAKESLGLAIMVQSPMFDGKVPHWHHYSCFWKRARVLSQGDIYGYTELRWEDQEMIKKAIETGGAAAGAGGDSKGGKGEMTLNDFAAEYAKSNRSACKGCEQKIEKGQIRISKKSVDVERPQLGMIDRWYHPDCFVSSREELDFLPSYSASQLKGFTILSAEDKDSLKKKLPAVKNEGKRKADEVDGHSAATKKKIKKEKEKESKLEKLLKEQTELIWHIKDELKKVCSTNDLKELLIANKQQVPSGETNIVDRVSDGMAFGALLPCEECSGQFVFKGDAYYCTGDLSAWTKCVAKTQTPNRKDWV... | ATP generation from poly-ADP-D-ribose DNA ADP-ribosylation DNA repair innate immune response negative regulation of innate immune response negative regulation of transcription by RNA polymerase II positive regulation of double-strand break repair via homologous recombination protein auto-ADP-ribosylation protein poly-A... |
cellular response to heat fungal-type cell wall organization positive regulation of autophagy trehalose biosynthetic process trehalose metabolism in response to stress | alpha,alpha-trehalose-phosphate synthase complex (UDP-forming); mitochondrion | alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity trehalose-phosphatase activity | Saccharomyces cerevisiae | Cytoplasm Direct protein sequencing Hydrolase Reference proteome Stress response | MTTTAQDNSP | MTTTAQDNSPKKRQRIINCVTQLPYKIQLGESNDDWKISATTGNSALFSSLEYLQFDSTEYEQHVVGWTGEITRTERNLFTREAKEKPQDLDDDPLYLTKEQINGLTTTLQDHMKSDKEAKTDTTQTAPVTNNVHPVWLLRKNQSRWRNYAEKVIWPTFHYILNPSNEGEQEKNWWYDYVKFNEAYAQKIGEVYRKGDIIWIHDYYLLLLPQLLRMKFNDESIIIGYFHHAPWPSNEYFRCLPRRKQILDGLVGANRICFQNESFSRHFVSSCKRLLDATAKKSKNSSNSDQYQVSVYGGDVLVDSLPIGVNTTQILKDA... | cellular response to heat fungal-type cell wall organization positive regulation of autophagy trehalose biosynthetic process trehalose metabolism in response to stress alpha,alpha-trehalose-phosphate synthase complex (UDP-forming); mitochondrion alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity trehalose-... |
androgen receptor signaling pathway flagellated sperm motility negative regulation of apoptotic process negative regulation of establishment of protein localization to mitochondrion negative regulation of JUN kinase activity negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway negativ... | cytoplasm; cytoplasmic side of endoplasmic reticulum membrane; cytosol; extracellular exosome; membrane; microtubule cytoskeleton; mitochondrion; nucleus; perinuclear region of cytoplasm | ATP binding ATPase activator activity C3HC4-type RING finger domain binding G protein-coupled receptor binding Hsp70 protein binding low-density lipoprotein particle receptor binding metal ion binding protein-folding chaperone binding Tat protein binding ubiquitin protein ligase binding unfolded protein binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Chaperone Cytoplasm Endoplasmic reticulum Lipoprotein Membrane Metal-binding Methylation Microsome Mitochondrion Nucleus Phosphoprotein Prenylation Reference proteome Repeat Zinc Zinc-finger | MVKETTYYDV | MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKNPNEGEKFKQISQAYEVLSDAKKRELYDKGGEQAIKEGGAGGGFGSPMDIFDMFFGGGGRMQRERRGKNVVHQLSVTLEDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRL... | androgen receptor signaling pathway flagellated sperm motility negative regulation of apoptotic process negative regulation of establishment of protein localization to mitochondrion negative regulation of JUN kinase activity negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway negativ... |
complement activation, classical pathway immune response innate immune response inner ear development response to glucocorticoid response to organic substance synapse pruning | collagen trimer; complement component C1 complex; complement component C1q complex; extracellular region; postsynapse; synapse | identical protein binding | Rattus norvegicus | Collagen Complement pathway Direct protein sequencing Disulfide bond Glycoprotein Hydroxylation Immunity Innate immunity Pyrrolidone carboxylic acid Reference proteome Repeat Secreted Signal | MKTQWSEILT | MKTQWSEILTPLLLLLLGLLHVSWAQSSCTGSPGIPGVPGIPGVPGSDGKPGTPGIKGEKGLPGLAGDHGELGEKGDAGIPGIPGKVGPKGPVGPKGAPGPPGPRGPKGGSGDYKATQKVAFSALRTVNSALRPNQAIRFEKVITNVNDNYEPRSGKFTCKVPGLYYFTYHASSRGNLCVNIVRGRDRDRMQKVLTFCDYAQNTFQVTTGGVVLKLEQEEVVHLQATDKNSLLGVEGANSIFTGFLLFPDMDV | complement activation, classical pathway immune response innate immune response inner ear development response to glucocorticoid response to organic substance synapse pruning collagen trimer; complement component C1 complex; complement component C1q complex; extracellular region; postsynapse; synapse identical protein ... |
carbohydrate metabolic process protein glycosylation ubiquitin-dependent ERAD pathway | extracellular region; membrane | calcium ion binding mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | Penicillium citrinum | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Metal-binding Secreted Signal | MRLPVSFPLT | MRLPVSFPLTVLSLLGSTIAHPYGETEAVLRSEPKSNQAKADAVKEAFQHAWNGYMKYAFPHDELTPVSNGHADSRNGWGASAVDALSTAVIMGKADVVNAILEHVADIDFSKTSDTVSLFETTIRYLAGMLSGYDLLQGPAKNLVDNQDLIDGLLDQSRNLADVLKFAFDTPSGVPYNNINITSHGNDGATTNGLAVTGTLVLEWTRLSDLTGDEEYAKLSQKAESYLLKPQPSSSEPFPGLVGSSININDGQFADSRVSWNGGDDSFYEYLIKMYVYDPKRFETYKDRWVLAAESTIKHLKSHPKSRPDLTFLSSYSN... | carbohydrate metabolic process protein glycosylation ubiquitin-dependent ERAD pathway extracellular region; membrane calcium ion binding mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Penicillium citrinum3D-structure Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Metal-binding Secr... |
carbohydrate transport cellular response to high light intensity cellular response to insulin stimulus fat cell differentiation glucose metabolic process glycogen biosynthetic process insulin receptor signaling pathway intracellular signal transduction mammary gland epithelial cell differentiation negative regulation o... | cell cortex; cytosol; early endosome; intracellular membrane-bounded organelle; nucleoplasm; nucleus; plasma membrane; ruffle membrane | ATP binding metal ion binding molecular function activator activity protein serine kinase activity protein serine/threonine kinase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Apoptosis ATP-binding Carbohydrate metabolism Cell membrane Cytoplasm Developmental protein Diabetes mellitus Disease variant Disulfide bond Endosome Glucose metabolism Glycogen biosynthesis Glycogen metabolism Glycoprotein Kinase Manganese Membrane Metal-binding Nucleotide... | MNEVSVIKEG | MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPE... | carbohydrate transport cellular response to high light intensity cellular response to insulin stimulus fat cell differentiation glucose metabolic process glycogen biosynthetic process insulin receptor signaling pathway intracellular signal transduction mammary gland epithelial cell differentiation negative regulation o... |
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